KIZUKA YASUHIKO 木塚康彦

… Alternative Names

KIZUKA Yasuhiko 木塚康彦

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Researcher Number	20564743
Other IDs
Affiliation (Current)	2025: 岐阜大学, 糖鎖生命コア研究所, 教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 岐阜大学, 糖鎖生命コア研究所, 教授 2021: 岐阜大学, 糖鎖生命コア研究所, 准教授 2020: 岐阜大学, 高等研究院, 准教授 2017 – 2019: 岐阜大学, 研究推進・社会連携機構, 准教授 2015 – 2016: 国立研究開発法人理化学研究所, 疾患糖鎖研究チーム, 研究員 2012 – 2014: 独立行政法人理化学研究所, 疾患糖鎖研究チーム, 基礎科学特別研究員 2011: 独立行政法人理化学研究所, 疾患糖鎖研究チーム, 特別研究員
Review Section/Research Field	Principal Investigator Functional biochemistry / Basic Section 48040:Medical biochemistry-related / Basic Section 43030:Functional biochemistry-related / General medical chemistry / Biological Sciences Except Principal Investigator Medium-sized Section 38:Agricultural chemistry and related fields / Basic Section 40020:Wood science-related / Basic Section 48040:Medical biochemistry-related
Keywords	Principal Investigator 糖鎖 / 糖転移酵素 / アルツハイマー病 / 糖鎖生物学 / bisecting GlcNAc / GnT-III / バイセクト糖鎖 / エピジェネティクス / N型糖鎖 / GnT-IVa (MGAT4A) … More / GnT-V (MGAT5) / GnT-III (MGAT3) / がん / PRMT1 / GnT-V / HNK-1 / 脳 / BACE1 / miRNA / 糖鎖遺伝子 / 国際情報交流 / 国際情報交換 / 国際研究者交流 / HDAC / O-GlcNAc / GnT-IX … More Except Principal Investigator 細胞膜内層微小領域 / ケミカルバイオロジー / 超解像イメージング / 分子プローブ / 糖鎖―糖鎖相互作用 / 細胞膜内微小領域 / 生合成 / 酵素 / アラビノフラノース / フェルラ酸 / キシラン / 糖鎖 / がん / IgG / コアフコース Less

Mechanisms of protein-selective glycosylation regulated by unique domains of N-glycan branching enzymesPrincipal Investigator
- Principal Investigator
  
  木塚康彦
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Gifu University
Molecular basis of feruloylarabinoxylan biosynthetic engineering
- Principal Investigator
  
  鈴木史朗
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 40020:Wood science-related
- Research Institution
  Gifu University
An extedned research of cell membrane domains based on the probes of membrane molecules
- Principal Investigator
  
  安藤弘宗
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 38:Agricultural chemistry and related fields
- Research Institution
  Gifu University
Mechanisms of cancer and Alzheimer's disease involving glycan branchingPrincipal Investigator
- Principal Investigator
  
  Kizuka Yasuhiko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Gifu University
Modulation of cancer cells by core fucose-specific antibody
- Principal Investigator
  
  Taniguchi Naoyuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Osaka International Cancer Institute
Mechanisms of expression and action of neurodegeneration-promoting glycan bisecting GlcNAcPrincipal Investigator
- Principal Investigator
  
  Kizuka Yasuhiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Gifu University
神経系の糖鎖発現を規定するエピゲノム因子の探索Principal Investigator
- Principal Investigator
  
  木塚康彦
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Institute of Physical and Chemical Research
A novel trafficking mechanism regulated by bisecting GlcNAc, an Alzheimer's disease acceleratorPrincipal Investigator
- Principal Investigator
  
  Kizuka Yasuhiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Institute of Physical and Chemical Research
Epigenetic regulation of brain-specific O-mannose glycansPrincipal Investigator
- Principal Investigator
  
  KIZUKA Yasuhiko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  The Institute of Physical and Chemical Research

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation Book

[Book] 生化学2015
- Author(s)
  木塚康彦
- Publisher
  発行：日本生化学会
- Data Source
  KAKENHI-PUBLICLY-26110723
[Book] Epigenetic Regulation of and by Glycosylation (Glycoscience: Biology and Medicine)2014
- Author(s)
  Yasuhiko Kizuka (Taniguchi, N., Endo, T., Hart, G.W., Seeberger, P.H., Wong, C.H., eds)
- Total Pages
  5
- Publisher
  Springer
- Data Source
  KAKENHI-PUBLICLY-26110723
[Journal Article] N-acetylglucosaminyltransferase-V (GnT-V)-enriched small extracellular vesicles mediate N-glycan remodeling in recipient cells2023
- Author(s)
  Hirata Tetsuya、Harada Yoichiro、Hirosawa Koichiro M.、Tokoro Yuko、Suzuki Kenichi G.N.、Kizuka Yasuhiko
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 1 Pages: 105747-105747
- DOI
  10.1016/j.isci.2022.105747
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03207, KAKENHI-PROJECT-20H03225, KAKENHI-PROJECT-21H02424
[Journal Article] ER entry pathway and glycosylation of GPI-anchored proteins are determined by N-terminal signal sequence and C-terminal GPI-attachment sequence2022
- Author(s)
  Hirata Tetsuya、Yang Jing、Tomida Seita、Tokoro Yuko、Kinoshita Taroh、Fujita Morihisa、Kizuka Yasuhiko
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 298 Issue: 10 Pages: 102444-102444
- DOI
  10.1016/j.jbc.2022.102444
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03207, KAKENHI-PROJECT-22KJ1502
[Journal Article] Structure-based design of UDP-GlcNAc analogs as candidate GnT-V inhibitors2022
- Author(s)
  Vibhute Amol M.、Tanaka Hide-nori、Mishra Sushil K.、Osuka Reina F.、Nagae Masamichi、Yonekawa Chizuko、Korekane Hiroaki、Doerksen Robert J.、Ando Hiromune、Kizuka Yasuhiko
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: 1866 Issue: 6 Pages: 130118-130118
- DOI
  10.1016/j.bbagen.2022.130118
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03207, KAKENHI-PROJECT-19F01098, KAKENHI-PROJECT-20K06575
[Journal Article] Metabolic utilization and remodeling of glycan biosynthesis using fucose analogs2022
- Author(s)
  Kizuka Yasuhiko
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: 1866 Issue: 12 Pages: 130243-130243
- DOI
  10.1016/j.bbagen.2022.130243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03207
[Journal Article] The stem region of α1,6-fucosyltransferase FUT8 is required for multimer formation but not catalytic activity2022
- Author(s)
  Tomida Seita、Nagae Masamichi、Kizuka Yasuhiko
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 298 Issue: 12 Pages: 102676-102676
- DOI
  10.1016/j.jbc.2022.102676
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03207, KAKENHI-PROJECT-22KJ1502, KAKENHI-PROJECT-20K06575
[Journal Article] Shedding of N-acetylglucosaminyltransferase-V is regulated by maturity of cellular N-glycan2022
- Author(s)
  Hirata Tetsuya、Takata Misaki、Tokoro Yuko、Nakano Miyako、Kizuka Yasuhiko
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 743-743
- DOI
  10.1038/s42003-022-03697-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03207
[Journal Article] Discovery of a lectin domain that regulates enzyme activity in mouse N-acetylglucosaminyltransferase-IVa (MGAT4A)2022
- Author(s)
  Nagae Masamichi、Hirata Tetsuya、Tateno Hiroaki、Mishra Sushil K.、Manabe Noriyoshi、Osada Naoko、Tokoro Yuko、Yamaguchi Yoshiki、Doerksen Robert J.、Shimizu Toshiyuki、Kizuka Yasuhiko
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 695-695
- DOI
  10.1038/s42003-022-03661-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06562, KAKENHI-PROJECT-20H03207, KAKENHI-PROJECT-20K06575
[Journal Article] Examination of differential glycoprotein preferences of N-acetylglucosaminyltransferase-IV isozymes a and b2022
- Author(s)
  Osada Naoko、Nagae Masamichi、Nakano Miyako、Hirata Tetsuya、Kizuka Yasuhiko
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 298 Issue: 9 Pages: 102400-102400
- DOI
  10.1016/j.jbc.2022.102400
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03207, KAKENHI-PROJECT-20K06575
[Journal Article] N-acetylglucosaminyltransferase-V requires a specific noncatalytic luminal domain for its activity toward glycoprotein substrates.2022
- Author(s)
  Osuka RF, Hirata T, Nagae M, Nakano M, Shibata H, Okamoto R, Kizuka Y.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 298 Issue: 3 Pages: 101666-101666
- DOI
  10.1016/j.jbc.2022.101666
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H02922, KAKENHI-PROJECT-20H03207, KAKENHI-PROJECT-20K06575
[Journal Article] Tissue-Specific Regulation of HNK-1 Biosynthesis by Bisecting GlcNAc2021
- Author(s)
  Kawade Haruka、Morise Jyoji、Mishra Sushil K.、Tsujioka Shuta、Oka Shogo、Kizuka Yasuhiko
- Journal Title
  
  Molecules
  
  Volume: 26 Issue: 17 Pages: 5176-5176
- DOI
  10.3390/molecules26175176
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03370, KAKENHI-PROJECT-20H03207
[Journal Article] Roles of protein arginine methyltransferase 1 (PRMT1) in brain development and disease2021
- Author(s)
  Hashimoto Misuzu、Fukamizu Akiyoshi、Nakagawa Tsutomu、Kizuka Yasuhiko
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: 1865 Issue: 1 Pages: 129776-129776
- DOI
  10.1016/j.bbagen.2020.129776
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15913, KAKENHI-PROJECT-17H01519, KAKENHI-PROJECT-20H03207
[Journal Article] Peptide Sequence Mapping around Bisecting GlcNAc-Bearing N-Glycans in Mouse Brain.2021
- Author(s)
  Ohkawa Y, Kizuka Y, Takata M, Nakano M, Ito E, Mishra SK, Akatsuka H, Harada Y, Taniguchi N.
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 22 Issue: 16 Pages: 8579-8579
- DOI
  10.3390/ijms22168579
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02922, KAKENHI-PROJECT-20H03207, KAKENHI-PROJECT-20K07629
[Journal Article] N-Glycosylation2021
- Author(s)
  Hirata Tetsuya、Kizuka Yasuhiko
- Journal Title
  
  Adv. Exp. Med. Biol.
  
  Volume: 1325 Pages: 3-24
- DOI
  10.1007/978-3-030-70115-4_1
- ISBN
  9783030701147, 9783030701154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03207
[Journal Article] 3D Structure and Function of Glycosyltransferases Involved in N-glycan Maturation2020
- Author(s)
  Nagae Masamichi、Yamaguchi Yoshiki、Taniguchi Naoyuki、Kizuka Yasuhiko
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 2 Pages: 437-437
- DOI
  10.3390/ijms21020437
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06290, KAKENHI-PROJECT-17K07303, KAKENHI-PROJECT-17K07356, KAKENHI-PROJECT-20K06575, KAKENHI-PROJECT-19H03362
[Journal Article] Recognition of glycan and protein substrates by N-acetylglucosaminyltransferase-V2020
- Author(s)
  Hirata Tetsuya、Nagae Masamichi、Osuka Reina F.、Mishra Sushil K.、Yamada Mayumi、Kizuka Yasuhiko
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: 1864 Issue: 12 Pages: 129726-129726
- DOI
  10.1016/j.bbagen.2020.129726
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06575, KAKENHI-PROJECT-20H03207
[Journal Article] Region-specific upregulation of HNK-1 glycan in the PRMT1-deficient brain2020
- Author(s)
  Hashimoto Misuzu、Hirata Tetsuya、Yonekawa Chizuko、Takeichi Kaho、Fukamizu Akiyoshi、Nakagawa Tsutomu、Kizuka Yasuhiko
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: 1864 Issue: 3 Pages: 129509-129509
- DOI
  10.1016/j.bbagen.2019.129509
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07356, KAKENHI-PROJECT-17H01519
[Journal Article] Differential Labeling of Glycoproteins with Alkynyl Fucose Analogs2020
- Author(s)
  Ma Chenyu、Takeuchi Hideyuki、Hao Huilin、Yonekawa Chizuko、Nakajima Kazuki、Nagae Masamichi、Okajima Tetsuya、Haltiwanger Robert S.、Kizuka Yasuhiko
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 17 Pages: 6007-6007
- DOI
  10.3390/ijms21176007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06575, KAKENHI-PROJECT-19K22490, KAKENHI-PROJECT-19KK0195, KAKENHI-PROJECT-19H03416, KAKENHI-PROJECT-19H03176, KAKENHI-PROJECT-20H03207
[Journal Article] The SH3 domain in the fucosyltransferase FUT8 controls FUT8 activity and localization and is essential for core fucosylation2020
- Author(s)
  Tomida Seita、Takata Misaki、Hirata Tetsuya、Nagae Masamichi、Nakano Miyako、Kizuka Yasuhiko
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 295 Issue: 23 Pages: 7992-8004
- DOI
  10.1074/jbc.ra120.013079
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06575, KAKENHI-PROJECT-19H02922, KAKENHI-PROJECT-18K06115, KAKENHI-PROJECT-20H03207
[Journal Article] Generation of the heterogeneity of extracellular vesicles by membrane organization and sorting machineries2019
- Author(s)
  Harada Yoichiro、Suzuki Takehiro、Fukushige Tomoko、Kizuka Yasuhiko、Yagi Hirokazu、Yamamoto Mika、Kondo Kiyotaka、Inoue Hiromasa、Kato Koichi、Taniguchi Naoyuki、Kanekura Takuro、Dohmae Naoshi、Maruyama Ikuro
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: 1863 Issue: 4 Pages: 681-691
- DOI
  10.1016/j.bbagen.2019.01.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07356, KAKENHI-PROJECT-18K06914, KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-15K14481, KAKENHI-PROJECT-15H04700, KAKENHI-PROJECT-17H03926, KAKENHI-PROJECT-16K10746, KAKENHI-PROJECT-18K19587
[Journal Article] N‐glycome inheritance from cells to extracellular vesicles in B16 melanomas2019
- Author(s)
  Harada Yoichiro、Kizuka Yasuhiko、Tokoro Yuko、Kondo Kiyotaka、Yagi Hirokazu、Kato Koichi、Inoue Hiromasa、Taniguchi Naoyuki、Maruyama Ikuro
- Journal Title
  
  FEBS Letters
  
  Volume: 印刷中 Issue: 9 Pages: 942-951
- DOI
  10.1002/1873-3468.13377
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07356, KAKENHI-PROJECT-17H03926, KAKENHI-PROJECT-16K10746, KAKENHI-PROJECT-18K19587
[Journal Article] Bisecting GlcNAc Is a General Suppressor of Terminal Modification of N-glycan2019
- Author(s)
  Nakano M, Mishra SK, Tokoro Y, Sato K, Nakajima K, Yamaguchi Y, Taniguchi N, Kizuka Y.
- Journal Title
  
  Mol Cell Proteomics
  
  Volume: 18(10) Issue: 10 Pages: 2044-2057
- DOI
  10.1074/mcp.ra119.001534
- NAID
  120006731226
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06115, KAKENHI-PROJECT-18K08257, KAKENHI-PROJECT-16H06290, KAKENHI-PROJECT-19H02922, KAKENHI-PROJECT-17K07356, KAKENHI-PROJECT-19H03362
[Journal Article] Detection and Modulation of Fucosylated Glycans using Fucose Analogs2019
- Author(s)
  Kizuka Yasuhiko
- Journal Title
  
  Trends in Glycoscience and Glycotechnology
  
  Volume: 31 Issue: 178 Pages: E1-E6
- DOI
  10.4052/tigg.1757.1E
- NAID
  130007556939
- ISSN
  0915-7352, 1883-2113
- Year and Date
  2019-01-25
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07356
[Journal Article] Regulated Expression and Disease Relevance of Neural Glycans2019
- Author(s)
  Kizuka Yasuhiko
- Journal Title
  
  Trends in Glycoscience and Glycotechnology
  
  Volume: 31 Issue: 181 Pages: SE89-SE90
- DOI
  10.4052/tigg.1942.2SE
- NAID
  130007683613
- ISSN
  0915-7352, 1883-2113
- Year and Date
  2019-07-25
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07356
[Journal Article] Identification and characterization of UDP-mannose in human cell lines and mouse organs: Differential distribution across brain regions and organs2018
- Author(s)
  Nakajima Kazuki、Kizuka Yasuhiko、Yamaguchi Yoshiki、Hirabayashi Yoshio、Takahashi Kazuo、Yuzawa Yukio、Taniguchi Naoyuki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 495 Issue: 1 Pages: 401-407
- DOI
  10.1016/j.bbrc.2017.10.173
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14481, KAKENHI-PROJECT-18K06914, KAKENHI-PROJECT-16H06290, KAKENHI-PROJECT-16K09632, KAKENHI-PROJECT-15H04700, KAKENHI-PROJECT-16H04758
[Journal Article] 1.Imamaki R. Ogawa K, Kizuka Y, Komi Y, Kojima S, Kotani N, Honke K, Honda T, Taniguchi N, and Kitazume S2018
- Author(s)
  1.Imamaki R. Ogawa K, Kizuka Y, Komi Y, Kojima S, Kotani N, Honke K, Honda T, Taniguchi N, and Kitazume S
- Journal Title
  
  Oncogene
  
  Volume: - Issue: 31 Pages: 4287-4299
- DOI
  10.1038/s41388-018-0271-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08601, KAKENHI-PROJECT-18K06914, KAKENHI-WRAPUP-18H05199, KAKENHI-PROJECT-16K08591, KAKENHI-PROJECT-15K14481, KAKENHI-PROJECT-15H04700
[Journal Article] Structure and mechanism of cancer-associated N-acetylglucosaminyltransferase-V2018
- Author(s)
  Nagae Masamichi、Kizuka Yasuhiko、Mihara Emiko、Kitago Yu、Hanashima Shinya、Ito Yukishige、Takagi Junichi、Taniguchi Naoyuki、Yamaguchi Yoshiki
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 3380-3380
- DOI
  10.1038/s41467-018-05931-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07303, KAKENHI-PROJECT-17K07356, KAKENHI-PROJECT-18K06914, KAKENHI-PROJECT-18K19298, KAKENHI-PROJECT-16H06290, KAKENHI-PROJECT-17H01420, KAKENHI-PROJECT-15K14481, KAKENHI-PROJECT-15H04700, KAKENHI-PROJECT-16H04758
[Journal Article] Neural functions of bisecting GlcNAc.2018
- Author(s)
  Kizuka Y, Taniguchi N
- Journal Title
  
  Glycoconj. J.
  
  Volume: ー Issue: 4 Pages: 345-351
- DOI
  10.1007/s10719-018-9829-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06914, KAKENHI-PROJECT-15K14481, KAKENHI-PROJECT-15H04700
[Journal Article] High affinity sugar ligands of C-type lectin receptor langerin.2018
- Author(s)
  Ota F, Hirayama T, Kizuka Y, Yamaguchi Y, Fujinawa R, Nagata M; Ismanto HS, Lepenies, Aretz J, Rademacher C, Seeberger PH; Angata T, Kitazume S, Yoshida K, Betsuyaku T, Kida K Yamasaki S, and Taniguchi N
- Journal Title
  
  BBA - General Subjects
  
  Volume: - Issue: 7 Pages: 1592-1601
- DOI
  10.1016/j.bbagen.2018.04.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08601, KAKENHI-PROJECT-17K07356, KAKENHI-PROJECT-18K06914, KAKENHI-PLANNED-26110009, KAKENHI-PROJECT-15K14481, KAKENHI-PROJECT-15H04700, KAKENHI-PROJECT-16H04758, KAKENHI-PROJECT-17H04087
[Journal Article] Implication of C-type lectin receptor langerin and keratan sulfate disaccharide in emphysema2018
- Author(s)
  Kizuka Yasuhiko、Mishra Sushil、Yamaguchi Yoshiki、Taniguchi Naoyuki
- Journal Title
  
  Cellular Immunology
  
  Volume: 333 Pages: 80-84
- DOI
  10.1016/j.cellimm.2018.07.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07356, KAKENHI-PROJECT-18K06914, KAKENHI-PROJECT-15K14481, KAKENHI-PROJECT-15H04700, KAKENHI-PROJECT-16H04758
[Journal Article] An Alkynyl-Fucose Halts Hepatoma Cell Migration and Invasion by Inhibiting GDP-Fucose-Synthesizing Enzyme FX, TSTA32017
- Author(s)
  Kizuka Yasuhiko、Nakano Miyako、Yamaguchi Yoshiki、Nakajima Kazuki、Oka Ritsuko、Sato Keiko、Ren Chien-Tai、Hsu Tsui-Ling、Wong Chi-Huey、Taniguchi Naoyuki
- Journal Title
  
  Cell Chemical Biology
  
  Volume: 24 Issue: 12 Pages: 1467-1478
- DOI
  10.1016/j.chembiol.2017.08.023
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07356, KAKENHI-PROJECT-15H04700, KAKENHI-PROJECT-16H04758
[Journal Article] N -glycan and Alzheimer's disease2017
- Author(s)
  Kizuka Yasuhiko、Kitazume Shinobu、Taniguchi Naoyuki
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: 1861 Issue: 10 Pages: 2447-2454
- DOI
  10.1016/j.bbagen.2017.04.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07356, KAKENHI-PROJECT-15K14481
[Journal Article] Expression of Neural Glycans and Their Role in Disease2017
- Author(s)
  Kizuka Y.
- Journal Title
  
  Trends in Glycoscience and Glycotechnology
  
  Volume: 29 Issue: 165 Pages: E11-E18
- DOI
  10.4052/tigg.1613.2E
- NAID
  130005297139
- ISSN
  0915-7352, 1883-2113
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670148
[Journal Article] Sialylation of extracellular superoxide dismutase (EC-SOD) enhances furin-mediated cleavage and secretion2017
- Author(s)
  Ota Fumi、Kizuka Yasuhiko、Nakano Miyako、Yamaguchi Yoshiki、Kitazume Shinobu、Ookawara Tomomi、Taniguchi Naoyuki
- Journal Title
  
  Glycobiology
  
  Volume: 27 Issue: 12 Pages: 1081-1088
- DOI
  10.1093/glycob/cwx087
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07356, KAKENHI-PROJECT-15K14481, KAKENHI-PROJECT-15H04700, KAKENHI-PROJECT-16H04758
[Journal Article] Epigenetic regulation of neural N-glycomics.2016
- Author(s)
  Kizuka Y, Nakano M, Miura Y, Taniguchi N.
- Journal Title
  
  Proteomics
  
  Volume: 16 Issue: 22 Pages: 2854-2863
- DOI
  10.1002/pmic.201600053
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04700, KAKENHI-PROJECT-26670148
[Journal Article] Enzymes for N-Glycan Branching and Their Genetic and Nongenetic Regulation in Cancer.2016
- Author(s)
  Kizuka Y, Taniguchi N.
- Journal Title
  
  Biomolecules
  
  Volume: 6 Issue: 2 Pages: 25-25
- DOI
  10.3390/biom6020025
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04700, KAKENHI-PROJECT-26670148
[Journal Article] Disease-associated glycans on cell surface proteins.2016
- Author(s)
  Takahashi M, Kizuka Y, Ohtsubo K, Gu J, Taniguchi N.
- Journal Title
  
  Molecular Aspects of Medicine
  
  Volume: 51 Pages: 56-70
- DOI
  10.1016/j.mam.2016.04.008
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04700, KAKENHI-PROJECT-26430118, KAKENHI-PROJECT-26440058, KAKENHI-PROJECT-15K14408, KAKENHI-PROJECT-26670148
[Journal Article] Bisecting GlcNAc modification stabilizes BACE1 protein under oxidative stress conditions2016
- Author(s)
  Kizuka Y, Nakano M, Kitazume S, Saito T, Saido TC, Taniguchi N
- Journal Title
  
  Biochemical Journal
  
  Volume: 473 Issue: 1 Pages: 21-30
- DOI
  10.1042/bj20150607
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K14481, KAKENHI-PROJECT-26670148, KAKENHI-PUBLICLY-26110723, KAKENHI-PUBLICLY-26117522, KAKENHI-PROJECT-15H04700, KAKENHI-PROJECT-25430122, KAKENHI-PROJECT-26290019
[Journal Article] High-Sensitivity and Low-Toxicity Fucose Probe for Glycan Imaging and Biomarker Discovery.2016
- Author(s)
  Kizuka Y, Funayama S, Shogomori H, Nakano M, Nakajima K, Oka R, Kitazume S, Yamaguchi Y, Sano M, Korekane H, Hsu TL, Lee HY, Wong CH, Taniguchi N.
- Journal Title
  
  Cell Chemical Biology
  
  Volume: 23 Issue: 7 Pages: 782-792
- DOI
  10.1016/j.chembiol.2016.06.010
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04700, KAKENHI-PROJECT-26670148, KAKENHI-PROJECT-15K19016, KAKENHI-PROJECT-16K07998, KAKENHI-PROJECT-16H04758
[Journal Article] Clec4g (LSECtin) interacts with BACE1 and suppresses Aβ generation2015
- Author(s)
  Kizuka Y, Kitazume S, Sato K, Taniguchi N
- Journal Title
  
  FEBS Letters
  
  Volume: 589 Issue: 13 Pages: 1418-1422
- DOI
  10.1016/j.febslet.2015.04.060
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K14481, KAKENHI-PROJECT-26670148, KAKENHI-PUBLICLY-26117522, KAKENHI-PROJECT-15H04700, KAKENHI-PROJECT-25430122
[Journal Article] Role of N-glycans in cancer biomarker, progression and metastasis and therapeutics2015
- Author(s)
  Naoyuki Taniguchi, Yasuhiko Kizuka
- Journal Title
  
  Advances in Cancer Research
  
  Volume: 126 Pages: 11-51
- DOI
  10.1016/bs.acr.2014.11.001
- Data Source
  KAKENHI-PROJECT-26670148
[Journal Article] Epigenetic regulation of a brain-specific glycosyltransferase N-acetylglucosaminyltransferase-IX (GnT-IX) by specific chromatin modifiers2014
- Author(s)
  Kizuka Y, Kitazume S, Okahara K, Villagra A, Sotomayor EM, Taniguchi N
- Journal Title
  
  J Biol Chem. (Epub 2014 Mar10.)
  
  Volume: 289(16) Issue: 16 Pages: 11253-61
- DOI
  10.1074/jbc.m114.554311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249018, KAKENHI-PROJECT-23770163
[Journal Article] Regulated expression and neural functions of human natural killer-1 (HNK-1) carbohydrate.2012
- Author(s)
  Y. Kizuka and S. Oka.
- Journal Title
  
  Cell Mol. Life Sci
  
  Volume: 69(24) Issue: 24 Pages: 4135-47
- DOI
  10.1007/s00018-012-1036-z
- NAID
  120005122349
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659153, KAKENHI-PROJECT-23770163, KAKENHI-PLANNED-23110006
[Journal Article] エピゲノムによる糖鎖生合成遺伝子GnT-IXの脳特異的な発現制御機構2012
- Author(s)
  木塚康彦、北爪しのぶ、谷口直之
- Journal Title
  
  THE LUNG perspectives
  
  Volume: 20 Pages: 75-80
- Data Source
  KAKENHI-PROJECT-23770163
[Journal Article] Brain-specific expression of N-acetylglucosaminyltransferase IX (GnT-IX) is regulated by epigenetic histone modifications2011
- Author(s)
  Y.Kizuka, S.Kitazume, M.Yoshida, N.Taniguchi
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 286 Issue: 36 Pages: 31875-31884
- DOI
  10.1074/jbc.m111.251173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570154, KAKENHI-PROJECT-23770163
[Presentation] First total synthesis of ganglioside SJG-2 and evaluation of its neurite outgrowth activity2023
- Author(s)
  Naoko KOMURA, Hiroyuki MANO , Yuta HASHIMOTO, Koichi SAKAMOTO, Hide-Nori TANAKA, Akihiro IMAMURA, Hideharu ISHIDA, Yasuhiko KIZUKA, Hiromune ANDO
- Organizer
  The 21st European Carbohydrate Symposium in Paris (Eurocarb21)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00359
[Presentation] Protein selective actions of N-glycan branching enzymes2022
- Author(s)
  Kizuka Y.
- Organizer
  UGLIP Seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03207
[Presentation] 糖転移酵素のタンパク質選択性を標的としたGlycoscience2022
- Author(s)
  木塚康彦
- Organizer
  第41回日本糖質学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03207
[Presentation] ゴルジ体におけるN型糖鎖の成熟過程を制御する小胞体2022
- Author(s)
  木塚康彦
- Organizer
  第45回日本分子学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03207
[Presentation] Insights into protein-selective action of GnT-V2021
- Author(s)
  4. Kizuka Y.
- Organizer
  The 3rd Australasian Glycoscience Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03207
[Presentation] がん関連糖転移酵素GnT-Vの発現制御と標的選択のメカニズム2021
- Author(s)
  木塚康彦
- Organizer
  第94回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03207
[Presentation] N型糖鎖の枝分かれの生化学2021
- Author(s)
  木塚康彦
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03207
[Presentation] SH3 domain of FUT8 is required for its enzymatic activity, cell surface localization and association with ribophorin l2020
- Author(s)
  Kizuka Y.
- Organizer
  Annual Meeting of the Society for Glycobiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03207
[Presentation] 糖タンパク質のbisecting GlcNAc糖鎖修飾の生理機能と認知症との関わり2019
- Author(s)
  木塚康彦
- Organizer
  第83回生化学会中部支部例会
- Data Source
  KAKENHI-PROJECT-17K07356
[Presentation] Bisecting GlcNAc is a general suppressor of terminal modifications of N-glycans2019
- Author(s)
  Yasuhiko Kizuka
- Organizer
  XXV International Symposium on Glycoconjugates
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07356
[Presentation] Suppression of terminal N-glycan modifications by bisecting GlcNAc2019
- Author(s)
  Yasuhiko Kizuka
- Organizer
  Annual Meeting of the Society for Glycobiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07356
[Presentation] Biosynthetic regulation of Complex N-glycan structures2019
- Author(s)
  Yasuhiko Kizuka
- Organizer
  International Symposium on Bio-CHAINs
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07356
[Presentation] N型糖鎖の枝分かれ構造の生合成と疾患との関連性2018
- Author(s)
  木塚康彦
- Organizer
  第3回名大医薬系3部局交流シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17K07356
[Presentation] 糖アナログを利用した糖鎖機能の追跡と改変2018
- Author(s)
  木塚康彦
- Organizer
  第70回日本生物工学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K07356
[Presentation] 糖鎖生物学を研究する上でのデータベースへの期待2018
- Author(s)
  木塚康彦
- Organizer
  トーゴーの日シンポジウム2018
- Invited
- Data Source
  KAKENHI-PROJECT-17K07356
[Presentation] がん・アルツハイマー病に関与する糖転移酵素の構造と機能2018
- Author(s)
  木塚康彦
- Organizer
  第8回岐阜構造生物学・医学・論理的創薬シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17K07356
[Presentation] 糖鎖の枝分かれ構造の生化学2018
- Author(s)
  木塚康彦
- Organizer
  日本農芸化学会中部支部第184回例会若手シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17K07356
[Presentation] Inhibitory roles of bisecting GlcNAc in terminal modifications of N-glycan2018
- Author(s)
  Kizuka Y., Nakano M., Taniguchi N
- Organizer
  The 11th International Symposium on Glycosyltransferases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07356
[Presentation] 糖アナログを用いた糖鎖機能の追跡と改変2018
- Author(s)
  木塚康彦
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K07356
[Presentation] Regulation of terminal N-glycan modifications by bisecting GlcNAc2018
- Author(s)
  Kizuka Y., Nakano M., Taniguchi N
- Organizer
  Annual Meeting of the Society for Glycobiology. 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07356
[Presentation] 神経系糖鎖の発現・機能解析とケミカルツールの開発2017
- Author(s)
  木塚康彦
- Organizer
  ConBIO2017
- Invited
- Data Source
  KAKENHI-PROJECT-17K07356
[Presentation] Bisecting GlcNAcが持つN型糖鎖末端の修飾抑制機能2017
- Author(s)
  木塚康彦、中の三弥子、北爪しのぶ、谷口直之
- Organizer
  第36回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-17K07356
[Presentation] N型糖鎖のbisecting GlcNAc修飾に関する研究2017
- Author(s)
  木塚康彦
- Organizer
  糖鎖科学中部拠点第14回若手の力フォーラム
- Data Source
  KAKENHI-PROJECT-17K07356
[Presentation] Glyco-chemical biology using fucose analogs2017
- Author(s)
  Kizuka Y., Funayama S., Nakano M., Nakajima K., Yamaguchi Y., Kitazume S., Ren ST., Hsu TL., Wong CH., Taniguchi N
- Organizer
  XXIV International Symposium on Glycoconjugates
- Data Source
  KAKENHI-PROJECT-17K07356
[Presentation] アルツハイマー病におけるbisecting GlcNAc糖鎖の役割について2017
- Author(s)
  木塚康彦
- Organizer
  新学術領域「神経糖鎖生物学」最終シンポジウム
- Place of Presentation
  JPタワー（名古屋）
- Year and Date
  2017-03-03
- Invited
- Data Source
  KAKENHI-PROJECT-26670148
[Presentation] Detection and disease involvement of bisecting GlcNAc and fucosylated glycans2017
- Author(s)
  Yasuhiko Kizuka
- Organizer
  Internaltional Symposium, Systems Glycobiology and Beyond
- Invited
- Data Source
  KAKENHI-PROJECT-17K07356
[Presentation] Suppressive effects of bisecting GlcNAc on terminal modifications of N-glycans2017
- Author(s)
  Kizuka Y., Nakano M., Taniguchi N
- Organizer
  Annual Meeting of the Society for Glycobiology
- Data Source
  KAKENHI-PROJECT-17K07356
[Presentation] フコース誘導体を用いたグライコケミカルバイオロジー2017
- Author(s)
  木塚康彦、谷口直之
- Organizer
  ConBIO2017
- Invited
- Data Source
  KAKENHI-PROJECT-17K07356
[Presentation] 神経系における糖鎖修飾とアルツハイマー病2017
- Author(s)
  木塚康彦
- Organizer
  第13回レドックス・ライフイノベーションシンポジウム
- Place of Presentation
  奈良女子大学（奈良）
- Year and Date
  2017-03-16
- Invited
- Data Source
  KAKENHI-PROJECT-26670148
[Presentation] Glyco-redox, a link of glycobiology and redox balance, is implicated in Alzheimer’s disease2016
- Author(s)
  Kizuka Y., Chienwichai P., Taniguchi N
- Organizer
  The 9th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
- Place of Presentation
  仙台国際センター（仙台）
- Year and Date
  2016-05-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670148
[Presentation] Physiological and pathological roles of bisecting GlcNAc2016
- Author(s)
  Kizuka Y., Nakano M., Kitazume S., Taniguchi N.
- Organizer
  RIKEN-Max Planck Joint Research Center for Systems Chemical Biology, The fifth symposium
- Place of Presentation
  ベルリン（ドイツ）
- Year and Date
  2016-04-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670148
[Presentation] アルツハイマー病を促進させるバイセクト糖鎖2016
- Author(s)
  木塚康彦、北爪しのぶ、谷口直之
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2016-03-09
- Invited
- Data Source
  KAKENHI-PUBLICLY-26110723
[Presentation] Epigenetic regulation of glycosyltransferase2016
- Author(s)
  Kizuka Y, Nakano M, Taniguchi N
- Organizer
  The 3rd International Symposium on Glyco-Neuroscience
- Place of Presentation
  淡路夢舞台国際会議場(淡路)
- Year and Date
  2016-01-14
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26110723
[Presentation] アルツハイマー病を促進させるバイセクト糖鎖2016
- Author(s)
  木塚康彦、北爪しのぶ、谷口直之
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Invited
- Data Source
  KAKENHI-PROJECT-26670148
[Presentation] Bisecting GlcNAc糖鎖修飾とアルツハイマー病に関する研究2016
- Author(s)
  木塚康彦、北爪しのぶ、谷口直之
- Organizer
  第57回日本生化学会中国・四国支部例会
- Place of Presentation
  高知大学（高知）
- Year and Date
  2016-05-27
- Invited
- Data Source
  KAKENHI-PROJECT-26670148
[Presentation] Bisecting GlcNAc regulates Alzheimer’s Disease development2015
- Author(s)
  Kizuka Y, Kitazume S, Nakano M, Saido T, Yamaguchi Y, Yoshida M, Hashimoto Y, Endo T, Taniguchi N
- Organizer
  4th Austria-Japan Seminar for Comparative and Developmental Glycobiology
- Place of Presentation
  Split (Croatia)
- Year and Date
  2015-09-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670148
[Presentation] BACE1のbisecting GlcNAc修飾によるアルツハイマー病の発症メカニズム2015
- Author(s)
  木塚康彦、北爪しのぶ、中の三弥子、西道隆臣、橋本康弘、遠藤玉夫、谷口直之
- Organizer
  第88回日本生化学会大会第38回日本分子生物学会年会合同大会
- Place of Presentation
  神戸ポートアイランド(神戸)
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PUBLICLY-26110723
[Presentation] Bisecting GlcNAcは酸化ストレスによるBACE1の発現誘導を制御する2015
- Author(s)
  木塚康彦、北爪しのぶ、谷口直之
- Organizer
  第2回FCCAシンポジウムFCCAグライコサイエンス若手フォーラム2015
- Place of Presentation
  東京
- Year and Date
  2015-07-30
- Data Source
  KAKENHI-PROJECT-26670148
[Presentation] BACE1のbisecting GlcNAc修飾によるアルツハイマー病の発症メカニズム2015
- Author(s)
  木塚康彦、北爪しのぶ、中の三弥子、西道隆臣、橋本康弘、遠藤玉夫、谷口直之
- Organizer
  第88回日本生化学会大会第38回日本分子生物学会年会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-26670148
[Presentation] Bisecting GlcNAcによるBACE1の分解制御メカニズム2015
- Author(s)
  木塚康彦、中の三弥子、北爪しのぶ、斉藤貴志、西道隆臣、谷口直之
- Organizer
  GlycoTOKYO2015シンポジウム
- Place of Presentation
  東京
- Year and Date
  2015-10-24
- Data Source
  KAKENHI-PROJECT-26670148
[Presentation] 神経系糖鎖の発現制御と認知症病態形成における役割についての研究2015
- Author(s)
  木塚康彦
- Organizer
  第34回日本糖質学会年会
- Place of Presentation
  東京大学(東京)
- Year and Date
  2015-07-31
- Invited
- Data Source
  KAKENHI-PUBLICLY-26110723
[Presentation] Bisecting GlcNAcによるBACE1の分解制御メカニズム2015
- Author(s)
  木塚康彦、中の三弥子、北爪しのぶ、斉藤貴志、西道隆臣、谷口直之
- Organizer
  GlycoTOKYO2015シンポジウム
- Place of Presentation
  慶応義塾大学(東京)
- Year and Date
  2015-10-24
- Data Source
  KAKENHI-PUBLICLY-26110723
[Presentation] Bisecting GlcNAc on BACE1 is a Novel Therapeutic Target for Alzheimer’s Disease2015
- Author(s)
  Kizuka Y, Kitazume S, Nakano M, Saido T, Hashimoto Y, Endo T, Taniguchi N
- Organizer
  XXIII International Symposium on Glycoconjugates.
- Place of Presentation
  Split (Croatia)
- Year and Date
  2015-09-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670148
[Presentation] 神経系糖鎖の発現制御と認知症病態形成における役割についての研究2015
- Author(s)
  木塚康彦
- Organizer
  第34回日本糖質学会年会
- Place of Presentation
  東京
- Year and Date
  2015-07-31
- Invited
- Data Source
  KAKENHI-PROJECT-26670148
[Presentation] Bisecting GlcNAc regulates Alzheimer’s Disease development2015
- Author(s)
  Kizuka Y, Kitazume S, Nakano M, Saido T, Yamaguchi Y, Yoshida M, Hashimoto Y, Endo T, Taniguchi N
- Organizer
  4th Austria-Japan Seminar for Comparative and Developmental Glycobiology
- Place of Presentation
  Split (Croatia)
- Year and Date
  2015-09-15
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26110723
[Presentation] Bisecting GlcNAc modification is a novel therapeutic target for Alzheimer’s disease2015
- Author(s)
  Kizuka Y, Kitazume S, Saido T, Nakano M, Ohnuki T, Shirouzu M, Yoshida M, Zegzouti H, Endo T, Taniguchi N
- Organizer
  RIKEN-Max Planck Joint Research Center for Systems Chemical Biology, The 4th symposium
- Place of Presentation
  神戸ポートアイランドセンター(神戸)
- Year and Date
  2015-05-11
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26110723
[Presentation] Bisecting GlcNAc modification is a novel therapeutic target for Alzheimer’s disease2015
- Author(s)
  Kizuka Y, Kitazume S, Saido T, Nakano M, Ohnuki T, Shirouzu M, Yoshida M, Zegzouti H, Endo T, Taniguchi N
- Organizer
  RIKEN-Max Planck Joint Research Center for Systems Chemical Biology, The 4th symposium
- Place of Presentation
  神戸
- Year and Date
  2015-05-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670148
[Presentation] Bisecting GlcNAcは酸化ストレスによるBACE1の発現誘導を制御する2015
- Author(s)
  木塚康彦、北爪しのぶ、谷口直之
- Organizer
  第2回FCCAシンポジウムFCCAグライコサイエンス若手フォーラム2015
- Place of Presentation
  お茶ノ水女子大学(東京)
- Year and Date
  2015-07-30
- Data Source
  KAKENHI-PUBLICLY-26110723
[Presentation] Bisecting GlcNAc on BACE1 is a Novel Therapeutic Target for Alzheimer’s Disease2015
- Author(s)
  Kizuka Y, Kitazume S, Nakano M, Saido T, Hashimoto Y, Endo T, Taniguchi N
- Organizer
  XXIII International Symposium on Glycoconjugates
- Place of Presentation
  Split (Croatia)
- Year and Date
  2015-09-15
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26110723
[Presentation] 糖転移酵素のエピジェネティクス制御2014
- Author(s)
  木塚康彦、北爪しのぶ、谷口直之
- Organizer
  87回日本生化学会大会
- Place of Presentation
  京都（国際会館）
- Year and Date
  2014-10-16
- Data Source
  KAKENHI-PUBLICLY-26110723
[Presentation] 新規エピゲノム因子による脳特異的糖転移酵素GnT-IXの遺伝子発現制御.2013
- Author(s)
  木塚康彦,北爪しのぶ,谷口直之
- Organizer
  GlycoTOKYO2013シンポジウム.
- Place of Presentation
  成蹊大学(東京)
- Year and Date
  2013-10-19
- Data Source
  KAKENHI-PROJECT-23770163
[Presentation] Epigenetic regulation of glycosyltransferase gene expression.2013
- Author(s)
  Yasuhiko Kizuka, Shinobu Kitazume, Naoyuki Taniguchi.
- Organizer
  XXII International Symposium on Glybobonjugates.
- Place of Presentation
  Dalian(China)
- Year and Date
  2013-06-24
- Data Source
  KAKENHI-PROJECT-23770163
[Presentation] Gene expression of glycosyltransferase is regulated by selective epigenetic factors.2013
- Author(s)
  木塚康彦、北爪しのぶ、谷口直之
- Organizer
  RIKEN-Max Planck Joint Research Center for Systems Chemical Biology, The second symposium.
- Place of Presentation
  理化学研究所(和光)
- Year and Date
  2013-04-17
- Data Source
  KAKENHI-PROJECT-23770163
[Presentation] 脳特異的糖転移酵素GnT-IXの遺伝子発現を制御する新規エピゲノム因子の探索.2013
- Author(s)
  木塚康彦,北爪しのぶ,谷口直之
- Organizer
  第32回日本糖質学会年会.
- Place of Presentation
  大阪
- Year and Date
  2013-08-07
- Data Source
  KAKENHI-PROJECT-23770163
[Presentation] New epigenetic factors for brain-specific glycosyltransferase gene expression.2013
- Author(s)
  Yasuhiko Kizuka, Shinobu Kitazume, Naoyuki Taniguchi.
- Organizer
  The 3^<rd> Austria/Japan Seminar on Comparative and Developmental Glycobiology.
- Place of Presentation
  理化学研究所(和光)
- Year and Date
  2013-07-02
- Data Source
  KAKENHI-PROJECT-23770163
[Presentation] New epigenetic factors for brain-specific glycosyltransferase gene expression.2013
- Author(s)
  Yasuhiko Kizuka, Shinobu Kitazume, Naoyuki Taniguchi.
- Organizer
  2013 Society for Glycobiology Annual Meeting.
- Place of Presentation
  Tampa(USA).
- Year and Date
  2013-11-18
- Data Source
  KAKENHI-PROJECT-23770163
[Presentation] Brain specific regulation of GnT-IX expression by epigenetic mechanism2012
- Author(s)
  Yasuhiko Kizuka, Shinobu Kitazume, Minoru Yoshida, Naoyuki Taniguchi
- Organizer
  2nd RIKEN-SNU Symposium
- Place of Presentation
  Nami island
- Data Source
  KAKENHI-PROJECT-23770163
[Presentation] Brain specific regulation of GnT-IX expression by epigenetic mechanism2012
- Author(s)
  Yasuhiko Kizuka, Shinobu Kitazume, Minoru Yoshida, Naoyuki Taniguchi.
- Organizer
  2^<nd> RIKEN-SNU symposium.
- Place of Presentation
  Nami island (Korea)
- Data Source
  KAKENHI-PROJECT-23770163
[Presentation] エピジェネティクスによる脳特異的な糖転移酵素の発現制御メカニズム2012
- Author(s)
  木塚康彦、岡原京平、北爪しのぶ、谷口直之
- Organizer
  第31回日本糖質学会年会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-23770163
[Presentation] Gene expression of brain specific glycosyltransferases and their epigenetic regulation2012
- Author(s)
  Yasuhiko Kizuka, Kyohei Okahara, Shinobu Kitazume and Naoyuki Taniguchi
- Organizer
  Joint Meeting of the Society for Glycobiology and American Society for Matrix Biology
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-23770163
[Presentation] Gene expression of brain specific glycosyltransferases and their epigenetic regulation2012
- Author(s)
  Yasuhiko Kizuka, Kyohei Okahara, Shinobu Kitazume, Naoyuki Taniguchi.
- Organizer
  Joint Meeting of the Society for Glycobiology and American Society for Matrix Biology
- Place of Presentation
  San Diego(USA)
- Data Source
  KAKENHI-PROJECT-23770163
[Presentation] エピジェネティクスによる脳特異的な糖転移酵素の発現制御メカニズム.2012
- Author(s)
  木塚康彦、岡原京平、北爪しのぶ、谷口直之
- Organizer
  第31回日本糖質学会年会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-23770163
[Presentation] ヒストンコードにより制御されるGnT-IX遺伝子の脳特異的発現機構2011
- Author(s)
  木塚康彦、北爪しのぶ、吉田稔、谷口直之
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都府)
- Data Source
  KAKENHI-PROJECT-23770163
[Presentation] Regulation of brain-specific GnT-IX (Vb) expression by neural histone-code2011
- Author(s)
  Yasuhiko Kizuka, Shinobu Kitazume, Minoru Yoshida, Naoyuki Taniguchi.
- Organizer
  第31回内藤コンファレンス
- Place of Presentation
  シャトレーゼ・ガトーキングダムサッポロ(札幌)
- Year and Date
  2011-09-14
- Data Source
  KAKENHI-PROJECT-23770163
[Presentation] 脳特異的糖転移酵素GnT-IX遺伝子のエピジェネティックな発現制御2011
- Author(s)
  木塚康彦, 北爪しのぶ, 谷口直之
- Organizer
  GlycoTOKYO 2011 シンポジウム
- Place of Presentation
  理化学研究所(埼玉県)
- Data Source
  KAKENHI-PROJECT-23770163
[Presentation] Regulation of brain-specific GnT-IX (Vb) expression by neural histone-code2011
- Author(s)
  Yasuhiko Kizuka, Shinobu Kitazume, Minoru Yoshida, Naoyuki Taniguchi
- Organizer
  第31回内藤コンファレンス
- Place of Presentation
  シャトレーゼ・ガトーキングダムサッポロ（北海道）
- Data Source
  KAKENHI-PROJECT-23770163
[Presentation] 脳特異的糖転移酵素GnT-IX遺伝子のエピジェネティックな発現制御2011
- Author(s)
  木塚康彦,北爪しのぶ,谷口直之
- Organizer
  GlycoTOKYO 2011シンポジウム
- Place of Presentation
  理化学研究所(和光)
- Year and Date
  2011-12-09
- Data Source
  KAKENHI-PROJECT-23770163
[Presentation] Histone-code regulates brain specific expression of N-acetylglucosaminyltransferase-IX (GnT-IX)2011
- Author(s)
  Yasuhiko Kizuka, Shinobu Kitazume, Minoru Yoshida, Naoyuki Taniguchi
- Organizer
  Glyco21, 21st international symposium on glycoconjugates
- Place of Presentation
  ウィーン大学(オーストリア)
- Data Source
  KAKENHI-PROJECT-23770163
[Presentation] ヒストンコードにより制御されるGnT-IX遺伝子の脳特異的発現機構2011
- Author(s)
  木塚康彦、北爪しのぶ、吉田稔、谷口直之
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-23770163
[Presentation] Histone-code regulates brain specific expression of N-acetylglucosaminyltransferase-IX (GnT-IX)2011
- Author(s)
  Yasuhiko Kizuka, Shinobu Kitazume, Minoru Yoshida, Naoyuki Taniguchi.
- Organizer
  Glyco21, 21st international symposium on glycoconjugates
- Place of Presentation
  ウィーン大学(Austria)
- Year and Date
  2011-08-24
- Data Source
  KAKENHI-PROJECT-23770163
[Presentation] Epigenetic regulation of glycosyltransferase gene expression
- Author(s)
  木塚康彦、北爪しのぶ、谷口直之
- Organizer
  XXII International Symposium on Glycoconjugates
- Place of Presentation
  大連（中国）
- Data Source
  KAKENHI-PROJECT-23770163
[Presentation] Epigenetic regulation of glycosyltransferase
- Author(s)
  Yasuhiko Kizuka, Shinobu Kitazume, Taniguchi Naoyuki
- Organizer
  SFG & JSCR 2014 Joint Annual Meeting
- Place of Presentation
  USA, Hawaii, Honolulu (Hilton Hawaiian Village)
- Year and Date
  2014-11-16 – 2014-11-19
- Data Source
  KAKENHI-PUBLICLY-26110723
[Presentation] 脳特異的糖転移酵素GnT-IXの遺伝子発現を制御する新規エピゲノム因子の探索
- Author(s)
  木塚康彦、北爪しのぶ、谷口直之
- Organizer
  第32回日本糖質学会年会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23770163
[Presentation] Gene expression of glycosyltransferase is regulated by selective epigenetic factors
- Author(s)
  木塚康彦、北爪しのぶ、谷口直之
- Organizer
  RIKEN-Max Planck Joint Research Center for Systems Chemical Biology, The second symposium
- Place of Presentation
  理化学研究所（和光）
- Data Source
  KAKENHI-PROJECT-23770163
[Presentation] New epigenetic factors for brain-specific glycosyltransferase gene expression
- Author(s)
  木塚康彦、北爪しのぶ、谷口直之
- Organizer
  The 3rd Austria/Japan Seminar on Comparative and Developmental Glycobiology
- Place of Presentation
  理化学研究所（和光）
- Data Source
  KAKENHI-PROJECT-23770163
[Presentation] New epigenetic factors for brain-specific glycosyltransferase gene expression
- Author(s)
  木塚康彦、北爪しのぶ、谷口直之
- Organizer
  2013 Society for Glycobiology Annual Meeting
- Place of Presentation
  タンパ（アメリカ）
- Data Source
  KAKENHI-PROJECT-23770163
[Presentation] Bisecting GlcNAc欠損によるアルツハイマー病抑制に関する研究
- Author(s)
  木塚康彦、北爪しのぶ、藤縄玲子、斎藤貴志、岩田修永、西道隆臣、中の三弥子、山口芳樹、橋本康弘、Matthias Staufenbiel、初田裕幸、村山繁雄、萬谷博、遠藤玉夫、谷口直之
- Organizer
  第33回日本糖質学会年会
- Place of Presentation
  名古屋
- Year and Date
  2014-08-10 – 2014-08-12
- Data Source
  KAKENHI-PROJECT-26670148
[Presentation] 新規エピゲノム因子による脳特異的糖転移酵素GnT-IXの遺伝子発現制御
- Author(s)
  木塚康彦、北爪しのぶ、谷口直之
- Organizer
  GlycoTOKYO2013シンポジウム
- Place of Presentation
  東京（成蹊大学
- Data Source
  KAKENHI-PROJECT-23770163
[Presentation] High-throughput screening of GnT-III inhibitors using UDP-Glo system to develop a novel drug candidate for Alzheimer’s disease
- Author(s)
  Yasuhiko Kizuka, Shinobu Kitazume, Keiko Sato, Tetsuo Ohnuki, Mutsuko Kukimoto-Niino, Mikako Shirouzu, Minoru Yoshida, Laurie Engel, Hicham Zegzouti, Naoyuki Taniguchi
- Organizer
  SFG & JSCR 2014 Joint Annual Meeting
- Place of Presentation
  Honolulu
- Year and Date
  2014-11-16 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-26670148

1. TANIGUCHI Naoyuki (90002188)

# of Collaborated Projects: 2 results

# of Collaborated Products: 22 results
2. NAKANO Miyako (40397724)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
3. NAKAJIMA Kazuki (10442998)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KITAZUME Shinobu (80301753)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 顧建国 (40260369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 鈴木史朗 (70437268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 石水毅 (30314355)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 安藤弘宗 (20372518)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 鈴木健一 (50423059)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 矢木宏和 (70565423)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 田中秀則 (20725064)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 長江雅倫 (60619873)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
13. SATO Keiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. MORISE Jyoji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 川口しのぶ

# of Collaborated Projects: 0 results

# of Collaborated Products: 14 results
16. 岡昌吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. 山口芳樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 橋本美涼

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 真鍋法義

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KIZUKA YASUHIKO 木塚 康彦

KIZUKA Yasuhiko 木塚 康彦

Research Projects

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Co-Researchers

Mechanisms of protein-selective glycosylation regulated by unique domains of N-glycan branching enzymesPrincipal Investigator

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Molecular basis of feruloylarabinoxylan biosynthetic engineering

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An extedned research of cell membrane domains based on the probes of membrane molecules

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Mechanisms of cancer and Alzheimer's disease involving glycan branchingPrincipal Investigator

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Modulation of cancer cells by core fucose-specific antibody

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Mechanisms of expression and action of neurodegeneration-promoting glycan bisecting GlcNAcPrincipal Investigator

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神経系の糖鎖発現を規定するエピゲノム因子の探索Principal Investigator

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A novel trafficking mechanism regulated by bisecting GlcNAc, an Alzheimer's disease acceleratorPrincipal Investigator

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Epigenetic regulation of brain-specific O-mannose glycansPrincipal Investigator

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[Book] 生化学2015

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[Book] Epigenetic Regulation of and by Glycosylation (Glycoscience: Biology and Medicine)2014

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[Journal Article] N-acetylglucosaminyltransferase-V (GnT-V)-enriched small extracellular vesicles mediate N-glycan remodeling in recipient cells2023

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[Journal Article] ER entry pathway and glycosylation of GPI-anchored proteins are determined by N-terminal signal sequence and C-terminal GPI-attachment sequence2022

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[Journal Article] Structure-based design of UDP-GlcNAc analogs as candidate GnT-V inhibitors2022

Author(s)

KIZUKA YASUHIKO 木塚康彦

KIZUKA Yasuhiko 木塚康彦