MUROYAMA Yuko 室山優子

Researcher Number	20422248
Affiliation (based on the past Project Information) *help	2017: 千葉大学, 大学院医学研究院, 特任講師 2013 – 2016: 千葉大学, 医学(系)研究科(研究院), 特任講師 2014 – 2015: 千葉大学, 大学院医学研究院, 特任講師 2012: 千葉大学, 医学(系)研究科(研究院), 講師 2012: 千葉大学, 大学院・医学研究院, 講師 … More 2011: 千葉大学, 医学(系)研究科(研究院), 特任講師 2008 – 2011: Chiba University, 大学院・医学研究院, 特任講師 2007: Chiba University, 大学院・医学研究院, 助教 2006: 千葉大学, 大学院医学研究院, 助手 Less
Review Section/Research Field	Principal Investigator Developmental biology Except Principal Investigator General anatomy (including histology/embryology) / Nerve anatomy/Neuropathology / Neuroscience in general / Neuroscience in general
Keywords	Principal Investigator 発生・分化 / 神経幹細胞 / 脳・神経 / 大脳皮質 / 幹細胞 / 神経細胞 / Notch / 電気穿孔法 / 神経前駆細胞 / Digital Differential Display … More / 哺乳類 / 遺伝子 / 神経科学 / Notchシグナル / in vivo electroporation / マウス / 応答能 … More Except Principal Investigator 発生・分化 / 細胞・組織 / 遺伝子 / 電気穿孔法 / 脳・神経 / 神経科学 / テトラサイクリン / 神経細胞 / 脊髄 / 神経幹細胞 / 発現制御 / ゲノム / ホメオボックス / 小脳 / 細胞神経科学 / 分子 Less

Mechanisms to control the number and size of the nucleolus
- Principal Investigator
  
  Saito Tetsuichiro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Chiba University
大脳新皮質における放射状グリアの形成機構Principal Investigator
- Principal Investigator
  
  室山優子
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Developmental biology
- Research Institution
  Chiba University
Molecular mechanisms to control morphologies of postmitotic neurons
- Principal Investigator
  
  SAITO Tetsuichiro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Chiba University
Spatiotemporal control mechanisms of neural circuit formation
- Principal Investigator
  
  SAITO Tetsuichiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  Chiba University
Functional analysis of Nepro, a novel Notch downstream gene requiredfor the maintenance of neocortex neural progenitor cellsPrincipal Investigator
- Principal Investigator
  
  MUROYAMA Yuko
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Developmental biology
- Research Institution
  Chiba University
Mechanisms to form neural circuits of the spinal cord and cerebellum
- Principal Investigator
  
  SAITO Tetsuichiro
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neuroscience in general
- Research Institution
  Chiba University
Analysis of molecular mechanisms regulating neural progenitor cells in the early neocortexPrincipal Investigator
- Principal Investigator
  
  MUROYAMA Yuko
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Developmental biology
- Research Institution
  Chiba University
大脳皮質の発生過程における神経幹細胞の応答能Principal Investigator
- Principal Investigator
  
  室山優子
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Developmental biology
- Research Institution
  Chiba University

All 2017 2016 2015 2014 2013 2012 2011 2010 2009 2007 Other

All Journal Article Presentation

[Journal Article] Olfactory Sensory Neurons Control Dendritic Complexity of Mitral Cells via Notch Signaling.2016
- Author(s)
  Yuko Muroyama, Atsushi Baba, Motoo Kitagawa, Tetsuichiro Saito
- Journal Title
  
  PLOS Genetics
  
  Volume: 12(12) Issue: 12 Pages: e1006514-e1006514
- DOI
  10.1371/journal.pgen.1006514
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K07072, KAKENHI-PROJECT-26460269, KAKENHI-PROJECT-16K08577, KAKENHI-PROJECT-16K15166
[Journal Article] Distorted coarse axon targeting and reduced dendrite connectivity underlie dysosmia after olfactory axon2016
- Author(s)
  Murai A, Iwata R, Fujimoto S, Aihara S, Tsuboi A, Muroyama Y, Saito T, Nishizaki K and Imai T
- Journal Title
  
  eNeuro
  
  Volume: 3 Issue: 5 Pages: 1-13
- DOI
  10.1523/eneuro.0242-16.2016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01446, KAKENHI-PROJECT-16H04664, KAKENHI-PROJECT-15J08987, KAKENHI-PROJECT-15K18353, KAKENHI-PROJECT-15K14327, KAKENHI-PROJECT-15K14335, KAKENHI-PROJECT-16K14568, KAKENHI-PROJECT-16K15166
[Journal Article] Control of gene expression in neurons by the use of in vivo electroporation and the tetracycline system2015
- Author(s)
  Tatsuya Sato, Yuko Muroyama, Tetsuichiro Saito
- Journal Title
  
  Neuromethods
  
  Volume: 102 Pages: 187-195
- DOI
  10.1007/978-1-4939-2459-2_15
- ISBN
  9781493924585, 9781493924592
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24300116, KAKENHI-PUBLICLY-25123701, KAKENHI-PROJECT-26640026
[Journal Article] Nepro is localized in the nucleolus and essential for preimplantation development in mice.2015
- Author(s)
  Masakazu Hashimoto, Tatsuya Sato, Yuko Muroyama, Lisa Fujimura, Masahiko Hatano, Tetsuichiro Saito
- Journal Title
  
  Development, Growth & Differentiation
  
  Volume: 57 Issue: 7 Pages: 529-538
- DOI
  10.1111/dgd.12232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07072, KAKENHI-PROJECT-26430033, KAKENHI-PUBLICLY-15H01149, KAKENHI-PROJECT-25460380, KAKENHI-PROJECT-25460942, KAKENHI-PROJECT-26640026
[Journal Article] Control of gene expression in neurons by the use of in vivo electroporation and the tetracycline system2014
- Author(s)
  Tatsuya Sato, Yuko Muroyama, Tetsuichiro Saito
- Journal Title
  
  NeuroMethods
  
  Volume: 印刷中
- Data Source
  KAKENHI-PROJECT-24300116
[Journal Article] Inducible gene expression in postmitotic neurons by an in vivo electroporation-based tetracycline system2013
- Author(s)
  Sato, T., Muroyama, Y. and Saito, T
- Journal Title
  
  Journal of Neuroscience Methods
  
  Volume: 214 Issue: 2 Pages: 170-176
- DOI
  10.1016/j.jneumeth.2013.01.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700410, KAKENHI-PROJECT-23770242, KAKENHI-PROJECT-24300116, KAKENHI-PUBLICLY-23123501
[Journal Article] Expression of major guidance receptors is differentially regulated in spinal commissural neurons transfated by mammalian Barh genes2010
- Author(s)
  Daisuke Kawauchi, Yoko Muroyama Tatsuya Sato, Tetsuichiro Saito
- Journal Title
  
  Dev.Biol. 344
  
  Pages: 1026-1034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240029
[Journal Article] Expression of major guidance receptors is differentially regulated in spin al commissural neurons transfated by mammalian Barh genes2010
- Author(s)
  Daisuke Kawauchi, Yuko Muroyama, Tatsuya Sato and Tetsuichiro Saito
- Journal Title
  
  Dev. Biol
  
  Volume: 344 Issue: 2 Pages: 1026-1034
- DOI
  10.1016/j.ydbio.2010.06.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240029
[Journal Article] Identification of Nepro, a gene required for the maintenance of neocortex neural progenitor cells downstream of Notch2009
- Author(s)
  Yuko Muroyama, Tetsuichiro Saito
- Journal Title
  
  Development 136
  
  Pages: 3889-3893
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240029
[Journal Article] Identification of Nepro, a gene required for the maintenance of neocortex neural progenitor cells downstream of Notch2009
- Author(s)
  Yuko Muroyama
- Journal Title
  
  Development 136
  
  Pages: 3889-3893
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770173
[Journal Article] Identification of Nepro, a gene required for the maintenance of neocortex neural progenitor cells downstream of Notch2009
- Author(s)
  Yuko Muroyama
- Journal Title
  
  Development 136
  
  Pages: 3889-3893
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240029
[Journal Article] Identification of Nepro, a gene required for the maintenance of neocortex neural progenitor cells downstream of Notch2009
- Author(s)
  Yuko Muroyama Tetsuichiro Saito
- Journal Title
  
  Development
  
  Volume: 136 Issue: 23 Pages: 3889-3893
- DOI
  10.1242/dev.039180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240029
[Journal Article] Identification of Nepro, a gene required for the maintenance of neocortex neural progenitor cells downstream of Notch.2009
- Author(s)
  Yuko Muroyama, Tetsuichiro Saito
- Journal Title
  
  Development Vol.136
  
  Pages: 3889-3893
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770173
[Presentation] Formation of discrete olfactory circuits by spontaneous activity2017
- Author(s)
  Takeshi Imai、Satoshi Fujimoto、Marcus Leiwe、Yuko Muroyama、Tetsuichiro Saito
- Organizer
  Neuroscience2017
- Data Source
  KAKENHI-PROJECT-16K15166
[Presentation] Mouse homing behavior and dendritic complexity of mitral cells are controlled by Notch signaling2017
- Author(s)
  Atsushi Baba、Yuko Muroyama、Motoo Kitagawa、Tetsuichiro Saito
- Organizer
  Neuroscience2017
- Data Source
  KAKENHI-PROJECT-16K15166
[Presentation] Notch signaling controls dendritic complexity of mitral cells2016
- Author(s)
  Yuko Muroyama, Motoo Kitagawa, Tetsuichiro Saito
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-16K15166
[Presentation] Intrinsic Spontaneous Network Activity in the Neonatal Mouse Olfactory Bulb is Required for Dendrite Pruning of Mitral Cells2016
- Author(s)
  MN. Leiwe, S. Fujimoto, Y. Muroyama, R. Kobayakawa, K. Kobayakawa, T. Saito, T. Imai
- Organizer
  Annual Meeting of Society for Neuroscience 2016
- Place of Presentation
  Convention Center (San Diego, U.S.A)
- Year and Date
  2016-11-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15166
[Presentation] Function and regulation of Nepro are different between the early neocortex and preimplantation embryos2016
- Author(s)
  Yuko Muroyama, Tetsuichiro Saito
- Organizer
  International Symposium "Neocortical Organization III"
- Place of Presentation
  東京大学（東京都・文京区）
- Year and Date
  2016-02-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26640026
[Presentation] Developmentally-regulated spontaneous network activity governs dendrite pruning of mitral cells to establish discrete connectivity2016
- Author(s)
  Satoshi Fujimoto, Marcus N. Leiwe, Yuko Muroyama, Reiko Kobayakawa, Ko Kobayakawa, Tetsuichiro Saito, Takeshi Imai
- Organizer
  Cold Spring Harbor Laboratory 2016 Meeting "Axon Guidance, Synapse Formation and Regeneration"
- Place of Presentation
  Cold Spring Harbor Laboratory (Cold Spring Harbor, U.S.A.)
- Year and Date
  2016-09-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15166
[Presentation] Function and regulation of Nepro are different between the early neocortex and preimplantation embryos2016
- Author(s)
  Yuko Muroyama, Tetsuichiro Saito
- Organizer
  第3回国際シンポジウム　Neocortical organization 3
- Place of Presentation
  東京大学（東京都文京区）
- Year and Date
  2016-02-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07072
[Presentation] Notchシグナルは嗅球僧帽細胞の樹状突起の形態を制御する2016
- Author(s)
  室山優子、北川元生、斎藤哲一郎
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-15K07072
[Presentation] Spontaneous neuronal activity is required for dendrite pruning of olfactory mitral cells in early postnatal development2015
- Author(s)
  Satoshi Fujimoto, Yuko Muroyama, Tetsuichiro Saito, Takeshi Imai
- Organizer
  Society for Neuroscience's 45th annual meeting
- Place of Presentation
  McCormick Place (Chicago, USA)
- Year and Date
  2015-10-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26640026
[Presentation] Early Postnatal Spontaneous Activity Is Required for Dendrite Pruning of Olfactory Mitral Cells2015
- Author(s)
  Satoshi Fujimoto, Yuko Muroyama, Tetsuichiro Saito, Takeshi Imai
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場（兵庫県・神戸市）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-26640026
[Presentation] Spontaneous neuronal activity is required for dendrite pruning of olfactory mitral cells in early postnatal development2015
- Author(s)
  Satoshi Fujimoto, Yuko Muroyama, Tetsuichiro Saito, Takeshi Imai
- Organizer
  The 13th International Symposium on Molecular and Neural Mechanisms of Taste and Olfactory Perception
- Place of Presentation
  九州大学（福岡県・福岡市）
- Year and Date
  2015-11-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26640026
[Presentation] Postmitotic dorsal spinal cord neurons are transfated into commissural neurons by induced misexpression of Barh12014
- Author(s)
  Tatsuya Sato, Yuko Muroyama, Tetsuichiro Saito
- Organizer
  北米神経科学会2014年会
- Place of Presentation
  Washington, DC, U.S.A.
- Year and Date
  2014-11-18
- Data Source
  KAKENHI-PROJECT-26640026
[Presentation] Postmitotic dorsal spinal cord neurons are transfated into commissural neurons by induced misexpression of Barh12014
- Author(s)
  Tatsuya Sato, Yuko Muroyama, Tetsuichiro Saito
- Organizer
  北米神経科学会2014年会
- Place of Presentation
  Washington, DC, U.S.A.
- Year and Date
  2014-11-18
- Data Source
  KAKENHI-PROJECT-24300116
[Presentation] Nepro is required for the maintenance of neural progenitor cells in the early neocortex2012
- Author(s)
  Yuko Muroyama, Tatsuya Sato and Tetsuichiro Saito
- Organizer
  1st International Symposium "Neocortical Organization"
- Place of Presentation
  岡崎
- Data Source
  KAKENHI-PROJECT-23770242
[Presentation] Functional analysis of Nepro, a gene required for the maintenance of neocortex neural progenitor cells2011
- Author(s)
  Tatsuya Sato, Yuko Muroyama and Tetsuichiro Saito
- Organizer
  第34回日本神経科学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23770242
[Presentation] 大脳皮質神経前駆細胞の維持に必要な遺伝子Neproの機能解析2011
- Author(s)
  佐藤達也, 室山優子, 斎藤哲一郎
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-20240029
[Presentation] 大脳皮質神経前駆細胞の維持におけるNotch下流因子Neproの機能2009
- Author(s)
  室山優子, 斎藤哲一郎
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-20240029
[Presentation] Nepro is involved in the maintenance of neocortex neural progenitor cells downstream of Notch2009
- Author(s)
  室山優子
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-20770173
[Presentation] Nepro is involved in the maintenance of neocortex neural progenitor cells downstream of Notch.2009
- Author(s)
  室山優子
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-20770173
[Presentation] マウス脊髄における部域特異的な細胞分化制御2009
- Author(s)
  室山優子
- Organizer
  第5回Chiba Neuroresearch Meeting
- Place of Presentation
  千葉
- Year and Date
  2009-05-30
- Data Source
  KAKENHI-PROJECT-20240029
[Presentation] 哺乳類大脳皮質の神経幹細胞で時期待異的に発現する遺伝子の解析2007
- Author(s)
  室山優子
- Organizer
  第30回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-18770195
[Presentation] Gene induction to postmitotic neurons by the use of in vivo electroporation and the tetracycline system
- Author(s)
  Tatsuya Sato, Yuko Muroyama, Tetsuichiro Saito
- Organizer
  Neurogenesis 2013 in Matsushima
- Place of Presentation
  ホテル松島大観荘（松島）
- Data Source
  KAKENHI-PROJECT-24300116
[Presentation] Tightly controlled induction of gene expression is achieved in postmitotic neurons by the combination of the tetracycline system and in vivo electroporation
- Author(s)
  Tatsuya Sato, Yuko Muroyama, Tetsuichiro Saito
- Organizer
  Neuro2013サテライトシンポジウム"Molecular & Cellular Mechanisms of Brain Development & Evolution"
- Place of Presentation
  京都府立医科大学（京都）
- Data Source
  KAKENHI-PROJECT-24300116
[Presentation] テトラサイクリン遺伝子発現誘導システムと電気穿孔法を組み合わせることにより分化した神経細胞において遺伝子発現を誘導できる
- Author(s)
  佐藤達也、室山優子、斎藤哲一郎
- Organizer
  第36回分子生物学会年会
- Place of Presentation
  神戸国際会議場（神戸）
- Data Source
  KAKENHI-PROJECT-24300116

1. SAITO Tetsuichiro (00202078)

# of Collaborated Projects: 4 results

# of Collaborated Products: 22 results
2. KAWAUCHI Daisuke (10400996)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. SATO Tatsuya (00568222)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
4. BABA Atsushi (70405215)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 坪井昭夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MUROYAMA Yuko 室山 優子

Research Projects

Research Products

Co-Researchers

Mechanisms to control the number and size of the nucleolus

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

大脳新皮質における放射状グリアの形成機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanisms to control morphologies of postmitotic neurons

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Spatiotemporal control mechanisms of neural circuit formation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of Nepro, a novel Notch downstream gene requiredfor the maintenance of neocortex neural progenitor cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms to form neural circuits of the spinal cord and cerebellum

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of molecular mechanisms regulating neural progenitor cells in the early neocortexPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

大脳皮質の発生過程における神経幹細胞の応答能Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Olfactory Sensory Neurons Control Dendritic Complexity of Mitral Cells via Notch Signaling.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Distorted coarse axon targeting and reduced dendrite connectivity underlie dysosmia after olfactory axon2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Control of gene expression in neurons by the use of in vivo electroporation and the tetracycline system2015

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] Nepro is localized in the nucleolus and essential for preimplantation development in mice.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Control of gene expression in neurons by the use of in vivo electroporation and the tetracycline system2014

Author(s)

Journal Title

Data Source

[Journal Article] Inducible gene expression in postmitotic neurons by an in vivo electroporation-based tetracycline system2013

Author(s)

Journal Title

MUROYAMA Yuko 室山優子