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Ohgaki Ryuichi  大垣 隆一

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OHGAKI Ryuichi  大垣 隆一

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Researcher Number 20467525
Other IDs
Affiliation (Current) 2025: 大阪大学, 大学院医学系研究科, 准教授
Affiliation (based on the past Project Information) *help 2022 – 2025: 大阪大学, 大学院医学系研究科, 准教授
2020 – 2021: 大阪大学, 医学系研究科, 准教授
2016 – 2020: 大阪大学, 医学系研究科, 助教
2011 – 2015: 大阪大学, 医学(系)研究科(研究院), 助教
2014: 大阪大学, 大学院医学系研究科, 助教 … More
2009 – 2013: 大阪大学, 医学系研究科, 助教
2012: 大阪大学, 医学研究科, 助教
2011 – 2012: 大阪大学, 大学院・医学系研究科, 助教
2009: 大阪大学, 大学院・医学系研究科, 助教 Less
Review Section/Research Field
Principal Investigator
Basic Section 48030:Pharmacology-related / General medical chemistry / Basic Section 48040:Medical biochemistry-related / Dermatology
Except Principal Investigator
General pharmacology / Kidney internal medicine / Basic Section 48030:Pharmacology-related / Medium-sized Section 48:Biomedical structure and function and related fields / General medical chemistry / Functional biochemistry / Biological Sciences
Keywords
Principal Investigator
細胞内シグナル伝達 / アミノ酸トランスポーター / 腫瘍血管新生 / シグナル伝達 / mTORC1 / アミノ酸 / 脂質代謝 / 表皮バリア / リパーゼ / 血管新生阻害療法 … More / VEGF-A / 抗腫瘍薬 / 内皮細胞 / 抗悪性腫瘍薬 / 血管内皮細胞 / LAT1 / トランスポーター / 受容体 / 皮膚生理 / 組織形成 / 生体分子医学 / 脂質代謝異常 / 角質細胞間脂質 … More
Except Principal Investigator
トランスポーター / 受容体 / アミノ酸 / 輸送系 / チャネル / シグナル情報伝達系 / 輸送体 / シグナル情報伝達 / プロテオミクス / アミノ酸トランスポーター / 抗腫瘍薬 / 細胞代謝制御 / リン酸化プロテオミクス / 腎臓 / 生体膜 / 細胞休眠化 / 細胞周期 / アミノ酸トランスポータ / 細胞内代謝制御 / 寿命 / 代謝制御・細胞機能制御 / 輸送体介在シグナル / 腫瘍血管新生 / がん / シグナル伝達系 / リピドミクス / リパーゼ / 角質細胞間脂質ラメラ / 表皮バリア / 糖 / 腎近位尿細管 / マルチオミクス / メタボロミクス / 膜輸送複合体 / 比較定量プロテオミクス / 膜複合体 / 機能共役 / 再構成系 / ヘテロ二量体 / ヘテロダイマー / シスチン尿症 / 腎生理 / 腎生理学 / 腎臓学 / 細胞膜 / リン酸化 / 細胞増殖 / レニン / 傍糸球体装置 / 近位尿細管 / プロスタグランジン / 膜イオン輸送 / 細胞極性形成 / 細胞内小胞pH測定 / 蛋白質の局在化機構 / 細胞内小胞輸送機構 / pH調節 / オルガネラ局在 / Na+/H+交換輸送蛋白質 / 細胞内イオン環境 / NHE / 膜小胞輸送 / pH制御 / 生体膜イオン輸送 / Na^+/H^+交換輸送体 / 細胞内蛋白質局在化機構 / 細胞内局所pH制御 / 酵母のNHE / 細胞内小胞型NHE / Na+/H+交換輸送体 / 細胞内pH調節 / 細胞内蛋白質の輸送 / 細胞内小胞型 NHE / 細胞内 pH 調節 Na+/H+ 交換輸送体 / 細胞内蛋白質局在化 機構 / 細胞内局所p H 制御 / 酵母の NHE / エンドサイトーシス / 腎 / 蛋白質間相互作用 / PDZタンパク質 / 上皮輸送 / 複合体 / 膜輸送 Less
  • Research Projects

    (21 results)
  • Research Products

    (319 results)
  • Co-Researchers

    (24 People)
  •  細胞内遊離アミノ酸の変動に基づくアミノ酸輸送体阻害薬の抗腫瘍効果の実体解明Principal Investigator

    • Principal Investigator
      大垣 隆一
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48030:Pharmacology-related
    • Research Institution
      The University of Osaka
  •  腫瘍血管新生におけるアミノ酸輸送体LAT1とVEGF-Aの協調的機能の解明Principal Investigator

    • Principal Investigator
      大垣 隆一
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48030:Pharmacology-related
    • Research Institution
      Osaka University
  •  Elucidation of the transmembrane signal mechanism responsible for metabolic control by amino acid availability

    • Principal Investigator
      Kanai Yoshikatsu
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 48:Biomedical structure and function and related fields
    • Research Institution
      Osaka University
  •  がん細胞アミノ酸輸送体阻害薬の強力な細胞周期制御の機序と細胞休眠化機構の解明

    • Principal Investigator
      金井 好克
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48030:Pharmacology-related
    • Research Institution
      Osaka University
  •  Study on the amino acid signaling via transporters and receptors for the pharmacologic control of cellular metabolism

    • Principal Investigator
      Kanai Yoshikatsu
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48030:Pharmacology-related
    • Research Institution
      Osaka University
  •  Amino acid signaling in the downstream of endothelially expressed amino acid transporter LAT1 that contributes to tumor angiogenesisPrincipal Investigator

    • Principal Investigator
      Ohgaki Ryuichi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Osaka University
  •  Study on the effects of amino acid availability on life span and the underlying molecular mechanisms

    • Principal Investigator
      Kanai Yoshikatsu
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 48:Biomedical structure and function and related fields
    • Research Institution
      Osaka University
  •  Molecular identification of amino acid sensor and its function in mTORC1 signaling pathwayPrincipal Investigator

    • Principal Investigator
      Ohgaki Ryuichi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Osaka University
  •  The function of a novel membrane protein in renal proximal tubules

    • Principal Investigator
      Nagamori Shushi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Nara Medical University
      Osaka University
  •  Investigation of a novel lipase-like transmembrane protein for the discovery of drugs to regulate the epidermal barrier function

    • Principal Investigator
      Kanai Yoshikatsu
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General pharmacology
    • Research Institution
      Osaka University
  •  Regulation of cellular metabolism and functions mediated by amino acid transporters and the mechanisms of action of their inhibitors

    • Principal Investigator
      KANAI Yoshikatsu
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Osaka University
  •  Identification of a Vesicle specific D-serine transporter in the brain.

    • Principal Investigator
      YOSHIKATSU Kanai
    • Project Period (FY)
      2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General pharmacology
    • Research Institution
      Osaka University
  •  Lipid metabolism in stratum corneum essential for the maintenace of intercellular ceramides mediated by a novel transmembrane lipasePrincipal Investigator

    • Principal Investigator
      OHGAKI Ryuichi
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Dermatology
    • Research Institution
      Osaka University
  •  Identification and characterization of a membrane protein TRAP involved in Fanconi syndrome like symptoms.

    • Principal Investigator
      Kanai Yoshikatsu
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Osaka University
  •  Identification and the physiological role of a cystine transporter

    • Principal Investigator
      NAGAMORI Shushi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Osaka University
  •  Identification of plasma membrane leucine receptor and elucidation of its link to mTOR signaling pathway

    • Principal Investigator
      KANAI Yoshikatsu
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General pharmacology
    • Research Institution
      Osaka University
  •  Function of a novel ER-localized transmembrane lipase-like protein in epidermal barrier formationPrincipal Investigator

    • Principal Investigator
      OHGAKI Ryuichi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Osaka University
  •  Signaling mechanisms of a novel-type transmembrane receptor 4F2hc

    • Principal Investigator
      KANAI Yoshikatsu
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General pharmacology
    • Research Institution
      Osaka University
  •  pH regulation of organelles and its physiological role and molecular mechanism

    • Principal Investigator
      KANAZAWA Hiroshi
    • Project Period (FY)
      2009 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      Chugoku Gakuen University
      Osaka University
  •  Roles of a novel kidney-specific prostaglandin(PG) transporter in local PG clearance in renal cortex and its pathological relevance

    • Principal Investigator
      KANAI Yoshikatsu
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Osaka University
  •  Organic solute transportsomes: their molecular assembly and functional significance

    • Principal Investigator
      KANAI Yoshikatsu
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
      Kyorin University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Patent

  • [Journal Article] Inhibition of amino acid transporter LAT1 in cancer cells suppresses G0/G1-S transition by downregulating cyclin D1 via p38 MAPK activation2024

    • Author(s)
      Zhou Xinyu、Ohgaki Ryuichi、Jin Chunhuan、Xu Minhui、Okanishi Hiroki、Endou Hitoshi、Kanai Yoshikatsu
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 154 Issue: 3 Pages: 182-191

    • DOI

      10.1016/j.jphs.2024.01.007

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K19451, KAKENHI-PROJECT-22K06856, KAKENHI-PROJECT-22K19404, KAKENHI-PROJECT-21K20742, KAKENHI-PROJECT-23K24071
  • [Journal Article] Structure activity characteristics of phenylalanine analogs selectively transported by L-type amino acid transporter 1 (LAT1)2024

    • Author(s)
      Chen Sihui、Jin Chunhuan、Ohgaki Ryuichi、Xu Minhui、Okanishi Hiroki、Kanai Yoshikatsu
    • Journal Title

      Scientific Reports

      Volume: 14 Issue: 1 Pages: 1-13

    • DOI

      10.1038/s41598-024-55252-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K19451, KAKENHI-PROJECT-22K06856, KAKENHI-PROJECT-22K19404, KAKENHI-PROJECT-21K20742, KAKENHI-PROJECT-23K24071
  • [Journal Article] Identification of tumor-suppressive miRNAs that target amino acid transporter LAT1 and exhibit anti-proliferative effects on cholangiocarcinoma cells2024

    • Author(s)
      Liu Xingming、Nishikubo Kou、Ohgaki Ryuichi、Okanishi Hiroki、Okuda Suguru、Xu Minhui、Kanai Yoshikatsu
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: - Issue: 4 Pages: 301-311

    • DOI

      10.1016/j.jphs.2024.02.012

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06856, KAKENHI-PROJECT-22K19404, KAKENHI-PROJECT-21K20742, KAKENHI-PROJECT-22KJ2171, KAKENHI-PROJECT-23K24071
  • [Journal Article] Upregulation of ATF4 mediates the cellular adaptation to pharmacologic inhibition of amino acid transporter LAT1 in pancreatic ductal adenocarcinoma cells2024

    • Author(s)
      Ma Yu、Okuda Suguru、Okanishi Hiroki、Xu Minhui、Jin Chunhuan、Endou Hitoshi、Ohgaki Ryuichi、Kanai Yoshikatsu
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 155 Issue: 1 Pages: 14-20

    • DOI

      10.1016/j.jphs.2024.03.001

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K19451, KAKENHI-PROJECT-22K06856, KAKENHI-PROJECT-22K19404, KAKENHI-PROJECT-21K20742, KAKENHI-PROJECT-23K24071
  • [Journal Article] Inhibition of cancer-type amino acid transporter LAT1 suppresses B16-F10 melanoma metastasis in mouse models2023

    • Author(s)
      Shi Zitong、Kaneda-Nakashima Kazuko、Ohgaki Ryuichi、Xu Minhui、Okanishi Hiroki、Endou Hitoshi、Nagamori Shushi、Kanai Yoshikatsu
    • Journal Title

      Scientific Reports

      Volume: 13 Issue: 1 Pages: 13943-13943

    • DOI

      10.1038/s41598-023-41096-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06856, KAKENHI-PROJECT-21K07619, KAKENHI-PROJECT-22K19404, KAKENHI-PROJECT-21K20742, KAKENHI-PROJECT-21H03365, KAKENHI-PROJECT-23K24071
  • [Journal Article] Combination effects of amino acid transporter LAT1 inhibitor nanvuranlat and cytotoxic anticancer drug gemcitabine on pancreatic and biliary tract cancer cells2023

    • Author(s)
      Nishikubo Kou、Ohgaki Ryuichi、Liu Xingming、Okanishi Hiroki、Xu Minhui、Endou Hitoshi、Kanai Yoshikatsu
    • Journal Title

      Cancer Cell International

      Volume: 23 Issue: 1 Pages: 116-116

    • DOI

      10.1186/s12935-023-02957-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06856, KAKENHI-PROJECT-22K19404, KAKENHI-PROJECT-21K20742, KAKENHI-PROJECT-22KJ2171, KAKENHI-PROJECT-23K24071
  • [Journal Article] Evaluation of LAT1 Expression in Patients With Lung Cancer and Mediastinal Tumors2023

    • Author(s)
      Watabe Tadashi、Ose Naoko、Naka Sadahiro、Fukui Eriko、Kimura Toru、Kanou Takashi、Funaki Soichiro、Sasaki Hidetaka、Kamiya Takashi、Kurimoto Kenta、Isohashi Kayako、Tatsumi Mitsuaki、Shimosegawa Eku、Kato Hiroki、Ohgaki Ryuichi、Kanai Yoshikatsu、Shintani Yasushi
    • Journal Title

      Clinical Nuclear Medicine

      Volume: 48 Issue: 10 Pages: 853-860

    • DOI

      10.1097/rlu.0000000000004816

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06856, KAKENHI-PROJECT-22K07706, KAKENHI-PROJECT-22K19404, KAKENHI-PROJECT-23K24071
  • [Journal Article] The Clinical Potential of FBPA-PET/CT Imaging for Colorectal Cancer and its Liver Metastases Expressing LAT12023

    • Author(s)
      MINOJI TAKAYUKI、TAKAHASHI HIDEKAZU、WATABE TADASHI、ISHIKAWA SATOSHI、KATO HIROKI、OHGAKI RYUICHI、KANAI YOSHIKATSU、SEKIDO YUKI、HATA TSUYOSHI、HAMABE ATSUSHI、OGINO TAKAYUKI、MIYOSHI NORIKATSU、UEMURA MAMORU、YAMAMOTO HIROFUMI、DOKI YUICHIRO、EGUCHI HIDETOSHI
    • Journal Title

      Anticancer Research

      Volume: 43 Issue: 9 Pages: 3913-3921

    • DOI

      10.21873/anticanres.16579

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K06856, KAKENHI-PROJECT-23K08128, KAKENHI-PROJECT-22K19404, KAKENHI-PROJECT-23K24071
  • [Journal Article] LAT1 expression influences Paneth cell number and tumor development in ApcMin/+ mice2023

    • Author(s)
      Yunlong Sui, Namiko Hoshi, Ryuichi Ohgaki, Ryutaro Yoshida, Yuzo Kodama, et al.
    • Journal Title

      Journal of Gastroenterology

      Volume: 58 Issue: 5 Pages: 444-457

    • DOI

      10.1007/s00535-023-01960-5

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K16795, KAKENHI-PROJECT-22K06856, KAKENHI-PROJECT-22K19404, KAKENHI-PROJECT-22K19458, KAKENHI-PROJECT-21H04807, KAKENHI-PROJECT-23K24071
  • [Journal Article] Pharmacologic inhibition of LAT1 predominantly suppresses transport of large neutral amino acids and downregulates global translation in cancer cells2022

    • Author(s)
      Nishikubo Kou、Ohgaki Ryuichi、Okanishi Hiroki、Okuda Suguru、Xu Minhui、Endou Hitoshi、Kanai Yoshikatsu
    • Journal Title

      Journal of Cellular and Molecular Medicine

      Volume: 26 Issue: 20 Pages: 5246-5256

    • DOI

      10.1111/jcmm.17553

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06856, KAKENHI-PROJECT-22K19404, KAKENHI-PROJECT-21K20742, KAKENHI-PROJECT-22KJ2171, KAKENHI-PROJECT-20K07327, KAKENHI-PROJECT-23K24071
  • [Journal Article] アミノ酸トランスポーター阻害薬によるがん治療 -研究の展開と解明が進むユニークな抗腫瘍効果の発現機序-2022

    • Author(s)
      大垣隆一
    • Journal Title

      日本応用酵素協会誌

      Volume: 56 Pages: 21-28

    • Data Source
      KAKENHI-PROJECT-19H03407
  • [Journal Article] Phosphoproteomics revealed cellular signals immediately responding to disruption of cancer amino acid homeostasis induced by inhibition of l-type amino acid transporter 12022

    • Author(s)
      Okanishi Hiroki、Ohgaki Ryuichi、Xu Minhui、Endou Hitoshi、Kanai Yoshikatsu
    • Journal Title

      Cancer & Metabolism

      Volume: 10 Issue: 1 Pages: 18-18

    • DOI

      10.1186/s40170-022-00295-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06856, KAKENHI-PROJECT-22K19404, KAKENHI-PROJECT-21K20742, KAKENHI-PROJECT-23K24071
  • [Journal Article] Structural insights into inhibitory mechanism of human excitatory amino acid transporter EAAT22022

    • Author(s)
      Kato Takafumi、Kusakizako Tsukasa、Jin Chunhuan、Zhou Xinyu、Ohgaki Ryuichi、Quan LiLi、Xu Minhui、Okuda Suguru、Kobayashi Kan、Yamashita Keitaro、Nishizawa Tomohiro、Kanai Yoshikatsu、Nureki Osamu
    • Journal Title

      Nature Communications

      Volume: 13 Issue: 1 Pages: 4714-4714

    • DOI

      10.1038/s41467-022-32442-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K19404, KAKENHI-PROJECT-22K15072, KAKENHI-PROJECT-21K20742, KAKENHI-PROJECT-20H03216, KAKENHI-PROJECT-20K07327, KAKENHI-PROJECT-20K15754, KAKENHI-PROJECT-21H05037, KAKENHI-PROJECT-23K24071
  • [Journal Article] Functional coupling of organic anion transporter OAT10 (SLC22A13) and monocarboxylate transporter MCT1 (SLC16A1) influencing the transport function of OAT102022

    • Author(s)
      Ohtsu Naoko、Ohgaki Ryuichi、Jin Chunhuan、Xu Minhui、Okanishi Hiroki、Takahashi Ryo、Matsui Akiko、Kishimoto Wataru、Ishiguro Naoki、Kanai Yoshikatsu
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 150 Issue: 1 Pages: 41-48

    • DOI

      10.1016/j.jphs.2022.06.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K19404, KAKENHI-PROJECT-21K20742, KAKENHI-PROJECT-23K24071
  • [Journal Article] Proteomics and phosphoproteomics reveal key regulators associated with cytostatic effect of amino acid transporter LAT1 inhibitor2020

    • Author(s)
      Okanishi Hiroki、Ohgaki Ryuichi、Okuda Suguru、Endou Hitoshi、Kanai Yoshikatsu
    • Journal Title

      Cancer Science

      Volume: 112 Issue: 2 Pages: 871-883

    • DOI

      10.1111/cas.14756

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07327, KAKENHI-PROJECT-19H03407, KAKENHI-PROJECT-18K06931, KAKENHI-PROJECT-19K16743
  • [Journal Article] Interaction of Halogenated Tyrosine/Phenylalanine Derivatives with Organic Anion Transporter 1 in the Renal Handling of Tumor Imaging Probes2020

    • Author(s)
      Jin Chunhuan、Wei Ling、Ohgaki Ryuichi、Tominaga Hideyuki、Xu Minhui、Okuda Suguru、Okanishi Hiroki、Kawamoto Yasuharu、He Xin、Nagamori Shushi、Kanai Yoshikatsu
    • Journal Title

      Journal of Pharmacology and Experimental Therapeutics

      Volume: 375 Issue: 3 Pages: 451-462

    • DOI

      10.1124/jpet.120.000235

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07327, KAKENHI-PROJECT-19H03407, KAKENHI-PROJECT-18K06931, KAKENHI-PROJECT-19H05648
  • [Journal Article] Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation2020

    • Author(s)
      Quan Lili、Ohgaki Ryuichi、Hara Saori、Okuda Suguru、Wei Ling、Okanishi Hiroki、Nagamori Shushi、Endou Hitoshi、Kanai Yoshikatsu
    • Journal Title

      Journal of Experimental & Clinical Cancer Research

      Volume: 39 Issue: 1 Pages: 266-266

    • DOI

      10.1186/s13046-020-01762-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07327, KAKENHI-PROJECT-19H03407, KAKENHI-PROJECT-18K06931, KAKENHI-PROJECT-19H05648
  • [Journal Article] Boron delivery for boron neutron capture therapy targeting a cancer-upregulated oligopeptide transporter2019

    • Author(s)
      Miyabe Junji、Ohgaki Ryuichi、Saito Keijiro、Wei Ling、Quan Lili、Jin Chunhuan、Liu Xingming、Okuda Suguru、Nagamori Shushi、Ohki Hiroshi、Yoshino Kazuo、Inohara Hidenori、Kanai Yoshikatsu
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 139 Issue: 3 Pages: 215-222

    • DOI

      10.1016/j.jphs.2019.01.012

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19429, KAKENHI-PROJECT-16K19018
  • [Journal Article] 【最先端プローブによる細胞外微小環境のシグナル計測】PEG結合リン脂質の細胞外表層pHイメージングへの応用 細胞膜アンカー型プローブ骨格としての可能性2019

    • Author(s)
      大垣 隆一, 寺村 裕治, 林 大智, 永森 收志, 高井 まどか, 金井 好克
    • Journal Title

      日本薬理学雑誌

      Volume: 153 Pages: 254-260

    • Data Source
      KAKENHI-PROJECT-18K19429
  • [Journal Article] Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc2019

    • Author(s)
      Lee Yongchan、Wiriyasermkul Pattama、Jin Chunhuan、Quan Lili、Ohgaki Ryuichi、Okuda Suguru、Kusakizako Tsukasa、Nishizawa Tomohiro、Oda Kazumasa、Ishitani Ryuichiro、Yokoyama Takeshi、Nakane Takanori、Shirouzu Mikako、Endou Hitoshi、Nagamori Shushi、Kanai Yoshikatsu、Nureki Osamu
    • Journal Title

      Nature Structural & Molecular Biology

      Volume: 26 Issue: 6 Pages: 510-517

    • DOI

      10.1038/s41594-019-0237-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06931, KAKENHI-PROJECT-19K07373, KAKENHI-PLANNED-16H06574, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-19H03407, KAKENHI-PROJECT-18K19429, KAKENHI-PROJECT-16H06294
  • [Journal Article] 【食の機能実効分子のサイエンス 食品が生体に与える影響の理解と制御】アミノ酸シグナルの解明からがん治療へ アミノ酸トランスポーター阻害によるがん代謝制御2019

    • Author(s)
      大垣 隆一, 金井 好克
    • Journal Title

      実験医学

      Volume: 37 Pages: 508-513

    • Data Source
      KAKENHI-PROJECT-19H03407
  • [Journal Article] 【食の機能実効分子のサイエンス 食品が生体に与える影響の理解と制御】アミノ酸シグナルの解明からがん治療へ アミノ酸トランスポーター阻害によるがん代謝制御2019

    • Author(s)
      大垣 隆一, 金井 好克
    • Journal Title

      実験医学

      Volume: 37 Pages: 508-513

    • Data Source
      KAKENHI-PROJECT-18K19429
  • [Journal Article] 【最先端プローブによる細胞外微小環境のシグナル計測】PEG結合リン脂質の細胞外表層pHイメージングへの応用 細胞膜アンカー型プローブ骨格としての可能性2019

    • Author(s)
      大垣 隆一, 寺村 裕治, 林 大智, 永森 收志, 高井 まどか, 金井 好克
    • Journal Title

      日本薬理学雑誌

      Volume: 153 Pages: 254-260

    • Data Source
      KAKENHI-PROJECT-19H03407
  • [Journal Article] Structure-activity relationship of a novel series of inhibitors for cancer type transporter L-type amino acid transporter 1 (LAT1).2017

    • Author(s)
      Kongpracha P, Nagamori S, Wiriyasermkul P, Tanaka Y, Kaneda K, Okuda S, Ohgaki R, Kanai Y.
    • Journal Title

      J Pharmacol Sci.

      Volume: 133 Issue: 2 Pages: 96-102

    • DOI

      10.1016/j.jphs.2017.01.006

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04685, KAKENHI-PROJECT-15K15053, KAKENHI-PROJECT-15K21133, KAKENHI-PROJECT-15K08273, KAKENHI-PROJECT-15K08274, KAKENHI-PROJECT-16K19018
  • [Journal Article] Essential roles of L-type amino acid transporter 1 in syncytiotrophoblast development by presenting fusogenic 4F2hc.2017

    • Author(s)
      Ohgaki R, Ohmori T, Hara S, Nakagomi S, Kanai-Azuma M, Kaneda-Nakashima K, Okuda S, Nagamori S, Kanai Y.
    • Journal Title

      Mol Cell Biol.

      Volume: 印刷中 Issue: 11

    • DOI

      10.1128/mcb.00427-16

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04282, KAKENHI-PROJECT-15H04685, KAKENHI-PROJECT-15K15053, KAKENHI-PROJECT-15K08274, KAKENHI-PROJECT-16K19018, KAKENHI-PROJECT-16K15214, KAKENHI-PROJECT-15K08273
  • [Journal Article] Ratiometric fluorescence imaging of cell surface pH by poly(ethylene glycol)-phospholipid conjugated with fluorescein isothiocyanate2017

    • Author(s)
      Ryuichi Ohgaki, Yuji Teramura, Daichi Hayashi, Suguru Okuda, Shushi Nagamori, Madoka Taka and Yoshikatsu Kanai
    • Journal Title

      Sci Res

      Volume: 7 Issue: 1 Pages: 17484-17484

    • DOI

      10.1038/s41598-017-17459-y

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K20085, KAKENHI-PROJECT-16K19018, KAKENHI-PROJECT-15KK0230, KAKENHI-PROJECT-15H04685, KAKENHI-PROJECT-17H04190, KAKENHI-PROJECT-15K08273, KAKENHI-PROJECT-15K08274, KAKENHI-PROJECT-26702017
  • [Journal Article] Novel cystine transporter in renal proximal tubule identified as a missing partner of cystinuria-related plasma membrane protein rBAT/SLC3A1.2016

    • Author(s)
      Nagamori S, Wiriyasermkul P, Guarch ME, Okuyama H, Nakagomi S, Tadagaki K, Nishinaka Y, Bodoy S, Takafuji K, Okuda S, Kurokawa J, Ohgaki R, Nunes V, Palacín M, Kanai Y.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 113 Issue: 3 Pages: 775-780

    • DOI

      10.1073/pnas.1519959113

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08273, KAKENHI-PROJECT-15K08274, KAKENHI-PROJECT-15K15053, KAKENHI-PROJECT-15H04684, KAKENHI-PROJECT-15H04685, KAKENHI-PROJECT-26860171
  • [Journal Article] Specific transport of 3-fluoro-l-α-methyl-tyrosine by LAT1 explains its specificity to malignant tumors in imaging.2016

    • Author(s)
      Wei L, Tominaga H, Ohgaki R, Wiriyasermkul P, Hagiwara K, Okuda S, Kaira K, Oriuchi N, Nagamori S, Kanai Y.
    • Journal Title

      Cancer Sci.

      Volume: 107 Issue: 3 Pages: 347-352

    • DOI

      10.1111/cas.12878

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08273, KAKENHI-PROJECT-15K08274, KAKENHI-PROJECT-26461895, KAKENHI-PROJECT-15K15053, KAKENHI-PROJECT-15H04685, KAKENHI-PROJECT-25461801, KAKENHI-PROJECT-26860171, KAKENHI-PROJECT-16H05393
  • [Journal Article] Interaction of the Sodium/Glucose Cotransporter (SGLT) 2 inhibitor Canagliflozin with SGLT1 and SGLT2: Inhibition kinetics, sidedness of action, and transporter-associated incorporation accounting for its pharmacodynamic and pharmacokinetic features.2016

    • Author(s)
      Ohgaki R, Wei L, Yamada K, Hara T, Kuriyama C, Okuda S, Ueta K, Shiotani M, Nagamori S, Kanai Y.
    • Journal Title

      J Pharmacol Exp Ther.

      Volume: 358 Issue: 1 Pages: 94-102

    • DOI

      10.1124/jpet.116.232025

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04685, KAKENHI-PROJECT-16H06942, KAKENHI-PROJECT-15K15053, KAKENHI-PROJECT-15K08273, KAKENHI-PROJECT-15K08274
  • [Journal Article] Structure-activity relations of leucine derivatives reveal critical moieties for cellular uptake and activation of mTORC1-mediated signaling.2016

    • Author(s)
      Nagamori S, Wiriyasermkul P, Okuda S, Kojima N, Hari Y, Kiyonaka S, Mori Y, Tominaga H, Ohgaki R, Kanai Y.
    • Journal Title

      Amino Acids.

      Volume: 48 Issue: 4 Pages: 279-286

    • DOI

      10.1007/s00726-015-2158-z

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K08273, KAKENHI-PROJECT-15K08274, KAKENHI-PROJECT-25460159, KAKENHI-PROJECT-26461895, KAKENHI-PROJECT-26860171, KAKENHI-PROJECT-15H04685, KAKENHI-PROJECT-15K15053
  • [Journal Article] Impaired Amino Acid Transport at the Blood Brain Barrier Is a Cause of Autism Spectrum Disorder.2016

    • Author(s)
      Tarlungeanu DC, Deliu E, Dotter CP, Kara M, Janiesch PC, Scalise M, Galluccio M, Tesulov M, Morelli E, Sonmez FM, Bilguvar K, Ohgaki R, Kanai Y, Johansen A, Esharif S, Ben-Omran T, Topcu M, Schlessinger A, Indiveri C, Duncan KE, Caglayan AO, Gunel M, Gleeson JG, Novarino G.
    • Journal Title

      Cell.

      Volume: 167 Issue: 6 Pages: 1481-1494

    • DOI

      10.1016/j.cell.2016.11.013

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04685, KAKENHI-PROJECT-15K15053, KAKENHI-PROJECT-15K08273
  • [Journal Article] Transport of 3-fluoro-l-α-methyl-tyrosine (FAMT) by organic ion transporters explains renal background in [(18)F]FAMT positron emission tomography.2016

    • Author(s)
      Wei L, Tominaga H, Ohgaki R, Wiriyasermkul P, Hagiwara K, Okuda S, Kaira K, Kato Y, Oriuchi N, Nagamori S, Kanai Y.
    • Journal Title

      J Pharmacol Sci.

      Volume: 130 Issue: 2 Pages: 101-109

    • DOI

      10.1016/j.jphs.2016.01.001

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08273, KAKENHI-PROJECT-15K08274, KAKENHI-PROJECT-26461895, KAKENHI-PROJECT-15K15053, KAKENHI-PROJECT-15H04685, KAKENHI-PROJECT-25461801, KAKENHI-PROJECT-26860171, KAKENHI-PROJECT-16H05393
  • [Journal Article] Boronophenylalanine, a boron delivery agent for boron neutron capture therapy, is transported by ATB(0,+) , LAT1 and LAT2.2015

    • Author(s)
      Wongthai P, Hagiwara K, Miyoshi Y, Wiriyasermkul P, Wei L, Ohgaki R, Kato I, Hamase K, Nagamori S, Kanai Y.
    • Journal Title

      Cancer Sci.

      Volume: 106 Issue: 3 Pages: 279-86

    • DOI

      10.1111/cas.12602

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390217, KAKENHI-PROJECT-24591198, KAKENHI-PUBLICLY-25136714, KAKENHI-PROJECT-26670123
  • [Journal Article] Nicotine induces dendritic spine remodeling in cultured hippocampal neurons.2014

    • Author(s)
      Oda A^1, Yamagata K, Nakagomi S, Uejima H, Wiriyasermkul P, Ohgaki R, Nagamori S, Kanai Y, Tanaka H.
    • Journal Title

      J Neurochem.

      Volume: 128(2) Issue: 2 Pages: 246-255

    • DOI

      10.1111/jnc.12470

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J40095, KAKENHI-PROJECT-23590300, KAKENHI-PROJECT-24390217, KAKENHI-PROJECT-24591198, KAKENHI-PROJECT-24659093, KAKENHI-PUBLICLY-25110737, KAKENHI-PUBLICLY-25136714, KAKENHI-PROJECT-25293239, KAKENHI-PROJECT-25870403
  • [Journal Article] Linkage of N-cadherin to multiple cytoskeletal elements revealed by a proteomic approach in hippocampal neurons.2012

    • Author(s)
      Tanaka H, Takafuji K, Taguchi A, Wiriyasermkul P, Ohgaki R, Nagamori S, Suh PG, Kanai Y.
    • Journal Title

      Neurochem Int.

      Volume: 61 Issue: 2 Pages: 240-250

    • DOI

      10.1016/j.neuint.2012.05.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590300, KAKENHI-PROJECT-23790334, KAKENHI-PROJECT-24390217, KAKENHI-PROJECT-24591198, KAKENHI-PROJECT-24659116, KAKENHI-PUBLICLY-23136509
  • [Journal Article] Establishment of stable cell lines with high expression of heterodimers of human 4F2hc and human amino acid transporter LAT1 or LAT2 and delineation of their differential interaction with α-alkyl moieties.2012

    • Author(s)
      Khunweeraphong N, Nagamori S, Wiriyasermkul P, Nishinaka Y, Wongthai P, Ohgaki R, Tanaka H, Tominaga H, Sakurai H, Kanai Y.
    • Journal Title

      Journal of Pharmacological Science

      Volume: 119 Pages: 368-380

    • NAID

      10031071638

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790334
  • [Journal Article] Transport of 3-fluoro-L-alpha-methyl tyrosine by tumor-upregulated amino acid transporter LAT1: a cause of the tumor uptake in PET.2012

    • Author(s)
      Wiriyasermkul P, Nagamori S, Tominaga H, Oriuchi N, Kaira K, Nakao H, Kitashoji T, Ohgaki R, Tanaka H, Endou H, Endo K, Sakurai H, Kanai Y.
    • Journal Title

      Journal of Nuclear Medicine

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790334
  • [Journal Article] Establishment of Stable Cell Lines With High Expression of Heterodimers of Human 4F2hc and Human Amino Acid Transporter LAT1 or LAT2 and Delineation of Their Differential Interaction With <I>&alpha;</I>-Alkyl Moieties2012

    • Author(s)
      Narakorn Khunweeraphong
    • Journal Title

      J Pharmacol Sci

      Volume: 119 Issue: 4 Pages: 368-380

    • DOI

      10.1254/jphs.12124FP

    • NAID

      10031071638

    • ISSN
      1347-8613, 1347-8648
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10J40082, KAKENHI-PROJECT-24591198, KAKENHI-PROJECT-24659116, KAKENHI-PUBLICLY-23136509
  • [Journal Article] Linkage of N-cadherin to Multiple Cytoskeletal Elements Revealed by a Proteomic Approach in Hippocampal Neurons2012

    • Author(s)
      Tanaka H., Takafuji K., Taguchi A., Wiriyasermkul P., Ohgaki R., Nagamori S., Suh P-G., Kanai Y.
    • Journal Title

      Neurochem Int

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659052
  • [Journal Article] Linkage of N-cadherin to multiple cytoskeletal elements revealed by a proteomic approach in hippocampal neurons2012

    • Author(s)
      Tanaka H, Takafuji K, Taguchi A, Wiriyasermkul P, Ohgaki R, Nagamori S, Suh PG, Kanai Y.
    • Journal Title

      Neurochem Int

      Volume: 61 Pages: 240-250

    • Data Source
      KAKENHI-PROJECT-23790334
  • [Journal Article] NRFL-1, the C. elegans NHERF Orthologue, Interacts with Amino Acid Transporter 6 (AAT-6) for Age-Dependent Maintenance of AAT-6 on the Membrane.2012

    • Author(s)
      Kohei Hagiwara
    • Journal Title

      Plos one

      Volume: 7(8) Issue: 8 Pages: e43050-e43050

    • DOI

      10.1371/journal.pone.0043050

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J40095, KAKENHI-PROJECT-23590300, KAKENHI-PROJECT-23790256, KAKENHI-PROJECT-23790334, KAKENHI-PROJECT-24390053, KAKENHI-PROJECT-24390217, KAKENHI-PROJECT-24591198, KAKENHI-PROJECT-24659116, KAKENHI-PUBLICLY-23136509
  • [Journal Article] Transport of 3-fluoro-L-α-methyl tyrosine by tumor-pregulated amino acid transporter LAT1 : a cause of the tumor uptake in PET2012

    • Author(s)
      Wiriyasermkul, P. Nagamori S, Tominaga H, Oriuchi N, Kaira K, Nakao H, Kitashoji T, Ohgaki R. Tanaka H, Endou H, Endo K, Sakurai H and Kanai Y
    • Journal Title

      J Nucl Med

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659052
  • [Journal Article] Linkage of N-cadherin to Multiple Cytoskeletal Elements Revealed by a Proteomic Approach in Hippocampal Neurons2012

    • Author(s)
      Tanaka H., Takafuji K., Taguchi A., Wiriyasermkul P., Ohgaki R., Nagamori S., Suh P-G., Kanai Y
    • Journal Title

      Neurochem Int

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390264
  • [Journal Article] Transport of 3-fluoro-L-alpha-methyl-tyrosine by tumor-upregulated L-type amino acid transporter 1: a cause of the tumor uptake in PET2012

    • Author(s)
      Wiriyasermkul P, Nagamori S, Tominaga H, Oriuchi N, Kaira K, Nakao H, Kitashoji T, Ohgaki R, Tanaka H, Endou H, Endo K, Sakurai H, Kanai Y
    • Journal Title

      J Nucl Med

      Volume: 53 Pages: 1253-1261

    • Data Source
      KAKENHI-PROJECT-23790334
  • [Journal Article] Transport of 3-fluoro-L-α-methyl-tyrosine by tumor-upregulated L-type amino acid transporter 1: a cause of the tumor uptake in PET.2012

    • Author(s)
      Wiriyasermkul P, Nagamori S, Tominaga H, Oriuchi N, Kaira K, Nakao H, Kitashoji T, Ohgaki R, Tanaka H, Endou H, Endo K, Sakurai H, Kanai Y.
    • Journal Title

      J Nucl Med.

      Volume: 53 Issue: 8 Pages: 1253-1261

    • DOI

      10.2967/jnumed.112.103069

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590300, KAKENHI-PROJECT-23790334, KAKENHI-PROJECT-24390217, KAKENHI-PROJECT-24591198, KAKENHI-PROJECT-24659116, KAKENHI-PROJECT-24659573
  • [Journal Article] NRFL-1, the C. elegans NHERF orthologue, interacts with amino acid transporter 6 (AAT-6) for age-dependent maintenance of AAT-6 on the membrane2012

    • Author(s)
      Hagiwara K, Nagamori S, Umemura YM, Ohgaki R, Tanaka H, Murata D, Nakagomi S, Nomura KH, Kage-Nakadai E, Mitani S, Nomura K, Kanai Y
    • Journal Title

      PLoS One

      Volume: 7

    • Data Source
      KAKENHI-PROJECT-23790334
  • [Journal Article] Establishment of stable cell lines with high expression of heterodimers of human 4F2hc and human amino acid transporter LAT1 or LAT2 and delineation of their differential interaction with a-alkyl moieties.2012

    • Author(s)
      Khunweeraphong N, Nagamori S, Wiriyasermkul P, Nishinaka Y, Wongthai P, Ohgaki R, Tanaka H, Tominaga H, Sakurai H, Kanai Y.
    • Journal Title

      J Pharmacol Sci

      Volume: 119 Pages: 368-380

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390217
  • [Journal Article] Establishment of stable cell lines with high expression of heterodimers of human 4F2hc and human amino acid transporter LAT1 or LAT2 and delineation of their differential interaction with α-alkyl moieties2012

    • Author(s)
      Khunweeraphong N, Nagamori S, Wiriyasermkul P, Nishinaka Y, Wongthai P, Ohgaki R, Tanaka H,Tominaga H, Sakurai H, Kanai Y
    • Journal Title

      J Pharmacol Sci

      Volume: 119 Pages: 368-380

    • NAID

      10031071638

    • Data Source
      KAKENHI-PROJECT-23790334
  • [Journal Article] Transport of 3-fluoro-L-α-methyl tyrosine by tumor-pregulated amino acid transporter LAT1 : a cause of the tumor uptake in PET2012

    • Author(s)
      Wiriyasermkul, P. Nagamori S, Tominaga H, Oriuchi N, Kaira K, Nakao H, Kitashoji T, Ohgaki R. Tanaka H, Endou H, Endo K, Sakurai H and Kanai Y
    • Journal Title

      J Nucl Med

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390264
  • [Journal Article] Differential effects of TNF (TNFSF2) and IFN-γ on intestinal epithelial cell morphogenesis and barrier function in three-dimensional culture2011

    • Author(s)
      Juuti-Uusitalo K, Klunder LJ, Sjollema KA, Mackovicova K, Ohgaki R, Hoekstra D, Dekker J, van Ijzendoorn SC
    • Journal Title

      PLoS One

      Volume: 6

    • Data Source
      KAKENHI-PROJECT-23790334
  • [Journal Article] Organellar Na+/H+ exchangers: novel players in organelle pH regulation and their emerging functions.2011

    • Author(s)
      Ohgaki R, van IJzendoorn SC, Matsushita M, Hoekstra D, Kanazawa H
    • Journal Title

      Biochemistry

      Volume: 50 Pages: 443-450

    • Data Source
      KAKENHI-PROJECT-23790334
  • [Journal Article] Dick Hoekstra, and Hiroshi KanazawaOrganellar Na+/H+ exchangers: Novel players in organelle pH regulation and their emerging functions2011

    • Author(s)
      Ryuichi Ohgaki, Sven C.D.van Ijzendoorn, Masafumi Matsushita
    • Journal Title

      Biochemistry

      Volume: 50 Pages: 443-450

    • Data Source
      KAKENHI-PROJECT-21370055
  • [Journal Article] Differential effects of TNF (TNFSF2) and IFN-γ on intestinal epithelial cell morphogenesis and barrier function in three-dimensional culture.2011

    • Author(s)
      Juuti-Uusitalo K, Klunder LJ, Sjollema KA, Mackovicova K, Ohgaki R, Hoekstra D, Dekker J, van Ijzendoorn SC.
    • Journal Title

      PLoS One

      Volume: 6 Issue: 8 Pages: e22967-e22967

    • DOI

      10.1371/journal.pone.0022967

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790334
  • [Journal Article] Dick Hoekstra1, and Sven C.D. van IJzendoorn1*The Na+/H+ exchanger NHE6 in the endosomal recycling system is involved in the development of apical bile canalicular surface domains in HepG2 cells2010

    • Author(s)
      Ryuichi Ohgaki, Masafumi Matsushita, Hiroshi Kanazawa, Satoshi Ogihara2
    • Journal Title

      Mol. Biol. Cell.

      Volume: 21 Pages: 1293-1304

    • Data Source
      KAKENHI-PROJECT-21370055
  • [Journal Article] A membrane-proximal region in the C-terminal tail of NHE7 is required for its distribution in the trans-Golgi network, distinct from NHE6 localization at endosomes2010

    • Author(s)
      Naomi Fukura・Ryuichi Ohgaki・Masafumi Matsushita・Norihiro Nakamura, Keiji Mitsui, Hiroshi Kanazawa
    • Journal Title

      J.Membrane Biol.

      Volume: 234 Pages: 149-158

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21370055
  • [Journal Article] Membrane proximal region in the C-terminal tail of NHE7 is required for its distribution in the trans-Golgi network, distinct from NHE6 localization at endosomes2010

    • Author(s)
      Naomi Fukura, Ryuichi Ohgaki, Masafumi Matsushita, Norihiro Nakamura, Keiji Mitsui, and Hiroshi Kanazawa
    • Journal Title

      J Membrane Biol.

      Volume: 234 Pages: 149-158

    • Data Source
      KAKENHI-PROJECT-21370055
  • [Journal Article] The Na^+/H^+ Exchanger NHE6 in the Endosomal Recycling System Is Involved in the Development of Apical Bile Canalicular Surface Domains in HepG2 Cells2010

    • Author(s)
      Ryuichi Ohgaki, Masafumi Matsushita, Hiroshi Kanazawa, Satoshi Ogihara, Dick Hoekstra, Sven C.D.van IJzendoorn
    • Journal Title

      Mol.Biol.Cell.

      Volume: 21 Pages: 1293-1304

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21370055
  • [Journal Article] 高等動物オルガネラ局在性Na+/H+交換輸送体の局在・活性・生理機能2010

    • Author(s)
      大垣隆一、松下昌史、金澤浩
    • Journal Title

      生化学

      Volume: 82 Pages: 577-590

    • NAID

      10026607490

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21370055
  • [Patent] がん治療剤2020

    • Inventor(s)
      金井 好克、大垣 隆一、遠藤 仁、鈴木 登紀子
    • Industrial Property Rights Holder
      ジェイファーマ株式、国立大学法人大阪大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-187983
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-18K06931
  • [Patent] がん治療剤2020

    • Inventor(s)
      金井 好克、大垣 隆一、遠藤 仁、鈴木 登紀子
    • Industrial Property Rights Holder
      ジェイファーマ株式、国立大学法人大阪大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-187983
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-19H03407
  • [Presentation] がん細胞におけるアミノ酸トランスポーター LAT1 の阻害は p38 MAPK 活性化を介したサイクリン D1 の下方制御により G0/G1 期から S 期への移行を抑制する2024

    • Author(s)
      Zhou Xinyu、大垣 隆一、Jin Chunhuan、Xu Minhui、岡西 広樹、遠藤 仁、金井 好克
    • Organizer
      第144回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-23K24071
  • [Presentation] がん細胞におけるアミノ酸トランスポーターLAT1の阻害はp38 MAPK活性化を介したサイクリンD1の下方制御によりG0/G1期からS期への移行を抑制する2024

    • Author(s)
      Zhou Xinyu、大垣 隆一、Jin Chunhuan、Xu Minhui、岡西 広樹、遠藤 仁、金井 好克
    • Organizer
      第144回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-22K06856
  • [Presentation] がん細胞におけるアミノ酸トランスポーター LAT1 の阻害は p38 MAPK 活性化を介したサイクリン D1 の下方制御により G0/G1 期から S 期への移行を抑制する2024

    • Author(s)
      Zhou Xinyu、大垣 隆一、Jin Chunhuan、Xu Minhui、岡西 広樹、遠藤 仁、金井 好克
    • Organizer
      第144回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-22K19404
  • [Presentation] 膵臓がん及び胆管がん細胞に対するアミノ酸トランスポーターLAT1阻害薬nanvuranlatと細胞障害性抗がん薬の併用効果の検討2023

    • Author(s)
      西窪 航、大垣 隆一、劉 星明、岡西 広樹、徐 旻恵;、遠藤 仁、金井 好克
    • Organizer
      第143回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-23K24071
  • [Presentation] 個々のアミノ酸の細胞内濃度の経時変化と機能に着目したLAT1阻害薬のがん細胞増殖抑制のメカニズムの解明2023

    • Author(s)
      西窪 航、大垣 隆一、岡西 広樹、徐 旻恵;、遠藤 仁、金井 好克
    • Organizer
      第97回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-23K24071
  • [Presentation] 個々のアミノ酸の細胞内濃度の経時変化と機能に着目したLAT1阻害薬のがん細胞増殖抑制のメカニズムの解明2023

    • Author(s)
      西窪 航、大垣 隆一、岡西 広樹、徐 旻恵、遠藤 仁、金井 好克
    • Organizer
      第97回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-22K19404
  • [Presentation] 低酸素誘導因子の蓄積が大腸がん細胞におけるアミノ酸トランスポーターLAT1の発現に与える影響2023

    • Author(s)
      大垣 隆一、平瀬 悠真、岡西 広樹、徐 旻恵;、金井 好克
    • Organizer
      第97回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-23K24071
  • [Presentation] 個々のアミノ酸の細胞内濃度の経時変化と機能に着目したLAT1阻害薬のがん細胞増殖抑制のメカニズムの解明2023

    • Author(s)
      西窪 航、大垣 隆一、岡西 広樹、徐 旻ケイ、遠藤 仁、金井 好克
    • Organizer
      第97回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-22K06856
  • [Presentation] 膵臓がん及び胆管がん細胞に対するアミノ酸トランスポーターLAT1阻害薬nanvuranlatと細胞障害性抗がん薬の併用効果の検討2023

    • Author(s)
      西窪 航、大垣 隆一、劉 星明、岡西 広樹、徐 旻ケイ、遠藤 仁、金井 好克.膵臓がん及び胆管がん細胞に対するアミノ酸トランスポーターLAT1阻害薬nanvuranlatと細胞障害性抗がん薬の併用効果の検討
    • Organizer
      第143回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-22K06856
  • [Presentation] 低酸素誘導因子の蓄積が大腸がん細胞におけるアミノ酸トランスポーターLAT1の発現に与える影響2023

    • Author(s)
      大垣 隆一、平瀬 悠真、岡西 広樹、徐 旻ケイ、金井 好克
    • Organizer
      第97回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-22K06856
  • [Presentation] 膵臓がん及び胆管がん細胞に対するアミノ酸トランスポーターLAT1阻害薬nanvuranlatと細胞障害性抗がん薬の併用効果の検討2023

    • Author(s)
      西窪 航、大垣 隆一、劉 星明、岡西 広樹、徐 旻恵、遠藤 仁、金井 好克
    • Organizer
      第143回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-22K19404
  • [Presentation] 低酸素誘導因子の蓄積が大腸がん細胞におけるアミノ酸トランスポーターLAT1の発現に与える影響2023

    • Author(s)
      大垣 隆一、平瀬 悠真、岡西 広樹、徐 旻恵、金井 好克
    • Organizer
      第97回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-22K19404
  • [Presentation] 内在性モノカルボン酸トランスポーター MCT1 との機能共役はHEK293 細胞において発現させた有機アニオントランスポーター OAT10 の輸送機能に影響する2023

    • Author(s)
      大津 尚子、大垣 隆一、金 春奐、徐 旻恵、岡西 広樹、髙橋 亮、松井 明子、佐藤 正延、岸本 航、石黒 直樹、金井 好克
    • Organizer
      第97回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-23K24071
  • [Presentation] 内在性モノカルボン酸トランスポーター MCT1 との機能共役はHEK293 細胞において発現させた有機アニオントランスポーター OAT10 の輸送機能に影響する2023

    • Author(s)
      大津 尚子、大垣 隆一、金 春奐、徐 旻恵、岡西 広樹、髙橋 亮、松井 明子、佐藤 正延、岸本 航、石黒 直樹、金井 好克
    • Organizer
      第97回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-22K19404
  • [Presentation] アミノ酸トランスポーターLAT1阻害薬のT細胞活性化によるPD-1阻害薬抗腫瘍効果の増進2023

    • Author(s)
      徐 旻恵, 周 新宇, 金 春奐, 岡西 広樹, 大垣 隆一, 遠藤 仁, 金井 好克
    • Organizer
      第82回 日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K24071
  • [Presentation] アミノ酸トランスポーターLAT1阻害薬のT細胞活性化によるPD-1阻害薬抗腫瘍効果の増進2023

    • Author(s)
      徐 旻恵, 周 新宇, 金 春奐, 岡西 広樹, 大垣 隆一, 遠藤 仁, 金井 好克
    • Organizer
      第82回 日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K19404
  • [Presentation] 内在性モノカルボン酸トランスポーターMCT1との機能共役はHEK293細胞において発現させた有機アニオントランスポーターOAT10の輸送機能に影響する2023

    • Author(s)
      大津 尚子、大垣 隆一、金 春奐、徐 旻ケイ、岡西 広樹、髙橋 亮、松井 明子、佐藤 正延、岸本 航、石黒 直樹、金井 好克
    • Organizer
      第97回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-22K06856
  • [Presentation] アミノ酸トランスポーターLAT1の阻害はがん細胞における大型中性アミノ酸輸送を顕著に低下させグローバルな翻訳抑制を誘導する2022

    • Author(s)
      西窪 航, 大垣 隆一, 岡西 広樹, 奥田 傑, Xu Minhui, 遠藤 仁, 金井 好克
    • Organizer
      第96回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-22K06856
  • [Presentation] アミノ酸トランスポーターLAT1の阻害はがん細胞における大型中性アミノ酸輸送を顕著に低下させグローバルな翻訳抑制を誘導する2022

    • Author(s)
      西窪 航, 大垣 隆一, 岡西 広樹, 奥田 傑, Xu Minhui, 遠藤 仁, 金井 好克
    • Organizer
      第96回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-23K24071
  • [Presentation] アミノ酸トランスポーターLAT1阻害薬が腫瘍細胞の大型中性アミノ酸輸送とタンパク質合成に与える影響2022

    • Author(s)
      西窪 航, 大垣 隆一, 岡西 広樹, 奥田 傑, Xu Minhui, 遠藤 仁, 金井 好克
    • Organizer
      第141回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-23K24071
  • [Presentation] Evaluation of LAT1 expression in patients with lung cancers and mediastinal tumors: [18F]FBPA PET study with immuno-histopathological comparison2022

    • Author(s)
      T. Watabe, N. Ose, S. Naka, E. Fukui, T. Kanou, S. Funaki, H. Sasaki, T. Kamiya, K. Kurimoto, E. Shimosegawa, H. Kato, R. Ohgaki, Y. Kanai, Y. Shintani
    • Organizer
      EANM'22 - Annual Congress of the European Association of Nuclear Medicine
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06856
  • [Presentation] がん細胞由来エクソソーム上におけるアミノ酸トランスポーターLAT1(SLC7A5)の発現:予後および診断バイオマーカーとしての潜在的価 値2022

    • Author(s)
      大垣 隆一, Liu Yumiao, Xu Minhui, 岡西 広樹, 金井 好克
    • Organizer
      第96回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-22K19404
  • [Presentation] 腸管腫瘍におけるアミノ酸トランスポーターLAT1の役割について2022

    • Author(s)
      隋 雲竜, 星 奈美子, 大垣 隆一, 伊藤 裕貴, 小谷 武徳, 的崎 尚, 児玉 裕三
    • Organizer
      第81回 日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K06856
  • [Presentation] アミノ酸トランスポーターLAT1阻害薬が腫瘍細胞の大型中性アミノ酸輸送とタンパク質合成に与える影響2022

    • Author(s)
      西窪 航, 大垣 隆一, 岡西 広樹, 奥田 傑, Xu Minhui, 遠藤 仁, 金井 好克
    • Organizer
      第141回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-22K19404
  • [Presentation] がん特異的アミノ酸トランスポーターLAT1阻害薬JPH203による胆道がん細胞内アミノ酸プールの破綻に伴うリン酸化プロテオーム解析2022

    • Author(s)
      岡西 広樹, 大垣 隆一, Xu Minhui, 遠藤 仁, 金井 好克
    • Organizer
      第142回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-22K19404
  • [Presentation] がん細胞由来エクソソーム上におけるアミノ酸トランスポーターLAT1(SLC7A5)の発現:予後および診断バイオマーカーとしての潜在的価 値2022

    • Author(s)
      大垣 隆一, Liu Yumiao, Xu Minhui, 岡西 広樹, 金井 好克
    • Organizer
      第96回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-23K24071
  • [Presentation] Evaluation of LAT1 expression in patients with lung cancers and mediastinal tumors: [18F]FBPA PET study with immunohistopathological comparison2022

    • Author(s)
      T. Watabe, N. Ose, S. Naka, E. Fukui, T. Kanou, S. Funaki, H. Sasaki, T. Kamiya, K. Kurimoto, E. Shimosegawa, H. Kato, R. Ohgaki, Y. Kanai, Y. Shintani
    • Organizer
      EANM'22 - Annual Congress of the European Association of Nuclear Medicine
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24071
  • [Presentation] がん特異的アミノ酸トランスポーターLAT1 阻害薬JPH203 による胆道がん細胞内 アミノ酸プールの破綻に伴うリン酸化プロテオーム解析2022

    • Author(s)
      岡西 広樹, 大垣 隆一, Xu Minhui, 遠藤 仁, 金井 好克
    • Organizer
      第142回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-23K24071
  • [Presentation] アミノ酸トランスポーターLAT1の阻害はがん細胞における大型中性アミノ酸輸送を顕著に低下させグローバルな翻訳抑制を誘導する2022

    • Author(s)
      西窪 航, 大垣 隆一, 岡西 広樹, 奥田 傑, Xu Minhui, 遠藤 仁, 金井 好克
    • Organizer
      第96回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-22K19404
  • [Presentation] がん特異的アミノ酸トランスポーターLAT1 阻害薬JPH203 による胆道がん細胞内 アミノ酸プールの破綻に伴うリン酸化プロテオーム解析2022

    • Author(s)
      岡西 広樹, 大垣 隆一, Xu Minhui, 遠藤 仁, 金井 好克
    • Organizer
      第142回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-22K06856
  • [Presentation] Evaluation of LAT1 expression in patients with lung cancers and mediastinal tumors: [18F]FBPA PET study with immunohistopathological comparison2022

    • Author(s)
      T. Watabe, N. Ose, S. Naka, E. Fukui, T. Kanou, S. Funaki, H. Sasaki, T. Kamiya, K. Kurimoto, E. Shimosegawa, H. Kato, R. Ohgaki, Y. Kanai, Y. Shintani
    • Organizer
      EANM'22 - Annual Congress of the European Association of Nuclear Medicine
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K19404
  • [Presentation] アミノ酸トランスポーターLAT1阻害薬が腫瘍細胞の大型中性アミノ酸輸送とタンパク質合成に与える影響2022

    • Author(s)
      西窪 航, 大垣 隆一, 岡西 広樹, 奥田 傑, Xu Minhui, 遠藤 仁, 金井 好克
    • Organizer
      第141回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-22K06856
  • [Presentation] がん細胞由来エクソソーム上におけるアミノ酸トランスポーターLAT1(SLC7A5)の発現:予後および診断バイオマーカーとしての潜在的価値2022

    • Author(s)
      大垣 隆一, Liu Yumiao, Xu Minhui, 岡西 広樹, 金井 好克
    • Organizer
      第96回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-22K06856
  • [Presentation] Amino acid transporter LAT1 is upregulated in tumor-associated vascular endothelial cells and plays essential roles in tumor angiogenesis by promoting proliferation and regulating VEGF-A-dependent pro-angiogenic mTORC1 activation2021

    • Author(s)
      Ryuichi Ohgaki、Lili Quan、Suguru Okuda、Hiroki Okanishi、Shushi Nagamori、Hitoshi Endou、Yoshikatsu Kanai
    • Organizer
      第94回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-19H03407
  • [Presentation] アミノ酸トランスポーターLAT1阻害薬JPH203による胆道がん細胞増殖抑制機構に関わるプロテオミクスおよびリン酸化プロテオミクス解析2021

    • Author(s)
      岡西 広樹、大垣 隆一、奥田 傑、遠藤 仁、金井 好克
    • Organizer
      第94回 日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-19H03407
  • [Presentation] Suppression of proliferation of cholangiocarcinoma cells by miRNAs targeting L type amino acid transporter 1 downregulated in cholangiocarcinomas2021

    • Author(s)
      劉 星明、大垣 隆一、岡西 広樹、奥田 傑、徐 旻ケイ、金井 好克
    • Organizer
      第139回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-19H03407
  • [Presentation] アミノ酸トランスポーターを標的としたがん治療の可能性:抗腫瘍効果の基盤となる多様な機序の存在2021

    • Author(s)
      大垣隆一
    • Organizer
      第20回 横断的腫瘍フォーラム(大阪大学)
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03407
  • [Presentation] 腫瘍血管新生におけるアミノ酸トランスポーターLAT1 の機能2021

    • Author(s)
      大垣 隆一
    • Organizer
      第1 回 トランスポーター研究会関西部会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03407
  • [Presentation] Amino acid transporter LAT1 is upregulated in tumor-associated vascular endothelial cells and plays essential roles in tumor angiogenesis by promoting proliferation and regulating VEGF-A-dependent pro-angiogenic mTORC1 activation2021

    • Author(s)
      Ryuichi Ohgaki、Lili Quan、Suguru Okuda、Hiroki Okanishi、Shushi Nagamori、Hitoshi Endou、Yoshikatsu Kanai
    • Organizer
      第94回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-18K06931
  • [Presentation] がん細胞におけるLAT1のアミノ酸の取込みへの寄与とLAT1阻害薬によるタンパク質合成抑制効果2021

    • Author(s)
      西窪 航、大垣 隆一、岡西 広樹、奥田 傑、徐 旻ケイ、遠藤 仁、金井 好克
    • Organizer
      第95回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-19H03407
  • [Presentation] 胆道がん細胞株におけるアミノ酸トランスポーターLAT1阻害薬が示す増殖抑制作用のタンパク質発現・リン酸化変動の網羅的解析による検討2021

    • Author(s)
      岡西 広樹、大垣 隆一、奥田 傑、遠藤 仁、金井 好克
    • Organizer
      第140回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-19H03407
  • [Presentation] 血管内皮細胞におけるアミノ酸トランスポーターLAT1の発現亢進とVEGF-Aシグナルの制御による腫瘍血管新生への寄与2021

    • Author(s)
      大垣隆一
    • Organizer
      第3回 生命医科学若手研究者の会(大阪大学)
    • Data Source
      KAKENHI-PROJECT-19H03407
  • [Presentation] 遊離アミノ酸量の定量的経時変化解析によるアミノ酸トランスポーター阻害効果の検討2020

    • Author(s)
      西窪 航、大垣 隆一、岡西 広樹、奥田 傑、金井 好克
    • Organizer
      第137回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-18K06931
  • [Presentation] Suppression of LAT1 in endothelial cells of tumor tissues exhibits an anti-angiogenesis effect2020

    • Author(s)
      Lili Quan, Ryuichi Ohgaki, Suguru Okuda, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第93回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-19H03407
  • [Presentation] Suppression of LAT1 in endothelial cells of tumor tissues exhibits an anti-angiogenesis effect2020

    • Author(s)
      Lili Quan, Ryuichi Ohgaki, Suguru Okuda, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第93回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-18K06931
  • [Presentation] Time-course analysis of the changes in intracellular amino acid concentrations and amino acid-related signaling pathways in cancer cells induced by the inhibition of cancer-type amino acid transporter LAT12020

    • Author(s)
      西窪 航, 大垣 隆一, 岡西 広樹, 奥田 傑, 金井 好克
    • Organizer
      第93回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-19H03407
  • [Presentation] 遊離アミノ酸量の定量的経時変化解析によるアミノ酸トランスポーター阻害効果の検討2020

    • Author(s)
      西窪 航、大垣 隆一、岡西 広樹、奥田 傑、金井 好克
    • Organizer
      第137回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-19H03407
  • [Presentation] Development of tumor-specific compounds avoiding renal uptake for PET imaging and targeted α-therapy2020

    • Author(s)
      Chunhuan Jin、Ling Wei、Ryuichi Ohgaki、Suguru Okuda、Minhui Xu、Hiroki Okanishi、Shushi Nagamori、Yoshikatsu Kanai
    • Organizer
      第138回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-19H03407
  • [Presentation] Critical moieties of aromatic amino acid probes causing renal accumulation in tumor imaging2020

    • Author(s)
      Chunhuan Jin, Ling Wei, Ryuichi Ohgaki, Suguru Okuda, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第93回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-18K19429
  • [Presentation] Development of tumor-specific compounds avoiding renal uptake for PET imaging and targeted α-therapy2020

    • Author(s)
      Chunhuan Jin、Ling Wei、Ryuichi Ohgaki、Suguru Okuda、Minhui Xu、Hiroki Okanishi、Shushi Nagamori、Yoshikatsu Kanai
    • Organizer
      第138回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-18K06931
  • [Presentation] Critical moieties of aromatic amino acid probes causing renal accumulation in tumor imaging2020

    • Author(s)
      Chunhuan Jin, Ling Wei, Ryuichi Ohgaki, Suguru Okuda, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第93回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-19H03407
  • [Presentation] Time-course analysis of the changes in intracellular amino acid concentrations and amino acid-related signaling pathways in cancer cells induced by the inhibition of cancer-type amino acid transporter LAT2020

    • Author(s)
      西窪 航、大垣 隆一、岡西 広樹、奥田 傑、金井 好克
    • Organizer
      第93回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-18K06931
  • [Presentation] Time-course analysis of the changes in intracellular amino acid concentrations and amino acid-related signaling pathways in cancer cells induced by the inhibition of cancer-type amino acid transporter LAT12020

    • Author(s)
      西窪 航, 大垣 隆一, 岡西 広樹, 奥田 傑, 金井 好克
    • Organizer
      第93回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-18K19429
  • [Presentation] Suppression of LAT1 in endothelial cells of tumor tissues exhibits an anti-angiogenesis effect2020

    • Author(s)
      Lili Quan, Ryuichi Ohgaki, Suguru Okuda, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第93回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-18K19429
  • [Presentation] Identification of miRNA regulating the expression of cancer-type amino acid transporter LAT1: its potential as an antionco-miRNA2019

    • Author(s)
      劉 星明、大垣 隆一、岡西 広樹、奥田 傑、金井 好克
    • Organizer
      第136回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-18K06931
  • [Presentation] Expression of amino acid transporter LAT1 in the endothelial cells of tumor tissues and its contribution to angiogenesis2019

    • Author(s)
      Lili Quan, Ryuichi Ohgaki, Suguru Okuda, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第135回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-18K19429
  • [Presentation] Identification of miRNA regulating the expression of cancer-type amino acid transporter LAT1: its potential as an antionco-miRNA2019

    • Author(s)
      劉 星明, 大垣 隆一, 岡西 広樹, 奥田 傑, 金井 好克
    • Organizer
      第136回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-18K19429
  • [Presentation] アミノ酸トランスポーターによる多様な細胞機能制御と創薬標的としての意義2019

    • Author(s)
      大垣隆一
    • Organizer
      第393回 大阪大学臨床栄養研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19429
  • [Presentation] Expression of amino acid transporter LAT1 in the endothelial cells of tumor tissues and its contribution to angiogenesis2019

    • Author(s)
      Lili Quan, Ryuichi Ohgaki, Suguru Okuda, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第135回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-19H03407
  • [Presentation] ヘテロ二量型アミノ酸トランスポーター複合体LAT1-4F2hcは胎盤の合胞体性栄養膜形成に必須の細胞融合因子である2019

    • Author(s)
      大垣 隆一, 大森 崇弘, 原 早織, 中込 咲綾, 金井 正美, 兼田(中島)加珠子, 奥田 傑, 永森 收志, 金井 好克
    • Organizer
      第66回 日本生化学会近畿支部例会
    • Data Source
      KAKENHI-PROJECT-19H03407
  • [Presentation] アミノ酸トランスポーターによる多様な細胞機能制御と創薬標的としての意義2019

    • Author(s)
      大垣隆一
    • Organizer
      第393回 大阪大学臨床栄養研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K06931
  • [Presentation] アミノ酸アベイラビリティが細胞内遊離アミノ酸濃度に与える影響2019

    • Author(s)
      西窪 航、大垣 隆一、岡西 広樹、奥田 傑、金井 好克
    • Organizer
      第92回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-18K19429
  • [Presentation] 腫瘍血管内皮細胞における必須アミノ酸 トランスポーターの発現亢進と血管新生への寄与2019

    • Author(s)
      大垣隆一
    • Organizer
      第2回 がんと代謝研究会若手の会
    • Data Source
      KAKENHI-PROJECT-18K06931
  • [Presentation] Comparative phosphoproteomics between non-competitive and competitive inhibitions of L-type amino acid transporter 1 in cancer cells.2019

    • Author(s)
      Kongpracha Pornparn、Wiriyasermkul Pattama、田中 容子、奥田 傑、大垣 隆一、金井 好克、永森 收志
    • Organizer
      第92回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-18K19429
  • [Presentation] ヘテロ二量型アミノ酸トランスポーター複合体LAT1-4F2hcは胎盤の合胞体性栄養膜形成に必須の細胞融合因子である2019

    • Author(s)
      大垣 隆一, 大森 崇弘, 原 早織, 中込 咲綾, 金井 正美, 兼田(中島)加珠子, 奥田 傑, 永森 收志, 金井 好克
    • Organizer
      第66回 日本生化学会近畿支部例会
    • Data Source
      KAKENHI-PROJECT-18K19429
  • [Presentation] Expression of amino acid transporter LAT1 in the endothelial cells of tumor tissues and its contribution to angiogenesis2019

    • Author(s)
      Lili Quan, Ryuichi Ohgaki, Suguru Okuda, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第135回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-18K06931
  • [Presentation] PEPT1-targeted boron delivery for boron neutron capture therapy using BPA-containing dipeptide2019

    • Author(s)
      Junji Miyabe, Ryuichi Ohgaki, Keijiro Saito, Ling Wei, Lili Quan, Chunhuan Jin, Xingming Liu, Suguru Okuda, Shushi Nagamori, Hiroshi Ohki, Kazuo Yoshino, Hidenori Inohara, Yoshikatsu Kanai
    • Organizer
      第92回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-18K19429
  • [Presentation] 腫瘍間質血管内皮細胞に発現するアミノ酸トランスポーターLAT1の阻害による血管新生抑制効果2019

    • Author(s)
      全 麗麗、大垣 隆一、奥田 傑、永森 収志、遠藤 仁、金井 好克
    • Organizer
      第92回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-18K06931
  • [Presentation] Identification of miRNA regulating the expression of cancer-type amino acid transporter LAT1: its potential as an antionco-miRNA2019

    • Author(s)
      劉 星明, 大垣 隆一, 岡西 広樹, 奥田 傑, 金井 好克
    • Organizer
      第136回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-19H03407
  • [Presentation] Effect of five amino acids stimulation on mTORC1 signaling pathway in HEK293T cells2018

    • Author(s)
      Xuhao Huang, Chunhuan Jin, Ryuichi Ohgaki, Suguru Okuda, Yoshikatsu Kanai
    • Organizer
      Campus Asia Program Faculty meeting, Symopsium and Workshop
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] 腫瘍血管新生に寄与する血管内皮細胞のアミノ酸トランスポーター2018

    • Author(s)
      大垣隆一、Quan Lili、奥田傑、永森收志、金井好克
    • Organizer
      第1回 がんと代謝研究会・若手の会
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] 腫瘍血管新生に寄与する血管内皮細胞のアミノ酸トランスポーター2018

    • Author(s)
      大垣隆一、Quan Lili、奥田傑、永森收志、金井好克
    • Organizer
      第1回 がんと代謝研究会・若手の会
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] L-type amino acid transporter 1 (LAT1) in endothelial cells of tumor vessels contributes to tumor angiogenesis2018

    • Author(s)
      Lili Quan, Ryuichi Ohgaki, Suguru Okuda, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      18th World congress of basic and clinical pharmacology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06931
  • [Presentation] Upregulation of an amino acid transporter LAT1 in tumour-associated blood vessels and its contribution to angiogenesis2018

    • Author(s)
      Ryuichi Ohgaki
    • Organizer
      Australia Japan Medical Research Symposium September 2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06931
  • [Presentation] アミノ酸トランスポーターを介した代謝制御と細胞機能制御2018

    • Author(s)
      大垣隆一、金井好克
    • Organizer
      第72回 日本栄養・食糧学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K06931
  • [Presentation] ペプチドトランスポーターを標的としたホウ素中性子捕捉療法に用いる新規ペプチド型ホウ素化合物の検討2018

    • Author(s)
      宮部淳二、大垣隆一、齋藤桂似郎、Wei Ling、奥田傑、永森收志、大木寛、吉野和夫、猪原秀典、金井好克
    • Organizer
      第133回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-18K19429
  • [Presentation] 血管内皮細胞におけるアミノ酸トランスポーターLAT1の発現と腫瘍血管新生への寄与2018

    • Author(s)
      大垣隆一
    • Organizer
      第13回 トランスポーター研究会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K06931
  • [Presentation] Construction of Flp-in 3T3 cell line stably express mLAT1 fused with AcGFP2018

    • Author(s)
      Hanbing Liu, Lili Quan, Ryuichi Ohgaki, Suguru Okuda, Yoshikatsu Kanai
    • Organizer
      Campus Asia Program Faculty meeting, Symopsium and Workshop
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] Combination of amino acids necessary and sufficient for the optimal activation of mTORC12018

    • Author(s)
      Ryuichi Ohgaki, Chunhuan Jin, Suguru Okuda, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      18th World congress of basic and clinical pharmacology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19429
  • [Presentation] アミノ酸トランスポーターを介した代謝制御と細胞機能制御2018

    • Author(s)
      大垣隆一、金井好克
    • Organizer
      第72回 日本栄養・食糧学会大会
    • Data Source
      KAKENHI-PROJECT-18K19429
  • [Presentation] Phosphoproteome analysis reveals novel cellular responses affect by inhibition of LAT1, a cancer type amino acid transporter.2018

    • Author(s)
      Pornparn Kongpracha, Shushi Nagamori, Pattama Wiriyasermkul, Suguru Okuda, Ryuichi Ohgaki, Yoshikatsu Kanai
    • Organizer
      18th World congress of basic and clinical pharmacology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19429
  • [Presentation] BPA-dipeptides, novel boron delivery agents for boron neutron capture therapy, targeting the oligopeptide transporters2018

    • Author(s)
      Junji Miyabe, Ryuichi Ohgaki, Keijiro Saito, Ling Wei, Suguru Okuda, Shushi Nagamori, Kazuo Yoshino, Hidenori Inohara, Yoshikatsu Kanai
    • Organizer
      大阪大学医学系研究フォーラム 第10回若手研究フォーラム
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] BPA-dipeptides, novel boron delivery agents for boron neutron capture therapy, are transported by oligopeptide transporter2018

    • Author(s)
      Junji Miyabe, Ryuichi Ohgaki, Keijiro Saito, Ling Wei, Suguru Okuda, Shushi Nagamori, Hiroshi Ohki, Kazuo Yoshino, Hidenori Inohara, Yoshikatsu Kanai
    • Organizer
      18th World congress of basic and clinical pharmacology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19429
  • [Presentation] Non-competitive LAT1 inhibitors suppress mTORC1 signaling similary to competitive LAT1 inhibitors2017

    • Author(s)
      Pornparn Kongpracha, Suguru Okuda, Ryuichi Ohgaki, Yoshikatsu Kanai, Shushi Nagamori
    • Organizer
      第132回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] Structure-activity relations of aromatic amino acid derivatives to interact with organic anion transporter OAT1 reveal critical moieties for renal accumulation of tumor imaging probes2017

    • Author(s)
      Chunhuan Jin, Ling Wei, Ryuichi Ohgaki, Hideyuki Tominaga, Suguru Okuda, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      大阪大学医学系研究フォーラム 第10回若手研究フォーラム
    • Data Source
      KAKENHI-PROJECT-15K08274
  • [Presentation] アミノ酸トランスポーターLAT1は膜融合関連因子4F2hcの細胞膜提示による胎盤合胞体性栄養膜の形成に必須である2017

    • Author(s)
      大垣隆一、大森崇弘、原早織、中込咲綾、金井正美、兼田(中島)加珠子、奥田傑、永森收志、金井好克
    • Organizer
      第12回 トランスポーター研究会
    • Data Source
      KAKENHI-PROJECT-15K08274
  • [Presentation] Non-competitive LAT1 inhibitors suppress mTORC1 signaling similary to competitive LAT1 inhibitors2017

    • Author(s)
      Pornparn Kongpracha, Suguru Okuda, Ryuichi Ohgaki, Yoshikatsu Kanai, Shushi Nagamori
    • Organizer
      第132回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-15K08274
  • [Presentation] Structure-activity relationship of novel inhibitors for cancer type amino acid transporter LAT12017

    • Author(s)
      Pornparn Kongpracha, Pattama Wiriyasermkul,Kazuko Kaneda-Nakashima, Suguru Okuda, Ryuichi Ohgaki, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第131回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-15K08274
  • [Presentation] LAT1 in endothelial cells as a novel target of anti-angiogenic cancer therapy2017

    • Author(s)
      Lili Quan, Ryuichi Ohgaki, Suguru Okuda, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第132回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] SGLT2阻害薬カナグリフロジンによる腎刷子縁膜タンパク質の発現変動の網羅的定量プロテオミクスを用いた解析2017

    • Author(s)
      永森收志、齊藤隆太、五十棲規嘉、栗山千亜紀、塩谷正治、大垣隆一、奥田傑、 金井好克
    • Organizer
      第60回 日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-15K08274
  • [Presentation] SGLT2阻害薬カナグリフロジンのヒトSGLT1およびSGLT2に対する作用キネティクスと阻害メカニズムの検討2017

    • Author(s)
      大垣隆一、Ling Wei、山田和徳、原大樹、栗山千亜紀、奥田傑、植田喜一郎、Laurent Leclercq、Rao N.V.S. Mamidi、塩谷正治、永森收志、金井好克
    • Organizer
      第90回 日本薬理学会年会
    • Place of Presentation
      長崎
    • Year and Date
      2017-03-14
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] Phosphoproteomics reveals the cellular processes affected by leucine transported through LAT1, a cancer type amino acid transporter2017

    • Author(s)
      Pornparn Kongpracha, Pattama Wiriyasermkul,, Suguru Okuda, Ryuichi Ohgaki, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      日本プロテオーム学会2017年大会 JHUPO 第15回大会
    • Data Source
      KAKENHI-PROJECT-15K08274
  • [Presentation] アミノ酸トランスポーターLAT1によるロイシン誘導体の認識とmTORC1シグナル活性化の関係2017

    • Author(s)
      奥田傑、Pattama Wiriyasermkul、大垣隆一、永森收志、金井好克
    • Organizer
      第90回 日本薬理学会年会
    • Place of Presentation
      長崎
    • Year and Date
      2017-03-15
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] A C-terminus mutation of SLC7A9 amino acid transporter retains substrate binding but diminishes the transport activity.2017

    • Author(s)
      Nagamori S, Kawamoto Y, Wiriyasermkul P, Nakagomi S, Okuda S, Ohgaki R, Kanai Y.
    • Organizer
      Gordon Research Conference: Mechanisms of Membrane Transport
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] アミノ酸トランスポーターLAT1によるロイシン誘導体の認識とmTORC1シグナル活性化の関係2017

    • Author(s)
      奥田傑、Pattama Wiriyasermkul、大垣隆一、永森收志、金井好克
    • Organizer
      第90回 日本薬理学会年会
    • Place of Presentation
      長崎
    • Year and Date
      2017-03-14
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] Critical moieties of aromatic amino acid for renal accumulation of tumor imaging probes2017

    • Author(s)
      Chunhuan Jin, Ling Wei, Ryuichi Ohgaki, Hideyuki Tominaga, Suguru Okuda, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第132回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] SGLT2阻害薬カナグリフロジンのヒトSGLT1およびSGLT2に対する作用キネティクスと阻害メカニズムの検討2017

    • Author(s)
      大垣隆一、Ling Wei、山田和徳、原大樹、栗山千亜紀、奥田傑、植田喜一郎、Laurent Leclercq、Rao N.V.S. Mamidi、塩谷正治、永森收志、金井好克
    • Organizer
      第90回 日本薬理学会年会
    • Place of Presentation
      長崎
    • Year and Date
      2017-03-14
    • Data Source
      KAKENHI-PROJECT-15K15053
  • [Presentation] A C-terminus mutation of SLC7A9 amino acid transporter retains substrate binding but diminishes the transport activity.2017

    • Author(s)
      Nagamori S, Kawamoto Y, Wiriyasermkul P, Nakagomi S, Okuda S, Ohgaki R, Kanai Y.
    • Organizer
      Gordon Research Conference: Mechanisms of Membrane Transport
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] 有機アニオントランスポーターOAT1に対する芳香族アミノ酸誘導体の構造活性相関:イメージングプローブの腎臓におけるバックグラウンド集積を誘起する分子内構造の同定2017

    • Author(s)
      魏玲、大垣隆一、富永英之、兼田加珠子、奥田傑、永森收志、金井好克
    • Organizer
      第90回 日本薬理学会年会
    • Place of Presentation
      長崎
    • Year and Date
      2017-03-15
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] Phosphoproteomics reveals the cellular processes affected by leucine transported through LAT1, a cancer type amino acid transporter2017

    • Author(s)
      Pornparn Kongpracha, Pattama Wiriyasermkul, Suguru Okuda, Ryuichi Ohgaki, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      日本プロテオーム学会2017年大会 JHUPO 第15回大会
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] LAT1 in endothelial cells as a novel target of anti-angiogenic cancer therapy2017

    • Author(s)
      Lili Quan, Ryuichi Ohgaki, Suguru Okuda, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第132回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] 有機アニオントランスポーターOAT1に対する芳香族アミノ酸誘導体の構造活性相関:イメージングプローブの腎臓におけるバックグラウンド集積を誘起する分子内構造の同定2017

    • Author(s)
      魏玲、大垣隆一、富永英之、兼田加珠子、奥田傑、永森收志、金井好克
    • Organizer
      第90回 日本薬理学会年会
    • Place of Presentation
      長崎
    • Year and Date
      2017-03-14
    • Data Source
      KAKENHI-PROJECT-15K15053
  • [Presentation] Structure-activity relationship of novel inhibitors for cancer type amino acid transporter LAT12017

    • Author(s)
      Pornparn Kongpracha, Pattama Wiriyasermkul,Kazuko Kaneda-Nakashima, Suguru Okuda, Ryuichi Ohgaki, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第131回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] Critical moieties of aromatic amino acid for renal accumulation of tumor imaging probes2017

    • Author(s)
      Chunhuan Jin, Ling Wei, Ryuichi Ohgaki, Hideyuki Tominaga, Suguru Okuda, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第132回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] SGLT2阻害薬カナグリフロジンのヒトSGLT1およびSGLT2に対する作用キネティクスと阻害メカニズムの検討2017

    • Author(s)
      大垣隆一、Ling Wei、山田和徳、原大樹、栗山千亜紀、奥田傑、植田喜一郎、Laurent Leclercq、Rao N.V.S. Mamidi、塩谷正治、永森收志、金井好克
    • Organizer
      第90回 日本薬理学会年会
    • Place of Presentation
      長崎
    • Year and Date
      2017-03-15
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] アミノ酸トランスポーターLAT1は膜融合関連因子4F2hcの細胞膜提示による胎盤合胞体性栄養膜の形成に必須である2017

    • Author(s)
      大垣隆一、大森崇弘、原早織 、中込咲綾 、金井正美 、兼田(中島)加珠子、奥田傑、○永森收志、金井好克
    • Organizer
      第12回 トランスポーター研究会年会
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] SGLT2阻害薬カナグリフロジンによる腎刷子縁膜タンパク質の発現変動の網羅的定量プロテオミクスを用いた解析2017

    • Author(s)
      永森收志、齊藤隆太、五十棲規嘉、栗山千亜紀、塩谷正治、大垣隆一、奥田傑、 金井好克
    • Organizer
      第60回 日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] アミノ酸トランスポーターLAT1は膜融合関連因子4F2hcの細胞膜提示による胎盤合胞体性栄養膜の形成に必須である2017

    • Author(s)
      大垣隆一、大森崇弘、原早織、中込咲綾、金井正美、兼田(中島)加珠子、奥田傑、永森收志、金井好克
    • Organizer
      第12回 トランスポーター研究会
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] Structure-activity relationship of novel inhibitors for cancer type amino acid transporter LAT12017

    • Author(s)
      Pornparn Kongpracha, Pattama Wiriyasermkul,Kazuko Kaneda-Nakashima, Suguru Okuda, Ryuichi Ohgaki, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第131回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] A C-terminus mutation of SLC7A9 amino acid transporter retains substrate binding but diminishes the transport activity.2017

    • Author(s)
      Nagamori S, Kawamoto Y, Wiriyasermkul P, Nakagomi S, Okuda S, Ohgaki R, Kanai Y.
    • Organizer
      Gordon Research Conference: Mechanisms of Membrane Transport
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08274
  • [Presentation] Structure-activity relations of aromatic amino acid derivatives to interact with organic anion transporter OAT1 reveal critical moieties for renal accumulation of tumor imaging probes2017

    • Author(s)
      Chunhuan Jin, Ling Wei, Ryuichi Ohgaki, Hideyuki Tominaga, Suguru Okuda, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      大阪大学医学系研究フォーラム 第9回若手研究フォーラム
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] Non-competitive LAT1 inhibitors suppress mTORC1 signaling similary to competitive LAT1 inhibitors2017

    • Author(s)
      Pornparn Kongpracha, Suguru Okuda, Ryuichi Ohgaki, Yoshikatsu Kanai, Shushi Nagamori
    • Organizer
      第132回 日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] アミノ酸トランスポーターLAT1によるロイシン誘導体の認識とmTORC1シグナル活性化の関係2017

    • Author(s)
      奥田傑、Pattama Wiriyasermkul、大垣隆一、永森收志、金井好克
    • Organizer
      第90回 日本薬理学会年会
    • Place of Presentation
      長崎
    • Year and Date
      2017-03-14
    • Data Source
      KAKENHI-PROJECT-15K15053
  • [Presentation] 有機アニオントランスポーターOAT1に対する芳香族アミノ酸誘導体の構造活性相関:イメージングプローブの腎臓におけるバックグラウンド集積を誘起する分子内構造の同定2017

    • Author(s)
      魏玲、大垣隆一、富永英之、兼田加珠子、奥田傑、永森收志、金井好克
    • Organizer
      第90回 日本薬理学会年会
    • Place of Presentation
      長崎
    • Year and Date
      2017-03-14
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] Phosphoproteomics reveals the cellular processes affected by leucine transported through LAT1, a cancer type amino acid transporter”.2017

    • Author(s)
      Pornparn Kongpracha, Pattama Wiriyasermkul,, Suguru Okuda, Ryuichi Ohgaki, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      日本プロテオーム学会2017年大会 JHUPO 第15回大会
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] Novel cystine transporter in renal proximal tubule identified as a “missing partner” of cystinuria-related membrane protein rBAT/SLC3A12016

    • Author(s)
      Nagamori S, Wiriyasermkul P, Espino Guarch M, Okuyama K, Nakagomi S, Okuda S, Ohgaki R, Palacin M, Kanai Y.
    • Organizer
      第25回日本尿路結石症学会
    • Place of Presentation
      千葉
    • Year and Date
      2016-07-20
    • Data Source
      KAKENHI-PROJECT-15K08274
  • [Presentation] Novel cystine transporter in renal proximal tubule identified as a “missing partner” of cystinuria-related membrane protein rBAT/SLC3A12016

    • Author(s)
      Nagamori S, Wiriyasermkul P, Espino Guarch M, Okuyama K, Nakagomi S, Okuda S, Ohgaki R, Palacin M, Kanai Y.
    • Organizer
      第26 回日本尿路結石症学会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] Inhibition kinetics, sidedness of action, and transporter-mediated uptake of the sodium/glucose cotransporter (SGLT) 2 inhibitor canagliflozin: implications for its pharmacodynamic and pharmacokinetic features2016

    • Author(s)
      Ling Wei, Ryuichi Ohgaki, Kazunori Yamada, Taiki Hara, Chiaki Kuriyama, Suguru Okuda, Kiichiro Ueta, Masaharu shiotani, Shushi Nagamori and Yoshikatsu Kanai
    • Organizer
      International and Interdisciplinary Symposium 2016 “Towards a New Era of Cardiovascular Research”
    • Place of Presentation
      東京
    • Year and Date
      2016-07-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15053
  • [Presentation] Inhibition kinetics, sidedness of action, and transporter-mediated uptake of the sodium/glucose cotransporter (SGLT) 2 inhibitor canagliflozin: implications for its pharmacodynamic and pharmacokinetic features2016

    • Author(s)
      Ohgaki R, Wei L, Yamada K, Hara T, Kuriyama C, Okuda S, Ueta K, Leclercq L, Mamidi RN, Shiotani M, Nagamori S, Kanai Y
    • Organizer
      76th American Diabetes Association Scientific Sessions
    • Place of Presentation
      New Orleans, Louisiana, US
    • Year and Date
      2016-06-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15053
  • [Presentation] Interaction of potential hepatotoxic ingredients of Traditional Chinese Medicine with liver drug transporters OATP1B1 and MDR12016

    • Author(s)
      Lili Quan,Zijie Song, Yueqing Zhou, Ryuichi Ohgaki, Shushi Nagamori, Xin He, Yoshikatsu Kanai
    • Organizer
      第63回 日本生化学会 近畿支部例会学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] Interaction of halogenated aromatic amino acid probes for tumor imaging with renal organic anion transporter OAT1: the mechanisms of renal accumulation of the imaging probes2016

    • Author(s)
      Ling Wei、大垣 隆一、富永 英之、Quan Lili、兼田(中島)加珠子、奥田 傑、永森 收志、金井 好克
    • Organizer
      第129回 日本薬理学会近畿部会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-15K15053
  • [Presentation] Novel Cystine Transporter in Renal Proximal Tubule Identied as a “Missing Partner” of Cystinuria-Related Membrane Protein rBAT/SLC3A1.2016

    • Author(s)
      Nagamori S, Wiriyasermkul P, Okuyama K, Nakagomi S, Okuda S, Ohgaki R, Kanai Y.
    • Organizer
      The Kaback Symposium
    • Place of Presentation
      Bethesda, Maryland, US
    • Year and Date
      2016-06-09
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] Interaction of potential hepatotoxic ingredients of Traditional Chinese Medicine with liver drug transporters OATP1B1 and MDR12016

    • Author(s)
      Lili Quan,Zijie Song, Yueqing Zhou, Ryuichi Ohgaki, Shushi Nagamori, Xin He, Yoshikatsu Kanai
    • Organizer
      第63回 日本生化学会 近畿支部例会学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] Inhibition kinetics, sidedness of action, and transporter-mediated uptake of the sodium/glucose cotransporter (SGLT) 2 inhibitor canagliflozin: implications for its pharmacodynamic and pharmacokinetic features2016

    • Author(s)
      Ohgaki R, Wei L, Yamada K, Hara T, Kuriyama C, Okuda S, Ueta K, Leclercq L, Mamidi RN, Shiotani M, Nagamori S, Kanai Y
    • Organizer
      76th American Diabetes Association Scientific Sessions
    • Place of Presentation
      New Orleans, Louisiana, US
    • Year and Date
      2016-06-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] Novel Cystine Transporter in Renal Proximal Tubule Identied as a “Missing Partner” of Cystinuria-Related Membrane Protein rBAT/SLC3A1.2016

    • Author(s)
      Nagamori S, Wiriyasermkul P, Okuyama K, Nakagomi S, Okuda S, Ohgaki R, Kanai Y.
    • Organizer
      Experimental Biology 2016
    • Place of Presentation
      San Diego, CA, USA
    • Year and Date
      2016-04-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15053
  • [Presentation] PEG結合リン脂質型蛍光分子プローブによる細胞膜表層pHのイメージング2016

    • Author(s)
      大垣 隆一、寺村 裕治、林 大智、永森 收志、高井 まどか、金井 好克
    • Organizer
      第129回 日本薬理学会近畿部会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-15K15053
  • [Presentation] アミノ酸トランスポーターLAT1による基質認識とmTORC1シグナル活性化に必要なロイシンの構造部位の決定2016

    • Author(s)
      奥田 傑, Pattama Wiriyasermkul, 大垣 隆一, 永森 收志, 金井 好克
    • Organizer
      第130回 日本薬理学会近畿部会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] PEG結合リン脂質型蛍光分子プローブによる細胞膜表層pHのイメージング2016

    • Author(s)
      大垣 隆一、寺村 裕治、林 大智、永森 收志、高井 まどか、金井 好克
    • Organizer
      第129回 日本薬理学会近畿部会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] PEG結合リン脂質型蛍光分子プローブの 細胞膜表層pHイメージングツールとしての有用性の検討2016

    • Author(s)
      大垣 隆一、寺村 裕治、林 大智、永森 收志、高井 まどか、金井 好克
    • Organizer
      H28年度 生理研研究会(第5回 生体界面研究会
    • Place of Presentation
      岡崎
    • Year and Date
      2016-07-04
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] Novel Cystine Transporter in Renal Proximal Tubule Identied as a “Missing Partner” of Cystinuria-Related Membrane Protein rBAT/SLC3A1.2016

    • Author(s)
      Nagamori S, Wiriyasermkul P, Okuyama K, Nakagomi S, Okuda S, Ohgaki R, Kanai Y.
    • Organizer
      The Kaback Symposium
    • Place of Presentation
      米国・メリーランド州ベセスダ
    • Year and Date
      2016-06-09
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08274
  • [Presentation] Inhibition kinetics, sidedness of action, and transporter-mediated uptake of the sodium/glucose cotransporter (SGLT) 2 inhibitor canagliflozin: implications for its pharmacodynamic and pharmacokinetic features2016

    • Author(s)
      Ohgaki R, Wei L, Yamada K, Hara T, Kuriyama C, Okuda S, Ueta K, Leclercq L, Mamidi RN, Shiotani M, Nagamori S, Kanai Y
    • Organizer
      76th American Diabetes Association Scientific Sessions
    • Place of Presentation
      New Orleans, Louisiana, US
    • Year and Date
      2016-06-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] Interaction of potential hepatotoxic ingredients of Traditional Chinese Medicine with liver drug transporters OATP1B1 and MDR12016

    • Author(s)
      Lili Quan,Zijie Song, Yueqing Zhou, Ryuichi Ohgaki, Shushi Nagamori, Xin He, Yoshikatsu Kanai
    • Organizer
      第63回 日本生化学会 近畿支部例会学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-15K15053
  • [Presentation] Novel Cystine Transporter in Renal Proximal Tubule Identied as a “Missing Partner” of Cystinuria-Related Membrane Protein rBAT/SLC3A1.2016

    • Author(s)
      3.Nagamori S, Wiriyasermkul P, Okuyama K, Nakagomi S, Okuda S, Ohgaki R, Kanai Y.
    • Organizer
      Experimental Biology 2016
    • Place of Presentation
      San Diego, CA, US
    • Year and Date
      2016-04-02
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15053
  • [Presentation] アミノ酸トランスポーターLAT1阻害によるがん転移抑制効果の検討2016

    • Author(s)
      兼田 加珠子, 魏 玲, Pornparn Kongpracha, 大垣 隆一, 永森 收志, 金井 好克
    • Organizer
      第130回 日本薬理学会近畿部会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-15K15053
  • [Presentation] PEG結合リン脂質型蛍光分子プローブの 細胞膜表層pHイメージングツールとしての有用性の検討2016

    • Author(s)
      大垣 隆一、寺村 裕治、林 大智、永森 收志、高井 まどか、金井 好克
    • Organizer
      H28年度 生理研研究会(第5回 生体界面研究会)
    • Place of Presentation
      岡崎
    • Data Source
      KAKENHI-PROJECT-15K15053
  • [Presentation] Interaction of halogenated aromatic amino acid probes for tumor imaging with renal organic anion transporter OAT1: the mechanisms of renal accumulation of the imaging probes2016

    • Author(s)
      Ling Wei、大垣 隆一、富永 英之、Quan Lili、兼田(中島)加珠子、奥田 傑、永森 收志、金井 好克
    • Organizer
      第129回 日本薬理学会近畿部会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] Interaction of halogenated aromatic amino acid probes for tumor imaging with renal organic anion transporter OAT1: the mechanisms of renal accumulation of the imaging probes2016

    • Author(s)
      Ling Wei、大垣 隆一、富永 英之、Quan Lili、兼田(中島)加珠子、奥田 傑、永森 收志、金井 好克
    • Organizer
      第129回 日本薬理学会近畿部会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] アミノ酸トランスポーターLAT1は胎盤合胞体性栄養膜の形成に必須である:膜融合関連因子4F2hcの細胞膜提示による細胞融合への寄与2016

    • Author(s)
      大垣 隆一、大森 崇弘、原 早織、中込 咲綾、金井 正美、兼田 加珠子、奥田 傑、永森 收志、金井 好克
    • Organizer
      第39回 日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-15K15053
  • [Presentation] Novel Cystine Transporter in Renal Proximal Tubule Identied as a “Missing Partner” of Cystinuria-Related Membrane Protein rBAT/SLC3A1.2016

    • Author(s)
      Nagamori S, Wiriyasermkul P, Okuyama K, Nakagomi S, Okuda S, Ohgaki R, Kanai Y.
    • Organizer
      Experimental Biology 2016
    • Place of Presentation
      San Diego, CA, US
    • Year and Date
      2016-04-01
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] Novel Cystine Transporter in Renal Proximal Tubule Identied as a “Missing Partner” of Cystinuria-Related Membrane Protein rBAT/SLC3A1.2016

    • Author(s)
      Nagamori S, Wiriyasermkul P, Okuyama K, Nakagomi S, Okuda S, Ohgaki R, Kanai Y.
    • Organizer
      The Kaback Symposium
    • Place of Presentation
      Bethesda, Maryland, US
    • Year and Date
      2016-06-09
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15053
  • [Presentation] Involvements of LRRC8A and amino acid transporter SLC proteins in the activity of volume-sensitive outwardly rectifying anion channel (VSOR)2016

    • Author(s)
      Toshiaki Okada, Ravshan Z. Sabirov, Ryuichi Ohgaki, Shushi Nagamori, Yoshikatsu Kanai, Koh Ono, Hiromi Uramoto, Yasunobu Okada
    • Organizer
      第93回 日本生理学会大会
    • Place of Presentation
      札幌
    • Year and Date
      2016-03-22
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] アミノ酸トランスポーターLAT1による基質認識とmTORC1シグナル活性化に必要なロイシンの構造部位の決定2016

    • Author(s)
      奥田 傑, Pattama Wiriyasermkul, 大垣 隆一, 永森 收志, 金井 好克
    • Organizer
      第130回 日本薬理学会近畿部会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-15K15053
  • [Presentation] アミノ酸トランスポーターLAT1阻害によるがん転移抑制効果の検討2016

    • Author(s)
      兼田 加珠子, 魏 玲, Pornparn Kongpracha, 大垣 隆一, 永森 收志, 金井 好克
    • Organizer
      第130回 日本薬理学会近畿部会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] Inhibition kinetics, sidedness of action, and transporter-mediated uptake of the sodium/glucose cotransporter (SGLT) 2 inhibitor canagliflozin: implications for its pharmacodynamic and pharmacokinetic features2016

    • Author(s)
      Ling Wei, Ryuichi Ohgaki, Kazunori Yamada, Taiki Hara, Chiaki Kuriyama, Suguru Okuda, Kiichiro Ueta, Masaharu shiotani, Shushi Nagamori and Yoshikatsu Kanai
    • Organizer
      International and Interdisciplinary Symposium 2016 “Towards a New Era of Cardiovascular Research”
    • Place of Presentation
      東京
    • Year and Date
      2016-07-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] Novel Cystine Transporter in Renal Proximal Tubule Identied as a “Missing Partner” of Cystinuria-Related Membrane Protein rBAT/SLC3A1.2016

    • Author(s)
      Nagamori S, Wiriyasermkul P, Okuyama K, Nakagomi S, Okuda S, Ohgaki R, Kanai Y.
    • Organizer
      Experimental Biology 2016
    • Place of Presentation
      San Diego, CA, USA
    • Year and Date
      2016-04-02
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] Novel Cystine Transporter in Renal Proximal Tubule Identied as a “Missing Partner” of Cystinuria-Related Membrane Protein rBAT/SLC3A1.2016

    • Author(s)
      Nagamori S, Wiriyasermkul P, Okuyama K, Nakagomi S, Okuda S, Ohgaki R, Kanai Y.
    • Organizer
      Experimental Biology 2016
    • Place of Presentation
      米国・サンディエゴ
    • Year and Date
      2016-04-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08274
  • [Presentation] Novel cystine transporter in renal proximal tubule identified as a “missing partner” of cystinuria-related membrane protein rBAT/SLC3A12016

    • Author(s)
      Nagamori S, Wiriyasermkul P, Espino Guarch M, Okuyama K, Nakagomi S, Okuda S, Ohgaki R, Palacin M, Kanai Y.
    • Organizer
      第25回 日本尿路結石症学会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-15K15053
  • [Presentation] Inhibition kinetics, sidedness of action, and transporter-mediated uptake of the sodium/glucose cotransporter (SGLT) 2 inhibitor canagliflozin: implications for its pharmacodynamic and pharmacokinetic features2016

    • Author(s)
      Ling Wei, Ryuichi Ohgaki, Kazunori Yamada, Taiki Hara, Chiaki Kuriyama, Suguru Okuda, Kiichiro Ueta, Masaharu shiotani, Shushi Nagamori and Yoshikatsu Kanai
    • Organizer
      International and Interdisciplinary Symposium 2016 “Towards a New Era of Cardiovascular Research”
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] アミノ酸トランスポーターLAT1阻害によるがん転移抑制効果の検討2016

    • Author(s)
      兼田 加珠子, 魏 玲, Pornparn Kongpracha, 大垣 隆一, 永森 收志, 金井 好克
    • Organizer
      第130回 日本薬理学会近畿部会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] アミノ酸トランスポーターLAT1による膜融合関連因子4F2hcの細胞膜提示は胎盤合胞体性栄養膜の形成に必須である2016

    • Author(s)
      大垣隆一
    • Organizer
      大阪大学医学系研究フォーラム 第7回 若手研究フォーラム
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] アミノ酸トランスポーターLAT1は胎盤合胞体性栄養膜の形成に必須である:膜融合関連因子4F2hcの細胞膜提示による細胞融合への寄与2016

    • Author(s)
      大垣 隆一、大森 崇弘、原 早織、中込 咲綾、金井 正美、兼田 加珠子、奥田 傑、永森 收志、金井 好克
    • Organizer
      第39回 日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] アミノ酸トランスポーターLAT1は胎盤合胞体性栄養膜の形成に必須である:膜融合関連因子4F2hcの細胞膜提示による細胞融合への寄与2016

    • Author(s)
      大垣 隆一、大森 崇弘、原 早織、中込 咲綾、金井 正美、兼田 加珠子、奥田 傑、永森 收志、金井 好克
    • Organizer
      第39回 日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] アミノ酸トランスポーターLAT1による基質認識とmTORC1シグナル活性化に必要なロイシンの構造部位の決定2016

    • Author(s)
      奥田 傑, Pattama Wiriyasermkul, 大垣 隆一, 永森 收志, 金井 好克
    • Organizer
      第130回 日本薬理学会近畿部会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] Properties of mTORC1 regulation by amino acid signaling in HEK293T cells2015

    • Author(s)
      大垣 隆一、永森 收志、ウィリヤサムクン パッタマ、萩原 浩平、金井 好克
    • Organizer
      第38回 日本分子生物学会年会・第88回 日本生化学会大会 合同大会 (BMB2015)
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] Transport of 3-fluoro-L-α-methyl-tyrosine (FAMT) by organic ion transporters: a possible cause of renal background in 18F-FAMT PET2015

    • Author(s)
      Wei Ling、富永 英之、Wiriyasermkul Pattama、大垣 隆一、萩原 浩平、奥田 傑、永森 收志、金井 好克
    • Organizer
      第127回 日本薬理学会近畿部会
    • Place of Presentation
      岐阜
    • Year and Date
      2015-06-26
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] アミノ酸トランスポーター阻害薬による抗腫瘍薬作用増強効果についての検討2015

    • Author(s)
      兼田加珠子、Pornparn Kongpracha、Ling Wei、大垣 隆一、 永森 收志、金井 好克
    • Organizer
      第37回 生体膜と薬物の相互作用シンポジウム
    • Place of Presentation
      熊本
    • Year and Date
      2015-11-19
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] SGLT2阻害薬カナグリフロジンのヒトSGLT2による輸送と細胞内外からの阻害作用の検討2015

    • Author(s)
      大垣隆一、Ling Wei、永森收志、山田和徳、原大樹、栗山千亜紀、植田喜一 郎、塩谷正治、金井好克
    • Organizer
      第58回日本糖尿病学会年次学術集会
    • Place of Presentation
      下関
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-15K15053
  • [Presentation] Inhibition of the LAT1-mediated leucine transport affects multiple cellular processes in pancreatic cancer cells.2015

    • Author(s)
      Pornparn Kongprach, Pattama Wiriyasermkul, Noriyoshi Isozumi, Printip Wongthai, Suguru Okuda, Kenjiro Tadagaki, Ryuichi Ohgaki, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第62回日本生化学会近畿支部例会
    • Place of Presentation
      滋賀
    • Year and Date
      2015-05-16
    • Data Source
      KAKENHI-PROJECT-15K15053
  • [Presentation] Inhibition of the LAT1-mediated leucine transport affects multiple cellular processes in pancreatic cancer cells.2015

    • Author(s)
      Pornparn Kongprach, Pattama Wiriyasermkul, Noriyoshi Isozumi, Printip Wongthai, Suguru Okuda, Kenjiro Tadagaki, Ryuichi Ohgaki, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第62回日本生化学会近畿支部例会
    • Place of Presentation
      滋賀
    • Year and Date
      2015-05-16
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] Leucine transported by a cancer-type amino acid transporter LAT1 affects multiple cellular processes in pancreatic cancer cells.2015

    • Author(s)
      Pornparn Kongpracha, Pattama Wiriyasermkul, Noriyoshi Isozumi, Kazuko Kaneda-Nakashima, Suguru Okuda, Ryuichi Ohgaki, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第38回分子生物学会年会・第88回生化学会大会合同大会(BMB2015)
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] HEK293T細胞のアミノ酸シグナルによるmTORC1活性化の特性についての検討 Properties of mTORC1 regulation by amino acid signaling in HEK293T cells2015

    • Author(s)
      大垣 隆一、永森 收志、ウィリヤサムクン パッタマ、萩原 浩平、金井 好克
    • Organizer
      第38回分子生物学会年会・第88回生化学会大会合同大会(BMB2015)
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] アミノ酸輸送体阻害薬は新規抗がん薬として有用である Inhibitor of amino acid transporter is useful as a novel anti-cancer drug2015

    • Author(s)
      兼田(中島)加珠子、疋田隼人、Pornparn Kongpracha、Ling Wei、大垣隆一、永森收志、竹原徹郎、金井好克
    • Organizer
      第38回分子生物学会年会・第88回生化学会大会合同大会(BMB2015)
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] アミノ酸輸送体阻害薬は新規抗がん薬として有用である Inhibitor of amino acid transporter is useful as a novel anti-cancer drug2015

    • Author(s)
      兼田(中島)加珠子、疋田隼人、Pornparn Kongpracha、Ling Wei、大垣隆一、 永森收志、竹原徹郎、金井好克
    • Organizer
      第38回分子生物学会年会・第88回生化学会大会合同大会(BMB2015)
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15K15053
  • [Presentation] Cellular uptake of 4-borono-L-phenylalanine, a 10B carrier of boron neutron capture therapy, depends on the expression of cancer type amino acid transporter LAT12015

    • Author(s)
      Printip Wongthai, Kohei Hagiwara, Pattama Wiriyasermkul, Noriyoshi Isozumi, Ryuichi Ohgaki, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      The 88th Annual Meeting of Japanese Pharmacological society
    • Place of Presentation
      名古屋
    • Year and Date
      2015-03-19
    • Data Source
      KAKENHI-PROJECT-24390217
  • [Presentation] Inhibitor of amino acid transporter is useful as a novel anti-cancer drug2015

    • Author(s)
      兼田(中島)加珠子、疋田隼人、Pornparn Kongpracha、Ling Wei、大垣隆一、永森收志、竹原徹郎、金井好克
    • Organizer
      第38回 日本分子生物学会年会・第88回 日本生化学会大会 合同大会 (BMB2015)
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] アミノ酸トランスポーター阻害薬による抗腫瘍薬作用増強効果についての検討2015

    • Author(s)
      兼田加珠子、Pornparn Kongpracha、Ling Wei、大垣 隆一、 永森 收志、金井 好克
    • Organizer
      第37回生体膜と薬物の相互作用シンポジウム
    • Place of Presentation
      熊本
    • Year and Date
      2015-11-19
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] アミノ酸輸送体阻害薬による抗がん剤作用増強効果についての検討2015

    • Author(s)
      兼田 加珠子、Pornparn Kongpracha、Ling Wei、大垣 隆一、永森 收志、金 井 好克
    • Organizer
      第24回日本Cell Death学会
    • Place of Presentation
      大阪
    • Year and Date
      2015-07-11
    • Data Source
      KAKENHI-PROJECT-15K15053
  • [Presentation] SGLT2阻害薬カナグリフロジンのヒトSGLT2による輸送と細胞内外からの阻害作用の検討2015

    • Author(s)
      大垣隆一、Ling Wei、永森收志、山田和徳、原大樹、栗山千亜紀、植田喜一郎、塩谷正治、金井好克
    • Organizer
      第58回日本糖尿病学会年次学術集会
    • Place of Presentation
      下関
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] HEK293T細胞のアミノ酸シグナルによるmTORC1活性化の特性についての検討 Properties of mTORC1 regulation by amino acid signaling in HEK293T cells2015

    • Author(s)
      大垣 隆一、永森 收志、ウィリヤサムクン パッタマ、萩原 浩平、金井 好克
    • Organizer
      第38回分子生物学会年会・第88回生化学会大会合同大会(BMB2015)
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K15053
  • [Presentation] 膜輸送複合体transportsome における輸送機能共役の解析 ―再構成プロテオリポソームによる実証2015

    • Author(s)
      永森收志、大垣隆一、金井好克
    • Organizer
      第2回生体界面研究会
    • Place of Presentation
      大阪
    • Year and Date
      2015-02-20
    • Data Source
      KAKENHI-PROJECT-26670123
  • [Presentation] Inhibition of the LAT1-mediated leucine transport affects multiple cellular processes in pancreatic cancer cells.2015

    • Author(s)
      Pornparn Kongprach, Pattama Wiriyasermkul, Noriyoshi Isozumi, Printip Wongthai, Suguru Okuda, Kenjiro Tadagaki, Ryuichi Ohgaki, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第62回 日本生化学会近畿支部例会
    • Place of Presentation
      滋賀
    • Year and Date
      2015-05-16
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] アミノ酸輸送体阻害薬による抗がん剤作用増強効果についての検討2015

    • Author(s)
      兼田 加珠子、Pornparn Kongpracha、Ling Wei、大垣 隆一、永森 收志、金井 好克
    • Organizer
      第24回日本Cell Death学会
    • Place of Presentation
      大阪
    • Year and Date
      2015-07-11
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] Na+/グルコース共輸送体2(SGLT2)阻害薬の作用キネティクスと阻害メカニズム2015

    • Author(s)
      大垣 隆一、Wei Ling、永森 收志、山田 和徳、原 大樹、栗山 千亜紀、植田 喜一郎、塩谷 正治、金井 好克
    • Organizer
      第128回日本薬理学会近畿部会
    • Place of Presentation
      大阪
    • Year and Date
      2015-11-20
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] アミノ酸輸送体阻害薬による抗がん剤作用増強効果についての検討2015

    • Author(s)
      兼田加珠子、Pornparn Kongpracha、Ling Wei、大垣 隆一、永森 收志、金井 好克
    • Organizer
      第24回 日本Cell Death学会
    • Place of Presentation
      大阪
    • Year and Date
      2015-07-11
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] Transport of 3-fluoro-L-α-methyl-tyrosine (FAMT) by organic ion transporters: a possible cause of renal background in 18F-FAMT PET2015

    • Author(s)
      Wei Ling、富永 英之、Wiriyasermkul Pattama、大垣 隆一、萩原浩平、奥田 傑、永森 收志、金井 好克
    • Organizer
      第127回日本薬理学会近畿部会
    • Place of Presentation
      岐阜
    • Year and Date
      2015-06-26
    • Data Source
      KAKENHI-PROJECT-15K15053
  • [Presentation] 膜輸送複合体transportsome における輸送機能共役の解析 ―再構成プロテオリポソームによる実証2015

    • Author(s)
      永森收志、大垣隆一、金井好克
    • Organizer
      第2回生体界面研究会
    • Place of Presentation
      大阪
    • Year and Date
      2015-02-20
    • Data Source
      KAKENHI-PROJECT-24390217
  • [Presentation] 3-fluoro-L-alpha-methyltyrosine (FAMT) PETにおける18F-FAMTの腎臓集積の分子機序の解明2015

    • Author(s)
      Ling Wei, Hideyuki Tominaka, Pattama Wiriyasermkul, Ryuichi Ohgaki, Kohei Hagiwara, Suguru Okuda, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第88回 日本薬理学会年会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-03-18
    • Data Source
      KAKENHI-PROJECT-24390217
  • [Presentation] 1.Suppression of cancer-type amino acid transporter LAT1 affects multiple cellular events in pancreatic cancer cells2015

    • Author(s)
      Pornparn Kongpracha, Pattama Wiriyasermkul, Noriyoshi Isozumi, Printip Wongthai, Kazuko Kaneda-Nakashima, Suguru Okuda, Ryuichi Ohgaki, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      The 88th Annual Meeting of Japanese Pharmacological society
    • Place of Presentation
      名古屋
    • Year and Date
      2015-03-19
    • Data Source
      KAKENHI-PROJECT-24390217
  • [Presentation] アミノ酸トランスポーター阻害薬による抗腫瘍薬作用増強効果についての検討2015

    • Author(s)
      兼田加珠子、Pornparn Kongpracha、Ling Wei、大垣 隆一、 永森 收志、金 井 好克
    • Organizer
      第37回生体膜と薬物の相互作用シンポジウム
    • Place of Presentation
      熊本
    • Year and Date
      2015-11-19
    • Data Source
      KAKENHI-PROJECT-15K15053
  • [Presentation] Leucine transported by a cancer-type amino acid transporter LAT1 affects multiple cellular processes in pancreatic cancer cells.2015

    • Author(s)
      Pornparn Kongpracha, Pattama Wiriyasermkul, Noriyoshi Isozumi, Kazuko Kaneda-Nakashima, Suguru Okuda, Ryuichi Ohgaki, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第38回 日本分子生物学会年会・第88回 日本生化学会大会 合同大会 (BMB2015)
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15K08273
  • [Presentation] Na+/グルコース共輸送体2(SGLT2)阻害薬の作用キネティクスと阻害メカニズム2015

    • Author(s)
      大垣 隆一、Wei Ling、永森 收志、山田 和徳、原 大樹、栗山 千亜紀、植田 喜一郎、塩谷 正治、金井 好克
    • Organizer
      第128回日本薬理学会近畿部会
    • Place of Presentation
      大阪
    • Year and Date
      2015-11-20
    • Data Source
      KAKENHI-PROJECT-15K15053
  • [Presentation] Leucine transported by a cancer-type amino acid transporter LAT1 affects multiple cellular processes in pancreatic cancer cells.2015

    • Author(s)
      Pornparn Kongpracha, Pattama Wiriyasermkul, Noriyoshi Isozumi, Kazuko Kaneda-Nakashima, Suguru Okuda, Ryuichi Ohgaki, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第38回分子生物学会年会・第88回生化学会大会合同大会(BMB2015)
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15K15053
  • [Presentation] Transport of 3-fluoro-L-α-methyl-tyrosine (FAMT) by organic ion transporters: a possible cause of renal background in 18F-FAMT PET2015

    • Author(s)
      Wei Ling、富永 英之、Wiriyasermkul Pattama、大垣 隆一、萩原浩平、奥田傑、永森 收志、金井 好克
    • Organizer
      第127回日本薬理学会近畿部会
    • Place of Presentation
      岐阜
    • Year and Date
      2015-06-26
    • Data Source
      KAKENHI-PROJECT-15H04685
  • [Presentation] Inhibition of cancer-type amino acid transporter LAT1 affects multiple cellular events in pancreatic cancer cells2014

    • Author(s)
      Pornparn Kongprach, Pattama Wiriyasermkul, Noriyoshi Isozumi, Printip Wongthai, Suguru Okuda, Kenjiro Tadagaki, Ryuichi Ohgaki, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      The 87th Meeting of Japanese Pharmacological Society Kinki Branch
    • Place of Presentation
      和歌山
    • Year and Date
      2014-10-24
    • Data Source
      KAKENHI-PROJECT-24390217
  • [Presentation] Study of a cellular signaling network stimulated with leucine transported by a cancer-type amino acid transporter LAT1.2014

    • Author(s)
      Pornparn Kongprach, Pattama Wiriyasermkul, Noriyoshi Isozumi, Printip Wongthai, Suguru Okuda, Kenjiro Tadagaki, Ryuichi Ohgaki, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      The 61th Japanese Biochemical Society Kinki Branch
    • Place of Presentation
      京都
    • Year and Date
      2014-05-17
    • Data Source
      KAKENHI-PROJECT-24390217
  • [Presentation] Transport of 3-fluoro-L-alpha-methyltyrosine (FAMT) by amino acid transports and organic ion transporters explains cancer-specificity and renal background in 18F-FAMT PET2014

    • Author(s)
      Ling Wei, 富永 英之, Pattama Wiriyasermkul, 大垣 隆一, 萩原 浩平, 永森 收志, 金井 好克
    • Organizer
      th Asia Pacific ISSX Meeting 2014
    • Place of Presentation
      天津・中国
    • Year and Date
      2014-05-10
    • Data Source
      KAKENHI-PROJECT-24390217
  • [Presentation] A novel cystine transporter in S3 segment of the renal proximal tubule is an “unknown-partner” of Slc3a1 (rBAT).2013

    • Author(s)
      Shushi Nagamori, Pattama Wiriyasermkul, Meritxell Espino Guarch, Kazuhisa Okuyama, Saya Nakagomi, Kenijiro Tadagaki, Kazuaki Takafuji, Ryuichi Ohgaki, Manuel Palacín, Yoshikatsu Kanai
    • Organizer
      2nd HDP international symposium on Multi-Level Systems Biology
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24659116
  • [Presentation] Involvement of amino acid transporter in vascular endothelial cell tube formation.2013

    • Author(s)
      Saori Hara, Ryuichi Ohgaki, Printip Wongthai, Saya Nakagomi, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      生理学研究所研究会「細胞センサーの分子機構・相互関連・ネットワーク研究会」
    • Place of Presentation
      岡崎
    • Data Source
      KAKENHI-PROJECT-25870403
  • [Presentation] Involvement of amino acid transporter in vascular endothelial cell tube formation2013

    • Author(s)
      ○Saori Hara, Ryuichi Ohgaki, Printip Wongthai, Saya Nakagomi, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      生理学研究所研究会「細胞センサーの分子機構・相互関連・ネットワーク研究会」
    • Place of Presentation
      岡崎
    • Data Source
      KAKENHI-PROJECT-24390217
  • [Presentation] Age-dependent maintenance of transportsome in C. elegans2013

    • Author(s)
      ○Kohei Hagiwara, Shushi Nagamori, Yasuhiro M. Umemura, Ryuichi Ohgaki, Yoshikatsu Kanai
    • Organizer
      First Awaji International Workshop on “Electron Spin Science & Technology: Biological and Materials Science Oriented Applications”
    • Place of Presentation
      Awaji
    • Data Source
      KAKENHI-PROJECT-24390217
  • [Presentation] Midgestational lethality in mice lacking LAT1, large neutral amino acid transporter 1, is associated with abnormal blood vessel formation and defective placental development.2013

    • Author(s)
      大垣 隆一、李 悦、原 沙織、中込 紗綾、永森 收志、金井 好克
    • Organizer
      第86回日本生化学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24659116
  • [Presentation] A novel cystine transporter in S3 segment of the renal proximal tubule is an “unknown-partner” of Slc3a1 (rBAT)2013

    • Author(s)
      ○Shushi Nagamori, Pattama Wiriyasermkul, Meritxell Espino Guarch, Kazuhisa Okuyama, Saya Nakagomi, Kenijiro Tadagaki, Kazuaki Takafuji, Ryuichi Ohgaki, Manuel Palacin, Yoshikatsu Kanai
    • Organizer
      2nd HDP international symposium on Multi-Level Systems Biology
    • Place of Presentation
      Tokyo, Japan
    • Data Source
      KAKENHI-PROJECT-24390217
  • [Presentation] A novel cystine transporter in S3 segment of the renal proximal tubule is an “unknown-partner” of Slc3a1 (rBAT)2013

    • Author(s)
      Shushi Nagamori, Pattama Wiriyasermkul, Meritxell Espino Guarch, Kazuhisa Okuyama, Saya Nakagomi, Kenijiro Tadagaki, Kazuaki Takafuji, Ryuichi Ohgaki, Manuel Palacín, Yoshikatsu Kanai
    • Organizer
      2nd HDP international symposium on Multi-Level Systems Biology
    • Place of Presentation
      Marunouchi, Tokyo
    • Data Source
      KAKENHI-PROJECT-24591198
  • [Presentation] 線虫腸管細胞におけるアミノ酸トランスポーターAAT-6の頂端膜局在に寄与するトランスポートソーム.2013

    • Author(s)
      村田 大輔、大垣 隆一、萩原 浩平、Kanokporn Phetdee、永森 收志、平田 拓、野村 和子、野村 一也、三谷 昌平、金井 好克
    • Organizer
      第8回トランスポーター研究会年会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-25870403
  • [Presentation] Involvement of amino acid transporter in vascular endothelial cell tube formation.2013

    • Author(s)
      Saori Hara, Ryuichi Ohgaki, Printip Wongthai, Saya Nakagomi, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      生理学研究所研究会「細胞センサーの分子機構・相互関連・ネットワーク研究会」
    • Place of Presentation
      岡崎
    • Data Source
      KAKENHI-PROJECT-24659116
  • [Presentation] Expression and functional profiles of amino acid transporters in cancer cell lines2013

    • Author(s)
      Pattama Wiriyasermkul, Shushi Nagamori, Noriyoshi Isozumi, Ryuichi Ohgaki, Hideyuki Tominaga and Yoshikatsu Kanai
    • Organizer
      第86回日本生化学会
    • Place of Presentation
      横浜
    • Year and Date
      2013-09-12
    • Data Source
      KAKENHI-PROJECT-24659116
  • [Presentation] Expression and functional profiles of amino acid transporters in cancer cell lines.2013

    • Author(s)
      Pattama Wiriyasermkul, Shushi Nagamori, Noriyoshi Isozumi, Ryuichi Ohgaki, Hideyuki Tominaga and Yoshikatsu Kanai
    • Organizer
      第86回日本生化学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24659116
  • [Presentation] Age-dependent maintenance of transportsome in C. elegans.2013

    • Author(s)
      Kohei Hagiwara, Shushi Nagamori, Yasuhiro M. Umemura, Ryuichi Ohgaki, Yoshikatsu Kanai
    • Organizer
      第1回 Awaji International Workshop on “Electron Spin Science & Technology: Biological and Materials Science Oriented Applications
    • Place of Presentation
      淡路
    • Data Source
      KAKENHI-PROJECT-24659116
  • [Presentation] Age-dependent maintenance of transportsome in C. elegans.2013

    • Author(s)
      Kohei Hagiwara, Shushi Nagamori, Yasuhiro M. Umemura, Ryuichi Ohgaki, Yoshikatsu Kanai
    • Organizer
      第1回 Awaji International Workshop on “Electron Spin Science & Technology: Biological and Materials Science Oriented Applications
    • Place of Presentation
      淡路
    • Data Source
      KAKENHI-PROJECT-25870403
  • [Presentation] Midgestational lethality in mice lacking LAT1, large neutral amino acid transporter 1, is associated with abnormal blood vessel formation and defective placental development2013

    • Author(s)
      ○大垣 隆一、李 悦、原 沙織、中込 紗綾、永森 收志、金井 好克
    • Organizer
      第86回日本生化学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24390217
  • [Presentation] A novel cystine transporter in S3 segment of the renal proximal tubule is an “unknown-partner” of Slc3a1 (rBAT).2013

    • Author(s)
      Shushi Nagamori, Pattama Wiriyasermkul, Meritxell Espino Guarch, Kazuhisa Okuyama, Saya Nakagomi, Kenijiro Tadagaki, Kazuaki Takafuji, Ryuichi Ohgaki, Manuel Palacin, Yoshikatsu Kanai
    • Organizer
      2nd HDP international symposium on Multi-Level Systems Biology
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25870403
  • [Presentation] Boronophenylalanine;a rational carrier for 10B for BNCT, is transportsd by both LAT1 and LAT2.2013

    • Author(s)
      Printip Wongthai, Pattama Wiriyasermkul, Yumiko Nishinaka, Ryuichi Ohgaki, Ker!jiro Tadagaki, Shushi Nagamori, Yoshikatsu Kanai.
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡市
    • Year and Date
      2013-03-23
    • Data Source
      KAKENHI-PROJECT-24390217
  • [Presentation] Kinetic analysis of 3F-L-a-methyltyrosine (FAMT) transport by L-type amino acid transporter 12013

    • Author(s)
      Ling Wei, Hideyuki Tominaka, Pattama Wiriyasermkul, Yumiko Nishinaka, Ryuichi Ohgaki, Kenjiro Tadagaki, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡市
    • Year and Date
      2013-03-23
    • Data Source
      KAKENHI-PROJECT-24390217
  • [Presentation] Midgestational lethality in mice lacking LAT1, large neutral amino acid transporter 1, is associated with abnormal blood vessel formation and defective placental development.2013

    • Author(s)
      大垣 隆一、李 悦、原 沙織、中込 紗綾、永森 收志、金井 好克
    • Organizer
      第86回日本生化学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-25870403
  • [Presentation] 腎近位尿細管の第二のシスチントランスポーターの分子同定と機能解析2012

    • Author(s)
      永森收志, 奥山裕久, Pattama Wiriyasermkul, 中込咲綾, 西中由美子, 高藤和輝, 大垣隆一, 金井好克
    • Organizer
      2012年度 生理研研究会
    • Place of Presentation
      愛知、日本
    • Year and Date
      2012-12-01
    • Data Source
      KAKENHI-PROJECT-23790334
  • [Presentation] 腎尿細管に残された第二のシスチントランスポーターの分子同定2012

    • Author(s)
      大垣隆一, 奥山裕久, Pattama Wiriyasermkul, 中込咲綾, 西中由美子, 高藤和輝, 永森收志, 金井好克.
    • Organizer
      第3回分子腎臓フォーラム
    • Place of Presentation
      東京、日本
    • Year and Date
      2012-09-01
    • Data Source
      KAKENHI-PROJECT-23790334
  • [Presentation] Functional coupling between a Na+-dependent anion transporter SMCT2 and a urate-anion exchanger URAT1 through a scaffold protein PDZK12012

    • Author(s)
      Nagamori S, Umemura Y, Wiriyasermkul P, Nakagomi S, Nishinaka Y, Takafuji K, Ohgaki R, Kanai Y
    • Organizer
      Gordon Research Conferences Membrane Transport Proteins
    • Place of Presentation
      Les Diablerets, Switzerland.
    • Data Source
      KAKENHI-PROJECT-23790334
  • [Presentation] 表皮バリア形成に必須の新規リパーゼ様タンパク質mYEH2の役割. 花王芸術科学財団2012

    • Author(s)
      大垣隆一
    • Organizer
      第14回 助成研究発表・交流会
    • Place of Presentation
      東京、日本
    • Year and Date
      2012-06-06
    • Data Source
      KAKENHI-PROJECT-23790334
  • [Presentation] Functional coupling between a Na+-dependent anion transporter SMCT2 and a urate-anion exchanger URAT1 through a scaffold protein PDZK2012

    • Author(s)
      Shushi Nagamori, Yasuhiro Umemura, Pattama Wiriyasermkul, Saya Nakagomi, Yumiko Nishinaka, Kazuaki Takafuji, Ryuichi Ohgaki, Yoshikatsu Kanai.
    • Organizer
      Gordon Research Conferences, Membrane Transport Proteins.
    • Place of Presentation
      Les Diablerets, Switzerland
    • Data Source
      KAKENHI-PROJECT-24390217
  • [Presentation] ニコチンによる海馬神経細胞スパインの形態変化(3)2012

    • Author(s)
      田中秀和、Pattama Wiriyasermkul、忠垣憲次郎、大垣隆一、永森收志、金井好克
    • Organizer
      第122回日本薬理学会近畿部会
    • Place of Presentation
      豊中市
    • Year and Date
      2012-11-16
    • Data Source
      KAKENHI-PROJECT-23790334
  • [Presentation] Functional coupling between a Na+-dependent anion transporter SMCT2 and a urate-anion exchanger URAT1 through a scaffold protein PDZK1.2012

    • Author(s)
      Shushi Nagamori, Yasuhiro Umemura, Pattama Wiriyasermkul, Saya Nakagomi, Yumiko Nishinaka, Kazuaki Takafuji, Ryuichi Ohgaki, Yoshikatsu Kanai.
    • Organizer
      Gordon Research Conferences, Membrane Transport Proteins.
    • Place of Presentation
      Les Diablerets, Switzerland
    • Data Source
      KAKENHI-PROJECT-24591198
  • [Presentation] 特異プロスタグランジン輸送体OAT -PGノックアウトマウスの食塩応答性血圧変動の機序の解明2012

    • Author(s)
      金井好克, 永森收志, 大垣隆一, 中込咲綾, Wiriyasermkul Pattama, 西山俊.腎
    • Organizer
      ソルト・サイエンス研究財団「第24回助成研究発表会」
    • Place of Presentation
      東京
    • Year and Date
      2012-07-18
    • Data Source
      KAKENHI-PROJECT-23790334
  • [Presentation] 質量分析計と再構成プロテオリポソームを用いた新規トランスポーター複合体の解析-腎尿細管に残された第二のシスチントランスポーターの分子同定2012

    • Author(s)
      永森收志, 奥山裕久, Pattama,Wiriyasermkul, 中込咲綾, 西中由美子, 高藤和輝, 大垣隆一, 金井好克
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡、日本
    • Year and Date
      2012-12-15
    • Data Source
      KAKENHI-PROJECT-23790334
  • [Presentation] 腎尿細管に残された第二のシスチントランスポーターの分子同定2012

    • Author(s)
      大垣隆一,奥山裕久, Pattama Wiriyasermkul,中込咲綾,西中由美子,高藤和輝,永森牧志,金井好克.
    • Organizer
      第3回分子腎臓フォーラム
    • Place of Presentation
      東京
    • Year and Date
      2012-09-01
    • Data Source
      KAKENHI-PROJECT-24390217
  • [Presentation] Functional coupling between a Na+-dependent anion transporter SMCT2 and a urate-anion exchanger URAT1 through a scaffold protein PDZK1.2012

    • Author(s)
      Nagamori S, Umemura Y, Wiriyasermkul P, Nakagomi S, Nishinaka Y, Takafuji K, Ohgaki R, Kanai Y.
    • Organizer
      Gordon Research Conferences, Membrane Transport Proteins.
    • Place of Presentation
      Les Diablerets, Switzerland
    • Data Source
      KAKENHI-PROJECT-23790334
  • [Presentation] 質量分析計と再構成プロテオリボソームを用いた新規トランスポーター複合体の解析-腎尿細管に残された第二のシスチントランスポーターの分子同定2012

    • Author(s)
      永森收志、奥山裕久、PattamaWiriyasermkul、中込咲綾、西中由美子、高藤和輝、大垣隆一、金井好克
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡市
    • Year and Date
      2012-12-15
    • Data Source
      KAKENHI-PROJECT-24390217
  • [Presentation] 腎近位尿細管の第二のシスチントランスポーターの分子同定と機能解析2012

    • Author(s)
      永森收志、奥山裕久、PattamaWiriyasermkul、中込咲綾、西中由美子、高藤和輝、大垣隆一、金井好克
    • Organizer
      2012年度生理研研究会『粘膜防御における上皮膜輸送の役割とその破綻による疾病発症メカニズム』
    • Place of Presentation
      岡崎市
    • Year and Date
      2012-12-01
    • Data Source
      KAKENHI-PROJECT-24390217
  • [Presentation] System L amino acid transporter LAT1 is essential for embryonic angiogenesis2011

    • Author(s)
      大垣隆一、Li Yuewei、永森收志、田中秀和、金井好克
    • Organizer
      第84回 日本生化学会大会
    • Place of Presentation
      京都国際会館
    • Data Source
      KAKENHI-PROJECT-23790334
  • [Presentation] System L amino acid transporter LAT1 is essential for embryonic angiogenesis2011

    • Author(s)
      大垣隆一, Li Yuewei, 永森收志, 田中秀和, 金井好克
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      日本、京都.
    • Year and Date
      2011-09-22
    • Data Source
      KAKENHI-PROJECT-23790334
  • [Presentation] The structural requirements of leucine derivatives to be transported by L-type amino acid transporter 1 (LAT1) and to activate mammalian target of rapamycin (mTOR)2010

    • Author(s)
      P.Wiriyasermkul, 永森収志、木村徹、大垣隆一、金井好克
    • Organizer
      第118回日本薬理学会近畿部会
    • Place of Presentation
      大阪府・豊中市
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-22659052
  • [Presentation] The structural requirements of leucine derivatives to interact with L-type aminoacid transporter 1 (LAT1) and to activate mammalian target of rapamycin (mTOR)2010

    • Author(s)
      Pattama Wiriyasermkul、永森收志、木村徹、大垣隆一、金井好克, 外
    • Organizer
      Biochemistry and Molecular Biology 2010
    • Place of Presentation
      神戸市
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-21390264
  • [Presentation] The structural requirements of leucine derivatives to interact with L-type aminoacid transporter 1 (LAT1) and to activate mammalian target of rapamycin (mTOR)2010

    • Author(s)
      Pattama Wiriyasermkul、永森収志、木村徹、大垣隆一、金井好克, 外
    • Organizer
      Biochemistry and Molecular Biology 2010
    • Place of Presentation
      神戸市
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-22659052
  • [Presentation] The structural requirements of leucine derivatives to be transported by L-type aminoacid transporter 1 (LAT1) and to activate mammalian target of rapamycin (mTOR)2010

    • Author(s)
      P.Wiriyasermkul, 永森收志、木村徹、大垣隆一、金井好克
    • Organizer
      第118回日本薬理学会近畿部会
    • Place of Presentation
      大阪府・豊中市
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-21390264
  • [Presentation] SvenC.D.vanIJzendoorn、DickHoekstra、金澤浩『Na+/H+交換輸送蛋白質NHE6/SLC9A6によるエンドソームpH調節は肝細胞の極性形成維持において重要である』2010

    • Author(s)
      松下昌史、大垣隆一
    • Organizer
      BMB2010
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2010-12-09
    • Data Source
      KAKENHI-PROJECT-21370055
  • [Presentation] LAT1ノックアウトマウスの表現型解析2010

    • Author(s)
      大垣隆一、 Yuewei Li、永森収志、金井好克
    • Organizer
      日本薬理学会年会
    • Place of Presentation
      大阪
    • Year and Date
      2010-03-16
    • Data Source
      KAKENHI-PROJECT-17081016
  • [Presentation] Na^+/H^+ exchanger isoform 6 controls the development of apical bile can alicular domains in hepatic HepG2 cells2009

    • Author(s)
      大垣隆一、金澤浩、Dick Hoekstra, Sven C.D.van IJzendoorn
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸ポートアイランド
    • Data Source
      KAKENHI-PROJECT-21370055
  • [Presentation] Stimulation of amino acids to growth signal in HEK293T2009

    • Author(s)
      大垣隆一、 Narakorn Khunweeraphong, 永森収志, Taku Hirata, 金井好克
    • Organizer
      The 36th International Congress of Physiological Sciences
    • Place of Presentation
      京都
    • Year and Date
      2009-07-28
    • Data Source
      KAKENHI-PROJECT-17081016
  • [Presentation] Mechanisms of tumor cell uptake of 4-borono-phenylalanine, a 10B carrier of boron neutron capture therapy, mediated by system L amino acid transporters.

    • Author(s)
      Printip Wongthai, Kohei Hagiwara, Yurika Miyoshi, Pattama Wiriyasermkul, Pornparn Kongpracha, Isozumi Noriyoshi, Ryuichi Ohgaki, Kenjiro Tadagaki, Kenji Hamase, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-25870403
  • [Presentation] 腎近位尿細管の第二のシスチントランスポーターの分子同定と機能解析

    • Author(s)
      永森收志、奥山 裕久、Pattama Wiriyasermkul、中込 咲綾、西中 由美子、高藤 和輝、大垣 隆一、金井 好克
    • Organizer
      2012年度 生理研研究会
    • Place of Presentation
      愛知、日本
    • Data Source
      KAKENHI-PROJECT-23790334
  • [Presentation] Evaluation of amino acid transporter LAT1 as a molecular target of anti-tumor therapy by means of the combination of comprehensive proteomics and transport assay.

    • Author(s)
      永森 收志、Pattama Wiriyasermkul、五十棲 規嘉、Pornparn Kongpracha、大垣 隆一、金井 好克
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-25870403
  • [Presentation] 質量分析計と再構成プロテオリポソームを用いた新規トランスポーター複合体の解析-腎尿細管に残された第二のシスチントランスポーターの分子同定

    • Author(s)
      永森收志、奥山 裕久、Pattama Wiriyasermkul、中込 咲綾、西中 由美子、高藤 和輝、大垣 隆一、金井 好克
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡、日本
    • Data Source
      KAKENHI-PROJECT-23790334
  • [Presentation] Evaluation of amino acid transporter LAT1 as a molecular target of anti-tumor therapy by means of the combination of comprehensive proteomics and transport assay. 網羅的プロテオミクスと輸送解析によるアミノ酸トランスポーター LAT1の抗腫瘍薬分子標的としての意義の検討

    • Author(s)
      ○永森 收志、Pattama Wiriyasermkul、五十棲 規嘉、Pornparn Kongpracha、大垣 隆一、金井 好克
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-24390217
  • [Presentation] 表皮バリア形成に必須の 新規リパーゼ様タンパク質mYEH2の役割

    • Author(s)
      大垣隆一
    • Organizer
      花王芸術科学財団 第14回 助成研究発表・交流会
    • Place of Presentation
      東京、日本
    • Data Source
      KAKENHI-PROJECT-23790334
  • [Presentation] 質量分析計と再構成プロテオリポソームを用いた新規トランスポーター複合体の解析-腎尿細管に残された第二のシスチントランスポーターの分子同定

    • Author(s)
      永森收志、奥山 裕久、Pattama Wiriyasermkul、中込 咲綾、西中 由美子、高藤 和輝、大垣 隆一、金井 好克
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡市
    • Data Source
      KAKENHI-PROJECT-24591198
  • [Presentation] 腎近位尿細管の第二のシスチントランスポーターの分子同定と機能解析

    • Author(s)
      永森收志、奥山 裕久、Pattama Wiriyasermkul、中込 咲綾、西中 由美子、高藤 和輝、大垣 隆一、金井 好克
    • Organizer
      生理研研究会『粘膜防御における上皮膜輸送の役割とその破綻による疾病発症メカニズム』
    • Place of Presentation
      岡崎
    • Data Source
      KAKENHI-PROJECT-24591198
  • [Presentation] Transport of 4-borono-L-phenylalanine, a 10B carrier of boron neutron capture therapy, by system L amino acid transporters.

    • Author(s)
      Printip Wongthai, Kohei Hagiwara, Yurika Miyoshi, Pattama Wiriyasermkul, Ryuichi Ohgaki, Kenjiro Tadagaki, Kenji Hamase, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第124回日本薬理学会近畿部会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24659116
  • [Presentation] Evaluation of amino acid transporter LAT1 as a molecular target of anti-tumor therapy by means of the combination of comprehensive proteomics and transport assay.

    • Author(s)
      永森 收志、Pattama Wiriyasermkul、五十棲 規嘉、Pornparn Kongpracha、大垣 隆一、金井 好克
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-24659116
  • [Presentation] 腎尿細管に残された第二のシスチントランスポーターの分子同定

    • Author(s)
      大垣 隆一, 奥山 裕久, Pattama Wiriyasermkul, 中込 咲綾, 西中 由美子, 高藤 和輝, 永森 收志, 金井 好克
    • Organizer
      第3回分子腎臓フォーラム
    • Place of Presentation
      東京、日本
    • Data Source
      KAKENHI-PROJECT-23790334
  • [Presentation] 線虫腸管細胞におけるアミノ酸トランスポーターAAT-6の頂端膜局在に寄与するトランスポートソーム

    • Author(s)
      村田 大輔、○大垣 隆一、萩原 浩平、Kanokporn Phetdee、永森 收志、平田 拓、野村 和子、野村 一也、三谷 昌平、金井 好克
    • Organizer
      第8回トランスポーター研究会年会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-24390217
  • [Presentation] Transport of 4-borono-L-phenylalanine, a 10B carrier of boron neutron capture therapy, by system L amino acid transporters

    • Author(s)
      ○Printip Wongthai, Kohei Hagiwara, Yurika Miyoshi, Pattama Wiriyasermkul, Ryuichi Ohgaki, Kenjiro Tadagaki, Kenji Hamase, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第124回日本薬理学会近畿部会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24390217
  • [Presentation] Mechanisms of tumor cell uptake of 4-borono-phenylalanine, a 10B carrier of boron neutron capture therapy, mediated by system L amino acid transporters.

    • Author(s)
      Printip Wongthai, Kohei Hagiwara, Yurika Miyoshi, Pattama Wiriyasermkul, Pornparn Kongpracha, Isozumi Noriyoshi, Ryuichi Ohgaki, Kenjiro Tadagaki, Kenji Hamase, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-24659116
  • [Presentation] 3-Fluoro-L-α-methyltyrosine (FAMT), a positron emission tomography probe for cancer diagnosis, is a selective substrate of cancer-specific amino acid transporter L-type amino acid transporter 1 (LAT1)

    • Author(s)
      ○Ling Wei、富永 英之、Pattama Wiriyasermkul、大垣 隆一、忠垣 憲次郎、永森 收志、金井 好克
    • Organizer
      第123回日本薬理学会近畿部会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-24390217
  • [Presentation] 線虫アミノ酸トランスポーターAAT-6の輸送機能および細胞内局在の解析.

    • Author(s)
      村田 大輔、大垣 隆一、萩原 浩平、Kanokporn Phetdee、永森 收志、魏 玲、平田 拓、野村 一也、三谷 昌平、金井 好克
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-24659116
  • [Presentation] Kinetic analysis of 3F-L-α-methyltyrosine (FAMT) transport by L-type amino acid transporter 1.

    • Author(s)
      Ling Wei, Hideyuki Tominaka, Pattama Wiriyasermkul, Yumiko Nishinaka, Ryuichi Ohgaki, Kenjiro Tadagaki, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡市
    • Data Source
      KAKENHI-PROJECT-24659116
  • [Presentation] Expression and functional profiles of amino acid transporters in cancer cell lines

    • Author(s)
      ○Pattama Wiriyasermkul, Shushi Nagamori, Noriyoshi Isozumi, Ryuichi Ohgaki, Hideyuki Tominaga and Yoshikatsu Kanai
    • Organizer
      第86回日本生化学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24390217
  • [Presentation] 線虫腸管細胞におけるアミノ酸トランスポーターAAT-6の頂端膜局在に寄与するトランスポートソーム.

    • Author(s)
      村田 大輔、大垣 隆一、萩原 浩平、Kanokporn Phetdee、永森 收志、平田 拓、野村 和子、野村 一也、三谷 昌平、金井 好克
    • Organizer
      第8回トランスポーター研究会年会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-24659116
  • [Presentation] アミノ酸トランスポーターLAT1阻害による血管内皮細胞 チューブ形成への影響についての検討.

    • Author(s)
      原 早織、大垣 隆一、Printip Wongthai、中込 咲綾、永森 收志、金井 好克
    • Organizer
      第124回日本薬理学会近畿部会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-25870403
  • [Presentation] 腎尿細管に残された第二のシスチントランスポーターの分子同定

    • Author(s)
      大垣 隆一, 奥山 裕久, Pattama Wiriyasermkul, 中込 咲綾, 西中 由美子, 高藤 和輝, 永森 收志, 金井 好克
    • Organizer
      第3回分子腎臓フォーラム
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24591198
  • [Presentation] 3-Fluoro-L-a-methyltyrosine (FAMT), a positron emission tomography probe for cancer diagnosis, is a selective substrate of cancer-specific amino acid transporter L-type amino acid transporter 1 (LAT1).

    • Author(s)
      Ling Wei、富永 英之、Pattama Wiriyasermkul、大垣 隆一、忠垣 憲次郎、永森 收志、金井 好克
    • Organizer
      第123回日本薬理学会近畿部会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-25870403
  • [Presentation] 原 早織、大垣 隆一、Printip Wongthai、中込 咲綾、永森 收志、金井 好克:アミノ酸トランスポーターLAT1阻害による血管内皮細胞 チューブ形成への影響についての検討.

    • Author(s)
      原 早織、大垣 隆一、Printip Wongthai、中込 咲綾、永森 收志、金井 好克
    • Organizer
      第124回日本薬理学会近畿部会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24659116
  • [Presentation] アミノ酸トランスポーターLAT1阻害による血管内皮細胞 チューブ形成への影響についての検討

    • Author(s)
      ○原 早織、大垣 隆一、Printip Wongthai、中込 咲綾、永森 收志、金井 好克
    • Organizer
      第124回日本薬理学会近畿部会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24390217
  • [Presentation] Mechanisms of tumor cell uptake of 4-borono-phenylalanine, a 10B carrier of boron neutron capture therapy, mediated by system L amino acid transporters

    • Author(s)
      ○Printip Wongthai, Kohei Hagiwara, Yurika Miyoshi, Pattama Wiriyasermkul, Pornparn Kongpracha, Isozumi Noriyoshi, Ryuichi Ohgaki, Kenjiro Tadagaki, Kenji Hamase, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-24390217
  • [Presentation] 線虫アミノ酸トランスポーターAAT-6の輸送機能および細胞内局在の解析

    • Author(s)
      ○村田 大輔、大垣 隆一、萩原 浩平、Kanokporn Phetdee、永森 收志、魏 玲、平田 拓、野村 一也、三谷 昌平、金井 好克
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-24390217
  • [Presentation] Boronophenylalanine; a rational carrier for 10B for BNCT, is transported by both LAT1 and LAT2.

    • Author(s)
      Printip Wongthai, Pattama Wiriyasermkul, Yumiko Nishinaka, Ryuichi Ohgaki, Kenjiro Tadagaki, Shushi Nagamori, Yoshikatsu Kanai.
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡市
    • Data Source
      KAKENHI-PROJECT-24659116
  • [Presentation] Expression and functional profiles of amino acid transporters in cancer cell lines.

    • Author(s)
      Pattama Wiriyasermkul, Shushi Nagamori, Noriyoshi Isozumi, Ryuichi Ohgaki, Hideyuki Tominaga and Yoshikatsu Kanai
    • Organizer
      第86回日本生化学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-25870403
  • [Presentation] Evaluation of amino acid transporter LAT1 as a molecular target of anti-tumor therapy by means of the combination of comprehensive proteomics and transport assay網羅的プロテオミクスと輸送解析によるアミノ酸トランスポーター LAT1の抗腫瘍薬分子標的としての意義の検討

    • Author(s)
      永森 收志、Pattama Wiriyasermkul、五十棲 規嘉、Pornparn Kongpracha、大垣 隆一、金井 好克
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-24591198
  • [Presentation] 線虫アミノ酸トランスポーターAAT-6の輸送機能および細胞内局在の解析.

    • Author(s)
      村田 大輔、大垣 隆一、萩原 浩平、Kanokporn Phetdee、永森 收志、魏 玲、平田 拓、野村 一也、三谷 昌平、金井 好克
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-25870403
  • [Presentation] Transport of 4-borono-L-phenylalanine, a 10B carrier of boron neutron capture therapy, by system L amino acid transporters.

    • Author(s)
      Printip Wongthai, Kohei Hagiwara, Yurika Miyoshi, Pattama Wiriyasermkul, Ryuichi Ohgaki, Kenjiro Tadagaki, Kenji Hamase, Shushi Nagamori, Yoshikatsu Kanai
    • Organizer
      第124回日本薬理学会近畿部会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-25870403
  • [Presentation] 3-Fluoro-L-a-methyltyrosine (FAMT), a positron emission tomography probe for cancer diagnosis, is a selective substrate of cancer-specific amino acid transporter L-type amino acid transporter 1 (LAT1).

    • Author(s)
      Ling Wei、富永 英之、Pattama Wiriyasermkul、大垣 隆一、忠垣 憲次郎、永森 收志、金井 好克
    • Organizer
      第123回日本薬理学会近畿部会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-24659116
  • 1.  KANAI Yoshikatsu (60204533)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 177 results
  • 2.  NAGAMORI Shushi (90467572)
    # of Collaborated Projects: 12 results
    # of Collaborated Products: 162 results
  • 3.  OKUDA Suguru (50511846)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 112 results
  • 4.  岡西 広樹 (70792589)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 36 results
  • 5.  中込 咲綾 (60423894)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 16 results
  • 6.  徐 旻恵 (20910201)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 22 results
  • 7.  ANZAI Naohiko (70276054)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  HIRATA Taku (60372918)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  NATSUME Tohru (00357683)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  KIMURA Tohru (30433725)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  UENO Takeshi (20406979)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  TANAKA Hidekazu (70273638)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 13.  KANAZAWA Hiroshi (50116448)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  MITSUI Kaiji (60379279)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 15.  MATSUSHITA Masafumi (50403100)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 16.  NISHIZONO Hirofumi (10502289)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  HARI Yoshiyuki (50347423)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  波多野 亮 (60521713)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  ISHIKAWA Junko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  TERAMURA Yuji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  金沢 浩
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 6 results
  • 22.  金 春奐
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 23.  金井 正美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  吉田 竜太郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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