Taguchi Hiroaki 田口博明

… Alternative Names

TAGUCHI Hiroaki 田口博明

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Researcher Number	20549068
Other IDs
Affiliation (Current)	2025: 鈴鹿医療科学大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2018 – 2023: 鈴鹿医療科学大学, 薬学部, 教授 2012 – 2014: 鈴鹿医療科学大学, 薬学部, 准教授
Review Section/Research Field	Principal Investigator Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Drug development chemistry Except Principal Investigator Basic Section 49050:Bacteriology-related / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Basic Section 37010:Bio-related chemistry
Keywords	Principal Investigator タウタンパク質 / 抗体酵素 / 2機能性抗体酵素 / クリックケミストリー / アミロイドベータ / アミロイド / アルツハイマー病 / ペプチド / 抗体医薬 / タウオパチー / 医薬品化学 … More Except Principal Investigator … More 標的分子 / カンジダ / 真菌感染症 / 薬剤耐性 / トランスポーター / 脂質輸送 / ステロール / 鉄代謝 / 真菌 / 病原性発現 / 鉄欠乏ストレス / タウ蛋白 / アミロイド / 抗体酵素 / scFv様分子 / 認知症 / Tauタンパク質 / β-amyloid / スーパー抗体酵素 / two functional / catalytic antibody / Tau protein / beta-amyloid Less

Analysis of cholesterol uptake and transport from host serum in pathogenic fungi
- Principal Investigator
  
  中山浩伸
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Suzuka University of Medical Science
Development of bifunctional catalytic antibody aiming at innovative therapeutic drug for Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  Taguchi Hiroaki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Suzuka University of Medical Science
Analysis of iron homeostasis of pathogenic fungi to aim development of a novel antifungal
- Principal Investigator
  
  Nakayama Hironobu
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Suzuka University of Medical Science
Development of a two functional super catalytic antibody for the treatment of dementia
- Principal Investigator
  
  Uda Taizo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37010:Bio-related chemistry
- Research Institution
  Institute of Systems, Information Technologies and Nanotechnologies
Development of innovative tauopathy therapeutic agents using catalytic antibodiesPrincipal Investigator
- Principal Investigator
  
  Taguchi Hiroaki
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Suzuka University of Medical Science
Development of antibodies with Abeta hydrolyzing activity for treatment of Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  TAGUCHI Hiroaki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Suzuka University of Medical Science

All 2024 2023 2022 2021 2020 2019 2018 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Increasing Hydrolytic Activity of Catalytic Antibody by Deletion of Pro95 in CDR32024
- Author(s)
  Satoshi Nakagawa、Naoya Hatsuyama、Emi Hifumi、Taizo Uda、Hiroaki Taguchi
- Journal Title
  
  Peptide science
  
  Volume: 59
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06486
[Journal Article] Direct conversion of a general antibody to its catalytic antibody and corresponding applications —Importance and role of Pro95 in CDR-3—2023
- Author(s)
  HIFUMI Emi、TAGUCHI Hiroaki、NONAKA Tamami、UDA Taizo
- Journal Title
  
  Proceedings of the Japan Academy, Series B
  
  Volume: 99 Issue: 6 Pages: 155-172
- DOI
  10.2183/pjab.99.010
- ISSN
  0386-2208, 1349-2896
- Year and Date
  2023-06-19
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06486
[Journal Article] A new catalytic site functioning in antigen cleavage by H34 catalytic antibody light chain2022
- Author(s)
  Hifumi Emi、Nonaka Tamami、Taguchi Hiroaki、Uda Taizo
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 19185-19185
- DOI
  10.1038/s41598-022-23689-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06486, KAKENHI-PROJECT-20K21255
[Journal Article] Obtaining Highly Active Catalytic Antibodies Capable of Enzymatically Cleaving Antigens2022
- Author(s)
  Nonaka Tamami、Taguchi Hiroaki、Uda Taizo、Hifumi Emi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 22 Pages: 14351-14351
- DOI
  10.3390/ijms232214351
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06486, KAKENHI-PROJECT-20K21255
[Journal Article] Finding and characterizing a catalytic antibody light chain, H34, capable of degrading the PD-1 molecule2021
- Author(s)
  Hifumi Emi、Taguchi Hiroaki、Nonaka Tamami、Harada Takunori、Uda Taizo
- Journal Title
  
  RSC Chemical Biology
  
  Volume: 2 Issue: 1 Pages: 220-229
- DOI
  10.1039/d0cb00155d
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06589, KAKENHI-PROJECT-20K21255, KAKENHI-PROJECT-18K05062
[Journal Article] A new algorithm to convert a normal antibody into the corresponding catalytic antibody2020
- Author(s)
  Emi Hifumi, Hiroaki Taguchi, Haruna Tsuda, Tetsuro Minagawa, Tamami Nonaka, and Taizo Uda
- Journal Title
  
  Sci Adv.
  
  Volume: 6 Issue: 13 Pages: 6441-6441
- DOI
  10.1126/sciadv.aay6441
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06589, KAKENHI-PROJECT-16H02282
[Journal Article] Discovery of Antibody Light Chains Possessing Tau Protein-Hydrolyzing Activity2020
- Author(s)
  Hiroaki Taguchi1, Yuki Kato, Taminao Ito, Emi Hifumi, and Taizo Uda
- Journal Title
  
  Peptide science
  
  Volume: 56 Pages: 139-140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06589
[Journal Article] Discovery of Antibody Light Chains Possessing Tau Protein- Hydrolyzing Activity2020
- Author(s)
  Hiroaki Taguchi, Yuki Kato, Taminao Ito, Emi Hifumi, and Taizo Uda
- Journal Title
  
  Peptide　science　2019
  
  Volume: 56 Pages: 139-140
- Data Source
  KAKENHI-PROJECT-18K05328
[Journal Article] Discovery of Antibody Light Chains Capable of Hydrolyzing Tau Protein Using Fluorescence-Quenched Substrate2019
- Author(s)
  Hiroaki Taguchi, Iida Yuki, Mao Oba, Yoshio Fujita, Emi Hifumi, Taizo Uda
- Journal Title
  
  Peptide　science　2018
  
  Volume: 55 Pages: 40-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06589
[Journal Article] Identification of the minimal region of peptide derived from ADP-ribosylation factor1 (ARF1) that inhibits IgE-mediated mast cell activation2019
- Author(s)
  Uchida Ryota、Egawa Tomonori、Fujita Yoshio、Furuta Kazuyuki、Taguchi Hiroaki、Tanaka Satoshi、Nishida Keigo
- Journal Title
  
  Molecular Immunology
  
  Volume: 105 Pages: 32-37
- DOI
  10.1016/j.molimm.2018.11.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08273, KAKENHI-PROJECT-18K06589, KAKENHI-PROJECT-16K08231, KAKENHI-PROJECT-16K15152, KAKENHI-PROJECT-20K20320
[Journal Article] New technologies to introduce a catalytic function into antibodies: A unique human catalytic antibody light chain showing degradation of β‐amyloid molecule along with the peptidase activity2019
- Author(s)
  Emi Hifumi, Hiroaki Taguchi, Eiichi Toorisaka, Taizo Uda
- Journal Title
  
  FASEB BioAdvances
  
  Volume: 1 Issue: 2 Pages: 93-104
- DOI
  10.1096/fba.1025
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06589, KAKENHI-PROJECT-16H02282
[Journal Article] Discovery of antibody light chains capable of hydrolyzing tau protein using fluorescence-quenched substrate2019
- Author(s)
  Hiroaki Taguchi, Iida Yuki, Mao Oba, Yoshio Fujita, Emi Hifumi, Taizo Uda
- Journal Title
  
  Peptide　science　2018
  
  Volume: 55 Pages: 40-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05328
[Journal Article] Effects of Physical Damage in the Intermediate Phase on the Progression of Amyloid β Fibrillization2019
- Author(s)
  Ryu Tashiro, Hiroaki Taguchi, Kumi Hidaka, Masayuki Endo, Hiroshi Sugiyama
- Journal Title
  
  Chem. Asian J.
  
  Volume: 14 Issue: 23 Pages: 4140-4145
- DOI
  10.1002/asia.201901193
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06589, KAKENHI-PROJECT-18KK0139
[Journal Article] Synthesis of isopeptidyl phosphonate derivatives2015
- Author(s)
  Taguchi H, Etou　D, Oode M, Oohashi S, Ogawa M, and Fujita Y.
- Journal Title
  
  Peptides 2014
  
  Volume: 33
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590151
[Journal Article] Specific Amyloid β Clearance by a Catalytic Antibody Construct2015
- Author(s)
  Planque SA, Nishiyama Y, Sonoda S, Lin Y, Taguchi H, Hara M, Kolodziej S, Mitsuda Y, Gonzalez V, Sait HB, Fukuchi K, Massey RJ, Friedland RP, O'Nuallain B,Sigurdsson EM, Paul S
- Journal Title
  
  J Biol Chem.
  
  Volume: 290 Issue: 16 Pages: 10229-10241
- DOI
  10.1074/jbc.m115.641738
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590151
[Journal Article] Synthesis and development of peptides directed to drugs2014
- Author(s)
  Taguchi H
- Journal Title
  
  Chemical Industry
  
  Volume: 65 Pages: 897-902
- NAID
  40020272329
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590151
[Journal Article] Synthesis and Biochemical Evaluation of Isopeptidyl Phosphonate Ester Derivatives containing Hydroxyl Group or Macrocyclic Polyamine2014
- Author(s)
  Taguchi, H., Ogawa, M., Oohashi, S., Fujita, Y.
- Journal Title
  
  Peptide Science
  
  Volume: 50 Pages: 153-154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590151
[Journal Article] Metal-dependent amyloid β-degrading catalytic antibody construct2014
- Author(s)
  Nishiyama Y., Taguchi H., Hara M., Planque S.A., Mitsuda Y., and Paul S
- Journal Title
  
  J Biotechnol
  
  Volume: 180 Pages: 17-22
- DOI
  10.1016/j.jbiotec.2014.03.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590151
[Journal Article] Design and Synthesis of Peptidyl Phosphonate for Isolation of Antibodies with Hydrolyzing Activity2013
- Author(s)
  Hiroaki Taguchi, Yoshio Fujita, Yuko Tsuda
- Journal Title
  
  Peptide Science
  
  Volume: 49 Pages: 301-302
- NAID
  10031161635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590151
[Journal Article] Design and synthesis of biotinylated peptidyl phosphonate probe for the isolation of single chain Fv with hydrolyzing activity2013
- Author(s)
  Hiroaki Taguchi, Yoshio Fujita, Yuko Tsuda
- Journal Title
  
  Peptide 2012
  
  Volume: 32 Pages: 196-197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590151
[Presentation] α-シヌクレインのNAC部分を標的としたヒト型軽鎖抗体酵素の開発2024
- Author(s)
  田口博明、初山直哉、一二三恵美、宇田泰三
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-21K06486
[Presentation] α-シヌクレイン部分配列を含むペプチド性消光性基質の合成とヒト型抗体軽鎖のスクリーニング2023
- Author(s)
  田口博明、一色亮汰、松尾有紗、中川智士、一二三恵美、宇田泰三
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K06486
[Presentation] INCREASING HYDROLYTIC ACTIVITY OF CATALYTIC ANTIBODY BY DELETION OF PRO95 IN CDR32023
- Author(s)
  Satoshi Nakagawa, Naoya Hatsuyama, Emi Hifumi, Taizo Uda, Hiroaki Taguchi
- Organizer
  第60回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-21K06486
[Presentation] アデュカヌマブ軽鎖の抗体酵素化に関する研究2023
- Author(s)
  中川智士、水谷百恵、一二三恵美、宇田泰三、田口博明
- Organizer
  第69回　日本薬学会東海支部大会
- Data Source
  KAKENHI-PROJECT-21K06486
[Presentation] Inhibition of amyloid-beta aggregation by catalytic light chain antibodies2022
- Author(s)
  水谷百恵、一二三恵美、宇田泰三、田口博明
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-18K06589
[Presentation] Inhibition of amyloid-beta aggregation by catalytic light chain antibodies2022
- Author(s)
  水谷百恵、一二三恵美、宇田泰三、田口博明
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21K06486
[Presentation] α-シヌクレインを加水分解する抗体酵素の開発2022
- Author(s)
  田口博明、一色亮汰、松尾有紗、一二三恵美、宇田泰三
- Organizer
  第41回日本認知症学会
- Data Source
  KAKENHI-PROJECT-21K06486
[Presentation] アミロイドβペプチドを加水分解する抗体酵素の開発2021
- Author(s)
  田口博明、一二三恵美、宇田泰三
- Organizer
  第40回日本認知症学会
- Data Source
  KAKENHI-PROJECT-18K06589
[Presentation] ２種類の抗原(Tau＆Aβ)を同時分解する２機能型抗体酵素の作製と性質(II)2021
- Author(s)
  宇田泰三、田口博明、野中玲実、一二三恵美
- Organizer
  第１０１春季日本化学会年会
- Data Source
  KAKENHI-PROJECT-18K05328
[Presentation] アミロイドβペプチドを加水分解する抗体酵素の開発2021
- Author(s)
  田口博明、一二三恵美、宇田泰三
- Organizer
  第40回日本認知症学会
- Data Source
  KAKENHI-PROJECT-21K06486
[Presentation] 2種類の抗原(Tau＆Aβ)を同時分解する２機能型抗体酵素の作製と性質2020
- Author(s)
  宇田泰三、田口博明、一二三恵美
- Organizer
  第１００春季日本化学会年会
- Data Source
  KAKENHI-PROJECT-18K05328
[Presentation] タウタンパク質のリピート２部分を加水分解する抗体酵素の開発2020
- Author(s)
  田口博明、伊藤民直、加藤佑規、一二三恵美、宇田泰三
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-18K05328
[Presentation] Discovery of Antibody Light Chains Capable of Hydrolyzing Tau Protein Using Fluorescence-Quenched Substrate2019
- Author(s)
  Hiroaki Taguchi, Iida Yuki, Mao Oba, Yoshio Fujita, Emi Hifumi, Taizo Uda
- Organizer
  10th international peptide symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06589
[Presentation] Observation of growing amyloid protofibrils 2D network with high speed AFM2019
- Author(s)
  Ryu Tashiro, Hiroaki Taguchi, Kumi Hidaka, Masayuki Endo, Hiroshi Sugiyama
- Organizer
  日本ケミカルバイオロジー学会第14回年会
- Data Source
  KAKENHI-PROJECT-18K06589
[Presentation] タウタンパク質のリピート２部分を加水分解する抗体酵素の開発2019
- Author(s)
  田口博明、伊藤民直、加藤佑規、一二三恵美、宇田泰三
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-18K06589
[Presentation] Discovery of Antibody Light Chains Possessing Tau Protein- Hydrolyzing Activity2019
- Author(s)
  田口博明、伊藤民直、加藤佑規、一二三恵美、宇田泰三
- Organizer
  第56回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-18K05328
[Presentation] タウタンパク質を加水分解する抗体酵素の開発2019
- Author(s)
  田口博明、伊藤民直、加藤佑規、一二三恵美、宇田泰三
- Organizer
  第38回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-18K05328
[Presentation] Tauペプチドを分解するヒト型抗体軽鎖2019
- Author(s)
  宇田泰三・田口博明・一二三恵美
- Organizer
  第９９春季日本化学会年会
- Data Source
  KAKENHI-PROJECT-18K05328
[Presentation] タウタンパク質を加水分解する抗体酵素の開発2019
- Author(s)
  田口博明、伊藤民直、加藤佑規、一二三恵美、宇田泰三
- Organizer
  第38回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06589
[Presentation] Unique antigenases to enzymatically cleave Tau peptides at C- and N-terminal moieties2019
- Author(s)
  Taizo Uda, Hiroaki Taguchi, Emi Hifumi
- Organizer
  The 12th ECCE(European Congress of Chemical Engineering) & 5th ECAB(European Congress of Applied Biotechnology)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05328
[Presentation] Discovery of Antibody Light Chains Possessing Tau Protein-Hydrolyzing Activity2019
- Author(s)
  田口博明、伊藤民直、加藤佑規、一二三恵美、宇田泰三
- Organizer
  第56回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-18K06589
[Presentation] アミロイドβ1-42プロトフィブリルの伸長のリアルタイム観測2019
- Author(s)
  田代竜、田口博明、日高久美、遠藤政幸、杉山弘
- Organizer
  日本薬学会東海支部会
- Data Source
  KAKENHI-PROJECT-18K06589
[Presentation] Discovery of Antibody Light Chains Capable of Hydrolyzing Tau Protein Using Fluorescence-Quenched Substrate2018
- Author(s)
  Hiroaki Taguchi, Iida Yuki, Mao Oba, Yoshio Fujita, Emi Hifumi, Taizo Uda
- Organizer
  10th international peptide symposium
- Data Source
  KAKENHI-PROJECT-18K05328
[Presentation] 抗体医薬開発ツールとしてのリン酸ジエステル含有ペプチドの開発2015
- Author(s)
  田口博明
- Organizer
  第20回ペプチドフォーラム「生命分子・ペプチド機能に学ぶ医薬品」
- Place of Presentation
  滋賀県長浜市
- Year and Date
  2015-03-13
- Invited
- Data Source
  KAKENHI-PROJECT-24590151
[Presentation] 加水分解活性を有する抗体の誘導を目指した試薬の開発2014
- Author(s)
  衛藤大輝，大出慎，佐々木みく，森本佐知子，藤田快男，田口博明
- Organizer
  第60回日本薬学会東海支部大会
- Place of Presentation
  三重県鈴鹿市
- Year and Date
  2014-07-05
- Data Source
  KAKENHI-PROJECT-24590151
[Presentation] 水酸基を有するイソペプチドリン酸ジエステル誘導体の合成と酵素阻害活性評価2014
- Author(s)
  田口博明，衛藤大輝，大出慎，小川光広，大橋駿，藤田快男
- Organizer
  第134回日本薬学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24590151
[Presentation] Synthesis and Biochemical Evaluation of Isopeptidyl Phosphonate Ester Derivatives containing Hydroxyl Group or Macrocyclic Polyamine2013
- Author(s)
  Taguchi, H., Ogawa, M., Oohashi, S., Fujita, Y.
- Organizer
  4th Asia-Pacific international Peptide Symposium
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24590151
[Presentation] 水酸基を有するイソペプチドリン酸ジエステル誘導体の酵素阻害活性評価2013
- Author(s)
  小川光広，大橋駿，藤田快男，田口博明
- Organizer
  第59回日本薬学会東海支部大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24590151
[Presentation] 環状ポリアミンを含んだイソペプチドリン酸誘導体の合成と酵素阻害活性評価2013
- Author(s)
  大橋駿，小川光広，藤田快男，田口博明
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会
- Place of Presentation
  鈴鹿
- Data Source
  KAKENHI-PROJECT-24590151
[Presentation] 水酸基を有するイソペプチドリン酸誘導体の合成とそのトリプシン阻害活性2013
- Author(s)
  小川光広，大橋駿，藤田快男，田口博明
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会
- Place of Presentation
  鈴鹿
- Data Source
  KAKENHI-PROJECT-24590151
[Presentation] Synthesis of isopeptidyl phosphonate derivatives and their biochemical evaluation
- Author(s)
  Taguchi H, Etou　D, Oode M, Oohashi S, Ogawa M, and Fujita Y.
- Organizer
  33rd European Peptide Symposium
- Place of Presentation
  ブルガリア，ソフィア
- Year and Date
  2014-08-31 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-24590151
[Presentation] Design and synthesis of biotinylated peptidyl phosphonate probe for the isolation of single chain Fv with hydrolyzing activity
- Author(s)
  Hiroaki Taguchi, Yoshio Fujita, Yuko Tsuda
- Organizer
  32nd European Peptide Symposium
- Place of Presentation
  Athens, Greek
- Data Source
  KAKENHI-PROJECT-24590151
[Presentation] アミロイドβペプチド加水分解抗体の単離を指向したプローブの開発
- Author(s)
  田口博明，藤田快男，津田裕子
- Organizer
  日本ケミカルバイオロジー学会　第7回年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24590151
[Presentation] 環状ポリアミンを含んだペプチド性リン酸ジエステル誘導体の合成
- Author(s)
  田口博明，大橋駿，小川光広，藤田快男
- Organizer
  第133回日本薬学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24590151
[Presentation] 加水分解活性を有する抗体の単離を指向したペプチド性リン酸ジエステルのデザインと合成
- Author(s)
  田口博明，藤田快男，津田裕子
- Organizer
  第49回ペプチド討論会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-24590151
[Presentation] 部分アミロイドβペプチド配列を含む消光性蛍光基質の開発
- Author(s)
  田口博明，上村尚子，松島慶，藤田快男，
- Organizer
  第135回日本薬学会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24590151
[Presentation] 触媒抗体単離を目指したプローブの開発
- Author(s)
  田口博明，藤田快男，津田裕子
- Organizer
  第57回日本薬学会東海支部大会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-24590151

1. Nakayama Hironobu (40369989)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 一二三恵美 (90254606)

# of Collaborated Projects: 2 results

# of Collaborated Products: 20 results
3. 森田明広 (20382228)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. Uda Taizo (20232837)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
5. 古田和幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Taguchi Hiroaki 田口 博明

TAGUCHI Hiroaki 田口 博明

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Analysis of cholesterol uptake and transport from host serum in pathogenic fungi

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Development of bifunctional catalytic antibody aiming at innovative therapeutic drug for Alzheimer's diseasePrincipal Investigator

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Analysis of iron homeostasis of pathogenic fungi to aim development of a novel antifungal

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Development of a two functional super catalytic antibody for the treatment of dementia

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Development of innovative tauopathy therapeutic agents using catalytic antibodiesPrincipal Investigator

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Development of antibodies with Abeta hydrolyzing activity for treatment of Alzheimer's diseasePrincipal Investigator

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[Journal Article] Increasing Hydrolytic Activity of Catalytic Antibody by Deletion of Pro95 in CDR32024

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[Journal Article] Direct conversion of a general antibody to its catalytic antibody and corresponding applications —Importance and role of Pro95 in CDR-3—2023

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[Journal Article] A new catalytic site functioning in antigen cleavage by H34 catalytic antibody light chain2022

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[Journal Article] Obtaining Highly Active Catalytic Antibodies Capable of Enzymatically Cleaving Antigens2022

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[Journal Article] Finding and characterizing a catalytic antibody light chain, H34, capable of degrading the PD-1 molecule2021

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[Journal Article] A new algorithm to convert a normal antibody into the corresponding catalytic antibody2020

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[Journal Article] Discovery of Antibody Light Chains Possessing Tau Protein-Hydrolyzing Activity2020

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[Journal Article] Discovery of Antibody Light Chains Possessing Tau Protein- Hydrolyzing Activity2020

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Taguchi Hiroaki 田口博明

TAGUCHI Hiroaki 田口博明