Tanegashima Kosuke 種子島幸祐

… Alternative Names

TANEGASHIMA Kosuke 種子島幸祐

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Researcher Number	20507678
Other IDs	https://orcid.org/0000-0001-8733-8538
Affiliation (Current)	2025: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, 主席研究員 2025: 公益財団法人東京都医学総合研究所, 先端基礎医科学研究分野, 主席研究員
Affiliation (based on the past Project Information) *help	2020 – 2024: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, 主席研究員 2018 – 2019: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 主席研究員 2012 – 2015: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 主任研究員 2011: 財団法人東京都医学総合研究所, 生体分子先端研究分野, 研究員 2010: (財)東京都医学総合研究所, 東京都臨床医学総合研究所, 主任研究員 2009: Tokyo Metropolitan Organization for Medical Research, 東京都臨床医学総合研究所, 主任研究員 2008 – 2009: Tokyo Metropolitan Organization for Medical Research, 東京都臨床医学総合研究所, 主任研究員
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Embryonic/Neonatal medicine / Experimental pathology / Biological Sciences
Keywords	Principal Investigator CXCL14 / CpG DNA / Tumor immunity / 腫瘍免疫 / tumor immunity / ケモカイン / CXCR4 / 相同組み替え / ES細胞 / シグナル伝達 … More / WGEF / ノックアウトマウス / 脳・神経 / 発生・分化 / 神経管閉鎖障害 / 先天異常学 / Innate immune response / CpG ODN / Innate Immunity / DAMPs / TLR9 / innate immunity / CXCL12 / 炎症反応 / 炎症 / ストレス応答 / 摂食行動 Less

自然免疫活性化核酸受容体の小胞輸送による腫瘍免疫調節機構Principal Investigator
- Principal Investigator
  
  種子島幸祐
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Molecular Mechanisms of Nucleic Acid Receptors in Activating Innate Immune Respnses and Tumor Immunity.Principal Investigator
- Principal Investigator
  
  TANEGASHIMA Kosuke
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Mecanisms of cooperation between CXCL14 and DNA for activation of innate immune responces and tumor immunityPrincipal Investigator
- Principal Investigator
  
  TANEGASHIMA Kosuke
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Regulation of macrophage in adipose tissue by CXCL14 and its receptor.Principal Investigator
- Principal Investigator
  
  TANEGASHIMA Kosuke
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
新奇ストレス環境における摂食抑制とケモカインシグナルPrincipal Investigator
- Principal Investigator
  
  種子島幸祐
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Regulation of morphogenetic movements by a guanine nucleotide-exchange factor involved in Wnt-PCP pathwayPrincipal Investigator
- Principal Investigator
  
  TANEGASHIMA Kosuke
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  公益財団法人東京都医学総合研究所
   Tokyo Metropolitan Organization for Medical Research
Genetic analysis of a guanine nucleotide exchanging factor involved in neural tube morphogenesisPrincipal Investigator
- Principal Investigator
  
  TANEGASHIMA Kosuke
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Tokyo Metropolitan Organization for Medical Research

[Book] 臨床免疫・アレルギー科　第57巻　増刊号　サイトカインのすべて2012
- Author(s)
  種子島　幸祐, 原　孝彦
- Total Pages
  5
- Publisher
  科学評論社
- Data Source
  KAKENHI-PUBLICLY-23126528
[Book] 臨床免疫・アレルギー科　第57巻　増刊号　サイトカインのすべて2012
- Author(s)
  種子島　幸祐, 原　孝彦
- Total Pages
  5
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-22791043
[Book] 臨床免疫・アレルギー科第57巻増刊号サイトカインのすべて「CXCL14」
- Author(s)
  種子島幸祐, 原孝彦
- Data Source
  KAKENHI-PROJECT-22791043
[Journal Article] Identification of Low-Density Lipoprotein Receptor-Related Protein 1 as a CXCL14 Receptor Using Chemically Synthesized Tetrafunctional Probes2024
- Author(s)
  Miyajima Rin、Tanegashima Kosuke、Naruse Naoto、Denda Masaya、Hara Takahiko、Otaka Akira
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 19 Issue: 2 Pages: 551-562
- DOI
  10.1021/acschembio.3c00717
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07208, KAKENHI-PROJECT-22K15253
[Journal Article] Identification of compounds that preferentially suppress the growth of T‐cell acute lymphoblastic leukemia‐derived cells2023
- Author(s)
  Miyashita Kazuya, Yagi Takuya, Kagaya Noritaka, Takechi Azusa, Nakata Chihiro, Kanda Risa, Nuriya Hideko, Tanegashima Kosuke, et al.
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 10 Pages: 4032-4040
- DOI
  10.1111/cas.15918
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07208
[Journal Article] Circadian protection against bacterial skin infection by epidermal CXCL14-mediated innate immunity2022
- Author(s)
  Tsujihana Kojiro、Tanegashima Kosuke、Santo Yasuko、Yamada Hiroyuki、Akazawa Sota、Nakao Ryuta、Tominaga Keiko、Saito Risa、Nishito Yasumasa、Hata Ryu-Ichiro、Nakamura Tomonori、Murai Iori、Kono Yuka、Sugawa Maho、Tanioka Miki、Egawa Gyohei、Doi Masao、Isa Tadashi、Kabashima Kenji、Hara Takahiko、Okamura Hitoshi
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 119 Issue: 25 Pages: 25-25
- DOI
  10.1073/pnas.2116027119
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07208, KAKENHI-PROJECT-22K18384, KAKENHI-PROJECT-20K20864, KAKENHI-ORGANIZER-20H05760, KAKENHI-ORGANIZER-20H05782, KAKENHI-PLANNED-20H05783, KAKENHI-PROJECT-22H04987, KAKENHI-PROJECT-20K08702, KAKENHI-PROJECT-20K21426, KAKENHI-PROJECT-18H04015, KAKENHI-PROJECT-20H05697, KAKENHI-PROJECT-22H04992, KAKENHI-PROJECT-22H00441
[Journal Article] 新型コロナウイルス擬似ウイルスを用いた感染性評価系の開発2021
- Author(s)
  種子島　幸祐, 原　孝彦
- Journal Title
  
  第１７回東京都福祉保健医療学会抄録
  
  Volume: 17 Pages: 46-47
- Data Source
  KAKENHI-PROJECT-21K07208
[Journal Article] Identification of functional domains of CXCL14 involved in high-affinity binding and intracellular transport of CpG DNA2021
- Author(s)
  R. Iwase, N. Naruse, M. Nakagawa, R. Saito, A. Shigenaga, A. Otaka, T. Hara, and K. Tanegashima
- Journal Title
  
  J. Immunol.
  
  Volume: 207 Issue: 2 Pages: 459-469
- DOI
  10.4049/jimmunol.2100030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08702, KAKENHI-PROJECT-21K07208
[Journal Article] Latrophilin2 is involved in neural crest cell migration and placode patterning in Xenopus laevis.2019
- Author(s)
  Yokote N., Suzuki-Kosaka Y. M., Michiue T., Hara T., Tanegashima K.
- Journal Title
  
  International Journal of Developmental Biology
  
  Volume: 63 Issue: 1-2 Pages: 29-35
- DOI
  10.1387/ijdb.180184kt
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07313, KAKENHI-PROJECT-16H04728, KAKENHI-PROJECT-17KT0049, KAKENHI-PROJECT-18K06244, KAKENHI-PUBLICLY-18H04967, KAKENHI-PUBLICLY-19H04948
[Journal Article] LIM homeobox transcription factor Lhx2 inhibits skeletal muscle differentiation in part via transcriptional activation of Msx1 and Msx22015
- Author(s)
  Kodaka Y, Tanaka K, Kitajima K, Tanegashima K, Matsuda R, Hara T.
- Journal Title
  
  Exp Cell Res.
  
  Volume: 331 Pages: 309-319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860304
[Journal Article] Efficient one-pot synthesis of CXCL14 and its derivative using an N-sulfanylethylanilide peptide as a peptide thioester equivalent and their biological evaluation2015
- Author(s)
  Kohei Tsuji, Kosuke Tanegashima, Kohei Sato, Ken Sakamoto, Akira Shigenaga, Tsubasa Inokuma, Takahiko Hara and Akira Otaka
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 23 Issue: 17 Pages: 5909-5914
- DOI
  10.1016/j.bmc.2015.06.064
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K14979, KAKENHI-PROJECT-25860304
[Journal Article] 『ケモカインと幹細胞』　CXCL12-CXCR4 軸を介した幹細胞誘引の調節因子2014
- Author(s)
  原　孝彦, 種子島　幸祐
- Journal Title
  
  日本薬理学雑誌
  
  Volume: 144 Pages: 4-7
- NAID
  130004437204
- Data Source
  KAKENHI-PROJECT-25860304
[Journal Article] CXCL14 antagonizes the CXCL12-CXCR4 signaling axis2014
- Author(s)
  Hara T, Tanegashima K.
- Journal Title
  
  Biomol Concepts.
  
  Volume: 5 Issue: 2 Pages: 167-173
- DOI
  10.1515/bmc-2014-0007
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25860304
[Journal Article] CXCL14 is a natural inhibitor of the CXCL12-CXCR4 signaling axis2013
- Author(s)
  Tanegashima K, Suzuki K, Nakayama Y, Tsuji K, Shigenaga, A, Otaka A, Hara T
- Journal Title
  
  FEBS Lett
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791043
[Journal Article] Dimeric peptides of the C-terminal region of CXCL14 function as CXCL12 inhibitors2013
- Author(s)
  K. Tanegashima, K. Tsuji, K. Su zuki, A. Shigenaga, A. Otaka, and T. Hara
- Journal Title
  
  FEBS Letters
  
  Volume: 587 Issue: 23 Pages: 3770-3775
- DOI
  10.1016/j.febslet.2013.10.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J08863, KAKENHI-PROJECT-23390256, KAKENHI-PROJECT-25860304
[Journal Article] CXCL14 is a natural inhibitor of the CXCL12-CXCR4 signaling axis2013
- Author(s)
  K. Tanegashima, K. Suzukia, Y. Nakayama, K. Tsuji, A. Shigenaga, A. Otaka, and T. tiara
- Journal Title
  
  FEBS Letters
  
  Volume: 587 Issue: 12 Pages: 1731-1735
- DOI
  10.1016/j.febslet.2013.04.046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J08863, KAKENHI-PROJECT-22791043, KAKENHI-PROJECT-23390256, KAKENHI-PROJECT-23659055, KAKENHI-PROJECT-23659481, KAKENHI-PROJECT-25860304, KAKENHI-PUBLICLY-23126528
[Journal Article] Pleiotropic functions of the CXC-type chemokine CXCL14 in mammals2012
- Author(s)
  Hara T, Tanegashima K
- Journal Title
  
  J.Biochem.
  
  Volume: 151 Pages: 469-476
- NAID
  10031166086
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23126528
[Journal Article] Pleiotropic functions of the CXC-type chemokine CXCL14 in mammals2012
- Author(s)
  Hara T, Tanegashima K
- Journal Title
  
  J.Biochem.
  
  Volume: 151 Pages: 469-476
- NAID
  10031166086
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791043
[Journal Article] Pleiotropic functions of the CXC-type chemokine CXCL14 in mammals2012
- Author(s)
  Hara T, Tanegashima K
- Journal Title
  
  J. Biochem
  
  Volume: 151 Pages: 469-476
- NAID
  10031166086
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791043
[Journal Article] XIer2 is required for convergent extension movements during Xenopus development2011
- Author(s)
  Hong SK, Tanegashima K, Dawid IB
- Journal Title
  
  Int.J.Dev.Biol.
  
  Volume: 55 Pages: 917-921
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791043
[Journal Article] Application of N-C-or C-N-directed sequential native chemical ligation to the preparation of CXCL14 analogs and their biological evaluation2011
- Author(s)
  Tsuji K, Shigenaga A, Sumikawa Y, Tanegashima K, Sato K, Aihara K, Hara T, Otaka A
- Journal Title
  
  Bioorg.Med.Chem.
  
  Volume: 19 Pages: 4014-4020
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23126528
[Journal Article] XIer2 is required for convergent extension movements during Xenopus development2011
- Author(s)
  Hong SK, Tanegashima K, Dawid IB
- Journal Title
  
  Int.J.Dev.Biol.
  
  Volume: 55 Pages: 917-921
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23126528
[Journal Article] Application of N-C- or C-N-directed sequential native chemical ligation to the preparation of CXCL14 analogs and their biological evaluation2011
- Author(s)
  Tsuji K, Shigenaga A, Sumikawa Y, Tanegashima K, Sato K, Aihara K, Hara T, Otaka A
- Journal Title
  
  Bioorg.Med.Chem.
  
  Volume: 19 Pages: 4014-4020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791043
[Journal Article] XIer2 is required for convergent extension movements during Xenopus development2011
- Author(s)
  Hong SK, Tanegashima K, Dawid IB
- Journal Title
  
  Int. J. Dev. Biol
  
  Volume: 55 Pages: 917-921
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791043
[Journal Article] Application of N-C- or C-N-directed sequential native chemical ligation to the preparation of CXCL14 analogs and their biological evaluation2011
- Author(s)
  Tsuji K, Shigenaga A, Sumikawa Y, Tanegashima K, Sato K, Aihara K, Hara T, Otaka A
- Journal Title
  
  Bioorg. Med. Chem
  
  Volume: 19 Pages: 4014-4020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791043
[Journal Article] CXCL14 deficiency in mice attenuates obesity and inhibits feeding behavior in a novel environment.2010
- Author(s)
  Tanegashima K, Okamoto S, Nakayama Y, Taya C, Shitara H, Ishii R, Yonekawa H, Minokoshi Y, Hara T.
- Journal Title
  
  PLoS One
  
  Volume: 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791043
[Journal Article] Antibody-assisted enhancement of biological activities of CXCL14 in human monocytic leukemia-derived THP-1 cells and high fat diet-induced obese mice2010
- Author(s)
  Tanegashima K, Suzuki K, Nakayama Y, Hara T.
- Journal Title
  
  Exp. Cell. Res. 316
  
  Pages: 1263-1270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890292
[Journal Article] CXCL14 deficiency in mice attenuates obesity and inhibits feeding behavior in a novel environment2010
- Author(s)
  Tanegashima K, Okamoto S, Nakayama Y, Taya C, Shitara H, Ishii R, Yonekawa H, Minokoshi Y, Hara T
- Journal Title
  
  PLoS One
  
  Volume: 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791043
[Journal Article] Antibody-assisted enhancement of biological activities of CXCL14 in human monocytic leukemia-derived THP-1 cells and high fat diet-induced obese mice2010
- Author(s)
  Tanegashima K, Suzuki K, Nakayama Y, Hara T.
- Journal Title
  
  Experimental Cell Research 316
  
  Pages: 1263-1270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890292
[Journal Article] Coordinated activation of the secretory pathway during notochord formation in the Xenopus embryo2009
- Author(s)
  Tanegashima K, Zhao H, Rebbert ML, Dawid IB.
- Journal Title
  
  Development. 136
  
  Pages: 3543-3548
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890292
[Journal Article] XLRIG3 regulates neural crest formation by mediating FGF and Wnt signaling pathways2008
- Author(s)
  Zhao, H, Tanegashima, K, Dawid, IB
- Journal Title
  
  Development 135
  
  Pages: 1283-1293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890292
[Patent] CXCR4活性阻害ペプチド及びその用途2011
- Inventor(s)
  原孝彦、種子島幸祐、大高章、重永章
- Industrial Property Rights Holder
  財団法人東京都医学総合研究所、国立大学法人徳島大学
- Industrial Property Number
  2011-251758
- Filing Date
  2011-11-17
- Data Source
  KAKENHI-PROJECT-22791043
[Patent] CXCR4活性阻害ペプチド及びその用途2011
- Inventor(s)
  原孝彦、種子島幸祐、大高章、重永章
- Industrial Property Rights Holder
  財団法人東京都医学総合研究所、国立大学法人徳島大学
- Industrial Property Number
  2011-251758
- Filing Date
  2011-11-17
- Data Source
  KAKENHI-PUBLICLY-23126528
[Presentation] Circadian protection against bacterial over-proliferation in the skin by the CXCL14/bacterial DNA/TLR9 pathway2024
- Author(s)
  種子島幸祐、辻花　光次郎、椛島　健治、岡村　均、原孝彦
- Organizer
  第101回日本生理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K07208
[Presentation] Fine tuning of TLR9 signaling triggered by CpG DNA-CXCL14 complex is mediated by Immunoglobulin superfamily proteins and scavenger receptors.2024
- Author(s)
  種子島幸祐、斎藤理佐、髙橋　陸、長谷部　愛佳、原孝彦
- Organizer
  第52回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07208
[Presentation] ケモカインCXCL14とIg superfamily タンパクによる二重鎖DNAの細胞内送達2023
- Author(s)
  髙橋　陸、種子島　幸祐、斎藤　理佐、原　孝彦
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07208
[Presentation] SARS-CoV-2の脂質ラフトを介した細胞侵入機構の解明2022
- Author(s)
  小松谷啓介、菊池紀仁、小倉潔、川島育夫、酒井祥太、深澤征義、花田賢太郎、長田直樹、種子島幸祐、原孝彦、笠原浩二
- Organizer
  第15回セラミド研究会
- Data Source
  KAKENHI-PROJECT-21K07208
[Presentation] SARS-CoV-2 の脂質ラフトを介した細胞内取り込み2022
- Author(s)
  小松谷啓介、菊池紀仁、小倉潔、川島育夫、花田賢太郎、長田直樹、種子島幸祐、原孝彦、笠原浩二
- Organizer
  第95回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-21K07208
[Presentation] ケモカインCXCL14とIg superfamily タンパクによるオリゴデオキシヌクレオチドの細胞内送達機構の解析2022
- Author(s)
  種子島幸祐、斎藤理佐、原孝彦
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07208
[Presentation] Innate immune responses triggered by CpG DNA-CXCL14 complex is mediated by Immunogloblin superfamily proteins2022
- Author(s)
  斎藤理佐、種子島幸祐、原孝彦
- Organizer
  第51回日本免疫学会年会
- Data Source
  KAKENHI-PROJECT-21K07208
[Presentation] 新型コロナウイルス擬似ウイルスを用いた感染性評価系の開発2021
- Author(s)
  種子島　幸祐、原孝彦
- Organizer
  第17回東京都福祉保健医療学会
- Data Source
  KAKENHI-PROJECT-21K07208
[Presentation] SARS-CoV-2のガングリオシドラフトを介した細胞内取り込み2021
- Author(s)
  小松谷啓介、小倉潔、菊池紀仁、川島育夫、花田賢太郎、長田直樹、種子島幸祐、原孝彦、笠原浩二
- Organizer
  第40回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-21K07208
[Presentation] Ig superfamily膜タンパク質はCpG DNA/CXCL14複合体に結合する2021
- Author(s)
  斎藤　理佐, 種子島　幸祐, 成瀬公人, 重永章, 大髙章, 原　孝彦
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07208
[Presentation] CXCケモカインのCpG ODN細胞内送達活性の分子メカニズム2020
- Author(s)
  種子島幸祐, 岩瀬璃奈, 中川美帆, 斎藤理佐, 成瀬公人, 重永章, 大髙章, 原孝彦
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K07313
[Presentation] CpG DNAとCXCL14による自然免疫系の協調的な調節メカニズム2019
- Author(s)
  種子島幸祐, 三井貴洋, 岩瀬　璃奈, 成瀬公人, 重永章, 大髙章, 原孝彦
- Organizer
  第38回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K07313
[Presentation] CXCL14 delivers CpG DNA, and enhances TLR9 signaling in dendritic cells and macrophages2019
- Author(s)
  種子島幸祐, 三井貴洋, 成瀬公人, 辻耕平, 重永章, 大髙章, 原孝彦
- Organizer
  第19回遺伝子デリバリー研究会シンポジウム
- Data Source
  KAKENHI-PROJECT-18K07313
[Presentation] ケモカインCXCL14の脳内ミクログリアに対する働き2019
- Author(s)
  中川美帆, 種子島幸祐, 三井貴洋, 成瀬公人, 重永章, 大髙章, 佐久間啓, 原孝彦
- Organizer
  第38回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K07313
[Presentation] ケモカインSDF-1αによるJurkat T細胞移動の脂質ラフトを介するシグナル伝達2019
- Author(s)
  福山美智子、井口智弘、小松谷啓介、川島育夫、下仲基之、種子島幸祐、原孝彦、山本正雅、笠原浩二
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K07313
[Presentation] CXCL14とCpG DNAの相互作用によるTLR9活性化の特異性と責任領域の解析2018
- Author(s)
  岩瀬璃奈, 成瀬公人, 種子島幸祐 , 重永章, 大髙章, 原孝彦
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K07313
[Presentation] CpG DNA/CXCL14複合体に対する候補受容体の発現クローニング2018
- Author(s)
  三井貴洋, 種子島幸祐, 成瀬公人, 重永章, 大髙章, 原孝彦
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K07313
[Presentation] ケモカインCXCL14は癌細胞のヘパラン硫酸に高親和性で結合する.2015
- Author(s)
  髙橋伶奈, 種子島幸祐, 辻　耕平, 重永　章, 大髙　章, 原　孝彦.
- Organizer
  第38回日本分子生物学会年会,
- Place of Presentation
  神戸ポートピアホテル(兵庫県神戸市)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25860304
[Presentation] β-ヒドロキシ酪酸によるHDACの阻害はGlut1の発現上昇を介して脳グルコース恒常性に寄与する.2015
- Author(s)
  種子島幸祐, 佐藤由紀子, 西藤　泰昌, 相垣　敏郎, 原　孝彦.
- Organizer
  第38回日本分子生物学会年会,
- Place of Presentation
  神戸ポートピアホテル(兵庫県神戸市)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25860304
[Presentation] Functional interaction between Latrophilin-2 and Teneurin-2/4 in the migration of neural crest cells.2015
- Author(s)
  Tanegashima K., Yokote N., Suzuki M. Y., Michiue T., Hara T.
- Organizer
  第48回日本発生生物学会年会,
- Place of Presentation
  筑波国際会議場　（茨城県つくば市）
- Year and Date
  2015-06-02
- Data Source
  KAKENHI-PROJECT-25860304
[Presentation] Gタンパク質共役型レセプターLatrophilin-2はプラコードと神経堤細胞の相互作用に関与する.2015
- Author(s)
  横手夏美, 種子島幸祐, 鈴木マリアンナ由乃, 道上達男, 原　孝彦.
- Organizer
  第38回日本分子生物学会年会,
- Place of Presentation
  神戸ポートピアホテル(兵庫県神戸市)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25860304
[Presentation] 新奇ストレス環境における摂食抑制とケモカインシグナル2012
- Author(s)
  種子島幸祐
- Organizer
  新学術領域第三回班会議 (食欲と脂肪蓄積の制御と破綻の分子基盤の解明)
- Place of Presentation
  千里サイエンスセンター
- Data Source
  KAKENHI-PROJECT-22791043
[Presentation] 新奇ストレス環境における摂食抑制とケモカインシグナル2012
- Author(s)
  種子島幸祐
- Organizer
  新学術領域第三回班会議
- Place of Presentation
  千里サイエンスセンター
- Data Source
  KAKENHI-PROJECT-22791043
[Presentation] ケモカインCXCL14とその受容体を介した脂肪蓄積制御2012
- Author(s)
  種子島幸祐, 鈴木健司, 原孝彦
- Organizer
  第33回日本肥満学会
- Place of Presentation
  ホテルグランビア京都
- Data Source
  KAKENHI-PROJECT-22791043
[Presentation] ケモカインCXCL14とその受容体を介した脂肪蓄積制御2012
- Author(s)
  種子島幸祐, 鈴木　健司, 原孝彦
- Organizer
  第33回日本肥満学会
- Place of Presentation
  ホテルグランビア京都
- Year and Date
  2012-10-11
- Data Source
  KAKENHI-PUBLICLY-23126528
[Presentation] 新奇ストレス環境における摂食抑制とケモカインシグナル2012
- Author(s)
  種子島幸祐
- Organizer
  新学術領域第三回班会議
- Place of Presentation
  千里サイエンスセンター
- Year and Date
  2012-08-23
- Data Source
  KAKENHI-PUBLICLY-23126528
[Presentation] CXCR4 and Latrophillin-2 are required for CXCL14-mediated chemotaxis2011
- Author(s)
  鈴木健司, 種子島幸祐, 中山由紀, 重永章, 大高章, 長澤丘司, 森正明, 原孝彦
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PUBLICLY-23126528
[Presentation] 新奇ストレス環境における摂食抑制とケモカインシグナル2011
- Author(s)
  種子島幸祐
- Organizer
  新学術領域第二回班会議,食欲と脂肪蓄積の制御と破綻の分子基盤の解明
- Place of Presentation
  大阪府豊中市
- Year and Date
  2011-08-19
- Data Source
  KAKENHI-PROJECT-22791043
[Presentation] CXCR4 and Latrophillin-2 are required for CXCL14-mediated chemotaxis2011
- Author(s)
  鈴木健司, 種子島幸祐, 中山由紀, 重永章, 大高章,長澤丘司, 森正明, 原孝彦
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22791043
[Presentation] CXCR4 and Latrophillin-2 are required for CXCL14-mediated chemotaxis2011
- Author(s)
  鈴木健司, 種子島幸祐, 中山由紀, 重永章, 大高章, 長澤丘司, 森正明, 原孝彦
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22791043
[Presentation] ケモカインCXCL14を介した摂食調節機構の解析2011
- Author(s)
  種子島幸祐, 岡本士毅, 中山由紀, 多屋長治, 設楽浩志, 石井里絵, 米川博通, 箕越靖彦, 原孝彦
- Organizer
  第32回日本肥満学会
- Place of Presentation
  兵庫県淡路市
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PUBLICLY-23126528
[Presentation] ケモカインCXCL14を介した摂食調節機構の解析2011
- Author(s)
  種子島幸祐, 岡本士毅, 中山由紀, 多屋長治, 設楽浩志, 石井里絵, 米川博通, 箕越靖彦, 原孝彦
- Organizer
  第32回日本肥満学会
- Place of Presentation
  兵庫県淡路市
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-22791043
[Presentation] 新奇ストレス環境における摂食抑制とケモカインシグナル2011
- Author(s)
  種子島幸祐
- Organizer
  新学術領域第二回班会議 (食欲と脂肪蓄積の制御と破綻の分子基盤の解明)
- Place of Presentation
  千里サイエンスセンター
- Year and Date
  2011-08-19
- Data Source
  KAKENHI-PROJECT-22791043
[Presentation] 新奇ストレス環境における摂食抑制とケモカインシグナル2011
- Author(s)
  種子島幸祐
- Organizer
  新学術領域第二回班会議,食欲と脂肪蓄積の制御と破綻の分子基盤の解明
- Place of Presentation
  大阪府豊中市
- Year and Date
  2011-08-19
- Data Source
  KAKENHI-PUBLICLY-23126528
[Presentation] ケモカインCXCL14 を介した摂食調節機構の解析2011
- Author(s)
  種子島幸祐, 岡本士毅, 中山由紀, 多屋長治, 設楽浩志, 石井里絵, 米川博通, 箕越靖彦, 原孝彦
- Organizer
  第32回日本肥満学会
- Place of Presentation
  兵庫県淡路市
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-22791043
[Presentation] ケモカインCXCL14を介した摂食調節2010
- Author(s)
  種子島幸祐, 岡本士毅, 中山由紀, 多屋長治, 設楽浩志, 石井里絵, 米川博通, 箕越靖彦, 原孝彦
- Organizer
  第二十四回モロシヌス研究会
- Place of Presentation
  ホテルグリーンピア南阿蘇、熊本県南阿蘇
- Data Source
  KAKENHI-PROJECT-22791043
[Presentation] CXCL14 is required for body weight gain in female mice Keystone symposia2009
- Author(s)
  Hara T, Nakayama Y, Tanegashima K
- Organizer
  Obesity: Novel Aspects of the Regulation of Body Weight
- Place of Presentation
  Faremont Spring Hotel, Canada
- Data Source
  KAKENHI-PROJECT-20890292
[Presentation] CXCL14 deficiency attenuates obesity and inhibits feeding behavior in a novel environment2009
- Author(s)
  種子島幸祐, 岡本士毅, 中山由紀, 多屋長治, 設楽浩志, 石井里絵, 米川博通, 箕越靖彦, 原孝彦
- Organizer
  第32回日本分子生物学会
- Place of Presentation
  神奈川県・パシフィコ横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-20890292
[Presentation] CXCL14 is required for body weight gain in female mice2009
- Author(s)
  Hara T, Nakayama Y, Tanegashima K
- Organizer
  Keystone symposia, Obesity : Novel Aspects of the Regulation of Body Weight
- Place of Presentation
  Faremont Spring Hotel
- Data Source
  KAKENHI-PROJECT-20890292
[Presentation] Antibody-assisted enhancement of chemotactic activity of CXCL14 in human monocytic leukemia-derived THP-1 cells2009
- Author(s)
  鈴木健司, 種子島幸祐, 中山由紀, 原孝彦
- Organizer
  第32回日本分子生物学会
- Place of Presentation
  神奈川県・パシフィコ横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-20890292
[Presentation] Antibody-assisted enhancement of chemotactic activity of CXCL14 in human monocytic leukemia-derived THP-1 cells2009
- Author(s)
  鈴木健司, 種子島幸祐, 中山由紀, 原孝彦
- Organizer
  第三十二回日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-20890292
[Presentation] CXCL14 deficiency attenuates obesity and inhibits feeding behavior in a novel environment2009
- Author(s)
  種子島幸祐, 岡本士毅, 中山由紀, 多屋長治, 設楽浩志, 石井里絵, 米川博通, 箕越靖彦, 原孝彦
- Organizer
  第三十二回日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-20890292
[Presentation] Notochord differentiation requires activation of the Unfolded Protein Response2008
- Author(s)
  Kosuke Tanegashima, Hui Zhao, Martha Rebbert, Igor Dawid
- Organizer
  12th international Xenopus conference
- Place of Presentation
  Leiwen/Trier, Germany
- Year and Date
  2008-09-12
- Data Source
  KAKENHI-PROJECT-20890292
[Presentation] ケモカインCXCL14の生理的役割とシグナル伝達経路の解析2008
- Author(s)
  種子島幸祐、鈴木健司、原孝彦
- Organizer
  第三十一回日本分子生物学会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20890292
[Presentation] Latrophilin-2 is involved in the migration and differentiation of neural crest cells.
- Author(s)
  Tanegashima K., Suzuki M. Y., Suzuki K., Michiue T., Hara T.
- Organizer
  第47回日本発生生物学会年会,
- Place of Presentation
  ウインク愛知　(愛知県名古屋市)
- Year and Date
  2014-05-28 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-25860304
[Presentation] One-pot chemical synthesis of CXCL14 using N-sulfanylethylanilide peptide
- Author(s)
  Tsuji K., Sato K., Sakamoto, K., Tanegashima K., Shigenaga A., Inokuma T., Hara T., Otaka A.
- Organizer
  第51回ペプチド討論会
- Place of Presentation
  徳島大学大塚講堂　（徳島県徳島市）
- Year and Date
  2014-10-22 – 2014-10-24
- Data Source
  KAKENHI-PROJECT-25860304
[Presentation] オーファンGタンパク質共役型レセプターLatrophilin-2の神経堤細胞遊走への関与
- Author(s)
  鈴木　マリアンナ由乃,種子島　幸祐, 鈴木　健司, 道上　達男, 原　孝彦
- Organizer
  第三十六回分子生物学会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-25860304
[Presentation] Identification of The CXCL14 Receptor: CXCL14 is a Natural Inhibitor of The CXCL12/CXCR4 Axis.
- Author(s)
  種子島幸祐, 鈴木　健司, 長澤　丘司, 原孝彦
- Organizer
  第十一回幹細胞シンポジウム
- Place of Presentation
  東京大学伊藤国際学術研究センター
- Data Source
  KAKENHI-PROJECT-25860304
[Presentation] Modulation of CXCR4-mediated signaling pathway by CXCL14.
- Author(s)
  Tanegashima K., Ohta S., K. Suzuki, K. Tsuji, A. Shigenaga, A. Otaka, T. Hara.
- Organizer
  CBSM International Joint Symposium
- Place of Presentation
  Andong, Korea.
- Year and Date
  2014-06-20 – 2014-06-21
- Data Source
  KAKENHI-PROJECT-25860304
[Presentation] ケモカインCXCL14は、CXCL12-CXCR4シグナル経路を阻害する
- Author(s)
  種子島　幸祐
- Organizer
  第三十六回分子生物学会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-25860304

1. 大高章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 原孝彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tanegashima Kosuke 種子島 幸祐

TANEGASHIMA Kosuke 種子島 幸祐

Research Projects

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Co-Researchers

自然免疫活性化核酸受容体の小胞輸送による腫瘍免疫調節機構Principal Investigator

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Molecular Mechanisms of Nucleic Acid Receptors in Activating Innate Immune Respnses and Tumor Immunity.Principal Investigator

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Mecanisms of cooperation between CXCL14 and DNA for activation of innate immune responces and tumor immunityPrincipal Investigator

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Regulation of macrophage in adipose tissue by CXCL14 and its receptor.Principal Investigator

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新奇ストレス環境における摂食抑制とケモカインシグナルPrincipal Investigator

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Regulation of morphogenetic movements by a guanine nucleotide-exchange factor involved in Wnt-PCP pathwayPrincipal Investigator

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Genetic analysis of a guanine nucleotide exchanging factor involved in neural tube morphogenesisPrincipal Investigator

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[Book] 臨床免疫・アレルギー科 第57巻 増刊号 サイトカインのすべて2012

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[Book] 臨床免疫・アレルギー科 第57巻 増刊号 サイトカインのすべて2012

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[Book] 臨床免疫・アレルギー科 第57巻 増刊号 サイトカインのすべて 「CXCL14」

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[Journal Article] Identification of Low-Density Lipoprotein Receptor-Related Protein 1 as a CXCL14 Receptor Using Chemically Synthesized Tetrafunctional Probes2024

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[Journal Article] Identification of compounds that preferentially suppress the growth of T‐cell acute lymphoblastic leukemia‐derived cells2023

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[Journal Article] Circadian protection against bacterial skin infection by epidermal CXCL14-mediated innate immunity2022

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[Journal Article] 新型コロナウイルス擬似ウイルスを用いた感染性評価系の開発2021

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[Journal Article] Identification of functional domains of CXCL14 involved in high-affinity binding and intracellular transport of CpG DNA2021

Tanegashima Kosuke 種子島幸祐

TANEGASHIMA Kosuke 種子島幸祐

[Book] 臨床免疫・アレルギー科　第57巻　増刊号　サイトカインのすべて2012

[Book] 臨床免疫・アレルギー科　第57巻　増刊号　サイトカインのすべて2012

[Book] 臨床免疫・アレルギー科第57巻増刊号サイトカインのすべて「CXCL14」

[Journal Article] 『ケモカインと幹細胞』　CXCL12-CXCR4 軸を介した幹細胞誘引の調節因子2014