Sheng Guojun ＳｈｅｎｇＧｕｏｊｕｎ

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SHENG Guo jun シェンゴージュン

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Researcher Number	20399439
Other IDs
Affiliation (Current)	2025: 熊本大学, 国際先端医学研究機構, 特別招聘教授
Affiliation (based on the past Project Information) *help	2018 – 2024: 熊本大学, 国際先端医学研究機構, 特別招聘教授 2017: 熊本大学, 国際先端医学研究機構, 教授
Review Section/Research Field	Principal Investigator Basic Section 44020:Developmental biology-related Except Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 44020:Developmental biology-related / Orthopaedic surgery
Keywords	Principal Investigator EMT / chicken / Embryo / hemangioblast / NPAS4L / ETV2 / vasculogenesis / hematopoiesis / hemagioblast / Chicken … More / Placenta / Allantois / Chorion / Mesothelium / chiken / chorioallantois / mesoderm / chorioallantoic membrane / cancer / allantois / chorion / mesothelium … More Except Principal Investigator 血小板 / 腫瘍線維化 / CTC / 胃がん / 血行性転移 / 循環腫瘍細胞 / シェアストレス / CAFs / 腫瘍間質 / EMT / 3D genome architecture / リポーター細胞 / スクレラキシス / 中胚葉誘導 / 腱誘導 / iPS細胞 / Tendon Progenitor Cells / syndetome / mesoderm differentiation / tendon progenitor cells / Mesoderm Differentiation / iPSCs / Tendon Progenitor Cell Less

3D Genome Architecture of Epithelial Plasticity Across Species
- Principal Investigator
  
  HUANG Ruby
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Kumamoto University
腫瘍間質に依存したシェアストレス抵抗性の獲得と血行性がん転移機構の解明
- Principal Investigator
  
  石本崇胤
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Japanese Foundation for Cancer Research
Regulation of hemangioblst development by partial Epithelial Mesenchymal TransitionPrincipal Investigator
- Principal Investigator
  
  Sheng Guojun
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Kumamoto University
Molecular regulation of mesothelial EMT in avian chorioallantoic fusionPrincipal Investigator
- Principal Investigator
  
  Sheng Guojun
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Kumamoto University
Induction of tendon/ligament progenitor cells from human iPSCs
- Principal Investigator
  
  ALEV CANTAS
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto University

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Twenty years of EMT: A state of the field from TEMTIA X2024
- Author(s)
  Savagner P, Brabletz T, Cheng C, Gilles C, Hong T, Polette M, Sheng G, Stemmler MP, Thompson EW.
- Journal Title
  
  Cells Tissues Organs
  
  Volume: 1-7 Issue: 4 Pages: 38194935-38194935
- DOI
  10.1159/000536096
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02490
[Journal Article] How studies in developmental epithelial-mesenchymal transition and mesenchymal-epithelial transition inspired new research paradigms in biomedicine2024
- Author(s)
  Thiery JP, Sheng G, Shu X, Runyan R.
- Journal Title
  
  Developmen
  
  Volume: 151 Issue: 3 Pages: 38300897-38300897
- DOI
  10.1242/dev.200128
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02490
[Journal Article] ETV2 induces endothelial, but not hematopoietic, lineage specification in birds2024
- Author(s)
  Weng W, Deng Y, Deviatiiarov R, Hamidi S, Kajikawa E, Gusev O, Kiyonari H, Zhang G, Sheng G.
- Journal Title
  
  Life Sci Alliance
  
  Volume: 7 Issue: 6 Pages: 38570190-38570190
- DOI
  10.26508/lsa.202402694
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02490
[Journal Article] Dosage compensation of Z sex chromosome genes in avian fibroblast cells2023
- Author(s)
  Deviatiiarov Ruslan、Nagai Hiroki、Ismagulov Galym、Stupina Anastasia、Wada Kazuhiro、Ide Shinji、Toji Noriyuki、Zhang Heng、Sukparangsi Woranop、Intarapat Sittipon、Gusev Oleg、Sheng Guojun
- Journal Title
  
  Genome Biology
  
  Volume: 24 Issue: 1 Pages: 213-213
- DOI
  10.1186/s13059-023-03055-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18265, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-23K21302, KAKENHI-PROJECT-21H02490
[Journal Article] Developmental biology in China (Part 1)2022
- Author(s)
  Sheng Guojun、Ding Yu‐Qiang
- Journal Title
  
  Development, Growth & Differentiation
  
  Volume: 64 Issue: 2 Pages: 86-87
- DOI
  10.1111/dgd.12775
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02490
[Journal Article] Mesothelial fusion mediates chorioallantoic membrane formation2022
- Author(s)
  Nagai Hiroki、Tanoue Yuki、Nakamura Tomonori、Chan Christopher J. J.、Yamada Shigehito、Saitou Mitinori、Fukuda Takaichi、Sheng Guojun
- Journal Title
  
  Philosophical Transactions of the Royal Society B: Biological Sciences
  
  Volume: 377 Issue: 1865 Pages: 20210263-20210263
- DOI
  10.1098/rstb.2021.0263
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-20H05760, KAKENHI-PROJECT-21H02490
[Journal Article] Extraembryonic tissues: exploring concepts, definitions and functions across the animal kingdom2022
- Author(s)
  Guojun Sheng, Thorsten E Boroviak, Urs Schmidt-Ott, Shankar Srinivas
- Journal Title
  
  Biological sciences
  
  Volume: 377 Issue: 1865 Pages: 20210250-20210250
- DOI
  10.1098/rstb.2021.0250
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02490
[Journal Article] HMGN3 represses transcription of epithelial regulators to promote migration of cholangiocarcinoma in a SNAI2-dependent manner2022
- Author(s)
  Supannika Sorin, Sho Kubota, Sofiane Hamidi, Takako Yokomizo-Nakano, Kulthida Vaeteewoottacharn, Sopit Wongkham, Sakda Waraasawapati, Chawalit Pairojkul, Jie Bai, Mariko Morii, Guojun Sheng, Kanlayanee Sawanyawisuth, Goro Sashida
- Journal Title
  
  The FASEB Journal
  
  Volume: 36 Issue: 7
- DOI
  10.1096/fj.202200386r
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08421, KAKENHI-PROJECT-21H02490, KAKENHI-PROJECT-21H02952
[Journal Article] Epithelial?Mesenchymal Transition in Liver Fluke-Induced Cholangiocarcinoma2021
- Author(s)
  Sawanyawisuth Kanlayanee、Sashida Goro、Sheng Guojun
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 4 Pages: 791-791
- DOI
  10.3390/cancers13040791
- Data Source
  KAKENHI-PROJECT-18H02452, KAKENHI-PROJECT-21H02490
[Journal Article] Defining epithelial-mesenchymal transitions in animal development2021
- Author(s)
  Sheng Guojun
- Journal Title
  
  Development
  
  Volume: 148 Issue: 8 Pages: 1-6
- DOI
  10.1242/dev.198036
- Data Source
  KAKENHI-PROJECT-18H02452, KAKENHI-PROJECT-21H02490
[Journal Article] Inaugural Young Investigator Issue for Cells Tissues Organs2021
- Author(s)
  Gilbert Ryan J.、Sheng Guojun、Viebahn Christoph、Liebau Stefan、Marra Kacey G.、De Bartolo Loredana
- Journal Title
  
  Cells Tissues Organs
  
  Volume: 211 Issue: 6 Pages: 1-3
- DOI
  10.1159/000518410
- Data Source
  KAKENHI-PROJECT-21H02490
[Journal Article] Epithelial-Mesenchymal Transition Drives Three-Dimensional Morphogenesis in Mammalian Early Development2021
- Author(s)
  Ismagulov Galym、Hamidi Sofiane、Sheng Guojun
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 9
- DOI
  10.3389/fcell.2021.639244
- Data Source
  KAKENHI-PROJECT-18H02452
[Journal Article] The primitive streak and cellular principles of building an amniote body through gastrulation2021
- Author(s)
  Sheng Guojun、Martinez Arias Alfonso、Sutherland Ann
- Journal Title
  
  Science
  
  Volume: 374 Issue: 6572 Pages: 1-11
- DOI
  10.1126/science.abg1727
- Data Source
  KAKENHI-PROJECT-21H02490
[Journal Article] Twenty Years on for The Epithelial-Mesenchymal Transition International Association (TEMTIA): An Interview with Co-Founders Erik Thompson and Donald Newgreen2021
- Author(s)
  Sheng Guojun、Thompson Erik、Newgreen Donald、Denker Hans-Werner
- Journal Title
  
  Cells Tissues Organs
  
  Volume: 211 Issue: 2 Pages: 252-260
- DOI
  10.1159/000518250
- Data Source
  KAKENHI-PROJECT-21H02490
[Journal Article] Special Issue: Epithelial-Mesenchymal Transition 20202021
- Author(s)
  Thompson Erik W.、Sheng Guojun
- Journal Title
  
  Cells Tissues Organs
  
  Volume: 211 Issue: 2 Pages: 89-90
- DOI
  10.1159/000518686
- Data Source
  KAKENHI-PROJECT-21H02490
[Journal Article] Japan: prize diversity, not conformity, to boost research2021
- Author(s)
  Sheng Guojun、Carninci Piero、Siomi Mikiko C.、Suda Toshio、Alev Cantas
- Journal Title
  
  Nature
  
  Volume: 599 Issue: 7884 Pages: 201-201
- DOI
  10.1038/d41586-021-03070-9
- Data Source
  KAKENHI-PROJECT-21H02490
[Journal Article] Mesenchymal-epithelial transition regulates initiation of pluripotency exit before gastrulation2020
- Author(s)
  Sofiane Hamidi, Yukiko Nakaya, Hiroki Nagai, Cantas Alev, Takeya Kasukawa, Sapna Chhabra, Ruda Lee, Hitoshi Niwa, Aryeh Warmflash, Tatsuo Shibata, Guojun Sheng
- Journal Title
  
  Development
  
  Volume: - Issue: 3 Pages: 184960-184960
- DOI
  10.1242/dev.184960
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06265, KAKENHI-PROJECT-18H02452
[Journal Article] Partial EMT/MET: An Army of One2020
- Author(s)
  Hamidi Sofiane、Nagai Hiroki、Sheng Guojun
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: - Pages: 29-33
- DOI
  10.1007/978-1-0716-0779-4_5
- ISBN
  9781071607787, 9781071607794
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02452, KAKENHI-PROJECT-18K06265
[Journal Article] NPAS4L is involved in avian hemangioblast specification2020
- Author(s)
  Wei Weng、Hiroki Nagai、Sofiane Hamidi、Guojun Sheng
- Journal Title
  
  Haematologica
  
  Volume: 105 Issue: 11 Pages: 2647-2650
- DOI
  10.3324/haematol.2019.239434
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02452, KAKENHI-PROJECT-18K06265
[Journal Article] Guidelines and definitions for research on epithelial?mesenchymal transition2020
- Author(s)
  Yang Jing、Sheng Guojun, et al.
- Journal Title
  
  Nature Reviews Molecular Cell Biology
  
  Volume: 21 Issue: 6 Pages: 341-352
- DOI
  10.1038/s41580-020-0237-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02452, KAKENHI-PROJECT-16KT0071, KAKENHI-PROJECT-20K20520, KAKENHI-PROJECT-20K21425, KAKENHI-PUBLICLY-19H04775
[Journal Article] ISM1 regulates NODAL signaling and asymmetric organ morphogenesis.2019
- Author(s)
  L. Osorio, X. Wu, L. Wang, Z. Jiang, C. Neideck, G. Sheng and Z. Zhou*
- Journal Title
  
  Journal of Cell Biology
  
  Volume: in press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02452
[Journal Article] Biomechanical regulation of EMT and epithelial morphogenesis in amniote epiblast.2019
- Author(s)
  Hamidi S, Nakaya Y, Nagai H, Alev C, Shibata T, Sheng G.
- Journal Title
  
  Physical Biology
  
  Volume: 4 Issue: 4 Pages: 041002-041011
- DOI
  10.1088/1478-3975/ab1048
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07385, KAKENHI-PROJECT-18K06265, KAKENHI-PROJECT-18H02452
[Journal Article] Epithelial-mesenchymal transition in haematopoietic stem cell development and homeostasis.2018
- Author(s)
  S. Hamidi and G. Sheng
- Journal Title
  
  Journal of Biochemistry
  
  Volume: 164 Pages: 137-144
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02452
[Journal Article] Apolipoprotein E is an HIV-1-inducible inhibitor of viral production and infectivity in macrophages2018
- Author(s)
  Siddiqui Rokeya、Suzu Shinya、Ueno Mikinori、Nasser Hesham、Koba Ryota、Bhuyan Farzana、Noyori Osamu、Hamidi Sofiane、Sheng Guojun、Yasuda-Inoue Mariko、Hishiki Takayuki、Sukegawa Sayaka、Miyagi Eri、Strebel Klaus、Matsushita Shuzo、Shimotohno Kunitada、Ariumi Yasuo
- Journal Title
  
  PLOS Pathogens
  
  Volume: 14 Issue: 11 Pages: 1007372-1007372
- DOI
  10.1371/journal.ppat.1007372
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08870, KAKENHI-PROJECT-18K08438, KAKENHI-PROJECT-18H02452, KAKENHI-PROJECT-18H02854, KAKENHI-PROJECT-18J00112
[Journal Article] Early Hematopoietic and vascular development in the chick.2018
- Author(s)
  H. Nagai, M. Shin, W. Weng, F. Nakazawa, L. M. Jakt, C. Alev and G. Sheng
- Journal Title
  
  International Journal of Developmental Biology
  
  Volume: 62 Pages: 137-144
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02452
[Journal Article] A New Beginning for Cells Tissues Organs2018
- Author(s)
  RJ Gilbert 、Sheng Guojun、Viebahn Christoph
- Journal Title
  
  Cells Tissues Organs
  
  Volume: 205 Issue: 5-6 Pages: 254-255
- DOI
  10.1159/000496633
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02452
[Presentation] Epithelial Mesenchymal Transition in Development2018
- Author(s)
  Guojun Sheng
- Organizer
  第41回日本分子生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02452
[Presentation] Epithelial Mesenchymal Transition during Chorioallantoic Membrane Fusion2018
- Author(s)
  Guojun Sheng
- Organizer
  Avian Model Systems 10 Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02452

1. ALEV CANTAS (30726477)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. WOLTJEN Knut (50589489)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. TOGUCHIDA Junya (40273502)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 池谷真 (20442923)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 永井宏樹 (80772508)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. HUANG Ruby (50867108)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 石本崇胤 (00594889)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 福田正裕 (60802113)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. NAKAYA Yukiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. HISHIKI Takayuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. WADA Kazuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 中村友紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 久保田翔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sheng Guojun Ｓｈｅｎｇ Ｇｕｏｊｕｎ

SHENG Guo jun シェン ゴージュン

Research Projects

Research Products

Co-Researchers

3D Genome Architecture of Epithelial Plasticity Across Species

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

腫瘍間質に依存したシェアストレス抵抗性の獲得と血行性がん転移機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of hemangioblst development by partial Epithelial Mesenchymal TransitionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular regulation of mesothelial EMT in avian chorioallantoic fusionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Induction of tendon/ligament progenitor cells from human iPSCs

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Twenty years of EMT: A state of the field from TEMTIA X2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] How studies in developmental epithelial-mesenchymal transition and mesenchymal-epithelial transition inspired new research paradigms in biomedicine2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ETV2 induces endothelial, but not hematopoietic, lineage specification in birds2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dosage compensation of Z sex chromosome genes in avian fibroblast cells2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Developmental biology in China (Part 1)2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mesothelial fusion mediates chorioallantoic membrane formation2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Extraembryonic tissues: exploring concepts, definitions and functions across the animal kingdom2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] HMGN3 represses transcription of epithelial regulators to promote migration of cholangiocarcinoma in a SNAI2-dependent manner2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Epithelial?Mesenchymal Transition in Liver Fluke-Induced Cholangiocarcinoma2021

Author(s)

Journal Title

DOI

Data Source

Sheng Guojun ＳｈｅｎｇＧｕｏｊｕｎ

SHENG Guo jun シェンゴージュン