Hashimoto Daigo 橋本大吾

… Alternative Names

橋本大吾ハシモトダイゴ

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Researcher Number	20419576
Other IDs
Affiliation (Current)	2025: 北海道大学, 医学研究院, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 北海道大学, 医学研究院, 准教授 2017 – 2019: 北海道大学, 医学研究院, 准教授 2015 – 2016: 北海道大学, 大学病院, 講師 2014: 北海道大学, 大学病院, 助教 2007: Kyushu University, 大学病院, 医員 2006: 九州大学, 病院, 医員
Review Section/Research Field	Principal Investigator Hematology / Basic Section 54010:Hematology and medical oncology-related
Keywords	Principal Investigator 移植片対宿主病 / GVHD / マクロファージ / 同種造血幹細胞移植 / 同種造血細胞移植 / 組織幹細胞 / 造血幹細胞移植 / 移植片対白血病効果 / 炎症記憶 / T細胞疲弊 … More / 胆管上皮 / TGF-beta / 胆管上皮幹細胞 / オルガノイド / 肝臓オルガノイド / 慢性GVHD / リポソーム / 線維芽細胞 / ドライアイ症候群 / HSP47 / 筋線維芽細胞 / ドライアイ / 線維化 / 慢性移植片対宿主病 / 腸内細菌叢 / 腸管 / JAK阻害剤 / 皮膚 / JAK1/2阻害剤 / ステロイド / 貪食細胞 / galactosylceramide / NKT細胞 / 白血病 Less

Development of a novel transplantation method targeting the epigenetics of T cells, leukemia Cells, and epithelial cellsPrincipal Investigator
- Principal Investigator
  
  橋本大吾
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Hokkaido University
Liver organoid-based study of macrophage-induced injury of liver stem cells in GVHDPrincipal Investigator
- Principal Investigator
  
  Hashimoto Daigo
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Hokkaido University
Development of a novel therapy for chronic GVHD targeting a macrophage-myofibroblast axis in fibrotic processPrincipal Investigator
- Principal Investigator
  
  Hashimoto Daigo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Hokkaido University
Reconstitution of mononuclear phagocyte system following allogeneic hematopoietic stem cell transplantationPrincipal Investigator
- Principal Investigator
  
  Hashimoto Daigo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Hokkaido University
NKT細胞を利用したGVHDとGVLの分離Principal Investigator
- Principal Investigator
  
  橋本大吾
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Kyushu University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation Patent

[Journal Article] Calcineurin inhibitor inhibits tolerance induction by suppressing terminal exhaustion of donor T cells after allo-HCT2023
- Author(s)
  Senjo Hajime、Harada Shinpei、Kubota Shimpei I.、Tanaka Yuki、Tateno Takahiro、Zhang Zixuan、Okada Satomi、Chen Xuanzhong、Kikuchi Ryo、Miyashita Naoki、Onozawa Masahiro、Goto Hideki、Endo Tomoyuki、Hasegawa Yuta、Ohigashi Hiroyuki、Ara Takahide、Hasegawa Yoshinori、Murakami Masaaki、Teshima Takanori、Hashimoto Daigo
- Journal Title
  
  Blood
  
  Volume: 142 Issue: 5 Pages: 477-492
- DOI
  10.1182/blood.2023019875
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18296, KAKENHI-PROJECT-21K16259, KAKENHI-PROJECT-22K15435, KAKENHI-PROJECT-23K14551, KAKENHI-PROJECT-21K08409, KAKENHI-PROJECT-20K17366, KAKENHI-PROJECT-20H00502, KAKENHI-PROJECT-23K21439
[Journal Article] Separation of GVL from GVHD -location, location, location2023
- Author(s)
  Teshima Takanori、Hashimoto Daigo
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 14 Pages: 1296663-1296663
- DOI
  10.3389/fimmu.2023.1296663
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08409
[Journal Article] Decreased Paneth cell α-defensins promote fibrosis in a choline-deficient L-amino acid-defined high-fat diet-induced mouse model of nonalcoholic steatohepatitis via disrupting intestinal microbiota2023
- Author(s)
  Nakamura Shunta、Nakamura Kiminori、Yokoi Yuki、Shimizu Yu、Ohira Shuya、Hagiwara Mizu、Song Zihao、Gan Li、Aizawa Tomoyasu、Hashimoto Daigo、Teshima Takanori、Ouellette Andre J.、Ayabe Tokiyoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 3953-3953
- DOI
  10.1038/s41598-023-30997-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08409, KAKENHI-PROJECT-22K19120, KAKENHI-PROJECT-21K15460, KAKENHI-PROJECT-20H04098, KAKENHI-PROJECT-21H02891, KAKENHI-PROJECT-22KJ0054, KAKENHI-PROJECT-20K21610, KAKENHI-PROJECT-22K16009, KAKENHI-PROJECT-23K21439
[Journal Article] Guest editorial: prophylaxis and treatment of relapse after allogeneic hematopoietic stem cell transplantation2022
- Author(s)
  Hashimoto Daigo
- Journal Title
  
  International Journal of Hematology
  
  Volume: 116 Issue: 3 Pages: 307-308
- DOI
  10.1007/s12185-022-03407-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08409
[Journal Article] GVHD: pathophysiology and novel agents2022
- Author(s)
  荒隆英、橋本大吾
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 63 Issue: 9 Pages: 1261-1269
- DOI
  10.11406/rinketsu.63.1261
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08409, KAKENHI-PROJECT-21K16259
[Journal Article] Conditioning Regimens are Associated with Distinct Patterns of Microbiota Injury in Allogeneic Hematopoietic Cell Transplantation2022
- Author(s)
  Shouval Roni、Hashimoto Daigo、et al. (19番目、他26名)
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 29 Issue: 1 Pages: 165-173
- DOI
  10.1158/1078-0432.ccr-22-1254
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08409
[Journal Article] Reactive granulopoiesis depends on T-cell production of IL-17A and neutropenia-associated alteration of gut microbiota2022
- Author(s)
  Chen Xuanzhong、Hashimoto Daigo、Ebata Ko、Takahashi Shuichiro、Shimizu Yu、Shinozaki Ryuga、Hasegawa Yuta、Kikuchi Ryo、Senjo Hajime、Yoneda Kazuki、Zhang Zixuan、Harada Shinpei、Hayase Eiko、Ara Takahide、Ohigashi Hiroyuki、Iwakura Yoichiro、Nakamura Kiminori、Ayabe Tokiyoshi、Teshima Takanori
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 119 Issue: 48 Pages: 1-10
- DOI
  10.1073/pnas.2211230119
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08409, KAKENHI-PROJECT-22K19120, KAKENHI-PROJECT-21K16259, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-20H04098, KAKENHI-PROJECT-21H02891, KAKENHI-PROJECT-22KJ0033, KAKENHI-PROJECT-20K21610, KAKENHI-PROJECT-22K16009, KAKENHI-PROJECT-23K21439
[Journal Article] Gilteritinib enhances graft-versus-leukemia effects against FLT3-ITD mutant leukemia after allogeneic hematopoietic stem cell transplantation2022
- Author(s)
  Zhang Zixuan、Hasegawa Yuta、Hashimoto Daigo、Senjo Hajime、Kikuchi Ryo、Chen Xuanzhong、Yoneda Kazuki、Sekiguchi Tomoko、Kawase Tatsuya、Tsuzuki Hirofumi、Ishio Takashi、Ara Takahide、Ohigashi Hiroyuki、Nakagawa Masao、Teshima Takanori
- Journal Title
  
  Bone Marrow Transplantation
  
  Volume: - Issue: 5 Pages: 775-780
- DOI
  10.1038/s41409-022-01619-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16259, KAKENHI-PROJECT-21K08409, KAKENHI-PROJECT-21H02775, KAKENHI-PROJECT-20K21610, KAKENHI-PROJECT-23K21439
[Journal Article] Intravenous transplantation of amnion-derived mesenchymal stem cells promotes functional recovery and alleviates intestinal dysfunction after spinal cord injury.2022
- Author(s)
  Takamiya S, Kawabori M, Yamazaki K, Yamaguchi S, Tanimori A, Yamamoto K, Ohnishi S, Seki T, Konno K, Tha KK, Hashimoto D, Watanabe M, Houkin K, Fujimura M.
- Journal Title
  
  PLoS One
  
  Volume: 17 Issue: 7 Pages: e0270606-e0270606
- DOI
  10.1371/journal.pone.0270606
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06746, KAKENHI-PROJECT-21K08409, KAKENHI-PROJECT-20K09361
[Journal Article] High CRP-albumin ratio predicts poor prognosis in transplant ineligible elderly patients with newly diagnosed acute myeloid leukemia2022
- Author(s)
  Senjo Hajime、Onozawa Masahiro、Hidaka Daisuke、Yokoyama Shota、Yamamoto Satoshi、Tsutsumi Yutaka、Haseyama Yoshihito、Nagashima Takahiro、Mori Akio、Ota Shuichi、Sakai Hajime、Ishihara Toshimichi、Miyagishima Takuto、Kakinoki Yasutaka、Kurosawa Mitsutoshi、Kobayashi Hajime、Iwasaki Hiroshi、Hashimoto Daigo、et al.
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 8885-8885
- DOI
  10.1038/s41598-022-12813-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08409
[Journal Article] Editorial: Mouse Models of Hematopoietic Stem Cell Transplantation2022
- Author(s)
  Varelias Antiopi、Zhang Ping、Hashimoto Daigo
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 13 Pages: 882592-882592
- DOI
  10.3389/fimmu.2022.882592
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08409
[Journal Article] Novel Insights Into the Mechanism of GVHD-Induced Tissue Damage2021
- Author(s)
  Ara T, Hashimoto D
- Journal Title
  
  Front Immunol
  
  Volume: 12 Pages: 713631-713631
- DOI
  10.3389/fimmu.2021.713631
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08409, KAKENHI-PROJECT-21K16259
[Journal Article] Short-term KRP203 and posttransplant cyclophosphamide for graft-versus-host disease prophylaxis.2020
- Author(s)
  Yokoyama E, Hashimoto D, Hayase E, Ara T, Ogasawara R, Takahashi S, Ohigashi H, Tateno T, Hasegawa Y, Chen X, Teshima T.
- Journal Title
  
  Bone Marrow Transplant.
  
  Volume: 55 Issue: 4 Pages: 787-795
- DOI
  10.1038/s41409-019-0733-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09945, KAKENHI-PROJECT-17K19641, KAKENHI-PROJECT-17H04206
[Journal Article] Microbiota as Predictor of Mortality in Allogeneic Hematopoietic-Cell Transplantation2020
- Author(s)
  Peled Jonathan U.、Gomes Antonio L.C.、Devlin Sean M.、Littmann Eric R.、Taur Ying、Sung Anthony D.、Teshima Takanori、…van den Brink Marcel R.M.
- Journal Title
  
  New England Journal of Medicine
  
  Volume: 382 Issue: 9 Pages: 822-834
- DOI
  10.1056/nejmoa1900623
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04206, KAKENHI-PROJECT-17K09945, KAKENHI-PROJECT-17K19641
[Journal Article] Histological and magnified endoscopic evaluation of villous atrophy in gastrointestinal graft-versus-host disease.2020
- Author(s)
  Matsuda K, Ono S, Tanaka I, Inoue M, Kinowaki S, Ishikawa M, Tsuda M, Yamamoto K, Shimizu Y, Takahashi S, Hayase E, Hashimoto D, Teshima T, Sakamoto N.
- Journal Title
  
  Ann Hematol.
  
  Volume: ー Issue: 5 Pages: 1121-1128
- DOI
  10.1007/s00277-020-03966-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09945
[Journal Article] Ocular instillation of vitamin A-coupled liposomes containing HSP47 siRNA ameliorates dry eye syndrome in chronic GVHD.2019
- Author(s)
  Ohigashi, H., Hashimoto, D., Hayase, E., Takahashi, S., Ara, T., Yamakawa, T., Sugita, J., Onozawa, M., Nakagawa, M., Teshima, T.
- Journal Title
  
  Blood Adv.
  
  Volume: 3 Issue: 7 Pages: 1003-1010
- DOI
  10.1182/bloodadvances.2018028431
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08313, KAKENHI-PROJECT-17H04206, KAKENHI-PROJECT-17K09945, KAKENHI-PROJECT-17K19641
[Journal Article] Lactose drives Enterococcus expansion to promote graft-versus-host disease2019
- Author(s)
  Stein-Thoeringer C. K.、Nichols K. B.、Lazrak A.、Docampo M. D.、Slingerland A. E.、Slingerland J. B.、Teshima T.、…van den Brink M. R. M.
- Journal Title
  
  Science
  
  Volume: 366 Issue: 6469 Pages: 1143-1149
- DOI
  10.1126/science.aax3760
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04206, KAKENHI-PROJECT-17K09945, KAKENHI-PROJECT-17K19641
[Journal Article] Myeloid differentiation factor 88 signaling in donor T cells accelerates graft-versus-host disease2019
- Author(s)
  Matsuoka Satomi、Hashimoto Daigo、Kadowaki Masanori、Ohigashi Hiroyuki、Hayase Eiko、Yokoyama Emi、Hasegawa Yuta、Tateno Takahiro、Chen Xuanzhong、Aoyama Kazutoshi、Oka Hideyo、Onozawa Masahiro、Takeda Kiyoshi、Akashi Koichi、Teshima Takanori
- Journal Title
  
  Haematologica
  
  Volume: 105 Issue: 1 Pages: 226-234
- DOI
  10.3324/haematol.2018.203380
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04206, KAKENHI-PROJECT-17K09945, KAKENHI-PROJECT-17K19641
[Journal Article] The association between the incidence of intestinal graft-vs-host disease and antibiotic use after allogeneic hematopoietic stem cell transplantation2018
- Author(s)
  Hidaka Daisuke、Hayase Eiko、Shiratori Souichi、Hasegawa Yuta、Ishio Takashi、Tateno Takahiro、Okada Kohei、Goto Hideki、Sugita Junichi、Onozawa Masahiro、Nakagawa Masao、Kahata Kaoru、Endo Tomoyuki、Hashimoto Daigo、Teshima Takanori
- Journal Title
  
  Clinical Transplantation
  
  Volume: 32 Issue: 9
- DOI
  10.1111/ctr.13361
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09945, KAKENHI-PROJECT-18K08313, KAKENHI-PROJECT-17K19641, KAKENHI-PROJECT-17H04206
[Journal Article] Essential role of IFN-γ in T cell?associated intestinal inflammation2018
- Author(s)
  Eriguchi Yoshihiro、Nakamura Kiminori、Yokoi Yuki、Sugimoto Rina、Takahashi Shuichiro、Hashimoto Daigo、Teshima Takanori、Ayabe Tokiyoshi、Selsted Michael E.、Ouellette Andre J.
- Journal Title
  
  JCI Insight
  
  Volume: 3 Issue: 18 Pages: 1-18
- DOI
  10.1172/jci.insight.121886
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09945, KAKENHI-PROJECT-17K11661, KAKENHI-PROJECT-17H04206, KAKENHI-PROJECT-18H02788
[Journal Article] Niche signals regulate differentiation and functions of tissue resident macrophages2018
- Author(s)
  橋本大吾
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 59 Issue: 10 Pages: 1886-1894
- DOI
  10.11406/rinketsu.59.1886
- NAID
  130007496929
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-17K09945
[Journal Article] Ruxolitinib protects skin stem cells and maintains skin homeostasis in murine graft-versus-host disease2018
- Author(s)
  Takahashi Shuichiro、Hashimoto Daigo、Hayase Eiko、Ogasawara Reiki、Ohigashi Hiroyuki、Ara Takahide、Yokoyama Emi、Ebata Ko、Matsuoka Satomi、Hill Geoffrey R.、Sugita Junichi、Onozawa Masahiro、Teshima Takanori
- Journal Title
  
  Blood
  
  Volume: 131 Issue: 18 Pages: 2074-2085
- DOI
  10.1182/blood-2017-06-792614
- NAID
  120006626559
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09945
[Journal Article] Vitamin A-coupled liposomes containing siRNA against HSP47 ameliorate skin fibrosis in chronic graft-versus-host disease2018
- Author(s)
  Yamakawa T*, Ohigashi H*, Hashimoto D*, Hayase E, Takahashi S, Miyazaki M, Minomi K, Onozawa M, Niitsu Y, Teshima T (*: equally contributed)
- Journal Title
  
  Blood
  
  Volume: 131 Issue: 13 Pages: 1476-1485
- DOI
  10.1182/blood-2017-04-779934
- NAID
  120006595502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09945
[Journal Article] Intestinal Lymphatic Endothelial Cells Produce R-Spondin32018
- Author(s)
  Ogasawara Reiki、Hashimoto Daigo、Kimura Shunsuke、Hayase Eiko、Ara Takahide、Takahashi Shuichiro、Ohigashi Hiroyuki、Yoshioka Kosuke、Tateno Takahiro、Yokoyama Emi、Ebata Ko、Kondo Takeshi、Sugita Junichi、Onozawa Masahiro、Iwanaga Toshihiko、Teshima Takanori
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 1-9
- DOI
  10.1038/s41598-018-29100-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09945, KAKENHI-PROJECT-17K19641, KAKENHI-PROJECT-17H04206, KAKENHI-PROJECT-16K08457
[Journal Article] Cecum ulcer is a reliable endoscopic finding in cytomegalovirus colitis concomitant with graft-versus-host disease after allogeneic hematopoietic stem cell transplantation2018
- Author(s)
  Matsuda Kana、Ono Shoko、Ishikawa Marin、Miyamoto Shuichi、Abiko Satoshi、Tsuda Momoko、Yamamoto Keiko、Kudo Takahiko、Shimizu Yuichi、Hayase Eiko、Hashimoto Daigo、Teshima Takanori、Matsuno Yoshihiro、Sakamoto Naoya
- Journal Title
  
  Annals of Hematology
  
  Volume: 97 Issue: 5 Pages: 877-883
- DOI
  10.1007/s00277-018-3241-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09945, KAKENHI-PROJECT-16H05282, KAKENHI-PROJECT-17H04206
[Journal Article] Risk factors of human herpesvirus 6 encephalitis/myelitis after allogeneic hematopoietic stem cell transplantation.2017
- Author(s)
  Miyashita N, Endo T, Onozawa M, Hashimoto D, Kondo T, Fujimoto K, Kahata K, Sugita J, Goto H, Matsukawa T, Hashino S, Teshima T.
- Journal Title
  
  Transpl Infect Dis.
  
  Volume: 印刷中 Issue: 3
- DOI
  10.1111/tid.12682
- NAID
  120006470980
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461438
[Journal Article] Graft-versus-host disease in the ovary potentially causes female infertility after allogeneic hematopoietic stem cell transplantation2017
- Author(s)
  Shimoji S, Hashimoto D, Teshima T
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 58 Issue: 7 Pages: 827-834
- DOI
  10.11406/rinketsu.58.827
- NAID
  130005907633
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09945
[Journal Article] R-Spondin1 expands Paneth cells and prevents dysbiosis induced by graft-versus-host disease2017
- Author(s)
  Hayase E, Hashimoto D, Nakamura K, Noizat C, Ogasawara R, Takahashi S, Ohigashi H, Yokoi Y, Sugimoto R, Matsuoka S, Ara T, Yokoyama E, Yamakawa T, Ebata K, Kondo T, Hiramine R, Aizawa T, Ogura Y, Hayashi T, Mori H, Kurokawa K, Tomizuka K, Ayabe T, Teshima T
- Journal Title
  
  J Exp Med
  
  Volume: 214 Issue: 12 Pages: 3507-3518
- DOI
  10.1084/jem.20170418
- NAID
  120006394569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09945, KAKENHI-PROJECT-17K11661
[Journal Article] MALDI-TOF MS in post-transplant bloodstream infections: reliable identification of causative bacteria in the neutropenic phase.2017
- Author(s)
  Kanaya M, Hayashi Y, Hashimoto D, Endo T, Sugita J, Ohigashi H, Hashiguchi J, Matsukawa T, Matsuoka S, Kosugi-Kanaya M, Goto H, Onozawa M, Kahata K, Fujimoto K, Kondo T, Akizawa K, Shibuya H, Shimizu C, Teshima T.
- Journal Title
  
  Bone Marrow Transplant.
  
  Volume: 印刷中 Issue: 5 Pages: 778-780
- DOI
  10.1038/bmt.2016.365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461438
[Journal Article] A leukemogenic kinase, FIP1L1-PDGFRA, and a SUMO E3 ligase, PIAS1, form a positive crosstalk via their enzymatic activities.2017
- Author(s)
  M. Ibata, J. Iwasaki, Y. Fujioka, K. Nakagawa, S. Darmanin, M. Onozawa, D. Hashimoto, Y. Ohba, S. Hatakeyama, T. Teshima and T. Kondo.
- Journal Title
  
  Cancer Sci.
  
  Volume: 108 Issue: 2 Pages: 200-207
- DOI
  10.1111/cas.13129
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01248, KAKENHI-PROJECT-15H04690, KAKENHI-PROJECT-16H06227, KAKENHI-PROJECT-26293041, KAKENHI-PROJECT-26461438, KAKENHI-PROJECT-15K15023, KAKENHI-PROJECT-15KK0290
[Journal Article] Graft-versus-host disease targets ovary and causes female infertility in mice.2017
- Author(s)
  S. Shimoji, D. Hashimoto, H. Tsujigiwa, K. Miyawaki, K. Kato, S. Takahashi, R. Ogasawara, T. Jiromaru, H. Iwasaki, T. Miyamoto, K. Akashi, *T. Teshima
- Journal Title
  
  Blood
  
  Volume: 129 Issue: 9 Pages: 1216-1225
- DOI
  10.1182/blood-2016-07-728337
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-16H06391, KAKENHI-PROJECT-26461438, KAKENHI-PROJECT-15K15358
[Journal Article] Expansion and Activation of CD103(+) Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition.2016
- Author(s)
  Salmon H, Idoyaga J, Rahman A, Leboeuf M, Remark R, Jordan S, Casanova-Acebes M, Khudoynazarova M, Agudo J, Tung N, Chakarov S, Rivera C, Hogstad B, Bosenberg M, Hashimoto D, Gnjatic S, Bhardwaj N, Palucka AK, Brown BD, Brody J, Ginhoux F, Merad M.
- Journal Title
  
  Immunity.
  
  Volume: 44 Issue: 4 Pages: 924-938
- DOI
  10.1016/j.immuni.2016.03.012
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461438
[Journal Article] Reduced-dose methotrexate in combination with tacrolimus was associated with rapid engraftment and recovery from oral mucositis without affecting the incidence of GVHD.2016
- Author(s)
  Matsukawa T, Hashimoto D, Sugita J, Nakazawa S, Matsushita T, Kashiwazaki H, Goto H, Onozawa M, Kahata K, Fujimoto K, Endo T, Kondo T, Hashino S, Yamazaki Y, Teshima T.
- Journal Title
  
  Int J Hematol.
  
  Volume: 104 Issue: 1 Pages: 117-124
- DOI
  10.1007/s12185-016-1996-0
- NAID
  120006313418
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461438
[Journal Article] The Mononuclear Phagocyte System in Organ Transplantation.2016
- Author(s)
  Ochando J, Kwan WH, Ginhoux F, Hutchinson JA, Hashimoto D, Collin M
- Journal Title
  
  American Journal of Transplantation
  
  Volume: 16(4) Issue: 4 Pages: 1053-1069
- DOI
  10.1111/ajt.13627
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461438
[Journal Article] Cytogenetically Unrelated Clones in Acute Myeloid Leukemia Showing Different Responses to Chemotherapy.2016
- Author(s)
  Kasahara K, Onozawa M, Miyashita N, Yokohata E, Yoshida M, Kanaya M, Kosugi-Kanaya M, Takemura R, Takahashi S, Sugita J, Shigematsu A, Takahata M, Fujisawa S, Hashimoto D, Fujimoto K, Endo T, Kondo T, Teshima T
- Journal Title
  
  Case Rep Hematol.
  
  Volume: 2016 Pages: 1-5
- DOI
  10.1155/2016/2373902
- NAID
  120005822530
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461438
[Journal Article] Key players in intestinal GVHD2015
- Author(s)
  橋本大吾, 豊嶋崇徳
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 56 Issue: 7 Pages: 807-814
- DOI
  10.11406/rinketsu.56.807
- NAID
  130005093106
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461438
[Journal Article] α-Mannan induces Th17-mediated pulmonary graft-versus-host disease in mice.2015
- Author(s)
  Uryu H, Hashimoto D, Kato K, Hayase E, Matsuoka S, Ogasawara R, Takahashi S, Maeda Y, Iwasaki H, Miyamoto T, Saijo S, Iwakura Y, Hill GR, Akashi K, Teshima T.:
- Journal Title
  
  Blood
  
  Volume: 125 Issue: 19 Pages: 3014-23
- DOI
  10.1182/blood-2014-12-615781
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22130002, KAKENHI-PROJECT-25253069, KAKENHI-PROJECT-26461438, KAKENHI-PROJECT-15K15365, KAKENHI-PROJECT-25461424, KAKENHI-PROJECT-26293094, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
[Journal Article] Requirement for Innate Immunity and CD90+ NK1.1- Lymphocytes to Treat Established Melanoma with Chemo-Immunotherapy.2015
- Author(s)
  Moskalenko M, Pan M, Fu Y, de Moll EH, Hashimoto D, Mortha A, Leboeuf M, Jayaraman P, Bernardo S, Sikora AG, Wolchok J, Bhardwaj N, Merad M, Saenger Y
- Journal Title
  
  Cancer Immunology Research
  
  Volume: 3 Issue: 3 Pages: 296-304
- DOI
  10.1158/2326-6066.cir-14-0120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461438
[Journal Article] Decreased secretion of Paneth cell α-defensins in graft-versus-host disease.2015
- Author(s)
  Eriguchi Y, Nakamura K, Hashimoto D, Shimoda S, Shimono N, Akashi K, Ayabe T, Teshima T
- Journal Title
  
  Transplant Infectious Disease
  
  Volume: 17 Issue: 5 Pages: 702-706
- DOI
  10.1111/tid.12423
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461438, KAKENHI-PROJECT-26462831
[Journal Article] Crosstalk between muscularis macrophages and enteric neurons regulates gastrointestinal motility.2014
- Author(s)
  Muller PA, Koscso B, Rajani GM, Stevanovic K, Berres ML, Hashimoto D, Mortha A, Leboeuf M, Li XM, Mucida D, Stanley ER, Dahan S, Margolis KG, Gershon MD, Merad M, Bogunovic M
- Journal Title
  
  Cell
  
  Volume: 158 Issue: 2 Pages: 300-313
- DOI
  10.1016/j.cell.2014.04.050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461438
[Journal Article] Allogeneic hematopoietic stem cell transplantation following reduced-intensity conditioning for mycosis fungoides and Sezary syndrome.2014
- Author(s)
  Shiratori S, Fujimoto K, Nishimura M, Hatanaka KC, Kosugi-Kanaya M, Okada K, Sugita J, Shigematsu A, Hashimoto D, Endo T, Kondo T, Abe R, Hashino S, Matsuno Y, Shimizu H, Teshima T.
- Journal Title
  
  Hematol Oncol
  
  Volume: Epub Ahead of Print Issue: 1 Pages: 9-16
- DOI
  10.1002/hon.2162
- NAID
  120005981361
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590441, KAKENHI-PROJECT-24790341, KAKENHI-PROJECT-25293217, KAKENHI-PROJECT-25670443, KAKENHI-PROJECT-25860775, KAKENHI-PROJECT-26461438, KAKENHI-PROJECT-16K08683
[Journal Article] マクロファージは末梢組織でも自己増殖する！？2014
- Author(s)
  橋本大吾
- Journal Title
  
  炎症と免疫
  
  Volume: 22 Pages: 411-415
- Data Source
  KAKENHI-PROJECT-26461438
[Journal Article] Stenotrophomonas maltophilia infection during allogeneic hematopoietic stem cell transplantation: a single-center experience2014
- Author(s)
  Shiratori S, Wakasa K, Okada K, Sugita J, Akizawa K, Shigematsu A, Hashimoto D, Fujimoto K, Endo T, Kondo T, Shimizu C, Hashino S, Teshima T
- Journal Title
  
  Clin Transplant
  
  Volume: 28(6) Issue: 6 Pages: 656-661
- DOI
  10.1111/ctr.12356
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293217, KAKENHI-PROJECT-25670443, KAKENHI-PROJECT-25860775, KAKENHI-PROJECT-26461438
[Journal Article] Bone Marrow Graft-versus-Host Disease: Evaluation of Its Clinical Impact on Disrupted Hematopoiesis after Allogeneic Hematopoietic Stem Cell Transplantation2014
- Author(s)
  Souichi Shiratori, Mizuha Kosugi-Kanaya, Satoshi Ueha, Junichi Sugita1, Akio Shigematsu, Takeshi Kondo, Daigo Hashimoto, Katsuya Fujimoto, Tomoyuki Endo, Mitsufumi Nishio, Satoshi Hashino, Yoshihiro Matsuno, Kouji Matsushima, Junji Tanaka, Masahiro Imamura, Takanori Teshima
- Journal Title
  
  Biol Blood Marrow Transplant
  
  Volume: 20 Issue: 4 Pages: 495-500
- DOI
  10.1016/j.bbmt.2013.12.568
- NAID
  120005427744
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24659216, KAKENHI-PROJECT-25293113, KAKENHI-PROJECT-25293217, KAKENHI-PROJECT-25460491, KAKENHI-PROJECT-25670443, KAKENHI-PROJECT-25860775, KAKENHI-PROJECT-26461438
[Journal Article] FIP1L1 presence in FIP1L1-RARA or FIP1L1-PDGFRA differentially contributes to the pathogenesis of distinct types of leukemia2014
- Author(s)
  Junko Iwasaki, Takeshi Kondo, Stephanie Darmanin, Makoto Ibata, Masahiro Onozawa, Daigo Hashimoto, Naoya Sakamoto and Takanori Teshima
- Journal Title
  
  Annals of Hematology
  
  Volume: 未定 Issue: 9 Pages: 1473-1482
- DOI
  10.1007/s00277-014-2085-1
- NAID
  120005656326
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461404, KAKENHI-PROJECT-26461438
[Patent] フェロトーシス阻害剤を用いたキメラ抗原受容体遺伝子導入T細胞における過酸化脂質の低減方法2023
- Inventor(s)
  豊嶋崇徳, 橋本大吾, 原田晋平
- Industrial Property Rights Holder
  豊嶋崇徳, 橋本大吾, 原田晋平
- Industrial Property Rights Type
  特許
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-21K08409
[Presentation] GVHDの診断と治療2023
- Author(s)
  橋本大吾
- Organizer
  第46回日本造血免疫細胞療法学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K08409
[Presentation] The role of microbiota in immunity and hematopoiesis after HSCT2023
- Author(s)
  Daigo Hashimoto
- Organizer
  28th Annual Meeting of Asia-Pacific Blood and Marrow Transplantation Group
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08409
[Presentation] Delayed Initiation of Calcineurin Inhibitor Is Critical for Tolerance Induction By Posttransplant Cyclophosphamide2023
- Author(s)
  Hajime Senjo, Daigo Hashimoto, Satomi Okada, Shimpei I Kubota, Ayumu Ito, Takashi Tanaka, Yumika Saito, Toru Miyajima, Wenyu Li, Zixuan Zhang, Shinpei Harada, Yuta Hasegawa, Hiroyuki Ohigashi, Takahide Ara, Yoshinori Hasegawa, Yoshihiro Inamoto, Masaaki Murakami, Takahiro Fukuda, Takanori Teshima
- Organizer
  65th ASH Annual Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08409
[Presentation] 分子標的薬による移植片対白血病効果の促進2023
- Author(s)
  橋本大吾
- Organizer
  第46回日本造血免疫細胞療法学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K08409
[Presentation] Ferroptosis Inhibition Generates TCF-1+ CAR-T Cells with Enhanced Persistence and Cytotoxicity2023
- Author(s)
  Shinpei Harada1, Daigo Hashimoto, Yumika Saito, Toru Miyajima, Wenyu Li, Hajime Senjo, Zixuan Zhang, Ryo Kikuchi, Masahiro Chiba, Hiroyuki Ohigashi, Takahide Ara, Masao Nakagawa, Takanori Teshima
- Organizer
  65th ASH Annual Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08409
[Presentation] Calcineurin Inhibitors Inhibit Tolerance Induction By Suppressing Terminal Dierentiation of Donor Exhausted T Cells after Allogeneic SCT2022
- Author(s)
  Hajime Senjo, Daigo Hashimoto, Shinpei Kubota, Yuki Tanaka, Shinpei Harada , Kazuki Yoneda, Zixuan Zhang, Xuanzhong Chen, Ryo Kikuchi, Yuta Hasegawa, Hiroyuki Ohigashi, Takahide Ara, Yoshinori Hasegawa, Masaaki Murakami, DVM., Ph.D. and Takanori Teshima
- Organizer
  64th ASH Annual Meeting and Exposition
- Data Source
  KAKENHI-PROJECT-21K08409
[Presentation] GVHD Targets Organoid-forming Biliary Epithelial Stem Cells via a TGF-b-Dependent Manner2022
- Author(s)
  Yuta Hasegawa, Daigo Hashimoto, Ryo Kikuchi, Zixuan Zhang, Hajime Senjo, Tomoko Sekiguchi, Eiko Hayase, Takahiro Tateno, Emi Yokoyama, Shuichiro Takahashi, Xuanzhong Chen, Kazuki Yoneda, Hiroyuki Ohigashi, Takahide Ara, and Takanori Teshima
- Organizer
  第84回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08409
[Presentation] Intercellular Mitochondrial Transfer Enhances Metabolic Fitness and Anti-Tumor Effects of CAR T Cells2022
- Author(s)
  Shinpei Harada, Daigo Hashimoto, Hajime Senjo, Kazuki Yoneda, Zixuan Zhang, Xuanzhong Chen, Ryo Kikuchi, Masahiro Chiba, Hiroyuki Ohigashi, Takahide Ara, Masao Nakagawa, Masashi Suganuma, Rick C. Tsai, and Takanori Teshima
- Organizer
  64th ASH Annual Meeting and Exposition
- Data Source
  KAKENHI-PROJECT-21K08409
[Presentation] Gvhd Targets Organoid-Forming Biliary Epithelial Stem Cells Via a TGF-β-Dependent Manner2021
- Author(s)
  Yuta Hasegawa, Daigo Hashimoto, Ryo Kikuchi, Zixuan Zhang, Hajime Senjo, Tomoko Sekiguchi, Eiko Hayase, Takahiro Tateno, Emi Yokoyama, Shuichiro Takahashi, Xuanzhong Chen, Kazuki Yoneda, Hiroyuki Ohigashi, Takahide Ara, Takanori Teshima
- Organizer
  The 63rd ASH Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08409
[Presentation] Intestinal dysbiosis and GVHD: preclinical and clinical findings2021
- Author(s)
  Daigo Hashimoto
- Organizer
  The International Congress of BMT 2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08409
[Presentation] Post-transplant enterococcus mono-domination is a risk of acute Graft-versus- Host disease2020
- Author(s)
  Shuichiro Takahashi、Daigo Hashimoto、Souichi Shiratori、Junichi Sugita、Tomoyuki Endo、 Takanori Teshima
- Organizer
  第42回日本造血細胞移植学会総会
- Data Source
  KAKENHI-PROJECT-17K09945
[Presentation] IRAK4 阻害薬はドナー T 細胞の MyD88 シグナルを阻害して同種造血幹細胞移植後の GvHD を軽減する2020
- Author(s)
  松岡里湖、橋本大吾、門脇賢典、長谷川裕太、大東寛幸、早瀬英子、横山絵美、立野貴大、青山一利、岡英世、小野澤真弘、竹田潔、赤司浩一、豊嶋崇徳
- Organizer
  第42回日本造血細胞移植学会総会
- Data Source
  KAKENHI-PROJECT-17K09945
[Presentation] HSP47 siRNA 含有ビタミン A 結合リポソーム点眼は慢性GVHD による涙腺線維化とドライアイを改善する2020
- Author(s)
  大東寛幸、橋本大吾、高橋秀一郎、荒隆英、山川知宏、早瀬英子、杉田純一、小野澤真弘、中川雅夫、豊嶋崇徳
- Organizer
  第42回日本造血細胞移植学会総会
- Data Source
  KAKENHI-PROJECT-17K09945
[Presentation] A novel graft-versus-host disease prophylaxis with selective S1P1 agonist, KRP203 with posttransplant cyclophosphamide2020
- Author(s)
  Emi Yokoyama、Daigo Hashimoto、Eiko Hayase、Takahide Ara、Reiki Ogasawara、 Tomohiro Yamakawa、Shuichiro Takahashi、Hiroyuki Ohigashi、Takahiro Tateno、 Yuta Hasegawa、Xuanzhong Chen、Takanori Teshima
- Organizer
  第42回日本造血細胞移植学会総会
- Data Source
  KAKENHI-PROJECT-17K09945
[Presentation] GVHD new insight of pathogenesis2019
- Author(s)
  Daigo Hashimoto
- Organizer
  第81回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09945
[Presentation] Crosstalk between microbiota and host immune system affects the outcomes of hematopoietic stem cell transplantation2018
- Author(s)
  Hashimoto Daigo
- Organizer
  The 7th Global Network Forum on Infection and Immunity
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09945
[Presentation] ニッチ機能による組織常在マクロファージの分化・維持・多様化の制御,2018
- Author(s)
  Hashimoto Daigo
- Organizer
  第80回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09945
[Presentation] HSP47 siRNA含有ビタミンA結合リポソームは慢性移植片対宿主病の皮膚線維化を改善する2018
- Author(s)
  山川知宏, 橋本大吾, 早瀬英子, 高橋秀一郎, 大東寛幸, 新津洋司郎, 豊嶋崇徳
- Organizer
  第40回日本造血細胞移植学会総会
- Data Source
  KAKENHI-PROJECT-17K09945
[Presentation] Gastric stem cells are targeted in upper gastrointestinal GVHD.2017
- Author(s)
  Hayase E, Hashimoto D, Takahashi S, Ohigashi H, Takahiro T, Ara T, Yokoyama E, Teshima T.
- Organizer
  59th ASH Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09945
[Presentation] Intestinal microbiota play a critical role in neutrophil engraftment posttransplant and recovery after chemotherapy by stimulating T cell production of IL-17A.2017
- Author(s)
  Ebata K, Hashimoto D, Takahashi S, Hayase E, Ogasawara R, Teshima T.
- Organizer
  59th ASH Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09945
[Presentation] R-spondin1 promotes Panted cell growth, maintains intestinal microbial ecology, and ameliorates GVHD.2016
- Author(s)
  Hayase E, Hashimoto D, Nakamura K, Ogura Y, Hayashi T, Kurokawa K, Ayabe T, Teshima T.
- Organizer
  The 7th JSH International Symposium
- Place of Presentation
  淡路夢舞台国際会議場 (兵庫県淡路市)
- Year and Date
  2016-05-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461438
[Presentation] マクロファージ研究の最前線 (マクロファージの分化・維持・可塑性に関して)2016
- Author(s)
  橋本大吾
- Organizer
  第26回日本樹状細胞研究会
- Place of Presentation
  ホテル日航熊本 (熊本県熊本市)
- Year and Date
  2016-09-02
- Invited
- Data Source
  KAKENHI-PROJECT-26461438
[Presentation] 急性 GVHD 予防における短期メトトレキセート投与量の検討2016
- Author(s)
  松川敏大, 杉田純一, 中澤誠多朗, 阿部貴恵, 柏崎晴彦, 大東寛幸, 金谷穣, 後藤秀樹, 小野澤真弘, 橋本大吾, 加畑馨, 藤本勝也, 遠藤知之, 近藤健, 山崎裕, 豊嶋崇徳
- Organizer
  第38回日本造血細胞移植学会総会
- Place of Presentation
  名古屋国際会議場 (名古屋市)
- Year and Date
  2016-03-03
- Data Source
  KAKENHI-PROJECT-26461438
[Presentation] Topical ruxolitinib protects LGR5+ stem cells in the hair follicle and ameliorates skin graft- versus-host disease.2016
- Author(s)
  Takahashi S, Hashimoto D, Hayase E, Teshima T
- Organizer
  2016 BMT Tandem Meetings
- Place of Presentation
  Hawaii Convention Center (Honolulu, USA)
- Year and Date
  2016-02-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461438
[Presentation] LGR5+ skin stem cells are targeted in GVHD and topical ruxolitinib protects them against GVHD2016
- Author(s)
  高橋秀一郎, 橋本大吾, 早瀬英子, 豊嶋崇徳
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜 (神奈川県横浜市)
- Year and Date
  2016-10-14
- Data Source
  KAKENHI-PROJECT-26461438
[Presentation] Vitamin A-Coupled Liposomes Carrying siRNA Against HSP47 Ameliorate Skin Fibrosis in Chronic Graft-Versus-Host Disease2016
- Author(s)
  Yamakawa T, Hashimoto D, Hayase E, Takahashi S, Teshima T
- Organizer
  58th ASH Annual Meeting
- Place of Presentation
  San Diego, USA, San Diego Convention Center
- Year and Date
  2016-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461438
[Presentation] R-spondin1 promotes Paneth cell growth, maintains intestinal microbial ecology, and ameliorates GvHD.2015
- Author(s)
  Hayase E, Hashimoto D, Nakamura K, Ogura Y, Hayashi T, Kurokawa K, Ayabe T, Teshima T
- Organizer
  57th ASH Annual Meeting
- Place of Presentation
  Orange County Convention Center (Orlando, USA)
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461438
[Presentation] CSF-1/CSF-2による炎症性疾患制御
- Author(s)
  橋本大吾, Arthur Mortha, 豊嶋崇徳, Miriam Merad
- Organizer
  第79回日本インターフェロンサイトカイン学会学術集会
- Place of Presentation
  北海道大学医学部学友会館フラテホール (札幌市)
- Year and Date
  2014-06-19 – 2014-06-20
- Data Source
  KAKENHI-PROJECT-26461438
[Presentation] Graft-Versus-Host Disease Targets Granulosa Cell of Ovarian Follicle and Causes Infertility after Allogeneic Hematopoietic Stem Cell Transplantation.
- Author(s)
  Shimoji S, Hashimoto D, Kato K, Tujigiwa H, Akashi K, Teshima T
- Organizer
  2015 BMT Tandem Meetings
- Place of Presentation
  Manchester Grand Hyatt (San Diego, USA)
- Year and Date
  2015-02-11 – 2015-02-15
- Data Source
  KAKENHI-PROJECT-26461438
[Presentation] Tissue Resident Macrophages Self-maintain Locally Throughout Adult Life with Minimal Contribution from Circulating Monocytes.
- Author(s)
  Hashimoto D
- Organizer
  The 22nd International Symposium on Molecular Cell Biology of Macrophages
- Place of Presentation
  神戸商工会議所 (神戸市)
- Year and Date
  2014-06-02 – 2014-06-03
- Invited
- Data Source
  KAKENHI-PROJECT-26461438
[Presentation] Key players in intestinal GVHD.
- Author(s)
  Hashimoto D, Teshima T
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場 (大阪市)
- Year and Date
  2014-10-31 – 2014-11-02
- Invited
- Data Source
  KAKENHI-PROJECT-26461438
[Presentation] Graft-Versus-Host Disease targets ovary and causes infertility after allo-HSCT
- Author(s)
  Shimoji S, Kato K, Tujigiwa H, Eriguchi Y, Uryu H, Takashima S, Hashimoto D, Miyamoto T, Iwasaki H, Akashi K, Teshima T
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場 (大阪市)
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-26461438

1. NAKAGAWA Masao

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. HATANAKA Yutaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. UEHA Satoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 赤司浩一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 豊嶋崇徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
6. 松野吉宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 荒隆英

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 松島綱治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 近藤健

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 今野幸太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 大場雄介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 宮本敏浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hashimoto Daigo 橋本 大吾

橋本 大吾 ハシモト ダイゴ

Research Projects

Research Products

Co-Researchers

Development of a novel transplantation method targeting the epigenetics of T cells, leukemia Cells, and epithelial cellsPrincipal Investigator

Principal Investigator

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Liver organoid-based study of macrophage-induced injury of liver stem cells in GVHDPrincipal Investigator

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Development of a novel therapy for chronic GVHD targeting a macrophage-myofibroblast axis in fibrotic processPrincipal Investigator

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Reconstitution of mononuclear phagocyte system following allogeneic hematopoietic stem cell transplantationPrincipal Investigator

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NKT細胞を利用したGVHDとGVLの分離Principal Investigator

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[Journal Article] Calcineurin inhibitor inhibits tolerance induction by suppressing terminal exhaustion of donor T cells after allo-HCT2023

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[Journal Article] Separation of GVL from GVHD -location, location, location2023

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[Journal Article] Decreased Paneth cell α-defensins promote fibrosis in a choline-deficient L-amino acid-defined high-fat diet-induced mouse model of nonalcoholic steatohepatitis via disrupting intestinal microbiota2023

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[Journal Article] Guest editorial: prophylaxis and treatment of relapse after allogeneic hematopoietic stem cell transplantation2022

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[Journal Article] GVHD: pathophysiology and novel agents2022

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[Journal Article] Conditioning Regimens are Associated with Distinct Patterns of Microbiota Injury in Allogeneic Hematopoietic Cell Transplantation2022

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[Journal Article] Reactive granulopoiesis depends on T-cell production of IL-17A and neutropenia-associated alteration of gut microbiota2022

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[Journal Article] Gilteritinib enhances graft-versus-leukemia effects against FLT3-ITD mutant leukemia after allogeneic hematopoietic stem cell transplantation2022

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[Journal Article] Intravenous transplantation of amnion-derived mesenchymal stem cells promotes functional recovery and alleviates intestinal dysfunction after spinal cord injury.2022

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Hashimoto Daigo 橋本大吾

橋本大吾ハシモトダイゴ