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iga-murahashi mutsunori  村橋 睦了 (伊賀 睦了)

… Alternative Names

伊賀 睦了

村橋 睦了  ムラハシ ムツノリ(イガムツノリ)

伊賀睦了

Murahashi Mutsunori  村橋 睦了

MUTSUNORI Iga  伊賀 睦了

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Researcher Number 20422420
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-0996-2199
Affiliation (Current) 2025: 東京慈恵会医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2025: 東京慈恵会医科大学, 医学部, 教授
2022 – 2023: 東京慈恵会医科大学, 医学部, 教授
2019 – 2020: 東京慈恵会医科大学, 医学部, 准教授
2017 – 2018: 九州大学, 大学病院, 助教
2008 – 2009: Kyushu University, 大学病院, 助教
Review Section/Research Field
Principal Investigator
Gastroenterology / Basic Section 55030:Cardiovascular surgery-related / Basic Section 53010:Gastroenterology-related
Except Principal Investigator
Basic Section 55020:Digestive surgery-related / Basic Section 53010:Gastroenterology-related / Basic Section 55010:General surgery and pediatric surgery-related
Keywords
Principal Investigator
線維化 / 免疫治療 / 膵癌 / リポソーム / 免疫チェックポイント阻害薬 / T細胞 / 線維化抑制ペプチド / オルガノイド / がん免疫治療 / 免疫療法 … More / スフェロイド / ELISPOTアッセイ / IFNγ産生 / CD8+T細胞 / シクロフォスファミド / 臨床試験 / 制御性T細胞 / 腫瘍抗原ペプチドワクチン / 腫瘍免疫 / 膵臓学 / 胆道学 … More
Except Principal Investigator
樹状細胞ワクチン / がん指向性リポソーム / 食道癌 / ネオ抗原ペプチド / 胃癌 / リポソーム / 腫瘍溶解性ウイルス / ELIspotアッセイ / 癌免疫細胞療法 / 膵臓癌 / neoantigen / 腫瘍免疫微小環境 / 膵癌 / WT1 / 免疫療法 / 腫瘍溶解ウィルス / ワクチン / 多機能リボソーム Less
  • Research Projects

    (11 results)
  • Research Products

    (24 results)
  • Co-Researchers

    (24 People)
  •  miRNA誘導リンパ管内皮細胞と間葉系幹細胞による二次性リンパ浮腫治療の研究開発Principal Investigator

    • Principal Investigator
      村橋 睦了 (伊賀 睦了)
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Jikei University School of Medicine
  •  進行・再発胃がんに対するがん指向性リポソームを利用した腫瘍溶解ウイルス療法の開発

    • Principal Investigator
      原 圭吾
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Jikei University School of Medicine
  •  ネオ抗原ペプチドを用いた胃癌に対する革新的個別化ワクチンの開発

    • Principal Investigator
      藤崎 宗春
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Jikei University School of Medicine
  •  腫瘍溶解ウイルス併用免疫療法による進行再発食道癌に対する革新的治療の開発

    • Principal Investigator
      谷島 雄一郎
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Jikei University School of Medicine
  •  がん指向性リポソームによる遺伝子制御を利用した膵癌腫瘍溶解性ウイルス療法の開発

    • Principal Investigator
      百田 禎郎
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Jikei University School of Medicine
  •  Development of pancreatic cancer treatment using fibrosis-inhibiting peptide and anticancer drug-encapsulating liposomePrincipal Investigator

    • Principal Investigator
      村橋 睦了 (伊賀睦了)
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Jikei University School of Medicine
  •  進行胃癌に対する多機能リポソームを用いた新規治療の開発

    • Principal Investigator
      宇野 耕平
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Jikei University School of Medicine
  •  進行膵癌における腫瘍免疫微小環境の再構築を目指した複合的免疫化学療法の開発

    • Principal Investigator
      小井戸 薫雄
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Jikei University School of Medicine
  •  進行・再発食道がんに対する革新的個別化樹状細胞ワクチン療法の開発

    • Principal Investigator
      高橋 慶太
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Jikei University School of Medicine
  •  Development of adoptive cell transfer using pancreatic cancer-specific genetically modified T cells combined with a desmoplasia-blocking peptide in pancreatic cancerPrincipal Investigator

    • Principal Investigator
      Murahashi Mutsunori
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Jikei University School of Medicine
      Kyushu University
  •  Development of an immune therapy against advanced solid tumors using the epitope peptides derived from novel tumor-associated antigensPrincipal Investigator

    • Principal Investigator
      MUTSUNORI Iga
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyushu University

All 2023 2021 2019 2018 2017 2009 2008

All Journal Article Presentation

  • [Journal Article] Clinical Trial of a Cancer Vaccine Targeting VEGF and KIF20A in Advanced Biliary Tract Cancer.2021

    • Author(s)
      Murahashi M, Tsuruta T, Yamada K, Hijikata Y, Ogata H, Kishimoto J, Yoshimura S, Hikichi T, Nakanishi Y, Tani K.
    • Journal Title

      Anticancer Res.

      Volume: 41 Issue: 3 Pages: 1485-1496

    • DOI

      10.21873/anticanres.14907

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09464
  • [Journal Article] Patched 1-interacting Peptide Represses Fibrosis in Pancreatic Cancer to Augment the Effectiveness of Immunotherapy.2019

    • Author(s)
      Oyama Y, Onishi H, Koga S, Murahashi M, Ichimiya S, Nakayama K, Fujimura A, Kawamoto M, Imaizumi A, Umebayashi M, Ohuchida K, Morisaki T, Nakamura M
    • Journal Title

      J immunother

      Volume: In press Issue: 4 Pages: 121-133

    • DOI

      10.1097/cji.0000000000000305

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09047, KAKENHI-PROJECT-19K09124, KAKENHI-PROJECT-19K22662, KAKENHI-PROJECT-17K09464, KAKENHI-PROJECT-18K08620, KAKENHI-PROJECT-18K08682, KAKENHI-PROJECT-18K08788
  • [Journal Article] Identification of Tumoricidal TCRs from Tumor-Infiltrating Lymphocytes by Single-Cell Analysis2018

    • Author(s)
      Shitaoka Kiyomi、Hamana Hiroshi、Kishi Hiroyuki、Hayakawa Yoshihiro、Kobayashi Eiji、Sukegawa Kenta、Piao Xiuhong、Lyu Fulian、Nagata Takuya、Sugiyama Daisuke、Nishikawa Hiroyoshi、Tanemura Atsushi、Katayama Ichiro、Murahashi Mutsunori、Takamatsu Yasushi、Tani Kenzaburo、Ozawa Tatsuhiko、Muraguchi Atsushi
    • Journal Title

      Cancer Immunology Research

      Volume: 6 Issue: 4 Pages: 378-388

    • DOI

      10.1158/2326-6066.cir-17-0489

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-16H06499, KAKENHI-PROJECT-15H04308, KAKENHI-PROJECT-15K09522, KAKENHI-PROJECT-18K19441, KAKENHI-PROJECT-17H01547, KAKENHI-PROJECT-15H04980, KAKENHI-PROJECT-17H04219, KAKENHI-PROJECT-17H06162, KAKENHI-PROJECT-17K09464
  • [Journal Article] A novel combination therapy for human oxaliplatin-resistant colorectal cancer using oxaliplatin and coxsackievirus A11.2018

    • Author(s)
      Wang, B., Ogata, H., Takishima, Y., Miyamoto, S., Inoue, H., Kuroda, M., Yamada, K., Hijikata, Y., Murahashi, M., Shimizu, H., Okazaki, T., Nakanishi, Y., Tani, K.
    • Journal Title

      Anticancer Res.

      Volume: 38 Issue: 11 Pages: 6121-6126

    • DOI

      10.21873/anticanres.12963

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01547, KAKENHI-PROJECT-16H05200, KAKENHI-PROJECT-16K19181, KAKENHI-PROJECT-17K09464
  • [Journal Article] RBPJ and MAML3: Potential therapeutic targets for small cell lung cancer.2018

    • Author(s)
      Onishi H, Ichimiya S, Yanai K, Umebayashi M, Nakamura K, Yamasaki A, Imaizumi A, Nagai S, Murahashi M, Ogata H, Morisaki T
    • Journal Title

      Anticancer Research

      Volume: 38(5) Issue: 8 Pages: 4543-4547

    • DOI

      10.21873/anticanres.12758

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10792, KAKENHI-PROJECT-18K08620, KAKENHI-PROJECT-18K08788, KAKENHI-PROJECT-17H04283, KAKENHI-PROJECT-16K10603, KAKENHI-PROJECT-17K09464
  • [Presentation] Combination therapy of immunostimulatory CVB3 and PD-L1 blockade works to enhance anti-cancer efficacy.2023

    • Author(s)
      Shohei Miyamoto, Miyako Sagara, Shun Ito, Yasushi Soda, Tetsu Akiyama, Mutsunori Murahashi, Kenzaburo Tani.
    • Organizer
      第29回日本遺伝子細胞治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-23K07383
  • [Presentation] 胃癌に対するコクサッキーウイルスB群3型を用いたウイルス療法の開発.2023

    • Author(s)
      坂下裕紀、宮本将平、小林由紀子、相良京、伊藤駿、谷憲三朗、村橋睦了.
    • Organizer
      第1回日本ウイルス療法学会学術集会
    • Data Source
      KAKENHI-PROJECT-23K07383
  • [Presentation] Combination therapy of immunostimulatory oncolytic coxsackievirus B3 and PD-L1 blockade works synergistically to enhance anti-cancer efficacy.2023

    • Author(s)
      Shohei Miyamoto, Miyako Sagara, Shun Ito, Akira Sakamoto, Yasushi Soda, Tetsu Akiyama, Mutsunori Murahashi, Kenzaburo Tani.
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K07383
  • [Presentation] 免疫刺激性遺伝子改変コクサッキーウイルス療法の開発.2023

    • Author(s)
      宮本将平、相良京、伊藤駿、坂下裕紀、小林由紀子、秋山徹、谷憲三朗、村橋睦了.
    • Organizer
      第1回日本ウイルス療法学会学術集会
    • Data Source
      KAKENHI-PROJECT-23K07383
  • [Presentation] Patched 1-interacting peptide represses fibrosis in pancreatic cancer to augment the effectiveness of immunotherapy2021

    • Author(s)
      村橋 睦了, 大山 康博, 大西 秀哉 , 草森 浩輔, 西川 元也, 古賀 智子, 一宮 脩, 中山 和典 , 藤村 晶子, 川元 真, 今泉 晃, 梅林 雅代, 大内田 研宙 , 森崎 隆, 中村 雅史
    • Organizer
      第18回日本臨床腫瘍学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K09464
  • [Presentation] Ptch1結合ペプチドによる膵癌免疫治療奏効率向上の可能性.2019

    • Author(s)
      大山康博, 大西秀哉, 一宮脩, 中山和典, 藤村晶子, 川元真, 山崎章生, 村橋睦了、中村雅史.
    • Organizer
      第119回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-17K09464
  • [Presentation] Coxsackievirus A11 as a novel oncolytic viral therapy for human colorectal cancer2019

    • Author(s)
      Hisanobu Ogata, Beibei Wang, Shoei Miyamoto, Yuto Takishima, Miyako Sagara, Mutsunori Murahashi, Hideya Onishi, Kenzaburo Tani.
    • Organizer
      AACR (American Association for Cancer Research) Annual Meeting 2019
    • Data Source
      KAKENHI-PROJECT-17K09464
  • [Presentation] がんワクチンOCV-C01による標準療法不応進行再発胆道がんに対する医師主導治験2019

    • Author(s)
      村橋睦了, 鶴田敏久, 山田一成, 土方康基, 緒方久修, 岸本淳司, 船越公太, 戸高浩司, 中西洋一, 谷憲三朗
    • Organizer
      第16回日本免疫治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K09464
  • [Presentation] Possibility for augmentation of responses by anti-PD-1 antibody against pancreatic cancer using Ptch1-binding peptide.2019

    • Author(s)
      村橋 睦了, 大山 康博, 大西 秀哉, 一宮 脩, 中山 和典, 藤村 晶子, 川元 真, 山崎 章生, 中村 雅史.
    • Organizer
      第11回日本血液疾患免疫療法学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K09464
  • [Presentation] Ptch1結合ペプチドによる膵癌免疫治療奏効率向上の可能性2018

    • Author(s)
      大山康博, 大西秀哉, 一宮脩, 中山和典, 藤村晶子, 川元真, 山崎章生, 村橋睦了, 中村雅史
    • Organizer
      第31回日本バイオセラピィ学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K09464
  • [Presentation] Hedgehog シグナル阻害による膵癌免疫治療奏効率向上の可能性2018

    • Author(s)
      大山康博, 大西秀哉, 一宮脩, 中山和典, 藤村晶子, 川元真, 山崎章生, 村橋睦了, 中村雅史
    • Organizer
      第118回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-17K09464
  • [Presentation] Investigator initiated clinical trial of cancer vaccine OCV-C01 in advanced and recurrent biliary tract cancer2018

    • Author(s)
      村橋睦了, 鶴田敏久, 山田一成, 土方康基, 緒方久修, 岸本淳司, 船越公太, 戸高浩司, 中西洋一, 谷憲三朗
    • Organizer
      第16回日本臨床腫瘍学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K09464
  • [Presentation] Characterization of tumor-infiltrating CD8+ T lymphocytes in diffuse large B cell lymphoma2018

    • Author(s)
      Mutsunori Murahashi, Hiroshi Hamana, Hiroyuki Kishi, Kotoe Katayama, Rui Yamaguchi, Satoru Miyano, Hisanobu Ogata, Hideya Onishi, Yasushi Takamatsu, Yoichi Nakanishi.
    • Organizer
      Keystone Symposia Conference, C5: Cancer Immunotherapy: Combinations
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09464
  • [Presentation] 活性化リンパ球のrandom migration能は癌免疫療法の効果予測因子となりうる2017

    • Author(s)
      川元 真、大西 秀哉、山崎 章生、森崎 隆、村橋 睦了、緒方 久修、中村 雅史
    • Organizer
      第23回国際個別化医療学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K09464
  • [Presentation] びまん性大細胞型B細胞リンパ腫における腫瘍浸潤CD8+Tリンパ球の解析2017

    • Author(s)
      村橋 睦了、浜名 洋、岸 裕幸、山口類、宮野 悟、緒方 久修、岡崎 利彦、宮本 将平、谷 憲三朗、大西 秀哉、高松 泰、中西 洋一
    • Organizer
      第9回血液疾患免疫療法学会
    • Data Source
      KAKENHI-PROJECT-17K09464
  • [Presentation] New strategies of immune and cell therapy targeting malignancy2009

    • Author(s)
      伊賀睦了
    • Organizer
      第71回日本血液学会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-23
    • Data Source
      KAKENHI-PROJECT-20790498
  • [Presentation] 進行再発固形腫瘍に対するシクロフォスファミド併用新規腫瘍関連抗原由来ペプチドを用いた腫瘍特異的強化ワクチン療法2009

    • Author(s)
      伊賀睦了、土方康基、末廣陽子、岡崎利彦、村上佑介、田中芳浩、中村祐輔、吉田浩二、角田卓也、谷憲三朗
    • Organizer
      第106回日本内科学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20790498
  • [Presentation] 進行・再発固形腫瘍 (消化器がん・肺がん・子宮頚がん) に対するシクロフォスファミド併用新規腫瘍関連抗原由来エピトープペプチドカクテルを用いた腫瘍特異的強化ワクチン療法第1相臨床試験2008

    • Author(s)
      伊賀睦了
    • Organizer
      第21回日本バイオセラピィ学会学術集会総会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-29
    • Data Source
      KAKENHI-PROJECT-20790498
  • [Presentation] 進行再発固形腫瘍に対する抗腫瘍ワクチン療法第1相臨床試験2008

    • Author(s)
      谷憲三朗、伊賀睦了、土方康基、末廣陽子、岡崎利彦、村上佑介、田中芳浩、中村祐輔、吉田浩二、角田卓也
    • Organizer
      第21回日本日本バイオセラピィ学会学術集会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20790498
  • 1.  増田 隆洋 (40649092)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 2.  矢野 文章 (80318005)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  谷島 雄一郎 (80385335)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  宇野 耕平 (80899386)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  藤崎 宗春 (50597979)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 6.  高橋 慶太 (70795096)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 7.  宮本 将平 (20758536)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 4 results
  • 8.  百田 禎郎 (90820366)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 9.  坂下 裕紀 (80911586)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 10.  小林 毅大 (10899868)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  西川 勝則 (70246429)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  原 圭吾 (90974717)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  佐藤 和秀 (50974763)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  黒河内 喬範 (90846601)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  大西 秀哉 (30553276)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 16.  岸 裕幸 (60186210)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 17.  西川 元也 (40273437)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  草森 浩輔 (90707407)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  小井戸 薫雄 (70266617)
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  • 20.  秋元 俊亮 (60838241)
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  • 21.  NAKAMURA Katsuya
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  • 22.  森崎 隆
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  • 23.  谷 憲三朗
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  • 24.  中村 雅史
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