Nagai Yuji 永井裕司

… Alternative Names

Researcher Number	20415409
Other IDs
Affiliation (Current)	2020: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所脳機能イメージング研究部, 研究員(任常)
Affiliation (based on the past Project Information) *help	2019: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所脳機能イメージング研究部, 研究員(任常) 2016 – 2017: 量子科学技術研究開発機構, 放射線医学総合研究所・脳機能イメージング研究部, 研究員 2010 – 2012: National Institute of Radiological Sciences, 分子イメージング研究センター, 研究員 2011: 独立行政法人放射線医学総合研究所, 研究員 2009: National Institute of Radiological Sciences, 分子イメージング研究センター, 技術員
Review Section/Research Field	Principal Investigator Radiation science / Basic Section 52040:Radiological sciences-related Except Principal Investigator Basic / Social brain science / Neuroscience in general
Keywords	Principal Investigator 核医学(PETを含む) / パーキンソン病 / ポジトロンCT / 高次脳機能障害 / トランスレーショナルリサーチ / トランスルーショナルリサーチ / 遂行機能障害 / ドーパミン受容体 / 化学遺伝学 / PET … More Except Principal Investigator … More

インビボイメージングによる非ヒト霊長類脳へのDREADD技術の最適化に関する研究Principal InvestigatorOngoing
- Principal Investigator
  
  永井裕司
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes for Quantum and Radiological Science and Technology
In vivo neural projection mapping technology with a novel PET ligand
- Principal Investigator
  
  Minamimoto Takafumi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Basic / Social brain science
- Research Institution
  National Institutes for Quantum and Radiological Science and Technology
Neural mechanism of cost-benefit based controlling motivation
- Principal Investigator
  
  Minamimoto Takafumi
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Basic / Social brain science
- Research Institution
  National Institutes for Quantum and Radiological Science and Technology
In vivo molecular neuroimaging for executive dysfunction in non-human primate model of Parkinson's diseasePrincipal Investigator
- Principal Investigator
  
  NAGAI Yuji
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  National Institute of Radiological Sciences
Distribution of dopamine receptors in the marmoset brain : a PET study
- Principal Investigator
  
  TSUJIMOTO Satoshi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  Kobe University
In vivo molecular neuroimaging for motor or cognitive dysfunction in non-human primate model of Parkinson's diseasePrincipal Investigator
- Principal Investigator
  
  NAGAI Yuji
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  National Institute of Radiological Sciences

All 2020 2019 2017 2016 2015 2012 Other

All Journal Article Presentation

[Journal Article] Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys2020
- Author(s)
  Nagai Y, Miyakawa N, et al.
- Journal Title
  
  Nat Neurosci
  
  Volume: -
- DOI
  10.1101/854513
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08138, KAKENHI-PROJECT-19H05467, KAKENHI-ORGANIZER-15H05871, KAKENHI-PUBLICLY-19H04996, KAKENHI-INTERNATIONAL-15K21731
[Journal Article] PET imaging-guided chemogenetic silencing reveals a critical role of primate rostromedial caudate in reward evaluation2016
- Author(s)
  Nagai Y, Kikuchi E, Lerchner W, Inoue Ki, Ji B, Eldridge MA, Kaneko H, Kimura Y, Oh-Nishi A, Hori Y, Kato Y, Hirabayashi T, Fujimoto A, Kumata K, Zhang MR, Aoki I, SuharaT, Higuchi M, Takada M, Richmond BJ, Minamimoto T.
- Journal Title
  
  Nat Commun
  
  Volume: 7 Pages: 13605-13605
- DOI
  10.1038/ncomms13605
- NAID
  120005898960
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01419, KAKENHI-PUBLICLY-15H01431, KAKENHI-PUBLICLY-15H01434, KAKENHI-PLANNED-15H05917, KAKENHI-PUBLICLY-16H01611, KAKENHI-PROJECT-16H02454, KAKENHI-PROJECT-15H06872, KAKENHI-PROJECT-26282221, KAKENHI-PROJECT-15K12772, KAKENHI-PROJECT-15K14316, KAKENHI-PROJECT-16KT0193
[Journal Article] Correlation between decreased motor activity and dopaminergic degeneration in the ventrolateral putamen in monkeys receiving repeated MPTP administrations: A positron emission tomography study2012
- Author(s)
  Yuji Nagai, Takafumi Minamimoto, Kiyoshi Ando, Shigeru Obayashi, Hiroshi Ito, Nobuhiko Ito, Tetsuya Suhara
- Journal Title
  
  Neuroscience research
  
  Volume: 73巻 Pages: 61-67
- DOI
  10.1016/j.neures.2012.02.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791469
[Presentation] A novel ligand selectively visualizes and activates chemogenetic receptors in non-human primates2020
- Author(s)
  Yuji Nagai
- Organizer
  The 93rd Annual Meeting of the Japanese Pharmacological Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08138
[Presentation] 化学遺伝学とPETイメージングによるサル脳活動操作とモニタリング2020
- Author(s)
  永井裕司, 宮川尚久, Xi-Ping Haung, Samuel T. Slocum, Yan Xiong, 堀由紀子, 小山佳, 季斌, 平林敏行, 藤本淳, 三村喬生, Justin G. English, Jing Liu, 井上謙一, 熊田勝志, 関千江, 張明栄, 須原哲也, 高田昌彦, 樋口真人, Jian Jin, Bryan L. Roth, 南本敬史
- Organizer
  第66回日本獣医画像診断学会
- Data Source
  KAKENHI-PROJECT-19K08138
[Presentation] A novel ligand “deschloroclozapine” selectively visualizes and activates chemogenetic receptors in non-human primates2019
- Author(s)
  Nagai Y, Miyakawa N, et al.
- Organizer
  BrainPET 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08138
[Presentation] 3.Encoding expected reward value for formulating goal-directed decision in the rostro-medial caudate and the ventral pallidum.2017
- Author(s)
  Fujimoto A, Hori Y, Nagai Y, McCairn KW, Hirabayashi T, Kikuchi E, Takada M, Suhara T, Minamimoto T
- Organizer
  Society for Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26282221
[Presentation] 8.Predicted reward value in the rostromedial caudate and the ventral pallidum for goal-directed action in monkeys.2017
- Author(s)
  Fujimoto A, Hori Y, Nagai Y, McCairn KW, Hirabayashi T, Kikuchi E, Takada M, Suhara T, Minamimoto T
- Organizer
  第４０回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-26282221
[Presentation] 1.Region-specific effects of bilateral inactivation of limbic striatum on reward-related behavior in monkeys.2015
- Author(s)
  Kikuchi E, Hori Y, Nagai Y, Suhara T, Samejima K, Minamimoto T.
- Organizer
  日本神経科学学会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-08-28
- Data Source
  KAKENHI-PROJECT-26282221
[Presentation] In vivo PET imaging of the behaviorally active designer receptor in macaque monkeys.
- Author(s)
  4)Nagai Y, Kikuchi E, Lerchner W, Inoue K, Oh-Nishi A, Kaneko H, Kato Y, Hori Y, Ji B, Kumata K, Zhang MR, Aoki I, Suhara T, Takada M, Higuchi M, Richmond BJ, Minamimoto T.
- Organizer
  Society for Neuroscience
- Place of Presentation
  Washington DC
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-26282221
[Presentation] In vivo PET imaging of the behaviorally active designer receptor in macaques
- Author(s)
  1)Nagai Y, Kikuchi E, Lerchner W, Inoue K, Oh-Nishi A, Kaneko H, Kato Y, Hori Y, Ji B, Kumata K, Zhang MR, Aoki I, Suhara T, Takada M, Higuchi M, Richmond BJ, Minamimoto T.
- Organizer
  Neuro2014
- Place of Presentation
  横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-26282221

1. Minamimoto Takafumi (50506813)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. KIKUCHI Erika

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
3. TSUJIMOTO Satoshi (20539241)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MINAMIMOTO Takafumi (23011006)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
5. JI Bin (80392223)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. HORI Yukiko (30433246)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
7. HIRABAYASHI Toshiyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. INOUE Ken-ichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 高田昌彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 藤本淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 井上智

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 三村喬生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nagai Yuji 永井 裕司

永井 裕司 ナガイ ユウジ

NAGAI Yuji 永井 裕司

Research Projects

Research Products

Co-Researchers

インビボイメージングによる非ヒト霊長類脳へのDREADD技術の最適化に関する研究Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

In vivo neural projection mapping technology with a novel PET ligand

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Neural mechanism of cost-benefit based controlling motivation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

In vivo molecular neuroimaging for executive dysfunction in non-human primate model of Parkinson's diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Distribution of dopamine receptors in the marmoset brain : a PET study

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

In vivo molecular neuroimaging for motor or cognitive dysfunction in non-human primate model of Parkinson's diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PET imaging-guided chemogenetic silencing reveals a critical role of primate rostromedial caudate in reward evaluation2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Correlation between decreased motor activity and dopaminergic degeneration in the ventrolateral putamen in monkeys receiving repeated MPTP administrations: A positron emission tomography study2012

Author(s)

Journal Title

DOI

Data Source

[Presentation] A novel ligand selectively visualizes and activates chemogenetic receptors in non-human primates2020

Author(s)

Organizer

Data Source

[Presentation] 化学遺伝学とPETイメージングによるサル脳活動操作とモニタリング2020

Author(s)

Organizer

Data Source

[Presentation] A novel ligand “deschloroclozapine” selectively visualizes and activates chemogenetic receptors in non-human primates2019

Author(s)

Organizer

Data Source

[Presentation] 3.Encoding expected reward value for formulating goal-directed decision in the rostro-medial caudate and the ventral pallidum.2017

Author(s)

Organizer

Data Source

[Presentation] 8.Predicted reward value in the rostromedial caudate and the ventral pallidum for goal-directed action in monkeys.2017

Author(s)

Organizer

Data Source

[Presentation] 1.Region-specific effects of bilateral inactivation of limbic striatum on reward-related behavior in monkeys.2015

Author(s)

Nagai Yuji 永井裕司

永井裕司ナガイユウジ

NAGAI Yuji 永井裕司