yokota kazuhiro 横田和浩

… Alternative Names

横田和浩ヨコタカズヒロ

Yokota Kazuhiro 横田和浩

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Researcher Number	20406440
Other IDs
Affiliation (Current)	2025: 埼玉医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 埼玉医科大学, 医学部, 准教授 2021: 埼玉医科大学, 医学部, 講師 2015 – 2017: 埼玉医科大学, 医学部, 講師 2014: 埼玉医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related / Orthopaedic surgery / Metabolomics
Keywords	Principal Investigator 関節リウマチ / 炎症性サイトカイン / 破骨細胞 / 破骨細胞分化誘導因 / シングルセル解析 / RANKL / 骨破壊 / ヤヌスキナーゼ阻害薬 / 細胞内シグナル伝達経路 / 破骨細胞分化誘導因子（RANKL） … More / 関節破壊 / 免疫学 / 骨代謝異常 / 抗CCP抗体 / 抗環状シトルリン化ペプチド抗体 / 破骨細胞様細胞 / 骨粗鬆症 / 全身性骨代謝異常 / 自己免疫性疾患 / 動脈硬化症 / Wntシグナル / 骨芽細胞 / 石灰化 / 動脈硬化 / 心血管疾患 / 腫瘍壊死因子 / 末梢血単核球 / 骨芽細胞系細胞 Less

Single-cell analysis and identification of inflammatory osteoclasts responsible for the pathophysiology of rheumatoid arthritisPrincipal Investigator
- Principal Investigator
  
  横田和浩
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Saitama Medical University
Analysis of molecular mechanism of systemic bone metabolism abnormality in systemic autoimmune diseasesPrincipal Investigator
- Principal Investigator
  
  Yokota Kazuhiro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Saitama Medical University
Functional Analysis of Osteoblast-Like Cells Originate from Peripheral Blood.Principal Investigator
- Principal Investigator
  
  Yokota Kazuhiro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Saitama Medical University

All 2024 2023 2022 2021 2018 2017 2016

All Journal Article Presentation Book

[Book] Pharma Medica2021
- Author(s)
  横田　和浩
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-21K08464
[Journal Article] Osteoclast differentiation in rheumatoid arthritis2024
- Author(s)
  Kazuhiro Yokota
- Journal Title
  
  Immunological Medicine
  
  Volume: 47 Issue: 1 Pages: 6-11
- DOI
  10.1080/25785826.2023.2220931
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08464
[Journal Article] Characterization and Function of Tumor Necrosis Factor alpha and Interleukin‐6‐Induced Osteoclasts in Rheumatoid Arthritis2021
- Author(s)
  Yokota Kazuhiro、Sato Kojiro、Miyazaki Takashi、Aizaki Yoshimi、Tanaka Shinya、Sekikawa Miyoko、Kozu Noritsune、Kadono Yuho、Oda Hiromi、Mimura Toshihide
- Journal Title
  
  Arthritis & Rheumatology
  
  Volume: in press Issue: 7 Pages: 1145-1154
- DOI
  10.1002/art.41666
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09118, KAKENHI-PROJECT-21K07326, KAKENHI-PROJECT-21K08464
[Journal Article] Detection of synovial inflammation in rheumatic diseases using superb microvascular imaging: Comparison with conventional power Doppler imaging2018
- Author(s)
  Yokota K, Wada T, Akiyama Y, Mimura T
- Journal Title
  
  Mod Rheumatol
  
  Volume: 28 Issue: 2 Pages: 327-333
- DOI
  10.1080/14397595.2017.1337288
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09902, KAKENHI-PROJECT-16K21329
[Journal Article] Inflammation and osteoclasts2017
- Author(s)
  Yokota Kazuhiro
- Journal Title
  
  Japanese Journal of Clinical Immunology
  
  Volume: 40 Issue: 5 Pages: 367-376
- DOI
  10.2177/jsci.40.367
- NAID
  130006251855
- ISSN
  0911-4300, 1349-7413
- Language
  Japanese
- Open Access
- Data Source
  KAKENHI-PROJECT-16K21329
[Journal Article] A case of new-onset rheumatoid vasculitis becoming evident in the course of treatment for <i>Pneumocystis jirovecii</i> pneumonia2017
- Author(s)
  Ikuma D, Yokota K, Sato K, Mimura T.
- Journal Title
  
  Japanese Journal of Clinical Immunology
  
  Volume: 40 Issue: 1 Pages: 78-82
- DOI
  10.2177/jsci.40.78
- NAID
  130005665661
- ISSN
  0911-4300, 1349-7413
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10488, KAKENHI-PROJECT-16K21329
[Journal Article] A Case of Abdominal Aortic Retroperitoneal and Mesenteric Amyloid Light Chain Amyloidoma2016
- Author(s)
  Kazuhiro Yokota, Dai Kishida, Hidekazu Kayano, Masahide Yazaki, Yuki Shimada, Yuji Akiyama, and Toshihide Mimura
- Journal Title
  
  Case Reports in Rheumatology
  
  Volume: 2016 Pages: 1-5
- DOI
  10.1155/2016/4146030
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K21329
[Presentation] Janus Kinase Inhibitor Suppresses the Differentiation and Function of Tumor Necrosis Factor-alpha and Interleukin-6- Induced Osteoclasts in Peripheral Blood Monocytes from Patients with Rheumatoid Arthritis2023
- Author(s)
  Kazuhiro Yokota, Yoshimi Aizaki, Hiroshi Kajiyama, Yasuto Araki, Hiroaki Yazawa, Yuji Akiyama, Toshihide Mimura
- Organizer
  European League Against Rheumatism 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08464
[Presentation] Function of Tumor Necrosis Factor alpha and Interleukin-6- Induced Osteoclasts Derived from Peripheral Blood Monocytes in Patients with Rheumatoid Arthritis2023
- Author(s)
  Kazuhiro Yokota, Yoshimi Aizaki, Hiroshi Kajiyama, Yasuto Araki, Yuji Akiyama, Toshihide Mimura
- Organizer
  第67回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-21K08464
[Presentation] RANKL誘導性破骨細胞とTNF-αとIL-6誘導性破骨細胞に対するJAK阻害薬の作用2023
- Author(s)
  横田　和浩、相崎　良美、和田　琢、矢澤　宏晃、梶山　浩、荒木　靖人、秋山　雄次、三村　俊英
- Organizer
  第51回日本臨床免疫学会総会
- Data Source
  KAKENHI-PROJECT-21K08464
[Presentation] Effects of Janus Kinase Inhibitor on TNF-α and IL-6-Induced Osteoclasts and RANKL-Induced Osteoclasts in Peripheral Blood Monocytes from Patients with Rheumatoid Arthritis.2023
- Author(s)
  Kazuhiro Yokota, Yoshimi Aizaki, Takuma Tsuzuki Wada, Hiroshi Kajiyama, Yasuto Araki, Hiroaki Yazawa, Yuji Akiyama, Toshihide Mimura
- Organizer
  American College of Rheumatology Convergence 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08464
[Presentation] Characteristics of Tumor Necrosis Factor-alpha and Interleukin-6-Induced Osteoclasts in Peripheral Blood and Bone Tissue from Patients with Rheumatoid Arthritis2022
- Author(s)
  Kazuhiro Yokota, Miyoko Sekikawa, Shinya Tanaka, Yoshimi Aizaki, Yuho Kadono, Hiromi Oda, and Toshihide Mimura
- Organizer
  European League Against Rheumatism 2022
- Data Source
  KAKENHI-PROJECT-21K08464
[Presentation] 関節リウマチ患者の末梢血と骨組織におけるTNF-αとIL-6誘導性破骨細胞の特徴2022
- Author(s)
  横田　和浩、関川　三四子、田中　伸哉、相崎　良美、門野　夕峰、織田　弘美、秋山　雄次、三村　俊英
- Organizer
  第50回日本臨床免疫学会総会
- Data Source
  KAKENHI-PROJECT-21K08464
[Presentation] Interleukin-6 Induces Osteoblastic Differentiation in Human Peripheral Blood Mononuclear Cells.2022
- Author(s)
  Kazuhiro Yokota, Yoshimi Aizaki, Shinya Tanaka, Hiroshi Kajiyama, Yasuto Araki, Yuho Kadono, Hiromi Oda, Toshihide Mimura
- Organizer
  第66回日本リウマチ学会総会・学術集
- Data Source
  KAKENHI-PROJECT-21K08464
[Presentation] 関節リウマチの臨床免疫学的なアプローチと治療2021
- Author(s)
  横田和浩
- Organizer
  第49回日本臨床免疫学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-21K08464
[Presentation] 関節リウマチにおける骨破壊のメカニズムJAK阻害剤によるその制御2021
- Author(s)
  横田和浩
- Organizer
  第23回日本骨粗鬆症学会／第39回日本骨代謝学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K08464
[Presentation] Functional Differences Between RANKL-Induced Osteoclasts and Tumor Necrosis Factor alpha and Interleukin-6- Induced Osteoclasts Differentiated From Peripheral Blood Mononuclear Cells in Patients With Rheumatoid Arthritis2021
- Author(s)
  Kazuhiro Yokota, Kojiro Sato, Yoshimi Aizaki, Shinya Tanaka, Noritsune Kozu, Yuho Kadono, Hiromi Oda, Toshihide Mimura
- Organizer
  第65回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-21K08464
[Presentation] Characterization and Function of Tumor Necrosis Factor α and Interleukin-6 Induced Osteoclasts in Rheumatoid Arthritis2021
- Author(s)
  Kazuhiro Yokota, Kojiro Sato, Yoshimi Aizaki, Shinya Tanaka, Miyoko Sekikawa, Noritsune Kozu, Yuho Kadono, Hiromi Oda and Toshihide Mimura
- Organizer
  American College of Rheumatology/Association of Rheumatology Health Professionals Annual Meeting, 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08464
[Presentation] 関節リウマチ患者骨組織における破骨細胞様細胞（osteoclast-like cells；OLCs）の同定2018
- Author(s)
  横田　和浩、田中　伸哉、関川　三四子、相崎　良美、佐藤　浩二郎、織田　弘美、三村俊英
- Organizer
  第4回日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-16K21329
[Presentation] Presence of RANK- Osteoclast-like Cells in the Bone of Patients with Rheumatoid Arthritis2018
- Author(s)
  Kazuhiro Yokota, Shinya Tanaka, Kojiro Sato, Yoshimi Aizaki, Hiromi Oda, Toshihide Mimura
- Organizer
  第62回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K21329
[Presentation] ＩＬ-6刺激によるヒト末梢血単核球から骨芽細胞様細胞への分化誘導機構の解析2017
- Author(s)
  横田和浩，相崎良美，三村俊英
- Organizer
  第3回日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-16K21329
[Presentation] The Efficacy and Safety of Adding Low-Dose Prednisolone (PSL) Induction Therapy of Tocilizumab (TCZ) in Patients with Rhematoid Arthritis (RA)．2017
- Author(s)
  Kazuhiro Yokota, Takanori Azuma, Hayato Nagasawa, Junji Hayashi, Kenji Takagi, Yuji Akiyama, Yoshihiro Yoshida, Hiroshi Kajiyama, Yu Funakubo Asanuma, Toshihide Mimura
- Organizer
  第6１回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-16K21329
[Presentation] IL-6刺激によるヒト末梢血単核球の骨芽細胞様細胞への分化誘導と機能解析2016
- Author(s)
  横田和浩，相崎良美，秋山雄次，三村俊英
- Organizer
  第44回日本臨床免疫学会総会
- Place of Presentation
  京王プラザホテル（新宿）
- Data Source
  KAKENHI-PROJECT-16K21329
[Presentation] TNFαはヒト末梢血単核球から骨芽細胞様細胞を誘導する2016
- Author(s)
  横田　和浩、相崎　良美、三村　俊英
- Organizer
  第2回日本骨免疫学会
- Place of Presentation
  ホテルモントーレ沖縄スパ＆リゾート（沖縄県恩納村）
- Year and Date
  2016-07-06
- Data Source
  KAKENHI-PROJECT-26870546
[Presentation] 関節リウマチにおける新規炎症性骨吸収細胞の発現・機能・分化誘導機構の解析2016
- Author(s)
  横田和浩
- Organizer
  第3回日本リウマチ学会ベーシックリサーチカンファレンス
- Place of Presentation
  アキバプラザ（秋葉原）
- Invited
- Data Source
  KAKENHI-PROJECT-16K21329
[Presentation] TNFα Induces the Calcified Nodule Formations and Increased Osteoblastic Marker Expression in Human Peripheral Blood Mononuclear Cells on Dentin Slices2016
- Author(s)
  Kazuhiro Yokota, Yuji Akiyama, Kojiro Sato, Yoshimi Aizaki, Yasuto Araki, Hiroshi Kajiyama, Yu Funakubo Asanuma, and Toshihide Mimura
- Organizer
  第60回日本リウマチ学会総会・学術集会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-16K21329
[Presentation] TNFα Induces the Calcified Nodule Formations and Increased Osteoblastic Marker Expression in Human Peripheral Blood Mononuclear Cells on Dentin Slices.2016
- Author(s)
  Kazuhiro Yokota, Yuji Akiyama, Kojiro Sato, Yoshimi Aizaki, Yasuto Araki, Hiroshi Kajiyama, Yu Funakubo Asanuma, Toshihide Mimura
- Organizer
  第60回日本リウマチ学会総会・学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-04-23
- Data Source
  KAKENHI-PROJECT-26870546
[Presentation] IL-1β Promotes Differentiation of Human Osteoclast-like Cells Induced by a Combination of TNFα and IL-6 from CD14+ Monocytes2016
- Author(s)
  Kazuhiro Yokota, Kojiro Sato, Yoshimi Aizaki, Yasuto Araki, Hiroshi Kajiyama, Yu Funakubo Asanuma, Yuji Akiyama, and Toshihide Mimura
- Organizer
  第60回日本リウマチ学会総会・学術集会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-16K21329

1. MIMUA Toshihide

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. AIZAKI Yoshimi

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. 佐藤浩二郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

yokota kazuhiro 横田 和浩

横田 和浩 ヨコタ カズヒロ

Yokota Kazuhiro 横田 和浩

Research Projects

Research Products

Co-Researchers

Single-cell analysis and identification of inflammatory osteoclasts responsible for the pathophysiology of rheumatoid arthritisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of molecular mechanism of systemic bone metabolism abnormality in systemic autoimmune diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional Analysis of Osteoblast-Like Cells Originate from Peripheral Blood.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Pharma Medica2021

Author(s)

Publisher

Data Source

[Journal Article] Osteoclast differentiation in rheumatoid arthritis2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characterization and Function of Tumor Necrosis Factor alpha and Interleukin‐6‐Induced Osteoclasts in Rheumatoid Arthritis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Detection of synovial inflammation in rheumatic diseases using superb microvascular imaging: Comparison with conventional power Doppler imaging2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inflammation and osteoclasts2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] A case of new-onset rheumatoid vasculitis becoming evident in the course of treatment for <i>Pneumocystis jirovecii</i> pneumonia2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] A Case of Abdominal Aortic Retroperitoneal and Mesenteric Amyloid Light Chain Amyloidoma2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] Janus Kinase Inhibitor Suppresses the Differentiation and Function of Tumor Necrosis Factor-alpha and Interleukin-6- Induced Osteoclasts in Peripheral Blood Monocytes from Patients with Rheumatoid Arthritis2023

Author(s)

Organizer

Data Source

[Presentation] Function of Tumor Necrosis Factor alpha and Interleukin-6- Induced Osteoclasts Derived from Peripheral Blood Monocytes in Patients with Rheumatoid Arthritis2023

Author(s)

Organizer

Data Source

[Presentation] RANKL誘導性破骨細胞とTNF-αとIL-6誘導性破骨細胞に対するJAK阻害薬の作用2023

Author(s)

Organizer

Data Source

[Presentation] Effects of Janus Kinase Inhibitor on TNF-α and IL-6-Induced Osteoclasts and RANKL-Induced Osteoclasts in Peripheral Blood Monocytes from Patients with Rheumatoid Arthritis.2023

Author(s)

Organizer

Data Source

yokota kazuhiro 横田和浩

横田和浩ヨコタカズヒロ

Yokota Kazuhiro 横田和浩