KIMOTO Michiko 木本路子

Researcher Number	20415144
Other IDs
Affiliation (based on the past Project Information) *help	2013: 独立行政法人理化学研究所, ライフサイエンス技術基盤研究センター, 上級研究員 2012: 独立行政法人理化学研究所, 核酸合成生物学研究チーム, 研究員 2008 – 2010: The Institute of Physical and Chemical Research, 核酸合成生物学研究チーム, 研究員 2007: 独立行政法人理化学研究所, タンパク質基盤研究グループ, 研究員 2007: The Institute of Physical and Chemical Research, タンパク質基盤研究グループ, 研究員 2006: 独立行政法人理化学研究所, タンパク質制御高分子研究チーム, 研究員
Review Section/Research Field	Principal Investigator Living organism molecular science Except Principal Investigator Living organism molecular science
Keywords	Principal Investigator 転写 / 人工塩基対 / T7 RNAポリメラーゼ / ｔRNA / 無細胞タンパク質合成系 / T7 RNA ポリメラーゼ / mRNA / tRNA / 複製 / 翻訳 … More / 培養 / 培養細胞 / RNA干渉 / バイオテクノロジー / 核酸 / 生体分子 / 栄光基 / ビオチン / ライブラリー / セレクション / PCR / 蛍光基 / DNA / RNA … More Except Principal Investigator 進化工学 / アプタマー / 核酸 / バイオテクノロジー / 生体分子 / SELEX / in vitroセレクション / PCR / 核酸アプタマー / 人工塩基対 Less

Development of a translation system using expanded genetic alphabets through unnatural base pairsPrincipal Investigator
- Principal Investigator
  
  KIMOTO Michiko
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Institute of Physical and Chemical Research
Activities of functional RNA molecules containing unnatural bases in cultured cellsPrincipal Investigator
- Principal Investigator
  
  KIMOTO Michiko
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  The Institute of Physical and Chemical Research
Creation of highly-functional nucleic acids by unnatural base pair systems
- Principal Investigator
  
  HIRAO Ichiro
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Living organism molecular science
- Research Institution
  The Institute of Physical and Chemical Research
転写における人工塩基対の選択性と効率に影響を及ぼす鋳型DNA塩基配列の網羅的解析Principal Investigator
- Principal Investigator
  
  木本路子
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  The Institute of Physical and Chemical Research

All 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book Patent

[Book] Creation of Unnatural Base Pair Systems Toward New DNA/RNA Biotechnologies, Chemical Biology of Nucleic Acids–Fundamentals and Clinical Applications- RNA Technologies2014
- Author(s)
  Michiko Kimoto, Ichiro, Hirao
- Publisher
  Springer-Verlag
- Data Source
  KAKENHI-PROJECT-24710256
[Book] Methods in Molecular Biology(Site-Specific Incorporation of Extra Components into RNA by Transcription Using Unnatural Base Pair Systems.)2010
- Author(s)
  M. Kimoto, I. Hirao
- Publisher
  The Humana Press Inc.(in press)
- Data Source
  KAKENHI-PROJECT-20710176
[Book] The Chemical Biology of Nucleic Acids2010
- Author(s)
  I. Hirao, M. Kimoto
- Data Source
  KAKENHI-PROJECT-19201046
[Book] The Chemical Biology of Nucleic Acids(Expansion of the Genetic Alphabet in Nucleic Acids by Creating New Base Pairs.)2010
- Author(s)
  I. Hirao, M. Kimoto
- Publisher
  John Wiley & Sons(in press)
- Data Source
  KAKENHI-PROJECT-20710176
[Journal Article] Site-specific functional labeling of nucleic acids by in vitro replication and transcription using unnatural base pair systems2013
- Author(s)
  M. Kimoto, Y. Hikida, I. Hirao
- Journal Title
  
  Israel. J. Chem
  
  Volume: 53 Pages: 450-468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24710256
[Journal Article] Site-specific functional labeling of nucleic acids by in vitro replication and transcription using unnatural base pair systems.2013
- Author(s)
  M. Kimoto, Y. Hikida, and I. Hirao
- Journal Title
  
  Israel J. Chem.
  
  Volume: 53 Issue: 6-7 Pages: 450-468
- DOI
  10.1002/ijch.201300013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24710256
[Journal Article] Generation of high-affinity DNA aptamers using an expanded genetic alphabet.2013
- Author(s)
  M. Kimoto, R. Yamashige, K. Matsunaga, S. Yokoyama, I. Hirao
- Journal Title
  
  Nat. Biotechnol.
  
  Volume: 31 Issue: 5 Pages: 453-457
- DOI
  10.1038/nbt.2556
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24710256
[Journal Article] Site-specific Functionalization of RNA Molecules by an Unnatural Base Pair Transcription System via Click Chemistry2012
- Author(s)
  Takumi Ishizuka, Michiko Kimoto, Akira Sato, Ichiro Hirao
- Journal Title
  
  Chem. Coummn.
  
  Volume: Vol. 48 Issue: 88 Pages: 10835-10837
- DOI
  10.1039/c2cc36293g
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J07372, KAKENHI-PROJECT-24710256
[Journal Article] Natural versus artificial creation of base pairs in DNA : origin of nucleobases from the perspectives of unnatural base pair studies2012
- Author(s)
  Hirao I, Kimoto M, Yamashige R
- Journal Title
  
  Acc. Chem. Res
  
  Volume: 45 Issue: 12 Pages: 2055-65
- DOI
  10.1021/ar200257x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24710256
[Journal Article] Unnatural base pair systems toward the expansion of the genetic alphabet in the central dogma2012
- Author(s)
  Hirao I, Kimoto M
- Journal Title
  
  Proceedings of the Japan Academy, Series B
  
  Volume: 88 Issue: 7 Pages: 345-367
- DOI
  10.2183/pjab.88.345
- NAID
  130001924754
- ISSN
  0386-2208, 1349-2896
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24710256
[Journal Article] PCR amplification and transcription for site-specific labeling of large RNA molecules by a two-unnatural-base-pair system2012
- Author(s)
  Kimoto M, Yamashige R, Yokoyama S, Hirao
- Journal Title
  
  J. Nucleic Acids
  
  Volume: 2012 Pages: 230943-230943
- DOI
  10.1155/2012/230943
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24710256
[Journal Article] Unnatural base pair systems for sensing and diagnostic applications2011
- Author(s)
  M. Kimoto, R. S. Cox 3rd, I. Hirao
- Journal Title
  
  Expert Rev. Mol. Diagn.
  
  Volume: 11 Pages: 321-331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] Monitoring the site-specific incorporation of dual fluorophore-quencher base analogues for target DNA detection by an unnatural base pair system. Org2011
- Author(s)
  R. Yamashige, M. Kimoto, T. Mitsui, S. Yokoyama, I. Hirao
- Journal Title
  
  Biomol. Chem.
  
  Volume: 412 Pages: 325-339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] A unique fluorescent base analogue for the expansion of the genetic alphabet.2010
- Author(s)
  Michiko Kimoto
- Journal Title
  
  J.Am.Chem.Soc.
  
  Volume: 132 Pages: 4988-4989
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] A unique fluorescent base analogue for the expansion of the genetic alphabet2010
- Author(s)
  M. Kimoto, T. Mitsui, S. Yokoyama, I. Hirao
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 132 Pages: 4988-4989
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] Site-specific incorporation of extra components into RNA by transcription using unnatural base pair systems2010
- Author(s)
  M. Kimoto, I. Hirao
- Journal Title
  
  Methods, Mol. Biol.
  
  Volume: 634 Pages: 355-369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] A unique fluorescent base analogue for the expansion of the genetic alphabet.2010
- Author(s)
  M. Kimoto, T. Mitsui, S. Yokoyama, I. Hirao
- Journal Title
  
  J. Am. Chem. Soc. 132
  
  Pages: 4988-4989
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20710176
[Journal Article] Site-specific fluorescent probing of RNA molecules by unnatural base-pair transcription for local structural conformation analysis.2010
- Author(s)
  Y. Hikida, M. Kimoto, S. Yokoyama, I. Hirao
- Journal Title
  
  Nature Protocols (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20710176
[Journal Article] Site-specific fluorescent probing of RNA molecules by unnatural base-pair transcription for local structural conformation analysis2010
- Author(s)
  Y. Hikida, M. Kimoto, S. Yokoyama, I. Hirao
- Journal Title
  
  Nature Protocols
  
  Volume: 5 Pages: 1312-1323
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] A unique fluorescent base analogue for the expansion of the genetic alphabet2010
- Author(s)
  M. Kimoto, T. Mitsui, S. Yokoyama, I. Hirao
- Journal Title
  
  J.Am.Chem.Soc. 132
  
  Pages: 4988-4989
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] A new unnatural base pair system between fluorophore and quencher base analogues for nucleic acid-based imaging technology2010
- Author(s)
  M. Kimoto, T. Mitsui, R. Yamashige, A. Sato, S. Yokoyama, I. Hirao
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 132 Pages: 15418-15426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] A new unnatural base pair system between fluorophore and quencher base analogues for nucleic acid-based imaging technology.2010
- Author(s)
  Michiko Kimoto
- Journal Title
  
  J Am.Chem.Soc.
  
  Volume: 132 Pages: 15418-15426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] An unnatural base pair system for efficient PCR amplification and functionalization of DNA molecules2009
- Author(s)
  M. Kimoto, R. Kawai, T. Mitsui, S. Yokoyama, I. Hirao
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] Site-specific incorporation of functional components into RNA by transcription using unnatural base pair systems2009
- Author(s)
  Michiko Kimoto
- Journal Title
  
  Nucleic Acids Symp.Ser. 53
  
  Pages: 73-74
- Data Source
  KAKENHI-PROJECT-20710176
[Journal Article] Site-specific incorporation of functional components into RNA by transcription using unnatural base pair systems.2009
- Author(s)
  M. Kimoto, A. Sato, R. Kawai, S. Yokoyama, I. Hirao
- Journal Title
  
  Nucleic Acids Symp. Ser. 53
  
  Pages: 73-74
- Data Source
  KAKENHI-PROJECT-20710176
[Journal Article] An unnatural base pair system for efficient PCR amplification and functionalization of DNA molecules.2009
- Author(s)
  M. Kimoto, R. Kawai, T. Mitsui, S. Yokoyama, I. Hirao
- Journal Title
  
  Nucleic Acids Res. 37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20710176
[Journal Article] An unnatural base pair system for efficient PCR amplification and functionalization of DNA molecules.2009
- Author(s)
  M.Kimoto
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] An unnatural base pair system for efficient PCR amplification and functionalization of DNA molecules2009
- Author(s)
  M. Kimoto, R. Kawai, T. Mitsui, S. Yokoyama, I. Hirao
- Journal Title
  
  Nucleic Acids Res. 37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] An unnatural base pair system for efficient PCR amplification and functionalization of DNA molecules.2009
- Author(s)
  木本路子
- Journal Title
  
  Nucleic Acids Research 37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20710176
[Journal Article] Site-specific incorporation of functional components into RNA by transcription using unnatural base pair systems2009
- Author(s)
  Michiko Kimoto
- Journal Title
  
  Nucleic Acids Symp.Ser. 53
  
  Pages: 73-74
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] Sequences around the unnatural base pair in DNA templates for efficient replication.2008
- Author(s)
  M. Kimoto
- Journal Title
  
  Nucleic Acids Symp. Ser. 52
  
  Pages: 457-458
- Data Source
  KAKENHI-PROJECT-20710176
[Journal Article] Efficient PCR amplification by an unnatural base pair system.2008
- Author(s)
  M. Kimoto, R. Kawai, T. Mitsui, S. Yokoyama, I. Hirao
- Journal Title
  
  Nucleic Acids Symp. Ser. 52
  
  Pages: 469-470
- Data Source
  KAKENHI-PROJECT-20710176
[Journal Article] Sequences around the unnatural base pair in DNA templates for efficient replication.2008
- Author(s)
  M. Kimoto, R. Kawai, T. Mitsui, S. Yokoyama, I. Hirao
- Journal Title
  
  Nucleic Acids Symp. Ser. 52
  
  Pages: 457-458
- Data Source
  KAKENHI-PROJECT-20710176
[Journal Article] Efficient PCR amplification by an unnatural base pair system.2008
- Author(s)
  M.Kimoto
- Journal Title
  
  Nucleic Acids Symp.Ser.
  
  Volume: 52 Pages: 469-470
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] Efficient PCR amplification by an unnatural base pair system.2008
- Author(s)
  M. Kimoto
- Journal Title
  
  Nucleic Acids Symp. Ser. 52
  
  Pages: 469-470
- Data Source
  KAKENHI-PROJECT-20710176
[Journal Article] Sequences around the unnatural base pair in DNA templates for efficient replication.2008
- Author(s)
  M.Kimoto
- Journal Title
  
  Nucleic Acids Symp.Ser.
  
  Volume: 52 Pages: 457-458
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] Fluorescent probing for RNA molecules by an unnatural base-pair system.2007
- Author(s)
  M.Kimoto
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 35 Pages: 5360-5369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] Cytostatic evaluations of nucleoside analogs related to unnatural base pairs for a genetic expansion system.2007
- Author(s)
  M.Kimoto
- Journal Title
  
  Bioorg.Med.Chem.Lett.
  
  Volume: 17 Pages: 5582-5585
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] Fluorescent probing for RNA molecules by an unnatural base-pair system2007
- Author(s)
  木本路子
- Journal Title
  
  Nucleic Acids Research 35
  
  Pages: 5360-5369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18710197
[Journal Article] Fluorescent probing for RNA molecules by an unnatural base-pair system2007
- Author(s)
  M. Kimoto, T. Mitsui, Y. Harada, A. Sato, S. Yokoyama, I. Hirao
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 35 Pages: 5360-5369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] An efficient unnatural base pair for PCR amplification2007
- Author(s)
  I. Hirao, T. Mitsui, M. Kimoto, S. Yokoyama
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 129 Pages: 15549-15555
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] Cytostatic evaluations of nucleoside analogs related to unnatural base pairs for a genetic expansion system2007
- Author(s)
  木本路子
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 17
  
  Pages: 5582-5585
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18710197
[Journal Article] Unnatural base pair systems for sensing and diagnostic applications.
- Author(s)
  Michiko Kimoto
- Journal Title
  
  Expert Rev.Mol.Diagn.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] Natural vs artificial creation of base pairs in DNA : origin of nucleobases from the perspectives of unnatural base pair studies
- Author(s)
  I. Hirao, M. Kimoto, R. Yamashige
- Journal Title
  
  Acc. Chem. Res.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] Highly specific unnatural base pair systems as a third base pair for PCR amplification
- Author(s)
  R. Yamashige, M. Kimoto, Y. Takezawa, A. Sato, T. Mitsui, S. Yokoyama, I. Hirao
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Journal Article] Site-specific fluorescent probing of RNA molecules by unnatural base-pair transcription for local structural conformation analysis
- Author(s)
  Y. Hikida, M. Kimoto, S. Yokoyama, I. Hirao
- Journal Title
  
  Nature Protocols (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19201046
[Patent] 高選択性・高効率でPCR増幅が可能なDNA2008
- Inventor(s)
  平尾一郎, 木本路子, 横山茂之
- Industrial Property Rights Holder
  理化学研究所、タグシクスバイオ株式会社
- Industrial Property Number
  2008-094255
- Filing Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-20710176
[Presentation] Site-specific functional labeling of RNA molecules by using unnatural base pair systems2014
- Author(s)
  Michiko Kimoto
- Organizer
  The 65th Fujihara Seminar International Symposium on Synthetic Biology of Unnatural Base Pairs and Amino Acids
- Place of Presentation
  北海道・苫小牧
- Data Source
  KAKENHI-PROJECT-24710256
[Presentation] Thermal stability of hydrophobic unnatural base pairs in DNA duplexes2014
- Author(s)
  Michiko Kimoto, Ichiro Hirao
- Organizer
  XVIth SCNAC
- Place of Presentation
  チェコ、チェスキークルムノフ
- Data Source
  KAKENHI-PROJECT-24710256
[Presentation] Thermal stability of hydrophobic unnatural base pairs in duplexes2014
- Author(s)
  Michiko Kimoto, Ichiro, Hirao
- Organizer
  XVIth SCNAC
- Place of Presentation
  チェコ・チェスキークルムノフ
- Data Source
  KAKENHI-PROJECT-24710256
[Presentation] 複製可能な人工塩基対を組み込んだDNAを創る2013
- Author(s)
  木本路子
- Organizer
  「細胞を創る」研究会6
- Place of Presentation
  慶応技術大学鶴岡タウンキャンパス
- Data Source
  KAKENHI-PROJECT-24710256
[Presentation] Variation of Genetic Alphabets of Nucleobases2013
- Author(s)
  Michiko Kimoto, Ichiro Hirao
- Organizer
  International Astrobiology Workshop 2013
- Place of Presentation
  相模原、JAXA
- Invited
- Data Source
  KAKENHI-PROJECT-24710256
[Presentation] Expanding the Genetic Alphabet for Generating High-affinity DNA Aptmaer2013
- Author(s)
  Michiko Kimoto, Ken-ichiro Matsunaga, Rie Yamashige, Ichiro hirao
- Organizer
  OTS Annual Meeting 2013
- Place of Presentation
  イタリア・ナポリ
- Data Source
  KAKENHI-PROJECT-24710256
[Presentation] High-affinity DNA aptamer selection by a genetic alphabet expansion PCR system2013
- Author(s)
  Michiko Kimoto, Ken-ichiro Matsunaga, Rie Yamashige, Ichiro Hirao
- Organizer
  第51回日本生物物理学会年会シンポジウム生命現象の理解と核酸医薬を指向した機能性核酸の研究の最前線
- Place of Presentation
  国立京都国際会館
- Invited
- Data Source
  KAKENHI-PROJECT-24710256
[Presentation] Site-specific labeling of RNA by a replication-transcription system using a genetic alphabet expansion with two unnatural base pairs2013
- Author(s)
  Michiko Kimoto, Rie Yamashige, Ichiro Hirao
- Organizer
  3rd International Conference on Nucleic Acid-Protein Chemistry and Structural Biology
- Place of Presentation
  米国・アトランタ
- Data Source
  KAKENHI-PROJECT-24710256
[Presentation] Variation of Genetic Alphabets of Nucleobases2013
- Author(s)
  Michiko Kimoto, Ichiro Hirao
- Organizer
  International Astrobiology workshop 2013
- Place of Presentation
  相模原・JAXA
- Data Source
  KAKENHI-PROJECT-24710256
[Presentation] High-affinity DNA aptamer selection by a genetic alphabet expansion PCR system2013
- Author(s)
  Michiko Kimoto, Ken-ichiro Matsunaga, Rie Yamashige, Ichiro Hirao
- Organizer
  第51回日本生物物理学会年会シンポジウム
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-24710256
[Presentation] Site-specific labeling of RNA by a replication-transcription system using a genetic alphabet expansion with two unnatural base pairs」2013
- Author(s)
  Michiko Kimoto, Rie Yamashige, Ichiro Hirao
- Organizer
  3rd International Conference on Nucleic Acid-Protein Chemistry Structural Biology
- Place of Presentation
  米国、アトランタ
- Data Source
  KAKENHI-PROJECT-24710256
[Presentation] 複製可能な人工塩基対を組み込んだDNAを創る2013
- Author(s)
  木本　路子
- Organizer
  「細胞を創る」研究会 6.0
- Place of Presentation
  慶応義塾大学鶴岡タウンキャンパス
- Data Source
  KAKENHI-PROJECT-24710256
[Presentation] Site-specific functional labeling of RNA molecules by using unnatural base pair systems2013
- Author(s)
  Michiko Kimoto
- Organizer
  The 65th Fujihara Seminar International Symposium on Synthetic Biology of Unnatural Base Pairs and Amino Acids
- Place of Presentation
  北海道、苫小牧
- Data Source
  KAKENHI-PROJECT-24710256
[Presentation] Expanding the Genetic Alphabet for Generating High-affinity DNA Aptamer2013
- Author(s)
  Michiko Kimoto, Ken-ichiro Matsunaga, Rie Yamashige, Ichiro Hirao
- Organizer
  OTS Annual Meeting 2013
- Place of Presentation
  イタリア、ナポリ
- Data Source
  KAKENHI-PROJECT-24710256
[Presentation] The third base pair ‘Ds-Px’ in PCR amplification2012
- Author(s)
  Rie Yamashige, Michiko Kimoto, Yusuke Takezawa, Akira Sato, Tsuneo Mitsui, Shigeyuki Yokoyama, Ichiro Hirao
- Organizer
  XX IRT - 20th International Roundtable on Nucleosides, Nucleotides and Nucleic Acids
- Place of Presentation
  カナダ　モントリオール
- Data Source
  KAKENHI-PROJECT-24710256
[Presentation] Site-specific labeling of RNA molecules by an unnatural base pair transcription system coupled with click chemistry2012
- Author(s)
  Takumi Ishizuka, Michiko Kimoto,Akira Sato,Shigeyuki Yokoyama, Ichiro Hirao
- Organizer
  Fluorescent Biomolecules and their Building Blocks - Design and Applications
- Place of Presentation
  スウェーデンヨーテボリ
- Data Source
  KAKENHI-PROJECT-24710256
[Presentation] Creation of DNA aptamers using libraries with five different bases by an unnatural base pair system2012
- Author(s)
  Michiko Kimoto, Rie Yamashige, Ken-ichiro Matsunaga, Shigeyuki Yokoyama, Ichiro Hirao
- Organizer
  第39回国際核酸化学シンポジウム
- Place of Presentation
  名古屋大学豊田講堂
- Data Source
  KAKENHI-PROJECT-24710256
[Presentation] Site-specific fluorescent probing of RNA molecules by an unnatural base pair system and its applications2012
- Author(s)
  Michiko Kimoto, Yasushi Hikida, Shuang Liu, Shigeyuki Yokoyama, Ichiro Hirao
- Organizer
  Fluorescent Biomolecules and their Building Blocks - Design and Applications
- Place of Presentation
  スウェーデンヨーテボリ
- Data Source
  KAKENHI-PROJECT-24710256
[Presentation] Site-specific fluorescent probing of RNA molecules by an unnatural base pair system and its applications2012
- Author(s)
  Michiko Kimoto, Yasushi Hikida, Shuang Liu, Shigeyuki Yokoyama, Ichiro Hirao
- Organizer
  Fluorescent Biomolecules and their Building Blocks - Design and Applications
- Place of Presentation
  スウェーデンヨーテボリ
- Data Source
  KAKENHI-PROJECT-24710256
[Presentation] 人工塩基対システムおよびクリック反応による機能性RNAの部位特異的修飾2012
- Author(s)
  石塚匠, 木本路子, 佐藤旭, 横山茂之, 平尾一郎
- Organizer
  第14回日本RNA学会年会
- Place of Presentation
  東北大学百周年記念会館
- Data Source
  KAKENHI-PROJECT-24710256
[Presentation] The third base pair'Ds-Px'in PCR amplification2012
- Author(s)
  Rie Yamashige, Michiko Kimoto, Yusuke Takezawa, Akira Sato, Tsuneo Mitsui, Shigeyuki Yokoyama, Ichiro Hirao
- Organizer
  XX IRT-20th International Roundtable on Nucleosides, Nucleotides and Nucleic Acids
- Place of Presentation
  カナダ、モントリオール
- Data Source
  KAKENHI-PROJECT-24710256
[Presentation] Site-specific labeling of RNA molecules by an unnatural base pair transcription system coupled with click chemistry2012
- Author(s)
  Takumi Ishizuka, Michiko Kimoto, Akira Sato, Shigeyuki Yokoyama, Ichiro Hirao
- Organizer
  Fluorescent Biomolecules and their Building Blocks - Design and Applications
- Place of Presentation
  スウェーデンヨーテボリ
- Data Source
  KAKENHI-PROJECT-24710256
[Presentation] Site-specific Incorporation of a Unique Fluorescent Base Analogue into DNA and RNA using an Unnatural Base Pair System.2010
- Author(s)
  Michiko Kimoto
- Organizer
  IRT2010 : International Roundtable on NNN
- Place of Presentation
  フランス・リヨン
- Year and Date
  2010-09-01
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] 高効率でPCR可能な人工塩基対システムの最適化2010
- Author(s)
  木本路子
- Organizer
  BMB2010 第33回日本分子生物学会年会・第63回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] Site-specific incorporation of a fluorescent nucleobase analogue into nucleic acids using an unnatural base pair system.2010
- Author(s)
  Michiko Kimoto
- Organizer
  Pachifichem 2010
- Place of Presentation
  米国・ハワイ
- Year and Date
  2010-12-19
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] Development of unnatural fluorophore-quencher base pair systems for the expansion of the genetic alophabet.2010
- Author(s)
  Michiko Kimoto
- Organizer
  第37回国際核酸化学シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2010-11-12
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] PCR amplification and transcription by a hydrophobic unnatural base pair system for site-specific RNA labeling2010
- Author(s)
  M. Kimoto
- Organizer
  EVOLVING DNA POLYMERASES: CHEMISTRY MEETS BIOLOGY
- Place of Presentation
  スイスモンテベリタ
- Year and Date
  2010-05-10
- Data Source
  KAKENHI-PROJECT-20710176
[Presentation] PCR amplification and transcription by a hydrophobic unnatural base pair system for site-specific RNA labeling.2010
- Author(s)
  Michiko Kimoto
- Organizer
  EVOLVING DNA POLYMERASES : CHEMISTRY MEETS BIOLOGY
- Place of Presentation
  スイス・モンテヴェリタ
- Year and Date
  2010-05-12
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] 人工塩基対システムによる機能性核酸の蛍光標識化2010
- Author(s)
  木本路子
- Organizer
  第12回日本RNA学会年会
- Place of Presentation
  東京
- Year and Date
  2010-07-29
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] Site-specific incorporation of functional components into RNA by transcription using unnatural base pair systems2009
- Author(s)
  木本路子
- Organizer
  第6回国際核酸化学シンポジウム
- Place of Presentation
  岐阜県高山市
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-20710176
[Presentation] PCRと転写で機能する人工塩基対による機能性コンポーネントのRNA中への位置選択的取り込み2009
- Author(s)
  木本路子
- Organizer
  第11回RNAミーティング
- Place of Presentation
  新潟
- Year and Date
  2009-07-29
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] PCRと転写で機能する人工塩基対による機能性コンポーネントのRNA中への位置選択的取り込み2009
- Author(s)
  木本路子
- Organizer
  第11回RNAミーティング
- Place of Presentation
  新潟
- Year and Date
  2009-07-29
- Data Source
  KAKENHI-PROJECT-20710176
[Presentation] Site-specific incorporation of functional components into RNA by transcription using unnatural base pair systems2009
- Author(s)
  M. Kimoto
- Place of Presentation
  岐阜県高山市
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-20710176
[Presentation] PCRと転写で機能する人工塩基対による機能性コンポーネントのRNA中への位置選択的取り込み2009
- Author(s)
  木本路子
- Organizer
  第11回rnaミーティング
- Place of Presentation
  新潟
- Year and Date
  2009-07-29
- Data Source
  KAKENHI-PROJECT-20710176
[Presentation] Efficient PCR amplification functionalization by an unnatural base pair system2009
- Author(s)
  M. Kimoto
- Organizer
  ACS 237th National Meeting
- Place of Presentation
  米国ユタ
- Year and Date
  2009-03-23
- Data Source
  KAKENHI-PROJECT-20710176
[Presentation] Site-specific incorporation of functional components into RNA by transcription using unnatural base pair systems2009
- Author(s)
  木本路子
- Organizer
  第6回国際核酸化学シンポジウム
- Place of Presentation
  岐阜県高山市
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] PCRと転写で機能する人工塩基対による機能性コンポーネントのRNA中への一選択的取り込み2009
- Author(s)
  木本路子
- Organizer
  第11回RNAミーティング
- Place of Presentation
  新潟
- Year and Date
  2009-07-29
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] Site-specific incorporation of functional components into RNA by transcription using unnatural base pair systems2009
- Author(s)
  M. Kimoto
- Organizer
  第6回国際核酸化学シンポジウム
- Place of Presentation
  岐阜
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] Site-specific fluorescent labeling of RNA fragments by transcription using an unnatural base pair system2008
- Author(s)
  M. Kimoto
- Organizer
  ACS 236th National Meeting
- Place of Presentation
  Philadelphia
- Year and Date
  2008-08-20
- Data Source
  KAKENHI-PROJECT-20710176
[Presentation] Site-specific incorporation of fluorescent 2-amino-6-(2-thienyl)purine into RNA by transcription using an unnatural base pair2008
- Author(s)
  M.Kimoto
- Organizer
  XIVth symposium on chemistry of nucleic acid components
- Place of Presentation
  Czech Republic
- Year and Date
  2008-06-10
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] 高効率でPCR増幅可能な人工塩基対システムの構築2008
- Author(s)
  木本路子
- Organizer
  分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] Site-specific incorporation of fluorescent 2-amino-6-(2-thienyl)purine into RNA by transcription using an unnatural base pair system2008
- Author(s)
  M. Kimoto
- Organizer
  XIVth symposium on chemistry of nucleic acid components
- Place of Presentation
  チェコチェスキークルムロフ
- Year and Date
  2008-06-10
- Data Source
  KAKENHI-PROJECT-20710176
[Presentation] Site-specific fluorescent labeling of RNA fragments by transcription using an unnatural base pair system2008
- Author(s)
  M.Kimoto
- Organizer
  ACS 236th National Meeting
- Place of Presentation
  Philadelphia
- Year and Date
  2008-08-20
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] 高効率でPCR増幅可能な人工塩基対システムの構築2008
- Author(s)
  木本路子
- Organizer
  分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20710176
[Presentation] Site-specific incorporation of fluorescent 2-amino-6-(2-thienyl)purine in to RNA by transcription using an unnatural base pair2008
- Author(s)
  M. Kimoto
- Organizer
  XIVth symposium on chemistry of nucleic acid components
- Place of Presentation
  Czech Republic
- Year and Date
  2008-06-10
- Data Source
  KAKENHI-PROJECT-20710176
[Presentation] Sequences around the unnatural base pair in DNA templates for efficient replication2008
- Author(s)
  M. Kimoto
- Organizer
  Joint Symposium of 18th International Roundtable on Nucleosides, Nucleotides and Nucleic Acids (IRTXVIII) and 35th International Symposium on Nucleic Acids Chemistry (SNAC)
- Place of Presentation
  京都
- Year and Date
  2008-09-09
- Data Source
  KAKENHI-PROJECT-20710176
[Presentation] Site-specific fluorescent labeling of RNA fragments by transcription using an unnatural base pair system2008
- Author(s)
  M. Kimoto
- Organizer
  ACS 236th National Meeting
- Place of Presentation
  米国フィラデルフィア
- Year and Date
  2008-08-20
- Data Source
  KAKENHI-PROJECT-20710176
[Presentation] 複製と転写における疎水性人工塩基対の選択性2007
- Author(s)
  木本路子
- Organizer
  第2回無細胞生命科学研究会
- Place of Presentation
  東京
- Year and Date
  2007-10-19
- Data Source
  KAKENHI-PROJECT-19201046
[Presentation] 人工塩基対システムにおける蛍光性6-ヘタリルプリン誘導体の応用2007
- Author(s)
  木本路子
- Organizer
  分子系の構造と電子状態-「生物物質科学」を目指して
- Place of Presentation
  理化学研究所和光キャンパス
- Year and Date
  2007-04-06
- Data Source
  KAKENHI-PROJECT-18710197
[Presentation] 複製と転写における疎水性人工塩基対の選択性2007
- Author(s)
  木本路子
- Organizer
  第2回無細胞生命科学研究会
- Place of Presentation
  東京大学・柏キャンパスメディアホール
- Year and Date
  2007-10-19
- Data Source
  KAKENHI-PROJECT-18710197

1. MITSUI Tsuneo (60345155)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
2. HIRAO Ichiro (50173216)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
3. KAWAI Rie (10415135)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

KIMOTO Michiko 木本 路子

Research Projects

Research Products

Co-Researchers

Development of a translation system using expanded genetic alphabets through unnatural base pairsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Activities of functional RNA molecules containing unnatural bases in cultured cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Creation of highly-functional nucleic acids by unnatural base pair systems

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

転写における人工塩基対の選択性と効率に影響を及ぼす鋳型DNA塩基配列の網羅的解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Creation of Unnatural Base Pair Systems Toward New DNA/RNA Biotechnologies, Chemical Biology of Nucleic Acids–Fundamentals and Clinical Applications- RNA Technologies2014

Author(s)

Publisher

Data Source

[Book] Methods in Molecular Biology(Site-Specific Incorporation of Extra Components into RNA by Transcription Using Unnatural Base Pair Systems.)2010

Author(s)

Publisher

Data Source

[Book] The Chemical Biology of Nucleic Acids2010

Author(s)

Data Source

[Book] The Chemical Biology of Nucleic Acids(Expansion of the Genetic Alphabet in Nucleic Acids by Creating New Base Pairs.)2010

Author(s)

Publisher

Data Source

[Journal Article] Site-specific functional labeling of nucleic acids by in vitro replication and transcription using unnatural base pair systems2013

Author(s)

Journal Title

Data Source

[Journal Article] Site-specific functional labeling of nucleic acids by in vitro replication and transcription using unnatural base pair systems.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Generation of high-affinity DNA aptamers using an expanded genetic alphabet.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Site-specific Functionalization of RNA Molecules by an Unnatural Base Pair Transcription System via Click Chemistry2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Natural versus artificial creation of base pairs in DNA : origin of nucleobases from the perspectives of unnatural base pair studies2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Unnatural base pair systems toward the expansion of the genetic alphabet in the central dogma2012

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] PCR amplification and transcription for site-specific labeling of large RNA molecules by a two-unnatural-base-pair system2012

Author(s)

Journal Title

DOI

Data Source

KIMOTO Michiko 木本路子