IWAMOTO Takaaki 岩本顕聡

Researcher Number	20448773
Affiliation (based on the past Project Information) *help	2014: 奈良県立医科大学, 医学部, 研究助教 2013: 奈良県立医科大学, 医学部, 研究員 2008 – 2013: 奈良県立医科大学, 医学部, 博士研究員 2008: 奈良県立医大, 医学部, 研究員 2007: Nara Medical University, 医学部, 研究員
Review Section/Research Field	Principal Investigator Neurology / Human pathology Except Principal Investigator Risk sciences of radiation/Chemicals / Dermatology / Psychiatric science
Keywords	Principal Investigator 国際情報交換, アメリカ / 神経障害 / ヌクレオチド除去修復 / 色素性乾皮症 / 酸化的DNA損傷サイクロプリン / 癌診断 / 癌 / γ-tubulin / 蛍光免疫染色 / 中心体 … More Except Principal Investigator … More ヌクレオチド除去修復 / DNA付加体 / 有害化学物質 / 4-OHEN-DNA付加体 / 乳がん / エストロゲン補充療法 / 人体有害物質 / ピリミジン二量体 / 硫黄欠乏性毛髮発育異常症 / ピリミジンニ量体 / TFIIH / XPD / 紫外線 / 硫黄欠乏性毛髪発育異常症 / 色素性乾皮症 / 皮膚発がん / DNA修復 / DNA損傷 / 神経毒性 / アミロイドベータ重合体 Less

Possible contribution of oxidative DNA damage 8,5'-purine cyclodeoxynucleosides to progressive neurodegeneration of xeroderma pigmentosumPrincipal Investigator
- Principal Investigator
  
  IWAMOTO Takaaki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Nara Medical University
Induction and repair of 4-OHEN-DNA adducts in human breast cancer cells by the metabolites of equine estrogens
- Principal Investigator
  
  MORI Toshio
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Nara Medical University
How do mutations in the XPD result in different skin cancer susceptibilities in patients with xeroderma pigmentosum or trichothiodystrophy?
- Principal Investigator
  
  MORI Toshio
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Nara Medical University
Study about defense function against amyloid-beta toxicity to central nervous system cells: from the viewpoint of DNA repair
- Principal Investigator
  
  KISHIMOTO Toshifumi, MORIKAWA Masayuki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Nara Medical University
中心体異常を指標にした癌診断法の開発Principal Investigator
- Principal Investigator
  
  岩本顕聡
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Nara Medical University

All 2014 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Quantitative and in situ detection of oxidatively generated DNA damage 8,5’-cyclo-2’-deoxyadenosine using an immunoassay with a novel monoclonal antibody2014
- Author(s)
  T. Iwamoto, P.J. Brooks, T. Nishiwaki, K. Nishimura, N. Kobayashi, S. Sugiura and T. Mori.
- Journal Title
  
  Photochem. Photobiol.
  
  Volume: xx Issue: 4 Pages: 829-836
- DOI
  10.1111/php.12239
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23510081, KAKENHI-PROJECT-23591626, KAKENHI-PROJECT-24651052, KAKENHI-PROJECT-24790895, KAKENHI-PROJECT-26550042
[Journal Article] Tmem100, an ALK1 signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesis2012
- Author(s)
  S. Somekawa, K. Imagawa, H. Hayashi, M. Sakabe, T. Ioka, G .E. Sato, K. Inada, T. Iwamoto, T. Mori, S. Uemura, O. Nakagawa, and Y. Saito
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 109 Pages: 12064-12069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510081
[Journal Article] DNA損傷特異的モノクローナル抗体2012
- Author(s)
  森俊雄, 岩本顕聡
- Journal Title
  
  放射線生物研究
  
  Volume: 47 Pages: 112-125
- NAID
  40019392777
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510081
[Journal Article] DNA損傷特異的モノクローナル抗体2012
- Author(s)
  森俊雄、岩本顕聡
- Journal Title
  
  放射線生物研究
  
  Volume: 47 Pages: 112-125
- NAID
  40019392777
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790895
[Journal Article] Tmem100, an ALK1 signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesis.2012
- Author(s)
  染川智
- Journal Title
  
  Proc. Nat. Acad. Sci. USA
  
  Volume: 109 Issue: 30 Pages: 12064-12069
- DOI
  10.1073/pnas.1207210109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390274, KAKENHI-PROJECT-24790895
[Journal Article] DNA 損傷特異的モノクローナル抗体2011
- Author(s)
  森俊雄, 岩本顕聡
- Journal Title
  
  放射線生物研究
  
  Volume: 47 Pages: 112-125
- NAID
  40019392777
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510081
[Journal Article] Proteolytic fragmentation and sugar chains of plasma ADAMTS13 purified by a conformation- dependent monoclonal antibody.2010
- Author(s)
  H. Hiura, T. Matsui, M. Matsumoto, Y. Hori, A. Isonishi, S. Kato, T. Iwamoto, T. Mori, Y. Fujimura
- Journal Title
  
  J.Biochem 148
  
  Pages: 403-4011
- NAID
  10027878689
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591324
[Journal Article] Quantitative detection of 4-hydroxyequilenin-DNA adducts in mammalian cells using an immunoassay with a novel monoclonal antibody.2010
- Author(s)
  Y. Okahashi, T. Iwamoto, N. Suzuki, S. Shibutani, S. Sugiura, S. Itoh, T. Nishiwaki, S. Ueno, T. Mori.
- Journal Title
  
  Nucleic Acids Res 38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591324
[Journal Article] Protein kinase C gamma, a protein causative for dominant ataxia, negatively regulates nuclear import of recessive-ataxia-related aprataxin.2009
- Author(s)
  H. Asai, M. Hirano, K. Shimada, T. Kiriyama, Y. Furiya, M. Ikeda, T. Iwamoto, T. Mori, K. Nishinaka, N. Konishi, F. Udaka, S. Ueno
- Journal Title
  
  Hum Mol Genet 18
  
  Pages: 3533-3543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591324
[Journal Article] Effect of Prolyl-hydroxyproline (Pro-Hyp), a food-derived collagen peptide in human blood on growth of fibroblasts from mouse skin.2009
- Author(s)
  Y. Shigemura, K. Iwai, F. Morimatsu, T. Iwamoto, T. Mori, C. Oda, T. Taira, E. Y. Park, Y. Nakamura, K. Sato
- Journal Title
  
  J Agric Food Chem 57
  
  Pages: 444-449
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591324
[Journal Article] Comparative study of nucleotide excision repair defects between XPD-mutated fibroblasts derived from trichothiodystrophy and xeroderma pigmentosum patients2008
- Author(s)
  T. Nishiwaki, N. Kobayashi, T. Iwamoto, A. Yamamoto, S. Sugiura, Y.-C. Liu, A. Sarasin, Y. Okahashi, M. Hirano, S. Ueno, T. Mori
- Journal Title
  
  DNA Repair 7
  
  Pages: 1990-1998
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591324
[Journal Article] Comparative study of nucleotide excision repair defects between XPD-mutated fibroblasts derived from trichothiodystrophy and xeroderma pigmentosum patients2008
- Author(s)
  Nishiwaki T, Kobayashi N, Iwamoto T, Yamamoto A, Sugiura S, Liu YC, Sarasin A, Okahashi Y, Hirano M, Ueno S, Mori T
- Journal Title
  
  DNA repair 7
  
  Pages: 1990-1998
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591367
[Presentation] Quantitative and in situ detection of oxidatively generated DNA damage 8,5'-cyclo-2'-deoxyadenosine using an immunoassay with a novel monoclonal antibody2014
- Author(s)
  T. Iwamoto, P.J. Brooks, N. Kobayashi, S. Sugiura and T. Mori
- Organizer
  International symposium on xeroderma pigmentosum and related diseases : Disorders of DNA damage response -Bench to bedside-
- Place of Presentation
  Kobe
- Data Source
  KAKENHI-PROJECT-23510081
[Presentation] Quantitative and in situ detection of oxidatively generated DNA damage 8,5’-cyclo-2’-deoxyadenosine using an immunoassay with a novel monoclonal antibody2014
- Author(s)
  T. Iwamoto, P.J. Brooks, N. Kobayashi, S. Sugiura and T. Mori
- Organizer
  International symposium on xeroderma pigmentosum and related diseases: Disorders of DNA damage response -Bench to bedside-
- Place of Presentation
  Kobe
- Data Source
  KAKENHI-PROJECT-23510081
[Presentation] Quantitative and in situ detection of oxidatively generated DNA damage 8,5'-cyclo-2'-deoxyadenosine using an immunoassay with a novel monoclonal antibody2014
- Author(s)
  T. Iwamoto, P.J. Brooks, N. Kobayashi, S. Sugiura and T. Mori
- Organizer
  International symposiumon xeroderma pigmentosum and related diseases: Disorders of DNA damage response-Bench to bedside-
- Place of Presentation
  Kobe
- Data Source
  KAKENHI-PROJECT-24790895
[Presentation] 太陽紫外線による3主要ピリミジン2量体型 DNA 損傷の誘発2011
- Author(s)
  森俊雄、吉田唯真、西村和樹、岩本顕聡、池畑広伸、小林信彦
- Organizer
  第33回日本光医学・光生物学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23510081
[Presentation] 太陽紫外線による3主要ピリミジン2量体型DNA損傷の誘発2011
- Author(s)
  森　俊雄、吉田唯真、西村和樹、岩本顕聡、池畑広伸、小林信彦
- Organizer
  第33回日本光医学・光生物学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23510081
[Presentation] 太陽紫外線によるピリミジン2量体型 DNA 損傷の誘発2011
- Author(s)
  西村和樹、吉田唯真、岩本顕聡、池畑広伸、小林信彦、森俊雄
- Organizer
  日本放射線影響学会第54回大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23510081
[Presentation] Dewar型ピリミジン二量体は熱に不安定である2010
- Author(s)
  森俊雄、吉田淳一、岩本顕聡、池畑広伸、小林信彦
- Organizer
  第32回日本光医学・光生物学会
- Place of Presentation
  東京
- Year and Date
  2010-07-31
- Data Source
  KAKENHI-PROJECT-20591324
[Presentation] 紫外線誘発 Dewar型ピリミジン二量体を認識するモノクローナル抗体の樹立と応用2009
- Author(s)
  岩本顕聡、岡橋友美子、池畑広伸、小林信彦、森俊雄
- Organizer
  第31回日本光医学・光生物学会
- Place of Presentation
  大阪
- Year and Date
  2009-07-25
- Data Source
  KAKENHI-PROJECT-20591324
[Presentation] XPD変異を共通する二つの遺伝疾患で紫外線皮膚発がん頻度に大差が生じる機構の解析(1)2008
- Author(s)
  森俊雄、西脇知永、岩本顕聡、小林信彦、上野聡
- Organizer
  第30回日本光医学・光生物学会
- Place of Presentation
  松江
- Year and Date
  2008-07-11
- Data Source
  KAKENHI-PROJECT-20591324
[Presentation] Determination of 4-hydroxyequilenin-DNA adducts in tissues from mice treated with conjugated equine estrogens2008
- Author(s)
  Y.Okahashi, T.Iwamoto, S. Shibutani, S.Ueno, T.Mori
- Organizer
  American Association for Cancer Research
- Place of Presentation
  San Diego, USA
- Year and Date
  2008-04-14
- Data Source
  KAKENHI-PROJECT-20591324
[Presentation] High sensitive immunoassay for detection of abnormal centrosomes of cancer2007
- Author(s)
  稲田吉昭、岩本顕聡、森俊雄
- Organizer
  原子炉専門研究会
- Place of Presentation
  京都大学原子炉実験所
- Year and Date
  2007-09-28
- Data Source
  KAKENHI-PROJECT-19790266
[Presentation] 新規モノクローナル抗体を用いた酸化的DNA損傷サイクロプリンの定量測定と可視化
- Author(s)
  岩本顕聡、P.J. Brooks、小林信彦、杉浦重樹、森　俊雄
- Organizer
  第３６回日本光医学光生物学会
- Place of Presentation
  大阪
- Year and Date
  2014-07-25 – 2014-07-26
- Data Source
  KAKENHI-PROJECT-24790895
[Presentation] Quantitative and in situ detection of oxidatively generated DNA damage 8,5'-cyclo-2'-deoxyadenosine using an immunoassay with a novel monoclonal antibody
- Author(s)
  T. Iwamoto, P.J. Brooks, N. Kobayashi, S.Sugiura and T. Mori
- Organizer
  16th International Congress on Photobiology
- Place of Presentation
  Cordoba, Argentina
- Year and Date
  2014-09-08 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-24790895
[Presentation] 新規モノクローナル抗体を用いた酸化的DNA損傷サイクロプリンの定量測定と可視化
- Author(s)
  森　俊雄、岩本顕聡、小林信彦、杉浦重樹
- Organizer
  日本放射線影響学会第５７回大会
- Place of Presentation
  鹿児島
- Year and Date
  2014-10-01 – 2014-10-03
- Data Source
  KAKENHI-PROJECT-24790895

1. MORI Toshio (10115280)

# of Collaborated Projects: 3 results

# of Collaborated Products: 19 results
2. KISHIMOTO Toshifumi (60201456)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. MORIKAWA Masayuki (30305726)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. NAKANE Hironobu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. HAYASHI Masaharu

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. BROOKS P.J.

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

IWAMOTO Takaaki 岩本 顕聡

Research Projects

Research Products

Co-Researchers

Possible contribution of oxidative DNA damage 8,5'-purine cyclodeoxynucleosides to progressive neurodegeneration of xeroderma pigmentosumPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Induction and repair of 4-OHEN-DNA adducts in human breast cancer cells by the metabolites of equine estrogens

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

How do mutations in the XPD result in different skin cancer susceptibilities in patients with xeroderma pigmentosum or trichothiodystrophy?

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study about defense function against amyloid-beta toxicity to central nervous system cells: from the viewpoint of DNA repair

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

中心体異常を指標にした癌診断法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Quantitative and in situ detection of oxidatively generated DNA damage 8,5’-cyclo-2’-deoxyadenosine using an immunoassay with a novel monoclonal antibody2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tmem100, an ALK1 signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesis2012

Author(s)

Journal Title

Data Source

[Journal Article] DNA損傷特異的モノクローナル抗体2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] DNA損傷特異的モノクローナル抗体2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Tmem100, an ALK1 signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesis.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DNA 損傷特異的モノクローナル抗体2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Proteolytic fragmentation and sugar chains of plasma ADAMTS13 purified by a conformation- dependent monoclonal antibody.2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Quantitative detection of 4-hydroxyequilenin-DNA adducts in mammalian cells using an immunoassay with a novel monoclonal antibody.2010

Author(s)

Journal Title

Data Source

[Journal Article] Protein kinase C gamma, a protein causative for dominant ataxia, negatively regulates nuclear import of recessive-ataxia-related aprataxin.2009

Author(s)

Journal Title

Data Source

[Journal Article] Effect of Prolyl-hydroxyproline (Pro-Hyp), a food-derived collagen peptide in human blood on growth of fibroblasts from mouse skin.2009

Author(s)

Journal Title

Data Source

IWAMOTO Takaaki 岩本顕聡