Tsukiyama Tadasuke 築山忠維

… Alternative Names

TSUKIYAMA Tadasuke 築山忠維

TAKAHASHI Hidehisa 高橋秀尚

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Researcher Number	20399819
Other IDs
External Links
Affiliation (Current)	2025: 北海道大学, 医学研究院, 助教
Affiliation (based on the past Project Information) *help	2017 – 2023: 北海道大学, 医学研究院, 助教 2018: 横浜市立大学, 医学研究科, 教授 2017: 横浜市立大学, 大学院医学研究科, 教授 2016: 北海道大学, 医学研究科, 助教 2013 – 2015: 北海道大学, 医学(系)研究科(研究院), 助教 … More 2014: 北海道大学, 大学院医学研究科, 助教 2011: 北海道大学, 大学院・・医学研究科, 助教 2007 – 2009: Hokkaido University, Graduate School of Medicine, Assistant Professor 2006: 北海道大学, 大学院医学研究科, 助手 2006: 北海道大学, 大学院医学研究科, 講師 Less
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Tumor biology / Laboratory animal science Except Principal Investigator General medical chemistry / Biomedical structure and function and related fields / Pathological medical chemistry / Neurology
Keywords	Principal Investigator がん / p53 / RNF43 / Wnt / 多段階発がん / Fzd / 発がん / ユビキチン化 / リン酸化 / Ras … More / tumorigenesis / ubiquitin / Dvl / シグナル伝達 / 免疫 / 組織修復 / FGF / crosstalk / multistep tumorigenesis / がん治療 / 大腸がん / シグナルクロストーク / 恒常性 / 突然変異 / 幹細胞 / 恒常性維持 / 形態形成 / 細胞極性 / エンドサイトーシス / ユビキチン / 翻訳後修飾 / シグナル / イメージング / マウス遺伝学 / 動物実験技術 / ガン / 可視化 / in vivoイメージング / NF-κB / 生体内 / マウス … More Except Principal Investigator ユビキチン / シグナル伝達 / 転写 / ユビキチンリガーゼ / プロテアソーム / 生体分子 / プロテオーム / 蛋白質 / Parkin / TUBE / TRIM型E3 / タンパク質修飾 / タンパク質分解 / Ubiquitin ligase / Cancer / TRIM protein / Proteasome / Ubiquitin / TRIMタンパク質 / 癌 / TRIMタンパク / がん / 細胞分化 / 細胞増殖 / 細胞内シグナル伝達 / 前立腺癌 / クロマチン / 神経発生 / 細胞周期 / アンドロゲン / 癌化 / TRIMファミリー / 分子腫瘍学 / 神経変性疾患 / U-ボックス Less

多段階発がんにおけるWntシグナルからp53経路へのクロストークの解明と治療応用Principal Investigator
- Principal Investigator
  
  築山忠維
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Hokkaido University
Dissecting the molecular mechanism of Wnt receptor ubiquitination by RNF43.Principal Investigator
- Principal Investigator
  
  Tsukiyama Tadasuke
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Hokkaido University
Establishment of method for identification of ubiquitinated protein
- Principal Investigator
  
  Hatakeyama Shigetsugu
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Biomedical structure and function and related fields
- Research Institution
  Hokkaido University
The function of RNF43 in tumorigenesis and maintaining homeostasisPrincipal Investigator
- Principal Investigator
  
  Tsukiyama Tadasuke
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Hokkaido University
Regulation of signal transduction by TRIM family proteins
- Principal Investigator
  
  Hatakeyama Shigetsugu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Hokkaido University
Molecular role of RNF43 in Wnt signaling and tumorigenesisPrincipal Investigator
- Principal Investigator
  
  Tsukiyama Tadasuke
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Hokkaido University
Comprehensive analysis of TRIM type ubiquitin ligases in cell proliferation and differentiation
- Principal Investigator
  
  HATAKEYAMA Shigetsugu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Hokkaido University
Comprehensive analysis of the regulation of carcinogenesis through TRIM type ubiquitin ligases
- Principal Investigator
  
  HATAKEYAMA Shigetsugu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Hokkaido University
Establishment and application of the library for in vivo imaging in living mice.Principal Investigator
- Principal Investigator
  
  TSUKIYAMA Tadasuke
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Hokkaido University
ハイブリッド型ユビキチン化酵素による神経変性疾患の治療
- Principal Investigator
  
  HATAKEYAMA Shigetsugu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Hokkaido University
マウス生体内におけるシグナル経路のin vivoイメージングシステムの確立と応用Principal Investigator
- Principal Investigator
  
  築山忠維
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Hokkaido University
Comprehensive analysis of TRIM family ubiquitin ligases
- Principal Investigator
  
  HATAKEYAMA Shigetsugu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Hokkaido University

[Journal Article] New insights in ubiquitin-dependent Wnt receptor regulation in tumorigenesis2024
- Author(s)
  Tsukiyama Tadasuke
- Journal Title
  
  In Vitro Cellular & Developmental Biology - Animal
  
  Volume: ePub Issue: 5 Pages: 1-17
- DOI
  10.1007/s11626-024-00855-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06605
[Journal Article] Wnt/β-Catenin Signaling Stabilizes Hemidesmosomes in Keratinocytes2022
- Author(s)
  Kosumi Hideyuki、Watanabe Mika、Shinkuma Satoru、Nohara Takuma、Fujimura Yu、Tsukiyama Tadasuke、Donati Giacomo、Iwata Hiroaki、Nakamura Hideki、Ujiie Hideyuki、Natsuga Ken
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: 142 Issue: 6 Pages: 1576-1586.e2
- DOI
  10.1016/j.jid.2021.10.018
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07633
[Journal Article] Post‐translational Wnt receptor regulation: Is the fog slowly clearing?2021
- Author(s)
  Tsukiyama Tadasuke、Koo Bon‐Kyoung、Hatakeyama Shigetsugu
- Journal Title
  
  BioEssays
  
  Volume: 43 Issue: 4 Pages: 2000297-2000297
- DOI
  10.1002/bies.202000297
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07633
[Journal Article] The role of Mediator and Little Elongation Complex in transcription termination2020
- Author(s)
  Takahashi H, Ranjan A, Chen S, Suzuki H, Shibata M, Hirose T, Hirose H, Sasaki K, Abe R, Chen K, He Y, Zhang Y, Takigawa I, Tsukiyama T, Watanabe M, Fujii S, Iida M, Yamamoto J, Yamaguchi Y, Suzuki Y, Matsumoto M, Nakayama KI, Washburn P, Saraf A, Florens L, Sato S, Tomomori-Sato C, Conaway RC, Conaway JW, Hatakeyama S
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 1-20
- DOI
  10.1038/s41467-020-14849-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07633, KAKENHI-PROJECT-19K22408, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243, KAKENHI-PROJECT-17H06112, KAKENHI-PROJECT-18H02378, KAKENHI-PROJECT-16H06221, KAKENHI-PROJECT-16K07105, KAKENHI-PROJECT-16H06279, KAKENHI-PUBLICLY-19H05280, KAKENHI-PROJECT-18H02607, KAKENHI-PROJECT-20H03182, KAKENHI-PROJECT-19K22401
[Journal Article] A phospho-switch controls RNF43-mediated degradation of Wnt receptors to suppress tumorigenesis2020
- Author(s)
  Tsukiyama Tadasuke、Zou Juqi、Kim Jihoon、Ogamino Shohei、Shino Yuki、Masuda Takamasa、Merenda Alessandra、Matsumoto Masaki、Fujioka Yoichiro、Hirose Tomonori、Terai Sayuri、Takahashi Hidehisa、Ishitani Tohru、Nakayama Keiichi I.、Ohba Yusuke、Koo Bon-Kyoung、Hatakeyama Shigetsugu
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 1-16
- DOI
  10.1038/s41467-020-18257-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07633, KAKENHI-PROJECT-20K06893, KAKENHI-PROJECT-20K21386, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-19H04823, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243, KAKENHI-PUBLICLY-19H05411, KAKENHI-PUBLICLY-20H04895, KAKENHI-PROJECT-18H02378, KAKENHI-PROJECT-19H03412, KAKENHI-PROJECT-19K22401, KAKENHI-PLANNED-20H05930
[Journal Article] Brain-Derived Neurotrophic Factor Improves Limited Exercise Capacity in Mice With Heart Failure2018
- Author(s)
  Matsumoto Junichi、et al. Hatakeyama Shigetsugu、Matsumoto Masaki、Nakayama Keiichi I.、Otsuka Yutaro、Sabe Hisataka、Tsutsui Hiroyuki、Anzai Toshihisa
- Journal Title
  
  Circulation
  
  Volume: 138 Issue: 18 Pages: 2064-2066
- DOI
  10.1161/circulationaha.118.035212
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-17H05784, KAKENHI-PUBLICLY-17H05989, KAKENHI-PROJECT-18H02378, KAKENHI-PROJECT-18H02607, KAKENHI-PROJECT-18H03187, KAKENHI-PROJECT-16H06221, KAKENHI-PROJECT-17H04758, KAKENHI-PROJECT-17K19506, KAKENHI-PROJECT-17K19578
[Journal Article] Mutations in bassoon in individuals with familial and sporadic progressive supranuclear palsy-like syndrome2018
- Author(s)
  Yabe I, Yaguchi H, Kato Y, Miki Y, Takahashi H, Tanikawa S, Shirai S, Takahashi I, Kimura M, Hama Y, Matsushima M, Fujioka S, Kano T, Watanabe M, Nakagawa S, Kunieda Y, Ikeda Y, Hasegawa M, Nishihara H, Ohtsuka T, Tanaka S, Tsuboi Y, Hatakeyama S, Wakabayashi K, Sasaki H
- Journal Title
  
  Sci Rep
  
  Volume: 8 Issue: 1 Pages: 819-819
- DOI
  10.1038/s41598-018-19198-0
- NAID
  120006377499
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09663, KAKENHI-PROJECT-16K09665, KAKENHI-PROJECT-17K19506, KAKENHI-PUBLICLY-17H05560, KAKENHI-PUBLICLY-17H05741, KAKENHI-PUBLICLY-17H05989, KAKENHI-PLANNED-26117005, KAKENHI-PROJECT-15H02356, KAKENHI-PROJECT-15H04272, KAKENHI-PROJECT-15H04701, KAKENHI-PROJECT-16H06221, KAKENHI-PROJECT-18H02378, KAKENHI-PROJECT-17K19578
[Journal Article] Anti-Sez6l2 antibody, detected in a patient with immune-mediated cerebellar ataxia, inhibits complex formation of GluR1 and Sez6l22018
- Author(s)
  Yaguchi, H., Yabe, I., Takahashi, H., Watanabe, M., Nomura, T., Kano, T., Watanabe, M. and Hatakeyama, S.
- Journal Title
  
  J. Neurol.
  
  Volume: 265 Issue: 4 Pages: 962-965
- DOI
  10.1007/s00415-018-8785-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19506, KAKENHI-PUBLICLY-17H05989, KAKENHI-PROJECT-16H06221, KAKENHI-PUBLICLY-17H05784, KAKENHI-PROJECT-18H02378, KAKENHI-PROJECT-18H02607, KAKENHI-PROJECT-17K19578
[Journal Article] Loss of TRIM29 Alters Keratin Distribution to Promote Cell Invasion in Squamous Cell Carcinoma.2018
- Author(s)
  Yanagi T, Watanabe M, Hata H, Kitamura S, Imafuku K, Yanagi H, Homma A, Wang L, Takahashi H, Shimizu H, Hatakeyama S.
- Journal Title
  
  Cancer Res
  
  Volume: 78 Issue: 24 Pages: 6795-6806
- DOI
  10.1158/0008-5472.can-18-1495
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08259, KAKENHI-PUBLICLY-17H05784, KAKENHI-PUBLICLY-17H05989, KAKENHI-PROJECT-18H02378, KAKENHI-PROJECT-18H02607, KAKENHI-PROJECT-16H06221, KAKENHI-PROJECT-17K19506, KAKENHI-PROJECT-17K19578
[Journal Article] ユビキチン化酵素RNF43によるWntシグナル制御とその破綻による発がん2017
- Author(s)
  築山忠維
- Journal Title
  
  日本応用酵素協会誌
  
  Volume: 52 Pages: 27-33
- Data Source
  KAKENHI-PROJECT-16K07105
[Journal Article] Sez6l2 regulates phosphorylation of ADD and neuritogenesis2017
- Author(s)
  Yaguchi, H., Yabe, I., Takahashi, H., Watanabe, M., Nomura, T., Kano, T., Matsumoto, M., Nakayama, K.I., Watanabe, M. and Hatakeyama, S.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 494 Issue: 1-2 Pages: 234-241
- DOI
  10.1016/j.bbrc.2017.10.047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19506, KAKENHI-PROJECT-17K19578, KAKENHI-PUBLICLY-17H05989, KAKENHI-PROJECT-15H04701, KAKENHI-PROJECT-16H06221
[Journal Article] Type XVII collagen coordinates proliferation in the interfollicular epidermis.2017
- Author(s)
  Watanabe M, Natsuga K, Nishie W, Kobayashi Y, Donati G, Suzuk Si, Fujimura Y, Tsukiyama T, Ujiie H, Shinkuma S, Nakamura H, Murakami M, Ozaki M, Nagayama M, Watt F and Shimizu H
- Journal Title
  
  eLife
  
  Volume: 6:e26635 Pages: 1-24
- DOI
  10.7554/elife.26635
- NAID
  120006337772
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07105, KAKENHI-PROJECT-16K10120, KAKENHI-PROJECT-17K16317, KAKENHI-PROJECT-16H03949, KAKENHI-PROJECT-17H04022
[Journal Article] Ribophorin II is involved in the tissue factor expression mediated by phosphatidylserine-dependent antiprothrombin antibody on monocytes2016
- Author(s)
  Fujieda Y., Amengual O., Matsumoto M., Kuroki K., Takahashi H., Kono M., Kurita Y., Otomo K., Kato M., Oku K., Bohgaki T., Horita T., Yasuda S., Maenaka K., Hatakeyama S., Nakayama K.I. and Atsumi T. et al.
- Journal Title
  
  Rheumatology
  
  Volume: 印刷中 Issue: 6 Pages: 1117-1126
- DOI
  10.1093/rheumatology/kew005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-24118002, KAKENHI-PROJECT-25461466, KAKENHI-PROJECT-15H04690, KAKENHI-PROJECT-15H04701, KAKENHI-PROJECT-16H04730, KAKENHI-PROJECT-26293230, KAKENHI-PROJECT-15K09514, KAKENHI-PROJECT-15K09545
[Journal Article] The novel heart-specific RING finger protein 207 is involved in energy metabolism in cardiomyocytes.2016
- Author(s)
  Mizushima, W., Takahashi , H., Watanabe, M., Kinugawa, S., Matsushima, S., Takada, S., Yokota, T., Furihata, T., Matsumoto, J., Tsuda, M., Chiba, I., Nagashima, S., Yanagi, S., Matsumoto, M., Nakayama, K.I., Tsutsui, H. and Hatakeyama, S.
- Journal Title
  
  J. Mol. Cell. Cardiol.
  
  Volume: 100 Pages: 43-53
- DOI
  10.1016/j.yjmcc.2016.09.013
- NAID
  120006360069
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24112006, KAKENHI-PROJECT-15H04690, KAKENHI-PROJECT-15H04701, KAKENHI-PROJECT-15H04815, KAKENHI-PROJECT-16H04730, KAKENHI-PROJECT-16H06221, KAKENHI-PROJECT-26350879, KAKENHI-PROJECT-15K15058, KAKENHI-PROJECT-26750331
[Journal Article] p53 represses the transcription of snRNA genes by preventing the formation of little elongation complex2016
- Author(s)
  Anwar, D., Takahashia, H., Watanabe, M., Suzuki, M., Fukuda, S., Hatakeyama, S.
- Journal Title
  
  Biochim. Biophys. Acta-Gene Regul. Mech.
  
  Volume: 1859 Issue: 8 Pages: 975-982
- DOI
  10.1016/j.bbagrm.2016.06.001
- NAID
  120006328999
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04690, KAKENHI-PROJECT-15H04701, KAKENHI-PROJECT-16H06221, KAKENHI-PROJECT-15K15058
[Journal Article] TRIM39 negatively regulates the NFκB-mediated signaling pathway through stabilization of Cactin2016
- Author(s)
  Suzuki M, Watanabe M, Nakamaru Y, Takagi D, Takahashi H, Fukuda S, Hatakeyama S.
- Journal Title
  
  Cell Mol Life Sci.
  
  Volume: ７３ Issue: 5 Pages: 1085-1101
- DOI
  10.1007/s00018-015-2040-x
- NAID
  120005981342
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462575, KAKENHI-PROJECT-15K15058, KAKENHI-PLANNED-24112006, KAKENHI-PLANNED-24118002, KAKENHI-PROJECT-15H04690, KAKENHI-PROJECT-15H04701, KAKENHI-PROJECT-26670130
[Journal Article] The TRIM-FLMN protein TRIM45 directly interacts with RACK1 and negatively regulates PKC-mediated signaling pathway2015
- Author(s)
  Sato, T., Takahashi, H., Hatakeyama, S., Iguchi, A. and Ariga, T
- Journal Title
  
  Oncogene
  
  Volume: 34 Issue: 10 Pages: 1280-1291
- DOI
  10.1038/onc.2014.68
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24112006, KAKENHI-PROJECT-24390065, KAKENHI-PROJECT-25670134, KAKENHI-PROJECT-15H04690
[Journal Article] The E3 ubiquitin ligase TRIM23 regulates adipocyte differentiation via stabilization of the adipocyte activator PPAR gamma.2015
- Author(s)
  Watanabe, M., Takahashi, H., Saeki, Y., Ozaki, T., Itoh, S., Suzuki, M., Mizushima, W., Tanaka, K. and Hatakeyama, S.
- Journal Title
  
  eLIFE
  
  Volume: 4
- DOI
  10.7554/elife.05615
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25860201, KAKENHI-PROJECT-15K15058, KAKENHI-PLANNED-24112006, KAKENHI-PLANNED-24112008, KAKENHI-PLANNED-24118002, KAKENHI-PROJECT-15H04690, KAKENHI-PROJECT-15H04701, KAKENHI-PROJECT-26670130, KAKENHI-PROJECT-26000014
[Journal Article] TRIM29 regulates the p63-mediated pathway in cervical cancer cells.2015
- Author(s)
  Masuda, Y., Takahashi, H. and Hatakeyama, S.
- Journal Title
  
  Biochim. Biophy. Acta-Mol. Cell Res
  
  Volume: 1853 Issue: 10 Pages: 2296-2305
- DOI
  10.1016/j.bbamcr.2015.05.035
- NAID
  120005906885
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-24112006, KAKENHI-PLANNED-24118002, KAKENHI-PROJECT-15H04690, KAKENHI-PROJECT-15H04701, KAKENHI-PROJECT-26670130
[Journal Article] Molecular role of RNF43 in canonical and noncanonical Wnt signaling2015
- Author(s)
  T. Tsukiyama,et al.
- Journal Title
  
  Mol. Cell. Biol.
  
  Volume: in press Issue: 11 Pages: 2007-2023
- DOI
  10.1128/mcb.00159-15
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670184, KAKENHI-PUBLICLY-26115701, KAKENHI-PROJECT-26293041, KAKENHI-PROJECT-26860254, KAKENHI-PROJECT-15K15023, KAKENHI-PUBLICLY-15H01248, KAKENHI-PLANNED-24112006, KAKENHI-PLANNED-24118002, KAKENHI-PROJECT-15H04690, KAKENHI-PROJECT-15H04701, KAKENHI-PROJECT-25430102, KAKENHI-PROJECT-26670130
[Journal Article] TRIM29 regulates the assembly of DNA repair proteins into damaged chromatin.2015
- Author(s)
  Masuda, Y., Takahashi, H., Sato, S., Tomonori-Sato, C., Saraf, A., Washburn, M.P., Florens, L., Conaway, R.C., Conaway, J.W. and Hatakeyama, S.
- Journal Title
  
  Nature Commun.
  
  Volume: 6 Issue: 1 Pages: 7299-7299
- DOI
  10.1038/ncomms8299
- NAID
  120005647269
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24112006, KAKENHI-PLANNED-24118002, KAKENHI-PROJECT-15H04690, KAKENHI-PROJECT-15H04701, KAKENHI-PROJECT-26670130
[Journal Article] Molecular role of RNF43 in canonical and noncanonical Wnt signaling2015
- Author(s)
  Tsukiyama, T., Fukui, A., Terai, S., Fujioka, Y., Shinada, K., Takahashi, H., Yamaguchi, T.P., Ohba, Y., Hatakeyama, S.
- Journal Title
  
  Mol. Cell. Biol.
  
  Volume: 未定
- NAID
  120005672365
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390065
[Journal Article] MED26 regulates the transcription of snRNA genes through the recruitment of little elongation complex2015
- Author(s)
  Takahashi, H., Takigawa, I., Watanabe, M., Anwar, D., Shibata, M., Tomomori-Sato, C., Sato, S., Ranjan, A., Seidel, C.W., Tsukiyama, T., Mizushima, W., Hayashi, M., Ohkawa, Y., Conaway, J.W., Conaway, R.C. and Hatakeyama, S
- Journal Title
  
  Nature Commun.
  
  Volume: 5 Issue: 1 Pages: 5941-5941
- DOI
  10.1038/ncomms6941
- NAID
  120005621881
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-24112006, KAKENHI-PROJECT-24390065, KAKENHI-PROJECT-24689016, KAKENHI-PLANNED-25116010, KAKENHI-PUBLICLY-25118501, KAKENHI-PROJECT-25280079, KAKENHI-PROJECT-25430102, KAKENHI-PROJECT-25670134, KAKENHI-PROJECT-25860201, KAKENHI-PROJECT-26290064, KAKENHI-PROJECT-26670130, KAKENHI-PLANNED-24118002, KAKENHI-PROJECT-15H04701
[Journal Article] Molecular role of RNF43 in canonical and noncanonical Wnt signaling.2015
- Author(s)
  Tsukiyama T, Fukui A, Terai S, Fujioka Y, Shinada K, Takahashi H, Yamaguchi TP, Ohba Y, and Hatakeyama S
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 印刷中
- NAID
  120005672365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430102
[Journal Article] The inflammatory cytokine IL-1b is involved in bladder remodeling after bladder outlet obstruction in mice2015
- Author(s)
  Kanno, Y., Mitsui, T., Kitta, T., Moriya, K., Tsukiyama, T., Hatakeyama, S. and Nonomura, K.
- Journal Title
  
  Neurouro. Urodyn.
  
  Volume: 未定 Issue: 3 Pages: 277-381
- DOI
  10.1002/nau.22721
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390065, KAKENHI-PROJECT-25430102, KAKENHI-PROJECT-25670134, KAKENHI-PROJECT-15H04690
[Journal Article] Pathology of frontotemporal dementia with limb girdle muscular dystrophy caused by DNAJB6 mutation2014
- Author(s)
  Yabe, I., Tanino, M., Yaguchi, H., Takiyama, A., Cai, H., Kanno, H., Takahashi, I., Hayashi, Y., Watanabe, M., Takahashi, H., Hatakeyama, S., Tanaka, S. and Sasaki, H.
- Journal Title
  
  Clin. Neurol. Neurosur.
  
  Volume: 127 Pages: 10-12
- DOI
  10.1016/j.clineuro.2014.09.013
- NAID
  120005540291
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390065, KAKENHI-PROJECT-25670134, KAKENHI-PROJECT-25860201, KAKENHI-PROJECT-26310209
[Journal Article] Identification of anti-Sez6l2 antibody in a patient with cerebellar ataxia and retinopathy2013
- Author(s)
  Yaguchi H, Yabe I, Takahashi H, Okumura F, Takeuchi A, Horiuchi, K, Kan T, Kanda, A, Saito W, Matsumoto M, Nakayama KI, Hatakeyama S and Sasaki H
- Journal Title
  
  J. Neurol.
  
  Volume: 261 Issue: 1 Pages: 224-226
- DOI
  10.1007/s00415-013-7134-5
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24112006, KAKENHI-PROJECT-24390065, KAKENHI-PROJECT-24659121, KAKENHI-PROJECT-24689016, KAKENHI-PROJECT-24791823, KAKENHI-PUBLICLY-25118501, KAKENHI-PROJECT-25670134, KAKENHI-PROJECT-25893006
[Journal Article] TRIM67 protein negatively regulates Ras activity through degradation of 80K-H and indices neuritogenesis2012
- Author(s)
  Yaguchi, H., Okumura, F., Takahashi, H., Kano, T., Kameda, H., Uchigashima, M., Tanaka, S., Watanabe, M., Sasaki, H. and Hatakeyama, S.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 287 Issue: 15 Pages: 12050-12059
- DOI
  10.1074/jbc.m111.307678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390087, KAKENHI-PROJECT-22390314, KAKENHI-PROJECT-23659144, KAKENHI-PROJECT-23800001, KAKENHI-PROJECT-24659121, KAKENHI-PROJECT-24689016
[Journal Article] Ymer acts as a multufunctional regulator in NF-kB and Fas signaling pathways2012
- Author(s)
  Tsukiyama, T., et al
- Journal Title
  
  Mol.Med.
  
  Volume: (in press) Issue: 4 Pages: 587-597
- DOI
  10.2119/molmed.2011.00435
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390087, KAKENHI-PROJECT-22390314, KAKENHI-PROJECT-23659144, KAKENHI-PROJECT-24390065
[Journal Article] TRM40 promotes neddylation of IKK gamma and is downregulated in gastrointestinal cancers2011
- Author(s)
  Noguchi, K., Okumura, F., Takahashi, N., Kataoka, A., Kamiyama, T., Todo, S. and Hatakeyama, S.
- Journal Title
  
  Carcinogenesis
  
  Volume: 32 Issue: 7 Pages: 995-1004
- DOI
  10.1093/carcin/bgr068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390087, KAKENHI-PROJECT-22390314, KAKENHI-PROJECT-23659144
[Journal Article] RNF43 interacts with NEDL1 and regulates p53-mediated transcription2011
- Author(s)
  Shinada, K., Tsukiyama, T., Sho, T., Okumura, F., Asaka, M., Hatakeyama, S.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 404 Pages: 143-147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390087
[Journal Article] TRIM29 negativelyregulates p53 via inhibition of Tip602011
- Author(s)
  Sho, T., Tsukiyama, T., Sato, T., Kondo, T., Cheng, J., Saku, T., Asaka, M. and Hatakeyama, S.
- Journal Title
  
  BBA-Mol. Cell Res.
  
  Volume: 1813 Issue: 6 Pages: 1245-1253
- DOI
  10.1016/j.bbamcr.2011.03.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390087, KAKENHI-PROJECT-22390314, KAKENHI-PROJECT-23659144
[Journal Article] TRIM24 mediates ligand-dependent activation of androgen receptor and is repressed by a bromodomain-containing protein, BRD7, in prostate cancer cells2009
- Author(s)
  Kikuchi, M., Okumura, F., Tsukiyama, T., Watanabe, M., Miyajima, N., Tanaka, J., Imamura, M., Hatakeyama, S.
- Journal Title
  
  BBA-MCR.
  
  Volume: 1793 Pages: 1828-1836
- NAID
  120001804922
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390087
[Journal Article] TRIM31 interacts with p52(Shc) and inhibits Src-induced anchorage -independent growth.2009
- Author(s)
  Watanabe M, Tsukiyama T, Hatakeyama S
- Journal Title
  
  Biochem Biophys Res Commun 388(2)
  
  Pages: 422-7
- NAID
  120001896687
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700361
[Journal Article] TRIM24 mediates ligand-dependent activation of androgen receptor and is repressed by a bromodomain-containing protein, BRD7, in prostate cancer cells.2009
- Author(s)
  Kikuchi M, Okumura F, Tsukiyama T, Watanabe M, Miyajima N, Tanaka J, Imamura M, Hatakeyama S
- Journal Title
  
  Biochim Biophys Acta. 1793(12)
  
  Pages: 1828-36
- NAID
  120001804922
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700361
[Journal Article] Wnt2/2b and beta-catenin signaling are necessary and sufficient to specify lung progenitors in the foregut.2009
- Author(s)
  Goss AM, Tian Y, Tsukiyama T, Cohen ED, Zhou D, Lu MM, Yamaguchi TP, Morrisey EE
- Journal Title
  
  Developmental Cell 17(2)
  
  Pages: 290-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700361
[Journal Article] TRIM31 interacts with p52Shc and inhibits Src-induced anchorage-independent growth2009
- Author(s)
  Watanabe, M., Tsukiyama, T. and Hatakeyama, S.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 388 Pages: 422-427
- NAID
  120001896687
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390087
[Journal Article] Ubiquitin-conjugating enzyme UBE2Q2 suppresses cell proliferation and is down-regulated in recurrent head and neck cancer2009
- Author(s)
  Maeda, H., Miyajima, N., Kano, S., Tsukiyama, T., Okumura, F., Fukuda, S. and Hatakeyama, S.
- Journal Title
  
  Mol. Cancer Res.
  
  Volume: 7 Pages: 1553-1562
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390087
[Journal Article] Inhibition of NF-kappaB signaling via tyrosine phosphorylation of Ymer2009
- Author(s)
  Kameda H, Watanabe M, Bohgaki M, Tsukiyama T, Hatakeyama S
- Journal Title
  
  Biochemical and Biophysical Research Communi cations 378(4)
  
  Pages: 744-749
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700361
[Journal Article] Ubiquitin-conjugating enzyme UBE2Q2 suppresses cell proliferation and is down-regulated in recurrent head and neck cancer.2009
- Author(s)
  Maeda H, Miyajima N, Kano S, Tsukiyama T, Okumura F, Fukuda S, Hatakeyama S
- Journal Title
  
  Mol Cancer Res. 7(9)
  
  Pages: 1553-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700361
[Journal Article] Large-scale proteomic analysis of tyrosine phosphorylation induced by TCR or BCR activation reveals new signaling pathways2009
- Author(s)
  Matsumoto, M., Oyamada, K., Takahashi, H., Sato, T., Hatakeyama, S. and Nakayama, K.I.
- Journal Title
  
  Proteomics
  
  Volume: 9 Pages: 3549-3563
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390087
[Journal Article] Ro52 functionally interacts with IgG1 and regulates its quality control via the ERAD system.2008
- Author(s)
  Takahata, M., Bohgaki, M., Tsukiyama, T., Kondo T., Asaka, M. and Hatakeyama S.
- Journal Title
  
  Mol. Immunol 45(7)
  
  Pages: 2045-2054
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390079
[Journal Article] Ubiquitylation of e-COP by PIRH2 and regulation of the secretion of PSA.2008
- Author(s)
  Maruyama S, Miyajima N, Bohgaki M, Tsukiyama T, Shigemura M, Nonomura K and Hatakeyama S.
- Journal Title
  
  Mol Cell Biochem. 307(1-2)
  
  Pages: 73-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18700393
[Journal Article] Involvement of Ymer in suppression of NF-kappaB activation by regulated interaction with lysine-63-linked polyubiquitin chain2008
- Author(s)
  Bohgaki M, Tsukiyama T, Nakajima A, Maruyama S, Watanabe M, Koike T, Hatakeyama S
- Journal Title
  
  Biochimica et Biophysica Acta 1783(5)
  
  Pages: 826-837
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700361
[Journal Article] Involvement of Ymer in suppression of NF-κB activation by regulated interaction with lysine-63-linked polyubiquitin chain.2008
- Author(s)
  Bohgaki M, Tsukiyama T, Nakajima A, Maruyama S, Watanabe M, Koike T, and Hatakeyama S.
- Journal Title
  
  BBA-Molecular Cell Research (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18700393
[Journal Article] Ro52 functionally interacts with IgG1 and regulates its quality control via the ERAD system2008
- Author(s)
  Takahata M, Bohgaki M, Tsukiyama T, Kondo T. Asaka M. Hatakevama S
- Journal Title
  
  Molecullar Immunology 45(7)
  
  Pages: 2045-2054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700361
[Journal Article] Ro52 functionally interacts with IgG1 and regulates its quality control via the ERAD system.2008
- Author(s)
  Takahata, M., Bohgaki, K., Tsukiyama, T., Kondo, T., Asaka, M. and Hatakeyama, S.
- Journal Title
  
  Mol. Immuno. 45
  
  Pages: 2045-2054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18700393
[Journal Article] Ubiquitylation of s-COP by PIRH2 and regulation of the secretion of PSA.2007
- Author(s)
  Maruyama, S., Miyajima, N., Bohgaki, M., Tsukiyama, T., Shigemura, M., Nonomura, K. and Hatakevama, S.
- Journal Title
  
  Neurosci. Lett 411
  
  Pages: 228-232
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390079
[Journal Article] Ligand-dependent transcription of estrogen receptor a is mediated by the ubiquitin ligase EFP.2007
- Author(s)
  Nakajima, A., Maruyama, S., Bohgaki, M., Miyajima, N., Tsukiyama, T., Sakuragi, N. and Hatakevama, S.
- Journal Title
  
  Biochem. Biophys. Res. Commun 357
  
  Pages: 245-251
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390079
[Journal Article] Establishment of a newly improved detection system for NF-κB activity.2007
- Author(s)
  Matsuda M, Tsukiyama T, Bohgaki M, Nonomura K, Hatakeyama S. (共同筆頭著者)
- Journal Title
  
  Immunology Letters 109(2)
  
  Pages: 175-181
- NAID
  120000968115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18700393
[Journal Article] Ligand-dependent transcription of estrogen receptor alpha is mediated by the ubiquitin ligase EFP.2007
- Author(s)
  Nakajima A, Maruyama S, Bohgaki M, Miyajima N, Tsukiyama T, Sakuragi N and Hatakeyama S.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 357
  
  Pages: 245-251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18700393
[Journal Article] Establishment of a newly improved detection system for NF-κB activity.2007
- Author(s)
  Matsuda M, Tsukiyama T, Bohgaki M, Hatakeyama S
- Journal Title
  
  Immunology Letters (in press)
- NAID
  120000968115
- Data Source
  KAKENHI-PROJECT-18700393
[Journal Article] Establishment of a newly improved detection system for NF-KB activity.2007
- Author(s)
  Matsuda, M., Tsukiyama, T., Bohgaki, M., Nonomura, K. and Hatakeyama. S.
- Journal Title
  
  Immunol. Lett 109
  
  Pages: 175-181
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390079
[Journal Article] Protection of vincristine-induced neuropathy by W1dS expression and the independence of the activity of Nmnatl.2007
- Author(s)
  Watanabe, M., Tsukiyama, T. and Hatakeyama, S.
- Journal Title
  
  Neurosci.Lett 411
  
  Pages: 228-232
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390079
[Journal Article] Protection of vincristine-induced-neuropathy by by Wld(S) expression and the independence of the activity of Nmnatl.2007
- Author(s)
  Watanabe M, Tsukiyama T, Hatakeyama S
- Journal Title
  
  Neuroscience Letters 411(3)
  
  Pages: 228-232
- Data Source
  KAKENHI-PROJECT-18700393
[Journal Article] SNIP1 is a candidate modifier of the transcriptional activity of c-Myc on E box-dependent target genes.2006
- Author(s)
  Fujii M, Lyakh LA, Bracken CP, Fukuoka J, Hayakawa M, Tsukiyama T, Soll SJ, Harris M, Rocha S, Roche KC, Tominaga S, Jen J, Perkin ND, Lechleider RJ, Roberts AB
- Journal Title
  
  Molecullar Cell 24(5)
  
  Pages: 771-783
- Data Source
  KAKENHI-PROJECT-18700393
[Journal Article] Ymer acts as a multufunctional regulator in NF-kB and Fas signaling pathways
- Author(s)
  Tsukiyama, T., Matsuda-Tsukiyama, M., Bohgaki, M., Terai, S., Tanaka, S. and Hatakeyama, S.:
- Journal Title
  
  Mol. Med.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390087
[Presentation] Wnt receptor regulation and maintaining homeostasis2023
- Author(s)
  Tadasuke Tsukiyama
- Organizer
  CGE International Seminar Series 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07633
[Presentation] 代謝がWntシグナルに及ぼす影響の検討2023
- Author(s)
  築山忠維
- Organizer
  Wnt研究会
- Data Source
  KAKENHI-PROJECT-23K06605
[Presentation] Wnt受容体分解機能を失った発がん型RNF43変異体を機能回復させる試み2023
- Author(s)
  築山忠維, 畠山鎮次
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K06605
[Presentation] 発がん過程におけるWntシグナルからp53へのクロストーク2023
- Author(s)
  築山忠維, 畠山鎮次
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K06605
[Presentation] 多段階発がんにおけるRNF43遺伝子変異の意義2023
- Author(s)
  築山忠維
- Organizer
  北海道がん若手研究者交流会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07633
[Presentation] Wnt 受容体調節の破綻が多段階発がん過程で果たす複雑な役割2022
- Author(s)
  築山忠維・畠山鎮次
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07633
[Presentation] A role of RNF43 other than Wnt receptor regulation in oncogenesis (poster)2022
- Author(s)
  Tadasuke Tsukiyama
- Organizer
  Wnt 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07633
[Presentation] Wnt受容体調節の破綻が多段階発がん過程で果たす複雑な役割2022
- Author(s)
  築山忠維
- Organizer
  第59回日本生化学会北海道支部例会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07633
[Presentation] A role of RNF43 other than Wnt receptor regulation in oncogenesis (oral)2022
- Author(s)
  Tadasuke Tsukiyama
- Organizer
  Wnt 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07633
[Presentation] Wnt receptor regulation2021
- Author(s)
  築山忠維
- Organizer
  Wnt研究会2021
- Data Source
  KAKENHI-PROJECT-19K07633
[Presentation] Wnt受容体の発現調節異常と発がん機構の解明2021
- Author(s)
  築山忠維、石谷太、高橋秀尚、松本雅記、大場雄介、中山敬一、Koo Bonkyoung、畠山鎮次
- Organizer
  第94回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07633
[Presentation] 単一遺伝子変異による多段階発がんの起動と完成2020
- Author(s)
  築山忠維・石谷太・畠山鎮次
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07633
[Presentation] Wnt受容体のユビキチン化とその破綻によるがん化2019
- Author(s)
  築山忠維
- Organizer
  Wnt研究会2018-2019
- Data Source
  KAKENHI-PROJECT-16K07105
[Presentation] 幹細胞特異的ユビキチンリガーゼRNF43の遺伝子変異による多段階発がんステップの起動と完成2019
- Author(s)
  築山忠維・石谷太・畠山鎮次
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07633
[Presentation] 幹細胞特異的ユビキチンリガーゼRNF43の遺伝子変異による多段階発がんステップの起動と完成2019
- Author(s)
  築山忠維・石谷太・畠山鎮次
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07105
[Presentation] RNF43の遺伝子変異は多段階発がんステップにおいてWntとp53経路の変異を代償する2019
- Author(s)
  築山忠維・篠裕輝・寺井小百合・高橋秀尚・BK Koo・石谷太・畠山鎮次
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K07105
[Presentation] RNF43の遺伝子変異は多段階発がんステップにおいてWntとp53経路の変異を代償する2019
- Author(s)
  築山忠維・篠裕輝・寺井小百合・高橋秀尚・BK Koo・石谷太・畠山鎮次
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07633
[Presentation] 発がん型変異RNF43はリン酸化により正常ながん抑制因子へ機能回復する2018
- Author(s)
  築山忠維
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07105
[Presentation] 幹細胞特異的ユビキチンリガーゼRNF43のリン酸化によるWntシグナル調節は個体発生・恒常性維持・発がん過程に関与する2018
- Author(s)
  築山忠維
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K07105
[Presentation] -伝統的 vs 包括的- RNF43のリン酸化異常による発がんメカニズムの解明で明らかになったがん研究手法の利点と欠点2018
- Author(s)
  築山忠維
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K07105
[Presentation] RNF43によるWntシグナルの活性制御は形態形成と発がんを制御する2017
- Author(s)
  築山忠維
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07105
[Presentation] 様々な動物モデルを用いたWntシグナル調節異常による発がん機構の解析2017
- Author(s)
  築山忠維
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16K07105
[Presentation] RNF43のリン酸化によるWntシグナルの活性制御は個体の恒常性を制御する2017
- Author(s)
  築山忠維
- Organizer
  Wnt研究会2017
- Data Source
  KAKENHI-PROJECT-16K07105
[Presentation] RNF43の翻訳後修飾はWntシグナル調節のスイッチとして機能する2016
- Author(s)
  築山忠維
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-16K07105
[Presentation] カエルモデルを用いたRNF43のリン酸化によるWntシグナル調節機構の解明2016
- Author(s)
  築山忠維、福井彰雅、寺井小百合、藤岡容一郎、品田恵佐、高橋秀尚、Terry P. Yamaguchi、大場雄介、畠山鎮次
- Organizer
  2016「個体レベルでのがん研究支援活動」ワークショップ
- Place of Presentation
  琵琶湖ホテル（滋賀県･大津）
- Year and Date
  2016-02-04
- Data Source
  KAKENHI-PROJECT-25430102
[Presentation] Post-translational modification of RNF43; a molecular switch of Wnt signaling2016
- Author(s)
  Tadasuke TSUKIYAMA
- Organizer
  Wnt meeting 2016
- Place of Presentation
  ブルノ（チェコ共和国）
- Year and Date
  2016-09-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07105
[Presentation] Wntシグナルの分子スイッチ；RNF43のリン酸化による活性制御2016
- Author(s)
  築山忠維
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-16K07105
[Presentation] カエルモデルを用いたRNF43のWntシグナル調節と発がんにおける機能検討2015
- Author(s)
  築山忠維、畠山鎮次
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25430102
[Presentation] カエルモデルから明らかになったWntシグナル調節とがんにおけるRNF43の機能2015
- Author(s)
  築山忠維、福井彰雅、寺井小百合、藤岡容一郎、品田恵佐、高橋秀尚、Terry P. Yamaguchi、大場雄介、畠山鎮次
- Organizer
  日本生化学会北海道支部第52回支部例会
- Place of Presentation
  北海道大学（北海道・札幌）
- Year and Date
  2015-07-17
- Data Source
  KAKENHI-PROJECT-25430102
[Presentation] RNF43遺伝子のミスセンス変異によるWnt/βcatenin経路のポジティブフィードバックループ形成2014
- Author(s)
  築山忠維、福井彰雅、寺井小百合、藤岡容一朗、品田佳佐、大場雄介、畠山鎮次
- Organizer
  日本生化学会北海道支部第51回支部例会
- Place of Presentation
  北海道大学百年記念会館（北海道・札幌市）
- Year and Date
  2014-07-18
- Data Source
  KAKENHI-PROJECT-25430102
[Presentation] RNF43遺伝子のミスセンス変異によるWnt/βcatenin経路のポジティブフィードバックループ形成2014
- Author(s)
  築山忠維、福井彰雅、寺井小百合、藤岡容一朗、品田佳佐、Terry P. Yamaguchi、大場雄介、畠山鎮次
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県･横浜市）
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-25430102
[Presentation] RNF43のミスセンス変異はWnt/βcateninシグナルの正のフィードバックループを形成する2014
- Author(s)
  築山忠維、畠山鎮次
- Organizer
  第73回日本癌学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県･横浜市）
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-25430102
[Presentation] Functional analysis of a novel multiprotein complex containing ataxia telangiectasia group D-complementing (ATDC) gene product, TRIM292013
- Author(s)
  Masuda, Y., Takahashi, H., Matsumoto, M., Nakayama, K., Hatakeyama, S.
- Organizer
  The 35th Naito Conference: The Ubiquitin-Protesome System: from Basic Mechanisms to Pathophysiological Roles
- Place of Presentation
  シャトレーゼガトーキングダムサッポロ（札幌）
- Data Source
  KAKENHI-PROJECT-24390065
[Presentation] RNF43遺伝子変異によるがん抑制遺伝子からがん遺伝子への機能転換2013
- Author(s)
  築山忠維，福井彰雅，寺井小百合，藤岡容一朗，品田恵佐，Yamaguchi Terry，大場雄介，畠山鎮次
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（神戸）
- Data Source
  KAKENHI-PROJECT-24390065
[Presentation] がん抑制遺伝子RNF43は異なるメカニズムによってWnt/beta-catenin経路とnoncanonical Wnt経路を抑制する2013
- Author(s)
  築山忠維、畠山鎮次
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-24390065
[Presentation] Ymer functions as a multifunctional regulator in NF-kB and Fas signaling pathways.2012
- Author(s)
  Tsukiyama T., Tsukiyama M M., bohgaki M., Tanaka S., Hatakeyama, S.
- Organizer
  the 41st meeting of the Australasian Society for immunology 2011
- Place of Presentation
  Adelaide Convention Center, Adelaide
- Data Source
  KAKENHI-PROJECT-21390087
[Presentation] Human Mediator subunit Med26 plays a role in recruitment of "Little elongation complex" to small nuclear RNA genes (ポスター)2012
- Author(s)
  Hidehisa Takahashi, Joan w. Conaway, Ronald c. Conaway, Shigetsugu Hatakeyama
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場、マリンメッセ福岡 (福岡)
- Data Source
  KAKENHI-PROJECT-24390065
[Presentation] ダイオキシン受容体内因性リガンドによる前立腺がん細胞におけるアンドロゲンレセプター発言低下と増殖抑制2012
- Author(s)
  丸山覚,築山忠維,河津隆文,佐藤択矢,千葉博基,安部崇重,佐澤陽,篠原信雄,畠山鎮次,野々村克也
- Organizer
  第21回泌尿器科分子・細胞研究会
- Place of Presentation
  北海道大学医学部学友会館「フラテ」,札幌
- Data Source
  KAKENHI-PROJECT-21390087
[Presentation] RNF43はNEDLlと結合し, p53依存性の転写を調節する(ポスター)2012
- Author(s)
  築山忠雄,畠山鎮次
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌(北海道)
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-24390065
[Presentation] Med26はLittle elongation complexをリクルートすることでsmall nuclear RNA遺伝子の発現を制御する2012
- Author(s)
  高橋秀尚, 佐藤智信, Conaway, J. W., Conaway, R. C., 畠山鎮次
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場、マリンメッセ福岡 (福岡)
- Data Source
  KAKENHI-PROJECT-24390065
[Presentation] Med26はLittle elongation complexをリクルートすることでsmall nuclear RNA遺伝子の発現を制御する2012
- Author(s)
  高橋秀尚、Joan w. Conaway、Ronald c. Conaway、畠山鎮次
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場、マリンメッセ福岡 (福岡)
- Data Source
  KAKENHI-PROJECT-24390065
[Presentation] RNF43はcanonical/noncanonical Wntシグナルの両方を抑制する(ポスター)2012
- Author(s)
  Tadasuke Tsukiyama, Akimasa Fukui, Sayuri Terai, Keisuke Shinada, Shigetsugu Hatakeyama
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場、マリンメッセ福岡 (福岡)
- Data Source
  KAKENHI-PROJECT-24390065
[Presentation] TRIM29によるTRRAP/Tip60複合体の機能制御とがん化との関わり2012
- Author(s)
  桝田安志、高橋秀尚、畠山鎮次
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場、マリンメッセ福岡 (福岡)
- Data Source
  KAKENHI-PROJECT-24390065
[Presentation] Ymer functions as a multifunctional regulator in NF-kB and Fas signaling pathways2011
- Author(s)
  Tsukiyama, T., et al
- Organizer
  the 41st meeting of the Australasian Society for immunology 2011
- Place of Presentation
  Adelaide Convention Center (Australia)
- Data Source
  KAKENHI-PROJECT-21390087
[Presentation] がん抑制遺伝子としてのWnt5a2009
- Author(s)
  築山忠維
- Organizer
  九州大学COE「個体恒常性を担う細胞運命の決定とその破綻」/SSP「生体防御におけるポストゲノムサイエンス」共催シンポジウムWntシグナルの機能と抑制 : 基礎研究から再生医療、がん治療へ」
- Place of Presentation
  福岡・九州大学
- Year and Date
  2009-03-24
- Data Source
  KAKENHI-PROJECT-20700361
[Presentation] NF-κB抑制分子 Ymer トランスジェニックマウスの解析2009
- Author(s)
  築山忠維
- Organizer
  日本分子生物学会・第32回年会
- Place of Presentation
  横浜・パシフィコ横浜
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-20700361
[Presentation] 、NF-κB抑制分子Ymerトランスジェニックマウスの解析2009
- Author(s)
  築山忠維・坊垣幸・畠山鎮次
- Organizer
  日本分子生物学会・第32回年会
- Place of Presentation
  横浜・パシフィコ横浜
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-20700361
[Presentation] NF-κBシグナルを抑制するYmerトランスジェニックマウスの解析2009
- Author(s)
  築山忠維・坊垣幸・畠山鎮次
- Organizer
  平成21年度・特定領域研究「タンパク質分解」班会議
- Place of Presentation
  滋賀・長浜ロイヤルホテル
- Year and Date
  2009-12-21
- Data Source
  KAKENHI-PROJECT-20700361
[Presentation] NF-κB抑制分子 Ymer トランスジェニックマウスの解析2009
- Author(s)
  築山忠維
- Organizer
  平成21年度・特定領域研究「タンパク質分解」班会議
- Place of Presentation
  滋賀・長浜ロイヤルホテル
- Year and Date
  2009-12-21
- Data Source
  KAKENHI-PROJECT-20700361
[Presentation] NF-κB抑制分子Ymerトランスジェニックマウスの解析2008
- Author(s)
  築山忠維・松田真由子・畠山鎮次
- Organizer
  第73回日本インターフェロン・サイトカイン学会学術集会
- Place of Presentation
  札幌・北海道大学
- Year and Date
  2008-07-11
- Data Source
  KAKENHI-PROJECT-20700361
[Presentation] NF-κB抑制分子Ymerトランスジェニックマウスの解析2008
- Author(s)
  築山忠維・坊垣幸・畠山鎮次
- Organizer
  日本分子生物学会・第31回年会
- Place of Presentation
  神戸・ポートアイランド
- Data Source
  KAKENHI-PROJECT-20700361
[Presentation] NF-κB抑制分子Ymerトランスジェニックマウスの解析2008
- Author(s)
  築山忠維・坊垣幸・畠山鎮次
- Organizer
  平成20年度・特定領域研究「タンパク質分解」班会議
- Place of Presentation
  筑波・つくばグランドホテル
- Year and Date
  2008-11-26
- Data Source
  KAKENHI-PROJECT-20700361
[Presentation] 自己免疫疾患に関与するユビキチン関連分子の治療に向けた応用2008
- Author(s)
  築山忠維・坊垣幸・畠山鎮次
- Organizer
  厚生労働科学研究費補助金免疫・アレルギー疾患予防・治療研究事業「免疫疾患に対する免疫抑制療法等先端的新規治療法に関する研究」班会議
- Place of Presentation
  札幌・北海道大学
- Year and Date
  2008-12-04
- Data Source
  KAKENHI-PROJECT-20700361
[Presentation] Trim68 is required for androgen-dependent transcription and regulates prostate cancer cell growth2007
- Author(s)
  Naoto Miyajima, Satoru Maruyama, Tadasuke Tsukiyama, Katsuya Nonomura, Shigetsugu Hatakeyama
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会・合同大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-18700393
[Presentation] ユビキチンリガーゼTripartite motif protein32(TRIM32)による癌細胞増殖制御2007
- Author(s)
  加納里志、築山忠維、福田諭、畠山鎮次
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会・合同大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-18659252
[Presentation] 改良型NF-kB活性検出システムの構築2007
- Author(s)
  築山忠維、松田真由子、畠山鎮次
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会・合同大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-18390079
[Presentation] 改良型NF-κB活性検出システムの構築2007
- Author(s)
  築山忠維・松田真由子・畠山鎮次
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会・合同大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-18700393
[Presentation] TRIM68 is required for androgen-dependent transcription and regulates prostate cancer cell growth2007
- Author(s)
  Miyajima, N., Maruyama, S., Tsukiyama, T., Nonomura, K., Hatakeyama, S.
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会・合同大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-18390079
[Presentation] 改良型NF-kB活性検出システムの構築2007
- Author(s)
  築山忠維、松田真由子、畠山鎮次
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会・合同大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-18659252
[Presentation] ユビキチンリガーゼTripartite motif protein 32(Trim32)による癌細胞増殖制御2007
- Author(s)
  加納里志・築山忠維・福田諭・畠山鎮次
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会・合同大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-18700393
[Presentation] ユビキチン統合酵素E2Q2の結合タンパク質の同定と機能的解析2007
- Author(s)
  真栄田裕行、築山忠維、畠山鎮次
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会・合同大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-18659252
[Presentation] TRIM68 is required for androgen-dependent transcription and regulatesprostate cancer cell growth2007
- Author(s)
  Miyajima, N., Maruyama, S., Tsukiyama, T., Nonomura, K., Hatakeyama, S.
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会・合同大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-18659252
[Presentation] ユビキチン結合控訴酵素E2Q2の結合蛋白質タンパク質の同定と機能解析2007
- Author(s)
  真栄田裕行・築山忠維・畠山鎮次
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会・合同大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-18700393
[Presentation] ユビキチン統合酵素E2Q2の結合タンパク質の同定と機能的解析2007
- Author(s)
  真栄田裕行、築山忠維、畠山鎮次
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会・合同大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-18390079
[Presentation] ユビキチンリガーゼTripartite motif protein32(TRIM32)による癌細胞増殖制御2007
- Author(s)
  加納里志、築山忠維、福田諭、畠山鎮次
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会・合同大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-18390079
[Presentation] 胎児皮膚形成におけるWnt/beta-cateninシグナルの発現制御〜尋常性魚鱗癬モデルマウスの解析〜2007
- Author(s)
  鈴木堅太郎・山口裕史・M Villacorte・三原健一郎・武藤誠・中潟直己・築山忠維・TP Yamaguchi・加藤茂明・W Birchmeier・山田源
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会・合同大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-18700393
[Presentation] Rin; finger protein Trim32 interacts with Abl interactor protein 2 and enhances its degradation2006
- Author(s)
  Kano, S., Tsukiyama, T., Tsukiyama, T. Fukuda, S and Hatakeyama. S.
- Organizer
  20th IUBMB International Congress of BIochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390079
[Presentation] RING-finger protein R052/TRIM21 -functionally interacts with IgGl heavy chain and p97/valosin-containing protein.2006
- Author(s)
  Takahata, M., Bohgaki, M., Tsukiyama, T., Asaka, M. and Hatakeyama. S.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390079
[Presentation] A novel protein interacts with ubiquitin modifying protein A20.2006
- Author(s)
  Bohgaki, M., Tsukiyama, T. and Hatakeyama. S.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FSOBMO Congress
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390079
[Presentation] Wnt5a is a haploinsufficient tumor suppressor that cooperates with Tcfl to suppress T cell lymphomas.2006
- Author(s)
  Tsukiyama, T., Dunty, W., Hatakeyama. S., Clevers, H. and Yamaguchi, T.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390079
[Presentation] Wnt5a is a haploinsufficient tumor suppressor that cooperates with Tcfl to suppress T cell lymphomas.2006
- Author(s)
  Tsukiyama, T., et. al
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and llth FAOBMB Congress., Kyoto
- Place of Presentation
  Kyoto International Conference Hall
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390079
[Presentation] Ubiquitin-mediated regulation of coatomer protein complex, subunit epsilon by ARNIP/Pirh2.2006
- Author(s)
  Maruyama, S., Miyajima, S., Tsukiyama, T., Nonomura, K. and Hatakeyama. S.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390079
[Presentation] がん抑制遺伝子RNF43は異なるメカニズムによってWnt/beta-catenin経路とnoncanonical Wnt経路を抑制する
- Author(s)
  築山忠維
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-25430102
[Presentation] Missense mutations of RNF43 establish a positive feedback loop of Wnt/βcatenin signaling
- Author(s)
  Tadasuke Tsukiyama, Akimasa Fukui, Sayuri Terai, Yoichiro Fujioka, Keisuke Shinada, Hidehisa Takahashi, Terry P. Yamaguchi, Yusuke Ohba, and Shigetsugu Hatakeyama
- Organizer
  2015「個体レベルでのがん研究支援活動」ワークショップ
- Place of Presentation
  琵琶湖ホテル（滋賀県・大津市）
- Year and Date
  2015-02-05 – 2015-02-06
- Data Source
  KAKENHI-PROJECT-25430102
[Presentation] メディエーター複合体による転写伸長制御
- Author(s)
  高橋秀尚, 瀧川一学, 渡部昌, Delnur Anwar, 柴田美音, 佐藤チエリ, 佐藤滋生, Amol Ranjan, Chris W Seidel, 築山忠維, 林正康、大川恭行, Joan W Conaway, Ronald C Conaway, 畠山鎮次
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-11-25 – 2014-11-28
- Data Source
  KAKENHI-PROJECT-24390065
[Presentation] Med26はLittle elongation complexをリクルートすることでsmall nuclear RNA遺伝子の発現を制御する
- Author(s)
  高橋秀尚, 瀧川一学, 渡部昌, Anwar Delnur, 柴田美音, 佐藤チエリ, 佐藤滋生, Ranjan Amol, Seidel Chris, 築山忠維, 林正康, 大川恭行, Conaway Joan, Conaway Ronald, 畠山鎮次
- Organizer
  第87回日本生化学会
- Place of Presentation
  京都国際会議場（京都府・京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24390065
[Presentation] RNF43遺伝子変異によるがん抑制遺伝子からがん遺伝子への機能転換
- Author(s)
  築山忠維
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（神戸）
- Data Source
  KAKENHI-PROJECT-25430102

1. HATAKEYAMA Shigetsugu (70294973)

# of Collaborated Projects: 7 results

# of Collaborated Products: 58 results
2. TAKAHASHI Hidehisa (30423544)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. WATANABE Masashi (10632424)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. OKUMURA Fumihiko (00507212)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
5. KATO Junko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 中山啓子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 中山敬一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 矢部一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 中丸裕爾

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 高木大

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 秦洋郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 柳輝希

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tsukiyama Tadasuke 築山 忠維

TSUKIYAMA Tadasuke 築山 忠維

TAKAHASHI Hidehisa 高橋 秀尚

Research Projects

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Co-Researchers

多段階発がんにおけるWntシグナルからp53経路へのクロストークの解明と治療応用Principal Investigator

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Dissecting the molecular mechanism of Wnt receptor ubiquitination by RNF43.Principal Investigator

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Establishment of method for identification of ubiquitinated protein

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The function of RNF43 in tumorigenesis and maintaining homeostasisPrincipal Investigator

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Regulation of signal transduction by TRIM family proteins

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Molecular role of RNF43 in Wnt signaling and tumorigenesisPrincipal Investigator

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Comprehensive analysis of TRIM type ubiquitin ligases in cell proliferation and differentiation

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Comprehensive analysis of the regulation of carcinogenesis through TRIM type ubiquitin ligases

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Establishment and application of the library for in vivo imaging in living mice.Principal Investigator

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ハイブリッド型ユビキチン化酵素による神経変性疾患の治療

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マウス生体内におけるシグナル経路のin vivoイメージングシステムの確立と応用Principal Investigator

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Comprehensive analysis of TRIM family ubiquitin ligases

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[Journal Article] New insights in ubiquitin-dependent Wnt receptor regulation in tumorigenesis2024

Author(s)

Tsukiyama Tadasuke 築山忠維

TSUKIYAMA Tadasuke 築山忠維

TAKAHASHI Hidehisa 高橋秀尚