Ote Manabu 大手学

… Alternative Names

大手学オオテマナブ

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Researcher Number	20386717
Other IDs
Affiliation (Current)	2025: 東京慈恵会医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2018 – 2025: 東京慈恵会医科大学, 医学部, 講師 2016 – 2017: 東京慈恵会医科大学, 医学部, 助教 2014 – 2015: 東北大学, 生命科学研究科, 研究支援者 2013: 東北大学, 薬学研究科(研究院), 助教 2006: 早稲田大, 理工学術院, 助手
Review Section/Research Field	Principal Investigator Basic Section 39050:Insect science-related / Transformative Research Areas, Section (III) / Insect science / Medium-sized Section 39:Agricultural and environmental biology and related fields / Applied entomology Except Principal Investigator Basic Section 49040:Parasitology-related
Keywords	Principal Investigator RNA / ショウジョウバエ / ボルバキア / デングウイルス / ヤブカ / ウイルス / TomO / 共生 / RNA顆粒 / 節足動物媒介性 … More / RNA二次構造 / フロックハウスウイルス / アルボウイルス / 生殖細胞 / 蚊 / 性 / 共生細菌 / nanos / Sex-lethal … More Except Principal Investigator ヤブカ / パラトランスジェネシス / 感染症 / 病原体 / 蚊 / 共生 / 微生物 / コンピテンシー / 複製 / RNA / デングウイルス / 細胞内共生細菌 / ボルバキア / マラリア原虫 / 中腸 / セラチア菌 / 共生微生物 / 節足動物 / 吸血 / 致死 / 感染 / ハマダラカ / 病原性 / ウイルス / 真菌 / 細菌 Less

ボルバキアによる宿主操作を担う相互作用ネットワークの網羅的解明Principal Investigator
- Principal Investigator
  
  大手学
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 39050:Insect science-related
- Research Institution
  Jikei University School of Medicine
共生細菌ボルバキアのゲノム操作による遺伝子機能解析と新規系統の作出Principal Investigator
- Principal Investigator
  
  大手学
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Jikei University School of Medicine
細胞内共生細菌による特殊なRNA高次構造を介した宿主操作Principal Investigator
- Principal Investigator
  
  大手学
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Jikei University School of Medicine
アルボウイルスの特殊なゲノムRNA構造の解析と媒介性の規定要因としての検証Principal Investigator
- Principal Investigator
  
  大手学
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 39:Agricultural and environmental biology and related fields
- Research Institution
  Jikei University School of Medicine
共生細菌ボルバキアによるウイルス抑制・宿主操作の基盤となる分子機構の解明Principal Investigator
- Principal Investigator
  
  大手学
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 39050:Insect science-related
- Research Institution
  Jikei University School of Medicine
Competency control of pathogen vector mosquitoes by paratransgenesis
- Principal Investigator
  
  嘉糠洋陸
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49040:Parasitology-related
- Research Institution
  Jikei University School of Medicine
Paratransgenesis of disease vector mosquito by fungi, bacteria, and cellular symbiont
- Principal Investigator
  
  Kanuka Hirotaka
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49040:Parasitology-related
- Research Institution
  Jikei University School of Medicine
The mechanism of Wolbachia-mediated RNA virus blockingPrincipal Investigator
- Principal Investigator
  
  Ote Manabu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 39050:Insect science-related
- Research Institution
  Jikei University School of Medicine
Host manipulation by the Wolbachia effector protein TomOPrincipal Investigator
- Principal Investigator
  
  Ote Manabu
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Insect science
- Research Institution
  Jikei University School of Medicine
Virus resistance induced by WolbachiaPrincipal Investigator
- Principal Investigator
  
  Ote Manabu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Insect science
- Research Institution
  Tohoku University
共生細菌ヴォルバキアによる宿主操作の分子メカニズムの解明Principal Investigator
- Principal Investigator
  
  大手学
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied entomology
- Research Institution
  Waseda University

All 2023 2022 2021 2020 2019 2018 2017 2016 2013

All Journal Article Presentation

[Journal Article] Association of 410L, 1016I and 1534C kdr mutations with pyrethroid resistance in Aedes aegypti from Ouagadougou, Burkina Faso, and development of a one-step multiplex PCR method for the simultaneous detection of 1534C and 1016I kdr mutations2023
- Author(s)
  Sombie Aboubacar、Ouedraogo Wendegoudi Mathias、Ote Manabu、Saiki Erisha、Sakurai Tatsuya、Yameogo Felix、Sanon Antoine、McCall Philip J.、Kanuka Hirotaka、Weetman David、Badolo Athanase
- Journal Title
  
  Parasites & Vectors
  
  Volume: 16 Issue: 1 Pages: 137-137
- DOI
  10.1186/s13071-023-05743-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24124
[Journal Article] Expression of matrix metalloproteinase genes during basement membrane degradation in the metamorphosis of Bombyx mori2018
- Author(s)
  Kawasaki Hideki、Manickam Asaithambi、Shahin Rima、Ote Manabu、Iwanaga Masashi
- Journal Title
  
  Gene
  
  Volume: 638 Pages: 26-35
- DOI
  10.1016/j.gene.2017.09.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15065
[Journal Article] Wolbachia protein TomO targets nanos mRNA and restores germ stem cells in Drosophila Sex-lethal mutants.2016
- Author(s)
  Ote, M., Ueyama, M., Yamamoto, D.
- Journal Title
  
  Curr. Biol.
  
  Volume: 26 Issue: 17 Pages: 2223-2232
- DOI
  10.1016/j.cub.2016.06.054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14306, KAKENHI-PROJECT-16K15065, KAKENHI-PROJECT-16H06371
[Presentation] 共生細菌ボルバキアにより昆虫のウイルス抵抗性が誘導される仕組みの解明2023
- Author(s)
  大手学、嘉糠洋陸
- Organizer
  第75回日本衛生動物学会大会
- Data Source
  KAKENHI-PROJECT-22K19185
[Presentation] 共生細菌ボルバキアが宿主昆虫にウイルス抵抗性を賦与する仕組みの解明2023
- Author(s)
  大手学・嘉糠洋陸
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K24124
[Presentation] 共生細菌ボルバキアによる昆虫細胞内におけるウイルスRNAの操作と複製阻害2023
- Author(s)
  大手学、嘉糠洋陸
- Organizer
  第67回日本応用動物昆虫学会大会
- Data Source
  KAKENHI-PROJECT-23K23627
[Presentation] 共生細菌ボルバキアによるウイルスRNAの操作2023
- Author(s)
  大手学・嘉糠洋陸
- Organizer
  第67回日本応用動物昆虫学会大会
- Data Source
  KAKENHI-PROJECT-23K24124
[Presentation] 共生細菌ボルバキアにより昆虫のウイルス抵抗性が誘導される仕組みの解明2023
- Author(s)
  大手学・嘉糠洋陸
- Organizer
  第75回日本衛生動物学会大会
- Data Source
  KAKENHI-PROJECT-23K24124
[Presentation] 共生細菌ボルバキアによる昆虫細胞内におけるウイルスRNAの操作と複製阻害2023
- Author(s)
  大手学、嘉糠洋陸
- Organizer
  第67回日本応用動物昆虫学会大会
- Data Source
  KAKENHI-PROJECT-22K19185
[Presentation] 共生細菌ボルバキアによるウイルス複製の阻害機構2022
- Author(s)
  大手学、嘉糠洋陸
- Organizer
  第74回日本衛生動物学会大会
- Data Source
  KAKENHI-PROJECT-22K19185
[Presentation] 共生細菌ボルバキアによるウイルス複製の阻害機構2022
- Author(s)
  大手学、嘉糠洋陸
- Organizer
  第74回日本衛生動物学会
- Data Source
  KAKENHI-PROJECT-23K23627
[Presentation] 共生細菌ボルバキアによるウイルス複製の阻害機構2022
- Author(s)
  大手学・嘉糠洋陸
- Organizer
  第74回日本衛生動物学会大会
- Data Source
  KAKENHI-PROJECT-23K24124
[Presentation] 共生細菌ボルバキアによる昆虫細胞内におけるウイルスRNAの操作と複製阻害2022
- Author(s)
  大手学、嘉糠洋陸
- Organizer
  第67回日本応用動物昆虫学会大会
- Data Source
  KAKENHI-PROJECT-22K19185
[Presentation] ヤブカ細胞における共生細菌ボルバキアによるデングウイルスRNAの制御2021
- Author(s)
  大手学、嘉糠洋陸
- Organizer
  第73回日本衛生動物学会大会
- Data Source
  KAKENHI-PROJECT-19H03462
[Presentation] ヤブカ細胞における共生細菌ボルバキアによるデングウイルスRNAの制御2021
- Author(s)
  大手学、嘉糠洋陸
- Organizer
  第73回日本衛生動物学会大会
- Data Source
  KAKENHI-PROJECT-18H02215
[Presentation] ボルバキアによるデングウイルスRNAの制御2021
- Author(s)
  大手学、嘉糠洋陸
- Organizer
  第65回日本応用動物昆虫学会大会
- Data Source
  KAKENHI-PROJECT-18H02215
[Presentation] ヤブカにおける共生細菌ボルバキアによるRNAウイルスの制御2021
- Author(s)
  大手学
- Organizer
  第72回日本衛生動物学会東日本支部会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03462
[Presentation] Host manipulation by symbiotic bacteria Wolbachia pipientis in Drosophila and Aedes mosquito2021
- Author(s)
  Manabu Ote, Hirotaka Kanuka
- Organizer
  14th Japan Drosophila Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02215
[Presentation] ヤブカにおける共生細菌ボルバキアによるRNAウイルスの制御2021
- Author(s)
  大手学
- Organizer
  第72回日本衛生動物学会東日本支部会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02215
[Presentation] Host manipulation by symbiotic bacteria Wolbachia pipientis in Drosophila and Aedes mosquito2021
- Author(s)
  Manabu Ote, Hirotaka Kanuka
- Organizer
  14th Japan Drosophila Research Conference
- Data Source
  KAKENHI-PROJECT-19H03462
[Presentation] ヤブカと共生細菌ボルバキア由来のデングウイルス制御因子2020
- Author(s)
  大手学、嘉糠洋陸
- Organizer
  第72回日本衛生動物学会大会
- Data Source
  KAKENHI-PROJECT-18H02215
[Presentation] 昆虫共生細菌ボルバキアによるデングウイルスRNAの制御2019
- Author(s)
  大手学、嘉糠洋陸
- Organizer
  第71回日本衛生動物学会大会
- Data Source
  KAKENHI-PROJECT-19H03462
[Presentation] ヤブカにおける共生細菌ボルバキアによるウイルス制御2019
- Author(s)
  大手学、嘉糠洋陸
- Organizer
  第42回日本分子生物学会大会
- Data Source
  KAKENHI-PROJECT-19H03462
[Presentation] Molecular basis of symbiosis between bacteria and insects: Wolbachia colonize Drosophila germline stem cells and target host RNAs2018
- Author(s)
  Manabu Ote
- Organizer
  Neuro Global Focused symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15065
[Presentation] 共生細菌ボルバキアによるRNAウイルス抑制の分子機構2018
- Author(s)
  大手学、嘉糠洋陸
- Organizer
  日本応用動物昆虫学会第62回大会
- Data Source
  KAKENHI-PROJECT-16K15065
[Presentation] Dissecting interaction between arbovirus and symbiotic bacteria Wolbachia in Aedes mosquitoes2017
- Author(s)
  大手学、嘉糠洋陸
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-16K15065
[Presentation] ネッタイシマカでの共生細菌ボルバキアの感染様式2017
- Author(s)
  大手学、嘉糠洋陸
- Organizer
  日本衛生動物学会第69回大会
- Data Source
  KAKENHI-PROJECT-16K15065
[Presentation] Symbiotic bacteria Wolbachia manipulate host germline stem cells by targeting host RNAs2017
- Author(s)
  Manabu Ote
- Organizer
  EMBO Conference Molecular and Population Biology of Mosquitoes and Other Disease Vectors Vector and Disease Control
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15065
[Presentation] Symbiotic bacteria Wolbachia manipulate host germline stem cells by targeting host RNAs: How deep do symbiotic bacteria invade hosts?2017
- Author(s)
  Manabu Ote
- Organizer
  The 3rd Tokyo Vector Encounter
- Place of Presentation
  東京慈恵会医科大学
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15065
[Presentation] Host manipulation by a novel Wolbachia protein TomO2016
- Author(s)
  Manabu Ote, Morio Ueyama, Daisuke Yamamoto
- Organizer
  Wolbachia Conference 2016
- Place of Presentation
  O'Reillys Rainforest Retreat, Australia
- Year and Date
  2016-06-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15065
[Presentation] Genetic analysis of virus resistance induced by symbiotic bacteria Wolbachia2013
- Author(s)
  Manabu OTE, Misaki KURATA and Shoichiro KURATA
- Organizer
  The 36th Annual Meeting of the Molecular Biology Society of Japan
- Place of Presentation
  Kobe Port Island
- Data Source
  KAKENHI-PROJECT-25660262

1. Kanuka Hirotaka (50342770)

# of Collaborated Projects: 5 results

# of Collaborated Products: 19 results
2. 相内大吾 (50552783)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. YAMAMOTO Daisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ote Manabu 大手 学

大手 学 オオテ マナブ

Research Projects

Research Products

Co-Researchers

ボルバキアによる宿主操作を担う相互作用ネットワークの網羅的解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

共生細菌ボルバキアのゲノム操作による遺伝子機能解析と新規系統の作出Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

細胞内共生細菌による特殊なRNA高次構造を介した宿主操作Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

アルボウイルスの特殊なゲノムRNA構造の解析と媒介性の規定要因としての検証Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

共生細菌ボルバキアによるウイルス抑制・宿主操作の基盤となる分子機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Competency control of pathogen vector mosquitoes by paratransgenesis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Paratransgenesis of disease vector mosquito by fungi, bacteria, and cellular symbiont

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The mechanism of Wolbachia-mediated RNA virus blockingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Host manipulation by the Wolbachia effector protein TomOPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Virus resistance induced by WolbachiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

共生細菌ヴォルバキアによる宿主操作の分子メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Association of 410L, 1016I and 1534C kdr mutations with pyrethroid resistance in Aedes aegypti from Ouagadougou, Burkina Faso, and development of a one-step multiplex PCR method for the simultaneous detection of 1534C and 1016I kdr mutations2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression of matrix metalloproteinase genes during basement membrane degradation in the metamorphosis of Bombyx mori2018

Author(s)

Journal Title

DOI

Ote Manabu 大手学

大手学オオテマナブ