Ueda Takumi 上田卓見

… Alternative Names

UEDA Takumi 上田卓見

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Researcher Number	20451859
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院薬学研究科, 教授
Affiliation (based on the past Project Information) *help	2024: 大阪大学, 大学院薬学研究科, 教授 2018 – 2024: 東京大学, 大学院薬学系研究科(薬学部), 准教授 2016 – 2018: 東京大学, 大学院薬学系研究科(薬学部), 助教 2011 – 2015: 東京大学, 薬学研究科(研究院), 助教 2013: 東京大学, 大学院薬学系研究科, 助教 … More 2011 – 2012: 東京大学, 大学院・薬学系研究科, 助教 2007 – 2009: The University of Tokyo, 大学院・薬学系研究科, 助教 2008: 東大, 薬学研究科(研究院), 助教 Less
Review Section/Research Field	Principal Investigator Physical pharmacy / Complex systems / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Biological Sciences / Medium-sized Section 47:Pharmaceutical sciences and related fields / Transformative Research Areas, Section (II) Except Principal Investigator Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related / Basic Section 47050:Environmental and natural pharmaceutical resources-related / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Biological Sciences / Complex systems
Keywords	Principal Investigator NMR / GPCR / 膜タンパク質 / 構造生物学 / 膜蛋白質 / 転移交差飽和法 / オピオイド受容体 / アドレナリン受容体 / システム生物学 / アレスチン … More / G蛋白質 / アデノシンA2A受容体 / 蛋白質-蛋白質相互作用 / 動的構造平衡 / 光合成明反応 / 膜透過性 / 環状ペプチド / 中分子 / 滞在時間 / Gタンパク質 / 数理モデル / 交換モンテカルロ法 / 脂質二重膜 / ナノディスク / DHA / スパースモデリング / 機械学習 / マルコフ連鎖モンテカルロ法 / ユビキチン / 蛋白質ー蛋白質相互作用 / 蛋白質-蛋白質複合体 / Tikhonov regularization / Co-ANAFOR / シグナル伝達 / 薬学 / 蛋白質 / Segmental labeling / Protein Trans-Splicing / 交差飽和法 / タンパク質―タンパク質相互作用 / 過渡的相互作用 / マルチドメイン蛋白質 / ニ成分制御系 / 過渡的複合体 / CCR1 / ケモカイン受容体 / 昆虫細胞発現系 / transferred cross saturation / electron transfer / protein-protein interaction / photosynthesis / Membrane protein / 電子移動反応 / タンパク質-タンパク質相互作用 / 光合成名反応 / 核磁気共鳴法 / 生化学 / 循環的電子伝達 / フェレドキシン / 光化学系I … More Except Principal Investigator 構造生物学 / 膜タンパク質 / 核磁気共鳴法 / 主鎖環化反応 / 核磁気共鳴 / タンパク質 / 生体共役反応 / 動的立体構造 / GPCR / 動的構造 / NMR / 動的構造平衡 / 多剤耐性トランスポーター / イオンチャネル / Gタンパク質共役型受容体 / 構造平衡 / 転移交差飽和法 / 過渡的複合体 / 相互作用 Less

Protein Backbone Cyclization and Application to Precise Solution Structure Analysis
- Principal Investigator
  
  生長幸之助
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
  Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
GPCRの活性化状態が薬物の親和性を規定するメカニズムの解明Principal Investigator
- Principal Investigator
  
  上田卓見
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Osaka University
  The University of Tokyo
溶液NMR法による効率的な特殊ペプチドの動的立体構造解析法の開発Principal Investigator
- Principal Investigator
  
  上田卓見
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  The University of Tokyo
薬物とGPCRの弱い相互作用が滞在時間に応じて生体応答を制御する機構の解明Principal Investigator
- Principal Investigator
  
  上田卓見
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  The University of Tokyo
Clarification of GPCR signaling regulation mechanism by NMRPrincipal Investigator
- Principal Investigator
  
  Ueda Takumi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  The University of Tokyo
動的構造平衡情報に基づく数理解析によるGPCRのシグナル制御機構の解明Principal Investigator
- Principal Investigator
  
  上田卓見
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  The University of Tokyo
核磁気共鳴法による分子夾雑系膜環境におけるG蛋白質共役型受容体の機能解明Principal Investigator
- Principal Investigator
  
  上田卓見
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  The University of Tokyo
In situ functional analyses of membrane proteins by NMR
- Principal Investigator
  
  Shimada Ichio
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  Institute of Physical and Chemical Research
  The University of Tokyo
Development of methods for studying conformational dynamics of ubiquitin-ubiquitin binding protein complexPrincipal Investigator
- Principal Investigator
  
  Ueda Takumi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokyo
高次元NMRデータ解析法の開発およびGPCRの機能解明への応用Principal Investigator
- Principal Investigator
  
  上田卓見
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  The University of Tokyo
スパース性を使った新規多次元NMRスペクトル再構成法の開発とGPCR研究への応用Principal Investigator
- Principal Investigator
  
  上田卓見
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  The University of Tokyo
医学上重要なGPCRのシグナル制御機構の構造生物学的解明Principal Investigator
- Principal Investigator
  
  上田卓見
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Structural elucidation of the mechanism underlying biased signaling of GPCRsPrincipal Investigator
- Principal Investigator
  
  Ueda Takumi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokyo
ＧＰＣＲのシグナル伝達機構の構造生物学的解明Principal Investigator
- Principal Investigator
  
  上田卓見
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Structural elucidation of the sequential signal transduction mechanism in two-component systemPrincipal Investigator
- Principal Investigator
  
  UEDA Takumi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokyo
Structural analyses of the metastable ligand-receptor interactions
- Principal Investigator
  
  SHIMADA Ichio
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  The University of Tokyo
Structural elucidation of the efficient electron transport between photosynthetic membrane proteins and electron carrierPrincipal Investigator
- Principal Investigator
  
  UEDA Takumi
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokyo
NMRを用いたフェレドキシン―キノン還元酵素の機能解明Principal Investigator
- Principal Investigator
  
  上田卓見
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokyo

[Journal Article] A High-Resolution Structural Characterization and Physicochemical Study of How a Peptoid Binds to an Oncoprotein MDM22024
- Author(s)
  Marin Yokomine, Jumpei Morimoto, Yasuhiro Fukuda, Takumi Ueda, Koh Takeuchi, Koji Umezawa,Hideo Ago, Hiroaki Matsuura, Go Ueno, Akinobu Senoo, Satoru Nagatoishi, Kouhei Tsumoto, and Shinsuke Sando
- Journal Title
  
  Chemical Science
  
  Volume: －
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K27309
[Journal Article] A High-Resolution Structural Characterization and Physicochemical Study of How a Peptoid Binds to an Oncoprotein MDM22024
- Author(s)
  Marin Yokomine, Jumpei Morimoto, Yasuhiro Fukuda, Takumi Ueda, Koh Takeuchi, Koji Umezawa,Hideo Ago, Hiroaki Matsuura, Go Ueno, Akinobu Senoo, Satoru Nagatoishi, Kouhei Tsumoto, and Shinsuke Sando
- Journal Title
  
  Chemical Science
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K18177
[Journal Article] Amide-to-ester substitution as a stable alternative to N-methylation for increasing membrane permeability in cyclic peptides.2023
- Author(s)
  Hosono Y, Uchida S, Shinkai M, Townsend CE, Kelly CN, Naylor MR, Lee HW, Kanamitsu K, Ishii M, Ueki R, Ueda T, Takeuchi K, Sugita M, Akiyama Y, Lokey SR, Morimoto J, Sando S.
- Journal Title
  
  Nat. Commun.
  
  Volume: 14 Issue: 1 Pages: 1416-1416
- DOI
  10.1038/s41467-023-36978-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-21H05509, KAKENHI-PROJECT-20H03375, KAKENHI-PROJECT-23K24939, KAKENHI-PROJECT-22K18374
[Journal Article] Ultrafast water permeation through nanochannels with a densely fluorous interior surface.2022
- Author(s)
  Itoh Y, Chen S, Hirahara R, Konda T, Aoki T, Ueda T, Shimada I, Cannon JJ, Shao C, Shiomi J, Tabata KV, Noji H, Sato K, Aida T.
- Journal Title
  
  Science
  
  Volume: 376 Issue: 6594 Pages: 738-743
- DOI
  10.1126/science.abd0966
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-21H05509, KAKENHI-PROJECT-20H03375, KAKENHI-PROJECT-20K20448, KAKENHI-PROJECT-20J22759, KAKENHI-PROJECT-18H05260, KAKENHI-PROJECT-21H01903
[Journal Article] Residue-based program of a β-peptoid twisted strand shape via a cyclopentane constraint2022
- Author(s)
  Kim J, Kobayashi H, Yokomine M, Shiratori Y, Ueda T, Takeuchi K, Umezawa K, Kuroda D, Tsumoto K, Morimoto J, Sando S.
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 20 Issue: 35 Pages: 6994-7000
- DOI
  10.1039/d2ob01300b
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21H05509, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-20H03375, KAKENHI-PROJECT-20H03378
[Journal Article] Oligo(N‐methylalanine) as a Peptide‐Based Molecular Scaffold with a Minimal Structure and High Density of Functionalizable Sites2022
- Author(s)
  Yokomine Marin、Morimoto Jumpei、Fukuda Yasuhiro、Shiratori Yota、Kuroda Daisuke、Ueda Takumi、Takeuchi Koh、Tsumoto Kouhei、Sando Shinsuke
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 61 Issue: 14 Pages: 6994-7000
- DOI
  10.1002/anie.202200119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21494, KAKENHI-PROJECT-19H03522, KAKENHI-PUBLICLY-21H05509, KAKENHI-PROJECT-20H03375, KAKENHI-PROJECT-20H03378, KAKENHI-PROJECT-19H04202
[Journal Article] Function-related dynamics of GPCRs2022
- Author(s)
  Ueda Takumi、Imai Shunsuke、Shimada Ichio
- Journal Title
  
  Journal of Magnetic Resonance
  
  Volume: 336 Pages: 107164-107164
- DOI
  10.1016/j.jmr.2022.107164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02619, KAKENHI-PROJECT-17H06097, KAKENHI-PUBLICLY-21H05509, KAKENHI-PROJECT-20H03375
[Journal Article] Function-Related Conformational Dynamics of GPCRs Revealed by Solution NMR2022
- Author(s)
  UEDA Takumi、KOFUKU Yutaka、TAKEUCHI Koh、IMAI Shunsuke、SHIRAISHI Yutaro、SHIMADA Ichio
- Journal Title
  
  Nihon Kessho Gakkaishi
  
  Volume: 64 Issue: 4 Pages: 279-284
- DOI
  10.5940/jcrsj.64.279
- ISSN
  0369-4585, 1884-5576
- Year and Date
  2022-12-15
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-22K15052, KAKENHI-PUBLICLY-21H05509, KAKENHI-PROJECT-20H03375, KAKENHI-PROJECT-21H02619
[Journal Article] Activation mechanism of the μ-opioid receptor by an allosteric modulator.2022
- Author(s)
  Kaneko S, Imai S, Asao N, Kofuku Y, Ueda T, Shimada I.
- Journal Title
  
  Proc. Natl. Acad. Sci. U. S. A.
  
  Volume: 119 Issue: 16
- DOI
  10.1073/pnas.2121918119
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-21H05509, KAKENHI-PROJECT-20H03375, KAKENHI-PROJECT-20K21473, KAKENHI-PROJECT-17H06097, KAKENHI-PROJECT-23K21289
[Journal Article] Function-Related Dynamics in Multi-Spanning Helical Membrane Proteins Revealed by Solution NMR2021
- Author(s)
  Takeuchi Koh、Kofuku Yutaka、Imai Shunsuke、Ueda Takumi、Tokunaga Yuji、Toyama Yuki、Shiraishi Yutaro、Shimada Ichio
- Journal Title
  
  Membranes
  
  Volume: 11 Issue: 8 Pages: 604-604
- DOI
  10.3390/membranes11080604
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21494, KAKENHI-PUBLICLY-20H04722, KAKENHI-PROJECT-18H02393, KAKENHI-PROJECT-21H02619, KAKENHI-PROJECT-20K21473, KAKENHI-PROJECT-17H06097, KAKENHI-PUBLICLY-21H05509, KAKENHI-PROJECT-20H03375, KAKENHI-PROJECT-20H03378, KAKENHI-PROJECT-23K21289
[Journal Article] Biphasic activation of β-arrestin 1 upon interaction with a GPCR revealed by methyl-TROSY NMR2021
- Author(s)
  Shiraishi Yutaro、Kofuku Yutaka、Ueda Takumi、Pandey Shubhi、Dwivedi-Agnihotri Hemlata、Shukla Arun K.、Shimada Ichio
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 7158-7158
- DOI
  10.1038/s41467-021-27482-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21473, KAKENHI-PROJECT-17H06097, KAKENHI-PUBLICLY-21H05509, KAKENHI-PROJECT-20H03375, KAKENHI-PROJECT-23K21289
[Journal Article] Activation of adenosine A2A receptor by lipids from docosahexaenoic acid revealed by NMR2020
- Author(s)
  Takuya Mizumura, Keita Kondo, Masatoshi Kurita, Yutaka Kofuku, Mei Natsume, Shunsuke Imai, Yutaro Shiraishi, Takumi Ueda, Ichio Shimada
- Journal Title
  
  Science Advances
  
  Volume: 6 Issue: 12
- DOI
  10.1126/sciadv.aay8544
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H04540, KAKENHI-PUBLICLY-19H04946, KAKENHI-PUBLICLY-19H04951, KAKENHI-PROJECT-17H04999, KAKENHI-PROJECT-17H06097, KAKENHI-PROJECT-20H03375
[Journal Article] Structural equilibrium underlying ligand-dependent activation of b2-adrenoreceptor2020
- Author(s)
  Shunsuke Imai, Tomoki Yokomizo, Yutaka Kofuku, Yutaro Shiraishi, Takumi Ueda, Ichio Shimada
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 16 Issue: 4 Pages: 430-439
- DOI
  10.1038/s41589-019-0457-5
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04540, KAKENHI-PUBLICLY-19H04946, KAKENHI-PUBLICLY-19H04951, KAKENHI-PROJECT-17H04999, KAKENHI-PROJECT-17H06097, KAKENHI-PROJECT-20H03375
[Journal Article] Function-related conformational dynamics of G protein-coupled receptors revealed by NMR2019
- Author(s)
  Takumi Ueda, Yutaka Kofuku, Junya Okude, Shunsuke Imai, Yutaro Shiraishi, Ichio Shimada
- Journal Title
  
  Biophysical Reviews
  
  Volume: 11 Issue: 3 Pages: 409-418
- DOI
  10.1007/s12551-019-00539-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H04540, KAKENHI-PUBLICLY-19H04951, KAKENHI-PROJECT-17H06097
[Journal Article] NMR 解析の最前線：分子間相互作用と動的構造2019
- Author(s)
  上田卓見、嶋田一夫
- Journal Title
  
  月刊細胞
  
  Volume: 51 Pages: 596-599
- Data Source
  KAKENHI-PROJECT-17H06097
[Journal Article] NMR Studies of Function-related Conformational Equilibria of GPCRs2019
- Author(s)
  上田卓見、嶋田一夫
- Journal Title
  
  Seibutsu Butsuri
  
  Volume: 59 Issue: 4 Pages: 181-187
- DOI
  10.2142/biophys.59.181
- NAID
  130007683541
- ISSN
  0582-4052, 1347-4219
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04540, KAKENHI-PUBLICLY-19H04951, KAKENHI-PROJECT-17H06097
[Journal Article] NMR 解析の最前線：分子間相互作用と動的構造2019
- Author(s)
  上田卓見、嶋田一夫
- Journal Title
  
  月刊細胞
  
  Volume: 51 Pages: 596-599
- Data Source
  KAKENHI-PUBLICLY-18H04540
[Journal Article] NMR 解析の最前線：分子間相互作用と動的構造2019
- Author(s)
  上田卓見、嶋田一夫
- Journal Title
  
  月刊細胞
  
  Volume: 51 Pages: 596-599
- Data Source
  KAKENHI-PUBLICLY-19H04951
[Journal Article] Phosphorylation-induced conformation of β2-adrenoceptor related to arrestin recruitment revealed by NMR2018
- Author(s)
  Yutaro Shiraishi, Mei Natsume, Yutaka Kofuku, Shunsuke Imai, Kunio Nakata, Toshimi Mizukoshi, Takumi Ueda, Hideo Iwai, Ichio Shimada
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 164-164
- DOI
  10.1038/s41467-017-02632-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08191, KAKENHI-PROJECT-17H06097, KAKENHI-PUBLICLY-16H01353, KAKENHI-PUBLICLY-16H01531, KAKENHI-PROJECT-17H04999, KAKENHI-PROJECT-17J11420
[Journal Article] Endogenous Membrane Receptor Labeling by Reactive Cytokines and Growth Factors to Chase Their Dynamics in Live Cells2018
- Author(s)
  Takaoka Yousuke、Uchinomiya Shohei、Kobayashi Daichi、Endo Masataka、Hayashi Takahiro、Fukuyama Yoshiaki、Hayasaka Haruko、Miyasaka Masayuki、Ueda Takumi、Shimada Ichio、Hamachi Itaru
- Journal Title
  
  Chem
  
  Volume: 4 Issue: 6 Pages: 1451-1464
- DOI
  10.1016/j.chempr.2018.03.021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08481, KAKENHI-PLANNED-17H06348, KAKENHI-PUBLICLY-18H04540, KAKENHI-PROJECT-16K08191, KAKENHI-PROJECT-17H06097
[Journal Article] Deuteration and Selective Labeling of Alanine Methyl Groups of β 2-Adrenergic Receptor Expressed in a Baculovirus-Insect Cell Expression System2018
- Author(s)
  Yutaka Kofuku, Tomoki Yokomizo, Shunsuke Imai, Yutaro Shiraishi, Mei Natsume, Hiroaki Itoh, Masayuki Inoue, Kunio Nakata, Shunsuke Igarashi, Hideyuki Yamaguchi, Toshimi Mizukoshi, Ei-Ichiro Suzuki, Takumi Ueda, Ichio Shimada
- Journal Title
  
  Journal of Biomolecular NMR
  
  Volume: 印刷中 Issue: 3 Pages: 185-192
- DOI
  10.1007/s10858-018-0174-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08191, KAKENHI-PROJECT-17K15421, KAKENHI-PROJECT-17H06097, KAKENHI-PUBLICLY-16H01353, KAKENHI-PUBLICLY-16H01531, KAKENHI-PROJECT-17H06110, KAKENHI-PROJECT-17H04999, KAKENHI-PROJECT-17J11420, KAKENHI-PUBLICLY-18H04540
[Journal Article] GPCR drug discovery: integrating solution NMR data with crystal and cryo-EM structures2018
- Author(s)
  Shimada Ichio、Ueda Takumi、Kofuku Yutaka、Eddy Matthew T.、Wuthrich Kurt
- Journal Title
  
  Nature Reviews Drug Discovery
  
  Volume: 18 Issue: 1 Pages: 59-82
- DOI
  10.1038/nrd.2018.180
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04540, KAKENHI-PROJECT-17H04999, KAKENHI-PROJECT-16K08191, KAKENHI-PROJECT-17H06097
[Journal Article] 特集いかに創薬を進めるか NMRで標的タンパク質の機能から創薬を2018
- Author(s)
  上田　卓見、嶋田　一夫
- Journal Title
  
  生体の科学
  
  Volume: 69 Issue: 4 Pages: 315-319
- DOI
  10.11477/mf.2425200823
- ISSN
  0370-9531, 1883-5503
- Year and Date
  2018-08-15
- Data Source
  KAKENHI-PROJECT-17H06097
[Journal Article] Dynamic domain arrangement of CheA-CheY complex regulates bacterial thermotaxis, as revealed by NMR2017
- Author(s)
  YuYuichi Minato, Takumi Ueda, Asako Machiyama, Hideo Iwai, Ichio Shimada
- Journal Title
  
  as revealed by NMR Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 16462-16462
- DOI
  10.1038/s41598-017-16755-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08191, KAKENHI-PROJECT-17H06097, KAKENHI-PUBLICLY-16H01531
[Journal Article] Conductance of P2X4 receptor is determined by conformational equilibrium in the transmembrane region2016
- Author(s)
  Minato Y, Suzuki S , Hara T, Kofuku Y, Kasuya G, Fujiwara Y, Igarashi S, Suzuki E, Nureki O, Hattori M, Ueda T, Shimada I
- Journal Title
  
  Proc. Natl. Acad. Sci.
  
  Volume: 発行中 Issue: 17 Pages: 4741-4746
- DOI
  10.1073/pnas.1600519113
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460033, KAKENHI-PROJECT-25670108, KAKENHI-PUBLICLY-26120506, KAKENHI-PUBLICLY-16H01389, KAKENHI-PROJECT-26291030, KAKENHI-PROJECT-15K18843, KAKENHI-PROJECT-16K08191, KAKENHI-PROJECT-16K15180, KAKENHI-PUBLICLY-16H01353
[Journal Article] Conductance of P2X4 purinergic receptor is determined by conformational equilibrium in the transmembrane region2016
- Author(s)
  Yuichi Minato, Shiho Suzuki, Tomoaki Hara, Yutaka Kofuku, Go Kasuya, Yuichiro Fujiwara, Shunsuke Igarashi, Ei-ichiro Suzuki, Osamu Nureki, Motoyuki Hattori, Takumi Ueda, Ichio Shimada
- Journal Title
  
  Proc. Natl. Acad. Sci. U. S. A.
  
  Volume: 113 Pages: 4741-4746
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01531
[Journal Article] Identification of a Conformational Equilibrium That Determines the Efficacy and Functional Selectivity of the μ-Opioid Receptor.2015
- Author(s)
  Junya Okude, Takumi Ueda, Yutaka Kofuku, Motohiko Sato, Naoyuki Nobuyama, Keita Kondo, Yutaro Shiraishi, Takuya Mizumura, Kento Onishi, Mei Natsume, Masahiro Maeda, Hideki Tsujishita, Takefumi Kuranaga, Masayuki Inoue, Ichio Shimada
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 21 Issue: 52 Pages: 15771-15776
- DOI
  10.1002/anie.201508794
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K18843, KAKENHI-PROJECT-26253003, KAKENHI-PROJECT-15J12409, KAKENHI-PROJECT-25460033, KAKENHI-PUBLICLY-26120506
[Journal Article] Development of a method for reconstruction of crowded NMR spectra from undersampled time-domain data2015
- Author(s)
  Ueda T, Yoshiura C, Matsumoto M, Kofuku Y, Okude J, Kondo K, Shiraishi Y, Takeuchi K, Shimada I
- Journal Title
  
  J. Biomol. NMR
  
  Volume: 印刷中 Issue: 1 Pages: 31-41
- DOI
  10.1007/s10858-015-9908-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-25121708, KAKENHI-PROJECT-25460033, KAKENHI-PROJECT-26893041, KAKENHI-PROJECT-15K18843, KAKENHI-PUBLICLY-26120506, KAKENHI-PROJECT-15J12409
[Journal Article] Elucidation of the CCR1- and CCR5-binding modes of MIP-1α by application of an NMR spectra reconstruction method to the transferred cross-saturation experiments.2015
- Author(s)
  Chie Yoshiura, Takumi Ueda, Yutaka Kofuku, Masahiko Matsumoto, Junya Okude, Keita Kondo, Yutaro Shiraishi, Ichio Shimada
- Journal Title
  
  Journal of Biomolecular NMR
  
  Volume: 63 Issue: 4 Pages: 333-340
- DOI
  10.1007/s10858-015-9992-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K18843, KAKENHI-PROJECT-15J12409, KAKENHI-PROJECT-25460033, KAKENHI-PUBLICLY-26120506
[Journal Article] Cross-saturation and transferred cross-saturation experiments2014
- Author(s)
  Ueda T, Takeuchi K, Nishida N, Stampoulis P, Kofuku Y, Osawa M, Shimada I
- Journal Title
  
  Q Rev Biophys
  
  Volume: 47 Issue: 2 Pages: 143-187
- DOI
  10.1017/s0033583514000043
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-21121001, KAKENHI-PROJECT-24590048, KAKENHI-PROJECT-24770090, KAKENHI-PUBLICLY-25121707, KAKENHI-PUBLICLY-25121708, KAKENHI-PROJECT-25460033, KAKENHI-PLANNED-26119005
[Journal Article] Structure-based approach to improve a small-molecule inhibitor by the use of a competitive peptide ligand.2014
- Author(s)
  Ono K, Takeuchi K, Ueda H, Morita Y, Tanimura R, Shimada I, Takahashi H.
- Journal Title
  
  Angew Chem Int Ed Engl
  
  Volume: 53 Issue: 10 Pages: 2597-2597
- DOI
  10.1002/anie.201310749
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-21121001, KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-23570146, KAKENHI-PROJECT-24370048, KAKENHI-PUBLICLY-25121743
[Journal Article] Functional dynamics of cell surface membrane proteins2014
- Author(s)
  Nishida N, Osawa M, Takeuchi K, Imai S, Stampoulis P, Kofuku Y, Ueda T, Shimada I
- Journal Title
  
  J Magn Reson
  
  Volume: 241 Pages: 86-96
- DOI
  10.1016/j.jmr.2013.11.007
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-21121001, KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-24590048, KAKENHI-PROJECT-24770090, KAKENHI-PUBLICLY-25121707, KAKENHI-PUBLICLY-25121708, KAKENHI-PUBLICLY-25121743, KAKENHI-PROJECT-25460033, KAKENHI-PLANNED-26119005
[Journal Article] Functional dynamics of deuterated β2 -adrenergic receptor in lipid bilayers revealed by NMR spectroscopy2014
- Author(s)
  Kofuku Y, Ueda T, Okude J, Shiraishi Y, Kondo K, Mizumura T, Suzuki S, Shimada I
- Journal Title
  
  Angew Chem Int Ed Engl
  
  Volume: 53 Issue: 49 Pages: 13376-13379
- DOI
  10.1002/anie.201406603
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-21121001, KAKENHI-PUBLICLY-25121708, KAKENHI-PROJECT-25460033, KAKENHI-PROJECT-26893041, KAKENHI-PUBLICLY-26120506
[Journal Article] Functional dynamics of proteins revealed by NMR2012
- Author(s)
  Masanori Osawa, Koh Takeuchi, Takumi Ueda, Noritaka Nishida, and Ichio Shimada
- Journal Title
  
  Curr. Opin. Struct. Biol.
  
  Volume: 22 Pages: 660-669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790042
[Journal Article] Structural Basis of Efficient Electron Transport between Photosyn thetic Membrane Proteins and Plastocyanin in Spinach Revealed using Nuclear Magnetic Resonance2012
- Author(s)
  Takumi Ueda, Naoko Nomoto, Masamichi Koga, Hiroki Ogasa, Yuuta Ogawa, Masahiko Matsumoto, Pavlos Stampoulis, Koji Sode, Hiroaki Terasawa and Ichio Shimada
- Journal Title
  
  Plant Cell
  
  Volume: 24 Issue: 10 Pages: 4173-4186
- DOI
  10.1105/tpc.112.102517
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J00159, KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-23790042, KAKENHI-PUBLICLY-23121511, KAKENHI-ORGANIZER-21121001
[Journal Article] Structural basis of efficient electron transport between photosynthetic membrane proteins and plastocyanin in spinach revealed using nuclear magnetic resonance2012
- Author(s)
  Takumi Ueda, Naoko Nomoto, Masamichi Koga, Hiroki Ogasa, Yuuta Ogawa, Masahiko Matsumoto, Pavlos Stampoulis, Koji Sode, Hiroaki Terasawa, and Ichio Shimada
- Journal Title
  
  Plant Cell
  
  Volume: 24 Pages: 4173-4186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790042
[Journal Article] Atypical membrane-embedded PI(3,4)P2 binding site on p47phox PX domain revealed by NMR2012
- Author(s)
  Pavlos Stampoulis, Takumi Ueda, Masahiko Matsumoto, Hiroaki Terasawa, Kei Miyano, Hideki Sumimoto, Ichio Shimada
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23121511
[Journal Article] Efficacy of the -2-adrenergic receptor is determined byconformational equilibrium in thetransmembrane region2012
- Author(s)
  Yutaka Kofuku, Takumi Ueda, JunyaOkude, Yutaro Shiraishi, Keita Kondo,Masahiro Maeda, Hideki Tsujishita, andIchio Shimada
- Journal Title
  
  Nature Commun.
  
  Volume: 3 Pages: 1045-1045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790042
[Journal Article] Atypical membrane-embedded p47^<phox> PI(3,4)P_2 binding site on PX domain revealed by NMR2012
- Author(s)
  Stampoulis P, Ueda T, Matsumoto M, Terasawa H, Miyano K, Sumimoto H, and Shimada I
- Journal Title
  
  J. Biol. Chem
  
  Volume: 287 Issue: 21 Pages: 17848-17859
- DOI
  10.1074/jbc.m111.332874
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117002, KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-21390084, KAKENHI-PROJECT-23790042, KAKENHI-PROJECT-23790338, KAKENHI-ORGANIZER-21121001
[Journal Article] Segmental isotopic labeling of a 140 kDadimeric multi-domain protein CheA from Escherichia Coli by Expressed Protein Ligation and Protein Trans-Splicing2012
- Author(s)
  Yuichi Minato, Takumi Ueda, Asako Machiyama, Ichio Shimada, Hideo Iwai
- Journal Title
  
  Journal of Biomolecular NMR
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790042
[Journal Article] Efficacy of the β2-adrenergic receptor is determined by conformational equilibrium in the transmembrane region2012
- Author(s)
  Kofuku Y, Ueda T, Okude J, Shiraishi Y, Kondo K, Maeda M, Tsujishita H, Shimada I
- Journal Title
  
  Nat Commun.
  
  Volume: 3 Issue: 1 Pages: 1045-1045
- DOI
  10.1038/ncomms2046
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21121002, KAKENHI-PUBLICLY-23121511, KAKENHI-ORGANIZER-21121001
[Journal Article] Segmental isotopic labeling of a 140 kDadimeric multi-domain protein CheA from Escherichia Coli by Expressed Protein Ligation and Protein Trans-Splicing2012
- Author(s)
  Yuichi Minato, Takumi Ueda, Asako Machiyama, Ichio Shimada, Hideo Iwai
- Journal Title
  
  Journal of Biomolecular NMR
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23121511
[Journal Article] Segmental isotopic labeling of a 140 kDa dimeric multi-domain protein CheA from Escherichia coli by expressed protein ligation and protein trans-splicing2012
- Author(s)
  Minato Y, Ueda T, Machiyama A, Shimada l, Iwai H
- Journal Title
  
  Journal of Biomolecular NMR
  
  Volume: 53 Issue: 3 Pages: 191-207
- DOI
  10.1007/s10858-012-9628-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J11124, KAKENHI-PLANNED-21121002, KAKENHI-ORGANIZER-21121001
[Journal Article] Atypical membrane-embedded phosphatidylinositol3,4-bisphosphate (PI(3,4)P2)-binding site on p47phox Phox homology (PX) domain revealed by NMR.2012
- Author(s)
  Pavlos Stampoulis, Takumi Ueda, Masahiko Matsumoto, Hiroaki Terasawa, and Ichio Shimada
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 287 Pages: 17848-17859
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790042
[Journal Article] Functional Equilibrium of the KcsA Structure Revealed by NMR2012
- Author(s)
  Imai S., Osawa M., Mita K., Toyonaga S., Machiyama A., Ueda T., Takeuchi K., Oiki S., and Ichio Shimada
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 287 Pages: 39634-39641
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790042
[Journal Article] Segmental isotopic labeling of a 140 kDa dimeric multi-domain protein CheA from Escherichia coli by expressed protein ligation and protein trans-splicing2012
- Author(s)
  Yuichi Minato, Takumi Ueda, Asako Machiyama, Ichio Shimada, and Hideo Iwai
- Journal Title
  
  J.Biomol. NMR
  
  Volume: 53 Pages: 191-207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790042
[Journal Article] Functional equilibrium of the KcsA structure revealed by NMR2012
- Author(s)
  Imai S, Osawa M, Mita K, Toyonaga S, Machiyama A, Ueda T, Takeuchi K, Oiki S, Shimada I.
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Issue: 47 Pages: 39634-39641
- DOI
  10.1074/jbc.m112.401265
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-23370067, KAKENHI-PROJECT-23790064, KAKENHI-PROJECT-24590048, KAKENHI-PROJECT-24659096, KAKENHI-PROJECT-24659097, KAKENHI-PUBLICLY-23107708, KAKENHI-PUBLICLY-23107735, KAKENHI-ORGANIZER-21121001
[Journal Article] Functional dynamics of proteins revealed by solution NMR2012
- Author(s)
  Osawa M, Takeuchi K, Ueda T, Nishida N, Shimada I.
- Journal Title
  
  Curr Opin Struct Biol
  
  Volume: 22 Issue: 5 Pages: 660-669
- DOI
  10.1016/j.sbi.2012.08.007
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-23790064, KAKENHI-PROJECT-24590048, KAKENHI-PROJECT-24770090, KAKENHI-PUBLICLY-23107708, KAKENHI-PUBLICLY-23107735, KAKENHI-ORGANIZER-21121001
[Journal Article] The Atmospheric Scanning Electron Microscope with open sample space observes dynamic phenomena in liquid or gas2011
- Author(s)
  Mitsuo Suga, Hidetoshi Nishiyama, Yuji Konyuba, Shinnosuke Iwamatsu, Yoshiyuki Watanabe, Chie Yoshiura, Takumi Ueda, andChikara Sato
- Journal Title
  
  Ultramicroscopy
  
  Volume: 111 Pages: 1650-1658
- Data Source
  KAKENHI-PROJECT-23790042
[Journal Article] The Atmospheric Scanning Electron Microscope with open sample space observes dynamic phenomena in liquid or gas2011
- Author(s)
  Mitsuo Suga, Hidetoshi Nishiyama, Yuji Konyuba, Shinnosuke Iwamatsu, Yoshiyuki Watanabe, Chie Yoshiura, Takumi Ueda, Chikara Sato
- Journal Title
  
  Ultramicroscopy
  
  Volume: 111 Pages: 1650-1658
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23121511
[Journal Article] Theoretical analyses of the transferred cross-saturation method2010
- Author(s)
  Masahiko Matsumoto, Takumi Ueda, Ichio Shimada
- Journal Title
  
  J.Magn.Reson.
  
  Volume: 205 Pages: 114-124
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21121002
[Journal Article] Structural Basis for Platelet Anti-aggregation by AT1-Receptor Antagonist Losartan via Glycoprotein VI2010
- Author(s)
  Katsuki Ono, Hiroshi Ueda, Yoshitaka Yoshizawa, Daisuke Akazawa, Ryuji Tanimura, Ichio Shimada, Hideo Takahashi
- Journal Title
  
  J.Med.Chem.
  
  Volume: 53 Pages: 1917-1922
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21121002
[Journal Article] NMR analyses of the interaction between CCR5 and its ligand using functional reconstitution of CCR5 in lipid bilayers2010
- Author(s)
  Yoshiura C, Kofuku Y, Ueda T, Mase Y, Yokogawa M, Osawa M, Terashima Y, Matsushima K, Shimada I
- Journal Title
  
  J Am Chem Soc.
  
  Volume: 132(19) Issue: 19 Pages: 6768-77
- DOI
  10.1021/ja100830f
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-21590040
[Journal Article] Theoretical analyses of the transferred cross-saturation method, Epub 20102010
- Author(s)
  Matsumoto M, Ueda T, Shimada I
- Journal Title
  
  J Magn Reson.
  
  Volume: 205(1) Issue: 1 Pages: 114-24
- DOI
  10.1016/j.jmr.2010.04.011
- Data Source
  KAKENHI-PLANNED-21121002
[Journal Article] theoretical analyes of the transferred cross-saturation method2010
- Author(s)
  Masahiko Matsumoto, Takumi Ueda, Ichio Shimada
- Journal Title
  
  J. Magn. Reson. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790029
[Journal Article] NMR analyses of the interaction between CCR5 and its ligand using functional reconstitution of CCR5 in lipid bilayers2010
- Author(s)
  Chie Yoshiura, Yutaka Kofuku, Takumi Ueda, Yoko Mase, Mariko Yokogawa, Masanori Osawa, Yuya Terashima, Kouji Matsushima, Ichio Shimada
- Journal Title
  
  J. Am. Chem. Soc. Vol.132
  
  Pages: 6768-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790029
[Journal Article] NMR analyses of the interaction between CCR5 and its ligand using functional reconstitution of CCR5 in lipid bilayers2010
- Author(s)
  Chie Yoshiura, Yutaka Kofuku, Takumi Ueda, Yoko Mase, Mariko Yokogawa, Masanori Osawa, Yuya Terashima, Kouji Matsushima, Ichio Shimada
- Journal Title
  
  J.Am.Chem.Soc.
  
  Volume: 132 Pages: 6768-6777
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21121002
[Journal Article] Cross-saturation and transferred cross-saturation experiments2009
- Author(s)
  Ichio Shimada, Takumi Ueda, Masahiko Matsumoto, Masayo shi Sakakura, Masanori. Osaw a, Koh Takeuchi, Noritaka N ishida, Hideo Takahashi
- Journal Title
  
  Progress in Nuclear Magnetic Resonance Spectroscopy 54
  
  Pages: 123-140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790029
[Journal Article] Structural Basis of the Interaction between Chemokine Stromal Cell-derived Factor-1/CXCL12 and Its G-protein-coupled Receptor CXCR42009
- Author(s)
  Kofuku Y, Yoshiura C, Ueda T, Terasawa H, Hirai T, Tominaga S, Hirose M, Maeda Y, Takahashi H, Terashima Y, Matsushima K, Shimada I
- Journal Title
  
  J Biol Chem.
  
  Volume: 284(50) Issue: 50 Pages: 35240-50
- DOI
  10.1074/jbc.m109.024851
- Data Source
  KAKENHI-PLANNED-21121002
[Journal Article] Structural basis of the interaction between chemokine stromal cell-derived factor-1/CXCL12 and its G-protein-coupled receptor CXCR42009
- Author(s)
  Yutaka Kofuku, Chie Yoshiura, Takumi Ueda, Hiroaki Terasawa, Takahiro Hirai, Sae Tominaga, Masako Hirose, Yoshitake Maeda, Hideo Takahashi, Yuya Terashima, Kouji Matsushima, Ichio Shimada
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages: 35240-35250
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790029
[Journal Article] High-throughput screening of optimal solution conditions for structural biological studies by fluorescence correlation spectroscopy2009
- Author(s)
  Toshihiko Sugiki, Yutaka Kofuku, Takumi Ueda, Ichio Shimada, Hideo Takahashi
- Journal Title
  
  Protein Science 18
  
  Pages: 1115-1120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790029
[Journal Article] Structural basis of the interaction between chemokine stromal cell-derived factor-1/CXCL12 and its G-protein-coupled receptor CXCR42009
- Author(s)
  Yutaka Kofuku, Chie Yoshiura, Takumi Ueda, Hiroaki Terasawa, Takahiro Hirai, Sae Tominaga, Masako Hirose, Yoshitake Maeda, Hideo Takahashi, Yuya Terashima, Kouji Matsushima, Ichio Shimada
- Journal Title
  
  J. Biol. Chem. Vol.284
  
  Pages: 35240-35250
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790029
[Journal Article] High-throughput screening of optimal solution conditions for structural biological studies by fluorescence correlation spectroscopy.2009
- Author(s)
  Toshihiko Sugiki, Yutaka Kofuku, Takumi Ueda, Ichio Shimada, Hideo Takahashi
- Journal Title
  
  Protein Science Vol.18
  
  Pages: 1115-1120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790029
[Journal Article] Cross-saturation and transferred cross-saturation experiments2008
- Author(s)
  Ichio Shimada, Takumi Ueda, Masahiko Matsumoto, Masayoshi Sakakura, Masanori Osawa, Koh Takeuchi, Noritaka Nishida, Hideo Takahashi
- Journal Title
  
  Prog. Nuc. Mag. Res. Spectroscopy Vol.54
  
  Pages: 123-140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790029
[Journal Article] NMRによるソフトな分子間相互作用解析法の開発ど光合成明反応電子移動蛋白質問相互作用への応用2008
- Author(s)
  松本昌彦, 上田卓見, 嶋田一夫
- Journal Title
  
  生化学 80
  
  Pages: 959-971
- Data Source
  KAKENHI-PROJECT-20790029
[Presentation] アデノシンA2A受容体とリガンドの滞在時間を規定する構造基盤の解明2023
- Author(s)
  上田　卓見
- Organizer
  第61回NMR討論会
- Data Source
  KAKENHI-PUBLICLY-21H05509
[Presentation] 交換モンテカルロ法を利用した、タンパク質の動的構造平衡と機能の解明2023
- Author(s)
  上田卓見、今井駿輔、横溝智貴、猪野麻巳子、白石勇太郎、幸福裕、竹内恒、嶋田一夫
- Organizer
  第62回NMR討論会
- Data Source
  KAKENHI-PROJECT-23K27309
[Presentation] Clarification of the GPCR signaling mechanism based on the function-related conformational dynamics2023
- Author(s)
  上田　卓見
- Organizer
  第61回NMR討論会
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H05509
[Presentation] 交換モンテカルロ法を利用した、タンパク質の動的構造平衡と機能の解明2023
- Author(s)
  上田卓見、今井駿輔、横溝智貴、猪野麻巳子、白石勇太郎、幸福裕、竹内恒、嶋田一夫
- Organizer
  第62回NMR討論会
- Data Source
  KAKENHI-PROJECT-23K18177
[Presentation] Clarification of the GPCR signaling mechanism based on the function-related conformational dynamics2022
- Author(s)
  上田　卓見
- Organizer
  第61回NMR討論会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03375
[Presentation] アデノシンA2A受容体とリガンドの滞在時間を規定する構造基盤の解明2022
- Author(s)
  上田　卓見
- Organizer
  第61回NMR討論会
- Data Source
  KAKENHI-PROJECT-20H03375
[Presentation] Conductance of P2X4 receptor is determined by conformational equilibrium in the transmembrane region2019
- Author(s)
  Takumi Ueda, Ichio Shimada
- Organizer
  The 8th Asia-Pacific NMR symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06097
[Presentation] Conductance of P2X4 receptor is determined by conformational equilibrium in the transmembrane region2019
- Author(s)
  Takumi Ueda, Ichio Shimada
- Organizer
  The 8th Asia-Pacific NMR symposium
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04951
[Presentation] Conductance of P2X4 receptor is determined by conformational equilibrium in the transmembrane region2019
- Author(s)
  Takumi Ueda, Ichio Shimada
- Organizer
  The 8th Asia-Pacific NMR symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04540
[Presentation] Gタンパク質共役型受容体のシグナル伝達制御機構の解明2019
- Author(s)
  白石勇太郎夏目芽依幸福裕今井駿輔中田國夫水越利巳上田卓見岩井秀夫嶋田一夫
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17H06097
[Presentation] 区分同位体標識を用いたβ2アドレナリン受容体のリン酸化によるシグナル制御機構の解明2018
- Author(s)
  白石勇太郎、夏目芽依、幸福裕、今井駿輔、中田國夫、水越利巳、上田卓見、岩井秀夫、嶋田一夫
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H06097
[Presentation] β2アドレナリン受容体のリン酸化によるシグナル制御機構の解明2018
- Author(s)
  夏目芽依白石勇太郎幸福裕今井駿輔中田國夫水越利巳上田卓見岩井秀夫嶋田一夫
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17H06097
[Presentation] アラニン側鎖メチル基を観測対象としたβ2-アドレナリン受容体のシグナル伝達機構の解明2018
- Author(s)
  横溝智貴、今井俊輔、幸福裕、上田卓見、白石勇太郎、夏目芽依、中田國夫、五十嵐俊介、水越利巳、鈴木榮一郎、嶋田一夫
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H06097
[Presentation] β2アドレナリン受容体のリン酸化によるシグナル制御機構の解明2018
- Author(s)
  夏目芽依、白石勇太郎、幸福裕、今井駿輔、中田國夫、水越利巳、上田卓見、岩井秀夫、嶋田一夫
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H06097
[Presentation] 昆虫細胞発現系におけるアラニン選択的安定同位体標識法の開発と脂質二重膜中のβ2-アドレナリン受容体への応用2018
- Author(s)
  中田國夫、五十嵐俊介、幸福裕、上田卓見、白石勇太郎、夏目芽依、横溝智貴、今井俊輔、水越利巳、鈴木榮一郎、嶋田一夫
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H06097
[Presentation] 昆虫細胞発現系における安定同位体標識法の開発とGタンパク質共役型受容体のNMR解析2018
- Author(s)
  幸福裕、上田卓見、奥出順也、白石勇太郎、夏目芽依、横溝智貴、今井俊輔、近藤啓太、水村拓也、鈴木志歩、伊藤寛晃、井上将行、中田國夫、五十嵐俊介、山口秀幸、水越利巳、鈴木栄一郎、嶋田一夫
- Organizer
  第20回若手NMR研究会
- Data Source
  KAKENHI-PROJECT-17H06097
[Presentation] NMR法により解明した、マルチドメイン蛋白質複合体CheA-CheYの動的ドメイン間相互作用による走温性制御機構2018
- Author(s)
  上田卓見、湊雄一、町山麻子、岩井秀夫、嶋田一夫
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H06097
[Presentation] 区分同位体標識を用いたβ2アドレナリン受容体のリン酸化によるシグナル制御機構の解明2018
- Author(s)
  白石勇太郎夏目芽依幸福裕今井駿輔中田國夫水越利巳上田卓見岩井秀夫嶋田一夫
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17H06097
[Presentation] 安定同位体標識法の応用による、蛋白質の動的構造の解明2017
- Author(s)
  上田　卓見、嶋田　一夫
- Organizer
  第56回NMR討論会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08191
[Presentation] 安定同位体標識法の応用による、蛋白質の動的構造の解明2017
- Author(s)
  上田卓見、嶋田一夫
- Organizer
  第56回NMR討論会
- Invited
- Data Source
  KAKENHI-PROJECT-17H06097
[Presentation] Conductance of P2X4 purinergic receptor is determined by conformational equilibrium in the transmembrane region2017
- Author(s)
  Takumi Ueda, Yuichi Minato, Shiho Suzuki, Tomoaki Hara, Yutaka Kofuku, Go Kasuya, Yuichiro Fujiwara, Shunsuke Igarashi, Ei-ichiro Suzuki, Osamu Nureki, Motoyuki Hattori, Takumi Ueda, Ichio Shimada
- Organizer
  58th Experimental Nuclear Magnetic Resonance Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01531
[Presentation] Functional dynamics of membrane proteins revealed by NMR2017
- Author(s)
  上田　卓見、嶋田　一夫
- Organizer
  第55回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08191
[Presentation] Conductance of P2X4 receptor is determined by conformational equilibrium in the transmembrane region2017
- Author(s)
  Takumi Ueda, Yuichi Minato, Shiho Suzuki, Tomoaki Hara, Yutaka Kofuku, Go Kasuya, Yuichiro Fujiwara, Shunsuke Igarashi, Ei-ichiro Suzuki, Osamu Nureki, Motoyuki Hattori, Ichio Shimada
- Organizer
  58th Experimental Nuclear Magnetic Resonance Conference
- Place of Presentation
  Asilomar Conference Grounds, Pacific Grove, CA, USA
- Year and Date
  2017-03-26
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08191
[Presentation] 動的構造に着目したGタンパク質共役型受容体の機能解明2017
- Author(s)
  幸福裕、上田卓見、嶋田一夫
- Organizer
  第61回日本薬学会関東支部大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H06097
[Presentation] Functional dynamics of membrane proteins revealed by NMR2017
- Author(s)
  上田　卓見、嶋田　一夫
- Organizer
  第55回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01531
[Presentation] Functional dynamics of membrane proteins revealed by NMR2017
- Author(s)
  上田卓見、嶋田一夫
- Organizer
  蛋白質科学会
- Invited
- Data Source
  KAKENHI-PROJECT-17H06097
[Presentation] 安定同位体標識法の応用による、蛋白質の動的構造の解明2017
- Author(s)
  上田　卓見、嶋田　一夫
- Organizer
  第56回NMR討論会
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01531
[Presentation] リガンドとの相互作用に伴う膜蛋白質の動的立体構造変化2015
- Author(s)
  上田卓見、幸福裕、嶋田一夫
- Organizer
  第53回生物物理学会
- Place of Presentation
  金沢大学角間キャンパス、金沢
- Year and Date
  2015-09-14
- Invited
- Data Source
  KAKENHI-PUBLICLY-26120506
[Presentation] リガンドとの相互作用に伴う膜蛋白質の動的立体構造変化2015
- Author(s)
  上田卓見、幸福裕、嶋田一夫
- Organizer
  第53回生物物理学会
- Place of Presentation
  金沢大学角間キャンパス、金沢
- Year and Date
  2015-09-14
- Invited
- Data Source
  KAKENHI-PROJECT-25460033
[Presentation] 多次元NMRスペクトル再構成法の開発とケモカイン-ケモカイン受容体複合体の転移交差飽和実験への応用2015
- Author(s)
  上田卓見, 吉浦知絵, 幸福裕, 松本昌彦, 奥出順也, 近藤啓太, 白石勇太郎, 嶋田一夫
- Organizer
  第54回NMR討論会
- Place of Presentation
  千葉工業大学津田沼キャンパス、千葉
- Year and Date
  2015-11-08
- Data Source
  KAKENHI-PROJECT-25460033
[Presentation] 多次元NMRスペクトル再構成法の開発とケモカイン-ケモカイン受容体複合体の転移交差飽和実験への応用2015
- Author(s)
  上田卓見, 吉浦知絵, 幸福裕, 松本昌彦, 奥出順也, 近藤啓太, 白石勇太郎, 嶋田一夫
- Organizer
  第54回NMR討論会
- Place of Presentation
  千葉工業大学津田沼キャンパス、千葉
- Year and Date
  2015-11-08
- Data Source
  KAKENHI-PUBLICLY-26120506
[Presentation] 二次元NMRインターフェログラム再構成法の開発およびCCR5のMIP-1α結合様式の解明への応用2014
- Author(s)
  上田卓見、吉浦知絵、松本昌彦、幸福裕、奥出順也、近藤啓太、白石勇太郎、嶋田一夫
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本県熊本市
- Data Source
  KAKENHI-PLANNED-21121002
[Presentation] NMRによる、限定されたデータからのGPCRの動的構造情報の抽出2014
- Author(s)
  上田卓見
- Organizer
  第14回蛋白質科学会年会
- Place of Presentation
  ワークピア横浜、横浜
- Year and Date
  2014-06-25
- Invited
- Data Source
  KAKENHI-PUBLICLY-26120506
[Presentation] NMRを用いた過渡的蛋白質－蛋白質複合体の結合様式の解明2014
- Author(s)
  上田卓見
- Organizer
  大阪大学蛋白質研究所セミナー　"結晶構造を併用したハイブリッド構造研究の最前線"
- Place of Presentation
  大阪府・大阪大学蛋白質研究所
- Invited
- Data Source
  KAKENHI-PROJECT-25460033
[Presentation] 二次点NMRインターフェログラム再構成法の開発およびCCR5のMIP-1α結合様式の解明への応用2014
- Author(s)
  上田卓見、吉浦知絵、松本昌彦、幸福裕、奥出順也、近藤啓太、白石勇太郎、嶋田一夫
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本県・熊本市総合体育館
- Data Source
  KAKENHI-PROJECT-25460033
[Presentation] β2-アドレナリン受容体のシグナル制御機構の解明2014
- Author(s)
  幸福　裕，上田　卓見，奥出　順也，白石　勇太郎，近藤　啓太，前田　正洋，
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本県熊本市
- Data Source
  KAKENHI-PLANNED-21121002
[Presentation] 脂質二重膜中の脂質による GPCR の活性制御機構の解明2014
- Author(s)
  水村　拓也、近藤　啓太、幸福　裕、上田　卓見、嶋田　一夫
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本県熊本市
- Data Source
  KAKENHI-PLANNED-21121002
[Presentation] NMR 法による脂質二重膜中における P2X4受容体の動的構造平衡の解明2014
- Author(s)
  鈴木　志歩，湊　雄一，幸福　裕，上田　卓見，服部　素之，濡木　理，嶋田　一夫
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本県熊本市
- Data Source
  KAKENHI-PLANNED-21121002
[Presentation] NMR 法による P2X4 受容体の開閉制御機構の解明2014
- Author(s)
  湊　雄一、鈴木　志歩，幸福　裕，上田　卓見，服部　素之，濡木　理，嶋田　一夫
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本県熊本市
- Data Source
  KAKENHI-PLANNED-21121002
[Presentation] β2 アドレナリン受容体のリン酸化によるシグナル制御機構の解明2014
- Author(s)
  白石　勇太郎，幸福　裕，上田　卓見，嶋田　一夫
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本県熊本市
- Data Source
  KAKENHI-PLANNED-21121002
[Presentation] Elucidation of the transient interaction between ubiquitin and yeast ubiquitin hydrolase by NMR2013
- Author(s)
  小笠　広起、上田　卓見、松本　昌彦、嶋田　一夫
- Organizer
  Nagoya Symposium - Frontiers in Structural Physiology
- Place of Presentation
  愛知県名古屋市
- Data Source
  KAKENHI-PLANNED-21121002
[Presentation] Alternate Signal Transduction Mechanism of CheA and CheY revealed by NMR2013
- Author(s)
  湊　雄一、上田　卓見、町山　麻子、岩井　秀夫、嶋田　一夫
- Organizer
  Nagoya Symposium - Frontiers in Structural Physiology
- Place of Presentation
  愛知県名古屋市
- Data Source
  KAKENHI-PLANNED-21121002
[Presentation] イオンチャネルの機能に関連した動的構造2013
- Author(s)
  今井駿輔、○大澤匡範、三田建一郎、豊永翔、町山麻子、上田卓見、竹内恒、老木成稔、嶋田一夫
- Organizer
  第35回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  東京都文京区
- Invited
- Data Source
  KAKENHI-PLANNED-21121002
[Presentation] NMRによるGタンパク質共役型受容体の機能解明2013
- Author(s)
  上田　卓見
- Organizer
  第4回神経科学と構造生物学の融合研究会
- Place of Presentation
  愛知県・岡崎コンファレンスセンター
- Invited
- Data Source
  KAKENHI-PROJECT-25460033
[Presentation] Efficacy of the b2-adrenergic receptor is determined by conformational2013
- Author(s)
  幸福裕、上田卓見、奥出順也、白石勇太郎、近藤啓太、前田正洋、辻下英樹、嶋田一夫
- Organizer
  Nagoya Symposium - Frontiers in Structural Physiology
- Place of Presentation
  愛知県名古屋市
- Data Source
  KAKENHI-PLANNED-21121002
[Presentation] Elucidation of the mechanism of analgesic tolerance by chronic administration of morphine2012
- Author(s)
  奥出順也*, 吉浦知絵, 白石勇太郎*, 幸福裕, 上田卓見, 嶋田一夫
- Organizer
  第132回日本薬学会年会日本薬学会
- Place of Presentation
  北海道大学(札幌)
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PLANNED-21121002
[Presentation] Gタンパク質共役型受容体の動的平衡の制御機構の解明2012
- Author(s)
  近藤　啓太、幸福　裕、上田　卓見、嶋田　一夫
- Organizer
  第85回日本生化学会年会
- Place of Presentation
  福岡県福岡市
- Data Source
  KAKENHI-PLANNED-21121002
[Presentation] Development of interferogram extrapolation method for NMR experiments that requires accurate peakheight2012
- Author(s)
  Takumi Ueda, Masahiko Matsumoto, Ichio Shimada
- Organizer
  ISNMR2011
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790042
[Presentation] Structural Elucidation of the Alternate Signal Transduction Mechanism of CheA and CheY2012
- Author(s)
  湊　雄一、上田　卓見、町山　麻子、岩井　秀夫、嶋田　一夫
- Organizer
  25th ICMRBS
- Place of Presentation
  リヨン、フランス
- Data Source
  KAKENHI-PLANNED-21121002
[Presentation] Structural Elucidation of the AlternateSignal Transduction Mechanism of CheA2012
- Author(s)
  Yuichi Minato, Takumi Ueda, AsakoMachiyama, Hideo Iwai, Ichio Shimada,
- Organizer
  International Conference on MagneticResonance in Biological Systems
- Place of Presentation
  リヨン(フランス)
- Data Source
  KAKENHI-PROJECT-23790042
[Presentation] Elucidation of regulatory mechanism for arrestin activation by G-protein coupled receptor (ポスター)2012
- Author(s)
  白石勇太郎*, 幸福裕, 奥出順也*, 吉浦知絵, 阿内康平*, 上田卓見, 嶋田一夫
- Organizer
  第132回日本薬学会年会日本薬学会
- Place of Presentation
  北海道大学(札幌)
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PLANNED-21121002
[Presentation] Protein-protein docking method utilizing the intermolecular 1H-1H distance restraints obtained by the quantitative cross-saturation method2012
- Author(s)
  松本　昌彦、上田　真也、上田　卓見、嶋田　一夫
- Organizer
  25th ICMRBS
- Place of Presentation
  リヨン、フランス
- Data Source
  KAKENHI-PLANNED-21121002
[Presentation] Elucidation of the transient interaction between ubiquitin and yeast ubiquitin hydrolase2012
- Author(s)
  小笠　広起、上田　卓見、松本　昌彦、嶋田　一夫
- Organizer
  25th ICMRBS
- Place of Presentation
  リヨン、フランス
- Data Source
  KAKENHI-PLANNED-21121002
[Presentation] Development of interferogram extrapolation method for NMR experiments that requires accurate peak height2011
- Author(s)
  Takumi Ueda, Masahiko Matsumoto, Ichio Shimada
- Organizer
  ISNMR2011
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PUBLICLY-23121511
[Presentation] Development of interferogram extrapolation method for NMR experiments that requires accurate peak height2011
- Author(s)
  Takumi Ueda, Masahiko Matsumoto, Ichio Shimada
- Organizer
  ISNMR2011
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23790042
[Presentation] NMR法によるactinとactin結合タンパク質との相互作用解析法の開発2010
- Author(s)
  黄淑嫻、梅本良、上田太郎、西田紀貴、嶋田一夫
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド,兵庫県
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PLANNED-21121002
[Presentation] 細菌の走化性における膜外から膜内へのシグナル伝達機構の構造生物学的解明2009
- Author(s)
  港雄一、町山麻子、上田卓見, 嶋田一夫
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜)
- Data Source
  KAKENHI-PROJECT-20790029
[Presentation] 膜貫通受容体 Chemoreceptor から細胞内キナーゼCheAへのシグナル伝達機構の構造生物学的解明2009
- Author(s)
  町山麻子、湊雄一、上田卓見、嶋田一夫
- Organizer
  第82会日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(神戸)
- Data Source
  KAKENHI-PROJECT-20790029
[Presentation] TCS法を用いたCOPI小胞形成機構の解明2009
- Author(s)
  富永紗衣、幸福裕、上田卓見、嶋田一夫
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜)
- Data Source
  KAKENHI-PROJECT-20790029
[Presentation] CCR5―リガンド間相互作用に関する構造生物学的解析2009
- Author(s)
  吉浦知絵、幸福裕、上田卓見、寺島裕也、松島綱治、嶋田一夫
- Organizer
  第48回NMR討論会
- Place of Presentation
  九州大学馬出病院キャンパス医学部百年講堂(福岡)
- Data Source
  KAKENHI-PROJECT-20790029
[Presentation] NMR法を用いたケモカインSDF-1/CXCL12とケモカイン受容体CXCR4との相互作用様式の解明2009
- Author(s)
  幸福裕、吉浦知絵、上田卓見、寺沢宏明、平井隆寛、富永紗衣、廣瀬雅子、前田宜丈、高橋栄夫、寺島裕也、松島綱治、嶋田一夫
- Organizer
  第82会日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(神戸)
- Data Source
  KAKENHI-PROJECT-20790029
[Presentation] Structural elucidation of the recognition mechanism of photo system I and ferredoxin by transferred cross-saturation method2008
- Author(s)
  Naoko Nomoto, Takumi Ueda, Ichio Shimada
- Organizer
  XXIII^<rd> ICMRBS
- Place of Presentation
  San Diego, California, USA
- Data Source
  KAKENHI-PROJECT-20790029
[Presentation] NMRによるGタンパク質共役型受容体の機能解明
- Author(s)
  上田　卓見
- Organizer
  第4回神経科学と構造生物学の融合研究会
- Place of Presentation
  愛知県・岡崎コンファレンスセンター
- Year and Date
  2013-11-19 – 2013-11-20
- Invited
- Data Source
  KAKENHI-PUBLICLY-25121708
[Presentation] NMRによる、限定されたデータからのGPCRの動的構造情報の抽出
- Author(s)
  上田　卓見
- Organizer
  第14回蛋白質科学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-06-25 – 2014-06-27
- Invited
- Data Source
  KAKENHI-PROJECT-25460033
[Presentation] NMRを用いた過渡的蛋白質－蛋白質複合体の結合様式の解明
- Author(s)
  上田　卓見
- Organizer
  大阪大学蛋白質研究所セミナー "結晶構造を併用したハイブリッド構造研究の最前線"
- Place of Presentation
  大阪府・大阪大学蛋白質研究所
- Year and Date
  2014-02-07 – 2014-02-08
- Invited
- Data Source
  KAKENHI-PUBLICLY-25121708
[Presentation] 二次元NMRインターフェログラム再構成法の開発およびCCR5のMIP-1a結合様式の解明への応用
- Author(s)
  上田卓見、吉浦知絵、松本昌彦、幸福裕、奥出順也、近藤啓太、白石勇太郎、嶋田一夫
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本県・熊本市総合体育館
- Year and Date
  2014-03-27 – 2014-03-30
- Data Source
  KAKENHI-PUBLICLY-25121708
[Presentation] NMRによる、限定されたデータからのGPCRの動的構造情報の抽出
- Author(s)
  上田　卓見
- Organizer
  第14回蛋白質科学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-06-25 – 2014-06-27
- Invited
- Data Source
  KAKENHI-PUBLICLY-25121708

1. SHIMADA Ichio (70196476)

# of Collaborated Projects: 4 results

# of Collaborated Products: 53 results
2. KAINOSHO Masatsune (20137029)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. NISHIDA Noritaka (50456183)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. JEE Jungoo (50381554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. OSAWA Masanori (60361606)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
6. 竹内恒 (20581284)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 生長幸之助 (00583999)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. HAYASAKA Haruko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 幸福裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
10. 徳永裕二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 今井駿輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 住本英樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ueda Takumi 上田 卓見

UEDA Takumi 上田 卓見

Research Projects

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Co-Researchers

Protein Backbone Cyclization and Application to Precise Solution Structure Analysis

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GPCRの活性化状態が薬物の親和性を規定するメカニズムの解明Principal Investigator

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溶液NMR法による効率的な特殊ペプチドの動的立体構造解析法の開発Principal Investigator

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薬物とGPCRの弱い相互作用が滞在時間に応じて生体応答を制御する機構の解明Principal Investigator

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Clarification of GPCR signaling regulation mechanism by NMRPrincipal Investigator

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動的構造平衡情報に基づく数理解析によるGPCRのシグナル制御機構の解明Principal Investigator

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核磁気共鳴法による分子夾雑系膜環境におけるG蛋白質共役型受容体の機能解明Principal Investigator

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In situ functional analyses of membrane proteins by NMR

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Development of methods for studying conformational dynamics of ubiquitin-ubiquitin binding protein complexPrincipal Investigator

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高次元NMRデータ解析法の開発およびGPCRの機能解明への応用Principal Investigator

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スパース性を使った新規多次元NMRスペクトル再構成法の開発とGPCR研究への応用Principal Investigator

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医学上重要なGPCRのシグナル制御機構の構造生物学的解明Principal Investigator

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Structural elucidation of the mechanism underlying biased signaling of GPCRsPrincipal Investigator

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Ueda Takumi 上田卓見

UEDA Takumi 上田卓見