yui yoshihiro 由井理洋

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Yui Yoshihiro 由井理洋

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Researcher Number	20547757
Other IDs
Affiliation (Current)	2025: 医療法人徳洲会野崎徳洲会病院(附属研究所), 研究所, 主任研究員
Affiliation (based on the past Project Information) *help	2018 – 2024: 医療法人徳洲会野崎徳洲会病院(附属研究所), 研究所, 主任研究員
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related
Keywords	Principal Investigator 肺転移 / 骨肉腫 / 機械的シグナル伝達 / RNA-seq解析 / CRISPR活性化スクリーニング / 線維化 / 肺線維化 / 線維化抑制薬 / 線維化抑制剤 / 転移

骨肉腫細胞が軟らかい環境で増殖するメカニズムは肺転移の治療標的となるか？Principal Investigator
- Principal Investigator
  
  由井理洋
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  医療法人徳洲会野崎徳洲会病院(附属研究所)
Elucidation of scaffold-dependent pulmonary growth mechanisms in osteosarcoma and their application to therapy for inhibiting pulmonary metastasisPrincipal Investigator
- Principal Investigator
  
  Yui Yoshihiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  医療法人徳洲会野崎徳洲会病院(附属研究所)
Lung fibrosis is a novel therapeutic target to suppress lung metastasis of osteosarcomaPrincipal Investigator
- Principal Investigator
  
  Yui Yoshihiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  医療法人徳洲会野崎徳洲会病院(附属研究所)

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer risk2024
- Author(s)
  Northey Jason J.、Hayward Mary-Kate、Yui Yoshihiro、Stashko Connor、Kai FuiBoon、Mouw Janna K.、Thakar Dhruv、Lakins Jonathon N.、Ironside Alastair J.、Samson Susan、Mukhtar Rita A.、Hwang E. Shelley、Weaver Valerie M.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 31 Issue: 1 Pages: 106-126.e13
- DOI
  10.1016/j.stem.2023.12.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K09290
[Journal Article] Genetic characterization of a novel organoid from human malignant giant-cell tumor2023
- Author(s)
  Suzuki Rie、Wakamatsu Toru、Yoshida Keiichi、Matsuoka Yukiko、Takami Haruna、Nakai Sho、Tamiya Hironari、Kakunaga Shigeki、Yagi Toshinari、Yoshida Ken-ichi、Imura Yoshinori、Yui Yoshihiro、Sasagawa Satoru、Takenaka Satoshi
- Journal Title
  
  Journal of Bone Oncology
  
  Volume: 41 Pages: 100486-100486
- DOI
  10.1016/j.jbo.2023.100486
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16766, KAKENHI-PROJECT-23K08600, KAKENHI-PROJECT-21K09290, KAKENHI-PROJECT-21K09338
[Journal Article] Establishment of organoids from human epithelioid sarcoma with the air-liquid interface organoid cultures.2022
- Author(s)
  Wakamatsu T, Ogawa H, Yoshida K, Matsuoka Y, Shizuma K, Imura Y, Tamiya H, Nakai S, Yagi T, Nagata S, Yui Y, Sasagawa S, Takenaka S
- Journal Title
  
  Front. Oncol.
  
  Volume: 12 Pages: 893592-893592
- DOI
  10.3389/fonc.2022.893592
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09290, KAKENHI-PROJECT-21K09338, KAKENHI-PROJECT-22K16766, KAKENHI-PROJECT-19K18481, KAKENHI-PROJECT-20K18048
[Journal Article] Lung fibrosis is a novel therapeutic target to suppress lung metastasis of osteosarcoma2022
- Author(s)
  Yui Yoshihiro、Kumai Jun、Watanabe Kenta、Wakamatsu Toru、Sasagawa Satoru
- Journal Title
  
  International Journal of Cancer
  
  Volume: - Issue: 5 Pages: 739-751
- DOI
  10.1002/ijc.34008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09051, KAKENHI-PROJECT-19K18482, KAKENHI-PROJECT-21K09290, KAKENHI-PROJECT-21K09338
[Journal Article] Molecular evidence of IGFBP-3 dependent and independent VD3 action and its nonlinear response on IGFBP-3 induction in prostate cancer cells2020
- Author(s)
  Igarashi Ko、Yui Yoshihiro、Watanabe Kenta、Kumai Jun、Nishizawa Yasuko、Miyaura Chisato、Inada Masaki、Sasagawa Satoru
- Journal Title
  
  BMC Cancer
  
  Volume: 20 Issue: 1 Pages: 802-802
- DOI
  10.1186/s12885-020-07310-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09051, KAKENHI-PROJECT-19K18482, KAKENHI-PROJECT-19KK0194, KAKENHI-PROJECT-18H02571, KAKENHI-PROJECT-18K16641, KAKENHI-PROJECT-20H02534
[Journal Article] Low-dose eribulin reduces lung metastasis of osteosarcoma in vitro and in vivo.2019
- Author(s)
  Watanabe K, Yui Y, Sasagawa S, Suzuki K, Kanamori M, Yasuda T, Kimura T.
- Journal Title
  
  Oncotarget
  
  Volume: 10(2) Issue: 2 Pages: 161-174
- DOI
  10.18632/oncotarget.26536
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09051, KAKENHI-PROJECT-18K16641, KAKENHI-PROJECT-17K10961, KAKENHI-PROJECT-17K16681
[Journal Article] Evidence for intrathecal sodium butyrate as a novel option for leptomeningeal metastasis.2018
- Author(s)
  Nakagawa H, Yui Y, Sasagawa S, Itoh K.
- Journal Title
  
  Journal of Neuro-Oncology
  
  Volume: 印刷中 Issue: 1 Pages: 43-50
- DOI
  10.1007/s11060-018-2852-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10458, KAKENHI-PROJECT-15K15560, KAKENHI-PROJECT-18K09051, KAKENHI-PROJECT-18K16641
[Presentation] 肺線維化は骨肉腫肺転移の治療標的になりうる2022
- Author(s)
  Yoshihiro Yui, Toru Wakamatsu, Satoru Sasagawa
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K09290
[Presentation] 線維化抑制剤による骨肉腫の肺転移抑制の可能性2021
- Author(s)
  Yui Yoshihiro、Kumai Jun、Watanabe Kenta、Wakamatsu Toru、Sasagawa Satoru
- Organizer
  第30回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-21K09290
[Presentation] 骨肉腫の肺転移形成は肺の線維化に依存する2019
- Author(s)
  由井　理洋、熊井　準、渡邉　健太, 笹川　覚、中　紀文
- Organizer
  第78回　日本癌学会学術総会 (ポスター発表)
- Data Source
  KAKENHI-PROJECT-18K16641
[Presentation] 細胞外マトリックスの硬度から見た骨肉腫転移メカニズムの解明2019
- Author(s)
  熊井準、渡邊健太、笹川覚、由井理洋
- Organizer
  日本薬学会第139年会 (ポスター発表)
- Data Source
  KAKENHI-PROJECT-18K16641
[Presentation] 骨肉腫の肺転移形成は肺の線維化に依存する2019
- Author(s)
  由井　理洋、熊井　準、渡邉　健太, 笹川　覚、中　紀文
- Organizer
  第28回　日本がん転移学会学術集会・総会 (口頭発表)
- Data Source
  KAKENHI-PROJECT-18K16641
[Presentation] Low-dose eribulin suppresses lung metastasis of osteosarcoma in vitro and in vivo2019
- Author(s)
  Watanabe K, Yui Y, Sasagawa S, Suzuki K, Kanamori M, Yasuda T, Kimura T.
- Organizer
  AACR Annual Meeting 2019 (ポスター発表)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16641
[Presentation] Inhibitory effect of Eribulin on metastasis in mouse osteosarcoma2018
- Author(s)
  渡邉　健太, 由井　理洋, 笹川　覚, 安田　剛敏, 木村　友厚
- Organizer
  第51回日本整形外科学会骨・軟部腫瘍学術集会 (ポスター発表)
- Data Source
  KAKENHI-PROJECT-18K16641
[Presentation] エリブリンによる骨肉腫肺転移抑制効果の解析2018
- Author(s)
  由井　理洋, 渡邉　健太, 五十嵐　晃,笹川　覚, 安田　剛敏, 木村　友厚
- Organizer
  第27回日本がん転移学会学術集会・総会 (ポスター発表)
- Data Source
  KAKENHI-PROJECT-18K16641
[Presentation] エリブリンによる骨肉腫肺転移抑制効果の解析2018
- Author(s)
  由井　理洋, 渡邉　健太, 五十嵐　晃,笹川　覚, 安田　剛敏, 木村　友厚
- Organizer
  第77回日本癌学会学術総会 (ポスター発表)
- Data Source
  KAKENHI-PROJECT-18K16641

1. 伊村慶紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 笹川覚

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
3. 伊藤和幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

yui yoshihiro 由井 理洋

Yui Yoshihiro 由井 理洋

Research Projects

Research Products

Co-Researchers

骨肉腫細胞が軟らかい環境で増殖するメカニズムは肺転移の治療標的となるか？Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of scaffold-dependent pulmonary growth mechanisms in osteosarcoma and their application to therapy for inhibiting pulmonary metastasisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Lung fibrosis is a novel therapeutic target to suppress lung metastasis of osteosarcomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer risk2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genetic characterization of a novel organoid from human malignant giant-cell tumor2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Establishment of organoids from human epithelioid sarcoma with the air-liquid interface organoid cultures.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lung fibrosis is a novel therapeutic target to suppress lung metastasis of osteosarcoma2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Molecular evidence of IGFBP-3 dependent and independent VD3 action and its nonlinear response on IGFBP-3 induction in prostate cancer cells2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Low-dose eribulin reduces lung metastasis of osteosarcoma in vitro and in vivo.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evidence for intrathecal sodium butyrate as a novel option for leptomeningeal metastasis.2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] 肺線維化は骨肉腫肺転移の治療標的になりうる2022

Author(s)

Organizer

Data Source

[Presentation] 線維化抑制剤による骨肉腫の肺転移抑制の可能性2021

Author(s)

Organizer

Data Source

[Presentation] 骨肉腫の肺転移形成は肺の線維化に依存する2019

Author(s)

Organizer

Data Source

[Presentation] 細胞外マトリックスの硬度から見た骨肉腫転移メカニズムの解明2019

Author(s)

Organizer

Data Source

[Presentation] 骨肉腫の肺転移形成は肺の線維化に依存する2019

Author(s)

Organizer

Data Source

[Presentation] Low-dose eribulin suppresses lung metastasis of osteosarcoma in vitro and in vivo2019

Author(s)

yui yoshihiro 由井理洋

Yui Yoshihiro 由井理洋