Ichikawa Tomohiro 市川朋宏

… Alternative Names

市川朋宏イチカワトモヒロ

ICHIKAWA Tomohiro 市川朋宏

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Researcher Number	20405450
Other IDs
Affiliation (Current)	2025: 東北大学, 大学病院, 講師
Affiliation (based on the past Project Information) *help	2022 – 2024: 東北大学, 大学病院, 講師 2018 – 2021: 東北大学, 大学病院, 助教 2014: 和歌山県立医科大学, 医学部, 助教 2010 – 2012: 和歌山県立医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related / Respiratory organ internal medicine
Keywords	Principal Investigator 気管支喘息 / ダニ抗原 / 上皮バリア機能 / 気道上皮 / 気道上皮細胞 / 肺線維芽細胞 / 慢性閉塞性肺疾患 / biologics / exhaled breath condesate / non type 2 … More / biomarker / Asthma / マクロファージ / オキシステロール / 好酸球 / anastrozole / マウスモデル / 27-hydroxycholsterol / PAR2 / 好中球性炎症 / nilvadipine / CYP27A1 / 27-hydroxycholesterol / E-Cadherin / tight junction protein / PGC１α / 脱アセチル化酵素 / SRT1720 / アレルゲン / PGC1alpha / ミトコンドリア / ミトコンドリア新生 / ダニ / アレルギー / ウイルス感染 / 細胞老化 / ステロイド抵抗性 / TIMP / HDAC / TGF-β1 / NF-kB / 窒素化ストレス / テオフィリン / 気道リモデリング / 難治性喘息 / リモデリング / IRF-3 / NF-κB / iNOS / MMP / 閉塞性肺疾患 Less

Research Projects
(5 results)
Research Products
(30 results)

Identification of new biomarker for non-type 2 severe asthmaPrincipal Investigator
- Principal Investigator
  
  市川朋宏
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Tohoku University
CYP27A1: A novel target for treatment of asthmaPrincipal Investigator
- Principal Investigator
  
  Ichikawa Tomohiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Tohoku University
Role of mitochondrial dysfunction in epithelial barrier disruptionPrincipal Investigator
- Principal Investigator
  
  Ichikawa Tomohiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Tohoku University
肺構成細胞の細胞老化の機序の解明～慢性閉塞性肺疾患の病態制御を目指して～Principal Investigator
- Principal Investigator
  
  市川朋宏
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Wakayama Medical University
Role of MMPs in refractory asthmaPrincipal Investigator
- Principal Investigator
  
  ICHIKAWA Tomohiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Wakayama Medical University

All 2024 2021 2019 2015 2014 2013 2012 2011 2010

All Journal Article Presentation Book

[Book] 臨床免疫・アレルギー科2015
- Author(s)
  市川朋宏
- Total Pages
  8
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-26860612
[Book] COPD 大規模臨床研究の全容2012
- Author(s)
  市川朋宏, 一ノ瀬正和
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-22790766
[Book] 日本胸部臨床2011
- Author(s)
  市川朋宏
- Total Pages
  11
- Publisher
  克誠堂出版
- Data Source
  KAKENHI-PROJECT-22790766
[Book] 日本胸部臨床2011
- Author(s)
  市川朋宏, 一ノ瀬正和
- Publisher
  克誠堂出版
- Data Source
  KAKENHI-PROJECT-22790766
[Book] アレルギー・免疫2010
- Author(s)
  市川朋宏, 杉浦久敏
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-22790766
[Book] アレルギー・免疫17巻12号2010
- Author(s)
  市川朋宏
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-22790766
[Journal Article] CYP27A1-27-hydroxycholesterol axis in the respiratory system contributes to house dust mite-induced allergic airway inflammation2024
- Author(s)
  Ito Tatsunori、Ichikawa Tomohiro、Yamada Mitsuhiro、Hashimoto Yuichiro、Fujino Naoya、Numakura Tadahisa、Sasaki Yusaku、Suzuki Ayumi、Takita Katsuya、Sano Hirohito、Kyogoku Yorihiko、Saito Takuya、Koarai Akira、Tamada Tsutomu、Sugiura Hisatoshi
- Journal Title
  
  Allergol. Int.
  
  Volume: 73 Issue: 1 Pages: 151-163
- DOI
  10.1016/j.alit.2023.08.005
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08147, KAKENHI-PROJECT-21K08148
[Journal Article] PGC-1α regulates airway epithelial barrier dysfunction induced by house dust mite2021
- Author(s)
  Tsutomu Saito, Tomohiro Ichikawa et al.
- Journal Title
  
  Respiratory Research
  
  Volume: 22 Pages: 1-16
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08166
[Journal Article] 25-hydroxycholesterol promotes fibroblast-mediated tissue remodeling through NF-κB dependent pathway.2013
- Author(s)
  Ichikawa T, Sugiura H, Koarai A, Kikuchi T, Hiramatsu M, Kawabata H, Akamatsu K, Hirano T, Nakanishi M, Matsunaga K, Minakata Y, Ichinose M.
- Journal Title
  
  Exp Cell Res
  
  Volume: 319 Pages: 1176-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790766
[Journal Article] 25-Hydroxycholesterol promotes fibroblast-mediated tissue remodeling through NF-κB dependent pathway2013
- Author(s)
  Tomohiro Ichikawa
- Journal Title
  
  Experimental Cell Research
  
  Volume: 319 Issue: 8 Pages: 1176-1186
- DOI
  10.1016/j.yexcr.2013.02.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790766, KAKENHI-PROJECT-23591126, KAKENHI-PROJECT-24591136, KAKENHI-PROJECT-25461502
[Journal Article] Associated demographics of persistent exhaled nitric oxide elevation in treated asthmatics.2012
- Author(s)
  Matsunaga K, Yanagisawa S, Hirano T, Ichikawa T, Koarai A, Akamatsu K, Sugiura H, Minakata Y, Matsunaga K, Kawayama T, Ichinose M.
- Journal Title
  
  Clin Exp Allergy
  
  Volume: 42 Pages: 775-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790766
[Journal Article] Validation of the triaxial accelerometer for the evaluation of physical activity in Japanese patients with COPD.2012
- Author(s)
  Kanda M, Minakata Y, Matsunaga K, Sugiura H, Hirano T, Koarai A, Akamatsu K, Ichikawa T, Ichinose M.
- Journal Title
  
  Intern Med
  
  Volume: 51 Pages: 369-75
- NAID
  130002062007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790766
[Journal Article] Cigarette smoke augments the expression and responses of toll-like receptor 3 in human macrophages.2012
- Author(s)
  Koarai A, Yanagisawa S, Sugiura H, Ichikawa T, Akamatsu K, Hirano T, Nakanishi M, Matsunaga K, Minakata Y, Ichinose M.
- Journal Title
  
  Respirology
  
  Volume: 17 Pages: 1018-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790766
[Journal Article] Increase of 27-hydroxycholesterol in the airways of patients with COPD: possible role of 27-hydroxycholesterol in tissue fibrosis.2012
- Author(s)
  Kikuchi T, Sugiura H, Koarai A, Ichikawa T, Minakata Y, Matsunaga K, Nakanishi M, Hirano T, Akamatsu K, Yanagisawa S, Furukawa K, Kawabata H, Ichinose M.
- Journal Title
  
  Chest
  
  Volume: 142 Pages: 329-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790766
[Journal Article] Inhibitory effects of theophylline on the peroxynitrite-augmented release of matrix metalloproteinases by lung fibroblasts.2012
- Author(s)
  Sugiura H, Kawabata H, Ichikawa T, Koarai A, Yanagisawa S, Kikuchi T, Minakata Y, Matsunaga K, Nakanishi M, Hirano T, Akamatsu K, Furukawa K, Ichinose M.
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol
  
  Volume: 302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790766
[Journal Article] 25-Hydroxycholesterol enhances cytokine release and Toll-like receptor 3 response in airway epithelial cells.2012
- Author(s)
  Koarai A, Yanagisawa S, Sugiura H, Ichikawa T, Kikuchi T, Furukawa K, Akamatsu K, Hirano T, Nakanishi M, Matsunaga K, Minakata Y, Ichinose M.
- Journal Title
  
  Respir Res.
  
  Volume: 13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790766
[Journal Article] Increased 25-hydroxycholesterol concentrations in the lungs of patients with chronic obstructive pulmonary disease.2012
- Author(s)
  Sugiura H, Koarai A, Ichikawa T, Minakata Y, Matsunaga K, Hirano T, Akamatsu K, Yanagisawa S, Furusawa M, Uno Y, Yamasaki M, Satomi Y, Ichinose M.
- Journal Title
  
  Respirology
  
  Volume: 17 Pages: 533-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790766
[Journal Article] Increase of nitrosative stress in patients with eosinophilic pneumonia.2011
- Author(s)
  Furukawa K, Sugiura H, Matsunaga K, Ichikawa T, Koarai A, Hirano T, Yanagisawa S, Minakata Y, Akamatsu K, Kanda M, Nishigai M, Ichinose M.
- Journal Title
  
  Respir Res
  
  Volume: 17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790766
[Journal Article] High COPD prevalence in patients with liver disease.2010
- Author(s)
  Minakata Y, Ueda H, Akamatsu K, Kanda M, Yanagisawa S, Ichikawa T, Koarai A, Hirano T, Sugiura H, Matsunaga K, Ichinose M.
- Journal Title
  
  Intern Med.
  
  Volume: 49 Pages: 2687-91
- NAID
  130000413428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790766
[Presentation] The role of 27-hydroxycholesterol in the pathogenesis of bronchial asthma2021
- Author(s)
  Tatsunori Ito, Tomohiro Ichikawa
- Organizer
  APSR
- Data Source
  KAKENHI-PROJECT-21K08147
[Presentation] 管支喘息の病態における27－hydroxycholesterolの役割2021
- Author(s)
  伊藤辰徳, 市川朋宏, 橋本裕一郎, 滝田克也, 一ノ瀬正和, 杉浦久敏
- Organizer
  日本呼吸器学会
- Data Source
  KAKENHI-PROJECT-21K08147
[Presentation] The decrease of mitochondrial biogenesis contributes to airway epithelial barrier dysfunction in asthma2019
- Author(s)
  Tomohiro Ichikawa, Tsutomu Saito et al.
- Organizer
  第68回日本アレルギー学会 (English session)
- Data Source
  KAKENHI-PROJECT-18K08166
[Presentation] The Decrease of Mitochondrial Biogenesis Contributes to Airway Epithelial Barrier Dysfunction in Asthma2019
- Author(s)
  Tsutomu Saito, Tomohiro Ichikawa, et al
- Organizer
  ATS international conference 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08166
[Presentation] 気管支喘息における気道上皮細胞の機能障害とミトコンドリア新生の役割に関する検討2019
- Author(s)
  齋藤勉, 市川朋宏　ほか７名
- Organizer
  第59回日本呼吸器学会
- Data Source
  KAKENHI-PROJECT-18K08166
[Presentation] Toll-Like Receptor-3 Activation Augments Matrix Metalloproteinases Production Through Reactive Nitrogen Species Generation In Human Lung Fibroblasts,2014
- Author(s)
  Ichikawa T, Sugiura H, Koarai A, Minakata Y, Kikuchi T, Kanai K, Yamamoto N, Ichinose M.
- Organizer
  ATS International Conference 2014
- Place of Presentation
  San Diego, USA
- Year and Date
  2014-05-21
- Data Source
  KAKENHI-PROJECT-26860612
[Presentation] COPD肺における25-hydroxycholesterolの産生と生物学的作用についての検討2013
- Author(s)
  市川朋宏
- Organizer
  第9回呼吸器バイオマーカー研究会
- Place of Presentation
  東京
- Year and Date
  2013-03-02
- Data Source
  KAKENHI-PROJECT-22790766
[Presentation] Toll 様受容体 3の活性化は誘導型 NO合成酵素の発現を介して肺線維芽細胞からの matrix metalloproteinase の産生を亢進する.2013
- Author(s)
  市川朋宏
- Organizer
  第53回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Year and Date
  2013-04-21
- Data Source
  KAKENHI-PROJECT-22790766
[Presentation] 25-hydroxycholesterolは肺線維芽細胞に作用して気道リモデリングを促進する2011
- Author(s)
  市川朋宏
- Organizer
  第51回日本呼吸器学会
- Place of Presentation
  (東日本大震災のため誌面のみ)
- Data Source
  KAKENHI-PROJECT-22790766
[Presentation] 25-hydroxycholesterolは肺線維芽細胞に作用して気道リモデリングを促進する.2011
- Author(s)
  市川朋宏
- Organizer
  第51回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22790766
[Presentation] Peroxynitrite augments fibroblast-mediated tissue remodeling through NF-κB activation2010
- Author(s)
  Tomohiro Ichikawa
- Organizer
  The 6^<th> International Conference on the Biology, Chemistry, and Therapeutic Application of Nitric Oxide
- Place of Presentation
  Kyoto International Conference Center, Kyoto
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-22790766

Ichikawa Tomohiro 市川 朋宏

市川 朋宏 イチカワ トモヒロ

ICHIKAWA Tomohiro 市川 朋宏

Research Projects

Research Products

Identification of new biomarker for non-type 2 severe asthmaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

CYP27A1: A novel target for treatment of asthmaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of mitochondrial dysfunction in epithelial barrier disruptionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肺構成細胞の細胞老化の機序の解明～慢性閉塞性肺疾患の病態制御を目指して～Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of MMPs in refractory asthmaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 臨床免疫・アレルギー科2015

Author(s)

Total Pages

Publisher

Data Source

[Book] COPD 大規模臨床研究の全容2012

Author(s)

Publisher

Data Source

[Book] 日本胸部臨床2011

Author(s)

Total Pages

Publisher

Data Source

[Book] 日本胸部臨床2011

Author(s)

Publisher

Data Source

[Book] アレルギー・免疫2010

Author(s)

Publisher

Data Source

[Book] アレルギー・免疫17巻12号2010

Author(s)

Publisher

Data Source

[Journal Article] CYP27A1-27-hydroxycholesterol axis in the respiratory system contributes to house dust mite-induced allergic airway inflammation2024

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] PGC-1α regulates airway epithelial barrier dysfunction induced by house dust mite2021

Author(s)

Journal Title

Data Source

[Journal Article] 25-hydroxycholesterol promotes fibroblast-mediated tissue remodeling through NF-κB dependent pathway.2013

Author(s)

Journal Title

Data Source

[Journal Article] 25-Hydroxycholesterol promotes fibroblast-mediated tissue remodeling through NF-κB dependent pathway2013

Author(s)

Journal Title

DOI

Ichikawa Tomohiro 市川朋宏

市川朋宏イチカワトモヒロ

ICHIKAWA Tomohiro 市川朋宏