MITSUNAGA Shuichi 光永修一

… Alternative Names

光永修一ミツナガシュウイチ

Less

Researcher Number	20466197
Affiliation (Current)	2025: 国立研究開発法人国立がん研究センター, 東病院, 医長
Affiliation (based on the past Project Information) *help	2018 – 2022: 国立研究開発法人国立がん研究センター, 東病院, 医長 2016: 国立研究開発法人国立がん研究センター, 東病院, 医長 2015: 国立研究開発法人国立がん研究センター, 先端医療開発センター, 医長 2013 – 2014: 独立行政法人国立がん研究センター, その他部局等, 研究員 2012 – 2013: 独立行政法人国立がん研究センター, 東病院, 医員 2010 – 2011: 独立行政法人国立がん研究センター, 臨床開発センター, 研究員
Review Section/Research Field	Principal Investigator General internal medicine (including Psychosomatic medicine) / General internal medicine(including psychosomatic medicine) Except Principal Investigator Medium-sized Section 90:Biomedical engineering and related fields
Keywords	Principal Investigator マウスモデル / 神経浸潤 / 悪液質 / 膵がん / 緩和医療 / IL-6 / 疼痛 / S100A9 / S100P / アストロサイト … More / CCL7 / S100A4 / RAGE / 炎症性サイトカイン / インターロイキン6 … More Except Principal Investigator 放射線治療 / HPLC分析 / リポソームCu-64 / セラノスティックス / 放射性核種 / radio-theranostics / ラジオセラノスティックス / 内用療法 / radiotheranostics / がん / 核医学イメージング / 内用放射線治療 / 錯体 / リポソーム / がん治療 / 核医学画像診断 / 核医学治療 / ラジオセラノスティクス Less

Development of innovative radionuclide therapy and radio-theranostics for enabling cure of advance solid tumors
- Principal Investigator
  
  Umeda Izumi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokyo
Cancer cachexia via cancer-nerve closstalk in pancreatic cancerPrincipal Investigator
- Principal Investigator
  
  Mitsunaga Shuichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  National Cancer Center Japan
Molecular mechanism of astrocyte-related cachexia and pain due to neural invasion of pancreatic cancerPrincipal Investigator
- Principal Investigator
  
  MITSUNAGA Shuichi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  National Center of Neurology and Psychiatry
Innovation of anti-cachectic therapy with anti-tumor effect for pancreatic cancerPrincipal Investigator
- Principal Investigator
  
  MITSUNAGA Shuichi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East

All 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Book Patent

[Book] 肝細胞癌に対するソラフェニブチームネクサバール-国立がんセンター東病院のチーム医療-2010
- Author(s)
  光永修一, 他(Team Nexavar)
- Total Pages
  111
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-22790624
[Book] 膵がん患者の「るいそう」とIL-6、腫瘍内科2010
- Author(s)
  光永修一
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-22790624
[Book] 特集膵・胆道癌における分子標的治療の動向膵癌におけるIL-6の発現と治療応用、胆と膵2010
- Author(s)
  光永修一
- Publisher
  医学図書出版株式会社
- Data Source
  KAKENHI-PROJECT-22790624
[Book] あらゆる病態・症例に対応できる消化器がん化学療法の実践2010
- Author(s)
  光永修一, 他
- Total Pages
  334
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22790624
[Book] 膵がん患者の「るいそう」とIL-6.腫瘍内科2010
- Author(s)
  光永修一
- Total Pages
  7
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-22790624
[Book] 特集膵・胆道癌における分子標的治療の動向膵癌におけるIL-6の発現と治療応用胆と膵2010
- Author(s)
  光永修一
- Total Pages
  9
- Publisher
  医学図書出版株式会社
- Data Source
  KAKENHI-PROJECT-22790624
[Journal Article] Multicenter, Open-Label, Phase I/II Study of Tocilizumab, an Anti-Interleukin-6 Receptor Monoclonal Antibody, Combined with Gemcitabine in Patients with Advanced Pancreatic Cancer.2017
- Author(s)
  Mitsunaga S
- Journal Title
  
  J Med Diagn Meth
  
  Volume: 6 Issue: 01 Pages: 234-234
- DOI
  10.4172/2168-9784.1000234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460930
[Journal Article] C-Reactive Protein Level Is an Indicator of the Aggressiveness of Advanced Pancreatic Cancer.2016
- Author(s)
  Mitsunaga S, Ikeda M, Shimizu S, Ohno I, Takahashi H, Okuyama H, Ueno H, Morizane C, Kondo S, Sakamoto Y, Okusaka T, Ochiai A.
- Journal Title
  
  Pancreas
  
  Volume: 45 Issue: 1 Pages: 110-116
- DOI
  10.1097/mpa.0000000000000465
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26860537, KAKENHI-PROJECT-26460930
[Journal Article] Characterization of Patients With Advanced Pancreatic Cancer and High Serum Interleukin-6 Levels.2015
- Author(s)
  Miura T, Mitsunaga S,
- Journal Title
  
  Pancreas
  
  Volume: 44 Issue: 5 Pages: 756-763
- DOI
  10.1097/mpa.0000000000000335
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460930
[Journal Article] Characterization of Patients With Advanced Pancreatic Cancer and High Serum Interleukin-6 Levels.2015
- Author(s)
  Miura T, Mitsunaga S, et al.
- Journal Title
  
  Pancreas
  
  Volume: Epub ahead of print
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460930
[Journal Article] Prognostic impact of M2 macrophages at neural invasion in patients with invasive ductal carcinoma of the pancreas.2014
- Author(s)
  Sugimoto M, Mitsunaga S, Yoshikawa K, Kato Y, Gotohda N, Takahashi S, Konishi M, Ikeda M, Kojima M, Ochiai A, Kaneko H.
- Journal Title
  
  Eur J Cancer
  
  Volume: 50(11) Issue: 11 Pages: 1900-8
- DOI
  10.1016/j.ejca.2014.04.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590458, KAKENHI-PROJECT-24790669, KAKENHI-PROJECT-26460930
[Journal Article] Prognostic impact of M2 macrophages at neural invasion in patients with invasive ductal carcinoma of the pancreas2014
- Author(s)
  Sugimoto M, Mitsunaga S, Yoshikawa K, Kato Y, Gotohda N, Takahashi S, Konishi M, Ikeda M, Kojima M, Ochiai A, Kaneko H
- Journal Title
  
  Eur J Cancer
  
  Volume: 50(11) Pages: 1900-8
- Data Source
  KAKENHI-PROJECT-24790669
[Journal Article] Serum levels of IL-6 and IL-1β can predict the efficacy of gemcitabine in patients with advanced pancreatic cancer.2013
- Author(s)
  Mitsunaga S
- Journal Title
  
  Br J Cancer
  
  Volume: 108(10) Issue: 10 Pages: 2063-2069
- DOI
  10.1038/bjc.2013.174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790669
[Journal Article] Serum levels of IL-6 and IL-1βcan predict the efficacy of gemcitabine in patients with advanced pancreatic cancer2013
- Author(s)
  Mitsunaga S, Ikeda M, Shimizu S, Ohno I, Furuse J, Inagaki M, Higashi S, Kato H, Terao K, Ochiai A
- Journal Title
  
  Br J Cancer
  
  Volume: 108(10) Pages: 2063-9
- Data Source
  KAKENHI-PROJECT-24790669
[Journal Article] Remarkable tumor lysis in a hepatocellular carcinoma patient immediately following glypican-3-derived peptide vaccination: An autopsy case.2013
- Author(s)
  Sawada Y, Yoshikawa T, Fujii S, Mitsunaga S, Nobuoka D, Mizuno S, Takahashi M, Yamauchi C, Endo I, Nakatsura T.
- Journal Title
  
  Hum Vaccin Immunother.
  
  Volume: 9(7)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790669
[Journal Article] Associations of interleukin-6 with vegetative but not affective depressive symptoms in terminally ill cancer patients2013
- Author(s)
  Inagaki M, Akechi T, Okuyama T, Sugawara Y, Kinoshita H, Shima Y, Terao K, Mitsunaga S, Ochiai A, Uchitomi Y
- Volume
  21(8)
- Pages
  2097-106
- Data Source
  KAKENHI-PROJECT-24790669
[Journal Article] Associations of interleukin-6 with vegetative but not affective depressive symptoms in terminally ill cancer patients.2013
- Author(s)
  Inagaki M, Akechi T, Okuyama T, Sugawara Y, Kinoshita H, Shima Y, Terao K, Mitsunaga S, Ochiai A, Uchitomi Y.
- Journal Title
  
  Support Care Cancer.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790669
[Journal Article] Neural invasion induces cachexia via astrocytic activation of neural route in pancreatic cancer2012
- Author(s)
  Imoto A, Mitsunaga S, Inagaki M, Aoyagi K, Sasaki H, Ikeda M, Nakachi K, Higuchi K, Ochiai A
- Journal Title
  
  Int J Cancer
  
  Volume: 131(12) Pages: 2795-807
- NAID
  40019958265
- Data Source
  KAKENHI-PROJECT-24790669
[Journal Article] Phase I/II study of gemcitabine as a fixed dose rate infusion and S-1 combination therapy (FGS) in gemcitabine-refractory pancreatic cancer patients.2012
- Author(s)
  Morizane C, Okusaka T, Ueno H, Kondo S, Ikeda M, Furuse J, Shinichi O, Nakachi K, Mitsunaga S, Kojima Y, Suzuki E, Ueno M, Yamaguchi T.
- Journal Title
  
  Cancer Chemother Pharmacol.
  
  Volume: 69(4) Issue: 4 Pages: 957-64
- DOI
  10.1007/s00280-011-1786-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790669
[Journal Article] Impact of tumor-associated macrophages on invasive ductal carcinoma of the pancreas head.2012
- Author(s)
  Yoshikawa K, Mitsunaga S, Kinoshita T, Konishi M, Takahashi S, Gotohda N, Kato Y, Aizawa M, Ochiai A.
- Journal Title
  
  Cancer Sci.
  
  Volume: 103(11) Pages: 2012-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790669
[Journal Article] Treatment outcome for systemic chemotherapy for recurrent pancreatic cancer after postoperative adjuvant chemotherapy.2012
- Author(s)
  Taniyama TK, Morizane C, Nakachi K, Nara S, Ueno H, Kondo S, Kosuge T, Shimada K, Esaki M, Ikeda M, Mitsunaga S, Kinoshita T, Konishi M, Takahashi S, Okusaka T.
- Journal Title
  
  Pancreatology
  
  Volume: 12(5) Issue: 5 Pages: 428-33
- DOI
  10.1016/j.pan.2012.07.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790669
[Journal Article] Neural invasion induces cachexia via astrocytic activation of neural route in pancreatic cancer2012
- Author(s)
  Imoto A, Mitsunaga S
- Journal Title
  
  Int J Cancer
  
  Volume: 131(12) Issue: 12 Pages: 2795-807
- DOI
  10.1002/ijc.27594
- NAID
  40019958265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790624, KAKENHI-PROJECT-24790669
[Journal Article] Impact of tumor-associated macrophages on invasive ductal carcinoma of the pancreas head2012
- Author(s)
  Yoshikawa K, Mitsunaga S, Kinoshita T, Konishi M, Takahashi S, Gotohda N, Kato Y, Aizawa M, Ochiai A
- Journal Title
  
  Cancer Sci
  
  Volume: 103(11) Pages: 2012-20
- Data Source
  KAKENHI-PROJECT-24790669
[Journal Article] Construction and Validation of a Prognostic Index for Patients With Metastatic Pancreatic Adenocarcinoma2011
- Author(s)
  Morizane C, Mitsunaga S, et al
- Journal Title
  
  Pancreas
  
  Volume: 40(3) Pages: 415-421
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790624
[Journal Article] Construction and Validation of a Prognostic Index for Patients With Metastatic Pancreatic Adenocarcinoma2011
- Author(s)
  Morizane C, Mitsunaga S
- Journal Title
  
  Pancreas
  
  Volume: Vol.40、No.3 Pages: 415-421
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790624
[Journal Article] Nerve invasion distance is dependent on laminin gamma2 in tumors of pancreatic cancer2010
- Author(s)
  Mitsunaga S
- Journal Title
  
  Int J Cancer
  
  Volume: Vol.127、No.4 Pages: 805-819
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790624
[Journal Article] Nerve invasion distance is dependent on laminin gamma2 in tumors of pancreatic cancer.2010
- Author(s)
  Mitsunaga S
- Journal Title
  
  Int J Cancer
  
  Volume: 127 Pages: 805-819
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790624
[Patent] 膵癌治療剤2011
- Inventor(s)
  光永修一
- Industrial Property Rights Holder
  独立行政法人国立がん研究センター中外製薬株式会社
- Filing Date
  2011-05-27
- Overseas
- Data Source
  KAKENHI-PROJECT-22790624
[Patent] 神経浸潤抑制剤2011
- Inventor(s)
  光永修一
- Industrial Property Rights Holder
  独立行政法人国立がん研究センター・中外製薬株式会社
- Filing Date
  2011-01-04
- Overseas
- Data Source
  KAKENHI-PROJECT-22790624
[Patent] 神経浸潤抑制剤2011
- Inventor(s)
  光永修一
- Industrial Property Rights Holder
  独立行政法人国立がん研究センター・中外製薬株式会社
- Filing Date
  2011-01-30
- Overseas
- Data Source
  KAKENHI-PROJECT-22790624
[Patent] 膵癌治療剤2011
- Inventor(s)
  光永修一, 落合敦志, 池田公史
- Industrial Property Rights Holder
  独立行政法人国立がん研究センター中外製薬株式会社
- Filing Date
  2011-05-27
- Overseas
- Data Source
  KAKENHI-PROJECT-22790624
[Patent] 神経浸潤抑制剤2010
- Inventor(s)
  光永修一
- Industrial Property Rights Holder
  独立行政法人国立がん研究センター・中外製薬株式会社
- Filing Date
  2010-12-02
- Overseas
- Data Source
  KAKENHI-PROJECT-22790624
[Patent] 神経浸潤抑制剤2010
- Inventor(s)
  光永修一
- Industrial Property Rights Holder
  独立行政法人国立がん研究センター・中外製薬株式会社
- Filing Date
  2010-12-02
- Data Source
  KAKENHI-PROJECT-22790624
[Patent] 膵がん治療剤2010
- Inventor(s)
  光永修一
- Industrial Property Rights Holder
  光永修一・中外製薬株式会社
- Filing Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-22790624
[Patent] 神経浸潤抑制剤2010
- Inventor(s)
  光永修一
- Industrial Property Rights Holder
  独立行政法人国立がん研究センター・中外製薬株式会社
- Filing Date
  2010-12-03
- Overseas
- Data Source
  KAKENHI-PROJECT-22790624
[Patent] 神経浸潤抑制剤2010
- Inventor(s)
  光永修一
- Industrial Property Rights Holder
  独立行政法人国立がん研究センター・中外製薬株式会社
- Filing Date
  2010-12-03
- Overseas
- Data Source
  KAKENHI-PROJECT-22790624
[Patent] 膵がん治療剤2010
- Inventor(s)
  光永修一
- Industrial Property Rights Holder
  光永修一・中外製薬株式会社
- Industrial Property Number
  2010-122838
- Filing Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-22790624
[Patent] 神経浸潤抑制剤2010
- Inventor(s)
  光永修一
- Industrial Property Rights Holder
  独立行政法人国立がん研究センター・中外製薬株式会社
- Filing Date
  2010-11-09
- Overseas
- Data Source
  KAKENHI-PROJECT-22790624
[Patent] 神経浸潤抑制剤2010
- Inventor(s)
  光永修一
- Industrial Property Rights Holder
  独立行政法人国立がん研究センター・中外製薬株式会社・光永修一・落合淳志
- Filing Date
  2010-12-03
- Overseas
- Data Source
  KAKENHI-PROJECT-22790624
[Patent] 神経浸潤抑制剤2010
- Inventor(s)
  光永修一
- Industrial Property Rights Holder
  独立行政法人国立がん研究センター・中外製薬株式会社
- Filing Date
  2010-12-27
- Overseas
- Data Source
  KAKENHI-PROJECT-22790624
[Presentation] CHARACTERIZATION OF ADVANCED PANCREATIC CANCER PATIENTS SHOWING A DECREASE OF THE SKELETAL MUSCLE MASS WHILE RECEIVING FIRST-LINE CHEMOTHERAPY2016
- Author(s)
  Tatematsu N, Mitsunaga S.
- Organizer
  Multinational Association of Supportive Care in Cancer
- Place of Presentation
  Adelaide, Australia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460930
[Presentation] DETERIORATION OF CACHEXIA-RELATED FACTORS AFTER FIRST-LINE CHEMOTHERAPY FOR ADVANCED PANCREATIC CANCER2016
- Author(s)
  Mitsunaga S.
- Organizer
  Multinational Association of Supportive Care in Cancer
- Place of Presentation
  Adelaide, Australia
- Year and Date
  2016-06-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460930
[Presentation] 膵癌肝転移におけるreplacement growth patternは膵癌悪性度の指標となる2015
- Author(s)
  光永修一
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26460930
[Presentation] S100A8/A9 as a potent serological marker in monitoring the activity of chemotherapy in pancreatic cancer.2015
- Author(s)
  Mitsunaga S
- Organizer
  2015 ASCO Annual Meeting
- Place of Presentation
  Chicago　アメリカ合衆国
- Year and Date
  2015-05-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460930
[Presentation] 3.予後不良な膵癌患者の腫瘍細胞で高発現するサイトケラチン6は、IL-6/STAT3経路の制御を受けている　（口演）2014
- Author(s)
  光永　修一
- Organizer
  第73回日本癌学会学術集会
- Place of Presentation
  日本
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-26460930
[Presentation] Phase I study of safety, pharmacokinetics, and efficacy of TSU-68 plus S-1 combination in patients with advanced hepatocellular carcinoma2013
- Author(s)
  Masafumi Ikeda, Shuichiro Shiina, Kohei Nakachi, Shuichi Mitsunaga, Satoshi Shimizu, Yasushi Kojima, Hideki Ueno, Chigusa Morizane, Shunsuke Kondo, Yasunari Sakamoto, Ryosuke Tateishi, Yoshinari Asaoka, Kazuhiko Koike, Hitoshi Arioka, Takuji Okusaka
- Organizer
  ASCO-GI2013 Gastrointestinal Cancers Symposium
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-24790669
[Presentation] 血小板低値の肝細胞癌患者に対するSorafenib2013
- Author(s)
  清水怜、桑原明子、奥山浩之、高橋秀明、大野泉、光永修一、篠原旭、小林美沙樹、船崎秀樹、近藤俊輔、森実千種、上野秀樹、奥坂拓志、池田公史
- Organizer
  第7回日本肝がん分子標的治療研究会
- Place of Presentation
  岐阜市
- Year and Date
  2013-01-19
- Data Source
  KAKENHI-PROJECT-24790669
[Presentation] ゲムシタビン耐性進行膵癌に対するS-1療法の3週レジメンの有効性と安全性―6週レジメンとの比較―2013
- Author(s)
  田中弘人、光永修一、小林美沙樹、船崎秀樹、高橋秀明、大野泉、清水怜、和泉啓司郎、池田公史
- Organizer
  第11回日本臨床腫瘍学会学術集会
- Place of Presentation
  仙台市
- Year and Date
  2013-08-30
- Data Source
  KAKENHI-PROJECT-24790669
[Presentation] Characterization of patient with high serum level of IL-6 in advanced panceratic cancer2013
- Author(s)
  三浦智史、光永修一、清水怜、大野泉、高橋秀明、奥山浩之、桑原明子、池田公史
- Organizer
  第11回日本臨床腫瘍学会学術集会
- Place of Presentation
  仙台市
- Year and Date
  2013-08-29
- Data Source
  KAKENHI-PROJECT-24790669
[Presentation] 進行膵がんにおける塩酸ゲムシタビン療法の有害事象と炎症性サイトカイン・タンパクの関連2013
- Author(s)
  奥山浩之、光永修一、桑原明子、高橋秀明、大野泉、清水怜、池田公史
- Organizer
  第11回日本臨床腫瘍学会学術集会
- Place of Presentation
  仙台市
- Year and Date
  2013-08-29
- Data Source
  KAKENHI-PROJECT-24790669
[Presentation] 進行肝細胞癌患者におけるSorafenib療法-C型肝炎とB型肝炎の背景肝の違いによる有効性と安全性の検討―2013
- Author(s)
  篠原旭、奥山浩之、高橋秀明、小林美沙樹、船崎秀樹、桑原明子、大野泉、清水怜、光永修一、池田公史、市田泰彦、和泉啓司郎
- Organizer
  第7回日本肝がん分子標的治療研究会
- Place of Presentation
  岐阜市
- Year and Date
  2013-01-19
- Data Source
  KAKENHI-PROJECT-24790669
[Presentation] Phase I/II study of lenvatinib (E7080), a multitargeted tyrosine kinase inhibitor, in patients (pts) with advanced hepatocellular carcinoma (HCC) : Phase I results2013
- Author(s)
  Shuichi Mitsunaga, Masafumi Ikeda, Hideki Ueno, Kohei Nakachi, Chigusa Morizane, Shunsuke Kondo, Satoshi Shimizu, Yasushi Kojima, Takuya Suzuki, Toshiyuki Tamai, James P. O'Brien, Takuji Okusaka
- Organizer
  ASCO-GI2013 Gastrointestinal Cancers Symposium
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-24790669
[Presentation] 胆道がんの患者背景と治療成績の変遷―国立がん研究センター東病院1031例の検討―2013
- Author(s)
  4.光永修一、池田公史、清水怜、大野泉、高橋秀明、奥山浩之、桑原明子、加藤祐一郎、落合敦志、小西大
- Organizer
  第11回日本臨床腫瘍学会学術集会
- Place of Presentation
  仙台市
- Year and Date
  2013-08-29
- Data Source
  KAKENHI-PROJECT-24790669
[Presentation] Phase I/II study of lenvatinib (E7080), a multitargeted tyrosine kinase inhibitor, in patients (pts) with advanced hepatocellular carcinoma (HCC): Phase I results.2013
- Author(s)
  Shuichi Mitsunaga, Masafumi Ikeda, Hideki Ueno, Kohei Nakachi, Chigusa Morizane, Shunsuke Kondo, Satoshi Shimizu, Yasushi Kojima, Takuya Suzuki, Toshiyuki Tamai,et al.
- Organizer
  ASCO-GI2013 Gastrointestinal Cancers Symposium
- Place of Presentation
  San Francisco, America
- Data Source
  KAKENHI-PROJECT-24790669
[Presentation] 肝動脈化学塞栓術に不応の肝細胞癌に対するソラフェニブの有効性-肝動注化学療法との比較-2013
- Author(s)
  桑原明子、池田公史、光永修一、清水怜、大野泉、高橋秀明、奥山浩之、近藤俊輔、森実千種、上野秀樹、佐竹光夫、荒井保明、奥坂拓志
- Organizer
  第7回日本肝がん分子標的治療研究会
- Place of Presentation
  岐阜市
- Year and Date
  2013-01-19
- Data Source
  KAKENHI-PROJECT-24790669
[Presentation] 肝転移を有する膵腺房細胞癌に対しゲムシタビン塩酸塩とS-1併用療法を行った2例.2012
- Author(s)
  桑原明子、光永修一、清水怜、大野泉、高橋秀明、奥山浩之、池田公史.
- Organizer
  第320回　日本消化器病学会　関東支部例会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790669
[Presentation] 進行膵がんにおける腹腔動脈および上腸間膜動脈周囲浸潤の臨床的意義．2012
- Author(s)
  光永修一、池田公史、大野泉、清水怜、高橋秀明、奥山浩之、桑原明子、奥坂拓志、上野秀樹、森実千種、近藤俊輔、落合淳志．
- Organizer
  第10回日本臨床腫瘍学会学術集会.
- Place of Presentation
  大阪市
- Data Source
  KAKENHI-PROJECT-24790669
[Presentation] 進行膵がん患者に対する2次化学療法としてのS-1療法の早期中止に関わる因子解析．2012
- Author(s)
  田中弘人、光永修一、小林美沙樹、船崎秀樹、市田泰彦、高橋秀明、大野泉、清水怜、池田公史、和泉啓司郎．
- Organizer
  第10回日本臨床腫瘍学会学術集会.
- Place of Presentation
  大阪市
- Data Source
  KAKENHI-PROJECT-24790669
[Presentation] 膵がん化学療法において治療前デスアシルグレリン値は消化器症状の予測因子である．2012
- Author(s)
  三浦智史、光永修一、松元信弘、中里雅光、大野泉、清水怜、高橋秀明、奥山浩之、桑原明子、池田公史．
- Organizer
  第10回日本臨床腫瘍学会学術集会.
- Place of Presentation
  大阪市
- Data Source
  KAKENHI-PROJECT-24790669
[Presentation] 80歳以上の高齢者の切除不能膵癌症例に対するゲムシタビン療法の有効性と忍容性2012
- Author(s)
  小林美沙樹、奥山浩之、船崎秀樹、桑原明子、高橋秀明、大野泉、清水怜、光永修一、池田公史、市田泰彦、和泉啓司郎
- Organizer
  第50回日本癌治療学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2012-10-25
- Data Source
  KAKENHI-PROJECT-24790669
[Presentation] 膵癌化学療法において腫瘍制御予測因子となりうる症状変動の検討．2012
- Author(s)
  桑原明子、光永修一、池田公史、大野泉、清水怜、高橋秀明、奥山浩之、奥坂拓志、上野秀樹、森実千種、近藤俊輔．
- Organizer
  第10回日本臨床腫瘍学会学術集会.
- Place of Presentation
  大阪市
- Data Source
  KAKENHI-PROJECT-24790669
[Presentation] Use of elevated IL-1 to predict prognosis in patients with advanced pancreatic cancer with high IL-6 and wasting condition2011
- Author(s)
  Mitsunaga S.
- Organizer
  2011 ASCO Annual Meeting
- Place of Presentation
  Chicago, U. S. A.
- Data Source
  KAKENHI-PROJECT-22790624
[Presentation] Neural invasion induces cachexia and pain in pancreatic cancer2011
- Author(s)
  Mitsunaga S.
- Organizer
  6^<th> Cachexia Conference
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-22790624
[Presentation] Clinical significance of the elevation of serum IL-6 level in advanced pancreatic cancer (Abstract No : 181)2011
- Author(s)
  Mitsunaga S
- Organizer
  2011 Gastrointestinal Cancers Symposium
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-22790624
[Presentation] Clinical significance of the elevation of serum IL-6 level in advanced pancreatic cancer2011
- Author(s)
  Mitsunaga S.
- Organizer
  2011 Gastrointestinal Cancers Symposium
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-22790624
[Presentation] 進行膵がんにおいて、病状悪化を認めるIL-6高値群のうちIL-1高値群は予後不良である2011
- Author(s)
  光永修一
- Organizer
  第42回日本膵臓学会大会
- Place of Presentation
  青森
- Year and Date
  2011-07-29
- Data Source
  KAKENHI-PROJECT-22790624
[Presentation] 膵がんにおける抗IL-6療法の意義2011
- Author(s)
  光永修一
- Organizer
  第84回日本内分泌学会学術集会
- Place of Presentation
  日神戸市
- Year and Date
  2011-04-23
- Data Source
  KAKENHI-PROJECT-22790624
[Presentation] Use of elevated IL-1 to predict prognosis in patients with advanced pancreatic cancer with high IL-6 and wasting condition2011
- Author(s)
  S.Mitsunaga
- Organizer
  2011 ASCO Annual Meeting
- Place of Presentation
  Chicago, U.S.A.
- Data Source
  KAKENHI-PROJECT-22790624
[Presentation] 膵がんにおける抗IL-6療法の意義2011
- Author(s)
  光永修一
- Organizer
  第84回日本内分泌学会学術集会
- Place of Presentation
  神戸市
- Year and Date
  2011-04-23
- Data Source
  KAKENHI-PROJECT-22790624
[Presentation] Role of IL-6 in cachexia progression in advanced pancreatic cancer2010
- Author(s)
  Mitsunaga S.
- Organizer
  2010 ASCO Annual Meeting
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-22790624
[Presentation] 進行膵がんにおいて、血中インターロイキン6濃度の経時的上昇は、腫瘍量および悪液質症状の増悪と関連する2010
- Author(s)
  光永修一
- Organizer
  第31回日本臨床薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22790624
[Presentation] Role of IL-6 in cachexia progression in advanced pancreatic cancer. (Abstract No : 4101)2010
- Author(s)
  Mitsunaga S
- Organizer
  2010 ASCO Annual Meeting
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-22790624
[Presentation] Low Level of Circulating IL-6 is Associated with Neutropenia of Gemcitabine in Advanced Pancreatic Cancer.2010
- Author(s)
  Shuichi Mitsunaga
- Organizer
  第14回国際膵臓学会第41回日本膵臓学会大会合同会議
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22790624
[Presentation] Astrocytic activation by neural invasion modulates pain in pancreatic cancer.(膵がん患者の疼痛には神経浸潤に由来する脊髄アストロサイトの活性化が関与する)2010
- Author(s)
  光永修一
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22790624
[Presentation] 進行膵がん患者において、インターロイキン6の血中濃度は、C反応性蛋白、アルブミン、倦怠感と相関する2010
- Author(s)
  光永修一
- Organizer
  第8回日本臨床腫瘍学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22790624
[Presentation] Low Level of Circulating IL-6 is Associated with Neutropenia of Gemcitabine in Advanced Pancreatic Cancer2010
- Author(s)
  Mitsunaga S.
- Organizer
  第14回国際膵臓学会第41回日本膵臓学会大会合同会議
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22790624
[Presentation] Astrocytic activation by neural invasion modulates pain in pancreatic cancer.(膵がん患者の疼痛には神経浸潤に由来する脊髄アストロサイトの活性化が関与する)2010
- Author(s)
  光永修一
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22790624
[Presentation] 2.Loss of STAT3 tyrosine phosphorylation in tumor relates poor prognosis in patients with advanced pancreatic cancer. （English Oral Sessions）
- Author(s)
  Shuichi Mitsunaga
- Organizer
  第12回日本臨床腫瘍学会学術集会
- Place of Presentation
  日本
- Year and Date
  2014-07-17 – 2014-07-19
- Data Source
  KAKENHI-PROJECT-26460930
[Presentation] 4.S100P tumor-marker response to chemotherapy in patients with advanced pancreatic cancer. (general poster session)
- Author(s)
  Shuichi Mitsunaga
- Organizer
  ASCO-GI2015 Gastrointestinal Cancers Symposium
- Place of Presentation
  San Francisco
- Year and Date
  2015-01-15 – 2015-01-17
- Data Source
  KAKENHI-PROJECT-26460930
[Presentation] Nervous system reaction to neural invasion leads to cachexia in pancreatic cancer
- Author(s)
  Shuichi Mitsunaga
- Organizer
  7th cachexia conference（国際悪液質会議）
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-24790669
[Presentation] evere neural invasion related to cachexia in advanced pancreatic cancer.
- Author(s)
  Akira Imoto, Shuichi Mitsunaga
- Organizer
  igestive Disease Week 2014 Chicago
- Place of Presentation
  Chicago
- Year and Date
  2014-05-04 – 2014-05-06
- Data Source
  KAKENHI-PROJECT-26460930
[Presentation] 膵がん神経浸潤モデルによる悪液質解明
- Author(s)
  光永修一
- Organizer
  第7回In vivo実験医学シンポジウム
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-24790669
[Presentation] IL-6/STAT3経路は、膵癌の腫瘍浸潤と疼痛に関与する
- Author(s)
  光永修一
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-24790669

1. Umeda Izumi (40160791)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 藤井博史 (80218982)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 秋元哲夫 (10261851)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 小嶋基寛 (30338470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 近藤俊輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MITSUNAGA Shuichi 光永 修一

光永 修一 ミツナガ シュウイチ

Research Projects

Research Products

Co-Researchers

Development of innovative radionuclide therapy and radio-theranostics for enabling cure of advance solid tumors

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cancer cachexia via cancer-nerve closstalk in pancreatic cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanism of astrocyte-related cachexia and pain due to neural invasion of pancreatic cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Innovation of anti-cachectic therapy with anti-tumor effect for pancreatic cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 肝細胞癌に対するソラフェニブ チームネクサバール-国立がんセンター東病院のチーム医療-2010

Author(s)

Total Pages

Publisher

Data Source

[Book] 膵がん患者の「るいそう」とIL-6、腫瘍内科2010

Author(s)

Publisher

Data Source

[Book] 特集膵・胆道癌における分子標的治療の動向膵癌におけるIL-6の発現と治療応用、胆と膵2010

Author(s)

Publisher

Data Source

[Book] あらゆる病態・症例に対応できる消化器がん化学療法の実践2010

Author(s)

Total Pages

Publisher

Data Source

[Book] 膵がん患者の「るいそう」とIL-6.腫瘍内科2010

Author(s)

Total Pages

Publisher

Data Source

[Book] 特集膵・胆道癌における分子標的治療の動向 膵癌におけるIL-6の発現と治療応用胆と膵2010

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Multicenter, Open-Label, Phase I/II Study of Tocilizumab, an Anti-Interleukin-6 Receptor Monoclonal Antibody, Combined with Gemcitabine in Patients with Advanced Pancreatic Cancer.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] C-Reactive Protein Level Is an Indicator of the Aggressiveness of Advanced Pancreatic Cancer.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characterization of Patients With Advanced Pancreatic Cancer and High Serum Interleukin-6 Levels.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characterization of Patients With Advanced Pancreatic Cancer and High Serum Interleukin-6 Levels.2015

Author(s)

Journal Title

Data Source

[Journal Article] Prognostic impact of M2 macrophages at neural invasion in patients with invasive ductal carcinoma of the pancreas.2014

Author(s)

Journal Title

DOI

MITSUNAGA Shuichi 光永修一

光永修一ミツナガシュウイチ

[Book] 肝細胞癌に対するソラフェニブチームネクサバール-国立がんセンター東病院のチーム医療-2010

[Book] 特集膵・胆道癌における分子標的治療の動向膵癌におけるIL-6の発現と治療応用胆と膵2010