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Motegi Sei-ichiro  茂木 精一郎

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MOTEGI Sei-ichiro  茂木 精一郎

茂木 精一郎  モテギ セイイチロウ

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Researcher Number 20420185
Other IDs
Affiliation (Current) 2022: 群馬大学, 大学院医学系研究科, 教授
Affiliation (based on the past Project Information) *help 2020 – 2021: 群馬大学, 大学院医学系研究科, 教授
2017 – 2019: 群馬大学, 大学院医学系研究科, 准教授
2016: 群馬大学, 大学院医学系研究科, 講師
2012 – 2015: 群馬大学, 医学(系)研究科(研究院), 講師
2013: 群馬大学, 大学院医学系研究科, 講師
2008: 群馬大, 生体調節研究所, 研究員
2007: Gunma University, 生体調節研究所, 研究員
Review Section/Research Field
Principal Investigator
Dermatology / Basic Section 53050:Dermatology-related
Except Principal Investigator
Dermatology / Medical pharmacy / Collagenous pathology/Allergology / Basic Section 52010:General internal medicine-related / Basic Section 53050:Dermatology-related
Keywords
Principal Investigator
間葉系幹細胞 / 悪性黒色腫 / 創傷治癒 / SHPS-1 / CD47 / 樹状細胞 / ランゲルハンス細胞 / T細胞 / 接触皮膚炎 / 細胞間相互作用 … More / サイトカイン / 血管新生 / 強皮症 / 線維化 / 急性期褥瘡 / 酸化ストレス障害 / エクソソーム / 酸化ストレス / 褥瘡 / アトピー性皮膚炎 / 尋常性乾癬 / 温度感受性チャネル … More
Except Principal Investigator
線維化 / 全身性強皮症 / 強皮症 / 間葉系幹細胞 / 治療 / 膠原病 / 皮膚硬化 / 腎性全身性線維症 / ガドリニウム / 石灰化 / 腎性全身線維症 / 細胞内シグナル / アペリン / APJアゴニスト / MM07 / 細胞外ATP / ATP / アトピー性皮膚炎 / NK細胞 / 老化 / 早老症 / ラミンA / ウエルナー症候群 / Werner症候群 / ラミンA / エクソソーム / MFG-E8 Less
  • Research Projects

    (11 results)
  • Research Products

    (16 results)
  • Co-Researchers

    (6 People)
  •  皮膚炎症性疾患における温度感受性TRPチャネルの役割と治療への応用Principal Investigator

    • Principal Investigator
      茂木 精一郎
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      Gunma University
  •  Treatment for skin sclerosis in systemic sclerosis by MSCs-derived exosome

    • Principal Investigator
      横山 洋子
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      Gunma University
  •  Elucidation of the pathogenesis of skin sclerosis and lipoatrophy in progeria and development of novel treatment

    • Principal Investigator
      Endo Yukie
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Gunma University
  •  Elucidation of the pathogenesis of acute-phase pressure ulcers and development of novel therapies: Focusing on mesenchymal stem cell-derived exosomesPrincipal Investigator

    • Principal Investigator
      Motegi Sei-ichiro
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      Gunma University
  •  Development of new treatment in systemic sclerosis by regulating of apelin/APJ signaling

    • Principal Investigator
      Yokoyama Yoko
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Collagenous pathology/Allergology
    • Research Institution
      Gunma University
  •  The role of extracellular ATP in the pathogenesis of skin sclerosis and vasculopathy in systemic sclerosis

    • Principal Investigator
      Ishikawa Osamu
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Gunma University
  •  Development of a new treatment for atopic dermatitis by activating NK cells

    • Principal Investigator
      Kishi Chikako
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Gunma University
  •  Elucidation of the regulation by secreted protein MFG-E8, and the development of new therapyPrincipal Investigator

    • Principal Investigator
      Motegi Sei-ichiro
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Gunma University
  •  The regulation of fibrosis and calcification by gadolinium

    • Principal Investigator
      YAMADA Kazuya
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      Gunma University
  •  Role of mesenchymal stem cells in tumor angiogenesisPrincipal Investigator

    • Principal Investigator
      MOTEGI Sei-ichiro
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Dermatology
    • Research Institution
      Gunma University
  •  新しい細胞間シグナル系による皮膚免疫機能の制御Principal Investigator

    • Principal Investigator
      茂木 精一郎
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Dermatology
    • Research Institution
      Gunma University

All 2019 2018 2017 2016 2015 2013 Other

All Journal Article Presentation

  • [Journal Article] The Regulation of Skin Fibrosis in Systemic Sclerosis by Extracellular ATP via P2Y2 Purinergic Receptor.2019

    • Author(s)
      Perera LMB, Sekiguchi A, Uchiyama A, Uehara A, Fujiwara C, Yamazaki S, Yokoyama Y, Ogino S, Torii R, Hosoi M, Ishikawa O, Motegi S
    • Journal Title

      Journal of Investigative Dermatology

      Volume: 139 Pages: 890-899

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10205
  • [Journal Article] Inhibitory Regulation of Skin Fibrosis in Systemic Sclerosis by Apelin/APJ Signaling.2018

    • Author(s)
      Yokoyama Y, Sekiguchi A, Fujiwara C, Uchiyama A, Uehara A, Ogino S, Torii R, Ishikawa O, Motegi S
    • Journal Title

      Arthritis & Rheumatology

      Volume: 70 Pages: 1661-72

    • DOI

      10.1002/art.40533

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09968
  • [Journal Article] MFG-E8 drives melanoma growth by stimulating mesenchymal stromal cell-induced angiogenesis and M2 polarization of tumor-associated macrophages2016

    • Author(s)
      Yamada K, Uchiyama A, Uehara A, Perera B, Ogino S, Yokoyama Y, Takeuchi Y, Udey MC, Ishikawa O, and Motegi S
    • Journal Title

      Cancer Research

      Volume: 76 Pages: 4283-92

    • DOI

      10.1158/0008-5472.can-15-2812

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461654
  • [Journal Article] Protective Effect of MFG-E8 after Cutaneous Ischemia-Reperfusion Injury.2015

    • Author(s)
      Akihiko Uchiyama, Kazuya Yamada, Buddhini Perera, Sachiko Ogino, Yoko Yokoyama, Yuko Takeuchi, Osamu Ishikawa, and Sei-ichiro Motegi
    • Journal Title

      Journal of Investigative Dermatology

      Volume: 135 Pages: 1157-65

    • DOI

      10.1038/jid.2014.515

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461654
  • [Presentation] Mechanistic insight into the extracellular ATP-induced IL-6 via purinergic receptor in systemic sclerosis dermal fibroblasts2017

    • Author(s)
      Buddhini Perera, Akihiko Uchiyama, Akiko Sekiguchi, Chisako Fujwara, Osamu Ishikawa, Sei-ichiro Motegi
    • Organizer
      2017 Society for Investigative Dermatology Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10205
  • [Presentation] The regulation of skin fibrosis in systemic sclerosis by extracellular ATP via P2Y2 purinergic receptor2017

    • Author(s)
      Buddhini Perera, Akiko Sekiguchi, Akihiko Uchiyama, Akihito Uehara, Chisako Fujwara, Sahori Yamazaki, Osamu Ishikawa, Sei-ichiro Motegi
    • Organizer
      The 42nd annual meeting of the Japanese Society for Investigative Dermatology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10205
  • [Presentation] Inhibitory regulation of skin fibrosis in systemic sclerosis by apelin/APJ signaling2017

    • Author(s)
      Yoko Yokoyama, Akiko Sekiguchi, Chisako Fujiwara, Akihiko Uchiyama, Sahori Yamazaki, Sachiko Ogino, Ryoko Torii, Osamu Ishikawa, and Sei-ichiro Motegi
    • Organizer
      The 42nd annual meeting of the Japanese Society for Investigative Dermatology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09968
  • [Presentation] Inhibitory regulation of MFGE-8 on fibrosis in systemic sclerosis.2016

    • Author(s)
      Fujiwara C, Uehara A, Yokoyama Y, Ogino S, Uchiyama A, sekiguchi A, Ogino S, Ishikawa O, Motegi S.
    • Organizer
      The 41th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      Sendai
    • Year and Date
      2016-12-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461654
  • [Presentation] MFG-E8 promotes mesenchymal stem cells-induced angiogenesis2015

    • Author(s)
      Kazuya Yamada, Akihiko Uchiyama, Sachiko Ogino, Buddhini Perera, Yoko Yokoyama, Yuko Takeuchi, Osamu Ishikawa, and Sei-ichiro Motegi
    • Organizer
      The 45th Annual ESDR Meeting
    • Place of Presentation
      Rotterdam
    • Year and Date
      2015-09-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461654
  • [Presentation] 腫瘍血管新生における間葉系幹細胞の役割2013

    • Author(s)
      茂木精一郎
    • Organizer
      日本皮膚科学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24791135
  • [Presentation] 間葉系幹細胞による悪性黒色腫の腫瘍血管新生の制御2013

    • Author(s)
      山田和哉, 内山明彦, 上原顕仁, 荻野幸子, 横山洋子, 竹内裕子, Mark C. Udey, 石川 治, 茂木精一郎
    • Organizer
      第20回新群筑皮膚合同研究会
    • Place of Presentation
      前橋
    • Year and Date
      2013-10-18
    • Data Source
      KAKENHI-PROJECT-24791135
  • [Presentation] 腫瘍血管新生における間葉系幹細胞の役割2013

    • Author(s)
      茂木 精一郎、山田 和哉、内山 明彦、上原 顕仁、石川 治
    • Organizer
      第112回日本皮膚科学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24791135
  • [Presentation] 間葉系幹細胞による悪性黒色腫の腫瘍血管新生の制御2013

    • Author(s)
      山田和哉, 内山明彦, 上原顕仁, 荻野幸子, 横山洋子, 竹内裕子, 石川 治, 茂木精一郎
    • Organizer
      第60回北関東医学会総会
    • Place of Presentation
      前橋
    • Year and Date
      2013-09-26
    • Data Source
      KAKENHI-PROJECT-24791135
  • [Presentation] Role of endothelin-1/endothelin receptor signaling in fibrosis and calcification in nephrogenic systemic fibrosis2013

    • Author(s)
      Motegi S, Okada E, Uchiyama A, Yamada K, Uehara A, Ogino S, Takeuchi Y, Ishikawa O
    • Organizer
      International Investiagtive Dermatology
    • Place of Presentation
      Edinburgh
    • Data Source
      KAKENHI-PROJECT-24790146
  • [Presentation] MFG-E8 promotes mesenchymal stem cells-induced angiogenesis in malignant melanoma

    • Author(s)
      Kazuya Yamada, Akihiko Uchiyama, Buddhini Perera, Sachiko Ogino, Yoko Yokoyama, Yuko Takeuchi, Osamu Ishikawa, and Sei-ichiro Motegi
    • Organizer
      39th Japanese Society for Investigative Dermatology
    • Place of Presentation
      ホテル阪急エキスポパーク(大阪府吹田市)
    • Year and Date
      2014-12-12 – 2014-12-14
    • Data Source
      KAKENHI-PROJECT-26461654
  • [Presentation] Protective effect of MFG-E8 after cutaneous ischemia-reperfusion injury

    • Author(s)
      Akihiko Uchiyama, Kazuya Yamada, Buddhini Perera, Sachiko Ogino, Yoko Yokoyama, Yuko Takeuchi, Osamu Ishikawa, and Sei-ichiro Motegi
    • Organizer
      39th Japanese Society for Investigative Dermatology
    • Place of Presentation
      ホテル阪急エキスポパーク(大阪府吹田市)
    • Year and Date
      2014-12-12 – 2014-12-14
    • Data Source
      KAKENHI-PROJECT-26461654
  • 1.  Yokoyama Yoko (00241901)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 2.  YAMADA Kazuya (90420190)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  Ishikawa Osamu (90168188)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 4.  Kishi Chikako (60402707)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  Endo Yukie (00372350)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  天野 博雄 (70302487)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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