Motegi Sei-ichiro 茂木精一郎

… Alternative Names

Researcher Number	20420185
Other IDs
Affiliation (Current)	2022: 群馬大学, 大学院医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2020 – 2021: 群馬大学, 大学院医学系研究科, 教授 2017 – 2019: 群馬大学, 大学院医学系研究科, 准教授 2016: 群馬大学, 大学院医学系研究科, 講師 2012 – 2015: 群馬大学, 医学(系)研究科(研究院), 講師 2013: 群馬大学, 大学院医学系研究科, 講師 2008: 群馬大, 生体調節研究所, 研究員 2007: Gunma University, 生体調節研究所, 研究員
Review Section/Research Field	Principal Investigator Dermatology / Basic Section 53050:Dermatology-related Except Principal Investigator Dermatology / Medical pharmacy / Collagenous pathology/Allergology / Basic Section 52010:General internal medicine-related / Basic Section 53050:Dermatology-related
Keywords	Principal Investigator 間葉系幹細胞 / 悪性黒色腫 / 創傷治癒 / SHPS-1 / CD47 / 樹状細胞 / ランゲルハンス細胞 / T細胞 / 接触皮膚炎 / 細胞間相互作用 … More Except Principal Investigator 線維化 / 全身性強皮症 / 強皮症 / 間葉系幹細胞 / 治療 / 膠原病 / 皮膚硬化 / 腎性全身性線維症 / ガドリニウム / 石灰化 / 腎性全身線維症 / 細胞内シグナル / アペリン / APJアゴニスト / MM07 / 細胞外ATP / ATP / アトピー性皮膚炎 / NK細胞 / 老化 / 早老症 / ラミンA / ウエルナー症候群 / Werner症候群 / ラミンＡ / エクソソーム / MFG-E8 Less

皮膚炎症性疾患における温度感受性TRPチャネルの役割と治療への応用Principal Investigator
- Principal Investigator
  
  茂木精一郎
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Gunma University
Treatment for skin sclerosis in systemic sclerosis by MSCs-derived exosome
- Principal Investigator
  
  横山洋子
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Gunma University
Elucidation of the pathogenesis of skin sclerosis and lipoatrophy in progeria and development of novel treatment
- Principal Investigator
  
  Endo Yukie
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Gunma University
Elucidation of the pathogenesis of acute-phase pressure ulcers and development of novel therapies: Focusing on mesenchymal stem cell-derived exosomesPrincipal Investigator
- Principal Investigator
  
  Motegi Sei-ichiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Gunma University
Development of new treatment in systemic sclerosis by regulating of apelin/APJ signaling
- Principal Investigator
  
  Yokoyama Yoko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Gunma University
The role of extracellular ATP in the pathogenesis of skin sclerosis and vasculopathy in systemic sclerosis
- Principal Investigator
  
  Ishikawa Osamu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Gunma University
Development of a new treatment for atopic dermatitis by activating NK cells
- Principal Investigator
  
  Kishi Chikako
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Gunma University
Elucidation of the regulation by secreted protein MFG-E8, and the development of new therapyPrincipal Investigator
- Principal Investigator
  
  Motegi Sei-ichiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Gunma University
The regulation of fibrosis and calcification by gadolinium
- Principal Investigator
  
  YAMADA Kazuya
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Gunma University
Role of mesenchymal stem cells in tumor angiogenesisPrincipal Investigator
- Principal Investigator
  
  MOTEGI Sei-ichiro
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Gunma University
新しい細胞間シグナル系による皮膚免疫機能の制御Principal Investigator
- Principal Investigator
  
  茂木精一郎
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Gunma University

All 2019 2018 2017 2016 2015 2013 Other

All Journal Article Presentation

[Journal Article] The Regulation of Skin Fibrosis in Systemic Sclerosis by Extracellular ATP via P2Y2 Purinergic Receptor.2019
- Author(s)
  Perera LMB, Sekiguchi A, Uchiyama A, Uehara A, Fujiwara C, Yamazaki S, Yokoyama Y, Ogino S, Torii R, Hosoi M, Ishikawa O, Motegi S
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: 139 Pages: 890-899
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10205
[Journal Article] Inhibitory Regulation of Skin Fibrosis in Systemic Sclerosis by Apelin/APJ Signaling.2018
- Author(s)
  Yokoyama Y, Sekiguchi A, Fujiwara C, Uchiyama A, Uehara A, Ogino S, Torii R, Ishikawa O, Motegi S
- Journal Title
  
  Arthritis & Rheumatology
  
  Volume: 70 Pages: 1661-72
- DOI
  10.1002/art.40533
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09968
[Journal Article] MFG-E8 drives melanoma growth by stimulating mesenchymal stromal cell-induced angiogenesis and M2 polarization of tumor-associated macrophages2016
- Author(s)
  Yamada K, Uchiyama A, Uehara A, Perera B, Ogino S, Yokoyama Y, Takeuchi Y, Udey MC, Ishikawa O, and Motegi S
- Journal Title
  
  Cancer Research
  
  Volume: 76 Pages: 4283-92
- DOI
  10.1158/0008-5472.can-15-2812
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461654
[Journal Article] Protective Effect of MFG-E8 after Cutaneous Ischemia-Reperfusion Injury.2015
- Author(s)
  Akihiko Uchiyama, Kazuya Yamada, Buddhini Perera, Sachiko Ogino, Yoko Yokoyama, Yuko Takeuchi, Osamu Ishikawa, and Sei-ichiro Motegi
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: 135 Pages: 1157-65
- DOI
  10.1038/jid.2014.515
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461654
[Presentation] Mechanistic insight into the extracellular ATP-induced IL-6 via purinergic receptor in systemic sclerosis dermal fibroblasts2017
- Author(s)
  Buddhini Perera, Akihiko Uchiyama, Akiko Sekiguchi, Chisako Fujwara, Osamu Ishikawa, Sei-ichiro Motegi
- Organizer
  2017 Society for Investigative Dermatology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10205
[Presentation] The regulation of skin fibrosis in systemic sclerosis by extracellular ATP via P2Y2 purinergic receptor2017
- Author(s)
  Buddhini Perera, Akiko Sekiguchi, Akihiko Uchiyama, Akihito Uehara, Chisako Fujwara, Sahori Yamazaki, Osamu Ishikawa, Sei-ichiro Motegi
- Organizer
  The 42nd annual meeting of the Japanese Society for Investigative Dermatology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10205
[Presentation] Inhibitory regulation of skin fibrosis in systemic sclerosis by apelin/APJ signaling2017
- Author(s)
  Yoko Yokoyama, Akiko Sekiguchi, Chisako Fujiwara, Akihiko Uchiyama, Sahori Yamazaki, Sachiko Ogino, Ryoko Torii, Osamu Ishikawa, and Sei-ichiro Motegi
- Organizer
  The 42nd annual meeting of the Japanese Society for Investigative Dermatology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09968
[Presentation] Inhibitory regulation of MFGE-8 on fibrosis in systemic sclerosis.2016
- Author(s)
  Fujiwara C, Uehara A, Yokoyama Y, Ogino S, Uchiyama A, sekiguchi A, Ogino S, Ishikawa O, Motegi S.
- Organizer
  The 41th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  Sendai
- Year and Date
  2016-12-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461654
[Presentation] MFG-E8 promotes mesenchymal stem cells-induced angiogenesis2015
- Author(s)
  Kazuya Yamada, Akihiko Uchiyama, Sachiko Ogino, Buddhini Perera, Yoko Yokoyama, Yuko Takeuchi, Osamu Ishikawa, and Sei-ichiro Motegi
- Organizer
  The 45th Annual ESDR Meeting
- Place of Presentation
  Rotterdam
- Year and Date
  2015-09-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461654
[Presentation] 腫瘍血管新生における間葉系幹細胞の役割2013
- Author(s)
  茂木精一郎
- Organizer
  日本皮膚科学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24791135
[Presentation] 間葉系幹細胞による悪性黒色腫の腫瘍血管新生の制御2013
- Author(s)
  山田和哉, 内山明彦, 上原顕仁, 荻野幸子, 横山洋子, 竹内裕子, Mark C. Udey, 石川治, 茂木精一郎
- Organizer
  第20回新群筑皮膚合同研究会
- Place of Presentation
  前橋
- Year and Date
  2013-10-18
- Data Source
  KAKENHI-PROJECT-24791135
[Presentation] 腫瘍血管新生における間葉系幹細胞の役割2013
- Author(s)
  茂木　精一郎、山田　和哉、内山　明彦、上原　顕仁、石川　治
- Organizer
  第112回日本皮膚科学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24791135
[Presentation] 間葉系幹細胞による悪性黒色腫の腫瘍血管新生の制御2013
- Author(s)
  山田和哉, 内山明彦, 上原顕仁, 荻野幸子, 横山洋子, 竹内裕子, 石川治, 茂木精一郎
- Organizer
  第60回北関東医学会総会
- Place of Presentation
  前橋
- Year and Date
  2013-09-26
- Data Source
  KAKENHI-PROJECT-24791135
[Presentation] Role of endothelin-1/endothelin receptor signaling in fibrosis and calcification in nephrogenic systemic fibrosis2013
- Author(s)
  Motegi S, Okada E, Uchiyama A, Yamada K, Uehara A, Ogino S, Takeuchi Y, Ishikawa O
- Organizer
  International Investiagtive Dermatology
- Place of Presentation
  Edinburgh
- Data Source
  KAKENHI-PROJECT-24790146
[Presentation] MFG-E8 promotes mesenchymal stem cells-induced angiogenesis in malignant melanoma
- Author(s)
  Kazuya Yamada, Akihiko Uchiyama, Buddhini Perera, Sachiko Ogino, Yoko Yokoyama, Yuko Takeuchi, Osamu Ishikawa, and Sei-ichiro Motegi
- Organizer
  39th Japanese Society for Investigative Dermatology
- Place of Presentation
  ホテル阪急エキスポパーク（大阪府吹田市）
- Year and Date
  2014-12-12 – 2014-12-14
- Data Source
  KAKENHI-PROJECT-26461654
[Presentation] Protective effect of MFG-E8 after cutaneous ischemia-reperfusion injury
- Author(s)
  Akihiko Uchiyama, Kazuya Yamada, Buddhini Perera, Sachiko Ogino, Yoko Yokoyama, Yuko Takeuchi, Osamu Ishikawa, and Sei-ichiro Motegi
- Organizer
  39th Japanese Society for Investigative Dermatology
- Place of Presentation
  ホテル阪急エキスポパーク（大阪府吹田市）
- Year and Date
  2014-12-12 – 2014-12-14
- Data Source
  KAKENHI-PROJECT-26461654

1. Yokoyama Yoko (00241901)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. YAMADA Kazuya (90420190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. Ishikawa Osamu (90168188)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. Kishi Chikako (60402707)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Endo Yukie (00372350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 天野博雄 (70302487)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Motegi Sei-ichiro 茂木 精一郎

MOTEGI Sei-ichiro 茂木 精一郎

茂木 精一郎 モテギ セイイチロウ

Research Projects

Research Products

Co-Researchers

皮膚炎症性疾患における温度感受性TRPチャネルの役割と治療への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Treatment for skin sclerosis in systemic sclerosis by MSCs-derived exosome

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the pathogenesis of skin sclerosis and lipoatrophy in progeria and development of novel treatment

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the pathogenesis of acute-phase pressure ulcers and development of novel therapies: Focusing on mesenchymal stem cell-derived exosomesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of new treatment in systemic sclerosis by regulating of apelin/APJ signaling

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of extracellular ATP in the pathogenesis of skin sclerosis and vasculopathy in systemic sclerosis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a new treatment for atopic dermatitis by activating NK cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the regulation by secreted protein MFG-E8, and the development of new therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The regulation of fibrosis and calcification by gadolinium

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of mesenchymal stem cells in tumor angiogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新しい細胞間シグナル系による皮膚免疫機能の制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The Regulation of Skin Fibrosis in Systemic Sclerosis by Extracellular ATP via P2Y2 Purinergic Receptor.2019

Author(s)

Journal Title

Data Source

[Journal Article] Inhibitory Regulation of Skin Fibrosis in Systemic Sclerosis by Apelin/APJ Signaling.2018

Author(s)

Journal Title

DOI

Motegi Sei-ichiro 茂木精一郎

MOTEGI Sei-ichiro 茂木精一郎

茂木精一郎モテギセイイチロウ