Shinohara Kyosuke 篠原恭介

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SHINOHARA Kyosuke 篠原恭介

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Researcher Number	20527387
Other IDs
Affiliation (Current)	2025: 東京農工大学, 工学(系)研究科(研究院), 教授
Affiliation (based on the past Project Information) *help	2020 – 2025: 東京農工大学, 工学(系)研究科(研究院), 准教授 2017 – 2019: 東京農工大学, 工学(系)研究科(研究院), 特任准教授 2011 – 2014: 大阪大学, 生命機能研究科, 助教 2012: 大阪大学, 生命機能研究科, その他
Review Section/Research Field	Principal Investigator Basic Section 43030:Functional biochemistry-related / Developmental biology / Transformative Research Areas, Section (IV) / Science and Engineering / Functional biochemistry Except Principal Investigator Transformative Research Areas, Section (IV)
Keywords	Principal Investigator 繊毛 / 細胞骨格 / ウイルス / 細菌 / 呼吸器 / ミドリムシ / 精子 / 気道繊毛 / 細胞運動 / 環境応答 … More / 細胞外環境 / 気道繊毛細胞 / 繊毛細胞 / 気道 / 新型コロナウイルス / 気道繊毛運動 / 細胞夾雑 / 神経変性疾患 / 神経変性疾患モデル / 脱凝集因子 / 分子夾雑 / 脱凝集 / 分子シャペロン / 微小管結合蛋白 / 酸化ストレス / 微小管 / 電荷 / アクチン / 発生・分化 … More Except Principal Investigator 細胞行動 / 原生知能 / 行動力学 / ジオラマ環境 / 物理行動学 Less

細胞内のアクチン線維構造の修復を担う分子機構の解明Principal Investigator
- Principal Investigator
  
  篠原恭介
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Tokyo University of Agriculture and Technology
哺乳類の気道繊毛細胞がジオラマ環境変動に応答する際の原生知能の解明Principal Investigator
- Principal Investigator
  
  篠原恭介
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (IV)
- Research Institution
  Tokyo University of Agriculture and Technology
Ethological dynamics to formulate proto-intelligence exerted in diorama environments.
- Principal Investigator
  
  中垣俊之
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (IV)
- Research Institution
  Hokkaido University
Elucidation of a mechanism that protects lipid from oxidative stress in ciliated cellsPrincipal Investigator
- Principal Investigator
  
  Shinohara Kyosuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Tokyo University of Agriculture and Technology
細胞夾雑系における脱凝集因子Hsp104の特性解析と神経変性疾患治療への応用Principal Investigator
- Principal Investigator
  
  篠原恭介
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Tokyo University of Agriculture and Technology
Analysis of structure and function of actin bundle in the motile ciliated cellsPrincipal Investigator
- Principal Investigator
  
  Shinohara Kyosuke
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo University of Agriculture and Technology
Study on mechanism of rotational movement of node cilia in the mouse embryo by ultra high voltage electron microscopyPrincipal Investigator
- Principal Investigator
  
  SHINOHARA Kyosuke
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Developmental biology
- Research Institution
  Osaka University
磁気ピンセットによるマウス胚左右軸決定におけるノード流の作用機構の解明Principal Investigator
- Principal Investigator
  
  篠原恭介
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Developmental biology
- Research Institution
  Osaka University

All 2023 2022 2020 2018 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Rsph4a is essential for the triplet radial spoke head assembly of the mouse motile cilia2020
- Author(s)
  Yoke Hiroshi、Ueno Hironori、Narita Akihiro、Sakai Takafumi、Horiuchi Kahoru、Shingyoji Chikako、Hamada Hiroshi、Shinohara Kyosuke
- Journal Title
  
  PLOS Genetics
  
  Volume: 16 Issue: 3 Pages: e1008664-e1008664
- DOI
  10.1371/journal.pgen.1008664
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K12029, KAKENHI-PROJECT-17K17701
[Journal Article] Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm.2014
- Author(s)
  Dong, F., Shinohara, K., Nabeshima, R., Botilde, Y., Asai, Y., Fukumoto, A., Hasegawa, T., Matsuo, M., Takeda, H., Shiratori, H., Nakamura T., and Hamada, H.
- Journal Title
  
  J. Cell Biol.
  
  Volume: 204 Issue: 2 Pages: 203-213
- DOI
  10.1083/jcb.201304076
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-24113001, KAKENHI-PLANNED-24113004, KAKENHI-PROJECT-24770209, KAKENHI-PROJECT-25251029
[Journal Article] The dynamic right-to-left Translocation of Cerl2 is involved in the regulation and termination of nodal activity in the mouse node2013
- Author(s)
  Jose Manuel Ina cio, Sara Marques, Tetsuya Nakamura, Kyosuke Shinohara, Chikara Meno, Hiroshi Hamada, Jose Anto nio Belo
- Journal Title
  
  PLoS One
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24770209
[Journal Article] Asymmetric rotational stroke in mouse node cilia during left-right determination2013
- Author(s)
  A. Takamastu, T. Ishikawa, K. Shinohara, H. Hamada
- Journal Title
  
  Physical Review E
  
  Volume: 87 Issue: 5 Pages: 50701-50701
- DOI
  10.1103/physreve.87.050701
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24770209
[Journal Article] Cluap1 localizes preferentially to the base and tip of cilia and is required for ciliogenesis in the mouse embryo2013
- Author(s)
  Botilde, Y., Yoshiba, S., Shinohara, K., Hasegawa, T., Nishimura, H., Shiratori, H. and Hamada, H.
- Journal Title
  
  Developmental Biology
  
  Volume: 381 Issue: 1 Pages: 203-212
- DOI
  10.1016/j.ydbio.2013.05.024
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-24113001, KAKENHI-PLANNED-24113004, KAKENHI-PROJECT-24770209, KAKENHI-PROJECT-25251029
[Journal Article] Hydrodynamic phase locking in mouse node cilia2013
- Author(s)
  A. Takamastu, K. Shinohara, T. Ishikawa, H. Hamada
- Journal Title
  
  Physical Review Letters
  
  Volume: 110 Issue: 24 Pages: 248107-248107
- DOI
  10.1103/physrevlett.110.248107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24770209
[Journal Article] Two rotating cilia in the node cavity are sufficient to break left-right symmetry in the mouse embryo2012
- Author(s)
  Kyosuke Shinohara
- Journal Title
  
  Nature Commun.
  
  Volume: 3 Issue: 1 Pages: 622-622
- DOI
  10.1038/ncomms1624
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247034, KAKENHI-PROJECT-22770215, KAKENHI-PROJECT-23870018
[Journal Article] Fluid flow and interlinked feedback loops establish left-right asymmetric decay of Cerl2 mRNA in the mouse embryo2012
- Author(s)
  Nakamura, T., Saito, D., Kawasumi, A., Shinohara, K., Asai, Y., Takaoka, K., Dong, F., Takamatsu, A., Belo, J.A., Mochizuki, A., and Hamada, H.
- Journal Title
  
  Nat.Communic
  
  Volume: 3 Issue: 1 Pages: 1322-1322
- DOI
  10.1038/ncomms2319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247034, KAKENHI-PUBLICLY-22116508, KAKENHI-PROJECT-23657148, KAKENHI-PLANNED-24113004, KAKENHI-PROJECT-24687028, KAKENHI-PROJECT-24770209, KAKENHI-PLANNED-23119008, KAKENHI-ORGANIZER-24113001, KAKENHI-PUBLICLY-24116706
[Journal Article] Cilia at the Node of Mouse Embryos Sense Fluid Flow for Left-Right Determination via Pkd22012
- Author(s)
  Yoshiba S, Shiratori H, Kuo IY, Kawasumi A, Shinohara K, Nonaka S, Asai Y, Sasaki G, Belo JA, Sasaki H, Nakai J, Dworniczak B, Ehrlich BE, Pennekamp P, Hamada H
- Journal Title
  
  Science
  
  Volume: 338(6104):226-3 Issue: 6104 Pages: 226-231
- DOI
  10.1126/science.1222538
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22770215, KAKENHI-PLANNED-24113004, KAKENHI-PROJECT-24650214, KAKENHI-PROJECT-24770209, KAKENHI-ORGANIZER-24113001
[Presentation] マウス嗅上皮における微小管関連タンパク質Tppp3の機能解析2023
- Author(s)
  酒井敬史, 篠原恭介
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PLANNED-21H05307
[Presentation] マウス気管における微小管結合タンパク質Tppp3の細胞外部環境の制御における機能解析2023
- Author(s)
  渥美颯志郎, 篠原恭介
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PLANNED-21H05307
[Presentation] 原発性繊毛運動不全症の原因因子Dpcdのアクチン繊維構造に対する機能の解析2023
- Author(s)
  中山茉優, 篠原恭介
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PLANNED-21H05307
[Presentation] 原発性繊毛運動不全症の原因因子Dpcdの細胞内機能の解析2022
- Author(s)
  古池彩乃、篠原恭介
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PLANNED-21H05307
[Presentation] Primary Ciliary Dyskinesia protein Dpcd forms barrier that regulates transport between cilia and cytoplasm by electrostatic actin bundling2018
- Author(s)
  篠原恭介
- Organizer
  EMBO Workshop Cilia 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17701
[Presentation] Unexpectedly fragile architecture of nodal cilia that determine left-right asymmetry in the mouse embryo
- Author(s)
  Kyosuke Shinohara
- Organizer
  Cilia 2014
- Place of Presentation
  Paris, France
- Year and Date
  2014-11-18 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-24770209

1. 武田洋平 (30804447)

# of Collaborated Projects: 1 results

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2. 中垣俊之 (70300887)

# of Collaborated Projects: 1 results

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3. 石川拓司 (20313728)

# of Collaborated Projects: 1 results

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4. 紫加田知幸 (40603048)

# of Collaborated Projects: 1 results

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5. 柴小菊 (70533561)

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6. 菊地謙次 (00553801)

# of Collaborated Projects: 1 results

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7. 石本健太 (00741141)

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8. 飯間信 (90312412)

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9. 濱田博司

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# of Collaborated Products: 3 results
10. 上野裕則

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11. 白鳥秀卓

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# of Collaborated Products: 1 results

Shinohara Kyosuke 篠原 恭介

SHINOHARA Kyosuke 篠原 恭介

Research Projects

Research Products

Co-Researchers

細胞内のアクチン線維構造の修復を担う分子機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

哺乳類の気道繊毛細胞がジオラマ環境変動に応答する際の原生知能の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Ethological dynamics to formulate proto-intelligence exerted in diorama environments.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of a mechanism that protects lipid from oxidative stress in ciliated cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

細胞夾雑系における脱凝集因子Hsp104の特性解析と神経変性疾患治療への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of structure and function of actin bundle in the motile ciliated cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on mechanism of rotational movement of node cilia in the mouse embryo by ultra high voltage electron microscopyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

磁気ピンセットによるマウス胚左右軸決定におけるノード流の作用機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Rsph4a is essential for the triplet radial spoke head assembly of the mouse motile cilia2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The dynamic right-to-left Translocation of Cerl2 is involved in the regulation and termination of nodal activity in the mouse node2013

Author(s)

Journal Title

Data Source

[Journal Article] Asymmetric rotational stroke in mouse node cilia during left-right determination2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cluap1 localizes preferentially to the base and tip of cilia and is required for ciliogenesis in the mouse embryo2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hydrodynamic phase locking in mouse node cilia2013

Author(s)

Journal Title

Shinohara Kyosuke 篠原恭介

SHINOHARA Kyosuke 篠原恭介