Amano Takanori 天野孝紀

… Alternative Names

天野孝紀アマノタカノリ

AMANO Takanori 天野孝紀

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Researcher Number	20419849
Other IDs	https://orcid.org/0000-0002-0213-4745
Affiliation (Current)	2025: 国立研究開発法人理化学研究所, バイオリソース研究センター, チームディレクター
Affiliation (based on the past Project Information) *help	2025: 国立研究開発法人理化学研究所, バイオリソース研究センター, チームリーダー 2023: 国立研究開発法人理化学研究所, バイオリソース研究センター, チームリーダー 2019 – 2021: 国立研究開発法人理化学研究所, バイオリソース研究センター, チームリーダー 2017: 国立遺伝学研究所, 系統生物研究センター, 特任研究員 2017: 国立遺伝学研究所, 系統生物研究センター, 研究員 … More 2016 – 2017: 国立遺伝学研究所, 系統生物研究センター, 助教 2014: 国立遺伝学研究所, 系統生物研究センター, 助教 2010 – 2011: 国立遺伝学研究所, 系統生物研究センター, 特任研究員 Less
Review Section/Research Field	Principal Investigator Basic Section 42040:Laboratory animal science-related / Genetics/Chromosome dynamics / Developmental biology Except Principal Investigator Transformative Research Areas, Section (IV) / Genetics/Chromosome dynamics / Genetics/Genome dynamics
Keywords	Principal Investigator ゲノム / マウス / 遺伝子発現 / 疾患モデル / バリアント / ヒルシュスプルング病 / 形態形成 / インシュレーター / 遺伝子発現制御 / 染色体動態 / エンハンサー / 遺伝子発現調節 … More Except Principal Investigator … More 発生・分化 / ゲノム / 遺伝学 / マウス / 遺伝子発現制御 / 継世代効果 / 精子エピゲノム / 疾患表現型 / ミトコンドリア機能 / 進化・分化 / 発生制御 / 進化 / 発現制御 / シス制御配列の進化 / Shh / シジ制御配列の進化 / 発生生物学 / エンハンサー / 染色体高次構造 Less

Adaptation to space environment and transgenerational effects explored using mitochondrial dysfunction model mice
- Principal Investigator
  
  吉田圭介
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (IV)
- Research Institution
  Nippon Medical School
マウス亜種間発現差を利用したシス多型の探索Principal Investigator
- Principal Investigator
  
  天野孝紀
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Institute of Physical and Chemical Research
Modeling complex diseases using mouse subspecies strainsPrincipal Investigator
- Principal Investigator
  
  Amano Takanori
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Institute of Physical and Chemical Research
Enhancer-sharing and insulation via chromosomal dynamicsPrincipal Investigator
- Principal Investigator
  
  Amano Takanori
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Genetics/Chromosome dynamics
- Research Institution
  National Institute of Genetics
Cis-regulatory polymorphism responsible for allele-expression-bias that contributes to mouse phenotype
- Principal Investigator
  
  Toshihiko Shiroishi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Genetics/Chromosome dynamics
- Research Institution
  National Institute of Genetics
Transcriptional regulation of Shh via chromosomal dynamics
- Principal Investigator
  
  SHIROISHI Toshihio
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Genetics/Genome dynamics
- Research Institution
  National Institute of Genetics
Screening of factors binding to the Shh limb enhancerPrincipal Investigator
- Principal Investigator
  
  AMANO Takanori
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Developmental biology
- Research Institution
  National Institute of Genetics

All 2024 2023 2022 2021 2020 2018 2017 2016 2014 2013 2011 2010 Other

All Journal Article Presentation Book

[Book] 先端の分析法第2版2022
- Author(s)
  澤田嗣郎、小澤岳昌、北森武彦、中村洋、藤浪眞紀、宮村一夫、石丸洋一郎、浦野泰照、加地範匡、坂真智子、鈴木茂、瀬藤光利、宗林由樹、馬場嘉信、船津公人、本田暁紀、末永智一、宮野博、本山晃、天野孝紀
- Total Pages
  1072
- Publisher
  エヌ・ティー・エス
- ISBN
  9784860437374
- Data Source
  KAKENHI-PROJECT-19K06477
[Book] 生物の科学遺伝 2014年5月号2014
- Author(s)
  天野孝紀、城石俊彦
- Total Pages
  300
- Publisher
  株式会社　エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-24247002
[Book] 生物機能モデルと新しいリソース・リサーチツール2011
- Author(s)
  天野孝紀, 他
- Publisher
  株式会社エル・アイ・シー
- Data Source
  KAKENHI-PROJECT-22770224
[Book] 生物機能モデルと新しいリソース・リサーチツール第I部生物機能モデルの作製と利用第1章発生・形態形成第5節中胚葉性器官形成第4項四肢2011
- Author(s)
  天野孝紀
- Publisher
  株式会社エル・アイ・シー
- Data Source
  KAKENHI-PROJECT-22770224
[Journal Article] Inter-subspecies mouse F1 hybrid embryonic stem cell lines newly established for studies of allelic imbalance in gene expression2024
- Author(s)
  SAITO Ayaka、TAHARA Ryosuke、HIROSE Michiko、KADOTA Masayo、HASEGAWA Ayumi、KONDO Shinji、KATO Hidemasa、AMANO Takanori、YOSHIKI Atsushi、OGURA Atsuo、KIYOSAWA Hidenori
- Journal Title
  
  Exp. Anim.
  
  Volume: 73 Issue: 3 Pages: 310-318
- DOI
  10.1538/expanim.24-0002
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K05610, KAKENHI-PLANNED-19H05758
[Journal Article] The shh limb enhancer is activated in patterned limb regeneration but not in hypomorphic limb regeneration in Xenopus laevis2023
- Author(s)
  Tada Reimi、Higashidate Takuya、Amano Takanori、Ishikawa Shoma、Yokoyama Chifuyu、Kobari Suzu、Nara Saki、Ishida Koshiro、Kawaguchi Akane、Ochi Haruki、Ogino Hajime、Yakushiji-Kaminatsui Nayuta、Sakamoto Joe、Kamei Yasuhiro、Tamura Koji、Yokoyama Hitoshi
- Journal Title
  
  Developmental Biology
  
  Volume: 500 Pages: 22-30
- DOI
  10.1016/j.ydbio.2023.05.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06195, KAKENHI-PROJECT-22K06233, KAKENHI-PROJECT-23K05610, KAKENHI-PROJECT-20H05702, KAKENHI-PROJECT-23K26510
[Journal Article] Gene regulatory landscape of the sonic hedgehog locus in embryonic development2020
- Author(s)
  Amano Takanori
- Journal Title
  
  Development, Growth & Differentiation
  
  Volume: 62 Issue: 5 Pages: 334-342
- DOI
  10.1111/dgd.12668
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06477
[Journal Article] Upstream Enhancer Elements of Shh Regulate Oral and Dental Patterning2018
- Author(s)
  Seo H.、Amano T.、Seki R.、Sagai T.、Kim J.、Cho S.W.、Shiroishi T.
- Journal Title
  
  Journal of Dental Research
  
  Volume: - Issue: 9 Pages: 1-9
- DOI
  10.1177/0022034518758642
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18589
[Journal Article] Two Types of Etiological Mutation in the Limb-Specific Enhancer of Shh2017
- Author(s)
  Amano Takanori、Sagai Tomoko、Seki Ryohei、Shiroishi Toshihiko
- Journal Title
  
  G3
  
  Volume: 7 Issue: 9 Pages: 2991-2998
- DOI
  10.1534/g3.117.044669
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K18589
[Journal Article] SHH signaling directed by two oral epithelium-specific enhancers controls tooth and oral development2017
- Author(s)
  Sagai Tomoko、Amano Takanori、Maeno Akiteru、Kiyonari Hiroshi、Seo Hyejin、Cho Sung-Won、Shiroishi Toshihiko
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1
- DOI
  10.1038/s41598-017-12532-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02412, KAKENHI-PROJECT-16K18589, KAKENHI-PROJECT-17H00440
[Journal Article] Evolution of Shh endoderm enhancers during morphological transition from ventral lungs to dorsal gas bladder2017
- Author(s)
  Tomoko Sagai, Takanori Amano, Akiteru Maeno, Tetsuaki Kimura, Masatoshi Nakamoto, Yusuke Takehana, Kiyoshi Naruse, Norihiro Okada, Hiroshi Kiyonari & Toshihiko Shiroishi
- Journal Title
  
  Nature Communications 8
  
  Volume: 14300 Issue: 1
- DOI
  10.1038/ncomms14300
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H02412
[Journal Article] Enhancer adoption caused by genomic insertion elicits interdigitalShhexpression and syndactyly in mouse2017
- Author(s)
  Mouri Kousuke、Sagai Tomoko、Maeno Akiteru、Amano Takanori、Toyoda Atsushi、Shiroishi Toshihiko
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 115 Issue: 5 Pages: 1021-1026
- DOI
  10.1073/pnas.1713339115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19411, KAKENHI-PROJECT-17K15162, KAKENHI-PROJECT-15J06985, KAKENHI-PROJECT-16K18589, KAKENHI-PROJECT-17H00440
[Journal Article] A novel regulatory element for Shh expression in the lung and gut of mouse embryos2014
- Author(s)
  Tsukiji Nagaharu, Takanori Amano and Toshihiko Shiroishi
- Journal Title
  
  Mech. Dev.
  
  Volume: 131 Pages: 127-136
- DOI
  10.1016/j.mod.2013.09.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24247002
[Journal Article] The Hand2 gene dosage effect in developmental defects and human congenital disorders2014
- Author(s)
  Masaru Tamura, Takanori Amano and Toshihiko Shiroishi
- Journal Title
  
  Curr. Top. Dev. Biol.
  
  Volume: 110 Pages: 129-152
- DOI
  10.1016/b978-0-12-405943-6.00003-8
- ISBN
  9780124059436
- Data Source
  KAKENHI-PROJECT-24247002
[Journal Article] マウスゲノムを読み解くための新しい文法書2013
- Author(s)
  天野孝紀
- Journal Title
  
  生物の科学　遺伝
  
  Volume: 67巻 Pages: 141-144
- Data Source
  KAKENHI-PROJECT-24247002
[Journal Article] Prx-1 Expression in Xenopus laevis Scarless Skin-Wound Healing and Its Resemblance to Epimorphic Regeneration2011
- Author(s)
  Yokoyama H
- Journal Title
  
  J Invest Dermatol
  
  Volume: 131 Issue: 12 Pages: 477-485
- DOI
  10.1038/jid.2011.223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247002, KAKENHI-ORGANIZER-22124001, KAKENHI-PLANNED-22124005, KAKENHI-PROJECT-22770224
[Journal Article] Anterior shift in gene expression precedes anteriormost digit formation in amniote limbs Development2010
- Author(s)
  Uejima A, Amano T, Nomura N, Noro M, Yasue T, Shiroishi T, Ohta K, Yokoyama H, Tamura K.
- Journal Title
  
  Growth and Differentiation
  
  Volume: Vol.52 Issue: 2 Pages: 223-234
- DOI
  10.1111/j.1440-169x.2009.01161.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22770224
[Presentation] Development of disease model mice reflecting human genotypes and pathologies2023
- Author(s)
  Amano Takanori
- Organizer
  AFLAS2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05610
[Presentation] ヒルシュスプルング病モデルマウスを用いた包括的な表現型解析2023
- Author(s)
  天野孝紀、吉田圭介、田村勝
- Organizer
  第63回日本先天異常学会学術集会
- Data Source
  KAKENHI-PROJECT-23K05610
[Presentation] マウスEdnrb遺伝子座のトランスポゾン挿入変異による白斑発症メカニズム2021
- Author(s)
  天野孝紀、綾部信哉、吉田圭介
- Organizer
  第61回日本先天異常学会学術集会
- Data Source
  KAKENHI-PROJECT-19K06477
[Presentation] A novel CRE positively and negatively influences the expression of Shh and its bystander genes2017
- Author(s)
  天野孝紀
- Organizer
  第50回日本発生生物学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18589
[Presentation] マウス亜種系統間の胃形態差に寄与するShh遺伝子のシス多型2016
- Author(s)
  天野孝紀、城石俊彦
- Organizer
  日本遺伝学会第88回大会
- Place of Presentation
  静岡県三島市
- Year and Date
  2016-09-07
- Data Source
  KAKENHI-PROJECT-15H02412
[Presentation] マウス亜種系統間の胃形態差に寄与するShh遺伝子のシス多型2016
- Author(s)
  天野孝紀、城石俊彦
- Organizer
  日本遺伝学会第88回大会
- Place of Presentation
  三島
- Year and Date
  2016-09-07
- Data Source
  KAKENHI-PROJECT-16K18589
[Presentation] Identification of a novel regulatory element for Shh expression in the mouse lung and gut2013
- Author(s)
  Takanori Amano, Nagaharu Tsukiji, Toshihiko Shiroishi
- Organizer
  第46回日本発生生物学会大会（APDBN共催）
- Place of Presentation
  松江
- Data Source
  KAKENHI-PROJECT-24247002
[Presentation] Evolutionary divergence of an epithelial linings-specific Shh enhancer2013
- Author(s)
  Tomoko Sagai1, Takanori Amano, Akiteru MKimura, Kiyoshi aeno, Tetsuaki Naruse
- Organizer
  第46回日本発生生物学会大会（APDBN共催）
- Place of Presentation
  松江
- Data Source
  KAKENHI-PROJECT-24247002
[Presentation] A BAC-transgenic mouse model for the long-range enhancer-promoter in teraction at the Shh locus2011
- Author(s)
  天野孝紀
- Organizer
  日本発生生物学会第44回大会
- Place of Presentation
  沖縄
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-22770224
[Presentation] A BAC-transgenic mouse model for the long range enhancer-promoter interaction at the Shh locus2011
- Author(s)
  天野孝紀, 他
- Organizer
  日本発生生物学会第44回大会
- Place of Presentation
  沖縄
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-22770224
[Presentation] Long-rangeエンハンサーによるShh遺伝子の発現制御2011
- Author(s)
  天野孝紀
- Organizer
  みんなで建設的に考える会
- Place of Presentation
  名古屋
- Year and Date
  2011-08-05
- Data Source
  KAKENHI-PROJECT-22770224
[Presentation] Regulatory elements for limb-specific expression of developmental genes in the coelacanth
- Author(s)
  天野孝紀、城石俊彦
- Organizer
  日本進化学会第16回大会
- Place of Presentation
  大阪 (高槻現代劇場)
- Year and Date
  2014-08-21 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-24247002
[Presentation] Mouse Hammer toe (Hm) mutation affects a long-range Shh regulation
- Author(s)
  Kousuke MourI, Tomoko Sagai, Takanori Amano, Toshihiko Shiroishi
- Organizer
  第47回日本発生生物学会大会
- Place of Presentation
  名古屋（ウインク愛知）
- Year and Date
  2014-05-27 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-24247002
[Presentation] Elimination of an oral epithelia-specific Shh enhancer causes an extra premolar-like tooth in mouse
- Author(s)
  Tomoko Sagai, Takanori Amano, Akiteru Maeno, Yoichi Mizushina, Toshihiko Shiroishi
- Organizer
  第47回日本発生生物学会大会
- Place of Presentation
  名古屋（ウインク愛知）
- Year and Date
  2014-05-27 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-24247002
[Presentation] Enhancer sharing and promoter insulation from enhancer activities: spatial and temporal organization of gene regulation around the mouse Shh locus
- Author(s)
  Takanori Amano, Tomoko Sagai, Toshihiko Shiroishi
- Organizer
  第47回日本発生生物学会大会
- Place of Presentation
  名古屋（ウインク愛知）
- Year and Date
  2014-05-27 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-24247002

1. SHIROISHI Toshihio (90171058)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
2. TAKADA Toyoyuki (20356257)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. KISO Ayako (80425834)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 吉田圭介 (80587452)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 越後貫成美 (40373287)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SAGAI Tomoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. MOURI kousuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 横山仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Amano Takanori 天野 孝紀

天野 孝紀 アマノ タカノリ

AMANO Takanori 天野 孝紀

Research Projects

Research Products

Co-Researchers

Adaptation to space environment and transgenerational effects explored using mitochondrial dysfunction model mice

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

マウス亜種間発現差を利用したシス多型の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Modeling complex diseases using mouse subspecies strainsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Enhancer-sharing and insulation via chromosomal dynamicsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cis-regulatory polymorphism responsible for allele-expression-bias that contributes to mouse phenotype

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Transcriptional regulation of Shh via chromosomal dynamics

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Screening of factors binding to the Shh limb enhancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 先端の分析法 第2版2022

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] 生物の科学 遺伝 2014年5月号2014

Author(s)

Total Pages

Publisher

Data Source

[Book] 生物機能モデルと新しいリソース・リサーチツール2011

Author(s)

Publisher

Data Source

[Book] 生物機能モデルと新しいリソース・リサーチツール 第I部 生物機能モデルの作製と利用 第1章 発生・形態形成 第5節 中胚葉性器官形成 第4項 四肢2011

Author(s)

Publisher

Data Source

[Journal Article] Inter-subspecies mouse F1 hybrid embryonic stem cell lines newly established for studies of allelic imbalance in gene expression2024

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] The shh limb enhancer is activated in patterned limb regeneration but not in hypomorphic limb regeneration in Xenopus laevis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gene regulatory landscape of the sonic hedgehog locus in embryonic development2020

Amano Takanori 天野孝紀

天野孝紀アマノタカノリ

AMANO Takanori 天野孝紀

[Book] 先端の分析法第2版2022

[Book] 生物の科学遺伝 2014年5月号2014

[Book] 生物機能モデルと新しいリソース・リサーチツール第I部生物機能モデルの作製と利用第1章発生・形態形成第5節中胚葉性器官形成第4項四肢2011

[Presentation] マウスEdnrb遺伝子座のトランスポゾン挿入変異による白斑発症メカニズム2021