Horibe Tomohisa 堀部智久

… Alternative Names

堀部智久ホリベトモヒサ

HORIBE Tomohisa 堀部智久

Less

Researcher Number	20467468
Other IDs
Affiliation (Current)	2025: 長浜バイオ大学, バイオサイエンス学部, 教授
Affiliation (based on the past Project Information) *help	2023: 長浜バイオ大学, バイオサイエンス学部, 教授 2020 – 2021: 長浜バイオ大学, バイオサイエンス学部, 教授 2017 – 2019: 京都大学, 医学研究科, 特定准教授 2016 – 2017: 京都大学, 大学院医学研究科, 特定准教授 2016: 京都大学, 医学研究科, 特定講師 … More 2014 – 2015: 京都大学, 医学(系)研究科(研究院), 講師 2013: 京都大学, 医学(系)研究科(研究院), 特定講師 2013: 京都大学, 大学院医学研究科, 特定講師 2012: 京都大学, 医学(系)研究科(研究院), 助教 2010: 京都大学, 大学院・医学研究科, 特定助教 Less
Review Section/Research Field	Principal Investigator Biological pharmacy / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Basic Section 50010:Tumor biology-related / Tumor therapeutics Except Principal Investigator Medical pharmacy / Aquatic bioproduction science / Tumor therapeutics / Clinical oncology / Drug development chemistry
Keywords	Principal Investigator 分子シャペロン / タンパク質 / 癌 / 発光イメージング / ケミカルバイオロジー / 薬剤評価 / 生物発光 / 生化学 / ストレス / 薬学 … More Except Principal Investigator … More ペプチド創薬 / ペプチド / 難治性癌 / ハイブリッドペプチド / 分子標的治療 / DDS / 分子標的 / ドラックデリバリー / 経口製剤 / ドラッグデリバリー / 薬物動態学 / 移植 / 緑色蛍光タンパク質 / マダイ / 遺伝子導入 / 顕微注入 / 発光 / ゲノム編集 / GFP / メダカ / ビテロゲニン / デンドリマー / 癌 / 治療抵抗性 / 局所投与 / 医薬分子設計 Less

PDI関連タンパク質の生体内発現機構を指標とした新たな薬剤評価系の構築Principal Investigator
- Principal Investigator
  
  堀部智久
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Nagahama Institute of Bio-Science and Technology
Study on functional roles of P5 in cancer microenvironment based on the interaction of glioblastoma with microglia cellsPrincipal Investigator
- Principal Investigator
  
  Horibe Tomohisa
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Nagahama Institute of Bio-Science and Technology
  Kyoto University
Genome Editing without microinjection into eggs
- Principal Investigator
  
  Kinoshita Masato
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Aquatic bioproduction science
- Research Institution
  Kyoto University
Functional analysis of P5 in glioblastoma cells for new molecular targeted therapyPrincipal Investigator
- Principal Investigator
  
  Horibe Tomohisa
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Kyoto University
Improvement of oral delivery of hybrid peptide using absorption enhancer
- Principal Investigator
  
  Gaowa Arong
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Mie University
  Kyoto University
Functional analysis of protein disulfide isomerase P5 as anti-cancer targetPrincipal Investigator
- Principal Investigator
  
  HORIBE TOMOHISA
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyoto University
Study on new strategy of glioblastoma treatment by molecular targeted anti-cancer hybrid peptide
- Principal Investigator
  
  Kawakami Koji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Kyoto University
Development of novel anticancer drug by functionalized hybrid peptide
- Principal Investigator
  
  Kurihara Ryohsuke
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Aoyama Gakuin University
  Kyoto University
Establishment of evaluation methods for molecular targeted anticancer drugs targeting organelle specific stress response in the cellPrincipal Investigator
- Principal Investigator
  
  HORIBE Tomohisa
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyoto University
Development of cancer treatment by molecular targeted anti-cancer hybrid peptide against refractory cancers which are resistant to cancer chemotherapy
- Principal Investigator
  
  KAWAKAMI Koji
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Clinical oncology
- Research Institution
  Kyoto University
Basic research of new local treatment for inflammatory diseases using molecular-targeting chimera peptide
- Principal Investigator
  
  KOHNO Masayuki
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kyoto University

All 2023 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] Development of an efficient bioreactor system for delivering foreign proteins secreted from liver into eggs with a vitellogenin signal in medaka Oryzias latipes2019
- Author(s)
  Yu Murakami, Tomohisa Horibe, Masato Kinoshita
- Journal Title
  
  Fisheries Science
  
  Volume: 85 Issue: 4 Pages: 677-685
- DOI
  10.1007/s12562-019-01320-4
- NAID
  130007884604
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03860
[Journal Article] Functional analysis of protein disulfide isomerase P5 in glioblastoma cells as a novel anti-cancer target2019
- Author(s)
  Horibe, T., Torisawa, A., Masuda, Y., and Kawakami, K.
- Journal Title
  
  Oncology Rep
  
  Volume: 41 Pages: 961-972
- DOI
  10.3892/or.2018.6868
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07170
[Journal Article] Bile acid as an effective absorption enhancer for oral delivery of epidermal growth factor receptor targeted hybrid peptide2018
- Author(s)
  Gaowa, A., Horibe, T., Kohno, M., Kawakami, K
- Journal Title
  
  J Pharm Sci
  
  Volume: 107 Issue: 5 Pages: 1322-1329
- DOI
  10.1016/j.xphs.2017.12.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K18937
[Journal Article] Development of molecular targeted anti-cancer hybrid peptide for novel cancer therapy2017
- Author(s)
  堀部　智久、河野　雅之、瀬戸　佳穂里、阿栄高娃、川上　浩司
- Journal Title
  
  生化学
  
  Volume: 89 Issue: 1 Pages: 31-38
- DOI
  10.14952/SEIKAGAKU.2017.890031
- ISSN
  0037-1017
- Year and Date
  2017-02-25
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K18937
[Journal Article] Monitoring Bip promoter activation during cancer cell growth by bioluminescence imaging at the single-cell level2015
- Author(s)
  Tomohisa Horibe, Aya Torisawa, Ryohsuke Kurihara, Ryutaro Akiyoshi, Yoko Hatta-Ohashi, Hirobumi Suzuki, Koji Kawakami
- Journal Title
  
  Integrative Cancer Science and Therapeutics
  
  Volume: 2 Issue: 6 Pages: 291-299
- DOI
  10.15761/icst.1000157
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26860103
[Journal Article] Discovery of protein disulfide isomerase P5 inhibitors that reduce the secretion of MICA from cancer cells.2014
- Author(s)
  Horibe T, (他3名)
- Journal Title
  
  ChemBioChem
  
  Volume: 15 Issue: 11 Pages: 1599-1606
- DOI
  10.1002/cbic.201400050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26870287
[Journal Article] Transfection efficiency of normal and cancer cell lines and monitoring of promoter activity by single-cell bioluminescence imaging.2014
- Author(s)
  Horibe, T., （他5名）
- Journal Title
  
  Luminescence
  
  Volume: 29 Issue: 1 Pages: 96-100
- DOI
  10.1002/bio.2508
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790072
[Journal Article] Her2 targeted hybrid peptide that blocks her2 tyrosine kinase disintegrates cancer cell membrane and inhibits tumor growth in vivo2013
- Author(s)
  Kawamoto, M., Horibe, T., Kohno, M., and Kawakami, K
- Journal Title
  
  Mol Cancer Ther
  
  Volume: 12 Issue: 4 Pages: 384-393
- DOI
  10.1158/1535-7163.mct-12-0357
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23680089
[Journal Article] Immunogenicity and toxicity of transferring receptor-targeted hybrid peptide as a potent anticancer agent2013
- Author(s)
  Kawamoto, M., Kohno, M., Horibe, T., and Kawakami, K
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 71 Issue: 3 Pages: 799-807
- DOI
  10.1007/s00280-013-2074-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23680089
[Journal Article] Molecular mechanism of cytotoxicity induced by Hsp90-targeted Antp-TPR hybrid peptide in glioblastoma cells.2012
- Author(s)
  Horibe T, （他2名）, and Kawakami K.
- Journal Title
  
  Molecular Cancer
  
  Volume: 11 Issue: 1 Pages: 59-59
- DOI
  10.1186/1476-4598-11-59
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23680089, KAKENHI-PROJECT-24790072
[Journal Article] Cytotoxic activity to acute myeloid leukemia cells by Antp-TPR hybrid peptide targeting Hsp90.2012
- Author(s)
  Horibe T, （他2名）, and Kawakami K.
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 114 Issue: 1 Pages: 96-103
- DOI
  10.1016/j.jbiosc.2012.02.016
- NAID
  110009479373
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23680089
[Journal Article] Targeting interleukin-4 receptor alpha with hybrid peptide for effective cancer therapy2012
- Author(s)
  Yang, L., Horibe, T., Kohno, M., Haramoto, M., Ohara, K., Puri, R., and Kawakami, K
- Journal Title
  
  Mol Can Ther
  
  Volume: 11 Issue: 1 Pages: 235-243
- DOI
  10.1158/1535-7163.mct-11-0363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23680089
[Journal Article] Semaphorin 3A-lytic hybrid peptide binding to neuropillin-1 as a novel anti-cancer agent in pancreatic cancer2011
- Author(s)
  Ueyama, H., Horibe, T., Nakajima, O., Ohara, K., Kohno, M., and Kawakami, K
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 414 Issue: 1 Pages: 60-66
- DOI
  10.1016/j.bbrc.2011.09.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23680089
[Journal Article] A novel Transferrin-receptor-targeted hybrid peptide permeates the cancer cell membrane to induce rapid killing of cancer cells2011
- Author(s)
  Kawamoto, M., Horibe, T., Kohno, M., and Kawakami, K
- Journal Title
  
  BMC cancer
  
  Volume: 11 Issue: 1 Pages: 359-359
- DOI
  10.1186/1471-2407-11-359
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23680089
[Journal Article] A novel hybrid peptide targeting EGFR-expressing cancers.2011
- Author(s)
  Kohno M, Horibe T, Haramoto M, Yano Y, Ohara K, Nakajima O, Matsuzaki K, Kawakami K.
- Journal Title
  
  Eur J Cancer. 47
  
  Pages: 773-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790111
[Presentation] fLuc-GFPノックインメダカを用いたprotein disulfide isomerase P5/PDIA6の発生段階および成魚における発現様式の解析2023
- Author(s)
  伊藤啓輔、佐藤夏美、植田華、村上悠、木下政人、堀部智久
- Organizer
  第96回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-23K06143
[Presentation] fLuc-GFPノックインメダカを用いたtransmembrane oxidoreductase (TMX1/PDIA11)の生体内発現機構の解析2023
- Author(s)
  河野有紀、植田華、佐藤夏美、村上悠、木下政人、堀部智久
- Organizer
  第96回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-23K06143
[Presentation] Functional analysis of protein disulfide isomerase P5 in glioblastoma cells by bioluminescence imaging method at single cell level2019
- Author(s)
  Horibe, T. and Kawakami, K.
- Organizer
  COMBIO 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07170
[Presentation] Functional analysis of novel interleukin-13 receptorα2-targeted hybrid peptide for potent glioblastoma therapy2019
- Author(s)
  Horibe, T. and Kawakami, K.
- Organizer
  第78回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07638
[Presentation] 卵内物質輸送を可能とするモデルメダカの作出2018
- Author(s)
  村上悠、堀部智久、木下政人
- Organizer
  平成３０年度日本水産学会秋季大会
- Data Source
  KAKENHI-PROJECT-17H03860
[Presentation] Improvement of oral delivery of EGFR-targeted hybrid peptide by combination with bile acid.2017
- Author(s)
  Gaowa. A., Horibe, T., Kohno, M., and Kawakami, K.
- Organizer
  The 12th Australian Peptide Conference
- Data Source
  KAKENHI-PROJECT-16K18937
[Presentation] Functional analysis of protein disulfide isomerase P5 in glioblastoma cells as a potent anti-cancer target2016
- Author(s)
  Horibe T and Kawakami K.
- Organizer
  第75回日本癌学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K07170
[Presentation] 難治性がんを標的としたハイブリッドペプチドによるペプチド抗がん剤の開発2016
- Author(s)
  栗原亮介、堀部智久、河野雅之、田邉一仁、川上浩司
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  同志社大学　京田辺キャンパス
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-26860103
[Presentation] Functional analysis of protein disulfide isomerase P5 in cancer cells by simultaneous observation method of both bioluminescence and fluorescence imaging at single cell level2015
- Author(s)
  Horibe T, (他2名)
- Organizer
  World Molecular Imaging Congress (WMIC) 2015
- Place of Presentation
  Honolulu, USA
- Year and Date
  2015-09-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870287
[Presentation] Functional analysis of protein disulfide isomerase P5 as a potent anti-cancer target2015
- Author(s)
  Horibe T and Kwakami K.
- Organizer
  第74回日本癌学会学術集会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26870287
[Presentation] P5活性阻害剤のスクリーニングおよび癌細胞からのMICAの分泌に与える影響2015
- Author(s)
  堀部智久、(他2名)
- Organizer
  第62回日本生化学会　近畿支部例会
- Place of Presentation
  立命館大学びわこ・くさつキャンパス
- Year and Date
  2015-05-16
- Data Source
  KAKENHI-PROJECT-26870287
[Presentation] 癌細胞からのMICA分泌を減少させるP5活性阻害剤のスクリーニング2014
- Author(s)
  堀部　智久
- Organizer
  第１回　バイオ・フロンティア・プラットフォームシンポジウム
- Place of Presentation
  京都大学　医学部・記念講堂
- Year and Date
  2014-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-26870287
[Presentation] Novel Her2-targeted hybrid peptide that disintegrates cancer cell membrane and inhibits tumor growth in vivo.2013
- Author(s)
  Horibe, T., （他3名）
- Organizer
  第72回日本癌学会学術集会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24790072
[Presentation] Novel Her2-targeted hybrid peptide that disintegrates cancer cell membrane and inhibits tumor growth in vivo.2013
- Author(s)
  Horibe, T., （他2名）, and Kawakami, K.
- Organizer
  第72回日本癌学会学術集会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23680089
[Presentation] Functional analysis of cytotoxic activity to glioblastoma cells by Antp-TPR hybrid peptide targeting Hsp90.2013
- Author(s)
  Horibe, T. and Kawakami, K.
- Organizer
  第17回日本がん分子標的治療学会学術集会
- Place of Presentation
  京都国際会館
- Data Source
  KAKENHI-PROJECT-24790072
[Presentation] Functional analysis of cytotoxic activity to glioblastoma cells by Antp-TPR hybrid peptide targeting Hsp90.2013
- Author(s)
  Horibe, T. and Kawakami, K.
- Organizer
  第17回日本がん分子標的治療学会学術集会
- Place of Presentation
  京都国際会館
- Data Source
  KAKENHI-PROJECT-23680089
[Presentation] Functional analysis of cytotoxic activity to glioblastoma cells by Antp-TPR hybrid peptide targeting Hsp902013
- Author(s)
  Horibe, T. and Kawakami, K
- Organizer
  第17回日本がん分子標的治療学会
- Place of Presentation
  京都国際会館
- Data Source
  KAKENHI-PROJECT-23680089
[Presentation] Confirmation of transfection efficiency for normal and cancer cell lines and monitoring of promoter activity by bioluminescence imaging at single cell level2013
- Author(s)
  Torisawa, A., Horibe, T., Akiyoshi, R., Hatta-Ohashi, Y., Suzuki, H., and Kawakami, K
- Organizer
  第86回日本生化学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23680089
[Presentation] Novel Her2-targeted hybrid peptide that disintegrates cancer cell membrane and inhibits tumor growth in vivo2013
- Author(s)
  Horibe, T., Kawamoto, M., Kohno, M., and Kawakami, K
- Organizer
  第72回日本癌学会学術集会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23680089
[Presentation] Increase of cytotoxic activity induced by Antp-TPR hybrid peptide in the presence of Hsp70-targeted peptide to breast cancer cells2013
- Author(s)
  Horibe, T., Torisawa, A., Kohno, M., and Kawakami, K
- Organizer
  第86回日本生化学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24790072
[Presentation] Functional analysis of cytotoxic activity to glioblastoma cells by Antp-TPR hybrid peptide targeting Hsp902013
- Author(s)
  Horibe, T. and Kawakami, K
- Organizer
  第17回日本がん分子標的治療学会
- Place of Presentation
  京都国際会館
- Data Source
  KAKENHI-PROJECT-24790072
[Presentation] Increase of cytotoxic activity induced by Antp-TPR hybrid peptide in the presence of Hsp70-targeted peptide to breast cancer cells.2013
- Author(s)
  Horibe, T., （他3名）
- Organizer
  第86回日本生化学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24790072
[Presentation] Functional analysis of cytotoxic activity to acute myeloid leukemia cells by Antp-TPR hybrid peptide targeting Hsp90.2012
- Author(s)
  Horibe T, （他2名）, and Kawakami K.
- Organizer
  第49回ペプチド討論会
- Place of Presentation
  鹿児島県民交流センター
- Data Source
  KAKENHI-PROJECT-23680089
[Presentation] Molecular mechanism of cancer cell death by Antp-TPR hybrid peptide targeting Hsp90 in glioblastoma cells.2012
- Author(s)
  Horibe T, （他3名）
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-24790072
[Presentation] Functional analysis of cytotoxic activity to acute myeloid leukemia cells by Antp-TPR hybrid peptide targeting Hsp90.2012
- Author(s)
  Horibe T, （他3名）
- Organizer
  第49回ペプチド討論会
- Place of Presentation
  鹿児島県民交流センター
- Data Source
  KAKENHI-PROJECT-24790072
[Presentation] Molecular mechanism of cancer cell death by Antp-TPR hybrid peptide targeting Hsp90 in glioblastoma cells.2012
- Author(s)
  Horibe T, （他2名）, and Kawakami K.
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-23680089
[Presentation] Molecular mechanism of cancer cell death by Antp-TPR hybrid peptide targeting Hsp90 in glioblastoma cells2012
- Author(s)
  Horibe, T., Torisawa, A., Kohno, M., and Kawakami, K
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-24790072
[Presentation] Functional analysis of cytotoxic activity to acute myeloid leukemia cells by Antp-TPR hybrid peptide targeting Hsp902012
- Author(s)
  Horibe, T., Kawamoto, M., Kohno, M., and Kawakami, K
- Organizer
  第49回ペプチド討論会
- Place of Presentation
  鹿児島県民交流センター
- Data Source
  KAKENHI-PROJECT-24790072
[Presentation] Hsp90をターゲットにしたAntp-TPRハイブリッドペプチドによる血液癌細胞株に対する殺細胞効果2011
- Author(s)
  堀部智久, 他2名、川上浩司
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23680089
[Presentation] Anti-leukemic activity of hybrid Antp-TPR peptide targeting Hsp902011
- Author(s)
  Horibe, T., Kawamoto, M., Kohno, M., and Kawakami, K
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23680089
[Presentation] Mechanism of cancer cell death by hybrid Antp-TPR peptide targeting Hsp902011
- Author(s)
  Horibe T, 他3名, Kawakami K
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都国際会議場
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-23680089
[Presentation] Mechanism of cancer cell death by hybrid Antp-TPR peptide targeting Hsp902011
- Author(s)
  Horibe, T., Kohno, M., Haramoto, M., Ohara, K., and Kawakami, K
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都国際会館
- Data Source
  KAKENHI-PROJECT-23680089
[Presentation] Enhancement of anticancer activity by the single amino acid conversion of EGFR-binding peptide2011
- Author(s)
  Tada, N., Horibe, T., Haramoto, M., Ohara, K., Kohno, M., and Kawakami, K
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都国際会館
- Data Source
  KAKENHI-PROJECT-23680089
[Presentation] A novel EGFR-targeted hybrid peptide can overcome the resistance of cancer cells to tyrosine kinase inhibitors.2010
- Author(s)
  Masayuki Kohno, Tomohisa Horibe, Yoshiaki Yano, Katsumi Matsuzaki, Koji Kawakami.
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-21790111
[Presentation] Screening and identification of protein disulfide isomerase P5 inhibitors which reduce the secretion of MICA.
- Author(s)
  Horibe T and Kawakami K
- Organizer
  第73回日本癌学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26870287

1. KOHNO Masayuki (00437203)

# of Collaborated Projects: 4 results

# of Collaborated Products: 13 results
2. ARONGGAOWA (50643805)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. KURIHARA RYOUSUKE (20713233)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. KAWAKAMI Koji (70422318)

# of Collaborated Projects: 2 results

# of Collaborated Products: 19 results
5. SETO KAHORI (20737019)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Kinoshita Masato (60263125)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 鷲尾洋平 (60771681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 家戸敬太郎 (90330240)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 有馬祐介 (90402792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Horibe Tomohisa 堀部 智久

堀部 智久 ホリベ トモヒサ

HORIBE Tomohisa 堀部 智久

Research Projects

Research Products

Co-Researchers

PDI関連タンパク質の生体内発現機構を指標とした新たな薬剤評価系の構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on functional roles of P5 in cancer microenvironment based on the interaction of glioblastoma with microglia cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Genome Editing without microinjection into eggs

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of P5 in glioblastoma cells for new molecular targeted therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Improvement of oral delivery of hybrid peptide using absorption enhancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of protein disulfide isomerase P5 as anti-cancer targetPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on new strategy of glioblastoma treatment by molecular targeted anti-cancer hybrid peptide

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel anticancer drug by functionalized hybrid peptide

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of evaluation methods for molecular targeted anticancer drugs targeting organelle specific stress response in the cellPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of cancer treatment by molecular targeted anti-cancer hybrid peptide against refractory cancers which are resistant to cancer chemotherapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic research of new local treatment for inflammatory diseases using molecular-targeting chimera peptide

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Development of an efficient bioreactor system for delivering foreign proteins secreted from liver into eggs with a vitellogenin signal in medaka Oryzias latipes2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Functional analysis of protein disulfide isomerase P5 in glioblastoma cells as a novel anti-cancer target2019

Author(s)

Horibe Tomohisa 堀部智久

堀部智久ホリベトモヒサ

HORIBE Tomohisa 堀部智久