Nakatake Yuki 中武悠樹

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NAKATAKE Yuhki 中武悠樹

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Researcher Number	20415251
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立成育医療研究センター, 細胞医療研究部, 室長
Affiliation (based on the past Project Information) *help	2018 – 2020: 慶應義塾大学, 医学部(信濃町), 講師 2017: 慶應義塾大学, 医学部(信濃町), 助教 2012 – 2015: 慶應義塾大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Biological Sciences / Basic Section 42040:Laboratory animal science-related / Developmental biology Except Principal Investigator Developmental biology / Gastroenterology
Keywords	Principal Investigator 合成生物学 / CAGプロモーター / 恒常的プロモーター / 発現ベクター / 恒常的プロモータ / 転写制御 / 恒常発現 / 網羅的解析 / 遺伝子発現 / プロモーター … More / 小腸上皮細胞 / 分化誘導 / 再生医療 / ヒトES細胞 / NEUROG3 / CDX2 / 転写因子 / 腸管発生 / 幹細胞 … More Except Principal Investigator ZSCAN4 / 組織幹細胞 / Zscan4 / マウス胚性幹細胞 / ノックアウト / マウス発生学 / 遺伝子機能解析 / テロメア伸長 / ゲノム安定化 / 若返り / BMI1 / LGR5 / 膵炎 / 幹/前駆細胞 / 膵臓 / 幹細胞マーカー / 膵組織幹細胞 / 膵組織再生 Less

母性因子の人工誘導による全能性の再獲得Principal Investigator
- Principal Investigator
  
  中武悠樹
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
Identification of novel and powerful constitutive promoter than CAGPrincipal Investigator
- Principal Investigator
  
  NAKATAKE Yuhki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Keio University
Novel molecular mechanisms for enabling the maintenance and rejuvenation of tissue stem cells
- Principal Investigator
  
  KO Minoru
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Developmental biology
- Research Institution
  Keio University
Induction of intestinal epithelial cells from CDX2 inducible human ES cellsPrincipal Investigator
- Principal Investigator
  
  Nakatake Yuhki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Developmental biology
- Research Institution
  Keio University
Identification of endocrine and exocrine stem/protenitor cells in the pancreas.
- Principal Investigator
  
  KO Shigeru
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University

All 2020 2018 2016 2015 2014

All Journal Article Presentation Book

[Book] 実験医学増刊　Vol.33 No.2　239-2462015
- Author(s)
  山水康平、中武悠樹、洪繁、洪実
- Total Pages
  8
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-26840083
[Journal Article] Generation and Profiling of 2,135 Human ESC Lines for the Systematic Analyses of Cell States Perturbed by Inducing Single Transcription Factors2020
- Author(s)
  Nakatake Y、Ko S B.H.、Sharov A A.、Wakabayashi S、Murakami M、Sakota M、Chikazawa N、Ookura C、Sato S、Ito N、Ishikawa-Hirayama M、Mak Siu S、Jakt Lars M、Ueno T、Hiratsuka K、Matsushita M、Goparaju S K、Akiyama T、Ishiguro K、Oda M、Gouda N、Umezawa A、Akutsu H、Nishimura K、Matoba R、Ohara O、Ko M S.H.
- Journal Title
  
  Cell Reports
  
  Volume: 31 Issue: 7 Pages: 107655-107655
- DOI
  10.1016/j.celrep.2020.107655
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08085, KAKENHI-PROJECT-18K06039, KAKENHI-PROJECT-19K06492, KAKENHI-PUBLICLY-20H04929, KAKENHI-PUBLICLY-20H05395
[Journal Article] Gene array analysis of neural crest cells identifies transcription factors necessary for direct conversion of embryonic fibroblasts into neural crest cells.2016
- Author(s)
  Tsutomu Motohashi, Natsuki Watanabe, Masahiro Nishioka, Yuhki Nakatake, Piao Yulan, Hiromi Mochizuki, Yoshifumi Kawamura, Minoru S. H. Ko, Naoki Goshima and Takahiro Kunisada
- Journal Title
  
  Biology Open
  
  Volume: 5 Issue: 3 Pages: 311-322
- DOI
  10.1242/bio.015735
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460273, KAKENHI-PROJECT-25670092, KAKENHI-PROJECT-26840083
[Journal Article] Unprecedented cell-selection using ultra-quick freezing combined with aquaporin expression.2014
- Author(s)
  Kato, Y., T. Miyauchi, Y. Abe, D. Koji´c, M. Tanaka, N. Chikazawa, Y. Nakatake, S. B. H. Ko, D. Kobayashi, A. Hazama, S. Fujiwara, T. Uchida, M. Yasui
- Journal Title
  
  PLoS ONE
  
  Volume: 9 Issue: 2 Pages: e87644-e87644
- DOI
  10.1371/journal.pone.0087644
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24570114, KAKENHI-PROJECT-24591023, KAKENHI-PROJECT-24792152
[Presentation] CAGプロモータを超える新規恒常的プロモーターの同定2018
- Author(s)
  中武悠樹
- Organizer
  第41回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06039
[Presentation] ヒト多能性幹細胞の分化運命を決定する転写因子の網羅的同定と細胞分化制御技術の開発2016
- Author(s)
  中武悠樹、洪実
- Organizer
  第15回日本再生医療学会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-26840083
[Presentation] Large-scaled transgene activation on human embryonic stem cells2016
- Author(s)
  Yuhki Nakatake et.al.
- Organizer
  第14回幹細胞シンポジウム
- Place of Presentation
  淡路夢舞台国際会議場（兵庫県淡路市）
- Year and Date
  2016-05-20
- Invited
- Data Source
  KAKENHI-PROJECT-26840083
[Presentation] Large-scaled transgene activation on human embryonic stem cells2015
- Author(s)
  Yuhki Nakatake et.al.
- Organizer
  ICSB2015
- Place of Presentation
  シンガポール（シンガポール）
- Year and Date
  2015-11-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26840083
[Presentation] comprehensive transcriptional factor screening for trophectodermal lineage in human ES cell2015
- Author(s)
  Yuhki Nakatake、Mayumi Oda、Yann Tapponnier、Minoru Ko
- Organizer
  CHIR-JST meeting
- Place of Presentation
  カナダ（トロント）
- Year and Date
  2015-10-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26840083
[Presentation] Large-scaled transgene activation on human embryonic stem cell2015
- Author(s)
  Yuhki Nakatake et.al.
- Organizer
  JST CREST-PRESTO joint international symposium～Structural Biological Dynamics: From Molecules to Life with 60 trillion Cells～
- Place of Presentation
  東京大学伊藤ホール（東京都文京区）
- Year and Date
  2015-11-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26840083
[Presentation] Effect of CDX2 overexpression in human ES cell2014
- Author(s)
  Yuhki Nakatake、Mayumi Oda、Minoru Ko
- Organizer
  CHIR-JST meeting
- Place of Presentation
  オタワ（カナダ）
- Year and Date
  2014-10-26
- Data Source
  KAKENHI-PROJECT-26840083

1. KO Shigeru (90402578)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. KO Minoru (50631199)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. ISHIGURO Hiroshi (90303651)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. YAMAMOTO Akiko (60402385)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NIIDA Shunpei (10137630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MATSUURA Toshihiro (80501626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 秋山智彦 (20570691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 小田真由美 (80567511)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. WATANABE Natsuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. FUJIWARA Shoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 本橋力

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakatake Yuki 中武 悠樹

NAKATAKE Yuhki 中武 悠樹

Research Projects

Research Products

Co-Researchers

母性因子の人工誘導による全能性の再獲得Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of novel and powerful constitutive promoter than CAGPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel molecular mechanisms for enabling the maintenance and rejuvenation of tissue stem cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Induction of intestinal epithelial cells from CDX2 inducible human ES cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of endocrine and exocrine stem/protenitor cells in the pancreas.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 実験医学増刊 Vol.33 No.2 239-2462015

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Generation and Profiling of 2,135 Human ESC Lines for the Systematic Analyses of Cell States Perturbed by Inducing Single Transcription Factors2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gene array analysis of neural crest cells identifies transcription factors necessary for direct conversion of embryonic fibroblasts into neural crest cells.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Unprecedented cell-selection using ultra-quick freezing combined with aquaporin expression.2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] CAGプロモータを超える新規恒常的プロモーターの同定2018

Author(s)

Organizer

Data Source

[Presentation] ヒト多能性幹細胞の分化運命を決定する転写因子の網羅的同定と細胞分化制御技術の開発2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Large-scaled transgene activation on human embryonic stem cells2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Large-scaled transgene activation on human embryonic stem cells2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] comprehensive transcriptional factor screening for trophectodermal lineage in human ES cell2015

Author(s)

Organizer

Nakatake Yuki 中武悠樹

NAKATAKE Yuhki 中武悠樹

[Book] 実験医学増刊　Vol.33 No.2　239-2462015