NAGAI TOSHIHIRO 長井敏洋

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NAGAI Toshihiro 長井敏洋

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Researcher Number	20514376
Other IDs
Affiliation (Current)	2025: 東海大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2016 – 2018: 東海大学, 医学部, 講師 2013 – 2014: 東海大学, 医学部, 講師 2009 – 2010: Tokai University, 医学部, 助教
Review Section/Research Field	Principal Investigator Orthopaedic surgery
Keywords	Principal Investigator 関節軟骨修復 / 変形性関節症 / mutipleチロシンキナーゼ受容体阻害剤 / multiple チロシンキナーゼ受容体阻害剤 / 変形性関節症修復剤 / multipleチロシンキナーゼ受容体阻害剤 / 血管新生阻害剤 / bevacizumab (avastin) / 抗ＶＥＧＦ抗体 / avastin … More / bevacizumab / ベバシズマブ（アバスチン） / 抗VEGF抗体 / chondromodulin-I / allograft / tissue enginggred carti / scaffold free / 組織工学的軟骨 / 同種移植 / 組織工学軟骨 / 軟骨修復 Less

Research Projects
(3 results)
Research Products
(27 results)

Inhibitory effect of the multiple receptor tyrosine kinase inhibitor on osteoarthritisPrincipal Investigator
- Principal Investigator
  
  NAGAI Toshihiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Tokai University
Potential of the arthritis joint treatment with antiVEGF antibody intraarticular administrationPrincipal Investigator
- Principal Investigator
  
  NAGAI Toshihiro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Tokai University
Repair of articular cartilage with scaffold-free chondrocyte platesPrincipal Investigator
- Principal Investigator
  
  NAGAI Toshihiro
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Tokai University

All 2018 2017 2015 2014 2013 2011 2010 2009 Other

All Journal Article Presentation Book

[Book] Tissue Engineering2010
- Author(s)
  K.Furukawa, T.Nagai, et al
- Total Pages
  20
- Publisher
  Scaffold-free Cartilage Tissue by Mechanical Stress for Tissue Engineering
- Data Source
  KAKENHI-PROJECT-21791420
[Book] Scaffold-free Cartilage Tissue by Mechanical Stress Loading for Tissue Engineering.
- Author(s)
  K.Furukawa, M.Sato, T.Nagai, S.Ting, J.Mochida, T.Ushida
- Publisher
  In Tech Tissue Engineering
- Data Source
  KAKENHI-PROJECT-21791420
[Journal Article] 片側椎間関節脱臼を伴った外傷性軸椎すべりtypeⅢの２例2015
- Author(s)
  額賀唯至渡辺雅彦長井敏洋檜山明彦酒井大輔佐藤正人持田讓治
- Journal Title
  
  関東整形災害外科学会雑誌
  
  Volume: 46 Pages: 17-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861345
[Journal Article] Bevacizumab, an anti-vascular endothelial growth factor antibody, inhibits osteoarthritis2014
- Author(s)
  Toshihiro Nagai, Masato Sato, Miyuki Yokoyama, Munetaka Yokoyama, Yoshiki Tani, Joji Mochida
- Journal Title
  
  Arthritis Research and Therapy
  
  Volume: 16 Issue: 5 Pages: 427-427
- DOI
  10.1186/s13075-014-0427-y
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25861345
[Journal Article] Intravenous administration of anti-vascular endothelial growth factor humanized monoclonal antibody bevacizumab improves articular cartilage repair2010
- Author(s)
  T.Nagai, et al
- Journal Title
  
  Arthritia Research & Therapy
  
  Volume: 12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791420
[Journal Article] Noninvasive evaluation of tissue engineered cartilage with time resolved laser induced fluorescence spectroscopy2010
- Author(s)
  T.Kustuna, M.Sato, M.Ishihara, K.Furukawa, T.Nagai, T.Ushida, S.Kikuchi, J.Mochida
- Journal Title
  
  Tissue Engineering Part C Methods 16(3)
  
  Pages: 365-373
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791420
[Journal Article] Noninvasive evaluation of tissue engineered cartilage with time -resolved laser-induced fluorescence spectroscopy2009
- Author(s)
  Kutsuna T, Nagai T, et al.
- Journal Title
  
  Tissue Engineering Part C
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791420
[Presentation] Inhibitory effect of lenvatinib, a multiple receptor tyrosine kinase inhibitor, on osteoarthritis2018
- Author(s)
  Yasuyuki　Sogo, Toshihiro Nagai, Takumi Takahashi, Daichi Takizawa, Masahiko Watanabe, Masato Sato
- Organizer
  The 2018 Osteoarthritis Research Society International (OARSI) World Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10919
[Presentation] 多標的チロシンキナーゼ受容体阻害薬Lenvatinibによる変形性関節症抑制効果2018
- Author(s)
  十河泰之長井敏洋佐藤正人高橋匠滝澤大智岡田恵理前原美樹豊田恵利子
- Organizer
  第33回日本整形外科学会基礎学術総会
- Data Source
  KAKENHI-PROJECT-16K10919
[Presentation] The effect of cage geometry on segmental lordosis in posterior lumbar interbody fusion: hyper-lordotic box cages versus boomerang cages2018
- Author(s)
  Toshihiro Nagai, Daisuke Sakai, Yukihiro Yamamoto, Masato Sato, Masahiko Watanabe
- Organizer
  45th ISSLS Annual Meeting - Banff, Canada, 14th - 18th May 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10919
[Presentation] 12°wedge cage・boomerang cage・box cageによる後方進入椎体間固定術後の局所前弯角の検討2018
- Author(s)
  長井敏洋新井文征佐藤正人渡辺雅彦
- Organizer
  第67回　東日本整形災害外科学会
- Data Source
  KAKENHI-PROJECT-16K10919
[Presentation] 後方進入椎体間固定術の下位腰椎椎間における前弯獲得について：使用ケージの形状の差による比較検討2018
- Author(s)
  長井敏洋酒井大輔新井文征佐藤正人渡辺雅彦
- Organizer
  第27回　日本脊椎インストゥルメンテーション学会
- Data Source
  KAKENHI-PROJECT-16K10919
[Presentation] VEGF受容体チロシンキナーゼ阻害剤 Lenvatinibによる滑膜炎抑制効果2017
- Author(s)
  十河泰之　長井敏洋　佐藤正人　高橋匠　滝澤大智　岡田恵里　前原美樹　豊田恵利子　渡辺雅彦
- Organizer
  第32回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-16K10919
[Presentation] Prevention of post-traumatic osteoarthritis by administration of2014
- Author(s)
  Toshihiro Nagai
- Organizer
  ORS 60th annual meeting
- Place of Presentation
  New Orleans LA
- Data Source
  KAKENHI-PROJECT-25861345
[Presentation] ウサギ膝前十字靭帯切離モデルを用いた抗VEGF抗体ヒト化モノクローナル抗体（bevacizumab）の関節内投与による軟骨変性抑制効果の検討2013
- Author(s)
  長井　敏洋
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  千葉幕張メッセ国際会議場
- Data Source
  KAKENHI-PROJECT-25861345
[Presentation] 血管新生阻害剤(Bevacizumab)静脈内投与による関節軟骨修復の検討2011
- Author(s)
  長井敏洋、佐藤正人、沓名寿治、太田直司、海老原吾郎、持田讓治
- Organizer
  第10回日本再生医療学会
- Place of Presentation
  東京
- Year and Date
  2011-03-01
- Data Source
  KAKENHI-PROJECT-21791420
[Presentation] Repair of articular cartilage with anti-VEGF antibody bevacizumab2011
- Author(s)
  T.Nagai, M.Sato, T.Kutsuna, S.Ito, M.Kokubo, J.Mochida
- Organizer
  2011 Annual Meeting of the Orthopaedic Research Society
- Place of Presentation
  Long Beach, Califolnia
- Data Source
  KAKENHI-PROJECT-21791420
[Presentation] 抗VEGFヒト化モノクローナル抗体(Bevacizumab)による軟骨修復効果2010
- Author(s)
  長井敏洋、佐藤正人、沓名寿治、太田直司、海老原吾郎、小久保舞美、持田讓治
- Organizer
  第25回日本整形外科基礎学術集会
- Place of Presentation
  京都
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-21791420
[Presentation] Intravenous administration of Bevacizumab may contribute to better repair of articular cartilage.2010
- Author(s)
  T.Nagai, M.Sato, T.Kutsuna, G.Ebihara, J.Mochida
- Organizer
  56^<th> Orthopaedic Research Society
- Place of Presentation
  New Orleans, Louisiana
- Data Source
  KAKENHI-PROJECT-21791420
[Presentation] Intravenous administration of Bevacizumab may contribute to better repair of articular cartilage2010
- Author(s)
  T.Nagai, et al.
- Organizer
  56th Annual Meeting of the Orthopedic Research Society
- Place of Presentation
  New Orleans
- Data Source
  KAKENHI-PROJECT-21791420
[Presentation] 抗VEGFヒト化モノクローナル抗体(Bevacizumab)による関節軟骨修復効果2010
- Author(s)
  長井敏洋、佐藤正人、沓名寿治、海老原吾郎、太田直司、持田讓治
- Organizer
  第9回日本再生医療学会
- Place of Presentation
  広島
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-21791420
[Presentation] 血管新生阻害効果による関節軟骨修復の検討2010
- Author(s)
  長井敏洋
- Organizer
  第29回日本運動器移植・再生医学研究会
- Place of Presentation
  京都
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-21791420
[Presentation] 治血管新生阻害効果による関節軟骨修復の検討2010
- Author(s)
  長井敏洋、佐藤正人、古川克子、沓名寿治、海老原吾郎、太田直司、伊藤聡、小久保舞美、鵜養拓、牛田多加志、持田讓
- Organizer
  第29回日本運動器移植・再生医学研究会
- Place of Presentation
  京都
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-21791420
[Presentation] 抗VEGFヒト化モノクローナル抗体(Bevacizumab)による軟骨修復効果2009
- Author(s)
  長井敏洋、沓名寿治、太田直司、海老原吾郎、持田讓治
- Organizer
  第24回日本整形外科学会基礎学術集会
- Place of Presentation
  神奈川
- Year and Date
  2009-11-06
- Data Source
  KAKENHI-PROJECT-21791420
[Presentation] Repair of articular cartilage with scaffold-free chondrocyte plates2009
- Author(s)
  T.Nagai, et al.
- Organizer
  8th world congress of the international cartilage repairo society
- Place of Presentation
  Miami
- Data Source
  KAKENHI-PROJECT-21791420
[Presentation] Repair of articular cartilage with scaffold-free chondrocyte plates.2009
- Author(s)
  T.Nagai, M.Sato, Furukawa.S.K, Ushida.T, J.Mochida
- Organizer
  8^<th> world congress of the international cartilage repair society
- Place of Presentation
  Miami, Florida
- Data Source
  KAKENHI-PROJECT-21791420
[Presentation] 強直性脊椎障害患者の転位ある頚椎骨折に対する前方プレートの問題点
- Author(s)
  長井敏洋渡辺雅彦佐藤正人東永廉酒井大輔加藤裕幸檜山明彦持田讓治
- Organizer
  第23回日本脊椎インストゥルメンテーション学会
- Place of Presentation
  アクトシティ浜松
- Year and Date
  2014-08-29 – 2014-08-30
- Data Source
  KAKENHI-PROJECT-25861345

NAGAI TOSHIHIRO 長井 敏洋

NAGAI Toshihiro 長井 敏洋

Research Projects

Research Products

Inhibitory effect of the multiple receptor tyrosine kinase inhibitor on osteoarthritisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Potential of the arthritis joint treatment with antiVEGF antibody intraarticular administrationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Repair of articular cartilage with scaffold-free chondrocyte platesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Tissue Engineering2010

Author(s)

Total Pages

Publisher

Data Source

[Book] Scaffold-free Cartilage Tissue by Mechanical Stress Loading for Tissue Engineering.

Author(s)

Publisher

Data Source

[Journal Article] 片側椎間関節脱臼を伴った外傷性軸椎すべりtypeⅢの２例2015

Author(s)

Journal Title

Data Source

[Journal Article] Bevacizumab, an anti-vascular endothelial growth factor antibody, inhibits osteoarthritis2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intravenous administration of anti-vascular endothelial growth factor humanized monoclonal antibody bevacizumab improves articular cartilage repair2010

Author(s)

Journal Title

Data Source

[Journal Article] Noninvasive evaluation of tissue engineered cartilage with time resolved laser induced fluorescence spectroscopy2010

Author(s)

Journal Title

Data Source

[Journal Article] Noninvasive evaluation of tissue engineered cartilage with time -resolved laser-induced fluorescence spectroscopy2009

Author(s)

Journal Title

Data Source

[Presentation] Inhibitory effect of lenvatinib, a multiple receptor tyrosine kinase inhibitor, on osteoarthritis2018

Author(s)

Organizer

Data Source

[Presentation] 多標的チロシンキナーゼ受容体阻害薬Lenvatinibによる変形性関節症抑制効果2018

Author(s)

Organizer

Data Source

[Presentation] The effect of cage geometry on segmental lordosis in posterior lumbar interbody fusion: hyper-lordotic box cages versus boomerang cages2018

Author(s)

Organizer

Data Source

[Presentation] 12°wedge cage・boomerang cage・box cageによる後方進入椎体間固定術後の局所前弯角の検討2018

Author(s)

Organizer

Data Source

[Presentation] 後方進入椎体間固定術の下位腰椎椎間における前弯獲得について：使用ケージの形状の差による比較検討2018

Author(s)

Organizer

Data Source

[Presentation] VEGF受容体チロシンキナーゼ阻害剤 Lenvatinibによる滑膜炎抑制効果2017

Author(s)

Organizer

Data Source

[Presentation] Prevention of post-traumatic osteoarthritis by administration of2014

Author(s)

Organizer

Place of Presentation

NAGAI TOSHIHIRO 長井敏洋

NAGAI Toshihiro 長井敏洋