Takata takanobu 高田尊信

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TAKATA Takanobu 高田尊信

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Researcher Number	20515308
Other IDs
Affiliation (Current)	2025: 金沢医科大学, 総合医学研究所, 講師
Affiliation (based on the past Project Information) *help	2018 – 2024: 金沢医科大学, 総合医学研究所, 講師 2013 – 2016: 金沢医科大学, 総合医学研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Eating habits Except Principal Investigator Eating habits
Keywords	Principal Investigator 生活習慣病 / 終末糖化産物 / LC3 / オートファジー / 心臓線維芽細胞 / 心筋細胞 / 心疾患 / 毒性終末糖化産物 / TAGE / 漢方製剤 … More / 口腔粘膜上皮細胞 / 甘味飲食品 / 口腔粘膜障害 / p62 / LC-3 / 膵島β細胞 / GFP / 子宮頸癌細胞 / Heat shock protein 90 / 2アミノ酸残基結合型 / 1アミノ酸残基結合型 / 質量分析 / Multiple AGE pattern / Diverse AGE pattern / Crude AGE pattern / 甘味飲料 / 初代培養心筋細胞 / 心血管疾患 / 果糖ブドウ糖液糖 / 肝実質細胞 / 細胞生存率 / 高濃度フルクトース / 高濃度グルコース / 肝臓 / 骨格筋筋芽細胞 / TAGE化蛋白質 / 細胞死 / 拍動低下 / 細胞外TAGE / 血中TAGE / 細胞内TAGE / 拍動 / 糖尿病 / 食習慣 / 膵癌 … More Except Principal Investigator NASH / 食習慣 / 終末糖化産物 / 電子顕微鏡 / オートファジー / 小胞体ストレス / 初代培養肝細胞 / 初代培養心筋細胞 / グリセルアルデヒド / 終末糖化タンパク / 食生活 / 生活習慣病 / TAGE / NAFLD Less

The mechanisms of oral epithelial dysfunction based on advanced glycation end-products and screening of Kampo medicines for prevention and treatmentPrincipal Investigator
- Principal Investigator
  
  高田尊信
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kanazawa Medical University
Mechanisms of cytotoxicity due to the generation and accumulation of toxic advanced glycation end-prodcuts (TAGE) in cardiomyocytesPrincipal Investigator
- Principal Investigator
  
  高田尊信
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kanazawa Medical University
Elucidating the cardiomyocytes damage caused by Toxic Advanced Glycation End-products (TAGE) and the underlying mechanismPrincipal Investigator
- Principal Investigator
  
  TAKATA Takanobu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kanazawa Medical University
Excessive ingestion of sugar causes the abnomality of endoplasmic reticulum, resulting in providing for NASH
- Principal Investigator
  
  UEDA Tadashi
- Project Period (FY)
  2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Eating habits
- Research Institution
  Kanazawa Medical University
Identification of the promoter proteins for pancreatic cancer which concurred with diabetes and research of effect of the compounds in citrus fruits which investigation is approached from AGEs.Principal Investigator
- Principal Investigator
  
  TAKATA Takanobu
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Eating habits
- Research Institution
  Kanazawa Medical University
Association between characteristics of current diet and onset/deterioration of non-alcoholic fatty liver disease
- Principal Investigator
  
  TAKEUCHI Masayoshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Eating habits
- Research Institution
  Kanazawa Medical University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014

All Journal Article Presentation Book

[Book] アンチエイジングのための100の質問2014
- Author(s)
  高田尊信、竹内正義
- Total Pages
  2
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-25282029
[Journal Article] Analysis of Crude, Diverse, and Multiple Advanced Glycation End-Product Patterns May Be Important and Beneficial2024
- Author(s)
  Takanobu Takata, Togen Masauji, Yoshiharu Motoo
- Journal Title
  
  Metabolites
  
  Volume: 14 Issue: 1 Pages: 3-3
- DOI
  10.3390/metabo14010003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11607
[Journal Article] Novel In Vitro Assay of the Effects of Kampo Medicines against Intra/Extracellular Advanced Glycation End-Products in Oral, Esophageal, and Gastric Epithelial Cells2023
- Author(s)
  Takanobu Takata, Yoshiharu Motoo
- Journal Title
  
  Metabolites
  
  Volume: 13 Issue: 7 Pages: 878-878
- DOI
  10.3390/metabo13070878
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11607
[Journal Article] Is the Novel Slot Blot a Useful Method for Quantification of Intracellular Advanced Glycation End-Products?2023
- Author(s)
  Takanobu Takata
- Journal Title
  
  Metabolites
  
  Volume: 13 Issue: 4 Pages: 564-564
- DOI
  10.3390/metabo13040564
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11607
[Journal Article] Potential of the Novel Slot Blot Method with a PVDF Membrane for Protein Identification and Quantification in Kampo Medicines2023
- Author(s)
  Takanobu Takata, Togen Masauji, Yoshiharu Motoo
- Journal Title
  
  Membranes (Basel)
  
  Volume: 13 Issue: 12 Pages: 896-896
- DOI
  10.3390/membranes13120896
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11607
[Journal Article] Intracellular Toxic Advanced Glycation End-Products May Induce Cell Death and Suppress Cardiac Fibroblasts2022
- Author(s)
  Takata Takanobu、Sakasai-Sakai Akiko、Takeuchi Masayoshi
- Journal Title
  
  Metabolites
  
  Volume: 12 Issue: 7 Pages: 615-615
- DOI
  10.3390/metabo12070615
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11583, KAKENHI-PROJECT-21K11607, KAKENHI-PROJECT-21H04865
[Journal Article] Intracellular Toxic Advanced Glycation End-Products in 1.4E7 Cell Line Induce Death with Reduction of Microtubule-Associated Protein 1 Light Chain 3 and p622022
- Author(s)
  Takata Takanobu、Sakasai-Sakai Akiko、Takeuchi Masayoshi
- Journal Title
  
  Nutrients
  
  Volume: 14 Issue: 2 Pages: 332-332
- DOI
  10.3390/nu14020332
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04865, KAKENHI-PROJECT-21K11583, KAKENHI-PROJECT-21K11607
[Journal Article] Effects of Toxic AGEs (TAGE) on Human Health2022
- Author(s)
  Takeuchi Masayoshi、Sakasai-Sakai Akiko、Takata Takanobu、Takino Jun-ichi、Koriyama Yoshiki
- Journal Title
  
  Cells
  
  Volume: 11 Issue: 14 Pages: 2178-2178
- DOI
  10.3390/cells11142178
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K11583, KAKENHI-PROJECT-21K11607, KAKENHI-PROJECT-22K09844, KAKENHI-PROJECT-21H04865
[Journal Article] The Association between Accumulation of Toxic Advanced Glycation End-Products and Cytotoxic Effect in MC3T3-E1 Cells2022
- Author(s)
  Sakasai-Sakai Akiko、Takata Takanobu、Takeuchi Masayoshi
- Journal Title
  
  Nutrients
  
  Volume: 14 Issue: 5 Pages: 990-990
- DOI
  10.3390/nu14050990
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04865, KAKENHI-PROJECT-21K11607
[Journal Article] Accumulation of Toxic Advanced Glycation End-Products Induces Cytotoxicity and Inflammation in Hepatocyte-Like Cells Differentiated from Human Induced Pluripotent Stem Cells2021
- Author(s)
  Kikuchi Chigusa、Sakasai-Sakai Akiko、Okimura Risa、Tanaka Hinako、Takata Takanobu、Takeuchi Masayoshi、Matsunaga Tamihide
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 44 Issue: 10 Pages: 1399-1402
- DOI
  10.1248/bpb.b21-00520
- NAID
  130008095843
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2021-10-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04865, KAKENHI-PROJECT-21K11583, KAKENHI-PROJECT-21K11607
[Journal Article] Potential of an Interorgan Network Mediated by Toxic Advanced Glycation End-Products in a Rat Model2021
- Author(s)
  Shinya Inoue, Takanobu Takata, Yusuke Nakazawa, Yuka Nakamura, Xin Guo, Sohsuke Yamada, Yasuhito Ishigaki, Masayoshi Takeuchi, Katsuhito Miyazawa
- Journal Title
  
  Nutrients
  
  Volume: 13 Issue: 1 Pages: 80-80
- DOI
  10.3390/nu13010080
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11139, KAKENHI-PROJECT-18K16714
[Journal Article] Comprehensive analysis of protein-expression changes specific to immunoglobulin G4-related disease2021
- Author(s)
  Kawanami Takafumi、Kawanami-Iwao Haruka、Takata Takanobu、Ishigaki Yasuhito、Tomosugi Naohisa、Takegami Tsutomu、Yanagisawa Hiroto、Fujimoto Shino、Sakai Tomoyuki、Fujita Yoshimasa、Yamada Kazunori、Mizuta Shuichi、Kawabata Hiroshi、Fukushima Toshihiro、Hirose Yuko、Masaki Yasufumi
- Journal Title
  
  Clinica Chimica Acta
  
  Volume: 523 Pages: 45-57
- DOI
  10.1016/j.cca.2021.08.025
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04865, KAKENHI-PROJECT-17K09999, KAKENHI-PROJECT-21K08449, KAKENHI-PROJECT-21K08483, KAKENHI-PROJECT-21K11607
[Journal Article] Intracellular Toxic AGEs (TAGE) Triggers Numerous Types of Cell Damage.2021
- Author(s)
  Takeuchi M, Sakasai-Sakai A, Takata T, Takino JI, Koriyama Y, Kikuchi C, Furukawa A, Nagamine K, Hori T, Matsunaga T.
- Journal Title
  
  Biomolecules.
  
  Volume: 11 Issue: 3 Pages: 387-387
- DOI
  10.3390/biom11030387
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11781, KAKENHI-PROJECT-20K20320, KAKENHI-PROJECT-18K11003, KAKENHI-PROJECT-18K11139, KAKENHI-PROJECT-21H04865, KAKENHI-PROJECT-21K11583
[Journal Article] Intracellular Toxic Advanced Glycation End-Products Promote the Production of Reactive Oxygen Species in HepG2 Cells2020
- Author(s)
  Sakasai-Sakai Akiko、Takata Takanobu、Takeuchi Masayoshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 14 Pages: 4861-4861
- DOI
  10.3390/ijms21144861
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11003, KAKENHI-PROJECT-18K11139
[Journal Article] Impact of intracellular toxic advanced glycation end-products (TAGE) on murine myoblast cell death2020
- Author(s)
  Takata Takanobu、Sakasai-Sakai Akiko、Takeuchi Masayoshi
- Journal Title
  
  Diabetology & Metabolic Syndrome
  
  Volume: 12 Issue: 1 Pages: 54-54
- DOI
  10.1186/s13098-020-00561-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11003, KAKENHI-PROJECT-18K11139
[Journal Article] 第3のグリコーゲン代謝物1,5-アンヒドロ-D-フルクトース（1,5-AF）の謎を探る2020
- Author(s)
  逆井（坂井）亜紀子, 高田尊信, 鈴木宏一, 丸山征郎, 田中賢治, 本宮善恢, 竹内正義
- Journal Title
  
  日本未病学会雑誌
  
  Volume: 26 Pages: 67-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K11139
[Journal Article] The relevance of toxic AGEs (TAGE) cytotoxicity to NASH pathogenesis: A Mini-Review2019
- Author(s)
  Akiko Sakasai-Sakai, Takanobu Takata, Jun-ichi Takino, Masayoshi Takeuchi
- Journal Title
  
  Nutrients
  
  Volume: 11 Pages: 462-462
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11139
[Journal Article] Evidence for Toxic Advanced Glycation End-Products Generated in the Normal Rat Liver2019
- Author(s)
  Takanobu Takata, Akiko Sakasai-Sakai, Jun-ichi Takino, Masayoshi Takeuchi
- Journal Title
  
  Nutrients
  
  Volume: 11 Pages: 1612-1612
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11139
[Journal Article] Intracellular toxic advanced glycation end-products in cardiomyocytes may cause cardiovascular disease2019
- Author(s)
  Takata Takanobu、Sakasai-Sakai Akiko、Ueda Tadashi、Takeuchi Masayoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 2121-2121
- DOI
  10.1038/s41598-019-39202-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11003, KAKENHI-PROJECT-18K11139, KAKENHI-PROJECT-16H01811
[Journal Article] Immunological evidence for in vivo production of novel advanced glycation end-products from 1,5-anhydro-D-fructose, a glycogen metabolite2019
- Author(s)
  Sakasai-Sakai Akiko、Takata Takanobu、Suzuki Hirokazu、Maruyama Ikuro、Motomiya Yoshihiro、Takeuchi Masayoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 10194-10194
- DOI
  10.1038/s41598-019-46333-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11003, KAKENHI-PROJECT-18K11139, KAKENHI-PROJECT-16H01811, KAKENHI-PROJECT-16K10746, KAKENHI-PROJECT-18K19587
[Journal Article] Serum levels of toxic AGEs (TAGE) may be a promising novel biomarker in development and progression of NASH.2015
- Author(s)
  Takeuchi M, Sakasai-Sakai A, Takata T, Ueda T, Takino J, Tsutsumi M, Hyogo H, Yamagishi S.
- Journal Title
  
  Med. Hypotheses
  
  Volume: ８４ Issue: 5 Pages: 490-493
- DOI
  10.1016/j.mehy.2015.02.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25282029, KAKENHI-PROJECT-15K16239
[Journal Article] Toxic AGEs (TAGE) theory in the pathogenesis of NAFLD and ALD.2015
- Author(s)
  Takeuchi M, Sakasai-Sakai A, Takino J, Takata T, Ueda T, Tsutsumi M.
- Journal Title
  
  Int. J. Diabetes Clin. Res.
  
  Volume: ２ Pages: 4-4
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25282029
[Journal Article] 生活習慣病の発症・進展におけるToxic AGEs (TAGE) の関与：－新たな予防戦略－～食事性AGEsおよび糖毒性の真実～2015
- Author(s)
  竹内正義、瀧野純一、逆井（坂井）亜紀子、高田尊信、上田忠司
- Journal Title
  
  金医大誌
  
  Volume: ４０ Pages: 95-103
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25282029
[Journal Article] Involvement of the TAGE-RAGE system in NASH: Novel treatment strategies.2014
- Author(s)
  Takeuchi M, Takino J, Sakasai-Sakai A, Takata T, Ueda T, Tsutsumi M, Hyogo H, Yamagishi S.
- Journal Title
  
  World J. Hepatol
  
  Volume: 6 Issue: 12 Pages: 880-893
- DOI
  10.4254/wjh.v6.i12.880
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] 細胞内グリセルアルデヒド誘導体化HSP90は、心筋細胞障害を引き起こすか？2023
- Author(s)
  高田尊信
- Organizer
  第71回日本心臓病学会学術集会
- Data Source
  KAKENHI-PROJECT-21K11607
[Presentation] 心筋細胞の拍動低下および細胞死に関与するHeat Shock Protein 90 betaの糖化～グリセルアルデヒド誘導体化HSP90 betaの生成2023
- Author(s)
  高田尊信
- Organizer
  第23回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-21K11607
[Presentation] 毒性終末糖化産物（TAGE）が引き起こす心筋細胞および心臓線維芽細胞障害2022
- Author(s)
  高田尊信、逆井（坂井）亜紀子、竹内正義
- Organizer
  第70回日本心臓病学会学術集会
- Data Source
  KAKENHI-PROJECT-21K11607
[Presentation] ヒトの健康に対するToxic AGEs (TAGE) の影響2022
- Author(s)
  竹内正義、逆井（坂井）亜紀子、高田尊信、郡山恵樹、古川絢子、滝野純一、長嶺憲太郎、堀隆光、菊池千草、堀英生、岩尾岳洋、松永民秀
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K11607
[Presentation] 生活習慣病における新たな概念Toxc AGEs（TAGE）2022
- Author(s)
  竹内正義、逆井（坂井）亜紀子、高田尊信、瀧野純一、郡山恵樹、古川絢子、那須隆斗、菊池千草、長嶺憲太郎、堀隆光、松永民秀
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21K11607
[Presentation] 肝実質細胞内における毒性AGEs（TAGE）蓄積が酸化ストレスに及ぼす影響2021
- Author(s)
  逆井（坂井）亜紀子、高田尊信、瀧野純一、竹内正義
- Organizer
  第7回肝臓と糖尿病・代謝研究学会
- Data Source
  KAKENHI-PROJECT-21K11607
[Presentation] 細胞内Toxic AGEs（TAGE）の生成・蓄積は各種細胞障害のトリガーとなる2021
- Author(s)
  竹内正義、逆井（坂井）亜紀子、高田尊信、瀧野純一、郡山恵樹、菊池千草、古川絢子、長嶺憲太郎、堀隆光、松永民秀
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18K11139
[Presentation] 生活習慣病の発症・進展予防における新規概念Toxic AGEs（TAGE）と食事療法2021
- Author(s)
  高田尊信、逆井（坂井）亜紀子、瀧野純一、竹内正義
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21K11607
[Presentation] Accumulation of toxic advanced glycation end-products induces cell death and inhibits osteoblastic diffrentiation in MC3T3-E1 cells2021
- Author(s)
  逆井（坂井）亜紀子、高田尊信、竹内正義
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K11607
[Presentation] グリコーゲン代謝物1,5-アンヒドロ-D-フルクトース（1,5-AF）由来AGEsを捉える2020
- Author(s)
  逆井（坂井）亜紀子、高田尊信、鈴木宏一、丸山征郎、田中賢治、本宮善恢、竹内正義
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18K11139
[Presentation] 血糖コントロールマーカー1,5-AG前駆体1,5-Anhdydro-D-fructose (1,5-AF) 由来新規AGEsの生理作用2020
- Author(s)
  竹内正義、逆井（坂井）亜紀子、高田尊信、鈴木征郎、田中賢治、本宮善恢
- Organizer
  第74回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-18K11139
[Presentation] Intracellular toxic advanced glycation end-products promote the production of reactive oxygen species in HepG2 cells2020
- Author(s)
  逆井（坂井）亜紀子、高田尊信、竹内正義
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K11139
[Presentation] グリコーゲン代謝中間体1,5-Anhidro-D-fructose (1,5-AF) の生理的意味合い2020
- Author(s)
  高田尊信、逆井（坂井）亜紀子、鈴木宏一、丸山征郎、田中賢治、本宮善恢、竹内正義
- Organizer
  第20回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-18K11139
[Presentation] TAGEの生成・蓄積により誘導されるラット初代培養心筋細胞障害2018
- Author(s)
  高田尊信
- Organizer
  金沢医科大学医学会第54回学術集会
- Data Source
  KAKENHI-PROJECT-18K11139
[Presentation] Toxic AGEs (TAGE) は新規未病マーカー2018
- Author(s)
  竹内正義、逆井（坂井）亜紀子、高田尊信
- Organizer
  第25回日本未病システム学会学術総会
- Data Source
  KAKENHI-PROJECT-18K11139
[Presentation] 初代培養心筋、肝細胞における終末糖化産物の影響2017
- Author(s)
  上田忠司、高田尊信、竹内正義
- Organizer
  第１２２回日本解剖学会総会・全国学術集会
- Place of Presentation
  長崎大学坂本キャンパス（長崎県長崎市）
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16K12742
[Presentation] 培養心筋細胞における細胞内TAGE生成／蓄積と心筋細胞障害2016
- Author(s)
  上田忠司、高田尊信、竹内正義
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜 (神奈川県横浜市
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-26750056
[Presentation] ヒト膵管癌培養細胞における細胞内TAGE蓄積と細胞障害関連蛋白質の探索2016
- Author(s)
  高田尊信、逆井 (坂井) 亜紀子、上田忠司、竹内正義
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜 (神奈川県横浜市)
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-26750056
[Presentation] 培養心筋細胞における細胞内TAGE生成／蓄積と心筋細胞障2016
- Author(s)
  上田忠司、高田尊信、竹内正義
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25282029
[Presentation] ヒト膵管癌培養細胞における細胞内TAGE蓄積と細胞障害関連蛋白質の探索2016
- Author(s)
  高田尊信、逆井（坂井）亜紀子、上田忠司、竹内正義
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25282029

1. TAKEUCHI Masayoshi (20154982)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. UEDA Tadashi (80151794)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
3. TAKINO Jun-ichi (00440529)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. KORIYAMA Yoshiki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. FURUKAWA Ayako

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 逆井亜紀子

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
7. 石垣靖人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takata takanobu 高田 尊信

TAKATA Takanobu 高田 尊信

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The mechanisms of oral epithelial dysfunction based on advanced glycation end-products and screening of Kampo medicines for prevention and treatmentPrincipal Investigator

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Mechanisms of cytotoxicity due to the generation and accumulation of toxic advanced glycation end-prodcuts (TAGE) in cardiomyocytesPrincipal Investigator

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Elucidating the cardiomyocytes damage caused by Toxic Advanced Glycation End-products (TAGE) and the underlying mechanismPrincipal Investigator

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Excessive ingestion of sugar causes the abnomality of endoplasmic reticulum, resulting in providing for NASH

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Identification of the promoter proteins for pancreatic cancer which concurred with diabetes and research of effect of the compounds in citrus fruits which investigation is approached from AGEs.Principal Investigator

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Association between characteristics of current diet and onset/deterioration of non-alcoholic fatty liver disease

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[Book] アンチエイジングのための100の質問2014

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[Journal Article] Analysis of Crude, Diverse, and Multiple Advanced Glycation End-Product Patterns May Be Important and Beneficial2024

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[Journal Article] Novel In Vitro Assay of the Effects of Kampo Medicines against Intra/Extracellular Advanced Glycation End-Products in Oral, Esophageal, and Gastric Epithelial Cells2023

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[Journal Article] Is the Novel Slot Blot a Useful Method for Quantification of Intracellular Advanced Glycation End-Products?2023

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[Journal Article] Potential of the Novel Slot Blot Method with a PVDF Membrane for Protein Identification and Quantification in Kampo Medicines2023

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[Journal Article] Intracellular Toxic Advanced Glycation End-Products May Induce Cell Death and Suppress Cardiac Fibroblasts2022

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[Journal Article] Intracellular Toxic Advanced Glycation End-Products in 1.4E7 Cell Line Induce Death with Reduction of Microtubule-Associated Protein 1 Light Chain 3 and p622022

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[Journal Article] Effects of Toxic AGEs (TAGE) on Human Health2022

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Takata takanobu 高田尊信

TAKATA Takanobu 高田尊信