Ohama Tohru 大濱透

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OHAMA Tohru 大濱透

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Researcher Number	20467583
Other IDs
Affiliation (Current)	2025: 関西学院大学, 人間福祉学部, 教授
Affiliation (based on the past Project Information) *help	2024: 大阪大学, 大学院歯学研究科, 助教 2019 – 2021: 大阪大学, 歯学研究科, 助教 2010 – 2012: 大阪大学, 保健センター, 助教 2008 – 2009: 大阪大学, 医学系研究科, 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 52010:General internal medicine-related / Basic Section 59040:Nutrition science and health science-related / Metabolomics Except Principal Investigator Metabolomics
Keywords	Principal Investigator プログラニュリン / 加齢 / 心不全 / 心肥大 / β-catenin / cardiac hypertrophy / atherosclerosis / aging / beta catenin / heart failure … More / cadiac hypertrophy / progranulin / 耐糖能異常 / 痴呆 / 急性冠症候群 / 動脈硬化 / HDL … More Except Principal Investigator ABCG1 / コレステロール逆転送 / 脂質排泄 / ApoA-1 / コレステロール逆転送系 / メタボリックシンドローム / ABCA1 / 粥状動脈硬化 / HDL / アディポネクチン / COUP-TF2 / アポ蛋白B-100 / アポ蛋白A-I / HDLコレステロール / アデイポネクチン Less

老化に伴う循環器疾患におけるProgranulinの役割の解明Principal Investigator
- Principal Investigator
  
  大濱透
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Osaka University
The effect of progranulin on aging-related cardiac hypertrophy and heart failurePrincipal Investigator
- Principal Investigator
  
  Ohama Tohru
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Osaka University
The effect of progranulin, a novel ApoA1-binding protein, on the plaque rapture and the mechanism of dementia onsetPrincipal Investigator
- Principal Investigator
  
  OHAMA Tohru
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Osaka University
Adiponectin prevents atherosclerosis by accelerating reverse cholesterol transport and HDL synthesis
- Principal Investigator
  
  YAMASHITA Shizuya
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Osaka University

All 2020 2011 2010 2009 2008

All Journal Article Presentation

[Journal Article] Progranulin deficiency leads to enhanced age-related cardiac hypertrophy through complement C1q-induced β-catenin activation.2020
- Author(s)
  Zhu Y, Ohama T, Kawase R, Chang J, Inui H, Kanno K, Okada T, Masuda D, Koseki M, Nishida M, Sakata Y, Yamashita S.
- Journal Title
  
  Journal of Molecular and Cellular Cardiology
  
  Volume: 138 Pages: 197-211
- DOI
  10.1016/j.yjmcc.2019.12.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11766, KAKENHI-PROJECT-17H02100, KAKENHI-PROJECT-18H03532, KAKENHI-PROJECT-19K21324
[Journal Article] Adiponectin prevents atherosclerosis by increasing cholesterol efflux from macrophages.2008
- Author(s)
  Tsubakio-Yamamoto K, Matsuura F, Koseki M, Oku H, Sandoval JC, Inagaki M, Nakatani K, Nakaoka H, Kawase R, Yuasa-Kawase M, Masuda D, Ohama T, Maeda N, Nakagawa-Toyama Y, Ishigami M, Nishida M, Kihara S, Shimomura I, Yamashita S
- Journal Title
  
  Biochem Biophys Res Commun 375(3)
  
  Pages: 390-394
- Data Source
  KAKENHI-PROJECT-20390256
[Presentation] A Novel HDL-associated Protein, Progranulin, May Play An Atheroprotective Role By Enhancing Reverse Cholesterol Transport2011
- Author(s)
  大濱透
- Organizer
  第75回日本循環器学会総会・学術集会
- Place of Presentation
  パシフィコ横浜会議センター
- Year and Date
  2011-08-04
- Data Source
  KAKENHI-PROJECT-22591000
[Presentation] Adiponectin might prevent atherosclerosis by COUP-TF2-dependent pathway.2010
- Author(s)
  Yamamoto K, Yamashita S, Ohama T, Masuda D, Sandoval JC, Inagaki M, Nakatani K, Kawase M, Kawase R, Nakaoka H, Toyama Y, Nishida M, Ishigami M, Kihara S, Shimomura I, Komuro I
- Organizer
  第74回日本循環器学会
- Place of Presentation
  京都国際会議場
- Year and Date
  2010-03-07
- Data Source
  KAKENHI-PROJECT-20390256
[Presentation] A Novel HDL-associated Protein, Progranulin, Might Play An Atheroprotective Role By Enhancing Reverse Chelesterol Transport2010
- Author(s)
  大濱透
- Organizer
  ヨーロッパ動脈硬化学会
- Place of Presentation
  Congress Center Hamburg(ドイツ)
- Year and Date
  2010-06-21
- Data Source
  KAKENHI-PROJECT-22591000
[Presentation] Adiponectin enhances de novo hepatic HDL synthesis through LXR alpha-and COUP-TFII-dependent pathways.2010
- Author(s)
  Ohama T, Yamamoto K, Masuda D, Sandoval JC, Inagaki M, Nakatani K, Kawase M, Kawase R, Nakaoka H, Toyama Y, Nishida M, Ishigami M, Kihara S, Shimomura I, Yamashita S, Komuro I
- Organizer
  第74回日本循環器学会
- Place of Presentation
  京都国際会議場
- Year and Date
  2010-03-07
- Data Source
  KAKENHI-PROJECT-20390256
[Presentation] A Novel HDL-associated Protein, Progranulin, May Play An Atheroprotective Role By Enhancing Reverse Cholesterol Transport2010
- Author(s)
  大濱透
- Organizer
  日本動脈硬化学会
- Place of Presentation
  長良川国際会議場(岐阜)
- Year and Date
  2010-07-16
- Data Source
  KAKENHI-PROJECT-22591000
[Presentation] Adiponectin enhances reverse cholesterol transport through de novo hepatic HDL synthesis and apo A-I-mediated cholesterol efflux from macrophages via ABCA1-dependent pathway.2009
- Author(s)
  Yamashita S, Tsubakio-Yamamoto K, Ohama T
- Organizer
  15th International Symposium on Atherosclerosis
- Place of Presentation
  Boston, MA, USA
- Data Source
  KAKENHI-PROJECT-20390256
[Presentation] Role of adiponectin in the atheroprotective system via HDL-cholesterol.2009
- Author(s)
  Ohama T, Yamamoto K, Nakatani K, Inagaki M, Sandoval JC, Masuda D, Toyama Y, Nishida M, Ishigami M, Yamashita S
- Organizer
  15th International Symposium on Atherosclerosis
- Place of Presentation
  Boston, MA, USA
- Data Source
  KAKENHI-PROJECT-20390256
[Presentation] Role of adiponectine in the pathogenesis of dyslipidemia in the metabolic syndrome.2009
- Author(s)
  Ohama T, Yamamoto K, Kawase R, Nakaoka H, Nakatani K, Inagaki M, Sandoval JC, Masuda D, Toyama Y, Nishida M, Ishigami M, Shimomura I, Yamashita S
- Organizer
  第73回日本循環器学会総会・学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2009-03-20
- Data Source
  KAKENHI-PROJECT-20390256
[Presentation] Adiponectin enhances apo-A1-mediated cholesterol efflux from macrophages through ABCA1-dependent pathway.2009
- Author(s)
  Ohama T, Tshibakio-Yamamoto K, Sandoval JC, Inagaki M, Nakatani K, Masuda D, Nakagawa-Toyama Y, Nishida M, Ishigami M, Kihara S, Shimomura I, Yamashita S
- Organizer
  第41回日本動脈硬化学会総会学術集会
- Place of Presentation
  海峡メッセ下関、山口
- Year and Date
  2009-07-18
- Data Source
  KAKENHI-PROJECT-20390256
[Presentation] Role of adiponectin in the atheroprotective system via HDL-Cholesterol2009
- Author(s)
  大濱透
- Organizer
  XV International symposium on Atherosclerosis 2009
- Place of Presentation
  Boston, USA
- Year and Date
  2009-06-15
- Data Source
  KAKENHI-PROJECT-20390256
[Presentation] Adiponectin enhances de novo hepatic HDL synthesis through LXR alpha-and COUP-TFII-dependent pathways.2009
- Author(s)
  Tsubakio-Yamamoto K, Yamashita S, Ohama T, Masuda D, Sandoval JC, Inagaki M, Nakatani K, Yuasa-Kawase M, Kawase R, Nakaoka H, Nakagawa-Toyama Y, Nishida M, Ishigami M, Kihara S, Shimomura I, Komuro I
- Organizer
  82^<nd> American Heart Association Annual Scientific Meeting
- Place of Presentation
  Orlando, FL, USA
- Data Source
  KAKENHI-PROJECT-20390256
[Presentation] Adiponectin deficiency suppresses ABCA1 expression and apoA-I synthesis in the liver.2008
- Author(s)
  Matsuura F, Oku H, Koseki M, Sandoval JC, Yuasa-Kawase M, Tsubakio-Yamamoto K, Masuda D, Maeda N, Ohama T, Ishigami M, Nishida M, Hirano K, Kihara S, Hori M, Shimomura I, Yamashita S
- Organizer
  77th Congress of European Atherosclerosis Society
- Place of Presentation
  Istanbul Lutfi Kindar Convention & Exhibition Centre
- Data Source
  KAKENHI-PROJECT-20390256
[Presentation] Effect of adiponectin on HDL synthesis in the liver.2008
- Author(s)
  Ohama T, Matsuura F, Yamashita S
- Organizer
  第40回日本動脈硬化学会総会・学術集会
- Place of Presentation
  つくば国際会議場
- Year and Date
  2008-07-11
- Data Source
  KAKENHI-PROJECT-20390256

1. YAMASHITA Shizuya (60243242)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results

Ohama Tohru 大濱 透

OHAMA Tohru 大濱 透

Research Projects

Research Products

Co-Researchers

老化に伴う循環器疾患におけるProgranulinの役割の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The effect of progranulin on aging-related cardiac hypertrophy and heart failurePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The effect of progranulin, a novel ApoA1-binding protein, on the plaque rapture and the mechanism of dementia onsetPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Adiponectin prevents atherosclerosis by accelerating reverse cholesterol transport and HDL synthesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Progranulin deficiency leads to enhanced age-related cardiac hypertrophy through complement C1q-induced β-catenin activation.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Adiponectin prevents atherosclerosis by increasing cholesterol efflux from macrophages.2008

Author(s)

Journal Title

Data Source

[Presentation] A Novel HDL-associated Protein, Progranulin, May Play An Atheroprotective Role By Enhancing Reverse Cholesterol Transport2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Adiponectin might prevent atherosclerosis by COUP-TF2-dependent pathway.2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] A Novel HDL-associated Protein, Progranulin, Might Play An Atheroprotective Role By Enhancing Reverse Chelesterol Transport2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Adiponectin enhances de novo hepatic HDL synthesis through LXR alpha-and COUP-TFII-dependent pathways.2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] A Novel HDL-associated Protein, Progranulin, May Play An Atheroprotective Role By Enhancing Reverse Cholesterol Transport2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Adiponectin enhances reverse cholesterol transport through de novo hepatic HDL synthesis and apo A-I-mediated cholesterol efflux from macrophages via ABCA1-dependent pathway.2009

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Role of adiponectin in the atheroprotective system via HDL-cholesterol.2009

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Role of adiponectine in the pathogenesis of dyslipidemia in the metabolic syndrome.2009

Author(s)

Ohama Tohru 大濱透

OHAMA Tohru 大濱透