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Ohama Tohru  大濱 透

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OHAMA Tohru  大濱 透

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Researcher Number 20467583
Other IDs
Affiliation (Current) 2025: 関西学院大学, 人間福祉学部, 教授
Affiliation (based on the past Project Information) *help 2024: 大阪大学, 大学院歯学研究科, 助教
2019 – 2021: 大阪大学, 歯学研究科, 助教
2010 – 2012: 大阪大学, 保健センター, 助教
2008 – 2009: 大阪大学, 医学系研究科, 特任研究員
Review Section/Research Field
Principal Investigator
Basic Section 52010:General internal medicine-related / Basic Section 59040:Nutrition science and health science-related / Metabolomics
Except Principal Investigator
Metabolomics
Keywords
Principal Investigator
プログラニュリン / 加齢 / 心不全 / 心肥大 / β-catenin / cardiac hypertrophy / atherosclerosis / aging / beta catenin / heart failure … More / cadiac hypertrophy / progranulin / 耐糖能異常 / 痴呆 / 急性冠症候群 / 動脈硬化 / HDL … More
Except Principal Investigator
ABCG1 / コレステロール逆転送 / 脂質排泄 / ApoA-1 / コレステロール逆転送系 / メタボリックシンドローム / ABCA1 / 粥状動脈硬化 / HDL / アディポネクチン / COUP-TF2 / アポ蛋白B-100 / アポ蛋白A-I / HDLコレステロール / アデイポネクチン Less
  • Research Projects

    (4 results)
  • Research Products

    (15 results)
  • Co-Researchers

    (1 People)
  •  老化に伴う循環器疾患におけるProgranulinの役割の解明Principal Investigator

    • Principal Investigator
      大濱 透
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Osaka University
  •  The effect of progranulin on aging-related cardiac hypertrophy and heart failurePrincipal Investigator

    • Principal Investigator
      Ohama Tohru
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Osaka University
  •  The effect of progranulin, a novel ApoA1-binding protein, on the plaque rapture and the mechanism of dementia onsetPrincipal Investigator

    • Principal Investigator
      OHAMA Tohru
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Osaka University
  •  Adiponectin prevents atherosclerosis by accelerating reverse cholesterol transport and HDL synthesis

    • Principal Investigator
      YAMASHITA Shizuya
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      Osaka University

All 2020 2011 2010 2009 2008

All Journal Article Presentation

  • [Journal Article] Progranulin deficiency leads to enhanced age-related cardiac hypertrophy through complement C1q-induced β-catenin activation.2020

    • Author(s)
      Zhu Y, Ohama T, Kawase R, Chang J, Inui H, Kanno K, Okada T, Masuda D, Koseki M, Nishida M, Sakata Y, Yamashita S.
    • Journal Title

      Journal of Molecular and Cellular Cardiology

      Volume: 138 Pages: 197-211

    • DOI

      10.1016/j.yjmcc.2019.12.009

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K11766, KAKENHI-PROJECT-17H02100, KAKENHI-PROJECT-18H03532, KAKENHI-PROJECT-19K21324
  • [Journal Article] Adiponectin prevents atherosclerosis by increasing cholesterol efflux from macrophages.2008

    • Author(s)
      Tsubakio-Yamamoto K, Matsuura F, Koseki M, Oku H, Sandoval JC, Inagaki M, Nakatani K, Nakaoka H, Kawase R, Yuasa-Kawase M, Masuda D, Ohama T, Maeda N, Nakagawa-Toyama Y, Ishigami M, Nishida M, Kihara S, Shimomura I, Yamashita S
    • Journal Title

      Biochem Biophys Res Commun 375(3)

      Pages: 390-394

    • Data Source
      KAKENHI-PROJECT-20390256
  • [Presentation] A Novel HDL-associated Protein, Progranulin, May Play An Atheroprotective Role By Enhancing Reverse Cholesterol Transport2011

    • Author(s)
      大濱透
    • Organizer
      第75回日本循環器学会総会・学術集会
    • Place of Presentation
      パシフィコ横浜会議センター
    • Year and Date
      2011-08-04
    • Data Source
      KAKENHI-PROJECT-22591000
  • [Presentation] Adiponectin might prevent atherosclerosis by COUP-TF2-dependent pathway.2010

    • Author(s)
      Yamamoto K, Yamashita S, Ohama T, Masuda D, Sandoval JC, Inagaki M, Nakatani K, Kawase M, Kawase R, Nakaoka H, Toyama Y, Nishida M, Ishigami M, Kihara S, Shimomura I, Komuro I
    • Organizer
      第74回日本循環器学会
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2010-03-07
    • Data Source
      KAKENHI-PROJECT-20390256
  • [Presentation] A Novel HDL-associated Protein, Progranulin, Might Play An Atheroprotective Role By Enhancing Reverse Chelesterol Transport2010

    • Author(s)
      大濱透
    • Organizer
      ヨーロッパ動脈硬化学会
    • Place of Presentation
      Congress Center Hamburg(ドイツ)
    • Year and Date
      2010-06-21
    • Data Source
      KAKENHI-PROJECT-22591000
  • [Presentation] Adiponectin enhances de novo hepatic HDL synthesis through LXR alpha-and COUP-TFII-dependent pathways.2010

    • Author(s)
      Ohama T, Yamamoto K, Masuda D, Sandoval JC, Inagaki M, Nakatani K, Kawase M, Kawase R, Nakaoka H, Toyama Y, Nishida M, Ishigami M, Kihara S, Shimomura I, Yamashita S, Komuro I
    • Organizer
      第74回日本循環器学会
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2010-03-07
    • Data Source
      KAKENHI-PROJECT-20390256
  • [Presentation] A Novel HDL-associated Protein, Progranulin, May Play An Atheroprotective Role By Enhancing Reverse Cholesterol Transport2010

    • Author(s)
      大濱透
    • Organizer
      日本動脈硬化学会
    • Place of Presentation
      長良川国際会議場(岐阜)
    • Year and Date
      2010-07-16
    • Data Source
      KAKENHI-PROJECT-22591000
  • [Presentation] Adiponectin enhances reverse cholesterol transport through de novo hepatic HDL synthesis and apo A-I-mediated cholesterol efflux from macrophages via ABCA1-dependent pathway.2009

    • Author(s)
      Yamashita S, Tsubakio-Yamamoto K, Ohama T
    • Organizer
      15th International Symposium on Atherosclerosis
    • Place of Presentation
      Boston, MA, USA
    • Data Source
      KAKENHI-PROJECT-20390256
  • [Presentation] Role of adiponectin in the atheroprotective system via HDL-cholesterol.2009

    • Author(s)
      Ohama T, Yamamoto K, Nakatani K, Inagaki M, Sandoval JC, Masuda D, Toyama Y, Nishida M, Ishigami M, Yamashita S
    • Organizer
      15th International Symposium on Atherosclerosis
    • Place of Presentation
      Boston, MA, USA
    • Data Source
      KAKENHI-PROJECT-20390256
  • [Presentation] Role of adiponectine in the pathogenesis of dyslipidemia in the metabolic syndrome.2009

    • Author(s)
      Ohama T, Yamamoto K, Kawase R, Nakaoka H, Nakatani K, Inagaki M, Sandoval JC, Masuda D, Toyama Y, Nishida M, Ishigami M, Shimomura I, Yamashita S
    • Organizer
      第73回日本循環器学会総会・学術集会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2009-03-20
    • Data Source
      KAKENHI-PROJECT-20390256
  • [Presentation] Adiponectin enhances apo-A1-mediated cholesterol efflux from macrophages through ABCA1-dependent pathway.2009

    • Author(s)
      Ohama T, Tshibakio-Yamamoto K, Sandoval JC, Inagaki M, Nakatani K, Masuda D, Nakagawa-Toyama Y, Nishida M, Ishigami M, Kihara S, Shimomura I, Yamashita S
    • Organizer
      第41回日本動脈硬化学会総会学術集会
    • Place of Presentation
      海峡メッセ下関、山口
    • Year and Date
      2009-07-18
    • Data Source
      KAKENHI-PROJECT-20390256
  • [Presentation] Role of adiponectin in the atheroprotective system via HDL-Cholesterol2009

    • Author(s)
      大濱透
    • Organizer
      XV International symposium on Atherosclerosis 2009
    • Place of Presentation
      Boston, USA
    • Year and Date
      2009-06-15
    • Data Source
      KAKENHI-PROJECT-20390256
  • [Presentation] Adiponectin enhances de novo hepatic HDL synthesis through LXR alpha-and COUP-TFII-dependent pathways.2009

    • Author(s)
      Tsubakio-Yamamoto K, Yamashita S, Ohama T, Masuda D, Sandoval JC, Inagaki M, Nakatani K, Yuasa-Kawase M, Kawase R, Nakaoka H, Nakagawa-Toyama Y, Nishida M, Ishigami M, Kihara S, Shimomura I, Komuro I
    • Organizer
      82^<nd> American Heart Association Annual Scientific Meeting
    • Place of Presentation
      Orlando, FL, USA
    • Data Source
      KAKENHI-PROJECT-20390256
  • [Presentation] Adiponectin deficiency suppresses ABCA1 expression and apoA-I synthesis in the liver.2008

    • Author(s)
      Matsuura F, Oku H, Koseki M, Sandoval JC, Yuasa-Kawase M, Tsubakio-Yamamoto K, Masuda D, Maeda N, Ohama T, Ishigami M, Nishida M, Hirano K, Kihara S, Hori M, Shimomura I, Yamashita S
    • Organizer
      77th Congress of European Atherosclerosis Society
    • Place of Presentation
      Istanbul Lutfi Kindar Convention & Exhibition Centre
    • Data Source
      KAKENHI-PROJECT-20390256
  • [Presentation] Effect of adiponectin on HDL synthesis in the liver.2008

    • Author(s)
      Ohama T, Matsuura F, Yamashita S
    • Organizer
      第40回日本動脈硬化学会総会・学術集会
    • Place of Presentation
      つくば国際会議場
    • Year and Date
      2008-07-11
    • Data Source
      KAKENHI-PROJECT-20390256
  • 1.  YAMASHITA Shizuya (60243242)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results

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