Niwa Akira 丹羽明

… Alternative Names

丹羽明ニワアキラ

NIWA Akira 丹羽明

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Researcher Number	20546999
Other IDs
Affiliation (Current)	2025: 京都大学, iPS細胞研究所, 特定拠点助教
Affiliation (based on the past Project Information) *help	2020 – 2022: 京都大学, iPS細胞研究所, 特定拠点助教 2016 – 2018: 京都大学, iPS細胞研究所, 特定拠点助教 2016: 京都大学, 医学系研究科, 助教 2012 – 2015: 京都大学, iPS細胞研究所, 助教 2013: 京都大学, ips細胞研究所, 助教 2012: 京都大学, iPS 細胞研究所, 特定助教 2010 – 2011: 京都大学, iPS細胞研究所, 特定研究員
Review Section/Research Field	Principal Investigator Pediatrics Except Principal Investigator Pediatrics / Basic Section 52010:General internal medicine-related / Neurosurgery
Keywords	Principal Investigator iPS細胞 / 白血病 / 造血発生 / 発現制御 / シグナル伝達 / 遺伝子 / 癌 / クローン進化 / 白血病モデル / 疾患モデル … More / 順遺伝学 / ＥＳ／ｉＰＳ細胞 / 造血幹細胞 / 造血分化 / ヒトiPS細胞 / ヒトES細胞 / 造血細胞分化 / ヒトES/iPS細胞 / ES/iPS細胞 / 再生医学 / 無血清培養 / 中胚葉分化 … More Except Principal Investigator ニッチ / ストロマ細胞 / 造血幹細胞 / iPS細胞 / 脂質因子 / 赤芽球 / アディポネクチン / CPT-1α / 亜鉛 / エリスロポエチン抵抗性 / 腎性貧血 / 網赤血球数 / 血清脂質 / 脂肪酸β酸化 / アシルカルニチン / 血液透析患者 / エリスロポエチン / 腎性腎血 / 癌抑制遺伝子 / 腫瘍血管新生 / VHL病 / 血管芽腫 / ES／iPS細胞 / 細胞内代謝 / 臨床応用 / 移植・再生医療 / ES/iPS細胞 / ES細胞 / 創薬 / 疾患特異的 / NOGマウス / 疾患解析 / 遺伝子改変 / 遺伝性疾患 Less

Investigation of new erythropoietin resistance factors and the mechanisms: with special attentions to associations between erythropoiesis and lipid metabolism
- Principal Investigator
  
  Kimura Hideki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  University of Fukui
Study on the clonal evolution of leukemia induced with internal mutatorsPrincipal Investigator
- Principal Investigator
  
  Niwa Akira
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto University
Induction and expansion of PSC-derived HSCs by manipulating culture microenvironment
- Principal Investigator
  
  Nakahata Tatsutoshi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto University
Identification of causative genes for hemangioblastoma to elucidate the mechanisms of neovascularization and to develop novel therapeutic strategies
- Principal Investigator
  
  Mukasa Akitake
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurosurgery
- Research Institution
  The University of Tokyo
Phenomic Screen to Explore Novel Pathogenesis of Leukemia Using PSC-Derived Hematopoietic CellsPrincipal Investigator
- Principal Investigator
  
  NIWA Akira
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto University
Hematopoietic stem cell potential is propagated by human pluripotent stem cell-derived endothelial stroma
- Principal Investigator
  
  NAKAHATA Tatsutoshi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto University
Recapitulation of phenotypes and discovery of a novel treatment with disease-specific human ES/ iPS cells from various hereditary diseases
- Principal Investigator
  
  NAKAHATA Tatsutoshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto University
Induction of hematopoietic stem/progenitor cells and functional blood cells from human ES/iPS cellsPrincipal Investigator
- Principal Investigator
  
  NIWA Akira
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kyoto University

All 2018 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book Patent

[Book] 幹細胞の体外増幅法の現状と将来医学のあゆみ2012
- Author(s)
  丹羽明、中畑龍俊
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-22790979
[Book] iPS細胞からの造血分化Annual Review血液2009
- Author(s)
  丹羽明, 中畑龍俊
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-22790979
[Book] 疾患由来iPS細胞の樹立分子細胞治療2009
- Author(s)
  丹羽明, 中畑龍俊
- Publisher
  メテオMBC
- Data Source
  KAKENHI-PROJECT-22790979
[Book] ES, iPS細胞からの機能的赤血球産生血液フロンティア2009
- Author(s)
  丹羽明
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-22790979
[Journal Article] Specific Antileukemic Activity of PD0332991, a CDK4/6 Inhibitor, against Philadelphia Chromosome-Positive Lymphoid Leukemia.2016
- Author(s)
  Nemoto A, Saida S, Kato I, Kikuchi J, Furukawa Y, Maeda Y, Akahane K, Honna-Oshiro H, Goi K, Kagami K, Kimura S, Sato Y, Okabe S, Niwa A, Watanabe K, Nakahata T, Heike T, Sugita K, Inukai T.
- Journal Title
  
  Mol Cancer Ther.
  
  Volume: 15 Issue: 1 Pages: 94-105
- DOI
  10.1158/1535-7163.mct-14-1065
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09645, KAKENHI-PROJECT-26670498, KAKENHI-PROJECT-26461430
[Journal Article] Pluripotent cell models of Fanconi anemia identify the early pathological defect in human hemoangiogenic progenitors.2015
- Author(s)
  Suzuki NM, Niwa A, Yabe M, Hira A, Okada C, Amano N, Watanabe A, Watanabe K, Heike T, Takata M, Nakahata T, Saito MK
- Journal Title
  
  Stem Cells Transl Med
  
  Volume: 4 Issue: 4 Pages: 333-338
- DOI
  10.5966/sctm.2013-0172
- NAID
  120005980869
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461591, KAKENHI-PROJECT-26670498, KAKENHI-PROJECT-15K06921, KAKENHI-PLANNED-23114010, KAKENHI-PROJECT-15H01738, KAKENHI-PROJECT-26550026
[Journal Article] HAX1 in induced pluripotent stem cells from a patient with severe congenital neutropenia improves defective granulopoiesis.2014
- Author(s)
  Morishima T, Watanabe K, Niwa A, Hirai H, Saida S, Tanaka T, Kato I, Umeda K, Hiramatsu H, Saito MK, Matsubara K, Adachi S, Kobayashi M, Nakahata T, Heike T
- Journal Title
  
  Haematologica
  
  Volume: 99(1) Issue: 1 Pages: 19-27
- DOI
  10.3324/haematol.2013.083873
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390244, KAKENHI-PROJECT-24591548, KAKENHI-PROJECT-24659461, KAKENHI-PROJECT-24659496, KAKENHI-PROJECT-25293231, KAKENHI-PROJECT-25430149, KAKENHI-PROJECT-25461415, KAKENHI-PROJECT-25461591, KAKENHI-PROJECT-26670498, KAKENHI-PROJECT-26670501
[Journal Article] Genetic correction of HAX1 in induced pluripotent stem cells from a patient with severe congenital neutropenia improves defective granulopoiesis2014
- Author(s)
  Morishima T., Watanabe K., Niwa A., Hirai H., Saida S., Tanaka T., Kato I., Umeda K., Hiramatsu H., Saito M. K., Matsubara K., Adachi S., Kobayashi M., Nakahata T., Heike T.
- Journal Title
  
  Haematologica
  
  Volume: 99(1) Pages: 19-27
- Data Source
  KAKENHI-PROJECT-24659496
[Journal Article] Robust and highly-efficient differentiation of functional monocytic cells from human pluripotent stem cells under serum- and feeder cell- free conditions.2013
- Author(s)
  Yanagimachi MD, Niwa A, Tanaka T, Ozaki F, Nishimoto S, Murata Y, Yasumi T, Ito J, Tomida S, Oshima K, Asaka I, Goto H, Heike T, Nakahata T, Saito MK
- Journal Title
  
  PLoS ONE
  
  Volume: 8(4) Issue: 4 Pages: e59243-e59243
- DOI
  10.1371/journal.pone.0059243
- NAID
  120005244458
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249042, KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-22591159, KAKENHI-PROJECT-23657147, KAKENHI-PROJECT-24659496, KAKENHI-PROJECT-24790997, KAKENHI-PROJECT-25461591
[Journal Article] 幹細胞増幅2012
- Author(s)
  中畑龍俊、丹羽明
- Journal Title
  
  カラー版内科学
  
  Volume: 総編集
- Data Source
  KAKENHI-PROJECT-24659496
[Journal Article] Induced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discovery2012
- Author(s)
  Tanaka T., Takahashi K., Yamane M., Tomida S., Nakamura S., Oshima K., Niwa A., Nishikomori R., Kambe N., Hara H., Mitsuyama M., Morone N., Heuse J.E., Yamamoto T., Watanabe A., Sato-Otsubo A., Ozawa S., Asaka I., Heike T., Yamanaka S., Nak
- Journal Title
  
  Blood
  
  Volume: 120(6) Issue: 6 Pages: 1299-308
- DOI
  10.1182/blood-2012-03-417881
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249042, KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-22790283, KAKENHI-PROJECT-23310087, KAKENHI-PROJECT-23390280, KAKENHI-PROJECT-23657147, KAKENHI-PROJECT-24390263, KAKENHI-PROJECT-24590524, KAKENHI-PROJECT-24659496
[Journal Article] Induced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discovery.2012
- Author(s)
  Tanaka T., Oshima K., Niwa A., Nishikomori R., Kambe N., Hara H., Mitsuyama M., Ozawa S., Asaka I., Heike T., Yamanaka S., Nakahata T., Saito M.K. 他７名１５番目
- Journal Title
  
  Blood
  
  Volume: 120 Pages: 1299-1308
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659496
[Journal Article] 幹細胞増幅、第10章内科疾患と再生医療2012
- Author(s)
  中畑龍俊、丹羽明
- Journal Title
  
  カラー版内科学、門脇孝、永井良三(総編集)
  
  Pages: 447-450
- Data Source
  KAKENHI-PROJECT-24659496
[Journal Article] Selective development of myogenic mesenchymal cells from human embryonic and induced pluripotent stem cells2012
- Author(s)
  Awaya T., Kato T., Mizuno Y., Chang H., Niwa A., Umeda K., Nakahata T., Heike T.
- Journal Title
  
  PLoS ONE
  
  Volume: 7(12) Issue: 12 Pages: e51638-e51638
- DOI
  10.1371/journal.pone.0051638
- NAID
  120005122354
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249042, KAKENHI-PROJECT-23659520, KAKENHI-PROJECT-23791170, KAKENHI-PROJECT-24591507, KAKENHI-PROJECT-24591508
[Journal Article] Induced pluripotent stem cells from CINCAsyndrome patients as a model for dissecting somatic mosaicism and drugdiscovery2012
- Author(s)
  Tanaka T, Takahashi K, Yamane M, Tomida S, Nakamura S, Oshima K, Niwa A, Nishikomori R, Kambe N, Hara H, Mitsuyama M, Morone N, Heuser JE, Yamamoto T, Watanabe A, Sato-Otsubo A, Ozawa S, AsakaI, Heike T, Yamanaka S, Nakahata T, and Saito MK
- Journal Title
  
  Blood
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790979
[Journal Article] A novel serum-free monolayer culture for orderly hematopoietic differentiation of human pluripotentcells via mesodermal progenitors2011
- Author(s)
  Niwa A, Heike T, Umeda K, Oshima K, KatoI, Sakai H, Suemori H, Nakahata T, Saito MK
- Journal Title
  
  PLoS One
  
  Volume: 6(7)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790979
[Journal Article] Identification of Hepatic Niche Harboring Human Acute Lymphoblastic Leukemic Cells via the SDF-1/CXCR4 Axis2011
- Author(s)
  Kato I, Niwa A, Heike T, Fujino H, Saito MK, Umeda K., Hiramatsu H., Ito M., Morita M., Nishinaka Y., Adachi S., Ishikawa F., Nakahata T.
- Journal Title
  
  PLoS ONE
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249042
[Journal Article] A novel serum-free monolayer culture for orderly hematopoietic differentiation of human pluripotent cells via mesodermal progenitors2011
- Author(s)
  Niwa A, Heike T, Umeda K, et al.
- Journal Title
  
  PloS One
  
  Volume: 6 Issue: 7 Pages: e22261-e22261
- DOI
  10.1371/journal.pone.0022261
- NAID
  120003324603
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591360, KAKENHI-PROJECT-22249042, KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-22790979, KAKENHI-PROJECT-23591561, KAKENHI-PROJECT-23657147
[Journal Article] Neutrophil differentiation from human-induced pluripotent stem cells2011
- Author(s)
  Morishima T, Watanabe K, Niwa A, et al.
- Journal Title
  
  J CellPhysiol
  
  Volume: 226(5) Issue: 5 Pages: 1283-91
- DOI
  10.1002/jcp.22456
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591360, KAKENHI-PROJECT-22249042
[Journal Article] Neutrophil differentiation from human-induced pluripotent stem cells2011
- Author(s)
  Morishima T, Watanabe K, Niwa A, Fujino H, Matsubara H, Adachi S, Suemori H, Nakahata T, Heike T
- Journal Title
  
  J Cell Physiol
  
  Volume: 226(5) Pages: 1283-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790979
[Journal Article] A novel serum-free monolayer culture for orderly hematopoietic differentiation of human pluripotent cells via mesodermal progenitors2011
- Author(s)
  Niwa A., Heike T., Umeda K., Oshima K., Kato I., Sakai H., Suemori H., Nakahata T., Saito M.
- Journal Title
  
  PLoS ONE
  
  Volume: 6
- NAID
  120003324603
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249042
[Journal Article] Generation of skeletal muscle stem/progenitor cells from murine induced pluripotent stem cells2010
- Author(s)
  Mizuno Y., Chang H., Umeda K., Niwa A., Iwasa T., Awaya T., Fukada S., Hiroshi Yamamoto H., Yamanaka S., Nakahata T., Heike T.
- Journal Title
  
  FASEB J
  
  Volume: 24 Issue: 7 Pages: 2245-2253
- DOI
  10.1096/fj.09-137174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249042
[Patent] 多能性幹細胞から樹状細胞への分化誘導法2011
- Inventor(s)
  中畑龍俊/斎藤潤/丹羽明/柳町昌克
- Industrial Property Rights Holder
  京都大学
- Filing Date
  2011-02-23
- Overseas
- Data Source
  KAKENHI-PROJECT-22249042
[Presentation] iPSC-Based Phenomic Screen Revealed an Impact of Uncontrolled NFkB Activity at the Initiating Stages of AML1-ETO Related Leukemia2018
- Author(s)
  丹羽明
- Organizer
  米国血液学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10026
[Presentation] The cooperation between gene alterations and cell lineages in leukemogenesis2016
- Author(s)
  丹羽明
- Organizer
  日本血液学会
- Place of Presentation
  横浜パシフィコ
- Data Source
  KAKENHI-PROJECT-16K10026
[Presentation] PSC-Derived Hematopoietic System to Elucidate the Cooperation Between Gene Alterations and Cell Lineages in Leukemogenesis2016
- Author(s)
  丹羽明
- Organizer
  米国血液学会
- Place of Presentation
  米国サンディエゴ
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10026
[Presentation] Exploring the pathogenesis of transient my-exploliferative disorder using iPSCs.2015
- Author(s)
  Nishinaka Yoko, Niwa Akira, Osawa Mitsujiro, Nakahata Tatsutoshi, Saito Megumu K.
- Organizer
  ISSCR 2015 Annual Meeting
- Place of Presentation
  Stockholmsmässan Exhibition and Convention Center(Sweden)
- Year and Date
  2015-06-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670498
[Presentation] PSC-Derived hematopoietic cells as a new tool for exploring leukemia pathogenesis.2015
- Author(s)
  Niwa Akira, Saito Megumu, Nakahata Tatsutoshi
- Organizer
  ISSCR 2015 Annual Meeting
- Place of Presentation
  Stockholmsmässan Exhibition and Convention Center(Sweden)
- Year and Date
  2015-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670498
[Presentation] Sequential switching of matrices directs human pluripotent stem cells into endothelial lineage.2015
- Author(s)
  Ohta Ryo, Niwa Akira, Nakahata Tatsutoshi, Saito Megumu
- Organizer
  ISSCR 2015 Annual Meeting
- Place of Presentation
  Stockholmsmässan Exhibition and Convention Center(Sweden)
- Year and Date
  2015-06-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670498
[Presentation] 疾患iPS細胞を用いた破骨細胞分化系の構築と分化能の検討2014
- Author(s)
  伊藤眞理、村上美帆、丹羽明、齋藤潤、中畑龍俊、西本憲弘
- Organizer
  第1回日本骨免疫会議
- Place of Presentation
  万国津梁館
- Year and Date
  2014-07-01
- Data Source
  KAKENHI-PROJECT-26670498
[Presentation] Efficient and less labor-intensive methods for inducing vascular endothelial cells from human pluripotent stem cells.2014
- Author(s)
  Niwa Akira, Nakahata Tatsutoshi, Saito Megumu
- Organizer
  ISSCR 12th Annual Meeting
- Place of Presentation
  Vancouver Convention Center(CANADA)
- Year and Date
  2014-06-18
- Data Source
  KAKENHI-PROJECT-26670498
[Presentation] 疾患特異的iPS細胞を用いたChediak-東症候群の病態解析2014
- Author(s)
  王茂治、丹羽明、齋藤潤、中畑龍俊
- Organizer
  第35回日本炎症・再生医学会
- Place of Presentation
  万国津梁館
- Year and Date
  2014-07-02
- Data Source
  KAKENHI-PROJECT-26670498
[Presentation] Modeling Chediak-Higashi Syndrome using patient’s specific iPS cells.2014
- Author(s)
  Shigeharu Oh, Akira Niwa, Megumu K. Saito, Tatsutoshi Nakahata
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-10-31
- Data Source
  KAKENHI-PROJECT-26670498
[Presentation] 末梢血Natural Killer細胞を用いた人口多能性幹細胞の樹立2014
- Author(s)
  桐野浩輔、尾崎富美子、丹羽明、中畑龍俊、齋藤潤、平家勇司
- Organizer
  第35回日本炎症・再生医学会
- Place of Presentation
  万国津梁館
- Year and Date
  2014-07-02
- Data Source
  KAKENHI-PROJECT-26670498
[Presentation] Mesodermal development from reprogrammed Fanconi anemia cells is affected by ALDH2 enzymatic　activity.2013
- Author(s)
  Suzuki N., Hira A., Niwa A., Matsuo K., Takata　M., Yabe M., Nakahata T., Saito　M.
- Organizer
  11th Annual Meeting of international Society for Stem Cell Research (ISSCR)
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-24659496
[Presentation] Mesodermal development from reprogrammed Fanconi anemia cells is affected by ALDH2 enzymatic activity2013
- Author(s)
  Suzuki N., Hira A., Niwa A., Matsuo K., Takata M., Yabe M., Nakahata T., Saito M.
- Organizer
  11th Annual Meeting of international Society for Stem Cell Research (ISSCR)
- Place of Presentation
  Boston, MA, USA
- Data Source
  KAKENHI-PROJECT-24659496
[Presentation] NOGマウスを用いたTAMの病態解析2012
- Author(s)
  才田聡、渡邉健一郎、宮野悟、加藤格、森嶋達也、梅田雄嗣、平松英文、藤野寿典、足立壮一、丹羽明、中畑龍俊、伊藤悦朗、小川誠司、平家俊男他７名１８番目
- Organizer
  第54回日本小児血液・がん学会学術集会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24659496
[Presentation] HUMAN ESC/IPSC-DERIVED MESENCHYMAL STROMA CAN SUPPORT HEMATOPOIETIC PROGENITORS.2012
- Author(s)
  Niwa A., Saito M., Oshima K., Yanagimachi M., Tanaka T., Kato I., Nakahata,T.
- Organizer
  10th Annual Meeting of International Society for Stem Cell Research (ISSCR)
- Place of Presentation
  Pacifico Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-22249042
[Presentation] Differentiation of monocytic lineage cells from human iPS cells by using a serum and feeder free culture method.2012
- Author(s)
  Yanagimachi M, Niwa A, Tanaka T Oshima K, Saito M Nakahata T
- Organizer
  10th Annual Meeting of International Society for Stem Cell Research (ISSCR)
- Place of Presentation
  Pacifico Yokohama
- Data Source
  KAKENHI-PROJECT-24659496
[Presentation] DIFFERENTIATION OF MONOCYTIC LINEAGE CELLS FROM HUMAN IPS CELLS BY USING A SERUM AND FEEDER FREE CULTURE METHOD2012
- Author(s)
  Yanagimachi M., Niwa A., Tanaka T., Oshima K., Saito M., Nakahata T.
- Organizer
  10th Annual Meeting of International Society for Stem Cell Research (ISSCR)
- Place of Presentation
  Pacifico Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-22249042
[Presentation] Human ESC/IPSC-Derived mesenchymal stroma can support hematopoietic progenitors2012
- Author(s)
  Niwa A., Saito M., Oshima K., Yanagimachi M., Tanaka T., Kato I., Nakahata T.
- Organizer
  10◎<th>◎ Annual Meeting of International Society for Stem Cell Research (ISSCR)
- Place of Presentation
  Pacifico Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-24659496
[Presentation] Mesodermal development from reprogrammed Fanconi anemia cells is affected by ALDH2 enzymatic activity.2012
- Author(s)
  Suzuki N., Hira A., Niwa A., Saito M., Matsuo K., Nakahata T., Takata M., Yabe M.
- Organizer
  54th Annual Meeting of the AMERICAN SOCIETY of HEMATOLOGY
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-22249042
[Presentation] INDUCED PLURIPOTENT STEM CELL MODEL OF SEVERE CONGENITAL NEUTROPENIA WITH HAX1 GENE DEFICIENCY.2012
- Author(s)
  Morishima T., Watanabe K., Niwa A., Tanaka T., Saida S., Kato I., UmedaK., Hiramatsu H., Matsubara K., Adachi S., Nakahata T., Heike T.
- Organizer
  10th Annual Meeting of International Society for Stem Cell Research (ISSCR)
- Place of Presentation
  Pacifico Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-22249042
[Presentation] iPS細胞から単球・樹状細胞の分化誘導と疾患iPS細胞研究への応用2012
- Author(s)
  柳町昌克、丹羽明、田中孝之、村田祐樹、八角高裕、金澤伸雄、平家俊男、中畑龍俊、斎藤潤
- Organizer
  第5回自己炎症疾患研究会
- Place of Presentation
  福岡朝日ビル
- Data Source
  KAKENHI-PROJECT-24659496
[Presentation] Mesodermal development from reprogrammed Fanconi anemia cells is affected by ALDH2 enzymatic activity.2012
- Author(s)
  Suzuki N., Hira A., Niwa A., Saito M., Matsuo K., Nakahata T., Takata M., Yabe M.
- Organizer
  54th Annual Meeting of the AMERICAN SOCIETY of HEMATOLOGY
- Place of Presentation
  GeorGia World ConGress Center,Atlanta
- Data Source
  KAKENHI-PROJECT-24659496
[Presentation] Induced pluripotent stem cell model of severe congenital neutropenia with HAX1 gene deficiency.2012
- Author(s)
  Morishima T, Watanabe K, Niwa A, Tanaka T, Saida S, Kato I, Umeda K, Hiramatsu H, Matsubara K, Adachi S, Nakahata T, Heike T
- Organizer
  10th Annual Meeting of International Society for Stem Cell Research (ISSCR)
- Place of Presentation
  Pacifico Yokohama
- Data Source
  KAKENHI-PROJECT-24659496
[Presentation] Differentiation of monocytic lineage cells from human iPS cells by using a serum and feeder free culture method2012
- Author(s)
  Yanagimachi M., Niwa A., Tanaka T. Oshima K., Saito M., Nakahata T.
- Organizer
  10◎<th>◎ Annual Meeting of International Society for Stem Cell Research (ISSCR)
- Place of Presentation
  Pacifico Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-24659496
[Presentation] Induced pluripotent stem cell model of severe congenital neutropenia with HAX1 gene deficiency2012
- Author(s)
  Morishima T., Watanabe K., Niwa A., Tanaka T, Saida S, Kato I, Umeda K, Hiramatsu H., Matsubara K., Adachi S., Nakahata T., Heike T.
- Organizer
  10th Annual Meeting of International Society for Stem Cell Research (ISSCR)
- Place of Presentation
  Pacifico Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-24659496
[Presentation] Human ESC/IPSC-Derived mesenchymal stroma can support hematopoietic progenitors.2012
- Author(s)
  Niwa A.
- Organizer
  10th Annual Meeting of International Society for Stem Cell Research (ISSCR)
- Place of Presentation
  Pacifico Yokohama
- Data Source
  KAKENHI-PROJECT-22249042
[Presentation] Human ESC/IPSC-Derived mesenchymal stroma can support hematopoietic progenitors.2012
- Author(s)
  Niwa A, Saito M, Oshima K, Yanagimachi M, Tanaka T, Kato I, Nakahata T
- Organizer
  10th Annual Meeting of International Society for Stem Cell Research (ISSCR)
- Place of Presentation
  Pacifico Yokohama
- Data Source
  KAKENHI-PROJECT-24659496
[Presentation] Analysis of CNS Leukemic Microenviromerits through Xenograft Model In NOG Mouse2011
- Author(s)
  Itaru Kato, Hidefumi Hiramatsu, Akira Niwa, Satoshi Saida, Mamoru Ito, Ken-ichiro Watanabe, Souichi Adachi, Fumihiko Ishikawa, Tatsutoshi Nakahata, Toshio Heike
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋国際会議場(名古屋市)
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PROJECT-22249042
[Presentation] PRIMITIVE AND DEFINITIVE HEMATOPOIESIS OF HUMAN ES AND IPS CELLS IN SERUM-FREE MONOLAYER CULTURE CONDITION2011
- Author(s)
  丹羽明
- Organizer
  ISSCR 8^<th> Annual Meeting
- Place of Presentation
  サンフランシスコ
- Year and Date
  2011-02-05
- Data Source
  KAKENHI-PROJECT-22790979
[Presentation] ヒト多能性幹細胞由来造血支持細胞を用いた、二次元無血清条件における造血分化能の定量的評価の試み2011
- Author(s)
  丹羽明, 平家俊男, 梅田雄嗣, 大嶋宏一, 加藤格, 末盛博文, 中畑龍俊, 斎藤潤
- Organizer
  日本再生医療学会
- Place of Presentation
  東京
- Year and Date
  2011-03-09
- Data Source
  KAKENHI-PROJECT-22790979
[Presentation] ヒト多能性幹細胞由来造血支持細胞を用いた、二次元無血清条件における造血分化能の定量的評価の試み2011
- Author(s)
  丹羽明
- Organizer
  第10回日本再生医療学会
- Place of Presentation
  東京
- Year and Date
  2011-03-10
- Data Source
  KAKENHI-PROJECT-22790979
[Presentation] iPS細胞を用いた先天性造血不全疾患の解析への取り組み2011
- Author(s)
  丹羽明
- Organizer
  先天性造血不全シンポジウム
- Place of Presentation
  浦安
- Year and Date
  2011-02-05
- Data Source
  KAKENHI-PROJECT-22790979
[Presentation] ヒト多能性幹細胞を用いた、二次元無血清培養による段階的造血分化誘導2010
- Author(s)
  丹羽明, 平家俊男, 梅田雄嗣, 大嶋宏一, 加藤格, 末盛博文, 中畑龍俊, 斎藤潤
- Organizer
  日本血液学会
- Place of Presentation
  横浜
- Year and Date
  2010-10-11
- Data Source
  KAKENHI-PROJECT-22790979
[Presentation] ヒト多能性幹細胞を用いた、二次元無血清培養による段階的造血分化誘導2010
- Author(s)
  丹羽明
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2010-10-11
- Data Source
  KAKENHI-PROJECT-22790979
[Presentation] ヒトES/iPS細胞を用いた、二次元無血清条件による造血幹前駆細胞および成熟血球誘導の試み2010
- Author(s)
  丹羽明
- Organizer
  第33回日本造血細胞移植学会
- Place of Presentation
  松山
- Year and Date
  2010-10-11
- Data Source
  KAKENHI-PROJECT-22790979
[Presentation] ヒトES/iPS細胞からのin vitro二次元無血清造血誘導における、分化過程の経時的解析2010
- Author(s)
  丹羽明
- Organizer
  第31回日本炎症・再生医学会
- Place of Presentation
  東京
- Year and Date
  2010-08-05
- Data Source
  KAKENHI-PROJECT-22790979
[Presentation] In Vitro Orderly Haematopoiesis From Human Pluripotent Cells Traced In a Novel Monolayer Serum-Free Culture2010
- Author(s)
  Niwa A, Heike T, Umeda K, Oshima K, KatoI, Sakai H, Suemori H, Nakahata T and Saito M
- Organizer
  American Society of Hematology, 52st Annual Meeting
- Place of Presentation
  Orlando, Florida, USA
- Data Source
  KAKENHI-PROJECT-22790979
[Presentation] Tracing the developmental route from human ESC/iPSCs to blood via mesoderm in Serum-free 2D culture.2010
- Author(s)
  Niwa A., Heike T., Umeda K., Ohima K., Kato I., Suemori H., Saito M., Nakahata T.
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-22249042
[Presentation] ヒトES/iPS細胞からのin vitro二次元無血清造血誘導における、分化過程の経時的解析2010
- Author(s)
  丹羽明、中畑龍俊, 他5名
- Organizer
  第31回日本炎症・再生医学会
- Place of Presentation
  京王プラザホテル
- Year and Date
  2010-08-05
- Data Source
  KAKENHI-PROJECT-22249042
[Presentation] Primitive and definitive hematopoiesis of human ES and iPS cells in serum-free monolayer culture condition2010
- Author(s)
  Niwa A, Saito M1, Kato I, Oshima K, Heike T, Nakahata T
- Organizer
  ISSCR, Annual Meeting
- Place of Presentation
  SanFrancisco, USA
- Data Source
  KAKENHI-PROJECT-22790979
[Presentation] ヒトES/iPS細胞からのin vitro二次元無血清造血誘導における分化過程の経時的解析2010
- Author(s)
  丹羽明, 平家俊男, 梅田雄嗣, 大嶋宏一, 加藤格, 末盛博文, 中畑龍俊, 斎藤潤
- Organizer
  炎症再生医学会
- Place of Presentation
  東京
- Year and Date
  2010-07-09
- Data Source
  KAKENHI-PROJECT-22790979
[Presentation] Tracing the developmental route from human ESC/iPSCs to blood cia mesoderm in Serum-free 2D culture2010
- Author(s)
  Niwa A, Nakahata T., 他6名
- Organizer
  72回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-22249042
[Presentation] PSC-DERIVED HEMATOPOIETIC CELLS AS A NEW TOOL FOR EXPLORING LEUKEMIA PATHOGENESIS
- Author(s)
  丹羽　明
- Organizer
  第13回国際幹細胞研究会議（ISSCR 2015）
- Place of Presentation
  ストックホルム
- Year and Date
  2015-06-24 – 2015-06-27
- Data Source
  KAKENHI-PROJECT-25860856
[Presentation] Phenomic Screen to Explore Novel Pathogenesis of AML1-ETO-Positive Leukemia Using PSC-Derived Hematopoietic Cells
- Author(s)
  丹羽　明
- Organizer
  第56回米国血液学会（ASH 2014）
- Place of Presentation
  サンフランシスコ
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-25860856
[Presentation] Phenomic Screen in Vivo and in Vitro to Explore Novel Pathogenesis of AML1-ETO-Positive Leukemia Using PSC-Derived Hematopoietic Cells.
- Author(s)
  Akira Niwa, Akitsu Hotta, Megumu K Saito, Tatsutoshi Nakahata
- Organizer
  56th Annual Meeting of the AMERICAN SOCIETY of HEMATOLOGY
- Place of Presentation
  Mascone Convention Center(San Francisco,USA)
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-26670498
[Presentation] Exploring the Pathogenesis of Down Syndrome-Related Myeloproliferative Disorders Using iPSCs.
- Author(s)
  Nishinaka Yoko, Akira Niwa, Mitsujiro Osawa,, Akira Watanabe, Tatsutoshi Nakahata,, Megumu K Saito
- Organizer
  56th Annual Meeting of the AMERICAN SOCIETY of HEMATOLOGY
- Place of Presentation
  Mascone Convention Center(San Francisco,USA)
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-26670498

1. NAKAHATA Tatsutoshi (20110744)

# of Collaborated Projects: 3 results

# of Collaborated Products: 38 results
2. OSHIMA Koichi (60525377)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
3. SAITO Megumu (90535486)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Osawa Mitsujiro (70546770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. Mukasa Akitake (90463869)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SAITO Kuniaki (50446564)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NAKAMURA Eijiro (90293878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Kimura Hideki (20283187)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 田中將太 (80643725)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 山内高弘 (90291377)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 鳥居国雄 (40534045)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SAITOH Megumu

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results
13. WATANABE Kenichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 平位秀世

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 平家俊男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 犬飼岳史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 渡邊敦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Niwa Akira 丹羽 明

丹羽 明 ニワ アキラ

NIWA Akira 丹羽 明

Research Projects

Research Products

Co-Researchers

Investigation of new erythropoietin resistance factors and the mechanisms: with special attentions to associations between erythropoiesis and lipid metabolism

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Review Section

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Study on the clonal evolution of leukemia induced with internal mutatorsPrincipal Investigator

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Induction and expansion of PSC-derived HSCs by manipulating culture microenvironment

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Identification of causative genes for hemangioblastoma to elucidate the mechanisms of neovascularization and to develop novel therapeutic strategies

Principal Investigator

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Phenomic Screen to Explore Novel Pathogenesis of Leukemia Using PSC-Derived Hematopoietic CellsPrincipal Investigator

Principal Investigator

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Hematopoietic stem cell potential is propagated by human pluripotent stem cell-derived endothelial stroma

Principal Investigator

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Recapitulation of phenotypes and discovery of a novel treatment with disease-specific human ES/ iPS cells from various hereditary diseases

Principal Investigator

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Induction of hematopoietic stem/progenitor cells and functional blood cells from human ES/iPS cellsPrincipal Investigator

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[Book] 幹細胞の体外増幅法の現状と将来医学のあゆみ2012

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[Book] iPS細胞からの造血分化Annual Review血液2009

Author(s)

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[Book] 疾患由来iPS細胞の樹立分子細胞治療2009

Author(s)

Publisher

Data Source

[Book] ES, iPS細胞からの機能的赤血球産生血液フロンティア2009

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[Journal Article] Specific Antileukemic Activity of PD0332991, a CDK4/6 Inhibitor, against Philadelphia Chromosome-Positive Lymphoid Leukemia.2016

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DOI

Data Source

[Journal Article] Pluripotent cell models of Fanconi anemia identify the early pathological defect in human hemoangiogenic progenitors.2015

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DOI

NAID

Niwa Akira 丹羽明

丹羽明ニワアキラ

NIWA Akira 丹羽明