Sekita Yoichi 関田洋一

… Alternative Names

SEKITA YOICHI 関田洋一

関田洋一セキタヨウイチ

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Researcher Number	20431950
Other IDs	https://orcid.org/0000-0002-6230-8719
Affiliation (Current)	2024: 北里大学, 理学部, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 北里大学, 理学部, 准教授 2015 – 2017: 北里大学, 理学部, 准教授 2009: 医科歯科大, 難治疾患研究所 2008: Tokyo Medical and Dental University, 難治疾患研究所, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 43050:Genome biology-related / Basic Section 50010:Tumor biology-related / Genome biology / 基礎ゲノム科学 Except Principal Investigator Basic Section 50010:Tumor biology-related / Basic Section 52050:Embryonic medicine and pediatrics-related
Keywords	Principal Investigator エピジェネティクス / エピゲノム / ゲノムインプリンティング / DNAメチル化 / エピゲノム編集 / 代謝産物 / AKTシグナル / 脱分化 / state transition / がん幹細胞 … More / グリオブラストーマ / インプリンティング疾患 / クロマチンリモデリング因子 / 幹細胞 / CRISPR/Cas9 / enChIP / Rtl1 / Peg11 / upd(14)症候群 / 新生仔期致死 / レトロトランスポゾン … More Except Principal Investigator アクチン細胞骨格 / メカノトランスダクション / 膠芽腫 / グリオーマ / インプリンティング / DNAメチル化 / インプリンティング異常症 Less

Elucidation of the mechanism of tumor formation through mechanosensory defects
- Principal Investigator
  
  堤弘次
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kitasato University
Exploration and Analysis of Epigenome Control Core Using DNA Methylation Editing TechnologyPrincipal Investigator
- Principal Investigator
  
  関田洋一
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43050:Genome biology-related
- Research Institution
  Kitasato University
インプリンティング異常症エピ変異の病態およびDNAメチル化維持機構の解明
- Principal Investigator
  
  鏡雅代
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  National Center for Child Health and Development
がん幹細胞発生でのAktシグナル経路によるエピゲノム制御と代謝制御の解明Principal Investigator
- Principal Investigator
  
  関田洋一
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kitasato University
Comprehensive analysis of genome imprinting regulationPrincipal Investigator
- Principal Investigator
  
  SEKITA YOICHI
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Genome biology
- Research Institution
  Kitasato University
哺乳類特異的レトロトランスポゾン由来のタンパク質、Peg11/Rtl1の機能解析Principal Investigator
- Principal Investigator
  
  関田洋一
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  基礎ゲノム科学
- Research Institution
  Tokyo Medical and Dental University

All 2023 2022 2021 2020 2018 2017 2016 2015 2008

All Journal Article Presentation

[Journal Article] Mechanism of promotion of cell reprogramming by AKT signal2023
- Author(s)
  関田洋一、木村透
- Journal Title
  
  生化学
  
  Volume: 95 Issue: 1 Pages: 66-71
- DOI
  10.14952/SEIKAGAKU.2023.950066
- ISSN
  0037-1017
- Year and Date
  2023-02-25
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07577
[Journal Article] Epigenome editing reveals core DNA methylation for imprinting control in the Dlk1-Dio3 imprinted domain2022
- Author(s)
  Kojima Shin、Shiochi Naoya、Sato Kazuki、Yamaura Mamiko、Ito Toshiaki、Yamamura Nodoka、Goto Naoki、Odamoto Mika、Kobayashi Shin、Kimura Tohru、Sekita Yoichi
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 50 Issue: 9 Pages: 5080-5094
- DOI
  10.1093/nar/gkac344
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07577, KAKENHI-PROJECT-22K06046
[Journal Article] Switching defective/sucrose non‐fermenting chromatin remodeling complex coordinates meiotic gene activation via promoter remodeling and Meiosin activation in female germline2022
- Author(s)
  Ito Toshiaki、Ohta Masami、Osada Atsuki、Nishiyama Akira、Ishiguro Kei‐Ichiro、Tamura Tomohiko、Sekita Yoichi、Kimura Tohru
- Journal Title
  
  Genes to Cells
  
  Volume: 28 Issue: 1 Pages: 15-28
- DOI
  10.1111/gtc.12990
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07577, KAKENHI-PROJECT-22K06046
[Journal Article] Five multicopy gene family genes expressed during the maternal-to-zygotic transition are not essential for mouse development2021
- Author(s)
  Wakabayashi Mizuki、Tamura Shiori、Kanzaki Satoko、Kosugi Mayuko、Yoshimura Yuki、Ito Toshiaki、Nagata Kei、Sato Kazuha、Takada Shuji、Sekita Yoichi、Kimura Tohru
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 534 Pages: 752-757
- DOI
  10.1016/j.bbrc.2020.11.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07577
[Journal Article] A RUNX?CBFβ-driven enhancer directs the Irf8 dose-dependent lineage choice between DCs and monocytes2021
- Author(s)
  Murakami Koichi、Sasaki Haruka、Nishiyama Akira、Kurotaki Daisuke、Kawase Wataru、Ban Tatsuma、Nakabayashi Jun、Kanzaki Satoko、Sekita Yoichi、Nakajima Hideaki、Ozato Keiko、Kimura Tohru、Tamura Tomohiko
- Journal Title
  
  Nature Immunology
  
  Volume: 22 Issue: 3 Pages: 301-311
- DOI
  10.1038/s41590-021-00871-y
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07372, KAKENHI-PROJECT-20K07577, KAKENHI-PROJECT-16H06279
[Journal Article] AKT signaling is associated with epigenetic reprogramming via the upregulation of TET and its cofactor, alpha-ketoglutarate during iPSC generation2021
- Author(s)
  Sekita Y, Sugiura Y, Matsumoto A, Kawasaki Y, Akasaka K, Konno R, Shimizu M, Ito T, Sugiyama E, Yamazaki T, Kanai E, Nakamura T, Suematsu M, Ishino F, Kodera Y, Kohda T, Kimura T.
- Journal Title
  
  Stem Cell Res Ther.
  
  Volume: - Issue: 1 Pages: 510-510
- DOI
  10.1186/s13287-021-02578-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H05374, KAKENHI-PROJECT-19H00978, KAKENHI-PROJECT-20K07577, KAKENHI-PROJECT-20K20584
[Journal Article] SWI/SNF chromatin remodeling complex is required for initiation of sex-dependent differentiation in mouse germline2021
- Author(s)
  Ito Toshiaki、Osada Atsuki、Ohta Masami、Yokota Kana、Nishiyama Akira、Niikura Yuichi、Tamura Tomohiko、Sekita Yoichi、Kimura Tohru
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 24074-24074
- DOI
  10.1038/s41598-021-03538-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07577
[Journal Article] Involvement of Nlrp9a/b/c in mouse preimplantation development2020
- Author(s)
  Kanzaki Satoko, Tamura Shiori, Ito Toshiaki, Wakabayashi Mizuki, Saito Koji, Kato Shigeki, Ohta Yasutaka, Sekita Yoichi, Kimura Tohru
- Journal Title
  
  Reproduction
  
  Volume: 160 Issue: 2 Pages: 181-191
- DOI
  10.1530/rep-19-0516
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06227, KAKENHI-PROJECT-20K07577
[Journal Article] Reprogramming of germ cells into pluripotency2016
- Author(s)
  Sekita Y, Nakamura T, Kimura T
- Journal Title
  
  World J. Stem Cells
  
  Volume: 8 Issue: 8 Pages: 251-259
- DOI
  10.4252/wjsc.v8.i8.251
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-25112006, KAKENHI-PROJECT-15K18458, KAKENHI-ORGANIZER-25112001
[Journal Article] CRISPR/Cas9-mediated reporter knock-in in mouse haploid embryonic stem cells2015
- Author(s)
  Kimura, Y., Oda, M., Nakatani, T., Sekita, Y., Monfort, A., Wutz, A., Mochizuki, H., and Nakano, T
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 10710-10710
- DOI
  10.1038/srep10710
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18458, KAKENHI-PROJECT-15H02509
[Journal Article] Stella controls chromocenter formation through regulation of Daxx expression in 2-cell embryos.2015
- Author(s)
  Arakawa, T., Nakatani, T., Oda, M., Kimura, Y., Sekita, Y., Kimura, T., Nakamura, T., and Nakano, T.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 466 Issue: 1 Pages: 60-60
- DOI
  10.1016/j.bbrc.2015.08.106
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K18458, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112006, KAKENHI-PROJECT-26640063, KAKENHI-PROJECT-25291053, KAKENHI-PROJECT-15H02509
[Journal Article] Stella preserves maternal chromosome integrity by inhibiting 5hmC-dependent gammaH2AX accumulation.2015
- Author(s)
  Nakatani et al.
- Journal Title
  
  EMBO Reports
  
  Volume: 16 Issue: 5 Pages: 582-589
- DOI
  10.15252/embr.201439427
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390097, KAKENHI-PLANNED-25112006, KAKENHI-PUBLICLY-25125712, KAKENHI-PROJECT-25291053, KAKENHI-PROJECT-25712035, KAKENHI-PROJECT-26640063, KAKENHI-PROJECT-26660250, KAKENHI-PROJECT-15K18458, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-15H02509
[Journal Article] 染色体14番の父性2倍体症候群の治療を目指したmicroRNA投与法の開発2008
- Author(s)
  関田洋一、金児-石野知子、石野史敏
- Journal Title
  
  Chemical Biology 2
  
  Pages: 12-13
- Data Source
  KAKENHI-PROJECT-20710146
[Presentation] Epigenome editing reveals core DNA methylation for imprinting control in the Dlk1-Dio3 imprinted domain.2023
- Author(s)
  Yoichi Sekita, Shin Kojima, Naoya Shiochi, Tohru Kimura
- Organizer
  Genomic Imprinting, from Biology to Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07577
[Presentation] Epigenome editing reveals core DNA methylation for imprinting control in the Dlk1-Dio3 imprinted domain.2023
- Author(s)
  Yoichi Sekita, Shin Kojima, Naoya Shiochi, Tohru Kimura
- Organizer
  The 21st Takeda Science Foundation Symposium on Bioscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07577
[Presentation] 性染色体がコードするヒストン脱メチル化酵素KDM5CとKDM5Dのマウス胚発生における機能的差異と相同性2022
- Author(s)
  永田圭、小杉真由子、大谷舞衣、池田優美、吉川友里香、板倉陽子、豊田雅士、関田洋一、木村透
- Organizer
  第45回分子生物学会
- Data Source
  KAKENHI-PROJECT-20K07577
[Presentation] Nlrp5及びNlrp9の雌マウスの生殖能における役割2022
- Author(s)
  横田佳奈、田村史織、永田圭、神崎理子、関田洋一、木村透
- Organizer
  第45回分子生物学会
- Data Source
  KAKENHI-PROJECT-20K07577
[Presentation] エピゲノム編集によるDlk1-Dio3インプリントドメインでのDNAメチル化の機能解析2022
- Author(s)
  関田洋一、他３名
- Organizer
  第15回日本エピジェネティクス研究会年会
- Data Source
  KAKENHI-PROJECT-20K07577
[Presentation] STELLAによるZFP57の制御機構の解析2022
- Author(s)
  御園杏里、山﨑瑛司、中村肇伸、木村透、関田洋一
- Organizer
  第45回分子生物学会
- Data Source
  KAKENHI-PROJECT-20K07577
[Presentation] SWI/SNFクロマチンリモデリング複合体による生殖細胞の性分化開始機構2022
- Author(s)
  太田昌美、伊藤駿瑛、長田純輝、西山晃、石黒啓一郎、田村智彦、関田洋一、木村透
- Organizer
  第45回分子生物学会
- Data Source
  KAKENHI-PROJECT-20K07577
[Presentation] AKTシグナル経路による、iPS細胞作製過程での、代謝リモデリングを介したエピゲノム制御機構2022
- Author(s)
  関田洋一
- Organizer
  第19回北里疾患プロテオーム研究会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07577
[Presentation] エピゲノム編集によるDlk1-Dio3インプリントドメインでのDNAメチル化の機能解析2022
- Author(s)
  関田洋一、他３名
- Organizer
  第45回分子生物学会ワークショップ
- Data Source
  KAKENHI-PROJECT-20K07577
[Presentation] SWI/SNFクロマチンリモデリング複合体による始原生殖細胞の性分化制御機構2020
- Author(s)
  長田純輝、伊藤駿瑛、西山晃、田村智彦、関田洋一、木村透
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K07577
[Presentation] DNA脱メチル化ツールを用いたIG-DMRにおけるDNAメチル化の機能解析2020
- Author(s)
  児島進、塩地直弥、木村透、関田洋一
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K07577
[Presentation] AKT promotes somatic cell nuclear reprogramming through α-KG2018
- Author(s)
  関田洋一、松元愛香里、川崎佑季、杉浦悠毅、紺野亮、小寺義男、幸田尚、石野史敏、木村透
- Organizer
  第16回幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-15K18458
[Presentation] AKT promotes somatic cell nuclear reprogramming through α-KG2017
- Author(s)
  松元愛香里、関田洋一、川崎佑季、杉浦悠毅、小寺義男、幸田尚、石野史敏、木村透
- Organizer
  第15回幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-15K18458
[Presentation] Physiological roles of the genes expressed during maternal zygotic transition2017
- Author(s)
  神﨑理子、若林美月、高田修二、関田洋一、木村透
- Organizer
  第15回幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-15K18458
[Presentation] AKT promotes somatic cell nuclear reprogramming through α-KG2017
- Author(s)
  松元愛香里、関田洋一、川崎佑季、杉浦悠毅、小寺義男、幸田尚、石野史敏、木村透
- Organizer
  第15回幹細胞シンポジウム
- Place of Presentation
  東京大学（東京都文京区）
- Year and Date
  2017-05-26
- Data Source
  KAKENHI-PROJECT-15K18458
[Presentation] Essential roles of Snf5 in female germ cell sex differentiation2017
- Author(s)
  伊藤駿瑛、関田洋一、Charles Roberts、木村透
- Organizer
  第15回幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-15K18458
[Presentation] Identification and analysis of imprinting control region-binding proteins2017
- Author(s)
  関田洋一、吉村祐樹、藤井穂高、木村透
- Organizer
  第15回幹細胞シンポジウム
- Data Source
  KAKENHI-PROJECT-15K18458
[Presentation] enChIP法によるゲノムインプリンティング制御領域結合因子の網羅的探索2016
- Author(s)
  吉村祐樹、関田洋一、鏡雅代、紺野亮、藤井穂高、小寺義男、木村透
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K18458
[Presentation] AKTシグナルはαケトグルタル酸を介して体細胞核の初期化を促進する2016
- Author(s)
  松元愛香里、関田洋一、川崎佑季、杉浦悠毅、小寺義男、幸田尚、石野史敏、木村透
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K18458
[Presentation] 細胞の初期化過程でのシグナル伝達経路の役割2015
- Author(s)
  関田洋一、木村透
- Organizer
  2015年分子生物学会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-15K18458
[Presentation] レトロトランスポゾン由来の遺伝子Sirh-familyの解析2008
- Author(s)
  成瀬美衣、小野竜一、関田洋一、石井雅之、中村健司、日野敏昭、鈴木-右島理可、幸田尚、横山峯介、金児-石野知子、石野史敏
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-20710146
[Presentation] Contribution of Retrot ransposons to the Evolution of Genomic Imprinting and Placentation in Mammals2008
- Author(s)
  Ishino F, Ono R, Suzuki S, Sekita Y, Naruse M, Koda T and Kaneko-Ishino T.
- Organizer
  International Symposium on Decoding Epigenetic Code
- Place of Presentation
  Tokyo University, Tokyo
- Data Source
  KAKENHI-PROJECT-20710146
[Presentation] 哺乳類特異的なレトロトランスポゾンによる哺乳類の胎生進化2008
- Author(s)
  石野史敏、小野竜一、関田洋一、鈴木俊介、成瀬美衣、入江将仁、幸田尚、横山峯介、中村健司、金児-石野知子
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-20710146
[Presentation] 個体発生に重要な役割を果たすアンチセンスRNA : RNAi機構を介したアンチセンスRNAによるPeg11/Rtl1遺伝子の発現制御2008
- Author(s)
  金児-石野知子、関田洋一、遠藤大輔、鏡雅代、小野竜一、幸田尚、緒方勤、石野史敏
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-20710146
[Presentation] Evolution of placentation in eutherian mammals contributed by exaptation of PEG10 and PEG11/RTL1 from retrotransposons2008
- Author(s)
  Ishino F, Ono R, Suzuki S, Sekita Y, Naruse M, Koda T and Kaneko-Ishino T.
- Organizer
  8th NIBB-EMBL Joint Meeting "Evolution : Genomces, Cell Types and Shapes"
- Place of Presentation
  Okazaki Conference Center, Okazaki
- Data Source
  KAKENHI-PROJECT-20710146
[Presentation] Roles of Peg11/Rtl1 in neo- and postnatal growth2008
- Author(s)
  Sekita Y, Kagaini, M, Endo, D, Ono R, Kohda T, Ogata T, Kaneko-Ishino T and Ishino F.
- Organizer
  EMBO Workshop on Genomic Imprinting
- Place of Presentation
  TEMASEK LifeScience Laboratory, Singapore
- Data Source
  KAKENHI-PROJECT-20710146

1. 木村透 (50280962)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
2. 松本俊英 (10623184)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 鏡雅代 (70399484)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 堤弘次 (50569853)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 柴原一陽 (30791016)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SATO Koji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. NAKAMURA Toshinobu

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 太田安隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 西山晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sekita Yoichi 関田 洋一

SEKITA YOICHI 関田 洋一

関田 洋一 セキタ ヨウイチ

Research Projects

Research Products

Co-Researchers

Elucidation of the mechanism of tumor formation through mechanosensory defects

Principal Investigator

Project Period (FY)

Research Category

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Research Institution

Exploration and Analysis of Epigenome Control Core Using DNA Methylation Editing TechnologyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

インプリンティング異常症エピ変異の病態およびDNAメチル化維持機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

がん幹細胞発生でのAktシグナル経路によるエピゲノム制御と代謝制御の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

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Comprehensive analysis of genome imprinting regulationPrincipal Investigator

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哺乳類特異的レトロトランスポゾン由来のタンパク質、Peg11/Rtl1の機能解析Principal Investigator

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[Journal Article] Mechanism of promotion of cell reprogramming by AKT signal2023

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[Journal Article] Epigenome editing reveals core DNA methylation for imprinting control in the Dlk1-Dio3 imprinted domain2022

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[Journal Article] Switching defective/sucrose non‐fermenting chromatin remodeling complex coordinates meiotic gene activation via promoter remodeling and Meiosin activation in female germline2022

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[Journal Article] Five multicopy gene family genes expressed during the maternal-to-zygotic transition are not essential for mouse development2021

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[Journal Article] A RUNX?CBFβ-driven enhancer directs the Irf8 dose-dependent lineage choice between DCs and monocytes2021

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[Journal Article] AKT signaling is associated with epigenetic reprogramming via the upregulation of TET and its cofactor, alpha-ketoglutarate during iPSC generation2021

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[Journal Article] SWI/SNF chromatin remodeling complex is required for initiation of sex-dependent differentiation in mouse germline2021

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Sekita Yoichi 関田洋一

SEKITA YOICHI 関田洋一

関田洋一セキタヨウイチ