TADOKORO Satoshi 田所哲

Researcher Number	20389109
Other IDs
Affiliation (based on the past Project Information) *help	2020 – 2022: 神奈川県衛生研究所, 理化学部, 主任研究員 2014 – 2016: 帝京大学, 薬学部, 講師 2011 – 2013: 名古屋市立大学, 薬学研究科(研究院), 助教 2012: 名古屋市立大学, 大学院・薬学研究科, 助教 2007 – 2008: 名古屋市立大学, 大学院・薬学研究科, 助教
Review Section/Research Field	Principal Investigator Biophysics / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related Except Principal Investigator Biophysics
Keywords	Principal Investigator リポソーム / 開口放出 / 膜融合 / 人工細胞 / SNARE / マスト細胞 / アレルギー / エンドサイトーシス / エキソサイトーシス Except Principal Investigator 免疫学 … More / ラフト / 分泌細胞 / マスト細胞 / 開口放出 / アクティブゾーン / シグナル伝達 / アレルギー Less

抗アレルギー活性を有するIgE標的デコイリポソーム製剤の開発Principal Investigator
- Principal Investigator
  
  田所哲
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Kanagawa Prefectural Institute of Public Health
単一巨大リポソームによる開口放出様の膜融合の可視化解析Principal Investigator
- Principal Investigator
  
  田所哲
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  Teikyo University
Interfacial analysis using artificial exo/endocytotic systems and development of target-specific secretion/uptake systemsPrincipal Investigator
- Principal Investigator
  
  TADOKORO SATOSHI
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biophysics
- Research Institution
  Teikyo University
  Nagoya City University
Stimulation-secretion coupling of artificial secretory cells using cell-sized proteoliposomesPrincipal Investigator
- Principal Investigator
  
  TADOKORO Satoshi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biophysics
- Research Institution
  Nagoya City University
The formation and function of mobile active zone in exocytosis from non-excitable secretory cells
- Principal Investigator
  
  HIRASHIMA Naohide
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  Nagoya City University

All 2016 2015 2014 2013 2012 2011 2009 2008 2007 Other

All Journal Article Presentation Other

[Journal Article] Effect of Complexin II on Membrane Fusion between Liposomes Containing Mast Cell SNARE Proteins2016
- Author(s)
  Satoshi Tadokoro, Naohide Hirashima, Naoko Utsunomiya-Tate
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 39 Issue: 3 Pages: 446-449
- DOI
  10.1248/bpb.b15-00751
- NAID
  130005132308
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07033, KAKENHI-PROJECT-26460041
[Journal Article] Effects of PIP2 on membrane fusion between mast cell SNARE liposomes mediated by synaptotagmin22015
- Author(s)
  Satoshi Tadokoro, Yoshikazu Inoh, Mamoru Nakanishi, Naohide Hirashima
- Journal Title
  
  Biochim. Biophys. Acta-Biomembranes
  
  Volume: 1848 Issue: 10 Pages: 2290-2294
- DOI
  10.1016/j.bbamem.2015.06.016
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07033, KAKENHI-PROJECT-26460041
[Journal Article] 巨大リポソームによるエンド／エクソサイトーシス系のモデル開発2013
- Author(s)
  平嶋尚英、田所　哲
- Journal Title
  
  生物物理
  
  Volume: 53 Pages: 98-100
- NAID
  10031151790
- Data Source
  KAKENHI-PROJECT-25840051
[Journal Article] 巨大リポソームによるエンド/絵くそサイトーシス系のモデル開発2013
- Author(s)
  平嶋尚英、田所哲
- Journal Title
  
  生物物理
  
  Volume: 53 Pages: 98-100
- Data Source
  KAKENHI-PROJECT-23770181
[Journal Article] Inhibitory effects of a cationic liposome on allergic reaction mediated by mast cell activation.2013
- Author(s)
  Yoshikazu Inoh, Satoshi Tadokoro, Hiroki Tanabe, Makoto Inoue, Naohide Hirashima, Tadahide Furuno, Mamoru Nakanishi
- Journal Title
  
  Biochemical Pharmacology
  
  Volume: 86 Issue: 12 Pages: 1731-1738
- DOI
  10.1016/j.bcp.2013.09.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25840051
[Journal Article] Detection of asymmetric distribution of phospholipids by fluorescence resonance energy transfer.2012
- Author(s)
  Yoko Nishimura
- Journal Title
  
  BBRC
  
  Volume: 420 Issue: 4 Pages: 926-30
- DOI
  10.1016/j.bbrc.2012.03.106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770181
[Journal Article] The suppression of IgE-mediated histamine release from mast cells following exocytic exclusion of biodegradable polymeric nanoparticles.2012
- Author(s)
  Tahara K.
- Journal Title
  
  Biomaterials
  
  Volume: 33 Issue: 1 Pages: 343-351
- DOI
  10.1016/j.biomaterials.2011.09.043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590048, KAKENHI-PROJECT-23770181
[Journal Article] Endocytosis-like uptake of surface-modified drug nano-carriers into giant unilamellar vesicles.2012
- Author(s)
  Kohei Tahara
- Journal Title
  
  Langmuir
  
  Volume: 28 Issue: 18 Pages: 7114-8
- DOI
  10.1021/la300902z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770181
[Journal Article] Effects of synaptotagmin II on membrane fusion of liposomes containing SNARE proteins involved in exocytosis in mast cells2011
- Author(s)
  Yumiko Nagai
- Journal Title
  
  BBA-Biomembranes
  
  Volume: 1808 Issue: 10 Pages: 2435-2439
- DOI
  10.1016/j.bbamem.2011.07.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590048, KAKENHI-PROJECT-23770181
[Journal Article] Membrane fusion between liposomes containing SNARE proteins involved in mast cell exocytosis2009
- Author(s)
  H. Sakiyama, S. Tadokoro, M. Nakanishi, N. Hirashima
- Journal Title
  
  Inflamm. Res 58
  
  Pages: 139-142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370064
[Journal Article] Munc18-2 regulates exocytotic membrane fusion positively interacting with syntaxin 3 in RBL-2H3 cells2007
- Author(s)
  S.Tadokoro et al.
- Journal Title
  
  Molecular Immunology (印刷中)
- Data Source
  KAKENHI-PROJECT-18370064
[Journal Article] Munc18-2 regulates exocytotic membrane fusion positively interacting with syntaxin 3 in RBL-2H3 cells2007
- Author(s)
  S. Tadokoro, T. Kurimoto, M. Nakanishi, N. Hirashima
- Journal Title
  
  Mol. Immunol 44
  
  Pages: 3427-3433
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370064
[Journal Article] Involvement of ELKS, an active zone protein, in exocytotic release in RBL-2H3 cells, Cell
- Author(s)
  H. Nomura, T. Ohtsuka, S. Tadokoro, M. Tanaka, N. Hirashima
- Journal Title
  
  Immunol (in press)
- Data Source
  KAKENHI-PROJECT-18370064
[Presentation] マスト細胞のSNARE依存性の膜融合におけるcomplexin IIのclamp効果2016
- Author(s)
  田所哲、平嶋尚英、楯直子
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-15K07033
[Presentation] マスト細胞のSNARE依存性の膜融合におけるcomplexin IIの役割2016
- Author(s)
  田所哲
- Organizer
  第８９回日本生化学会大会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-09-27
- Data Source
  KAKENHI-PROJECT-15K07033
[Presentation] マスト細胞の脱顆粒におけるsyntaxin3のリン酸化の役割2015
- Author(s)
  田所　哲
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-25840051
[Presentation] 正電荷リポソームの物性がマスト細胞の脱顆粒反応抑制経路に及ぼす影響2015
- Author(s)
  伊納義和、谷口奈央、田所哲、中西守、平嶋尚英、古野忠秀
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-15K07033
[Presentation] マスト細胞におけるsyntaxin-3のリン酸化による開口放出制御機構2015
- Author(s)
  田所哲、柴田哲大、天野稔朗、伊納義和、中西守、平嶋尚英、楯直子
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-15K07033
[Presentation] マスト細胞の開口放出におけるsynaptotagmin2の役割とその機能領域2014
- Author(s)
  田所　哲
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-25840051
[Presentation] バイオサーファクタントMELsは、SNAREやMAPキナーゼのリン酸化を抑制することで、マスト細胞からの炎症性メディエーターの分泌を抑制する2012
- Author(s)
  田所　哲
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学
- Data Source
  KAKENHI-PROJECT-23770181
[Presentation] Enhancement effect of synaptotagmin II on SNARE mediated membrane fusion requires Ca2+ and phosphatidylserine2012
- Author(s)
  Satoshi Tadokoro
- Organizer
  2012 The American Society for Cell Biology Annual Meeting
- Place of Presentation
  米国サンフランシスコ
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PROJECT-23770181
[Presentation] マスト細胞の開口放出様の膜融合におけるカルシウムの役割2012
- Author(s)
  田所哲
- Organizer
  第50回日本生物物理学会
- Place of Presentation
  名古屋
- Year and Date
  2012-09-24
- Data Source
  KAKENHI-PROJECT-23770181
[Presentation] Effects of synaptotagmin II on membrane fusion of liposomes containing SNARE proteins involved in exocytosis in mast cells2011
- Author(s)
  Satoshi Tadokoro
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都国際会議場
- Data Source
  KAKENHI-PROJECT-23770181
[Presentation] Functional analysis of synaptotagmin II involved in mast cell exocytosis using in vitro SNARE mediated fusion assay2011
- Author(s)
  Satoshi Tadokoro
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PROJECT-23770181
[Presentation] Effects of synaptotagmin II on membrane fusion of liposomes containing SNARE proteins involved in exocytosis in mast cells2011
- Author(s)
  Satoshi Tadokoro
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-23770181
[Presentation] 膜融合を指標にしたマスト細胞の開口放出因子の機能解析2009
- Author(s)
  田所哲、永井弓子、笹井雅夫、中西守、平嶋尚英
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-18370064
[Presentation] リポソームを用いた人工開口放出系の構築2009
- Author(s)
  平嶋尚英、笹井雅夫、田所哲
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-18370064
[Presentation] Complexinによるマスト細胞の脱顆粒制御2008
- Author(s)
  田所哲、中西守、平嶋尚英
- Organizer
  第30回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  札幌
- Year and Date
  2008-08-08
- Data Source
  KAKENHI-PROJECT-18370064
[Presentation] マスト細胞の脱顆粒に関与するSNARE結合分子による分泌制御機構2008
- Author(s)
  田所哲、中西守、平嶋尚英
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-18370064
[Presentation] 人工エクソサイトーシス系の開発2008
- Author(s)
  笹井雅夫、田所哲、平嶋尚英
- Organizer
  日本生物物理学会第46回年会
- Place of Presentation
  福岡
- Year and Date
  2008-12-04
- Data Source
  KAKENHI-PROJECT-18370064
[Presentation] アクティブゾーンタンパク質ELKSによるマスト細胞の脱顆粒制御とそのメカニズム2008
- Author(s)
  野村英宏、大塚稔久、田所哲, 平嶋尚英
- Organizer
  第31回日本分子生物学会年会、第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-18370064
[Presentation] Involvement of ELKS, an active zone protein, in exocytotic release in mast cells2008
- Author(s)
  H. Nomura, T. Ohtsuka, S. Tadokoro, M. Tanaka, N. Hirashima
- Organizer
  47th The American Society for Cell Biology Annual Meeting
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2008-12-15
- Data Source
  KAKENHI-PROJECT-18370064
[Presentation] マスト細胞の脱顆粒におけるcomplexin IIの制御機構2007
- Author(s)
  田所哲, 中西守, 平嶋尚英
- Organizer
  日本生物物理学会第45回年会
- Place of Presentation
  横浜
- Year and Date
  2007-12-22
- Data Source
  KAKENHI-PROJECT-18370064
[Presentation] Mem brane Fusion between Liposomes Containing SNARE Proteins involved in Exocytosis of Mast Cells2007
- Author(s)
  S. Tadokoro, H.Sakiyama, M. Sasai, M. Nakanishi, N. Hirashima
- Organizer
  47th The American Society for Cell Biology Annual Meeting
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-18370064
[Presentation] リポソーム再構成系によるマスト細胞の脱顆粒機構の解析2007
- Author(s)
  田所哲, 崎山裕紀, 中西守, 平嶋尚英
- Organizer
  日本薬学会第127年会
- Place of Presentation
  富山
- Year and Date
  2007-03-29
- Data Source
  KAKENHI-PROJECT-18370064
[Presentation] マスト細胞の脱顆粒に関与するSNARE調節分子による分泌制御機構2007
- Author(s)
  田所哲, 中西守, 平嶋尚英
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-18370064
[Presentation] マスト細胞における分泌小胞の開口放出部位への繋留機構
- Author(s)
  田所哲
- Organizer
  日本薬学会第１３３年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23770181
[Presentation] Enhancement effect of synaptotagmin II on SNARE mediated membrane fusion requires Ca2+ and phosphatidylserine.
- Author(s)
  Satoshi Tadokoro
- Organizer
  2012 The American Society for Cell Biology Annual Meeting
- Place of Presentation
  サンフランシスコ
- Data Source
  KAKENHI-PROJECT-23770181
[Presentation] 正電荷リポソームがマスト細胞の活性化に及ぼす影響
- Author(s)
  伊納義和、田所　哲、田邊宏樹、井上　誠、平嶋尚英、古野忠秀、中西　守
- Organizer
  第35回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  東京大学
- Data Source
  KAKENHI-PROJECT-25840051
[Presentation] 改変好塩基球を用いたがん細胞を標的とするDDSの構築
- Author(s)
  宮地克真、児玉卓也、田所　哲、平嶋尚英
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25840051
[Presentation] PIP2はsynaptotagmin 2によるSNAREを介した膜融合の促進に関与する
- Author(s)
  田所　哲、伊納義和、中西　守、平嶋尚英
- Organizer
  第50回日本生物物理学会
- Place of Presentation
  京都国際会館
- Data Source
  KAKENHI-PROJECT-25840051
[Presentation] マスト細胞の開口放出様の膜融合におけるカルシウムの役割
- Author(s)
  田所　哲
- Organizer
  第５０回日本生物物理学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23770181
[Presentation] Synaptotagmin 2 promotes SNARE-mediated membrane fusion between liposomes that mimic mast cell exocytosis depending on Ca2+ and phosphatidylinositol 4,5-bisphosphate
- Author(s)
  Satoshi Tadokoro, Yoshikazu Inoh, Mamoru Nakanishi, Naohide Hirashima
- Organizer
  2013 American Society for Cell Biology Annual Meeting
- Place of Presentation
  ニューオーリンズ
- Data Source
  KAKENHI-PROJECT-25840051
[Presentation] 人工開口放出系を用いた開口放出様膜融合の脂質依存性
- Author(s)
  田所　哲、笹井雅夫、平嶋尚英
- Organizer
  日本薬学会第１３４年回
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25840051
[]

1. HIRASHIMA Naohide (10192296)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. TANAKA Masahiko (60267953)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 中西守 (90090472)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
4. 古野忠秀 (80254308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 平嶋尚秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 14 results

TADOKORO Satoshi 田所 哲

Research Projects

Research Products

Co-Researchers

抗アレルギー活性を有するIgE標的デコイリポソーム製剤の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

単一巨大リポソームによる開口放出様の膜融合の可視化解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Interfacial analysis using artificial exo/endocytotic systems and development of target-specific secretion/uptake systemsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Stimulation-secretion coupling of artificial secretory cells using cell-sized proteoliposomesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The formation and function of mobile active zone in exocytosis from non-excitable secretory cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Effect of Complexin II on Membrane Fusion between Liposomes Containing Mast Cell SNARE Proteins2016

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Effects of PIP2 on membrane fusion between mast cell SNARE liposomes mediated by synaptotagmin22015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 巨大リポソームによるエンド／エクソサイトーシス系のモデル開発2013

Author(s)

Journal Title

NAID

Data Source

[Journal Article] 巨大リポソームによるエンド/絵くそサイトーシス系のモデル開発2013

Author(s)

Journal Title

Data Source

[Journal Article] Inhibitory effects of a cationic liposome on allergic reaction mediated by mast cell activation.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Detection of asymmetric distribution of phospholipids by fluorescence resonance energy transfer.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The suppression of IgE-mediated histamine release from mast cells following exocytic exclusion of biodegradable polymeric nanoparticles.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Endocytosis-like uptake of surface-modified drug nano-carriers into giant unilamellar vesicles.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of synaptotagmin II on membrane fusion of liposomes containing SNARE proteins involved in exocytosis in mast cells2011

Author(s)

Journal Title

DOI

TADOKORO Satoshi 田所哲