Uchibori Ryosuke 内堀亮介

… Alternative Names

内堀亮介ウチボリリョウスケ

UCHIBORI Ryosuke 内堀亮介

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Researcher Number	20458285
Other IDs
Affiliation (Current)	2025: 自治医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2021: 自治医科大学, 医学部, 講師 2019: 自治医科大学, 医学部, 講師 2016 – 2017: 自治医科大学, 医学部, 講師 2011 – 2014: 自治医科大学, 医学部, 助教 2009 – 2010: 自治医科大学, 医学部, 研究員
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Tumor therapeutics / Tumor immunology Except Principal Investigator Hematology
Keywords	Principal Investigator キメラ抗原受容体 / 造血器腫瘍 / 多発性骨髄腫 / CAR / エリスロポエチン / CAR-T療法 / B細胞性リンパ腫 / SRG / 選択的制御遺伝子 / がん免疫療法 … More / 養子免疫療法 / 遺伝子治療 / 細胞療法 / 養子免疫遺伝子細胞治療 / BCMA / CD269 / 分子スイッチ / シグナル伝達 / がん / 細胞・遺伝子治療 … More Except Principal Investigator 遺伝子治療 / 血液腫瘍学 / 造血器腫瘍 / Tリンパ球 / キメラ抗原受容体 / 細胞療法 / 免疫療法 / ゲノム / 移植再生医療 / 癌 / 間葉系幹細胞 Less

Development of selective regulatory system for proliferation and persistence of CAR-T cellsPrincipal Investigator
- Principal Investigator
  
  Uchibori Ryosuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Jichi Medical University
Development of CD269-CAR T cells for the adoptive immunotherapy of multiple myeloma.Principal Investigator
- Principal Investigator
  
  Uchibori Ryosuke
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Jichi Medical University
Development of gene therapy for refractory non-Hodgkin lymphoma using T-cells expressing a chimeric antigen receptor
- Principal Investigator
  
  OZAWA keiya
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
Development of switch promoters driven by activation signals from the chimeric antigen receptors.Principal Investigator
- Principal Investigator
  
  UCHIBORI Ryosuke
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor immunology
- Research Institution
  Jichi Medical University
Development of gene therapy using bone-marrow-derived mesenchymal stem cells
- Principal Investigator
  
  OZAWA Keiya
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University

All 2019 2018 2017 2016 2015 2014 2013 2011 2010 2009 Other

All Journal Article Presentation

[Journal Article] CAR-T cell（キメラ抗原受容体発現Ｔ細胞）Therapy2018
- Author(s)
  内堀亮介, 小澤敬也
- Journal Title
  
  医薬ジャーナル
  
  Volume: 54 Pages: 79-85
- Data Source
  KAKENHI-PROJECT-16K18459
[Journal Article] 多発性骨髄腫に対するキメラ抗原受容体T 細胞療法の可能性2017
- Author(s)
  内堀亮介
- Journal Title
  
  血液内科
  
  Volume: 74 Pages: 392-397
- NAID
  40021144514
- Data Source
  KAKENHI-PROJECT-16K18459
[Journal Article] 多発性骨髄腫に対するCAR-T細胞療法の開発研究2017
- Author(s)
  内堀亮介
- Journal Title
  
  血液フロンティア
  
  Volume: 27 Pages: 49-56
- Data Source
  KAKENHI-PROJECT-16K18459
[Journal Article] The Tol2 transposon system mediates the genetic engineering of T-cells with CD19-specific chimeric antigen receptors for B-cell malignancies2015
- Author(s)
  Tsukahara, T., Iwase, N., Kawakami, K., Iwasaki, M., Yamamoto, C., Ohmine, K., Uchibori, R., Teruya, T., Ido, H., Saga, Y., Urabe, M., Mizukami, H., Kume, A., Nakamura, M., Brentjens, R., and Ozawa, K.
- Journal Title
  
  Gene Therapy
  
  Volume: 22 Issue: 2 Pages: 209-215
- DOI
  10.1038/gt.2014.104
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23241063, KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-25430155, KAKENHI-PROJECT-26430168
[Journal Article] Novel anti-tumor mechanism of galanin receptor type 2 in head and neck squamous cell carcinoma cells2014
- Author(s)
  Uehara T, Kanazawa T, Mizukami H, Uchibori R, Tsukahara T, Urabe M, Kume A, Misawa K, Carey T, Suzuki M, Ichimura K, Ozawa K
- Journal Title
  
  Cancer Science
  
  Volume: 105 Issue: 1 Pages: 72-80
- DOI
  10.1111/cas.12315
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591548, KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-24592594, KAKENHI-PROJECT-25430155, KAKENHI-PROJECT-25461460
[Journal Article] Cancer gene therapy using mesenchymal stem cells.2014
- Author(s)
  Uchibori R, Tsukahara T, Ohmine K, Ozawa K.
- Journal Title
  
  Int J Hematol.
  
  Volume: 99 Issue: 4 Pages: 377-82
- DOI
  10.1007/s12185-014-1537-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-25430155, KAKENHI-PROJECT-26430168
[Journal Article] IL-21 is not necessary for anti-lymphoma effects of T cells expressing second-generation CD19-specific chimeric antigen receptors in a xenograft mouse model.2014
- Author(s)
  Yamamoto C, Tsukahara T, Omine K, Teruya T, Ido H, Uchibori R, Urabe M, Mizukami H, Kume A, Nakamura M, Ozawa K.
- Journal Title
  
  Jichi Medical University Journal
  
  Volume: 36 Pages: 23-31
- NAID
  120006408261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390247
[Journal Article] NF-κB activity regulates mesenchymal stem cell accumulation at tumor sites.2013
- Author(s)
  Uchibori R, Tsukahara T, Mizuguchi H, Saga Y, Urabe M, Mizukami H, Kume A, Ozawa K
- Journal Title
  
  Cancer Research
  
  Volume: 73 Issue: 1 Pages: 364-372
- DOI
  10.1158/0008-5472.can-12-0088
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591548, KAKENHI-PROJECT-23659493, KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-24700995, KAKENHI-PROJECT-25430155
[Journal Article] CD19 target-engineered T-cells accumulate at tumor lesions in human B-cell lymphoma xenograft mouse models2013
- Author(s)
  Tsukahara T, Ohmine K, Yamamoto C, Uchibori R, Ido H, Teruya T, Urabe M, Mizukami H, Kume A, Nakamura M, Mineno J, Takesako K, Riviere I, Sadelain M, Brentjens R, Ozawa K
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 438 Issue: 1 Pages: 84-89
- DOI
  10.1016/j.bbrc.2013.07.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591548, KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-24700995, KAKENHI-PROJECT-25430155
[Journal Article] Establishment and characterization of transplantable, luminescence labeled rat renal cell carcinoma cell lines2010
- Author(s)
  Kobayashi M, Murakami T, Uchibori R, Chun NA, Kobayashi E, Morita T, Ozawa K.
- Journal Title
  
  J Urol
  
  Volume: 183巻 Pages: 2029-2035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390296
[Journal Article] 間葉系幹細胞を用いたがん標的化療法2010
- Author(s)
  Uchibori, R.
- Journal Title
  
  臨床血液
  
  Volume: 51 Pages: 1641-6
- NAID
  10027751339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390296
[Journal Article] Scalable purification of adeno-associated virus serotype 1(AAV1) and AAV8 vectors, using dual ion-exchange adsorptive membranes2009
- Author(s)
  Okada T, Nonaka-Sarukawa M, Uchibori R, Kinoshita K, Hayashita-Kinoh H, Nitahara-Kasahara Y, Takeda S, and Ozawa K
- Journal Title
  
  Hum. Gene Ther
  
  Volume: 20巻 Pages: 1013-1021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390296
[Journal Article] Retroviral vector-producing mesenchymal stem cells for targeted suicide cancer gene therapy2009
- Author(s)
  Uchibori R, Okada T, Ito T, Mizukami H, Kume A and Ozawa, K
- Journal Title
  
  J. Gene Med
  
  Volume: 11巻 Pages: 373-381
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390296
[Journal Article] Retroviral vector-producing mesenchymal stem cells for targeted suicide cancer gene therapy.2009
- Author(s)
  Uchibori, R.
- Journal Title
  
  J.Gene Med. 46
  
  Pages: 373-381
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390296
[Presentation] Analysis of RetroNectin-Mediated T-Cell Activation on Expansion and Phenotype of Chimeric Antigen Receptor T Cells2019
- Author(s)
  Ryosuke Uchibori、 Ken Ohmine、Junichi Mineno、Keiya Ozawa
- Organizer
  The 10th Meeting of ACTO
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07714
[Presentation] CAR-T therapy for multiple myeloma.2017
- Author(s)
  Uchibori R.
- Organizer
  The 23rd Annual Meeting of the Japan Society of Gene Therapy.
- Invited
- Data Source
  KAKENHI-PROJECT-16K18459
[Presentation] CD269（BCMA）を標的とした多発性骨髄腫に対するCAR-T療法2017
- Author(s)
  内堀亮介
- Organizer
  第23回血液科学セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16K18459
[Presentation] AR-T療法の基礎2017
- Author(s)
  内堀亮介
- Organizer
  第32回悪性リンパ腫治療研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16K18459
[Presentation] CD269-CAR-T therapy for bone lesions in myeloma model mice.2017
- Author(s)
  Uchibori R, Ohmine K, Mineno J, Takesako K, and Ozawa K.
- Organizer
  The 8th JSH International Symposium.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18459
[Presentation] Effect of CAR-T therapy on bone lesions in an orthotopic multiple myeloma mouse model.2017
- Author(s)
  Uchibori R, Ohmine K, Sehara Y, Urabe M, Mizukami H, Mineno J, Takesako K, and Ozawa K.
- Organizer
  20th Annual Meeting of the American Society of Gene & Cell Therapy.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18459
[Presentation] CD269-targeted CAR-modified T cells showed promising therapeutic efficacy in an orthotopic mouse model of multiple myeloma.2016
- Author(s)
  Ryosuke Uchibori, Takeshi Teruya, Ken Ohmine, Masashi Urabe, Yasushi Saga, Hiroaki Mizukami, Junichi Mineno, and Keiya Ozawa.
- Organizer
  第22回日本遺伝子細胞治療学会
- Place of Presentation
  虎ノ門ヒルズフォーラム（東京都、港区）
- Year and Date
  2016-07-28
- Data Source
  KAKENHI-PROJECT-16K18459
[Presentation] CD269 (BCMA)-specific CAR-expressing T cells dramatically eradicate myeloma cells from bone marrow of an orthotopic multiple myeloma mouse model.2016
- Author(s)
  Ryosuke Uchibori, Takeshi Teruya, Ken Ohmine, Masashi Urabe, Yasushi Saga, Hiroaki Mizukami, Junichi Mineno, Kazuto Takesako, and Keiya Ozawa.
- Organizer
  The 19th Annual Meeting of the American Society of Gene & Cell Therapy
- Place of Presentation
  Washington, D.C., USA.
- Year and Date
  2016-05-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18459
[Presentation] Therapeutic efficacy of CD269-targeted CAR-modified T cells in an orthotopic mouse model of multiple myeloma.2016
- Author(s)
  Ryosuke Uchibori, Ken Ohmine, Masashi Urabe, Hiroaki Mizukami, Junichi Mineno, and Keiya Ozawa.
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PROJECT-16K18459
[Presentation] Assessment of the efficacy and safety of CD269-specific CAR-expressing T cells using an orthotopic multiple myeloma mouse model.2016
- Author(s)
  Ryosuke Uchibori, Takeshi Teruya, Ken Ohmine, Junichi Mineno, Kazuto Takesako, and Keiya Ozawa.
- Organizer
  The 7th JSH International Symposium
- Place of Presentation
  淡路夢舞台（兵庫県、淡路市）
- Year and Date
  2016-05-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18459
[Presentation] Efficacy of adoptive immunotherapy with 269-CAR T cells in an orthotopic NOG mouse-human tumor xenograft model.2016
- Author(s)
  内堀亮介、照屋武志、大嶺謙、峰野純一、小澤敬也
- Organizer
  第8回血液疾患免疫療法学会
- Place of Presentation
  北海道大学医学部学友会館（北海道、札幌市）
- Year and Date
  2016-09-03
- Data Source
  KAKENHI-PROJECT-16K18459
[Presentation] Therapeutic efficacy of CD269-specific CAR T cells in an orthotopic mouse model of multiple myeloma.2016
- Author(s)
  Ryosuke Uchibori, Takeshi Teruya, Ken Ohmine, Masashi Urabe, Yasushi Saga, Hiroaki Mizukami, Junichi Mineno, and Keiya Ozawa.
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2016-10-14
- Data Source
  KAKENHI-PROJECT-16K18459
[Presentation] キメラ抗原受容体からの抗原刺激特異的な遺伝子発現誘導系の開発.2014
- Author(s)
  内堀亮介, 二宮空暢, 照屋武志, 塚原智典, 大嶺謙, 峰野純一, 竹迫一任, 小澤敬也.
- Organizer
  第6回血液疾患免疫療法研究会
- Place of Presentation
  京都
- Year and Date
  2014-09-06
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] Generation of T-cells expressing a CD19-specific CAR by the Tol2 transposon system.2014
- Author(s)
  Tsukahara T, Ohmine K, Uchibori R, Urabe M, Mizukami H, Kume A, Nakamura M, Ozawa K.
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] The NFAT response elements in the IL-2 gene promoter permit visualization and quantification of activation status in CAR-expressing PBMCs.2014
- Author(s)
  Uchibori R, Ninomiya S, Tsukahara T, Ido H, Teruya T, Ohmine K, Urabe M, Mizukami H, Kume A, Riviere I, Sadelain M, Brentjens RJ, Mineno J, Ozawa K.
- Organizer
  第20回日本遺伝子治療学会
- Place of Presentation
  東京
- Year and Date
  2014-08-08
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] Activation signals from CAR permit NFAT-controlled inducible expression of transgenes in PBMCs.2014
- Author(s)
  Uchibori R, Ninomiya S, Tsukahara T, Ido H, Teruya T, Ohmine K, Urabe M, Mizukami H, Kume A, Riviere I, Sadelain M, Brentjens RJ, Mineno J, Ozawa K.
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-11-02
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] Tol2 transposon-based gene transfer of CD19-specific chimeric antigen receptors into human T-cells.2014
- Author(s)
  Tsukahara T, Iwase N, Yamamoto C, Ohmine K, Uchibori R, Teruya T, Ido H, Urabe M, Mizukami H, Kume A, Nakamura M, Brentjens R, Kawakami K and Ozawa K.
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-11-02
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] Activation signals from chimeric antigen receptors permit NFAT-controlled inducible expression of transgene in PBMCs.2014
- Author(s)
  Uchibori R, Ninomiya S, Tsukahara T, Ido H, Teruya T, Ohmine K, Urabe M, Mizukami H, Kume A, Mineno J, Ozawa K.
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] Analysis of function and response specificity of a switch promoter driven by activation signals from a CD19-targeted chimeric antigen receptor.2014
- Author(s)
  Uchibori R, Takeshi T, Tsukahara T, Ohmine K, Riviere I, Brentjens RJ, Sadelain M, Mineno J, Takesako K, Ozawa K.
- Organizer
  The 5th Meeting of Asian Cellular Therapy Organization.
- Place of Presentation
  大阪
- Year and Date
  2014-11-11
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] Development of switch promoters that is activated to induce exogenous gene expression upon the recognition of CD19 by chimeric antigen receptors.2014
- Author(s)
  Uchibori R, Ninomiya S, Tsukahara T, Ido H, Teruya T, Ohmine K, Urabe M, Mizukami H, Kume A, Riviere I, Sadelain M, Brentjens RJ, Mineno J, Ozawa K.
- Organizer
  17th Annual Meeting of the American Society of Gene & Cell Therapy.
- Place of Presentation
  Washington, D.C.
- Year and Date
  2014-05-22
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] Tol2 transposon-mediated gene transfer of CD19-CAR to primary human T-cells for the treatment of B-cell malignancies.2014
- Author(s)
  Tsukahara T, Iwase N, Yamamoto C, Ohmine K, Uchibori R, Takeshi T, Urabe M, Mizukami H, Kume A, Nakamura M, Brentjens R J, Kawakami K, Ozawa K.
- Organizer
  第20回日本遺伝子治療学会
- Place of Presentation
  東京
- Year and Date
  2014-08-08
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] Development of switch promoters driven by activation signals from the chimeric antigen receptors2013
- Author(s)
  Uchibori R, Ninomiya S, Tsukahara T, Ohmine K, Urabe M, Mizukami H, Kume A, Mineno J, Ozawa K
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2013-10-12
- Data Source
  KAKENHI-PROJECT-24700995
[Presentation] DEVELOPMENT OF SIN RETROVIRAL VECTORS EQUIPPED WITH SWITCH PROMOTERS DRIVEN BY ACTIVATION SIGNALS FROM THE CHIMERIC ANTIGEN RECEPTORS2013
- Author(s)
  Uchibori R, Ninomiya S, Tsukahara T, Ido H, Teruya T, Ohmine K, Urabe M, Mizukami H, Kume A, Riviere I, Sadelain M, Brentjens RJ, Mineno J, Ozawa K
- Organizer
  第18回日本遺伝子治療学会
- Place of Presentation
  岡山
- Year and Date
  2013-07-06
- Data Source
  KAKENHI-PROJECT-24700995
[Presentation] Development of switch promoters that would respond to activation signals from the chimeric antigen receptors2013
- Author(s)
  Uchibori R, Ninomiya S, Tsukahara T, Ido H, Teruya T, Ohmine K, Urabe M, Mizukami H, Kume A, Riviere I, Sadelain M, Brentjens RJ, Mineno J, Ozawa K
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2013-10-05
- Data Source
  KAKENHI-PROJECT-24700995
[Presentation] Synergistic effect on the tumor-killing activity of soluble TRAIL-expressing MSCs2011
- Author(s)
  Uchibori R
- Organizer
  第70回に本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-21390296
[Presentation] Enhancement of Tumor-Killing Activity of TRAIL-Expressing MSCs by Using Trichostatin A2011
- Author(s)
  Uchibori R
- Organizer
  The 14th Annual Meeting of the American Society of Gene and Cell Therapy
- Place of Presentation
  The Washington State Convention Center(Seattle)
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-21390296
[Presentation] Synergistic effect on the tumor-killing activity of soluble TRAIL-expressing MSCs2011
- Author(s)
  Uchibori, R.
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-21390296
[Presentation] Trichostatin A sensitize apoptosis induced by soluble TRAIL-expressing MSCs2011
- Author(s)
  Uchibori, R.
- Organizer
  The 17^<th> Annual Meeting of the Japan Society of Gene Therapy
- Place of Presentation
  九州大学医学部百年講堂(福岡)
- Year and Date
  2011-07-16
- Data Source
  KAKENHI-PROJECT-21390296
[Presentation] Trichostatin A sensitize apoptosis induced by soluble TRAIL-expressing MSCs2011
- Author(s)
  Uchibori R
- Organizer
  The 17th Annual Meeting of the Japan Society of Gene Therapy
- Place of Presentation
  九州大学医学部百年講堂(福岡)
- Year and Date
  2011-07-16
- Data Source
  KAKENHI-PROJECT-21390296
[Presentation] Enhancement of Tumor-Killing Activity of TRAIL-Expressing MSCs by Using Trichostatin A2011
- Author(s)
  Uchibori, R.
- Organizer
  The 14^<th> Annual Meeting of the American Society of Gene and Cell Therapy
- Place of Presentation
  The Washington State Convention Center (Seattle)
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-21390296
[Presentation] The effect of DMXAA (TNF-α inducer) on MSC accumulation at tumor sites.2010
- Author(s)
  Uchibori, R.
- Organizer
  第16回日本癌学会総会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21390296
[Presentation] NF-κB activity regulates MSC accumulation at tumor sites2010
- Author(s)
  Uchibori R
- Organizer
  The 13th Annual Meeting of the American Society of Gene Therapy
- Place of Presentation
  Marriott Wardman Park Hotel(Washington, D. C.)
- Year and Date
  2010-05-20
- Data Source
  KAKENHI-PROJECT-21390296
[Presentation] Mesenchymal stem cells as a cellular vehicle for cancer-targeted gene therapy2010
- Author(s)
  Uchibori R
- Organizer
  The 16th Annual Meeting of the Japan Society of Gene Therapy
- Place of Presentation
  栃木県総合文化センター(宇都宮)
- Year and Date
  2010-07-02
- Data Source
  KAKENHI-PROJECT-21390296
[Presentation] The effect of DMXAA(TNF-α inducer) on MSC accumulation at tumor sites2010
- Author(s)
  Uchibori R
- Organizer
  第16回日本癌学会総会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21390296
[Presentation] NF-κB activity regulates MSC accumulation at tumor sites.2010
- Author(s)
  Uchibori, R.
- Organizer
  The 13^<th>Annual Meeting of the American Society of Gene Therapy
- Place of Presentation
  Marriott Wardman Park Hotel (Washington, D.C.)
- Year and Date
  2010-05-20
- Data Source
  KAKENHI-PROJECT-21390296
[Presentation] Mesenchymal stem cells as a cellular vehicle for cancer-targeted gene therapy.2010
- Author(s)
  Uchibori, R.
- Organizer
  The 16^<th> Annual Meeting of the Japan Society of Gene Therapy
- Place of Presentation
  栃木県総合文化センター(宇都宮)
- Year and Date
  2010-07-02
- Data Source
  KAKENHI-PROJECT-21390296
[Presentation] The effect of DMXAA(56-dimethylxanthenone-4-acetic acid) on MSC accumulation in tumor sites2010
- Author(s)
  Uchibori R
- Organizer
  The 16th Annual Meeting of the Japan Society of Gene Therapy
- Place of Presentation
  栃木県総合文化センター(宇都宮)
- Year and Date
  2010-07-01
- Data Source
  KAKENHI-PROJECT-21390296
[Presentation] The effect of DMXAA (56-dimethylxanthenone-4-acetic acid) on MSC accumulation in tumor sites.2010
- Author(s)
  Uchibori, R.
- Organizer
  The 16^<th> Annual Meeting of the Japan Societyof Gene Therapy
- Place of Presentation
  栃木県総合文化センター(宇都宮)
- Year and Date
  2010-07-01
- Data Source
  KAKENHI-PROJECT-21390296
[Presentation] Roles of inflammatory cytokines in tumor tropism of mesenchimal stromal cells2009
- Author(s)
  Uchibori R
- Organizer
  The 12th Annual Meeting of the American Society of Gene Therapy
- Place of Presentation
  San Diego Convention Center(San Diego)
- Year and Date
  2009-05-28
- Data Source
  KAKENHI-PROJECT-21390296
[Presentation] Cancer-targeted gene therapy using MSCs as a platform2009
- Author(s)
  Uchibori R
- Organizer
  Annual Meeting of the International Society for Cell and Gene Therapy of Cancer
- Place of Presentation
  Ireland
- Year and Date
  2009-09-03
- Data Source
  KAKENHI-PROJECT-21390296
[Presentation] VCAM-1 expression following TNF-alpha stimulation is required for tumor tropism of mesenchymal stem cells2009
- Author(s)
  Uchibori, R.
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21390296
[Presentation] Mesenchymal stem cells(MSCs)as a platform for cancer gene therapy2009
- Author(s)
  Uchibori, R.
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21390296
[Presentation] Mechanism of MSC(Mesenchymal stem/stromal cell) accumulation at tumor sites2009
- Author(s)
  Uchibori R
- Organizer
  The 15th Annual Meeting of the Japan Society of Gene Therapy
- Place of Presentation
  大阪大学コンベンションセンター(大阪)
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-21390296
[Presentation] Rloe of TNF-α in the MSC accumulation at tumor sites.2009
- Author(s)
  Uchibori, R.
- Organizer
  The 7^<th> Stem Cell Research Symposium
- Place of Presentation
  Izumi Garden Gallery(Tokyo)
- Year and Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-21390296
[Presentation] Roles of inflammatory cytokines in tumor tropism of mesenchimal stromal cells.2009
- Author(s)
  Uchibori, R.
- Organizer
  The 12^<th> Annual Meeting of the American Society of Gene Therapy
- Place of Presentation
  San Diego Convention Center(San Diego)
- Year and Date
  2009-05-28
- Data Source
  KAKENHI-PROJECT-21390296
[Presentation] VCAM-1 expression following TNF-alpha stimulation is required, for tumor tropism of mesenchymal stem cells2009
- Author(s)
  Uchibori R
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21390296
[Presentation] Mesenchymal stem cells(MSCs) as a platform for cancer gene therapy2009
- Author(s)
  Uchibori R
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21390296
[Presentation] Cancer-targeted gene therapy using MSCs as a platform.2009
- Author(s)
  Uchibori, R.
- Organizer
  Annual Meeting of the International Society for Cell and Gene Therapy of Cancer
- Place of Presentation
  Ireland
- Year and Date
  2009-09-03
- Data Source
  KAKENHI-PROJECT-21390296
[Presentation] Mechanism of MSC(Mesenchymal stem/stromal cell)accumulation at tumor sites.2009
- Author(s)
  Uchibori, R.
- Organizer
  The 15^<th> Annual Meeting of the Japan Society of Gene Therapy
- Place of Presentation
  大阪大学コンベンションセンター(大阪)
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-21390296
[Presentation] Mechanism of MSC(mesenchymal stem/stromal cell)accumulation at the sites of tumors.2009
- Author(s)
  Uchibori R
- Organizer
  The 14^<th> Congress of the European Hematology Association
- Place of Presentation
  Germany
- Data Source
  KAKENHI-PROJECT-21390296
[Presentation] Mechanism of MSC(mesenchymal stem/stromal cell) accumulation at the sites of tumors2009
- Author(s)
  Uchibori R
- Organizer
  The 14th Congress of the European Hematology Association
- Place of Presentation
  Germany
- Data Source
  KAKENHI-PROJECT-21390296
[Presentation] Development of switch promoters driven by activation signals from the chimeric antigen receptors.
- Author(s)
  Uchibori R, Ninomiya S, Tsukahara T, Ohmine K, Urabe M, Mizukami H, Kume A, Mineno J, Ozawa K.
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24700995
[Presentation] Anti-tumor activity of CD19-specific chimeric antigen receptor-modified T-cells for B cell lymphoma.
- Author(s)
  Tsukahara T, Ohmine K, Uchibori R, Ido H, Urabe M, Mizukami H, Kume A, Nakamura M, Ozawa K.
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] Tumor targeting and anti-tumor activity mediated by T-lymphocytes with an anti-CD19 CAR in human B-cell lymphoma models.
- Author(s)
  Tsukahara T, Ohmine K, Uchibori R, Ido H, Urabe M, Mizukami H, Kume A, Nakamura M, Riviere I, Sadelain M, Brentjens R, Ozawa K.
- Organizer
  第18回日本遺伝子治療学会
- Place of Presentation
  岡山市
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] DEVELOPMENT OF SIN RETROVIRAL VECTORS EQUIPPED WITH SWITCH PROMOTERS DRIVEN BY ACTIVATION SIGNALS FROM THE CHIMERIC ANTIGEN RECEPTORS.
- Author(s)
  Uchibori R, Ninomiya S, Tsukahara T, Ido H, Teruya T, Ohmine K, Urabe M, Mizukami H, Kume A, Riviere I, Sadelain M, Brentjens RJ, Mineno J, Ozawa K.
- Organizer
  第18回日本遺伝子治療学会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-24700995
[Presentation] Development of switch promoters that would respond to activation signals from the chimeric antigen receptors.
- Author(s)
  Uchibori R, Ninomiya S, Tsukahara T, Ido H, Teruya T, Ohmine K, Urabe M, Mizukami H, Kume A, Riviere I, Sadelain M, Brentjens RJ, Mineno J, Ozawa K.
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24700995
[Presentation] Tumor targeting using T-lymphocytes with an anti-CD19 chimeric antigen receptor for B cell lymphoma.
- Author(s)
  Tsukahara T, Ohmine K, Uchibori R, Ido H, Urabe M, Mizukami H, Kume A, Nakamura M, Riviere I, Sadelain M, Brentjens R, Ozawa K.
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] DEVELOPMENT OF SIN RETROVIRAL VECTORS EQUIPPED WITH SWITCH PROMOTERS DRIVEN BY ACTIVATION SIGNALS FROM THE CHIMERIC ANTIGEN RECEPTORS.
- Author(s)
  Uchibori R, Ninomiya S, Tsukahara T, Ido H, Teruya T, Ohmine K, Urabe M, Mizukami H, Kume A, Riviere I, Sadelain M, Brentjens RJ, Mineno J, Ozawa K.
- Organizer
  第18回日本遺伝子治療学会
- Place of Presentation
  岡山市
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] Development of switch promoters that would respond to activation signals from the chimeric antigen receptors.
- Author(s)
  Uchibori R, Ninomiya S, Tsukahara T, Ido H, Teruya T, Ohmine K, Urabe M, Mizukami H, Kume A, Riviere I, Sadelain M, Brentjens RJ, Mineno J, Ozawa K.
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] Development of switch promoters driven by activation signals from the chimeric antigen receptors.
- Author(s)
  Uchibori R, Ninomiya S, Tsukahara T, Ohmine K, Urabe M, Mizukami H, Kume A, Mineno J, Ozawa K.
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-24390247

1. OZAWA Keiya (30137707)

# of Collaborated Projects: 2 results

# of Collaborated Products: 20 results
2. URABE Masashi (40213516)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. TSUKAHARA Tomonori (10362120)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
4. OHMINE Ken (90316521)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
5. 久米晃啓

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
6. 川上浩一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Uchibori Ryosuke 内堀 亮介

内堀 亮介 ウチボリ リョウスケ

UCHIBORI Ryosuke 内堀 亮介

Research Projects

Research Products

Co-Researchers

Development of selective regulatory system for proliferation and persistence of CAR-T cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Development of CD269-CAR T cells for the adoptive immunotherapy of multiple myeloma.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of gene therapy for refractory non-Hodgkin lymphoma using T-cells expressing a chimeric antigen receptor

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of switch promoters driven by activation signals from the chimeric antigen receptors.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of gene therapy using bone-marrow-derived mesenchymal stem cells

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

[Journal Article] CAR-T cell（キメラ抗原受容体発現Ｔ細胞）Therapy2018

Author(s)

Journal Title

Data Source

[Journal Article] 多発性骨髄腫に対するキメラ抗原受容体T 細胞療法の可能性2017

Author(s)

Journal Title

NAID

Data Source

[Journal Article] 多発性骨髄腫に対するCAR-T細胞療法の開発研究2017

Author(s)

Journal Title

Data Source

[Journal Article] The Tol2 transposon system mediates the genetic engineering of T-cells with CD19-specific chimeric antigen receptors for B-cell malignancies2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Novel anti-tumor mechanism of galanin receptor type 2 in head and neck squamous cell carcinoma cells2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cancer gene therapy using mesenchymal stem cells.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] IL-21 is not necessary for anti-lymphoma effects of T cells expressing second-generation CD19-specific chimeric antigen receptors in a xenograft mouse model.2014

Author(s)

Journal Title

NAID

Data Source

[Journal Article] NF-κB activity regulates mesenchymal stem cell accumulation at tumor sites.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CD19 target-engineered T-cells accumulate at tumor lesions in human B-cell lymphoma xenograft mouse models2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Establishment and characterization of transplantable, luminescence labeled rat renal cell carcinoma cell lines2010

Uchibori Ryosuke 内堀亮介

内堀亮介ウチボリリョウスケ

UCHIBORI Ryosuke 内堀亮介