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Matsumoto Naoyuki  松本 直行

… Alternative Names

MATSUMOTO Naoyuki  松本 直行

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Researcher Number 20386080
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-3657-1791
Affiliation (Current) 2025: 鶴見大学, 歯学部, 教授
Affiliation (based on the past Project Information) *help 2022 – 2025: 鶴見大学, 歯学部, 教授
2019 – 2022: 鶴見大学, 歯学部, 准教授
2016 – 2018: 鶴見大学, 歯学部, 学内講師
2011 – 2015: 日本大学, 歯学部, 助教
2008 – 2009: Nihon University, 歯学部, 助教
Review Section/Research Field
Principal Investigator
Pathobiological dentistry/Dental radiology / Morphological basic dentistry / Basic Section 57060:Surgical dentistry-related / Basic Section 57040:Regenerative dentistry and dental engineering-related
Except Principal Investigator
Basic Section 57020:Oral pathobiological science-related / Pathobiological dentistry/Dental radiology / Basic Section 59040:Nutrition science and health science-related / Social dentistry / Surgical dentistry
Keywords
Principal Investigator
組織傷害 / 唾液腺 / 腫瘍間質誘導 / DNA転写調節 / 癌 / 再生 / 脂肪幹細胞 / 間質血管細胞群 / 再生医療 / 口腔乾燥症 … More / 脂肪由来幹細胞 / 口腔病理学 / apoptosis / MUC-1 / EGFR2 / 唾液腺傷害 / 遺伝子改変動物 / 遺伝子改変マウス / 実験腫瘍学 / 診断マーカー / スクリーニング / がん / KRAS / EGFR / 新規遺伝子増幅法 / 遺伝子変異 / 脈管新生 / 間質誘導 / 遺伝子 / 転移 / 腫瘍問質誘導 / 血管新生 / リンパ管新生 … More
Except Principal Investigator
シェーグレン症候群 / 女性ホルモン / EBウイルス / 唾液 / 唾液分泌 / ドライマウス / EBV / オルガノイド / 唾液腺 / SASP因子 / 老化細胞除去薬 / 老化細胞 / p16INK4a / OVX / シェーグレン 症候群 / 唾液分泌障害 / 自己免疫疾患 / エストロゲン / 慢性疲労 / ヘルペスウイルス / 疲労 / フードファクター / ストレス / レスベラトロール / fatique / Epstein-Barr virus / 唾液分泌促進 / 抗酸化物質 / 口腔乾燥症 / 酸化ストレス / フィトケミカル / 唾液分泌低下 / 網羅的解析 / 炎症性サイトカイン / nodマウス / NODマウス / セリン / カロリー制限 / スクリーニング / KRAS / 遺伝子変異 / がん / keratin / HSP / desmoplakin / plectin-1 / lamin / 癌浸潤 / plectin / cytokeratin / SLIPI / myoma disk / 浸潤能 / 3次元培養 / ptoteome / TIMP / MMP / NUSD-1 / SLPI / 3D culture / proteome / 初期浸潤 / 口腔癌 Less
  • Research Projects

    (14 results)
  • Research Products

    (23 results)
  • Co-Researchers

    (17 People)
  •  唾液腺機能低下における老化細胞-脂肪幹細胞の分子相互作用解明と機能回復への応用Principal Investigator

    • Principal Investigator
      松本 直行
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Tsurumi University
  •  Mechanism of Sjögren's syndrome pathogenesis in an EB virus-infected human salivary gland organoid model

    • Principal Investigator
      中山 亮子
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57020:Oral pathobiological science-related
    • Research Institution
      Tsurumi University
  •  老化細胞除去薬によるSjogren症候群の新規治療戦略

    • Principal Investigator
      尾曲 大輔
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57020:Oral pathobiological science-related
    • Research Institution
      Tsurumi University
  •  Elucidation of the mechanism of Sjogren's syndrome pathogenesis by EBV reactivation promoter gene transgenic mice

    • Principal Investigator
      Nakayama Ryoko
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57020:Oral pathobiological science-related
    • Research Institution
      Tsurumi University
  •  Comprehensive analysis of tissue regeneration and promoting factors in a mouse model of salivary gland-specific injury by adipose-derived stem cells.Principal Investigator

    • Principal Investigator
      Matsumoto Naoyuki
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57040:Regenerative dentistry and dental engineering-related
    • Research Institution
      Tsurumi University
  •  Elucidation of the onset mechanism of chronic fatigue mediated by herpes virus and search for its regulator

    • Principal Investigator
      Inoue Hiroko
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Nihon Pharmaceutical University
  •  Generation of salivary gland-specific injury model mouse and elucidation of repair mechanism by EGFR2 / MUC1 pathwayPrincipal Investigator

    • Principal Investigator
      MATSUMOTO Naoyuki
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Tsurumi University
  •  高齢者の唾液分泌促進を目指したフィトケミカルの効果の検討

    • Principal Investigator
      梁 洪淵
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Social dentistry
    • Research Institution
      Tsurumi University
  •  The molecular mechanism of salivary dysfunction amelioration by calorie restriction

    • Principal Investigator
      Saito Ichiro
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Tsurumi University
  •  Development of detection system of oncogene expressionPrincipal Investigator

    • Principal Investigator
      MATSUMOTO Naoyuki
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Nihon University
  •  New 3-dimentional culture model of early invasion of oral cancer based on proteome analysis.

    • Principal Investigator
      KOMIYAMA Kazuo
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Nihon University
  •  Development of detection system of gene mutation and treatment strategy for salivary and oral cancer

    • Principal Investigator
      MUKAE Syotaro
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Nihon University
  •  Novel therapeutic strategy for oral squamous cell carcinoma by targeting angiogenesis signal.Principal Investigator

    • Principal Investigator
      MATSUMOTO Naoyuki
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Nihon University
  •  Influence of histon deacetyrase inhibitor in induction of tumor-associated stroma in oral cancer cell line.Principal Investigator

    • Principal Investigator
      MATSUMOTO Naoyuki
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Nihon University

All 2024 2023 2022 2021 2020 2019 2017 2016 2015 2014 2012 2011 2008 Other

All Journal Article Presentation Patent

  • [Journal Article] Evaluation of the benefits of neutral bicarbonate ionized water baths in an open-label, randomized, crossover trial2024

    • Author(s)
      Ushikoshi-Nakayama Ryoko、Yamazaki Tomoe、Omagari Daisuke、Matsumoto Naoyuki、Inoue Hiroko、Nukuzuma Chiyoko、Nishino Seiji、Saito Ichiro
    • Journal Title

      Scientific Reports

      Volume: 14 Issue: 1 Pages: 1261-1261

    • DOI

      10.1038/s41598-024-51851-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K10002
  • [Journal Article] Retrospective study on the effect of adipose stem cell transplantation on jaw bone regeneration2024

    • Author(s)
      Kizu Yasuhiro、Ishii Ryota、Matsumoto Naoyuki、Saito Ichiro
    • Journal Title

      International Journal of Implant Dentistry

      Volume: 10 Issue: 1 Pages: 3-3

    • DOI

      10.1186/s40729-024-00523-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K10002
  • [Journal Article] Effects of polyphenols in non-centrifugal cane sugar on saliva secretion: <i>in vitro</i> and <i>in vivo</i> experiments and a randomized controlled trial2023

    • Author(s)
      Supriya Shakya、Ushikoshi-Nakayama Ryoko、Yamazaki Tomoe、Omagari Daisuke、Aota Keiko、Inoue Hiroko、Matsumoto Naoyuki、Saito Ichiro
    • Journal Title

      Journal of Clinical Biochemistry and Nutrition

      Volume: 72 Issue: 2 Pages: 171-182

    • DOI

      10.3164/jcbn.22-114

    • ISSN
      0912-0009, 1880-5086
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K09928, KAKENHI-PROJECT-20K10002, KAKENHI-PROJECT-22K09936
  • [Journal Article] Hyperglycemia Induces Generation of Reactive Oxygen Species and Accelerates Apoptotic Cell Death in Salivary Gland Cells2021

    • Author(s)
      Matsumoto Naoyuki、Omagari Daisuke、Ushikoshi-Nakayama Ryoko、Yamazaki Tomoe、Inoue Hiroko、Saito Ichiro
    • Journal Title

      Pathobiology

      Volume: 88 Issue: 3 Pages: 234-241

    • DOI

      10.1159/000512639

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K10002
  • [Journal Article] What Are the Major Causes of Dry Mouth in Elderly Adults?2020

    • Author(s)
      Matsumoto Naoyuki、Ushikoshi-Nakayama Ryoko、Yamazaki Tomoe、Kaneko Mie、Saito Ichiro
    • Journal Title

      Current Oral Health Reports

      Volume: - Issue: 2 Pages: 165-167

    • DOI

      10.1007/s40496-020-00262-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K11633
  • [Journal Article] Pulmonary activation of vitamin D<sub>3</sub> and preventive effect against interstitial pneumonia2019

    • Author(s)
      Tsujino Ichiro、Ushikoshi-Nakayama Ryoko、Yamazaki Tomoe、Matsumoto Naoyuki、Saito Ichiro
    • Journal Title

      Journal of Clinical Biochemistry and Nutrition

      Volume: 65 Issue: 3 Pages: 245-251

    • DOI

      10.3164/jcbn.19-48

    • NAID

      130007740756

    • ISSN
      0912-0009, 1880-5086
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K11633
  • [Journal Article] Effect of gummy candy containing ubiquinol on secretion of saliva: A randomized, double-blind, placebo-controlled parallel-group comparative study and an in vitro study2019

    • Author(s)
      Ushikoshi-Nakayama Ryoko、Ryo Koufuchi、Yamazaki Tomoe、Kaneko Mie、Sugano Tomoko、Ito Yumi、Matsumoto Naoyuki、Saito Ichiro
    • Journal Title

      PLOS ONE

      Volume: 14 Issue: 4 Pages: e0214495-e0214495

    • DOI

      10.1371/journal.pone.0214495

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11633
  • [Journal Article] Evaluation of the effect of a heat-killed lactic acid bacterium, Enterococcus faecalis 2001, on oral candidiasis2019

    • Author(s)
      Yamazaki T.、Ushikoshi-Nakayama R.、Shirone K.、Suzuki M.、Abe S.、Matsumoto N.、Inoue H.、Saito I.
    • Journal Title

      Beneficial Microbes

      Volume: 10 Issue: 6 Pages: 661-669

    • DOI

      10.3920/bm2018.0115

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K11633
  • [Journal Article] Comparison of performance of the 2016 ACR-EULAR classification criteria for primary Sjogren’s syndrome with other sets of criteria in Japanese patients.2017

    • Author(s)
      Tsuboi H., Hagiwara S., Asashima H., Takahashi H., Harota T., Noma H., Umehara H., Kawakami A., Nakamura H., Sano H., Tsubota K., Ozawa Y., Takamura E., Saito I., Inoue H., Nakamura S., Moriyama M., Takeuchi T., Tanaka Y., Hirata S., Mimori T., Matsumoto I., Sumida T.
    • Journal Title

      Ann. Rheum. Dis.

      Volume: 3 Issue: 12 Pages: 2016-210758

    • DOI

      10.1136/annrheumdis-2016-210758

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05020, KAKENHI-PROJECT-26462668, KAKENHI-PROJECT-26670869, KAKENHI-PROJECT-15K11075, KAKENHI-PROJECT-16K11463, KAKENHI-PROJECT-26293430
  • [Journal Article] Rapid and specific screening assay for KRAS oncogene mutation by a novel gene amplification method.2016

    • Author(s)
      Akira Kumasaka, Naoyuki Matsumoto, Shotaro Mukae, Taiichi Kitano, Hiroyasu Noguchi, Hidero Ohki, Kazuo Komiyama, Tomohiro Ando
    • Journal Title

      Anticancer Research

      Volume: 36

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25462934
  • [Journal Article] Sodium Butyrate, a Histone Deacetylase Inhibitor, Regulates Lymphangiogenic Factors in Oral Cancer Cell Line HSC-32014

    • Author(s)
      TAKASHI YAMAMURA, NAOYUKI MATSUMOTO,YASUYOSHI MATSUE , MICHISATO OKUDERA,YOUICHI NISHIKAWA, YOSHIMITSU ABIKO,KAZUO KOMIYAMA
    • Journal Title

      Anticancer Research

      Volume: 34 Pages: 1701-1708

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24593066
  • [Patent] EGFR遺伝子の変異検出方法及びキット2015

    • Inventor(s)
      小宮山一雄、松本直行
    • Industrial Property Rights Holder
      日本大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-098876
    • Filing Date
      2015-05-14
    • Data Source
      KAKENHI-PROJECT-25462934
  • [Presentation] Influence of non-centrifugal cane sugar (NCS) polyphenols on saliva secretion - a randomized controlled trial study2023

    • Author(s)
      Shakya S、Ushikoshi-Nakayama R、Yamazaki T、Omagari D、Matsumoto N、Inoue H、Saito I
    • Organizer
      第23回 抗加齢医学会総会
    • Data Source
      KAKENHI-PROJECT-20K10002
  • [Presentation] Influence of NCS polyphenols on saliva secretion -a randomized controlled trial2023

    • Author(s)
      Supriya Shakya, Ryoko Ushikoshi-Nakayama, Tomoe Yamazaki, Daisuke Omagari, Naoyuki Matsumoto, Hiroko Inoue, Ichiro Saito
    • Organizer
      第23回抗加齢医学会総会
    • Data Source
      KAKENHI-PROJECT-22K09936
  • [Presentation] Possible effects of brown sugar polyphenols on saliva secretion2022

    • Author(s)
      シャッキャ・スプリヤ、中山亮子、山崎智恵、尾曲大輔、松本直行、井上裕子、斎藤一郎
    • Organizer
      第22回抗加齢医学会総会
    • Data Source
      KAKENHI-PROJECT-20K09928
  • [Presentation] 高血糖による酸化ストレスを介した新たな唾液腺組織傷害の成立機序と抗酸化療法の可能性について2022

    • Author(s)
      松本直行
    • Organizer
      第66回日本唾液腺学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K10002
  • [Presentation] 中性重炭酸イオン水の温浴効果2022

    • Author(s)
      中山亮子、山崎智恵、シャッキャ・スプリヤ、尾曲大輔、松本直行、奴久妻智代子、 小松知子、李昌一、井上裕子、斎藤一郎
    • Organizer
      第22回抗加齢医学会総会
    • Data Source
      KAKENHI-PROJECT-20K09928
  • [Presentation] 2型糖尿病の高血糖を介した唾液分泌障害の検討2020

    • Author(s)
      松本 直行, 中山 亮子, 山崎 智恵, 井上 裕子, 斎藤 一郎
    • Organizer
      第20回日本抗加齢医学会総会
    • Data Source
      KAKENHI-PROJECT-20K10002
  • [Presentation] Rapid and specific screening assay for KRAS oncogene mutation by novel gene amplification method.2014

    • Author(s)
      Naoyuki MATSUMOTO, Akira KUMASAKA, Mitchisato OKUDERA, Yasuyoshi, MATSUE, Yoichi NISHIKAWA, Kazuo KOMIYAMA
    • Organizer
      International Congress on Oral Pathologist
    • Place of Presentation
      Istanbul, Republic of Turkey
    • Data Source
      KAKENHI-PROJECT-25462934
  • [Presentation] ヒストン脱アセチル化酵素阻害剤が口腔癌細胞株のVEGF-A転写調節シグナルに及ぼす影響2012

    • Author(s)
      松本直行
    • Organizer
      第66回日本口腔科学会学術集会
    • Place of Presentation
      広島国際会議場(広島)
    • Year and Date
      2012-05-18
    • Data Source
      KAKENHI-PROJECT-23792154
  • [Presentation] ヒストン脱アセチル化酵素阻害剤が口腔癌細胞株の血管・リンパ管誘導に及ぼす影響2011

    • Author(s)
      松本直行
    • Organizer
      第65回 NPO法人 日本口腔科学会学術集会
    • Place of Presentation
      タワーホール船堀 (東京)
    • Data Source
      KAKENHI-PROJECT-23792154
  • [Presentation] COX-2 high expression in the oral squamous epithelium relate to keratinocyte dif ferentiation but not for cell nroliferation2008

    • Author(s)
      Komiyama K, Matsumoto N, et.al.
    • Organizer
      14^<th> International Congress, International Association of Oral Pathologists
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2008-07-23
    • Data Source
      KAKENHI-PROJECT-20791344
  • [Presentation] ヒストン脱アセチル化酵素阻害剤が口腔癌細胞株のVEGF-A転写調節シグナルに及ぼす影響

    • Author(s)
      松本直行
    • Organizer
      第66回日本口腔科学会学術集会
    • Place of Presentation
      広島国際会議場(広島)
    • Data Source
      KAKENHI-PROJECT-23792154
  • 1.  Nakayama Ryoko (50749843)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 10 results
  • 2.  Saito Ichiro (60147634)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 11 results
  • 3.  Inoue Hiroko (50367306)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 8 results
  • 4.  山崎 智恵 (80817122)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 7 results
  • 5.  尾曲 大輔 (10608699)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 6 results
  • 6.  KOMIYAMA Kazuo (00120452)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 7.  梁 洪淵 (10298268)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 8.  内田 仁司 (20736996)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  美島 健二 (50275343)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  MUKAE Syotaro (70553105)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  SEKI Mitsuko (20226640)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  我孫子 宜光 (70050086)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  葉阪 彩加 (30749841)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  岡田 直子 (50636165)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  IWASE Takashi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  ASANO Masatake
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  OOKI Hidero
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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