SUGAUCHI FUMINAKA 菅内文中

… Alternative Names

SUGAUCHI Fuminaka 菅内文中

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Researcher Number	20405161
Affiliation (Current)	2025: 名古屋市立大学, 医薬学総合研究院(医学), 准教授
Affiliation (based on the past Project Information) *help	2011 – 2014: 名古屋市立大学, 医学(系)研究科(研究院), 研究員 2009 – 2012: Nagoya City University, 大学院・医学研究科, 研究員 2008: Nagoya City University, 大学院・医学研究科, 助教
Review Section/Research Field	Principal Investigator Gastroenterology Except Principal Investigator Gastroenterology
Keywords	Principal Investigator 複製モデル / 遺伝子変異 / B型肝炎 / 遺伝子型 / B型肝炎ウイルス / HBe抗原 / HBs抗原 / 急性肝炎 / 感染阻止 / モノクロナール抗体 … More / エスケープ変異株 / ヒト肝細胞キメラマウス / ワクチン / 再活生化 / 系統樹 / 再活性化 / コアプロモーター / recombination / Vaccine / 中和活性 / キメラマウス / ウイルス変異 / 肝癌 … More Except Principal Investigator IL28B / PEG-IFN-α治療 / IFN-λ / PEG-IFNλ治療 / PEG-IFNα治療 / IFNλ / 自然免疫応答 / インターフェロン誘導遺伝子 / 遺伝子多型 / C型肝炎ウイルス / エピゲノム / IFNラムダ / HLA-DQ / IFN ラムダ / SNP / テーラーメイド治療 / HCV / HBV遺伝子型 / HBV / キメラマウス / 薬剤耐性 / ラミブジン / エンテカビル / B型肝炎ウイルス Less

Role of IFN-Lambda for chronic hepatitis C treatment toward personalized medicine
- Principal Investigator
  
  WATANABE Tsunamasa
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Nagoya City University
ヒト肝細胞キメラマウスを用いたB型肝炎ウイルス感染制御の試みPrincipal Investigator
- Principal Investigator
  
  菅内文中
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Nagoya City University
Comprehensive analyses of IL28B genetic factor toward tailor-made therapy for chronic hepatitis C
- Principal Investigator
  
  TANAKA Yasuhito
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Nagoya City University
Mechanism of drug resistance among HBV genotypes
- Principal Investigator
  
  MIZOKAMI Masashi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Nagoya City University
A comprehensive study of recombinant hepatitis B virus genotypePrincipal Investigator
- Principal Investigator
  
  SUGAUCHI Fuminaka
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Nagoya City University

All 2013 2011 2010 2009 2008

All Journal Article Presentation

[Journal Article] Hepatitis C virus kinetics by administration of pegylated interferon-α in human and chimeric mice carrying human hepatocytes with variants of the IL28B gene.2013
- Author(s)
  Watanabe T,Sugauchi F,Tanaka Y.
- Journal Title
  
  Gut
  
  Volume: (印刷中)
- URL
  http://gut.bmj.com/content/early/2012/11/06/gutjnl-2012-302553.full.pdf+html.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390151
[Journal Article] Pretreatment Prediction of Response to Pegylated-Interferon Plus Ribavirin for Chronic Hepatitis C using Genetic Polymorphism in IL28B and Viral Factors2011
- Author(s)
  Kurosaki M, Tanaka Y, Sugauchi F.
- Journal Title
  
  J Hepatol.
  
  Volume: 54(3) Pages: 439-448
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390151
[Journal Article] Virological and clinical characteristics on reactivation of occult hepatitis B in patients with hematological malignancy.2011
- Author(s)
  Sugauchi F, Tanaka Y, Mizokami M.
- Journal Title
  
  J Med Virol.
  
  Volume: 83(3) Pages: 412-418
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390213
[Journal Article] Transmissibility of Hepatitis B Virus (HBV) Infection through Blood Transfusion from Blood Donors with Occult HBV Infection.2011
- Author(s)
  Yuen MF, Tanaka Y, Sugauchi F, Mizokami M.
- Journal Title
  
  Clin Infect Dis.
  
  Volume: 52(5) Pages: 624-632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390213
[Journal Article] Transmissibility of Hepatitis B Virus (HBV) Infection through Blood Transfusion from Blood Donors with Occult HBV Infection.2011
- Author(s)
  Yuen MF, Tanaka Y, Sugauchi F, Mizokami M. et al.
- Journal Title
  
  Clin Infect Dis 52(5)
  
  Pages: 624-632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390213
[Journal Article] Virological Characteristics of hepatitis B virus on reactivation of hepatitis B in individuals with resolved infection.2011
- Author(s)
  Sugauchi F, Mizokami M.
- Journal Title
  
  J Med Virol. 83
  
  Pages: 412-418
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590788
[Journal Article] Virological and clinical characteristics on reactivation of occult hepatitis B in patients with hematological malignancy.2011
- Author(s)
  Sugauchi F, Mizokami M.
- Journal Title
  
  J Med Virol.
  
  Volume: 83 Pages: 412-418
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590788
[Journal Article] Transmissibility of hepatitis B virus (HBV) infection through blood transfusion from blood donors with occult HBV infection.2011
- Author(s)
  Yuen MF, Sugauchi F, Mizokami M.
- Journal Title
  
  Clin Infect Dis.
  
  Volume: 52 Pages: 624-632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590788
[Journal Article] Virological and clinical characteristics on reactivation of occult hepatitis B in patients with hematological malignancy.2011
- Author(s)
  Sugauchi F, Tanaka Y, Mizokami M. et al.
- Journal Title
  
  J Med Virol 83(3)
  
  Pages: 412-418
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390213
[Journal Article] Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C2011
- Author(s)
  Tanaka Y, Sakamoto N, et al.
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 20(17) Issue: 17 Pages: 3507-3516
- DOI
  10.1093/hmg/ddr249
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226, KAKENHI-PROJECT-21390227, KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-21659186, KAKENHI-PROJECT-22390151, KAKENHI-PROJECT-22659145, KAKENHI-PROJECT-23390195, KAKENHI-PROJECT-23390201
[Journal Article] Positive selection of core 70Q variant genotype 1b hepatitis Cvirus strains induced by pegylated interferon and ribavirin.2010
- Author(s)
  Kurbanov F,Tanaka Y,Sugauchi F.
- Journal Title
  
  J Infect Dis.
  
  Volume: 201(11) Issue: 11 Pages: 1663-1671
- DOI
  10.1086/652500
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390151
[Journal Article] Reactivation of hepatitis B virus in HBsAg-negative patients with multiple myeloma : two case reports.2010
- Author(s)
  Yoshida T, Sugauchi F, Mizokami M.
- Journal Title
  
  Int J Hematol.
  
  Volume: 91 Pages: 844-849
- NAID
  10026511317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590788
[Journal Article] Positive selection of core 70Q variant genotype 1b hepatitis C virus strains induced by pegylated interferon and ribavirin.2010
- Author(s)
  Kurbanov F, Tanaka Y, Sugauchi F.
- Journal Title
  
  J Infect Dis.
  
  Volume: 201(11) Pages: 1663-1671
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390151
[Journal Article] 【性感染症への対応と治療】肝炎ウイルス2009
- Author(s)
  菅内文中
- Journal Title
  
  臨床婦人科産科 63(2)
  
  Pages: 157-161
- Data Source
  KAKENHI-PROJECT-20390213
[Journal Article] Distribution of Hepatitis B Virus Genotypes among Patients with Chronic Infection in Japan Shifting toward an Increase of Genotype A.2009
- Author(s)
  Matsuura K, Sugauchi F, Mizokami M.
- Journal Title
  
  J Clin Microbiol. 47
  
  Pages: 1476-1483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590788
[Journal Article] 【性感染症への対応と治療】肝炎ウイルス2009
- Author(s)
  菅内文中
- Journal Title
  
  臨床婦人科産科 63(2)
  
  Pages: 157-161
- Data Source
  KAKENHI-PROJECT-20590788
[Journal Article] 核酸アナログ時代からみるHBV. HBV感染症のnatural history up to data2008
- Author(s)
  菅内文中
- Journal Title
  
  肝・胆・膵 56
  
  Pages: 665-669
- Data Source
  KAKENHI-PROJECT-20590788
[Presentation] In vivo model using uPA/SCID mice with human hepatocytes to study cross-genotype protection of HBV and a roleof HBs antigen mutation in immunity escape.2010
- Author(s)
  菅内文中
- Organizer
  The 61^<st> annual meeting of the AASLD.
- Place of Presentation
  The Hynes Conventi on Center (Boston USA.)
- Data Source
  KAKENHI-PROJECT-20590788
[Presentation] IN VIVO MODEL USING UPA/SCID MICE WITH HUMAN HEPATOCYTES TO STUDY CROSS-GENOTYPE PROTECTIONS OF HBV AND A ROLE OF HBS ANTIGEN MUTATION IN IMMUNITY ESCAPE.2010
- Author(s)
  菅内文中
- Organizer
  The 61^<st> annual meeting of the AASLD
- Place of Presentation
  The Hynes Convention Center (Boston USA)
- Data Source
  KAKENHI-PROJECT-20390213
[Presentation] ヒト肝細胞キメラマウスにおけるB型肝炎ウイルス感染防御の試み2010
- Author(s)
  菅内文中、溝上雅史
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  ホテルメトロポリタン山形(山形市)
- Data Source
  KAKENHI-PROJECT-20590788
[Presentation] B型肝炎の母子および水平感染の実態とワクチン戦略:ヒト肝細胞キメラマウスにおけるB型肝炎ウイルス感染防御の試み2010
- Author(s)
  菅内文中
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  ホテルメトロポリタン山形(山形市)
- Data Source
  KAKENHI-PROJECT-20590788
[Presentation] ラミブジン投与例におけるエンテカビル切り替え無作為割り付け試験2010
- Author(s)
  松浦健太郎、菅内文中、溝上雅史
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  ホテルメトロポリタン山形(山形市)
- Data Source
  KAKENHI-PROJECT-20590788
[Presentation] GENOME-WIDE ASSOCIATION STUDY IDENTIFIES IL28B ASSOCIATED WITH RESPONSE TO PEGYLATED INTERFERON-ALFA AND RIBAVIRIN THERAPY FOR JAPANESE PATIENTS WITH CHRONIC HEPATITIS C2010
- Author(s)
  Tanaka Y, Sugauchi F.
- Organizer
  45^<th> Annual Meeting Of The European Association For The Study Of The Liver
- Place of Presentation
  Reed Messe Wien Exhibition & Congress Center (Vienna, Austria)
- Data Source
  KAKENHI-PROJECT-22390151
[Presentation] IL28B遺伝子多型はC型肝炎ウイルス自然排除に関与する2010
- Author(s)
  松浦健太郎、田中靖人、菅内文中
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  ホテルメトロポリタン山形 (山形市)
- Data Source
  KAKENHI-PROJECT-22390151
[Presentation] IDENTIFICATION OF GENETIC VARIANTS OF IL28B GENE ASSOCIATED WITH CLINICAL COURSE OF HEPATITIS C VIRUS INFECTION IN JAPANESE POPULATION2010
- Author(s)
  Matsuura K, Tanaka Y, Sugauchi F.
- Organizer
  61th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  The Hynes Convention Center (Boston, USA)
- Data Source
  KAKENHI-PROJECT-22390151
[Presentation] In vivo model using uPA/SCID mice with human hepatocytes to study cross-genotype protection of HBV and a role of HBs antigenmutation in immunity escape2010
- Author(s)
  Sugauchi F, Mizokami M.
- Organizer
  The 61^<st> annual meeting of the AASLD
- Place of Presentation
  The Hynes Convention Center (Boston USA)
- Data Source
  KAKENHI-PROJECT-20590788
[Presentation] ヒト肝細胞キメラマウスにおけるB型肝炎ウイルス感染防御の試み2010
- Author(s)
  菅内文中、田中靖人、溝上雅史
- Organizer
  第46回日本肝臓学会総
- Place of Presentation
  ホテルメトロポリタン山形 (山形市)
- Data Source
  KAKENHI-PROJECT-20390213
[Presentation] B型慢性肝炎難治例への対策B型肝炎に対するAdefovir、Entecavirの治療成績と多剤耐性HBV変異株に対するTenofovirの有効性(シンポジウム10:B型慢性肝炎難治例への対策)2009
- Author(s)
  菅内文中
- Organizer
  第13回日本肝臓学会大会
- Place of Presentation
  京都国際会館(京都市)
- Data Source
  KAKENHI-PROJECT-20590788
[Presentation] Clinical significance of a novel high-sensitivity hepatitis B surface antigen immunoassay in patients with hepatitis B virus infection2009
- Author(s)
  菅内文中
- Organizer
  60th American Association for the Study of Liver Disease(AASLD)
- Place of Presentation
  Boston MA, USA
- Data Source
  KAKENHI-PROJECT-20390213
[Presentation] Distribution of hepatitis B virus genotypes among patients with chronic infection in Japan shifting toward an increase of genotype A2009
- Author(s)
  菅内文中, 他
- Organizer
  13^<th> International Symposium on Viral Hepatitisand Liver Disease
- Place of Presentation
  ワシントンD. C
- Data Source
  KAKENHI-PROJECT-20590788
[Presentation] B型慢性肝炎難治例への対策 B型肝炎に対する Adefovir、Entecavir の治療成績と多剤耐性HBV変異株に対する Tenofovir の有効性2009
- Author(s)
  菅内文中
- Organizer
  第13回日本肝臓学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590788
[Presentation] Clinical significance of a novel high-sensitivity hepatitis B surface antigen immunoassay in patients with hepatitis B virus infection2009
- Author(s)
  菅内文中
- Organizer
  60th American Association for the Study of Liver Disease(AASLD)
- Place of Presentation
  Boston MA, USA
- Data Source
  KAKENHI-PROJECT-20590788
[Presentation] Clinical significance of a novel high-sensitivity hepatitis B surface antigen immunoassay in patients with hepatitis B virus infection.2009
- Author(s)
  菅内文中
- Organizer
  The 60^<th> American Association for the Study of Liver Disease (AASLD).
- Place of Presentation
  The Hynes Convention Center (Boston USA)
- Data Source
  KAKENHI-PROJECT-20590788
[Presentation] B型慢性肝炎難治例への対策 B型肝炎に対する Adefovir、 Entecavir の治療成績と多剤耐性HBV変異株に対する Tenofovir の有効性2009
- Author(s)
  菅内文中
- Organizer
  第13回日本肝臓学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20390213
[Presentation] B型慢性肝炎難治例への対策B型肝炎に対するAdefovir、Entecavirの治療成績と多剤耐性HBV 変異株に対するTenofovir の有効性2009
- Author(s)
  菅内文中
- Organizer
  第13回日本肝臓学会大会
- Place of Presentation
  京都国際会館(京都市)
- Data Source
  KAKENHI-PROJECT-20390213
[Presentation] B型慢性肝疾患の治療戦略エンテカビル長期投与による治療効果及び耐性変異出現パターン2008
- Author(s)
  田中靖人.菅内文中
- Organizer
  第94回日本消化器病学会総会
- Place of Presentation
  福岡サンパレスホテル&ホール(福岡市)
- Data Source
  KAKENHI-PROJECT-20590788
[Presentation] シンポジウム : 造血器悪性腫瘍治療後のHBV再活性化に対する方策2008
- Author(s)
  菅内文中, 他
- Organizer
  第12回日本肝臓学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590788
[Presentation] Influences of hepatitis B virus genotype and precore mutations on reactivation of occult hepatitis B in patients with hematological malignancy.2008
- Author(s)
  菅内文中
- Organizer
  The 59th American Association for the Study of Liver Disease (AASLD).
- Place of Presentation
  Moscone West Convention Center (San Francisco USA)
- Data Source
  KAKENHI-PROJECT-20590788
[Presentation] B型ウイルス肝炎の治療B型慢性肝炎に対するエンテカビル長期投与の有用性(ワークショップ)2008
- Author(s)
  田中靖人.菅内文中
- Organizer
  第44日本肝臓学会総会
- Place of Presentation
  愛媛県県民文化会館(松山市)
- Data Source
  KAKENHI-PROJECT-20590788
[Presentation] 造血器悪性腫瘍治療後のHBV再活性化に対する方策(シンポジウム)2008
- Author(s)
  菅内文中
- Organizer
  第12回日本肝臓学会大会
- Place of Presentation
  グランドプリンスホテル新高輪他(東京都)
- Data Source
  KAKENHI-PROJECT-20590788
[Presentation] Influences of hepatitis B virus genotype and precore mutations on reactivation of occult hepatitis B in patients with hematological malignancy.2008
- Author(s)
  菅内文中, 他
- Organizer
  59th American Association for the Study of Liver Disease (AASLD)
- Place of Presentation
  サンフランシスコ
- Data Source
  KAKENHI-PROJECT-20590788

1. MIZOKAMI Masashi (40166038)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
2. TANAKA Yasuhito (90336694)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
3. FUAT Kurbanov (10444978)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. KONDO Yutaka (00419897)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MIYOSHI Ichiro (10183972)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. FUJITA Takashi (10156870)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. WATANABE Tsunamasa (20338528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SUGAUCHI Fuminaka (23590982)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 坂本直哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SUGAUCHI FUMINAKA 菅内 文中

SUGAUCHI Fuminaka 菅内 文中

Research Projects

Research Products

Co-Researchers

Role of IFN-Lambda for chronic hepatitis C treatment toward personalized medicine

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒト肝細胞キメラマウスを用いたB型肝炎ウイルス感染制御の試みPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Comprehensive analyses of IL28B genetic factor toward tailor-made therapy for chronic hepatitis C

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of drug resistance among HBV genotypes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A comprehensive study of recombinant hepatitis B virus genotypePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Hepatitis C virus kinetics by administration of pegylated interferon-α in human and chimeric mice carrying human hepatocytes with variants of the IL28B gene.2013

Author(s)

Journal Title

URL

Data Source

[Journal Article] Pretreatment Prediction of Response to Pegylated-Interferon Plus Ribavirin for Chronic Hepatitis C using Genetic Polymorphism in IL28B and Viral Factors2011

Author(s)

Journal Title

Data Source

[Journal Article] Virological and clinical characteristics on reactivation of occult hepatitis B in patients with hematological malignancy.2011

Author(s)

Journal Title

Data Source

[Journal Article] Transmissibility of Hepatitis B Virus (HBV) Infection through Blood Transfusion from Blood Donors with Occult HBV Infection.2011

Author(s)

Journal Title

Data Source

[Journal Article] Transmissibility of Hepatitis B Virus (HBV) Infection through Blood Transfusion from Blood Donors with Occult HBV Infection.2011

Author(s)

Journal Title

Data Source

[Journal Article] Virological Characteristics of hepatitis B virus on reactivation of hepatitis B in individuals with resolved infection.2011

Author(s)

Journal Title

Data Source

[Journal Article] Virological and clinical characteristics on reactivation of occult hepatitis B in patients with hematological malignancy.2011

Author(s)

Journal Title

Data Source

[Journal Article] Transmissibility of hepatitis B virus (HBV) infection through blood transfusion from blood donors with occult HBV infection.2011

Author(s)

Journal Title

Data Source

[Journal Article] Virological and clinical characteristics on reactivation of occult hepatitis B in patients with hematological malignancy.2011

Author(s)

Journal Title

Data Source

[Journal Article] Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Positive selection of core 70Q variant genotype 1b hepatitis Cvirus strains induced by pegylated interferon and ribavirin.2010

Author(s)

Journal Title

SUGAUCHI FUMINAKA 菅内文中

SUGAUCHI Fuminaka 菅内文中