OKUWA Takako 大桑孝子

Researcher Number	20460347
Other IDs
Affiliation (Current)	2025: 金沢医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2021 – 2024: 金沢医科大学, 医学部, 助教 2015 – 2019: 金沢医科大学, 医学部, 助教 2014: 金沢医科大学, 医学部, 研究員 2010 – 2013: 金沢医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 49060:Virology-related / Virology Except Principal Investigator Virology
Keywords	Principal Investigator CRISPR/Cas9 / 感染受容体 / サフォードウイルス / sgRNAライブラリー / CRISPRスクリーニング / Saffold virus / 蛍光タンパク質発現組換えサフォードウイルス / cDNAライブラリー / UnaG発現組換えサフォードウイルス / 翻訳後修飾 / CM2蛋白 / C型インフルエンザウイルス … More Except Principal Investigator … More 持続感染 / Saffold ウイルス / 急性膵炎 / 膵臓 / 感染受容体 / ウイルス蛋白 / 膵炎 / 糖尿病 / Saffoldウイルス / 翻訳後修飾 / ＣＭ２蛋白 / 量体形成 / 翻訳後修飾部位 / CM2 / splicing / イオンチャネル / Ｃ型インフルエンザウイルス / スプライシング / 増殖過程 / packaging / uncoating / CM2蛋白 / C型インフルエンザウイルス Less

Identification and analysis of a second receptor for Safford virus using CRISPR screeningPrincipal Investigator
- Principal Investigator
  
  大桑孝子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Kanazawa Medical University
Functional analysis of Safford virus receptor candidate genes identified by CRISPR screeningPrincipal Investigator
- Principal Investigator
  
  OKUWA Takako
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Kanazawa Medical University
Identification and functional analysis of a cellular receptor for Saffold virusPrincipal Investigator
- Principal Investigator
  
  OKUWA Takako
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kanazawa Medical University
Will Saffold virus infection be a trigger of autoimmune disease (especially type 1 diabetes)?
- Principal Investigator
  
  HIMEDA Toshiki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kanazawa Medical University
Involvement of the CM2 ion channel activity in the influenza C virus replication cycle
- Principal Investigator
  
  MURAKI Yasushi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Iwate Medical University
  Kanazawa Medical University
Functional analysis of CM2 in influenza C virus replication by using the mutants of the posttranslational modification sitesPrincipal Investigator
- Principal Investigator
  
  OKUWA Takako
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  Kanazawa Medical University

All 2023 2021 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] Generation of a recombinant Saffold Virus expressing UnaG as a marker for the visualization of viral infection2023
- Author(s)
  Okuwa Takako、Himeda Toshiki、Utani Koichi、Higuchi Masaya
- Journal Title
  
  Virology Journal
  
  Volume: 20 Issue: 1 Pages: 175-175
- DOI
  10.1186/s12985-023-02142-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07045
[Journal Article] Saffold Cardiovirus Infection in a 2-Year-Old Boy with Acute Pancreatitis2017
- Author(s)
  Ito H, Miyagaki S, Sakaue S, Matsui F, Katsumi Y, Otabe O, Torii J, Itagaki T, Himeda T, Okuwa T, Ohara Y
- Journal Title
  
  Jpn J Infect Dis
  
  Volume: 70 Issue: 1 Pages: 105-107
- DOI
  10.7883/yoken.JJID.2015.488
- NAID
  130005296284
- ISSN
  1344-6304, 1884-2836
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460561
[Journal Article] The epitope sequence of S16, a monoclonal antibody against influenza C virus hemagglutinin-esterase fusion glycoprotein.2017
- Author(s)
  Okuwa T, Sasaki Y, Matsuzaki Y, Himeda T, Yoshino N, Hongo S, Ohara Y, Muraki Y.
- Journal Title
  
  Future Virol.
  
  Volume: 12 Issue: 3 Pages: 93-101
- DOI
  10.2217/fvl-2016-0105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460561, KAKENHI-PROJECT-16K08816
[Journal Article] Role(s) of Leader protein of Saffold virus.2014
- Author(s)
  Shimizu A, Himeda T, Okuwa T, Muraki Y, Ohara Y
- Journal Title
  
  Clin Exp Neuroimmunol
  
  Volume: 3 Issue: 3 Pages: 1-5
- DOI
  10.1111/cen3.12109
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590560, KAKENHI-PROJECT-24790449, KAKENHI-PROJECT-25460571, KAKENHI-PROJECT-26460561
[Journal Article] Possibility of neuropathogenesis of Saffold virus suggested from the in vitro virus persistence.2013
- Author(s)
  Himeda T, Okuwa T, Muraki Y, Ohara Y
- Journal Title
  
  Clin Exp Neuroimmunol
  
  Volume: 4 Issue: 2 Pages: 163-164
- DOI
  10.1111/cen3.12033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590560, KAKENHI-PROJECT-24790449
[Journal Article] Saffold virus type 3 (SAFV-3) persists in HeLa cells.2013
- Author(s)
  Himeda T, Hosomi T, Okuwa T, Muraki Y, Ohara Y
- Journal Title
  
  PLoS ONE
  
  Volume: 8 Issue: 1 Pages: e53194-e53194
- DOI
  10.1371/journal.pone.0053194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590560, KAKENHI-PROJECT-24790449, KAKENHI-PROJECT-25460571
[Journal Article] Effect of cysteine mutations in the extracellular domain of CM2 on the influenza C virus replication.2013
- Author(s)
  Muraki Y, Okuwa T, Himeda T, Hongo S, Ohara Y.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 4 Pages: e60510-e60510
- DOI
  10.1371/journal.pone.0060510
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590536, KAKENHI-PROJECT-24590560, KAKENHI-PROJECT-25460571
[Journal Article] Glycosylation of CM2 is important for efficient replication of influenza C virus.2012
- Author(s)
  Okuwa T
- Journal Title
  
  Virology
  
  Volume: 433 Issue: 1 Pages: 167-175
- DOI
  10.1016/j.virol.2012.08.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590560
[Journal Article] Palmitoylation of CM2 is dispensable to influenza C virus replication2011
- Author(s)
  Muraki Y, et al
- Journal Title
  
  Virus Reserch
  
  Volume: 157 Issue: 1 Pages: 99-105
- DOI
  10.1016/j.virusres.2011.02.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590505, KAKENHI-PROJECT-22590421, KAKENHI-PROJECT-22790439, KAKENHI-PROJECT-23590536
[Journal Article] Reverse Genetic Analysis of the Eecombination in Theilovirus based on the Infectious cDNA Clones2011
- Author(s)
  Himeda T, et al
- Journal Title
  
  J Plant Pathol Microbiol
  
  Volume: 2 Issue: 04 Pages: 4-4
- DOI
  10.4172/2157-7471.1000112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590505, KAKENHI-PROJECT-22590421, KAKENHI-PROJECT-22790439
[Journal Article] The Preparation of an infectious full-length cDNA clone of Saffold Virus2011
- Author(s)
  Himeda T., et al
- Journal Title
  
  Virol.J.
  
  Volume: 8 Issue: 1 Pages: 110-110
- DOI
  10.1186/1743-422x-8-110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590421, KAKENHI-PROJECT-22790439
[Journal Article] The anti-apoptotic protein L of Theiler's murine encephalomyelitis virus(TMEV) contains a mitochondrial targeting signal2011
- Author(s)
  Himeda T., Okuwa T., Nojiri M., Muraki Y. and Ohara Y.
- Journal Title
  
  Virus Res
  
  Volume: 155 Pages: 381-388
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790439
[Journal Article] Opposite effects of two nonstructural proteins of Theiler's murine encephalomyelitis virus regulates apoptotic cell death in BHK-21 cells.2010
- Author(s)
  Okuwa T., et al.
- Journal Title
  
  Microbiol.Immunol.
  
  Volume: 54 Pages: 639-643
- NAID
  10029546016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790439
[Journal Article] Activation of the PI3K. Akt pathway by human T cell leukemia virus type 1(HTLV-1) oncoprotein Tax increases Bcl3 expression, which is associated with enhanced growth of HTLV-1-infected T cells2010
- Author(s)
  Saito K., Saito M., Taniura N., Okuwa T. and Ohara Y
- Journal Title
  
  Virology
  
  Volume: 403 Issue: 2 Pages: 173-180
- DOI
  10.1016/j.virol.2010.04.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790439
[Journal Article] Opposite effects of two nonstructural proteins of Theiler's murine encephalomyelitis virus regulates apoptotic cell death in BHK-21 cells2010
- Author(s)
  Okuwa T., Taniura N., Saito M., Himeda T. and Ohara Y
- Journal Title
  
  Microbiol. Immunol
  
  Volume: 54 Issue: 10 Pages: 639-643
- DOI
  10.1111/j.1348-0421.2010.00260.x
- NAID
  10029546016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790439
[Journal Article] Cytokine/chemokine profile in J774 macrophage cells persistently infected with DA strain of Theiler's murine encephalomyelitis virus(TMEV)2010
- Author(s)
  Himeda T., Okuwa T., Muraki Y. and Ohara Y
- Journal Title
  
  J. Neurovirol
  
  Volume: 16 Issue: 3 Pages: 219-229
- DOI
  10.3109/13550284.2010.484040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790439
[Presentation] CRISPR/Cas9 システムを用いた Saffold virus 受容体の同定2023
- Author(s)
  大桑孝子, 姫田敏樹, 小林郷介, 野村奈美子, 宇谷公一, 小池智, 樋口雅也
- Organizer
  第70回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07045
[Presentation] CRISPR/Cas9システムを用いたSaffoldウイルス感染受容体同定の試み2021
- Author(s)
  大桑孝子、姫田敏樹、宇谷公一、小林郷介、小池智、樋口雅也
- Organizer
  第68回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07045
[Presentation] ニホンウナギ由来蛍光タンパク質UnaG発現Saffold virusの作製2019
- Author(s)
  大桑孝子、姫田敏樹、宇谷公一、樋口雅也
- Organizer
  第67回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08865
[Presentation] ニホンウナギ由来蛍光タンパク質UnaG発現サフォードウイルスの作製2018
- Author(s)
  大桑孝子、姫田敏樹、宇谷公一、樋口雅也
- Organizer
  第11回北陸合同バイオシンポジウム
- Data Source
  KAKENHI-PROJECT-17K08865
[Presentation] サフォードウイルスVP1カプシド蛋白質の分解機構の解析2018
- Author(s)
  大桑孝子、姫田敏樹、宇谷公一、樋口雅也
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K08865
[Presentation] サフォードウイルス感染受容体の探索2018
- Author(s)
  大桑孝子、姫田敏樹、宇谷公一、樋口雅也
- Organizer
  第1回がん・ウイルス研究会
- Data Source
  KAKENHI-PROJECT-17K08865
[Presentation] 蛍光タンパク質発現サフォードウイルスの作製2018
- Author(s)
  大桑孝子、姫田敏樹、宇谷公一、樋口雅也
- Organizer
  第55回日本細菌学会中部支部総会
- Data Source
  KAKENHI-PROJECT-17K08865
[Presentation] サフォードウイルスVP1蛋白の分解における他のウイルス蛋白関与2017
- Author(s)
  大桑孝子、姫田敏樹、宇谷公一、樋口雅也
- Organizer
  第54回日本細菌学会中部支部総会
- Data Source
  KAKENHI-PROJECT-17K08865
[Presentation] Saffold ウイルスLeader蛋白の機能解析2016
- Author(s)
  姫田敏樹、大桑孝子、樋口雅也
- Organizer
  第64回日本ウイルス学会学術集会
- Place of Presentation
  札幌コンベンションセンター（北海道・札幌市）
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-26460561
[Presentation] サフォードウイルスVP1蛋白質の分解に関わるアミノ酸領域の探索2015
- Author(s)
  姫田敏樹、大桑孝子
- Organizer
  第52回　日本細菌学会中部支部総会
- Place of Presentation
  名古屋市立大学（愛知県名古屋市）
- Year and Date
  2015-10-23
- Data Source
  KAKENHI-PROJECT-26460561
[Presentation] SaffoldウイルスVP1蛋白質の不安定性に関する解析2015
- Author(s)
  大桑孝子、姫田敏樹
- Organizer
  第63回　日本ウイルス学会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-26460561
[Presentation] CM2の膜貫通領域に変異をもつＣ型インフルエンザウイルスの解析2014
- Author(s)
  大原義朗, 村木靖, 姫田敏樹, 大桑孝子
- Organizer
  平成26年度北陸腸内細菌研究会
- Place of Presentation
  ホテル日航金沢（金沢市）
- Year and Date
  2014-07-19
- Data Source
  KAKENHI-PROJECT-24590560
[Presentation] Analysis of influenza C virus possessing substitutions in its CM2 transmembrane region.2013
- Author(s)
  Muraki Y, Okuwa T, Noda T, Himeda T, Hongo S, Ohara Y
- Organizer
  Options for the Control of Influenza VIII
- Place of Presentation
  International Convention Centre, Cape Town, South Africa
- Data Source
  KAKENHI-PROJECT-24590560
[Presentation] 膜貫通領域を置換したCM2 をもつＣ型インフルエンザウイルス．2013
- Author(s)
  村木靖, 大桑孝子, 野田岳志, 姫田敏樹, 本郷誠治, 大原義朗
- Organizer
  第50回日本細菌学会中部支部総会
- Place of Presentation
  ホテル竹島、愛知県蒲郡市
- Data Source
  KAKENHI-PROJECT-24590560
[Presentation] CM2 の膜貫通領域を置換したC型インフルエンザウイルスの解析2013
- Author(s)
  村木靖, 大桑孝子, 野田岳志, 姫田敏樹, 本郷誠治, 大原義朗
- Organizer
  第27回インフルエンザ研究者交流の会シンポジウム
- Place of Presentation
  北海道大学講堂、札幌市
- Data Source
  KAKENHI-PROJECT-24590560
[Presentation] CM2の膜貫通領域がC型インフルエンザウイルスの形態と増殖に与える影響．2013
- Author(s)
  村木靖, 大桑孝子, 野田岳志, 姫田敏樹, 本郷誠治, 大原義朗
- Organizer
  第61回日本ウイルス学会学術集会総会
- Place of Presentation
  神戸国際会議場、神戸市
- Data Source
  KAKENHI-PROJECT-24590560
[Presentation] Disulphide-linked CM2 oligomers are required for efficient replication of influenza C virus.2013
- Author(s)
  Muraki Y, Okuwa T, Himeda T, Hongo S, Ohara Y
- Organizer
  15th International Negative Strand Virus Meeting
- Place of Presentation
  Palacio de Exposiciones y Congresos, Granada, Spain
- Data Source
  KAKENHI-PROJECT-24590560
[Presentation] C型インフルエンザウイルス感染性粒子産生におけるCM2蛋白の糖鎖付加の意義2011
- Author(s)
  大桑孝子
- Organizer
  第48回細菌学会中部支部総会
- Place of Presentation
  名古屋大学シンポジオンホール(愛知県)
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-22790439
[Presentation] Glycosylation of influenza C virus CM2 protein affects the early phase of viral replication2011
- Author(s)
  Takako Okuwa
- Organizer
  IUMS 2011 Sapporo
- Place of Presentation
  札幌コンベンションセンター(北海道)
- Year and Date
  2011-09-13
- Data Source
  KAKENHI-PROJECT-22790439
[Presentation] Glycosylation of influen za C virus CM2 protein affects the ea rly phase of viral replication2011
- Author(s)
  Takako Okuwa
- Organizer
  IUMS 2011 Sapporo
- Place of Presentation
  札幌コンベンションセンター(北海道)
- Year and Date
  2011-09-13
- Data Source
  KAKENHI-PROJECT-22790439
[Presentation] C型インフルエンザウイルスのCM2蛋白糖鎖付加部位変異体の作製と解析2011
- Author(s)
  大桑孝子
- Organizer
  第25回インフルエンザ研究者交流の会シンポジウム
- Place of Presentation
  富山国際会議場(富山県)
- Year and Date
  2011-06-04
- Data Source
  KAKENHI-PROJECT-22790439
[Presentation] C型インフルエンザウイルスの増殖におけるCM2蛋白の糖鎖付加の意義2010
- Author(s)
  大桑孝子
- Organizer
  第58回日本ウイルス学会学術集会
- Place of Presentation
  あわぎんホール(徳島県)
- Year and Date
  2010-11-08
- Data Source
  KAKENHI-PROJECT-22790439
[Presentation] Ｃ型インフルエンザウイルスHEFのレセプター結合部位変異体の解析
- Author(s)
  大桑孝子, 村木靖, 姫田敏樹, 大原義朗
- Organizer
  第28回インフルエンザ研究者交流の会シンポジウム
- Place of Presentation
  鳥取市総合福祉センターさざんか会館(鳥取市)
- Year and Date
  2014-07-04 – 2014-07-06
- Data Source
  KAKENHI-PROJECT-24590560
[Presentation] Ｃ型インフルエンザウイルスＭ遺伝子のスプライシング効率と増殖の関連
- Author(s)
  村木靖, 大桑孝子, 野田岳志, 姫田敏樹, 本郷誠治, 大原義朗
- Organizer
  第28回インフルエンザ研究者交流の会シンポジウム
- Place of Presentation
  鳥取市総合福祉センターさざんか会館(鳥取市)
- Year and Date
  2014-07-04 – 2014-07-06
- Data Source
  KAKENHI-PROJECT-24590560
[Presentation] 1型糖尿病剖検例における抗Saffoldウイルス抗体染色性
- Author(s)
  姫田敏樹、大桑孝子、村木靖、大原義朗
- Organizer
  第62回　日本ウイルス学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-26460561
[Presentation] レセプター結合部位に変異をもつＣ型インフルエンザウイルスHEF蛋白の解析
- Author(s)
  大桑孝子, 村木靖, 姫田敏樹, 大原義朗
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  パシフィコ横浜会議センター（横浜市）
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-24590560
[Presentation] 1型糖尿病剖検例における抗Saffordウイルス抗体染色性
- Author(s)
  姫田敏樹, 大桑孝子, 村木靖,大原義朗
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  パシフィコ横浜会議センター（横浜市）
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-24590560
[Presentation] タイラーマウス脳脊髄炎ウイルス非構成蛋白による細胞死制御機構
- Author(s)
  塩浜康雄, 姫田敏樹, 大桑孝子, 村木靖, 谷浦直子, 大原義朗, 齊藤峰輝
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  パシフィコ横浜会議センター（横浜市）
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-24590560
[Presentation] Ｃ型インフルエンザウイルスのＭ遺伝子のsplicing効率が粒子の形態に与える影響
- Author(s)
  村木靖, 大桑孝子, 野田岳志, 姫田敏樹, 本郷誠治, 大原義朗
- Organizer
  第68回日本細菌学会東北支部総会
- Place of Presentation
  東北大学片平さくらホール（仙台市）
- Year and Date
  2014-08-22 – 2014-08-23
- Data Source
  KAKENHI-PROJECT-24590560
[Presentation] 1型糖尿病を対象としたSaffordウイルス感染の検索
- Author(s)
  姫田敏樹, 大桑孝子, 村木靖,大原義朗
- Organizer
  第68回日本細菌学会東北支部総会
- Place of Presentation
  東北大学片平さくらホール（仙台市）
- Year and Date
  2014-08-22 – 2014-08-23
- Data Source
  KAKENHI-PROJECT-24590560
[Presentation] Ｃ型インフルエンザウイルスのＭ遺伝子のsplicing効率が粒子の形態に与える影響
- Author(s)
  村木靖, 大桑孝子, 野田岳志, 姫田敏樹, 本郷誠治, 大原義朗
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  パシフィコ横浜会議センター（横浜市）
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-24590560
[Presentation] タイラーウイルス非構成蛋白の機能解析から示唆される細胞死制御機構
- Author(s)
  姫田敏樹、齊藤峰輝、大桑孝子、村木靖、谷浦直子、大原義朗
- Organizer
  第18回日本神経ウイルス研究会
- Place of Presentation
  アクトシティ浜松（静岡県浜松市）
- Year and Date
  2014-06-20 – 2014-06-21
- Data Source
  KAKENHI-PROJECT-26460561

1. MURAKI Yasushi (00241688)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
2. HONGO Seiji (90229245)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
3. NODA Takeshi (00422410)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
4. HIMEDA Toshiki (80340008)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results

OKUWA Takako 大桑 孝子

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Identification and analysis of a second receptor for Safford virus using CRISPR screeningPrincipal Investigator

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Functional analysis of Safford virus receptor candidate genes identified by CRISPR screeningPrincipal Investigator

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Identification and functional analysis of a cellular receptor for Saffold virusPrincipal Investigator

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Will Saffold virus infection be a trigger of autoimmune disease (especially type 1 diabetes)?

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Involvement of the CM2 ion channel activity in the influenza C virus replication cycle

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Functional analysis of CM2 in influenza C virus replication by using the mutants of the posttranslational modification sitesPrincipal Investigator

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[Journal Article] Generation of a recombinant Saffold Virus expressing UnaG as a marker for the visualization of viral infection2023

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[Journal Article] Saffold Cardiovirus Infection in a 2-Year-Old Boy with Acute Pancreatitis2017

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[Journal Article] The epitope sequence of S16, a monoclonal antibody against influenza C virus hemagglutinin-esterase fusion glycoprotein.2017

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[Journal Article] Role(s) of Leader protein of Saffold virus.2014

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[Journal Article] Possibility of neuropathogenesis of Saffold virus suggested from the in vitro virus persistence.2013

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[Journal Article] Saffold virus type 3 (SAFV-3) persists in HeLa cells.2013

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[Journal Article] Effect of cysteine mutations in the extracellular domain of CM2 on the influenza C virus replication.2013

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[Journal Article] Glycosylation of CM2 is important for efficient replication of influenza C virus.2012

Author(s)

OKUWA Takako 大桑孝子