IZAWA KIYOKO 伊澤清子

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Izawa Kiyoko 伊澤清子

IZAWA Kiyoko 伊澤清子

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Researcher Number	20534415
Affiliation (Current)	2025: 東京大学, 医科学研究所, 特任研究員
Affiliation (based on the past Project Information) *help	2024: 東京大学, 医科学研究所, 特任研究員 2023: 筑波大学, 附属病院, 研究員 2021 – 2022: 東京大学, 医科学研究所, 特任研究員 2013: 東京大学医科学研究所, 分子療法分野, 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Hematology
Keywords	Principal Investigator 好中球減少症 / 疾患特異的iPS / 造血幹細胞 / 好中球前駆細胞 / 造血幹前駆細胞 / ゲノム編集 / ヒト疾患特異的iPS細胞 / Wiskott-Aldrich Syndrom / 重症先天性好中球減少症 / 好中球分化 … More Except Principal Investigator … More Cre/loxP / レンチウイルス / MDS / 遺伝子変異 / 細胞初期化 / CD34陽性細胞 / 骨髄異形成症候群 / CD34+細胞 / センダイウイルスベクター / レンチウイルスベクター / 初期化因子 / 骨髄異形成症候群（MDS） / iPS細胞 Less

疾患特異的iPS細胞とバイオデータを用いた重症好中球減少症発症メカニズムの解明Principal Investigator
- Principal Investigator
  
  伊澤清子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  The University of Tokyo
Elucidation of Pathogenesis of Neutropenia Using iPS Cells and Genome Editing TechnologyPrincipal Investigator
- Principal Investigator
  
  Izawa Kiyoko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  University of Tsukuba
  The University of Tokyo
Establishment of a patient-derived iPS cells for simulating myelodysplastic syndrome
- Principal Investigator
  
  TOJO Arinobu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo

All 2022 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] A versatile drug delivery system using streptavidin-tagged pegylated liposomes and biotinylated biomaterials2013
- Author(s)
  Chen MH, Soda Y, Izawa K, Kobayashi S, Tani K, Maruyama K, Tojo A, Asano S
- Journal Title
  
  Int J Pharm
  
  Volume: 454(1) Pages: 478-85
- Data Source
  KAKENHI-PROJECT-23591373
[Journal Article] In vivo leukemogenic potential of an interleukin-7 receptor-a mutant in hematopoietic stem/progenitor cells2013
- Author(s)
  Yokoyama K, Yokoyama N, Izawa K, Kotani A, Harashima A, Hozumi K, Tojo A
- Journal Title
  
  Blood
  
  Volume: 22(26) Pages: 4259-63
- Data Source
  KAKENHI-PROJECT-23591373
[Journal Article] Bioimaging analysis of NF-kB activity in Ph-positive acute lymphoblastic leukemia cells unveils its synergistic up-regulation by TNFa-stimulated changes to the microenvironment2011
- Author(s)
  Tsai HJ, Kobayashi S, Izawa K, Ishida T, Watanabe T, Umezawa K, Lin SF, Tojo A
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Pages: 2014-21
- Data Source
  KAKENHI-PROJECT-23591373
[Journal Article] Gaussia luciferase for bioluminescence tumor monitoring in comparison with firefly luciferase.2011
- Author(s)
  Inoue Y, Sheng F, Kiryu S, Watanabe M, Harnprasopwat R, Izawa K, Tojo A, Ohtomo K.
- Journal Title
  
  Molecular Imaging.
  
  Volume: 10 Issue: 5 Pages: 377-385
- DOI
  10.2310/7290.2010.00057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591373
[Journal Article] Bioimaging analysis of NF-κB activity in Ph-positive acute lymphoblastic leukemia cells unveils its synergistic up-regulation by TNFα-stimulated changes to the microenvironment.2011
- Author(s)
  Tsai HJ, Kobayashi S, Izawa K, Ishida T, Watanabe T, Umezawa K, Lin SF, Tojo A.
- Journal Title
  
  Cancer Science
  
  Volume: 102 Issue: 11 Pages: 2014-2021
- DOI
  10.1111/j.1349-7006.2011.02039.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591373
[Journal Article] Gaussia luciferase for bioluminescence tumor monitoring in comparison with firefly luciferase2011
- Author(s)
  Inoue Y, Sheng F, Kiryu S, Watanabe M, Harnprasopwat R, Izawa K, Tojo A, Ohtomo K
- Journal Title
  
  Mol Imaging
  
  Volume: 10 Pages: 377-85
- Data Source
  KAKENHI-PROJECT-23591373
[Presentation] A novel neutrophil development model using human Severe Congenital Neutropenia-iPS-derived HSPCs2022
- Author(s)
  Kiyoko Izawa, Satoshi Yamazaki, Hijiri Saito, Hans Jiro Becker, Momoko Sakaguchi, Arinobu Tojo
- Organizer
  日本血液学会
- Data Source
  KAKENHI-PROJECT-21K07745
[Presentation] Long-term ex vivo maintenance of murine iPSC-derived hematopoietic stem/progenitor cells by conditional HoxB42013
- Author(s)
  Izawa K, Yamamoto M, Tojo A
- Organizer
  The 55th American Society of Hematology Annual Meeting and Exposition
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23591373
[Presentation] Impairment of T cell development in chronic myeloid leukemia, partial explanation by in vitro model.2012
- Author(s)
  1. Chanda Bidisha、伊澤清子、Harnprasopwat Ratanakanit、小林誠一郎、東條有伸.
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23591373
[Presentation] Bcr-Abl impairs T cell development from murine induced pluripotent stem cells and hematopoietic stem cells; a partial explanation for the concept that Ph+ clone never involves T cell lineage in CML.2011
- Author(s)
  Bidisha C, Izawa K, Harnprasopwat R, Takahashi K, Kobayashi S, Kanegae Y, Saito I, Tojo A.
- Organizer
  53rd ASH (American Society of Hematology) Annual Meeting and Exposition.
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-23591373
[Presentation] The in vitro and in vivo oncogenic activity of homodimeric mutant of interleukin-7 receptor a chain (IL7Rα) highlights the significance of the IL7Rα/Jak1 pathway in T-cell acute lymphoblastic leukemia2011
- Author(s)
  Yokoyama K, Yokoyama N, Izawa K, Kotani A, Harnprasopwat R, Harashima A, Kobayashi S, Tojo A
- Organizer
  53rd American Society of Hematology (ASH) Annual Meeting and Exposition
- Place of Presentation
  San Diego, USA(Oral Presentation)
- Year and Date
  2011-12-11
- Data Source
  KAKENHI-PROJECT-23591373
[Presentation] Bcr-Abl impairs T cell development from murine induced pluripotent stem cells; a possible explanation for T cell escape from leukemic clone in chronic myeloid leukemia2011
- Author(s)
  Bidisha C, Izawa K, Harnprasopwat R, Takahashi K, Kobayashi S, Kanegae Y, Saito I, Tojo A
- Organizer
  9th ISSCR (International Society for Stem Cell Research) Annual Meeting
- Place of Presentation
  Toronto, Canada(Poster Presentation)
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-23591373
[Presentation] Bcr-Abl impairs T cell development from murine induced pluripotent stem cells and hematopoietic stem cells; a partial explanation for the concept that Ph+ clone never involves T cell lineage in CML2011
- Author(s)
  Bidisha C, Izawa K, Harnprasopwat R, Takahashi K, Kobayashi S, Kanegae Y, Saito I, Tojo A
- Organizer
  53rd ASH (American Society of Hematology) Annual Meeting and Exposition
- Place of Presentation
  San Diego, USA(Poster Presentation)
- Year and Date
  2011-12-12
- Data Source
  KAKENHI-PROJECT-23591373
[Presentation] Long-term ex vivo maintenance of murine iPSC-derived hematopoietic stem/progenitor cells by conditional HoxB4. The 55th American Society of Hematology Annual Meeting and Exposition.
- Author(s)
  Izawa K, Yamamoto M, Tojo A.
- Organizer
  The 55th American Society of Hematology Annual Meeting and Exposition.
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23591373

1. TOJO Arinobu (00211681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
2. KOBAYASHI Seiichiro (70376622)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results

IZAWA KIYOKO 伊澤 清子

Izawa Kiyoko 伊澤 清子

IZAWA Kiyoko 伊澤 清子

Research Projects

Research Products

Co-Researchers

疾患特異的iPS細胞とバイオデータを用いた重症好中球減少症発症メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of Pathogenesis of Neutropenia Using iPS Cells and Genome Editing TechnologyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of a patient-derived iPS cells for simulating myelodysplastic syndrome

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A versatile drug delivery system using streptavidin-tagged pegylated liposomes and biotinylated biomaterials2013

Author(s)

Journal Title

Data Source

[Journal Article] In vivo leukemogenic potential of an interleukin-7 receptor-a mutant in hematopoietic stem/progenitor cells2013

Author(s)

Journal Title

Data Source

[Journal Article] Bioimaging analysis of NF-kB activity in Ph-positive acute lymphoblastic leukemia cells unveils its synergistic up-regulation by TNFa-stimulated changes to the microenvironment2011

Author(s)

Journal Title

Data Source

[Journal Article] Gaussia luciferase for bioluminescence tumor monitoring in comparison with firefly luciferase.2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Bioimaging analysis of NF-κB activity in Ph-positive acute lymphoblastic leukemia cells unveils its synergistic up-regulation by TNFα-stimulated changes to the microenvironment.2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gaussia luciferase for bioluminescence tumor monitoring in comparison with firefly luciferase2011

Author(s)

Journal Title

Data Source

[Presentation] A novel neutrophil development model using human Severe Congenital Neutropenia-iPS-derived HSPCs2022

Author(s)

Organizer

Data Source

[Presentation] Long-term ex vivo maintenance of murine iPSC-derived hematopoietic stem/progenitor cells by conditional HoxB42013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Impairment of T cell development in chronic myeloid leukemia, partial explanation by in vitro model.2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Bcr-Abl impairs T cell development from murine induced pluripotent stem cells and hematopoietic stem cells; a partial explanation for the concept that Ph+ clone never involves T cell lineage in CML.2011

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] The in vitro and in vivo oncogenic activity of homodimeric mutant of interleukin-7 receptor a chain (IL7Rα) highlights the significance of the IL7Rα/Jak1 pathway in T-cell acute lymphoblastic leukemia2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Bcr-Abl impairs T cell development from murine induced pluripotent stem cells; a possible explanation for T cell escape from leukemic clone in chronic myeloid leukemia2011

Author(s)

Organizer

Place of Presentation

Year and Date

IZAWA KIYOKO 伊澤清子

Izawa Kiyoko 伊澤清子

IZAWA Kiyoko 伊澤清子