takeuchi toshiyuki 竹内俊幸

… Alternative Names

俊幸トシユキ

竹内俊幸タケウチトシユキ

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Researcher Number	20538483
Other IDs
Affiliation (Current)	2025: 藤田医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2018 – 2024: 藤田医科大学, 医学部, 助教
Review Section/Research Field	Except Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 53030:Respiratory medicine-related
Keywords	Except Principal Investigator がん幹細胞 / PDX / ゲノム不安定化 / 複製ストレス / POLD4 / 肺がん / 転写因子 / アクチン / 細胞骨格 / 創薬 … More / スフィンゴ脂質 / 細胞遊走 / セラミド / 転移 / CERS6 / 肺癌 Less

Analysis of lineage-specific cancer stem cell markers using lung cancer PDX models
- Principal Investigator
  
  水谷泰嘉
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Fujita Health University
Fork Reversal因子POLD4を指標とした新規肺癌分子標的治療法の開発
- Principal Investigator
  
  新美敦子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Fujita Health University
Targeting ceramide synthase 6–dependent metastasis-prone phenotype in lung cancer cells
- Principal Investigator
  
  Suzuki Motoshi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Fujita Health University

All 2023 2022 2021 2020 2019 2018

All Journal Article Presentation Patent

[Journal Article] LASP1, CERS6, and Actin Form a Ternary Complex That Promotes Cancer Cell Migration2023
- Author(s)
  Niimi Atsuko、Limsirichaikul Siripan、Kano Keiko、Mizutani Yasuyoshi、Takeuchi Toshiyuki、Sawangsri Patinya、Tran Dat Quoc、Kawamoto Yoshiyuki、Suzuki Motoshi
- Journal Title
  
  Cancers
  
  Volume: 15 Issue: 10 Pages: 2781-2781
- DOI
  10.3390/cancers15102781
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08217, KAKENHI-PROJECT-22K07263
[Journal Article] CEBPγ facilitates lamellipodia formation and cancer cell migration through CERS6 upregulation2021
- Author(s)
  Hanxiao Sh, Atsuko Niimi, Toshiyuki Takeuchi, Kazuya Shiogama, Yasuyoshi Mizutani, Taisuke Kajino, Kenichi Inada, Tetsunari Hase, Takahiro Hatta, Hirofumi Shibata, Takayuki Fukui, Toyofumi Fengshi Chen-Yoshikawa, Kazuki Nagano, Takashi Murate, Yoshiyuki Kawamoto, Shuta Tomida, Takashi Takahashi, Motoshi Suzuki
- Journal Title
  
  Cancer Science
  
  Volume: 未定 Issue: 7 Pages: 2770-2780
- DOI
  10.1111/cas.14928
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07030, KAKENHI-PROJECT-18K07193, KAKENHI-PROJECT-16H02468, KAKENHI-PROJECT-18H02698, KAKENHI-PROJECT-20H03771
[Journal Article] CEBPgamma facilitates lamellipodia formation and cancer cell migration through CERS6 upregulation2021
- Author(s)
  Shi H, Niimi A, Takeuchi T, Shiogama K, Mizutani Y, Kajino T, Inada K, Hase T, Hatta T, Shibata H, Fukui T, Chen-Yoshikawa T-F, Nagano K, Murate T, Kawamoto Y, Tomida S, Takahashi T, Suzuki, M
- Journal Title
  
  Cancer Science
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02698
[Journal Article] CERS6 required for cell migration and metastasis in lung cancer.2020
- Author(s)
  Suzuki M, Cao K, Kato S, Mizutani N, Tanaka K, Arima C, Tai MC, Nakatani N, Yanagisawa K, Takeuchi T, Shi H, Mizutani Y, Niimi A, Taniguchi T, Fukui T, Yokoi K, Wakahara K, Hasegawa Y, Mizutani Y, Iwaki S, Fujii S, Satou A, Tamiya-Koizumi K, Murate T, Kyogashima M, Tomida S, Takahashi T.
- Journal Title
  
  J Cell Mol Med.
  
  Volume: 24 Issue: 20 Pages: 11949-11959
- DOI
  10.1111/jcmm.15817
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02468, KAKENHI-PROJECT-18H02698, KAKENHI-PROJECT-20H03771, KAKENHI-PROJECT-18K08174
[Patent] がん転移抑制剤2019
- Inventor(s)
  鈴木元、竹内俊幸、高橋隆、磯村久徳、小泉惠子、安藤隆幸
- Industrial Property Rights Holder
  学校法人藤田学園
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18H02698
[Presentation] YBX1 is a tuner to suppress PD-L1 expression in lung cancer2023
- Author(s)
  Yasuyoshi Mizutani, Toshiyuki Takeuchi, Atsuko Niimi, Siripan Limsirichaikul, Patinya Sawangsri, Tran Quoc Dat, Ken-ichi Inada, Tetsuya Tsukamoto, Masashi Kondo, Motoshi Suzuki
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K07263
[Presentation] SMARCA4 and SMARCAD1 confer pathways that suppress DNA replication stress in non-small cell lung cancer2023
- Author(s)
  Patinya Sawangsri, Atsuko Niimi, Siripan Limsirichaikul, Dat Quoc Tran, Yasuyoshi Mizutani, Toshiyuki Takeuchi, Motoshi Suzuki
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K07263
[Presentation] POLD4-PRIMPOL経路を標的とした新規非小細胞肺がん治療法の検討2023
- Author(s)
  新美敦子、Siripan Limsirichaikul、Patinya Sawangsri、Dat Quoc Tran、水谷泰嘉、竹内俊幸、鈴木元
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K07263
[Presentation] Targeting the POLD4-PRIMPOL pathway in non-small cell lung cancer2023
- Author(s)
  Atsuko Niimi, Siripan Limsirichaikul, Patinya Sawangsri, Tran Quoc Dat, Yasuyoshi Mizutani, Toshiyuki Takeuchi, Motoshi Suzuki
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K07263
[Presentation] CERS6-LASP1-actin coordinated to facilitate lung cancer cell migration Alternative title; LASP1, CERS6, and actin form ternary complex that promotes cancer cell migration2023
- Author(s)
  Siripan Limsirichaikul, Atsuko Niimi, Yasuyoshi Mizutani, Toshiyuki Takeuchi, Patinya Sawangsri, Tran Quoc Dat, Motoshi Suzuki
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K07263
[Presentation] LASP1 tethers CERS6 at lamellipodia and promotes cancer cell migration2022
- Author(s)
  Siripan Limsirichaikul, Atsuko Niimi, Toshiyuki Takeuchi, Yasuyoshi Mizutani, Patinya Sawangsri, Tran Quoc Dat, Motoshi Suzuki
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K07263
[Presentation] Functional analysis of YBX1 in PD-L1 expression in lung cancer2022
- Author(s)
  Yasuyoshi Mziutani, Toshiyuki Takeuchi, Atsuko Niimi, Siripan Limsirichaikul, Patinya Sawangsri, Tran Quoc Dat, Ken-ichi Inada, Motoshi Suzuki
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K07263
[Presentation] POLD4-dependent DDR pathway may be targeted in non-small cell lung cancer2022
- Author(s)
  Atsuko Niimi, Siripan Limsirichaikul, Patinya Sawangsri, Tran Quoc Dat, Yasuyoshi Mizutani, Toshiyuki Takeuchi, Motoshi Suzuki
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K07263
[Presentation] CERS6 and CEBPg required for cell migration and metastasis through an alteration in the ceramide metabolic profile.2021
- Author(s)
  Hanxiao Shi, Toshiyuki Takeuchi, Atsuko Niimi, Yasuyoshi Mizutani, Taisuke Kajino, Shuta Tomida, Takashi Takahashi, Motoshi Suzuki
- Organizer
  第80回日本癌学会
- Data Source
  KAKENHI-PROJECT-18H02698
[Presentation] POLD4 pathway is required for repair of CDDP-induced DNA damage.2021
- Author(s)
  Atsuko Niimi, Yasuyoshi Mizutani, Toshiyuki Takeuchi, Motoshi Suzuki
- Organizer
  第80回日本癌学会
- Data Source
  KAKENHI-PROJECT-18H02698
[Presentation] A suppressor role of POLD4, the smallest subunit of DNA polymerase d complex, in lung cancer2020
- Author(s)
  Atsuko Niimi, Yasuyoshi Mizutani, Toshiyuki Takeuchi, Motoshi Suzuki
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-18H02698
[Presentation] 病変組織内の特異的抗体産生細胞を可視化する「酵素抗原法」の技術開発2019
- Author(s)
  水谷泰嘉、塩竈和也、竹内俊幸、新美敦子、石含笑、稲田健一、鈴木元
- Organizer
  第60回日本組織細胞化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18H02698
[Presentation] DNAポリメラーゼδ複合体サブユニットPOLD4の肺がん発生における役割解析2019
- Author(s)
  新美敦子、岩瀬咲良、竹内俊幸、水谷泰嘉、鈴木元
- Organizer
  第42回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-18H02698
[Presentation] A metastasis protein CERS6 is transcriptionally regulated by miR-101 and YB-1.2018
- Author(s)
  Hanxiao Shi, Toshiyuki Takeuchi, Atsuko Niimi, Yasuyoshi Mizutani, Takashi Murate, Takashi Suzuki, Motoshi Suzuki
- Organizer
  第76回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-18H02698

1. Suzuki Motoshi (80236017)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
2. 水谷泰嘉 (10546229)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
3. 新美敦子 (50508984)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
4. 安藤隆幸 (40402226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 村手隆 (30239537)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 塚本徹哉 (00236861)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SHIOGAMA Kazuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 稲田健一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 高橋隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

takeuchi toshiyuki 竹内 俊幸

俊幸 トシユキ

竹内 俊幸 タケウチ トシユキ

Research Projects

Research Products

Co-Researchers

Analysis of lineage-specific cancer stem cell markers using lung cancer PDX models

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Fork Reversal因子POLD4を指標とした新規肺癌分子標的治療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Targeting ceramide synthase 6&#8211;dependent metastasis-prone phenotype in lung cancer cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] LASP1, CERS6, and Actin Form a Ternary Complex That Promotes Cancer Cell Migration2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CEBPγ facilitates lamellipodia formation and cancer cell migration through CERS6 upregulation2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CEBPgamma facilitates lamellipodia formation and cancer cell migration through CERS6 upregulation2021

Author(s)

Journal Title

Data Source

[Journal Article] CERS6 required for cell migration and metastasis in lung cancer.2020

Author(s)

Journal Title

DOI

Data Source

[Patent] がん転移抑制剤2019

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] YBX1 is a tuner to suppress PD-L1 expression in lung cancer2023

Author(s)

Organizer

Data Source

[Presentation] SMARCA4 and SMARCAD1 confer pathways that suppress DNA replication stress in non-small cell lung cancer2023

Author(s)

Organizer

Data Source

[Presentation] POLD4-PRIMPOL経路を標的とした新規非小細胞肺がん治療法の検討2023

Author(s)

Organizer

Data Source

[Presentation] Targeting the POLD4-PRIMPOL pathway in non-small cell lung cancer2023

Author(s)

Organizer

Data Source

[Presentation] CERS6-LASP1-actin coordinated to facilitate lung cancer cell migration Alternative title; LASP1, CERS6, and actin form ternary complex that promotes cancer cell migration2023

Author(s)

Organizer

Data Source

[Presentation] LASP1 tethers CERS6 at lamellipodia and promotes cancer cell migration2022

Author(s)

Organizer

Data Source

[Presentation] Functional analysis of YBX1 in PD-L1 expression in lung cancer2022

Author(s)

Organizer

Data Source

[Presentation] POLD4-dependent DDR pathway may be targeted in non-small cell lung cancer2022

Author(s)

Organizer

takeuchi toshiyuki 竹内俊幸

俊幸トシユキ

竹内俊幸タケウチトシユキ

Targeting ceramide synthase 6–dependent metastasis-prone phenotype in lung cancer cells