OKAWA Katsuya 大川克也

Researcher Number	20444458
Affiliation (based on the past Project Information) *help	2008: Kyoto University, 医学研究科, その他(グループリーダー) 2008: Kyoto University, 医学研究科, グループリーダー 2007: Kyoto University, 医学研究科, その他(グループルー)
Review Section/Research Field	Principal Investigator General medical chemistry
Keywords	Principal Investigator サブフェムトモル / 電気泳動 / 分析科学 / プロテオーム / 蛋白質 / 生体分子医学

Research Projects
(1 results)
Research Products
(20 results)

Identification of sub-femto mole protein from gel electrophoresisPrincipal Investigator
- Principal Investigator
  
  OKAWA Katsuya
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University

All 2009 2008 2007

All Journal Article

[Journal Article] mDia2 shuttles between the nucleus and the cytoplasm through the Importin-{alpha}/{beta}- and CRM1-mediated nuclear transport mechanism2009
- Author(s)
  Miki T, Okawa K, Sekimoto T, Yoneda Y, Watanabe S, Ishizaki T, Narumiya S
- Journal Title
  
  J Biol Chem 284(9)
  
  Pages: 5753-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590275
[Journal Article] Anti-moesin antibodies in the serum of patients with aplastic anemia stimulate peripheral blood mononuclear cells to secrete TNF-alpha and IFN-gamma2009
- Author(s)
  Takamatsu H, Espinoza JL, Lu X, Qi Z, Okawa K, Nakao S
- Journal Title
  
  J Immunol 182(1)
  
  Pages: 703-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590275
[Journal Article] RECK forms cowbell-shaped dimers and inhibits matrix metalloproteinase-catalyzed cleavage of fibronectin2009
- Author(s)
  Omura A, Matsuzaki T, Mio K, Ogura T, Yamamoto M, Fujita A, Okawa K, Kitayama H, Takahashi C, Sato C, Noda M
- Journal Title
  
  J Biol Chem 284(6)
  
  Pages: 3461-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590275
[Journal Article] Isolation and characterization of postsplicing lariat-intron complexes2009
- Author(s)
  Yoshimoto R, Kataoka N, Okawa K, Ohno M
- Journal Title
  
  Nucleic Acids Res 37(3)
  
  Pages: 891-902
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590275
[Journal Article] Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP2008
- Author(s)
  Hosokawa N, Wada I, Nagasawa K, Moriyama T, Okawa K, Nagata K
- Journal Title
  
  J Biol Chem 283(30)
  
  Pages: 20914-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590275
[Journal Article] IQGAP3 regulates cell proliferation through the Ras/ERK signalling cascade2008
- Author(s)
  Nojima H, Adachi M, Matsui T, Okawa K, Tsukita S, Tsukita S
- Journal Title
  
  Nat Cell Biol 10(8)
  
  Pages: 971-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590275
[Journal Article] CCAN makes multiple contacts with centromeric DNA to provide distinct pathways to the outer kinetochore2008
- Author(s)
  Hori T, Amano M, Suzuki A, Backer CB, Welburn JP, Dong Y, McEwen BF, Shang WH, Suzuki E, Okawa K, Cheeseman IM, Fukagawa T
- Journal Title
  
  Cell 135(6)
  
  Pages: 1039-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590275
[Journal Article] MKKS is a centrosome-shuttling protein degraded by disease-causing mutations via CHIP-mediated ubiquitination2008
- Author(s)
  Hirayama S, Yamazaki Y, Kitamura A, Oda Y, Morito D, Okawa K, Kimura H, Cyr DM, Kubota H, Nagata K.
- Journal Title
  
  Mol Biol Cell 19(3)
  
  Pages: 899-911
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590275
[Journal Article] Biochemical characterization of the Rho GTPase-regulated actin assembly by diaphanous-related formins, mDia1 and Daam1, in platelets2008
- Author(s)
  Higashi T, Ikeda T, Shirakawa R, Kondo H, Kawato M, Horiguchi M, Okuda T, Okawa K, Fukai S, Nureki O, Kita T, Horiuchi H
- Journal Title
  
  J Biol Chem 283(13)
  
  Pages: 8746-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590275
[Journal Article] Loss of Borealin/DasraB leads to defective cell proliferation, p53 accumulation and early embryonic lethality2008
- Author(s)
  Yamanaka Y, Heike T, Kumada T, ShibataM, Takaoka Y, Kitano A, Shiraishi K, Kato T, Nagato M, Okawa K, Furushima K, Nakao K, Nakamura Y, Taketo MM, Aizawa S, Nakahata T
- Journal Title
  
  Mech Dev 125(5-6)
  
  Pages: 441-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590275
[Journal Article] Optimized proteomic analysis on gels of cell-cell adhering junctional membrane proteins2008
- Author(s)
  Yamazaki Y, Okawa K, Yano T, Tsukita S, Tsukita S
- Journal Title
  
  Biochemistry 47(19)
  
  Pages: 5378-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590275
[Journal Article] Regulation of platelet dense granule secretion by the Ral GTPase-exocyst pathway2008
- Author(s)
  Kawato M, Shirakawa R, Kondo H, Higashi T, Ikeda T, Okawa K, Fukai S, Nureki O, Kita T, Horiuchi H
- Journal Title
  
  J Biol Chem 283(1)
  
  Pages: 166-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590275
[Journal Article] Heat-shock protein 105 interacts with and suppresses aggregation of mutant Cu/Zn superoxide dismutase : clues to a possible strategy for treating ALS2007
- Author(s)
  Yamashita H, Kawamata J, Okawa K, Kanki R, Nakamizo T, Hatayama T, Yamanaka K, Takahashi R, Shimohama S
- Journal Title
  
  J Neurochem 102(5)
  
  Pages: 1497-505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590275
[Journal Article] Control of immune responses by antigen-specific regulatory T cells expressing the folate receptor2007
- Author(s)
  Yamaguchi T, Hirota K, Nagahama K, Okawa K, Takahashi T, Nomura T, Sakaguchi S
- Journal Title
  
  Immunity 27(1)
  
  Pages: 145-59
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590275
[Journal Article] Gab family proteins are essential for postnatal maintenance of cardiac function via neuregulin-1/ErbB signaling2007
- Author(s)
  Nakaoka Y, Nishida K, Narimatsu M, Kamiya A, Minami T, Sawa H, Okawa K, Fujio Y, Koyama T, Maeda M, Sone M, Yamasaki S, Arai Y, Koh GY, Kodama T, Hirota H, Otsu K, Hirano T, Mochizuki N
- Journal Title
  
  J Clin Invest 117(7)
  
  Pages: 1771-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590275
[Journal Article] Factors associated with a purine-rich exonic splicing enhancer sequence in Xenopus oocyte nucleus2007
- Author(s)
  Masuyama K, Taniguchi I, Okawa K, OhnoM
- Journal Title
  
  Biochem Biophys Res Commun 359(3)
  
  Pages: 580-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590275
[Journal Article] Enhancement of alpha-secretase cleavage of amyloid precursor protein by a metalloendopeptidase nardilysin2007
- Author(s)
  Hiraoka Y, Ohno M, Yoshida K, Okawa K, Tomimoto H, Kita T, Nishi E
- Journal Title
  
  J Neurochem 102(5)
  
  Pages: 1595-605
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590275
[Journal Article] Cyclin-dependent kinaselike 5 is a novel target of immunotherapy in adult T-cell leukemia2007
- Author(s)
  Kawahara M, Hori T, Matsubara Y, Okawa K, Uchiyama T
- Journal Title
  
  J Immunother 30(5)
  
  Pages: 499-505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590275
[Journal Article] The reversion-inducing cysteine-rich protein with Kazal motifs(RECK)interacts with membrane type 1 matrix metalloproteinase and CD13/aminopeptidase N and modulates their endocytic pathways2007
- Author(s)
  Miki T, Takegami Y, Okawa K, Muraguchi T, Noda M, Takahashi C
- Journal Title
  
  J Biol Chem 282(16)
  
  Pages: 12341-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590275
[Journal Article] In vitro analyses of the production and activity of secondary small interfering RNAs in C. elegans2007
- Author(s)
  Aoki K, Moriguchi H, Yoshioka T, Okawa K, Tabara H.
- Journal Title
  
  EMBO J 26(24)
  
  Pages: 5007-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590275

OKAWA Katsuya 大川 克也

Research Projects

Research Products

Identification of sub-femto mole protein from gel electrophoresisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] mDia2 shuttles between the nucleus and the cytoplasm through the Importin-{alpha}/{beta}- and CRM1-mediated nuclear transport mechanism2009

Author(s)

Journal Title

Data Source

[Journal Article] Anti-moesin antibodies in the serum of patients with aplastic anemia stimulate peripheral blood mononuclear cells to secrete TNF-alpha and IFN-gamma2009

Author(s)

Journal Title

Data Source

[Journal Article] RECK forms cowbell-shaped dimers and inhibits matrix metalloproteinase-catalyzed cleavage of fibronectin2009

Author(s)

Journal Title

Data Source

[Journal Article] Isolation and characterization of postsplicing lariat-intron complexes2009

Author(s)

Journal Title

Data Source

[Journal Article] Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP2008

Author(s)

Journal Title

Data Source

[Journal Article] IQGAP3 regulates cell proliferation through the Ras/ERK signalling cascade2008

Author(s)

Journal Title

Data Source

[Journal Article] CCAN makes multiple contacts with centromeric DNA to provide distinct pathways to the outer kinetochore2008

Author(s)

Journal Title

Data Source

[Journal Article] MKKS is a centrosome-shuttling protein degraded by disease-causing mutations via CHIP-mediated ubiquitination2008

Author(s)

Journal Title

Data Source

[Journal Article] Biochemical characterization of the Rho GTPase-regulated actin assembly by diaphanous-related formins, mDia1 and Daam1, in platelets2008

Author(s)

Journal Title

Data Source

[Journal Article] Loss of Borealin/DasraB leads to defective cell proliferation, p53 accumulation and early embryonic lethality2008

Author(s)

Journal Title

Data Source

[Journal Article] Optimized proteomic analysis on gels of cell-cell adhering junctional membrane proteins2008

Author(s)

Journal Title

Data Source

[Journal Article] Regulation of platelet dense granule secretion by the Ral GTPase-exocyst pathway2008

Author(s)

Journal Title

Data Source

[Journal Article] Heat-shock protein 105 interacts with and suppresses aggregation of mutant Cu/Zn superoxide dismutase : clues to a possible strategy for treating ALS2007

Author(s)

Journal Title

Data Source

[Journal Article] Control of immune responses by antigen-specific regulatory T cells expressing the folate receptor2007

Author(s)

Journal Title

Data Source

[Journal Article] Gab family proteins are essential for postnatal maintenance of cardiac function via neuregulin-1/ErbB signaling2007

Author(s)

Journal Title

Data Source

[Journal Article] Factors associated with a purine-rich exonic splicing enhancer sequence in Xenopus oocyte nucleus2007

Author(s)

Journal Title

Data Source

[Journal Article] Enhancement of alpha-secretase cleavage of amyloid precursor protein by a metalloendopeptidase nardilysin2007

Author(s)

Journal Title

Data Source

[Journal Article] Cyclin-dependent kinaselike 5 is a novel target of immunotherapy in adult T-cell leukemia2007

Author(s)

Journal Title

OKAWA Katsuya 大川克也