DAN Takeuchi 竹内男

Researcher Number	20400822
Affiliation (based on the past Project Information) *help	2007 – 2012: Chiba University, 医学部附属病院, 助教 2007 – 2008: Chiba University, Chiba University Hospital, Research Associate 2007: Chiba University, Universty Hospital, Assistant Professor 2007: 千葉大学, 医学部付属病院, 助教 2006: 千葉大学, 医学部附属病院, 助手
Review Section/Research Field	Principal Investigator Digestive surgery Except Principal Investigator Digestive surgery / General surgery
Keywords	Principal Investigator 免疫学 / 移植・再生医療 / 感染症 / 肝臓外科学 / Cell Culture / Shear Stress / Infection / Immunology / Regenerative Medicine / Transplantation … More / 細胞・組織 / シアー・ストレス / 遺伝子多型 / マイクロアレイ / シグナル伝達 / 外科 … More Except Principal Investigator 脂肪肝 / 肝再生 / 臓器不全 / pancreatic cancer / knockdown / protein / cancer / proteome / 発現制御 / 膵臓癌 / 発現抑制 / 蛋白質 / 癌 / プロテオーム / 肝切除 / メタボリック・シンドローム / 再灌流障害 / 生体肝移植 / adipocytokine / メタボリックシンドローム / 阻血再灌流障害 / 肝不全 / リン酸化シグナル / 生体部分肝移植 / メタボローム解析 / プロテオーム解析 / 術後感染症 / 外科総論 / 遺伝子導入 / サイトカイン / 感染症 / 敗血症 / 障害肝 / 微小循環障害 / アポトーシス / 転写因子 / 阻血再灌流 / 胆道外科学 Less

遺伝子発現、遺伝子多型からみた肝胆道領域高度侵襲手術後の感染制御の研究Principal Investigator
- Principal Investigator
  
  竹内男
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Chiba University
A new perspective for extending use of steatotic liver graft by analyzing for phosphorylation signaling pathway and applying for endothelial progenitor cells.
- Principal Investigator
  
  YOSHIDOME Hiroyuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Chiba University
Evaluation of immune cell functions in patients with postoperative complications using proteome and metabolome analysis.
- Principal Investigator
  
  KIMURA Fumio
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Chiba University
Promotion of Liver Regeneration and Control of Infectious Complications after Liver Transplantation and Major Hepatectomy.Principal Investigator
- Principal Investigator
  
  TAKEUCHI Dan
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Chiba University
Mechanistic investigation for hepatic schemia/reperfusion injury and promising modality of prevention for organ failure
- Principal Investigator
  
  HIROYUKI Yoshidome
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Chiba University
Proteomicsによる胆道・膵癌新規抗癌剤耐性因子の解明と臨床応用の可能性
- Principal Investigator
  
  MASARU Miyazaki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Chiba University
Regulation of organ dysfunction and infectious complications after liver transplantation : in the view of innate immunity and the Kupffer cellsPrincipal Investigator
- Principal Investigator
  
  TAKEUCHI Dan
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Chiba University
Identification of specific pancreatic serum protein marker for early diagnosis by using ProteinChip technology
- Principal Investigator
  
  NOZAWA Satoshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Chiba University

All 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] CXCR4/CXCL12 expression profile is associated with tumor microenvironment and clinical outcome of liver metastases of colorectal cancer2012
- Author(s)
  Sakai N, Yoshidome H, Kimura F, Takeuchi D, Miyazaki M, et al
- Journal Title
  
  Clin Exp Metastasis
  
  Volume: 29 Pages: 101-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591500
[Journal Article] Treatment strategy for hepatocellular carcinoma with major portal vein or inferior vena cava invasion: a single institution experience2011
- Author(s)
  Yoshidome H, Takeuchi D, Kimura F, Miyazaki M, et al
- Journal Title
  
  J Am Coll Surg
  
  Volume: 212 Pages: 796-803
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591500
[Journal Article] Hepatocyte apoptosis is enhanced after ischemia/reperfusion in the steatotic liver2011
- Author(s)
  Suzuki T, Yoshidome H, Kimura F, Takeuchi D, Miyazaki M, et al
- Journal Title
  
  J Clin Biochem Nutr
  
  Volume: 48 Pages: 142-8
- NAID
  130004466631
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591500
[Journal Article] Usefulness of preoperative partial splenic embolization in hepatocellular carcinoma and hypersplenic thrombocytopenia2011
- Author(s)
  Yoshidome H, Kimura F, Takeuchi D, Miyazaki M, et al
- Journal Title
  
  Hepatogastroenterology
  
  Volume: 58 Pages: 2062-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591500
[Journal Article] Interleukin-18 exacerbates pulmonary injury after hepatic ischemia/reperfusion in mice.2010
- Author(s)
  Takeuchi D, Yoshidome H, Kurosawa H, Kimura F, Shimizu H, Ohtsuka M, Kato A, Yoshitomi H, Furukawa K, Miyazaki M.
- Journal Title
  
  J Surg res 158
  
  Pages: 87-93
- Data Source
  KAKENHI-PROJECT-20591601
[Journal Article] Hepatocyte nuclear factor-kappa beta (NF-kappaB) activation is protective but is decreased in the cholestatic liver with endotoxemia2010
- Author(s)
  Iida A, Yoshidome H, Takeuchi D, Kimura F, Miyazaki M, et al
- Journal Title
  
  Surgery
  
  Volume: 148 Pages: 477-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591500
[Journal Article] Interleukin-18 exacerbates pulmonary injury after hepaticischemia/reperfusion in mice.2010
- Author(s)
  Takeuchi D
- Journal Title
  
  Journal of Surgical Research
  
  Volume: 158 Pages: 87-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591601
[Journal Article] Interleukin-18 exacerbates pulmonary injury after hepatic ischemia/reperfusion in mice.2009
- Author(s)
  Takeuchi D
- Journal Title
  
  Journal of Surgical Research 158
  
  Pages: 87-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591601
[Journal Article] Excessive inflammation but decreased immunological response renders liver susceptible to infection in bile duct ligated mice2008
- Author(s)
  Morita Y, Yoshidome H, Kimura F, Takeuchi D, Miyazaki M, et.al.
- Journal Title
  
  J Surg Res 246
  
  Pages: 262-270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591577
[Journal Article] Cooperative role of macrophages and neutrophils in host antiprotozoan resistance in mice acutely infected with Cryptosporidium parvum.2008
- Author(s)
  Takeuchi D
- Journal Title
  
  Infection and Immunity 76
  
  Pages: 3657-3663
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591601
[Journal Article] Successful treatment for pancreatic injury presented with pancreatic ascites 2 months after a blunt abdominal trauma.2008
- Author(s)
  Takeuchi D
- Journal Title
  
  Hepatogastroenterology 55
  
  Pages: 1834-1837
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591601
[Journal Article] Excessive inflammation but decreased immunological response renders liver susceptible to infection in bile duct ligated mice2008
- Author(s)
  Morita Y, Yoshldome H, Kimura F, Takeuchi D, Miyazaki M, et. al.
- Journal Title
  
  Journal of Surgical Research (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591577
[Journal Article] Cooperative role of macrophages and neutrophils in host antiprotozoan resistance in mice acutely infected with Cryptosporidium parvum.2008
- Author(s)
  Takeuchi D, Jones VC, Kobayashi M, Suzuki F.
- Journal Title
  
  Infect Immun 76
  
  Pages: 3657-3663
- Data Source
  KAKENHI-PROJECT-20591601
[Journal Article] Excessive Inflammation but Decreased Immunological Response Renders Liver Susceptible to Infection in Bile Duct Ligated Mice2008
- Author(s)
  Morita Y, Yoshidome H, Ohtsuka M, Takeuchi D, Miyazaki M, et. al.
- Journal Title
  
  Journal of Surgical Research 146
  
  Pages: 262-270
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591500
[Journal Article] Excessive inflammation but decreased immunological response renders liver susceptible to infection in bile duct ligated mice.2008
- Author(s)
  Morita Y, Yoshidome H, Kimura F, Shimizu H, Ohtsuka M, Takeuchi D, Mitsuhashi N, Iida A, Miyazaki M.
- Journal Title
  
  J Surg Res 146
  
  Pages: 262-270
- Data Source
  KAKENHI-PROJECT-20591601
[Journal Article] Gr-1^<+>CD11b^<+> cells as an accelerator of sepsis stemming from Pseudomonas aeruginosa wound infection in thermally injured mice.2008
- Author(s)
  Kobayashi M, Yoshida T, Takeuchi D, Jones VC, Shigematsu K, Herndon DN, Suzuki F.
- Journal Title
  
  J Leukoc Biol. 83
  
  Pages: 1354-1362
- Data Source
  KAKENHI-PROJECT-20591601
[Journal Article] Successful treatment for pancreatic injury presented with pancreatic ascites 2 months after a blunt abdominal trauma.2008
- Author(s)
  Takeuchi D, Kimura F, Shimizu H, Yoshidome H, Ohtsuka M, Kato A, Yoshitomi H, Nozawa S, Suda K, Nagai M, Hanawa T, Miyazaki M.
- Journal Title
  
  Hepatogastroenterology 55
  
  Pages: 1834-1837
- Data Source
  KAKENHI-PROJECT-20591601
[Journal Article] Recent advance in the treatment of hilar cholangiocarcinoma: hepatectomy with vascular resection2007
- Author(s)
  Miyazaki M, Yoshidome H, Ohtsuka M, Kato A, Takeuchi D, et. al.
- Journal Title
  
  Journal of Hepatobiliary Pancreatic Surgery 14
  
  Pages: 463-468
- NAID
  10019811172
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591500
[Journal Article] Does prolonged Biliary obstructive jaundice sensitize the liver to endotoxemiaa
- Author(s)
  Iida A, Yoshidome H, Kimura F, Takeuchi D, Miyazaki M, et.al.
- Journal Title
  
  Shock (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591577
[Journal Article] Interlukin-18 exacerbates pulmonary injury after hepatic ischemia/reperfusion in mice
- Author(s)
  Takeuchi D, Yoshidome H, Kimura F, Miyazaki M, et.al.
- Journal Title
  
  J Surg Res (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591577
[Journal Article] Successful Treatment for Pancreatic Injury Presented with Pancreatic Ascites 2 Months after a Blunt Abdominal Trauma
- Author(s)
  Takeuchi D, Yoshidome H, Ohtsuka M, Kato A, Miyazaki M, et. al.
- Journal Title
  
  Hepatog astroenterology (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591500
[Journal Article] Successful Treatment for Pancreatic Injury Presented with Pancreatic Ascites 2 Months after a Blunt Abdominal Trauma.
- Author(s)
  Takeuchi D.
- Journal Title
  
  Hepatogastroenterology (In press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591500
[Presentation] 亜鉛含有製剤の肝切除後残肝保護効果に関する検討2012
- Author(s)
  竹内男
- Organizer
  第48回日本肝臓学会総会
- Place of Presentation
  金沢(石川)ホテル日航金沢
- Year and Date
  2012-06-08
- Data Source
  KAKENHI-PROJECT-24591996
[Presentation] 肝胆膵領域の好中球機能と合併症2010
- Author(s)
  竹内男、吉留博之、木村文夫、清水宏明、大塚将之、加藤厚、吉富秀幸、古川勝規、高屋敷吏、須田浩介、高野重紹、横山元昭、宮崎勝
- Organizer
  第110回日本外科学会定期学術集会
- Place of Presentation
  名古屋
- Year and Date
  2010-04-10
- Data Source
  KAKENHI-PROJECT-20591601
[Presentation] パネル-6消化器外科と術後感染症-周術期感染対策の温故知新-肝胆膵外科領域の術後感染発症機序の解明とImmunonutritionによる予防効果2010
- Author(s)
  木村文夫、古川勝規、清水宏明、吉留博之、大塚将之、加藤厚、吉富秀幸、竹内男、高屋敷吏、須田浩介、高野重紹、宮崎勝
- Organizer
  第65回日本消化器外科学会総会
- Place of Presentation
  下関
- Year and Date
  2010-07-14
- Data Source
  KAKENHI-PROJECT-20591512
[Presentation] 脂肪肝肝切除後の肝再生におけるリン酸化シグナルの検討2010
- Author(s)
  竹内男、吉留博之、高野重紹、木村文夫、清水宏明、大塚将之、加藤厚、吉富秀幸、古川勝規、高屋敷吏、須田浩介、宮崎勝
- Organizer
  第110回日本外科学会定期学術集会
- Place of Presentation
  名古屋
- Year and Date
  2010-04-10
- Data Source
  KAKENHI-PROJECT-20591601
[Presentation] 高度脈管侵襲(Vp3/4,Vv3)を伴う進行肝細胞癌に対する外科治療の意義2009
- Author(s)
  竹内男
- Organizer
  第64回日本消化器外科学会総会
- Place of Presentation
  大阪
- Year and Date
  2009-07-17
- Data Source
  KAKENHI-PROJECT-20591601
[Presentation] 高度脈管侵襲(Vp3/4・Vv3)を伴う進行肝細胞癌に対する外科治療の意義2009
- Author(s)
  竹内男、吉留博之、木村文夫、清水宏明、大塚将之、加藤厚、吉富秀幸、古川勝規、三橋登、宮崎勝
- Organizer
  第64回日本消化器外科学会総会
- Place of Presentation
  大阪
- Year and Date
  2009-07-17
- Data Source
  KAKENHI-PROJECT-20591601
[Presentation] 肝胆膵領域の好中球機能と合併症2009
- Author(s)
  竹内男、吉留博之、木村文夫、清水宏明、大塚将之、加藤厚、吉富秀幸、古川勝規、三橋登、高屋敷吏、須田浩介、高野重紹、横山元昭、宮崎勝
- Organizer
  第109回日本外科学会定期学術集会
- Place of Presentation
  福岡
- Year and Date
  2009-04-02
- Data Source
  KAKENHI-PROJECT-20591601
[Presentation] 軽症熱傷により誘導される感染抵抗性についての検討2008
- Author(s)
  竹内男、吉留博之、木村文夫、清水宏明、大塚将之、加藤厚、吉富秀幸、古川勝規、野沢聡志、三橋登、高屋敷吏、須田浩介、高野重紹、宮崎勝
- Organizer
  第108回日本外科学会定期学術集会
- Place of Presentation
  長崎
- Year and Date
  2008-05-15
- Data Source
  KAKENHI-PROJECT-20591601
[Presentation] Involvement of Macrophage Migration Inhibitory Factor (MIF) in Hepatic Ischemia/Reperfusion Injury2007
- Author(s)
  Takeuchi D, Yoshidome H., et. al.
- Organizer
  The 63th Annual Meeting of the Japanese Society of Gastroenterological Surgery
- Place of Presentation
  Tokyo
- Year and Date
  2007-07-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591500
[Presentation] 肝阻血再灌流障害におけるMacrophage Migration Inhibitory Factor(MIF)の関与の検討2007
- Author(s)
  竹内男, 吉留博之, 他
- Organizer
  第62回日本消化器外科学会定期学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19591577
[Presentation] 肝阻血再灌流障害におけるMacrophage Migration Inhibitory Factor (MIF) の関与の検討2007
- Author(s)
  竹内男、吉留博之、木村文夫、加藤厚、吉富秀幸、宮崎勝, 他
- Organizer
  第62回日本消化器外科学会定期学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19591577
[Presentation] 肝阻血再灌流障害におけるMacrophage Migration Inhibitory Factor(MIF)の関与の検討2007
- Author(s)
  竹内男
- Organizer
  第62回日本消化器外科学会定期学術総会
- Place of Presentation
  東京
- Year and Date
  2007-07-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591500

1. MASARU Miyazaki (70166156)

# of Collaborated Projects: 8 results

# of Collaborated Products: 22 results
2. HIROYUKI Yoshidome (10312935)

# of Collaborated Projects: 6 results

# of Collaborated Products: 23 results
3. HIDEYUKI Yoshitomi (60375631)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
4. ATSUSHI Kato (70344984)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
5. FUMIO Kimura (70334208)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
6. TAKANO Shigetsugu (20436380)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
7. OHTSUKA Masayuki (90334185)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
8. 鈴木大 (60400909)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. FURUKAWA Katsunori (00400987)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
10. NOZAWA Satoshi (30345582)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SHIMIZU Hiroaki (80272318)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 岡村大樹 (50375698)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 三浦世樹 (40456025)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 永井啓之 (50422225)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 川本潤 (90400910)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

DAN Takeuchi 竹内 男

Research Projects

Research Products

Co-Researchers

遺伝子発現、遺伝子多型からみた肝胆道領域高度侵襲手術後の感染制御の研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A new perspective for extending use of steatotic liver graft by analyzing for phosphorylation signaling pathway and applying for endothelial progenitor cells.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evaluation of immune cell functions in patients with postoperative complications using proteome and metabolome analysis.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Promotion of Liver Regeneration and Control of Infectious Complications after Liver Transplantation and Major Hepatectomy.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanistic investigation for hepatic schemia/reperfusion injury and promising modality of prevention for organ failure

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Proteomicsによる胆道・膵癌新規抗癌剤耐性因子の解明と臨床応用の可能性

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of organ dysfunction and infectious complications after liver transplantation : in the view of innate immunity and the Kupffer cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of specific pancreatic serum protein marker for early diagnosis by using ProteinChip technology

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] CXCR4/CXCL12 expression profile is associated with tumor microenvironment and clinical outcome of liver metastases of colorectal cancer2012

Author(s)

Journal Title

Data Source

[Journal Article] Treatment strategy for hepatocellular carcinoma with major portal vein or inferior vena cava invasion: a single institution experience2011

Author(s)

Journal Title

Data Source

[Journal Article] Hepatocyte apoptosis is enhanced after ischemia/reperfusion in the steatotic liver2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Usefulness of preoperative partial splenic embolization in hepatocellular carcinoma and hypersplenic thrombocytopenia2011

Author(s)

Journal Title

Data Source

[Journal Article] Interleukin-18 exacerbates pulmonary injury after hepatic ischemia/reperfusion in mice.2010

Author(s)

Journal Title

Data Source

[Journal Article] Hepatocyte nuclear factor-kappa beta (NF-kappaB) activation is protective but is decreased in the cholestatic liver with endotoxemia2010

Author(s)

Journal Title

Data Source

[Journal Article] Interleukin-18 exacerbates pulmonary injury after hepaticischemia/reperfusion in mice.2010

Author(s)

Journal Title

DAN Takeuchi 竹内男