YOSHIOKA Hideyuki 吉岡秀幸

Researcher Number	20402076
Other IDs	https://orcid.org/0000-0002-6469-7156
Affiliation (Current)	2025: 山梨大学, 大学院総合研究部, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 山梨大学, 大学院総合研究部, 准教授 2021 – 2022: 山梨大学, 大学院総合研究部, 講師 2017 – 2020: 山梨大学, 大学院総合研究部, 助教 2014 – 2016: 山梨大学, 総合研究部, 助教 2012 – 2013: 山梨大学, 医学部附属病院, 助教 2011: 山梨大学, 医学部附属病院, 診療助教 2006 – 2007: 山梨大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Neurosurgery / Basic Section 56010:Neurosurgery-related / Cerebral neurosurgery Except Principal Investigator Basic Section 56010:Neurosurgery-related / Neurosurgery / Cerebral neurosurgery
Keywords	Principal Investigator エピジェネティクス / 脳虚血耐性 / ミトコンドリア / 脳虚血 / ミトコンドリア細胞間移動 / 虚血性神経細胞障害 / 早期脳損傷 / 白質損傷 / 白質障害 / くも膜下出血 … More / エピジェネテクス / 耐性現象 / 幹細胞移植 / 脳虚血性障害 / 脳虚血耐性現象 / 虚血性神経細胞傷害 … More Except Principal Investigator ミクログリア / 虚血性神経細胞傷害 / 脳梗塞 / 虚血耐性 / 虚血性神経細胞障害 / アストロサイト / 虚血耐性現象 / 脳虚血耐性 / 診断システム / バイオマーカー / 遅発性脳虚血 / 質量分析 / 遅発性虚血性障害 / くも膜下出血 / インターフェロン制御因子ファミリー / 虚血 / RNAシークエンス / ATP / アストロサイド / グリア細胞 / micro RNA / microRNA / ischemic neuronal injury / neurogenesis / brain fatty acid bindine nrotein / 虚血性脳障害 / 虚血性神経障害 / 神経再生 / 脂肪酸結合蛋白 / 神経保護 / ischemic preconditioning / neurovascular protection / ischemic tolerance / neuroprotection / ミトコンドリアバイオジェネティクス / 脳虚血体性 / ミトコンドリアバイオジェネシス Less

質量分析装置を用いたくも膜下出血後の遅発性脳虚血に対するバイオマーカーの検討
- Principal Investigator
  
  橋本幸治
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  University of Yamanashi
脳虚血および虚血耐性現象におけるインターフェロン制御因子ファミリーの役割の解明
- Principal Investigator
  
  舘岡達
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  University of Yamanashi
脳虚血および虚血耐性現象におけるミトコンドリア細胞間移動の意義の解明Principal Investigator
- Principal Investigator
  
  吉岡秀幸
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  University of Yamanashi
New developments in the mechanism of acquisition of cerebral ischemic tolerance: intracellular molecular mechanisms and Interactions mediated by ATP receptors.
- Principal Investigator
  
  Kinouchi Hiroyuki
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  University of Yamanashi
Elucidation of mechanism of white matte injury after subarachnoid hemorrhagePrincipal Investigator
- Principal Investigator
  
  YOSHIOKA Hideyuki
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  University of Yamanashi
The roles of miRNAs in ischemic preconditioning
- Principal Investigator
  
  KINOUCHI Hiroyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  University of Yamanashi
Involvement of Nrf / ARE signaling pathway in ischemia tolerance phenomenon
- Principal Investigator
  
  YAGI Takashi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  University of Yamanashi
The role of epigenetics on preconditioning of neural stem cellsPrincipal Investigator
- Principal Investigator
  
  YOSHIOKA Hideyuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  University of Yamanashi
The roles of mitochondria biogenesis on ischemic neuronal injury and tolerance
- Principal Investigator
  
  KINOUCHI Hiroyuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  University of Yamanashi
The roles of epigenetic mechanism in cerebral ischemic preconditioningPrincipal Investigator
- Principal Investigator
  
  YOSHIOKA Hideyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  University of Yamanashi
The role offray acid binding protein (FABP) in hippocampal neurogenuesis
- Principal Investigator
  
  UCHIDA Mikito
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  University of Yamanashi

All 2023 2022 2021 2017 2016 2014 2012 Other

All Journal Article Presentation Book

[Book] Heat shock protein familyと脳虚血病態. 日本臨床最新臨床脳卒中学(上)―最新の診断と治療―2014
- Author(s)
  吉岡秀幸、木内博之
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-24592119
[Book] 脳虚血のニューロサイエンス.清水宏明編:脳神経外科診療プラクティス.脳血管障害の急性期マネージメント2014
- Author(s)
  吉岡秀幸、木内博之
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-23592088
[Book] 脳虚血のニューロサイエンス. 脳神経外科診療プラクティス１. 脳血管障害の急性期マネジメント2014
- Author(s)
  吉岡秀幸、木内博之
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-24592119
[Journal Article] STAT3 induces hypoxic preconditioning against oxidative stress in neural stem cells2023
- Author(s)
  Norito Fukuda, Hideyuki Yoshioka, Takuma Wakai, Toru Tateoka, Koji Hashimoto, Kazuya Kanemaru, Hiroyuki Kinouchi
- Journal Title
  
  Conditioning Medicine
  
  Volume: 6 Pages: 138-146
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09386
[Journal Article] Neuroprotective roles of HAX-1 in ischemic neuronal injury2021
- Author(s)
  Xin Sui, Hideyuki Yoshioka, Yuichiro Fukumoto, Kazuya Kanemaru, Hiroyuki Kinouchi
- Journal Title
  
  Experimental Neurology
  
  Volume: 339 Pages: 113642-113642
- DOI
  10.1016/j.expneurol.2021.113642
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09386
[Journal Article] Hypoxic preconditioning enhances neural stem cell transplantation therapy after intracerebral hemorrhage in mice.2016
- Author(s)
  Wakai T, Narasimhan P, Sakata H, Wang E, Yoshioka H, Kinouchi H, Chan PH.
- Journal Title
  
  J Cereb Blood Flow Metab.
  
  Volume: 36 Issue: 12 Pages: 2134-2145
- DOI
  10.1177/0271678x15613798
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05680, KAKENHI-PROJECT-26462155
[Presentation] Microglia initiated Astrocyte-Mediated Ischemic Tolerance2023
- Author(s)
  舘岡達、吉岡秀幸、若井卓馬、橋本幸治、福田憲人、小泉修一、木内博之
- Organizer
  Brain and Brain Pet 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09146
[Presentation] Microglia initiated Astrocyte-Mediated Ischemic Tolerance2023
- Author(s)
  舘岡達、吉岡秀幸、若井卓馬、橋本幸治、福田憲人、小泉修一、木内博之
- Organizer
  Brain and Brain Pet 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03769
[Presentation] アストロサイト誘導性虚血耐性現象におけるミクログリアの役割2022
- Author(s)
  舘岡達、吉岡秀幸、若井卓馬、橋本幸治、福田憲人、小泉修一、木内博之
- Organizer
  Stroke 2022
- Data Source
  KAKENHI-PROJECT-20K09386
[Presentation] アストロサイト誘導性虚血耐性現象におけるミクログリアの役割2022
- Author(s)
  舘岡達、吉岡秀幸、若井卓馬、橋本幸治、福田憲人、小泉修一、木内博之
- Organizer
  第22回日本分子脳神経外科学会
- Data Source
  KAKENHI-PROJECT-21K09146
[Presentation] アストロサイト誘導性虚血耐性現象におけるミクログリアの役割2022
- Author(s)
  舘岡達、吉岡秀幸、若井卓馬、橋本幸治、福田憲人、小泉修一、木内博之
- Organizer
  山梨神経科学研究会
- Data Source
  KAKENHI-PROJECT-21K09146
[Presentation] アストロサイト誘導性虚血耐性現象におけるミクログリアの役割2022
- Author(s)
  舘岡達、吉岡秀幸、若井卓馬、橋本幸治、福田憲人、小泉修一、木内博之
- Organizer
  Stroke 2022
- Data Source
  KAKENHI-PROJECT-19H03769
[Presentation] アストロサイト誘導性虚血耐性現象におけるミクログリアの役割2022
- Author(s)
  舘岡達、吉岡秀幸、若井卓馬、橋本幸治、福田憲人、小泉修一、木内博之
- Organizer
  第81回脳神経外科学会総会
- Data Source
  KAKENHI-PROJECT-21K09146
[Presentation] アストロサイト誘導性虚血耐性現象におけるミクログリアの役割2022
- Author(s)
  舘岡達、吉岡秀幸、若井卓馬、橋本幸治、福田憲人、小泉修一、木内博之
- Organizer
  第65回　日本脳循環代謝学会
- Data Source
  KAKENHI-PROJECT-21K09146
[Presentation] Hypoxic Preconditioning Enhances Neural Stem Cell Transplantation Therapy after Intracerebral Hemorrhage in Mice2017
- Author(s)
  Norito FUKUDA, Takuma WAKAI, Hideyuki YOSHIOKA, Pak H. CHAN, Hiroyuki KINOUCHI
- Organizer
  Brain 2019
- Place of Presentation
  ベルリン（ドイツ）
- Year and Date
  2017-04-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462155
[Presentation] マウス脳出血モデルに対するhypoxic preconditioningを併用した神経幹細胞移植治療の効果2016
- Author(s)
  若井卓馬、吉岡秀幸、八木貴、館岡達、福田憲人、金丸和也、Chan PH、木内博之
- Organizer
  第17回日本分子脳神経外科学会
- Place of Presentation
  帝京大学板橋キャンパス（東京都・板橋区）
- Year and Date
  2016-08-26
- Data Source
  KAKENHI-PROJECT-26462155
[Presentation] 脳虚血における神経細胞障害および保護機構の解明にむけて2012
- Author(s)
  木内博之、吉岡秀幸、八木貴、堀越徹
- Organizer
  山梨大学国立精神・神経医療研究センター合同シンポジウム
- Place of Presentation
  東京
- Year and Date
  2012-12-04
- Data Source
  KAKENHI-PROJECT-23592088
[Presentation] 一過性前脳虚血におけるHax-1の発現変化
- Author(s)
  吉岡秀幸、八木貴、若井卓馬、福元雄一郎、金丸和也、Pak H Chan、木内博之
- Organizer
  第26回日本脳循環代謝学会総会
- Place of Presentation
  岡山コンベンションセンター（岡山県・岡山）
- Year and Date
  2014-11-21 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-24592119
[Presentation] The Role of PARL and HtrA2 in Striatal Neuronal Injury after Transient Global Cerebral Ischemia
- Author(s)
  吉岡秀幸、嘉津政隆、坂田洋之、岡見修哉、若井卓馬、木内博之、Pak H Chan
- Organizer
  第15回日本分子脳神経外科学会
- Place of Presentation
  大手門パルズ（山形県・山形）
- Year and Date
  2014-09-14 – 2014-09-15
- Data Source
  KAKENHI-PROJECT-24592119
[Presentation] The Roles of Hax-1 after Transient Forebrain Ischemia in Mice
- Author(s)
  Hideyuki Yoshioka, Takashi Yagi, Takuma Wakai, Yuichiro Fukumoto, Kazuya Kanemaru, Pak H. Chan, Hiroyuki Kinouchi
- Organizer
  Brain 2015
- Place of Presentation
  Vancouver (Canada)
- Year and Date
  2015-06-27 – 2015-06-30
- Data Source
  KAKENHI-PROJECT-24592119

1. KINOUCHI Hiroyuki (30241623)

# of Collaborated Projects: 8 results

# of Collaborated Products: 12 results
2. YAGI Takashi (90345702)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
3. 橋本幸治 (10644792)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. UCHIDA Mikito (30313795)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 若井卓馬 (30456446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 小泉修一 (10280752)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 舘岡達 (40824595)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. 坂田洋之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. Chan Pak H.

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YOSHIOKA Hideyuki 吉岡 秀幸

Research Projects

Research Products

Co-Researchers

質量分析装置を用いたくも膜下出血後の遅発性脳虚血に対するバイオマーカーの検討

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

脳虚血および虚血耐性現象におけるインターフェロン制御因子ファミリーの役割の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

脳虚血および虚血耐性現象におけるミトコンドリア細胞間移動の意義の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

New developments in the mechanism of acquisition of cerebral ischemic tolerance: intracellular molecular mechanisms and Interactions mediated by ATP receptors.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of mechanism of white matte injury after subarachnoid hemorrhagePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The roles of miRNAs in ischemic preconditioning

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Involvement of Nrf / ARE signaling pathway in ischemia tolerance phenomenon

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of epigenetics on preconditioning of neural stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The roles of mitochondria biogenesis on ischemic neuronal injury and tolerance

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The roles of epigenetic mechanism in cerebral ischemic preconditioningPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role offray acid binding protein (FABP) in hippocampal neurogenuesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Heat shock protein familyと脳虚血病態. 日本臨床 最新臨床脳卒中学(上)―最新の診断と治療―2014

Author(s)

Publisher

Data Source

[Book] 脳虚血のニューロサイエンス.清水宏明編:脳神経外科診療プラクティス.脳血管障害の急性期マネージメント2014

Author(s)

Publisher

Data Source

[Book] 脳虚血のニューロサイエンス. 脳神経外科診療プラクティス１. 脳血管障害の急性期マネジメント2014

Author(s)

YOSHIOKA Hideyuki 吉岡秀幸

[Book] Heat shock protein familyと脳虚血病態. 日本臨床最新臨床脳卒中学(上)―最新の診断と治療―2014