Tsuboi Shigeru 坪井滋

… Alternative Names

TSUBOI Shigeru 坪井滋

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Researcher Number	20526727
Affiliation (Current)	2025: 弘前大学, 医学研究科, 研究員
Affiliation (based on the past Project Information) *help	2018 – 2022: 弘前大学, 医学研究科, 研究員 2017: 弘前大学, 医学研究科, 客員研究員 2014 – 2016: 弘前大学, 医学研究科, 研究員 2012 – 2015: 弘前大学, 医学(系)研究科(研究院), 研究員 2010 – 2011: 弘前大学, 大学院・医学研究科, 研究員
Review Section/Research Field	Principal Investigator Functional biochemistry Except Principal Investigator Urology / Medium-sized Section 50:Oncology and related fields
Keywords	Principal Investigator 膀胱癌 / 腫瘍免疫 / O-グリカン / リンパ節転移 / 細胞傷害性Tリンパ球(CTL) / 転移 / 細胞傷害性Tリンパ球 / 前立腺癌 / ＮＫ細胞 / 前立腺がん … More / 膀胱がん / 免疫 / 糖鎖生物学 / NK細胞 / 癌転移 … More Except Principal Investigator 糖鎖 / バイオマーカー / 前立腺癌 / レクチン / 診断 / 前立腺特異抗原 / 分子標的 / 中性子補足療法 / 放射線治療 / ドラッグデリバリーシステム / 中性子捕捉療法 / ホウ素中性子補助療法 / 糖鎖生物学 / 薬物送達 / ホウ素中性子補足療法 / 血管内皮細胞 / 腫瘍マーカー / PSA / 前立腺がん / 再発予測 / 1前立腺癌 / 糖タンパク / 悪性度診断法 / マーカー Less

Development of molecular targeted boron neutron capture therapy
- Principal Investigator
  
  Ohyama Chikara
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Hirosaki University
A novel mechanism for evasion of CTL immunity by altered O-glycosylationPrincipal Investigator
- Principal Investigator
  
  TSUBOI Shigeru
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Hirosaki University
Practical application of glycan-targeted biomarker to prevent over-diagnosis and over-treatment of prostate cancer
- Principal Investigator
  
  Ohyama Chikara
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Urology
- Research Institution
  Hirosaki University
A new glyco-biomarker for comprehensive evaluation of malignant potential in prostate cancer
- Principal Investigator
  
  OHYAMA Chikara
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Urology
- Research Institution
  Hirosaki University
Development of glycan-targetted assay system for diagnosis of prostate cancer
- Principal Investigator
  
  OHYAMA Chikara
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Hirosaki University
Immune evasion mechanisms from NK immunity by cancer cell-surface O-glycansPrincipal Investigator
- Principal Investigator
  
  TSUBOI Shigeru
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Hirosaki University

All 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Book Patent

[Book] Handbook of Glycosyltransferases and Related Genes Beta-1,3-galactosyl-O-glycosyl-gly Coprotein beta-1,6-N-acetylglucosaminyltras nsferase 1 (GCNT1) (C2GnT-L) and Beta-1,3-galactosyl-O-glycosyl-gly coprotein beta-1,6-N-acetylglucosaminyltras nsferase 3 (GCNT4) (C2GnT-T)2014
- Author(s)
  Shigeru Tsuboi(分担執筆)(Eds. by Naoyuki Taniguchi, Koichi Honke, Minoru Fukuda, Hisashi Narimatsu, Yoshiki Yamaguchi and Takashi Angata)
- Publisher
  Springer
- URL
  http://www.springerreference.com/docs/html/chapterdbid/332082.html
- Data Source
  KAKENHI-PROJECT-22570131
[Book] Handbook of Glycosyltransferases and Related Genes2014
- Author(s)
  Tsuboi, S. and Fukuda, M.
- Total Pages
  5
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-22570131
[Journal Article] A mechanism for evasion of CTL immunity by altered O-glycosylation of HLA class I.2017
- Author(s)
  Yoneyama MS, Tobisawa Y, Hatakeyama S, Sato M, Tone K, Tatara Y, Kakizaki I, Funyu T, Fukuda M, Hoshi S, Ohyama C, Tsuboi S
- Journal Title
  
  J Biochem.
  
  Volume: 印刷中 Pages: 479-492
- DOI
  10.1093/jb/mvw096
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25220206, KAKENHI-PROJECT-15H02563, KAKENHI-PROJECT-15K06989
[Journal Article] Invadopodia play an essential role in transendothelial invasion during muscle invasion of bladder cancer cells2014
- Author(s)
  Imanishi, K., Sutoh Yoneyama, M.,Hatakeyama, S., Yamamoto, H., Koie, T.,Saitoh, H., Yamaya, K., Funyu, T.,Nakamura, T., Ohyama, C. and Tsuboi,S.
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: (in press) Issue: 6 Pages: 2159-2165
- DOI
  10.3892/mmr.2014.2113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570131, KAKENHI-PROJECT-23791737
[Journal Article] Extravasation during bladder cancer metastasis requires cortactin-mediated invadopodia formation2014
- Author(s)
  Tokui, N., Sutoh Yoneyama, M.,Hatakeyama, S., Yamamoto, H., Koie, T.,Saitoh, H., Yamaya, K., Funyu, T.,Nakamura, T., Ohyama, C. and Tsuboi,S.
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: 9 Issue: 4 Pages: 1142-1146
- DOI
  10.3892/mmr.2014.1965
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570131, KAKENHI-PROJECT-23791737
[Journal Article] Vimentin intermediate filament and plectin provide a scaffold for invadopodia, facilitating cancer cell invasion and extravasation for metastasis.2014
- Author(s)
  Sutoh Yoneyama, M., Hatakeyama, S., Habuchi, T., Inoue, T., Nakamura, T., Funyu, T., Wiche, G., Ohyama, C. and *Tsuboi, S.
- Journal Title
  
  European Journal of Cell Biology
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570131
[Journal Article] Vimentin intermediate filament and plectin provide a scaffold for invadopodia, facilitating cancer cell invasion and extravasation for metastasis2014
- Author(s)
  Sutoh Yoneyama, M., Hatakeyama, S.,Habuchi, T., Inoue, T., Nakamura, T.,Funyu, T., Wiche, G., Ohyama, C. and Tsuboi, S.
- Journal Title
  
  European Journal of Cell Biology
  
  Volume: (in press) Issue: 4 Pages: 157-169
- DOI
  10.1016/j.ejcb.2014.03.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570131, KAKENHI-PROJECT-23791737
[Journal Article] Ｏ-グリカンによる膀胱癌の新規免疫逃避機構2013
- Author(s)
  坪井　滋、畠山真吾、大山　力
- Journal Title
  
  病理と臨床
  
  Volume: 13 Pages: 868-874
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570131
[Journal Article] Misfolded Glycoproteins as Probes for Analysis of Folding Sensor Enzyme UDP-Glucose2013
- Author(s)
  Tsuboi, S.
- Journal Title
  
  Trends in Glycoscience and Glycotechnology
  
  Volume: 25 Issue: 141 Pages: 1-12
- DOI
  10.4052/tigg.25.1
- NAID
  130004841363
- ISSN
  0915-7352, 1883-2113
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570131, KAKENHI-PROJECT-23245037
[Journal Article] Immunosuppressive Functions of Core2 <i>O</i>-Glycans against NK Immunity2013
- Author(s)
  Tsuboi, S.
- Journal Title
  
  Trends in Glycoscience and Glycotechnology
  
  Volume: 25 Issue: 143 Pages: 117-123
- DOI
  10.4052/tigg.25.117
- NAID
  10031190627
- ISSN
  0915-7352, 1883-2113
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570131
[Journal Article] In vivo selection of high-metastatic subline of bladder cancer cell and itscharacterization2013
- Author(s)
  Sugiyama, N., Sutoh Yoneyama, M.,Hatakeyama, S., Yamamoto, H.,Okamoto, A., Koie, T., Saitoh, H.,Yamaya, K., Funyu, T., Nakamura, T.,Ohyama, C. and Tsuboi, S.
- Journal Title
  
  Oncology Research
  
  Volume: 20 Issue: 7 Pages: 289-295
- DOI
  10.3727/096504013x13639794277644
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570131
[Journal Article] O-グリカンによる膀胱癌の新規免疫逃避機構2013
- Author(s)
  坪井滋、畠山真吾、大山力
- Journal Title
  
  病理と臨床
  
  Volume: 31(8) Pages: 868-874
- Data Source
  KAKENHI-PROJECT-22570131
[Journal Article] Core2 O-glycan-expressing prostate cancer cells are resistant to NK cell immunity.2013
- Author(s)
  Okamoto T，Yoneyama MS，Hatakeyama S，Mori K，Yamamoto H，Koie T，Saitoh H，Yamaya K，Funyu T，Fukuda M，Ohyama C，Tsuboi S
- Journal Title
  
  Mol Med Rep
  
  Volume: 7 Pages: 359-364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659708
[Journal Article] Core2 O-glycan-expressing prostate cancer cells are resistant to NK cell immunity2013
- Author(s)
  Okamoto, T., Sutoh Yoneyama, M.,Hatakeyama, S., Mori, K., Yamamoto, H.,Koie, T., Saitoh, H., Yamaya, K., Funyu,T., Fukuda, M., Ohyama, C. and Tsuboi,S.
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: 7 Issue: 2 Pages: 359-364
- DOI
  10.3892/mmr.2012.1189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570131, KAKENHI-PROJECT-24592372
[Journal Article] Two opposing roles of O-glycans in tumor metastasis2012
- Author(s)
  Tsuboi, S., Hatakeyama, S., Ohyama,C. and Fukuda, M.
- Journal Title
  
  Trends in Molecular Medicine
  
  Volume: 18 Issue: 4 Pages: 224-232
- DOI
  10.1016/j.molmed.2012.02.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570131, KAKENHI-PROJECT-23791737
[Journal Article] MUC1 carrying core 2 O-glycans functions as a molecular shield against NK cell attack, promoting bladder tumor metastasis2012
- Author(s)
  Suzuki Y, et al.
- Journal Title
  
  International Journal of Onocology
  
  Volume: (未定)(in press) Pages: 1831-1838
- DOI
  10.3892/ijo.2012.1411
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390302, KAKENHI-PROJECT-22570131, KAKENHI-PROJECT-23659752, KAKENHI-PROJECT-23791737, KAKENHI-PROJECT-24592372
[Journal Article] Tumor Defense Systems Using <i>O</i>-Glycans2012
- Author(s)
  Tsuboi, S.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 35 Issue: 10 Pages: 1633-1636
- DOI
  10.1248/bpb.b12-00367
- NAID
  130001872366
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570131
[Journal Article] A novel strategy for evasion of NK cell immunity by tumours expressing core2 O-glycans2011
- Author(s)
  Tsuboi S, Sutoh M, Ohyama C., et al
- Journal Title
  
  EMBO J
  
  Volume: 30 Pages: 3173-3185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390301
[Journal Article] A novel strategy for evasion of NK cell immunity by tumours expressing core2 O-glycans2011
- Author(s)
  坪井滋、盛和行, 他
- Journal Title
  
  EMBO J
  
  Volume: 30(15) Issue: 15 Pages: 3173-3185
- DOI
  10.1038/emboj.2011.215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591848, KAKENHI-PROJECT-22390301, KAKENHI-PROJECT-22390302, KAKENHI-PROJECT-22570131, KAKENHI-PROJECT-23791737
[Journal Article] Requirement for FBP17 in invadopodia formation by invasive bladder tumor cells2011
- Author(s)
  Yamamoto, H., Sutoh, M., Hatakeyama,S., Hashimoto, Y.,Yoneyama, T., Koie, T.,Saitoh, H., Yamaya, K., Funyu, T.,Nakamura, T., Ohyama, C. and Tsuboi,S.
- Journal Title
  
  Journal of Urology
  
  Volume: 185 Issue: 5 Pages: 1930-1938
- DOI
  10.1016/j.juro.2010.12.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570131, KAKENHI-PROJECT-23791737
[Journal Article] Invadopodia formation by bladder tumor cells.2010
- Author(s)
  Sutoh M, Ohyama C, Tsuboi S., et al.
- Journal Title
  
  Oncol Res
  
  Volume: 19 Pages: 85-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390301
[Journal Article] Invadopodia formation by bladder tumor cells2010
- Author(s)
  Sutoh, M., Hashimoto, Y.,Yoneyama, T.,Yamamoto, H., Hatakeyama, S., Koie, T.,Okamoto, A., Yamaya, K., Saitoh, H.,Funyu, T., Nakamura, T., Sato, T.,Ohyama, C. and Tsuboi, S.
- Journal Title
  
  Oncology Research
  
  Volume: 19 Issue: 2 Pages: 85-92
- DOI
  10.3727/096504010x12875107808008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570131
[Patent] 特許権2010
- Inventor(s)
  大山力, 坪井滋
- Industrial Property Rights Holder
  弘前大学
- Industrial Property Number
  2010-182641
- Filing Date
  2010-08-17
- Acquisition Date
  2010
- Data Source
  KAKENHI-PROJECT-22570131
[Patent] siRNAおよびこれを用いたC2GnT-I RNA合成阻害法ならびに癌治療剤2010
- Inventor(s)
  大山力, 坪井滋
- Industrial Property Rights Holder
  弘前大学
- Industrial Property Number
  2010-182641
- Filing Date
  2010-08-17
- Data Source
  KAKENHI-PROJECT-22390301
[Patent] 特許権2010
- Inventor(s)
  大山力、坪井滋
- Industrial Property Rights Holder
  弘前大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2010-182641
- Filing Date
  2010-08-17
- Overseas
- Data Source
  KAKENHI-PROJECT-22570131
[Presentation] O-グリカン修飾変化を利用した新規CTL腫瘍免疫逃避機構．2017
- Author(s)
  米山美穂子，飛澤悠葵，畠山真吾，佐藤美紗季，刀禰亀代志，多田羅洋太，柿崎育子，舟生富寿，福田　穰，星　宣次，大山　力，坪井　滋
- Organizer
  東北糖鎖研究会・東京糖鎖研究会合同シンポジウム（第11回東北糖鎖研究会・Glyco TOKYO 2017）
- Data Source
  KAKENHI-PROJECT-15H02563
[Presentation] Bladder cancer-secreted extracellular vesicles destroy vascular endothelial barriers．2017
- Author(s)
  Yoneyama MS, Hatakeyama S ,Funyu T, Tsuboi S, Ohyama C
- Organizer
  第32回欧州泌尿器科学会（EAU）
- Place of Presentation
  ロンドン（イギリス）
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15H02563
[Presentation] O-グリカン修飾変化を利用した膀胱癌細胞の新規CTL腫瘍免疫逃避機構2016
- Author(s)
  坪井　滋
- Organizer
  第10回東北糖鎖研究会
- Place of Presentation
  コラッセふくしま（福島県福島市）
- Year and Date
  2016-08-06
- Data Source
  KAKENHI-PROJECT-15K06989
[Presentation] Stabilization of invadopodia by plectin-mediated conjunction to vimentin intermediate filament is a critical molecular step of invasion and extravasation for metastasis in bladder cancer.2016
- Author(s)
  Yoneyama MS, Hatakeyama S, Habuchi T, Inoue T, Nakamura T, Funyu T, Wiche G, Tsuboi S, Ohyama C
- Organizer
  第110回米国泌尿器科学会議(AUA2016)
- Place of Presentation
  サンディエゴ（アメリカ合衆国）
- Year and Date
  2016-05-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02563
[Presentation] 細胞表面糖鎖の修飾変化を利用した腫瘍免疫逃避機構2015
- Author(s)
  坪井　滋
- Organizer
  第８８回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K06989
[Presentation] 膀胱癌細胞の血管外脱出過程の解析2014
- Author(s)
  坪井　滋
- Organizer
  第１５１回弘前医学会例会
- Place of Presentation
  青森県弘前市
- Data Source
  KAKENHI-PROJECT-22570131
[Presentation] 糖鎖による癌の免疫逃避機構2013
- Author(s)
  坪井　滋
- Organizer
  第３２回日本糖質学会
- Place of Presentation
  大阪市
- Invited
- Data Source
  KAKENHI-PROJECT-22570131
[Presentation] Vimentin intermediate filament and plectin provide a scaffold for invadopodia, facilitating cancer cell invasion2013
- Author(s)
  Tsuboi, S.
- Organizer
  Invadosome 2013
- Place of Presentation
  Nijmegen, The Netherlands
- Data Source
  KAKENHI-PROJECT-22570131
[Presentation] Plectin 1 anchoring invadopodia to vimentin intermediate filament is a critical molecular step for cancer cell extaravasation and metastasis2013
- Author(s)
  坪井　滋
- Organizer
  第６５回日本細胞生物学会大会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-22570131
[Presentation] Vimentin intermediate filament and plectin provide a scaffold for invadopodiam, facilitating cancer cell invasion2013
- Author(s)
  Tsuboi, S.
- Organizer
  Invadosome 2013 Cell Migration and Invasion inPhysiology and Pathology
- Place of Presentation
  Radboud University Medical Center, Nijmegen, The Netherlands
- Year and Date
  2013-10-15
- Data Source
  KAKENHI-PROJECT-22570131
[Presentation] 糖鎖を利用した癌細胞自己防御システム2012
- Author(s)
  坪井滋
- Organizer
  東北薬科大学分子生体膜研究所戦略的研究基盤形成支援事業シンポジウム
- Place of Presentation
  東北薬科大学仙台
- Year and Date
  2012-11-03
- Data Source
  KAKENHI-PROJECT-22570131
[Presentation] 細胞表面のO-glycanを利用した癌細胞の新しい免疫逃避機構2011
- Author(s)
  坪井滋
- Organizer
  第77回生化学会東北支部会
- Place of Presentation
  仙台(東北大学)
- Year and Date
  2011-07-23
- Data Source
  KAKENHI-PROJECT-22570131
[Presentation] 細胞表面のO-glycanを利用した癌細胞の新しい免疫逃避機構2010
- Author(s)
  坪井滋
- Organizer
  第83回日本生化学会大会
- Place of Presentation
  神戸(神戸ポートアイランド)
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22570131
[Presentation] O-グリカンによる癌の免疫逃避機構
- Author(s)
  坪井　滋
- Organizer
  第６回東北糖鎖研究会
- Place of Presentation
  弘前（弘前大学）
- Data Source
  KAKENHI-PROJECT-22570131
[Presentation] 糖鎖を利用した癌細胞自己防御システム
- Author(s)
  坪井　滋
- Organizer
  東北薬科大学分子生体膜研究所　戦略的研究基盤形成支援事業シンポジウム
- Place of Presentation
  仙台（東北薬科大学）
- Invited
- Data Source
  KAKENHI-PROJECT-22570131

1. OHYAMA Chikara (80282135)

# of Collaborated Projects: 6 results

# of Collaborated Products: 18 results
2. MORI Kazuyuki (40266903)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
3. KOIE Takuya (60321965)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
4. HATAKEYAMA Shingo (10400136)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
5. YONEYAMA Tohru (50587649)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
6. HABUCHI Tomonori (00293861)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. 橋本安弘 (60322939)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 米山高弘 (90374834)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
9. KAMIMURA Noritaka (00281931)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KAKIZAKI Ikuko (80302024)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 西村紳一郎 (00183898)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 飛澤悠葵 (70623768)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 山本勇人 (30532759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 青木昌彦 (70292141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 石山新太郎 (60355021)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Tsuboi Shigeru 坪井 滋

TSUBOI Shigeru 坪井 滋

Research Projects

Research Products

Co-Researchers

Development of molecular targeted boron neutron capture therapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A novel mechanism for evasion of CTL immunity by altered O-glycosylationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Practical application of glycan-targeted biomarker to prevent over-diagnosis and over-treatment of prostate cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

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A new glyco-biomarker for comprehensive evaluation of malignant potential in prostate cancer

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Development of glycan-targetted assay system for diagnosis of prostate cancer

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Immune evasion mechanisms from NK immunity by cancer cell-surface O-glycansPrincipal Investigator

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[Book] Handbook of Glycosyltransferases and Related Genes Beta-1,3-galactosyl-O-glycosyl-gly Coprotein beta-1,6-N-acetylglucosaminyltras nsferase 1 (GCNT1) (C2GnT-L) and Beta-1,3-galactosyl-O-glycosyl-gly coprotein beta-1,6-N-acetylglucosaminyltras nsferase 3 (GCNT4) (C2GnT-T)2014

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[Book] Handbook of Glycosyltransferases and Related Genes2014

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[Journal Article] A mechanism for evasion of CTL immunity by altered O-glycosylation of HLA class I.2017

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[Journal Article] Invadopodia play an essential role in transendothelial invasion during muscle invasion of bladder cancer cells2014

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[Journal Article] Extravasation during bladder cancer metastasis requires cortactin-mediated invadopodia formation2014

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[Journal Article] Vimentin intermediate filament and plectin provide a scaffold for invadopodia, facilitating cancer cell invasion and extravasation for metastasis.2014

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[Journal Article] Vimentin intermediate filament and plectin provide a scaffold for invadopodia, facilitating cancer cell invasion and extravasation for metastasis2014

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[Journal Article] Ｏ-グリカンによる膀胱癌の新規免疫逃避機構2013

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[Journal Article] Misfolded Glycoproteins as Probes for Analysis of Folding Sensor Enzyme UDP-Glucose2013

Tsuboi Shigeru 坪井滋

TSUBOI Shigeru 坪井滋