Ohmura Gaku 大村学

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ohmura gaku 大村学

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Researcher Number	20516182
Other IDs
Affiliation (Current)	2025: 京都府立医科大学, 医学(系)研究科(研究院), 特任助教
Affiliation (based on the past Project Information) *help	2022 – 2023: 京都府立医科大学, 医学(系)研究科(研究院), 特任助教 2019 – 2021: 京都府立医科大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / 0901:Oncology and related fields
Keywords	Principal Investigator バイオマーカー / 腫瘍免疫 / イメージング / 甲状腺濾胞癌 / 甲状腺癌 / 画像定量化技術 / 免疫組織化学 / 多重免疫染色 / 癌微小環境

Identification of capusular invasive mechanisms of follicular thyroid carcinoma via tumor microenvironment mappingPrincipal Investigator
- Principal Investigator
  
  大村学
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Identification of tumor immune microenvironment properties involved in the development and progression of follicular thyroid carcinomaPrincipal Investigator
- Principal Investigator
  
  ohmura gaku
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0901:Oncology and related fields
- Research Institution
  Kyoto Prefectural University of Medicine

All 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Immunomodulatory effect of induction chemotherapy on the oral cancer microenvironment2022
- Author(s)
  Tsujikawa Takahiro、Kimura Alisa、Morimoto Hiroki、Saburi Sumiyo、Mitsuda Junichi、Yoshimura Kanako、Mori Daichi、Ohmura Gaku、Mukudai Shigeyuki、Sugiyama Yoichiro、Hirano Shigeru
- Journal Title
  
  JOURNAL OF JAPAN SOCIETY FOR HEAD AND NECK SURGERY
  
  Volume: 32 Issue: 2 Pages: 117-120
- DOI
  10.5106/jjshns.32.117
- ISSN
  1349-581X, 1884-474X
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09688, KAKENHI-PROJECT-21K15536
[Journal Article] Spatially resolved immune microenvironmental profiling for follicular thyroid carcinoma with minimal capsular invasion2021
- Author(s)
  Saburi Sumiyo、Tsujikawa Takahiro、Miyagawa-Hayashino Aya、Mitsuda Junichi、Yoshimura Kanako、Kimura Alisa、Morimoto Hiroki、Ohmura Gaku、Arai Akihito、Ogi Hiroshi、Konishi Eiichi、Itoh Kyoko、Sugino Kiminori、Hirano Shigeru
- Journal Title
  
  Modern Pathology
  
  Volume: e-pub Issue: 6 Pages: 1-7
- DOI
  10.1038/s41379-021-00993-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K18814, KAKENHI-PROJECT-20K07411, KAKENHI-PROJECT-21K15536
[Journal Article] Extracellular acidity in tumor tissue upregulates programmed cell death protein-1 expression on tumor cells via proton‐sensing G protein‐coupled receptors2021
- Author(s)
  Mori Daichi、Tsujikawa Takahiro、Sugiyama Yoichiro、Kotani Shin‐ichiro、Fuse Shinya、Ohmura Gaku、Arai Akihito、Kawaguchi Tsutomu、Hirano Shigeru、Mazda Osam、Kishida Tsunao
- Journal Title
  
  International Journal of Cancer
  
  Volume: 149 Issue: 12 Pages: 2116-2124
- DOI
  10.1002/ijc.33786
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K18814, KAKENHI-PROJECT-21K15536
[Journal Article] Spatial Profiles of Intratumoral PD-1+ Helper T Cells Predict Prognosis in Head and Neck Squamous Cell Carcinoma2021
- Author(s)
  Yoshimura Kanako、Tsujikawa Takahiro、Mitsuda Junichi、Ogi Hiroshi、Saburi Sumiyo、Ohmura Gaku、Arai Akihito、Shibata Saya、Thibault Guillaume、Chang Young Hwan、Clayburgh Daniel R.、Yasukawa Satoru、Miyagawa-Hayashino Aya、Konishi Eiichi、Itoh Kyoko、Coussens Lisa M.、Hirano Shigeru
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 12 Pages: 4554-4554
- DOI
  10.3389/fimmu.2021.769534
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K18814, KAKENHI-PROJECT-20K07411, KAKENHI-PROJECT-21K15536
[Journal Article] A 14-Marker Multiplexed Imaging Panel for Prognostic Biomarkers and Tumor Heterogeneity in Head and Neck Squamous Cell Carcinoma2021
- Author(s)
  Mitsuda Junichi、Tsujikawa Takahiro、Yoshimura Kanako、Saburi Sumiyo、Suetsugu Masaho、Kitamoto Kayo、Takenaka Mari、Ohmura Gaku、Arai Akihito、Ogi Hiroshi、Itoh Kyoko、Hirano Shigeru
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 11 Pages: 3002-3002
- DOI
  10.3389/fonc.2021.713561
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18814, KAKENHI-PROJECT-21K15536
[Journal Article] 免疫的癌微小環境解析を通じた頭頸部癌薬物療法の治療効果予測2020
- Author(s)
  辻川敬裕, 吉村佳奈子, 光田順一, 佐分利純代, 竹中まり, 大村　学, 新井啓仁, 荻　寛志, 宮川　文, 小西英一, 伊東恭子, 平野　滋
- Journal Title
  
  頭頸部癌
  
  Volume: 45 Pages: 362-365
- NAID
  130007851654
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K23893
[Presentation] Tumor-immune microenvironmental profiling during chemo- and targeted therapy for head and neck squamous cell carcinoma.2023
- Author(s)
  Kimura A, Tsujikawa T, Mitsuda J, Morimot H, Saburi S, Yoshimura K, Ohmura G, Mukudai S, Nagao H, Sugiyama Y, Ogi H, Shiabata S, Itoh K, Hirano S.
- Organizer
  American Association for Cancer Research Annual Meeting 2023.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15536
[Presentation] 頭頸部癌のペムブロリズマブ投与症例における好中球/リンパ球比(NLR)の動態と腫瘍免疫環境との関連の検討.2023
- Author(s)
  森本寛基, 辻川敬裕, 木村有佐, 佐分利純代, 大村　学, 椋代茂之, 永尾　光, 杉山庸一郎, 平野　滋.
- Organizer
  第47回日本頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-21K15536
[Presentation] Neutrophil-to-lymphocyte ratio (NLR) associates with intra tumoral myeloid predominance and clinical outcomes of pembrolizumab in head and neck squamous cell carcinoma.2023
- Author(s)
  Morimoto H, Tsujikawa T, Miyagawa-Hayashino A, Kimura A, Saburi S, Mitsuda J, Yoshimura K, Ohmura G, Mukudai S, Nagao H, Sugiyama Y, Shiabata S, Ogi H, Itoh K, Hirano S.
- Organizer
  American Association for Cancer Research Annual Meeting 2023.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15536
[Presentation] Tumor immune characterization identifies age-stratified biomarkers for nivolumab in patients with head and neck squamous cell carcinoma: A nationwide collaborative study in Japan.2022
- Author(s)
  Tsujikawa T, Ohno K, Saburi S, Mitsuda J, Yoshimura K, Kimura A, Morimoto H, Ohmura G, et al
- Organizer
  American Association for Cancer Research Annual Meeting 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15536
[Presentation] 酸性腫瘍微小環境はpH感知性チャネルを介して頭頸部癌のPD-L1発現に関わる2022
- Author(s)
  森　大地, 辻川敬裕, 杉山庸一郎, 小谷晋一郎, 布施慎也, 大村　学, 松田　修, 岸田綱郎, 平野　滋.
- Organizer
  第123回日本耳鼻咽喉科頭頸部外科学会
- Data Source
  KAKENHI-PROJECT-21K15536
[Presentation] 頭頸部癌への抗EGFR治療を含む導入化学療法における癌免疫微小環境の変動.2022
- Author(s)
  辻川敬裕, 木村有佐, 森本寛基, 佐分利純代, 光田順一, 吉村佳奈子, 大村学.
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K15536
[Presentation] PCE療法前後における免疫的がん微小環境特性とPD-L1発現の変化.2022
- Author(s)
  木村有佐, 辻川敬裕, 光田順一, 吉村佳奈子, 森本寛基, 佐分利純代, 大村　学, 椋代茂之, 杉山庸一郎, 平野　滋.
- Organizer
  第46回日本頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-21K15536
[Presentation] Extracellular acidity in tumor tissue upregulates PD-L1 expression on tumor cells via proton-sensing G protein-coupled receptors.2022
- Author(s)
  森　大地, 辻川敬裕, 大村　学, 松田　修, 岸田綱郎.
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K15536
[Presentation] 甲状腺濾胞がん被膜浸潤と関連する免疫微小環境特性.2021
- Author(s)
  佐分利純代, 光田順一, 吉村佳奈子, 木村有佐, 森本寛基, 大村　学, 辻川敬裕.
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K15536
[Presentation] patially-resolved immune microenvironmental profiles of follicular thyroid carcinoma.2021
- Author(s)
  3)Saburi S, Tsujikawa T, Miyagawa-Hayashino A, Mitsuda J, Yoshimura K, Kimura A, Morimoto H, Ohmura G, Arai A, Ogi H, Konishi E, Itoh K, Sugino K, Hirano S.
- Organizer
  JCA-AACR Precision Cancer Medicine International Conference 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15536
[Presentation] 中咽頭癌における腫瘍内T細胞の細胞特性と局在の予後的意義.2021
- Author(s)
  1)吉村佳奈子, 辻川敬裕, 光田順一, 佐分利純代, 木村有佐, 森本寛基, 大村学, 新井啓仁, 平野　滋.
- Organizer
  第122回日本耳鼻咽喉科学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-21K15536
[Presentation] 内頸静脈腫瘍栓塞・頭蓋底浸潤により多発神経障害を来した甲状腺癌症例2020
- Author(s)
  松下大樹，大村　学，光田順一，辻川敬裕，新井啓仁，平野　滋
- Organizer
  第82回耳鼻咽喉科臨床学会
- Data Source
  KAKENHI-PROJECT-19K23893
[Presentation] 頭頸部癌メタ解析に基づく癌細胞多重免疫染色パネルによる悪性形質・腫瘍不均一性の検討2020
- Author(s)
  光田順一，辻川敬裕，吉村佳奈子，佐分利純代，Machuca Ostos Mercedes，竹中まり，大村　学，新井啓仁，平野　滋
- Organizer
  第44回日本頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-19K23893
[Presentation] 化学放射線治療後の局所再発と相関する頭頸部癌免疫的微小環境特性の解析2020
- Author(s)
  辻川敬裕，Grace Banik，光田順一，吉村佳奈子，佐分利純代，竹中まり，大村　学，新井啓仁，Daniel R. Clayburgh，Lisa M. Coussens，平野　滋
- Organizer
  第30回日本頭頸部外科学会総会
- Data Source
  KAKENHI-PROJECT-19K23893
[Presentation] 頭頸部神経鞘腫の手術症例の検討2020
- Author(s)
  佐分利純代，新井啓仁，吉村佳奈子，光田順一，竹中まり，大村　学，辻川敬裕，平野　滋
- Organizer
  第30回日本頭頸部外科学会総会
- Data Source
  KAKENHI-PROJECT-19K23893
[Presentation] 術中経食道エコーが誘引となった声門下肉芽腫の２例2020
- Author(s)
  森　大地，宗川亮人，大村　学，為野仁輔，山本　聡
- Organizer
  第30回日本頭頸部外科学会総会
- Data Source
  KAKENHI-PROJECT-19K23893
[Presentation] 術前PCE療法による舌癌縮小手術の可能性2020
- Author(s)
  新井啓仁，光田順一，吉村佳奈子，佐分利純代，大村　学，竹中まり，辻川敬裕，平野　滋
- Organizer
  第30回日本頭頸部外科学会総会
- Data Source
  KAKENHI-PROJECT-19K23893
[Presentation] 遊離空腸再建症例５２例における術後合併症とリスク因子の検討2020
- Author(s)
  大村　学，川勝大河，光田順一，吉村佳奈子，佐分利純代，竹中まり，辻川敬裕，新井啓仁，平野　滋
- Organizer
  第30回日本頭頸部外科学会総会
- Data Source
  KAKENHI-PROJECT-19K23893
[Presentation] Intratumoral T cell characterization for identification of biomarkers in head and neck cancer2020
- Author(s)
  マチュアカオストス　メルセデス，辻川敬裕，光田順一，吉村佳奈子，佐分利純代，竹中まり，大村　学，新井啓仁，平野　滋
- Organizer
  第44回日本頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-19K23893
[Presentation] 頭頸部癌微小環境におけるヘルパー T 細胞の腫瘍内局在と予後的影響の検討2019
- Author(s)
  吉村佳奈子, 辻川敬裕, 光田順一, 佐分利純代, 竹中まり, 大村　学, 新井啓仁, 平野滋
- Organizer
  第43回日本頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-19K23893
[Presentation] 下咽頭癌に対する経口切除後の嚥下障害症例の検討2019
- Author(s)
  佐分利純代, 吉澤宏一, 吉村佳奈子, 光田順一, 辻川敬裕, 竹中まり, 大村　学, 新井啓仁, 杉山庸一郎, 平野滋
- Organizer
  第43回日本頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-19K23893
[Presentation] 術前化学療法として PCE 療法を施行した口腔癌症例の検討2019
- Author(s)
  新井啓仁, 竹中まり, 吉村佳奈子, 光田順一, 佐分利純代, 大村　学, 辻川敬裕, 杉山庸一郎, 平野滋
- Organizer
  第43回日本頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-19K23893
[Presentation] 頸部に発生した異所性胸腺腫の１例2019
- Author(s)
  松本藍, 光田順一, 吉村佳奈子, 佐分利純代, 高島康利, 北條智人, 薗部優大, 村田晋一, 岸本光夫, 小西英一, 竹中まり, 大村学, 辻川敬裕, 新井啓仁, 平野滋
- Organizer
  第133回日耳鼻京滋合同地方部会
- Data Source
  KAKENHI-PROJECT-19K23893
[Presentation] 遊離空腸再建症例における術後経口摂取状況とリスク因子の検討2019
- Author(s)
  豊田拓司, 大村学, 川勝大河, 吉村佳奈子, 光田順一, 佐分利純代, 小西博貴, 塩崎敦, 藤原斉, 竹中まり, 辻川敬裕, 新井啓仁, 平野滋
- Organizer
  第134回日耳鼻京滋合同地方部会
- Data Source
  KAKENHI-PROJECT-19K23893
[Presentation] 当科における甲状腺腫瘍手術症例の検討2019
- Author(s)
  大村　学，為野仁輔，森　大地
- Organizer
  第43回日本頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-19K23893
[Presentation] 組織バイオマーカーのメタアナリシスに基づいた頭頸部扁平上皮癌の悪性形質の解析2019
- Author(s)
  光田順一, 辻川敬裕, 吉村佳奈子, 佐分利純代, 竹中まり, 大村　学, 新井啓仁, 平野滋
- Organizer
  第43回日本頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-19K23893

1. 辻川敬裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results

Ohmura Gaku 大村 学

ohmura gaku 大村 学

Research Projects

Research Products

Co-Researchers

Identification of capusular invasive mechanisms of follicular thyroid carcinoma via tumor microenvironment mappingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of tumor immune microenvironment properties involved in the development and progression of follicular thyroid carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Immunomodulatory effect of induction chemotherapy on the oral cancer microenvironment2022

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Spatially resolved immune microenvironmental profiling for follicular thyroid carcinoma with minimal capsular invasion2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Extracellular acidity in tumor tissue upregulates programmed cell death protein-1 expression on tumor cells via proton‐sensing G protein‐coupled receptors2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Spatial Profiles of Intratumoral PD-1+ Helper T Cells Predict Prognosis in Head and Neck Squamous Cell Carcinoma2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A 14-Marker Multiplexed Imaging Panel for Prognostic Biomarkers and Tumor Heterogeneity in Head and Neck Squamous Cell Carcinoma2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 免疫的癌微小環境解析を通じた頭頸部癌薬物療法の治療効果予測2020

Author(s)

Journal Title

NAID

Data Source

[Presentation] Tumor-immune microenvironmental profiling during chemo- and targeted therapy for head and neck squamous cell carcinoma.2023

Author(s)

Organizer

Data Source

[Presentation] 頭頸部癌のペムブロリズマブ投与症例における好中球/リンパ球比(NLR)の動態と腫瘍免疫環境との関連の検討.2023

Author(s)

Organizer

Data Source

[Presentation] Neutrophil-to-lymphocyte ratio (NLR) associates with intra tumoral myeloid predominance and clinical outcomes of pembrolizumab in head and neck squamous cell carcinoma.2023

Author(s)

Organizer

Data Source

[Presentation] Tumor immune characterization identifies age-stratified biomarkers for nivolumab in patients with head and neck squamous cell carcinoma: A nationwide collaborative study in Japan.2022

Author(s)

Organizer

Data Source

[Presentation] 酸性腫瘍微小環境はpH感知性チャネルを介して頭頸部癌のPD-L1発現に関わる2022

Author(s)

Organizer

Data Source

[Presentation] 頭頸部癌への抗EGFR治療を含む導入化学療法における癌免疫微小環境の変動.2022

Author(s)

Organizer

Data Source

[Presentation] PCE療法前後における免疫的がん微小環境特性とPD-L1発現の変化.2022

Author(s)

Organizer

Data Source

[Presentation] Extracellular acidity in tumor tissue upregulates PD-L1 expression on tumor cells via proton-sensing G protein-coupled receptors.2022

Author(s)

Organizer

Ohmura Gaku 大村学

ohmura gaku 大村学