Hamada Michito 濱田理人

… Alternative Names

濱田理人ハマダミチト

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Researcher Number	20567630
Other IDs
Affiliation (Current)	2025: 茨城県立医療大学, 保健医療学部, 教授
Affiliation (based on the past Project Information) *help	2023: 筑波大学, 医学医療系, 准教授 2021: 筑波大学, 医学医療系, 准教授 2013 – 2020: 筑波大学, 医学医療系, 助教
Review Section/Research Field	Principal Investigator Basic Section 42030:Animal life science-related / Basic Section 49030:Experimental pathology-related / Laboratory animal science / General medical chemistry Except Principal Investigator Basic Section 49010:Pathological biochemistry-related / Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Pathological medical chemistry
Keywords	Principal Investigator マクロファージ / MafB / MAFB / macrophage / 脾臓 / 交感神経 / Sympathetic nerve / Metabolism / adipose tissue / 恒常性維持 … More / 恒常性 / TAM / 腫瘍 / 悪性腫瘍 / 転写因子 / 腫瘍随伴マクロファージ / アポトーシス / 自己免疫疾患 / C1q … More Except Principal Investigator 線維化 / マクロファージ / 制御性単球 / Ym1 / 非アルコール性脂肪肝炎 / 肝臓 / 分化 / 長鎖脂肪酸 / 肝線維症 / 単球 / EGR2 / 代謝障害関連脂肪肝炎 / MASH / 近赤外蛍光 / 遺伝子改変マウス / 慢性炎症 / V型コラーゲン / iRFP / 近赤外光 / in vivoイメージング / リサーチバイオリソース / 炎症 / 腸炎 / 大腸炎 / CD169 / 細胞死 / 腸管免疫 / hnRNP / ビメンチン / DAMPs / 死細胞 / 炎症性腸疾患 / CCL8 Less

転写因子MAFBは脂肪組織マクロファージにおいて交感神経伸長を制御するPrincipal Investigator
- Principal Investigator
  
  濱田理人
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42030:Animal life science-related
- Research Institution
  University of Tsukuba
Development of liver fibrosis by monocyte-derived macrophages
- Principal Investigator
  
  ASANO Kenichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
Analysis of the regulatory mechanism of macrophages involved in homeostasis by the transcription factor MafBPrincipal Investigator
- Principal Investigator
  
  Hamada Michito
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  University of Tsukuba
Development of real time in vivo imaging method that can monitor tissue inflammation and fibrosis.
- Principal Investigator
  
  Takahashi Satoru
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  University of Tsukuba
Immune regulation by dead intestinal epithelial cells
- Principal Investigator
  
  ASANO Kenichi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokyo University of Pharmacy and Life Science
Regulation of Tumor associated macrophage number by transcription factor MafBPrincipal Investigator
- Principal Investigator
  
  Hamada Michito
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  University of Tsukuba
MafB regulate C1q genes in macrophagePrincipal Investigator
- Principal Investigator
  
  Hamada Michito
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  University of Tsukuba

All 2024 2021 2020 2019 2018 2017 2016 2015 2014

All Journal Article Presentation

[Journal Article] MAFB in macrophages regulates cold-induced neuronal density in brown adipose tissue2024
- Author(s)
  Yadav Manoj Kumar、Ishida Megumi、Gogoleva Natalia、Liao Ching-Wei、Salim Filiani Natalia、Kanai Maho、Kuno Akihiro、Hayashi Takuto、Shahri Zeynab Javanfekr、Kulathunga Kaushalya、Samir Omar、Lyu Wenxin、Olivia Olivia、Mbanefo Evaristus C.、Takahashi Satoru、Hamada Michito
- Journal Title
  
  Cell Reports
  
  Volume: 43 Issue: 4 Pages: 113978-113978
- DOI
  10.1016/j.celrep.2024.113978
- Data Source
  KAKENHI-PROJECT-23K05586
[Journal Article] Albino mice with the point mutation at the tyrosinase locus show high cholesterol diet-induced NASH susceptibility2021
- Author(s)
  Kulathunga Kaushalya、Wakimoto Arata、Hiraishi Yukiko、Yadav Manoj Kumar、Gentleman Kyle、Warabi Eiji、Sakasai Tomoki、Miwa Yoshihiro、Mizuno Seiya、Takahashi Satoru、Hamada Michito
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 21827-21827
- DOI
  10.1038/s41598-021-00501-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H00966, KAKENHI-PROJECT-21K05994
[Journal Article] Generation of reconstituted hemato-lymphoid murine embryos by placental transplantation into embryos lacking HSCs2021
- Author(s)
  Jeon Hyojung、Asano Keigo、Wakimoto Arata、Kulathunga Kaushalya、Tran Mai Thi Nhu、Nakamura Megumi、Yokomizo Tomomasa、Hamada Michito、Takahashi Satoru
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 4374-4374
- DOI
  10.1038/s41598-021-83652-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07499, KAKENHI-PROJECT-20K08758, KAKENHI-PROJECT-20K21513, KAKENHI-PROJECT-21K15003
[Journal Article] Role of MafB in macrophages2020
- Author(s)
  Hamada Michito、Tsunakawa Yuki、Jeon Hyojung、Yadav Manoj Kumar、Takahashi Satoru
- Journal Title
  
  Exp. Anim.
  
  Volume: 69 Issue: 1 Pages: 1-10
- DOI
  10.1538/expanim.19-0076
- NAID
  130007791547
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07499
[Journal Article] Mice Lacking Core 1-derived O-glycan in Podocytes Develop Transient Proteinuria, Resulting in Focal Segmental Glomerulosclerosis2020
- Author(s)
  Sayaka Fuseya, Riku Suzuki, Risa Okada, Kozue Hagiwara, Takashi Sato, Hisashi Narimatsu , Hideki Yokoi, Masato Kasahara, Toshiaki Usui , Naoki Morito, Kunihiro Yamagata, Takashi Kudo , Satoru Takahashi
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 523 Issue: 2 Pages: 1007-1013
- DOI
  10.1016/j.bbrc.2019.12.033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08230, KAKENHI-PROJECT-19K07499, KAKENHI-PROJECT-19K21330
[Journal Article] Transcription factor MafB is a marker of tumor-associated macrophages in both mouse and humans2020
- Author(s)
  Yadav Manoj Kumar、Inoue Yuri、Nakane-Otani Aya、Tsunakawa Yuki、Jeon Hyojung、Samir Omar、Teramoto Akari、Kulathunga Kaushalya、Kusakabe Manabu、Nakamura Megumi、Kudo Takashi、Takahashi Satoru、Hamada Michito
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 521 Issue: 3 Pages: 590-595
- DOI
  10.1016/j.bbrc.2019.10.125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07499
[Journal Article] Mice harboring an MCTO mutation exhibit renal failure resembling nephropathy in human patients2019
- Author(s)
  Yuki TSUNAKAWA, Michito HAMADA, Yurina MATSUNAGA, Sayaka FUSEYA, Hyojung JEON, Yuji WAKIMOTO, Toshiaki USUI, Maho KANAI, Seiya MIZUNO, Naoki MORITO, Satoru TAKAHASHI
- Journal Title
  
  Exp. Anim.
  
  Volume: 68 Issue: 1 Pages: 103-111
- DOI
  10.1538/expanim.18-0093
- NAID
  130007604455
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K18398
[Journal Article] Macrophages Switch Their Phenotype by Regulating Maf Expression during Different Phases of Inflammation2018
- Author(s)
  Kikuchi Kenta、Iida Mayumi、Ikeda Naoki、Moriyama Shigetaka、Hamada Michito、Takahashi Satoru、Kitamura Hiroshi、Watanabe Takashi、Hasegawa Yoshinori、Hase Koji、Fukuhara Takeshi、Sato Hideyo、Kobayashi Eri H.、Suzuki Takafumi、Yamamoto Masayuki、Tanaka Masato、Asano Kenichi
- Journal Title
  
  The Journal of Immunology
  
  Volume: 201 Issue: 2 Pages: 635-651
- DOI
  10.4049/jimmunol.1800040
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07158, KAKENHI-PROJECT-17K08977, KAKENHI-PROJECT-18K06035, KAKENHI-PROJECT-17KK0183, KAKENHI-PUBLICLY-18H04963, KAKENHI-PLANNED-26110006, KAKENHI-PROJECT-17H04052, KAKENHI-PROJECT-17H04068, KAKENHI-PROJECT-15K06805, KAKENHI-PROJECT-17K15590
[Journal Article] MafB is a critical regulator of complement component C1q2017
- Author(s)
  Tran, M.T.N., Hamada, M., Jeon, H.J., Shiraishi, R., Asano, K., Hattori, M., Nakamura, M., Imamura, Y., Tsunakawa, Y., Fujii, R., Kulathunga, K., Andrea, C.S., Koshida, R., Kamei, R., Matsunaga, Y., Kobayashi, M., Oishi, H., Kudo, T. and Takahashi, S.
- Journal Title
  
  Nature Commun.
  
  Volume: 8 Issue: 1 Pages: 1700-1700
- DOI
  10.1038/s41467-017-01711-0
- NAID
  120007128749
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26520101, KAKENHI-PROJECT-16K18398, KAKENHI-PROJECT-16H06276
[Journal Article] Differential expression patterns of MafB and c-Maf in macrophages in vivo and in vitro2016
- Author(s)
  Dhouha Daassi, Michito Hamada , Hyojung Jeon, Yuki Imamura, Mai Thi Nhu Tran, Satoru Takahashi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 473 Issue: 1 Pages: 118-124
- DOI
  10.1016/j.bbrc.2016.03.063
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25860205
[Journal Article] MafB deficiency accelerates the development of obesity in mice2016
- Author(s)
  Mai Thi Nhu Tran, Michito Hamada, Megumi Nakamura, Hyojung Jeon, Risa Kamei, Yuki Tsunakawa, Kaushalya Kulathunga, Yuan-Yu Lin, Kumiko Fujisawa, Takashi Kudo, Satoru Takahashi
- Journal Title
  
  FEBS openbio
  
  Volume: 印刷中 Issue: 6 Pages: 540-547
- DOI
  10.1002/2211-5463.12058
- NAID
  120007135330
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25860205
[Journal Article] Overexpression of Mafb in Podocytes Protects against Diabetic Nephropathy.2014
- Author(s)
  Morito N, Yoh K, Ojima M, Okamura M, Nakamura M, Hamada M, Shimohata H, Moriguchi T, Yamagata K, Takahashi S.
- Journal Title
  
  J Am Soc Nephrol.
  
  Volume: 印刷中 Issue: 11 Pages: 2546-2557
- DOI
  10.1681/asn.2013090993
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-24591223, KAKENHI-PROJECT-25860205
[Journal Article] MafB promotes atherosclerosis by inhibiting foam-cell apoptosis2014
- Author(s)
  Michito Hamada, Megumi Nakamura, Mai Thi Nhu Tran, Takashi Moriguchi, Cynthia Hong, Takayuki Ohsumi, Tra Thi Huong Dinh, Manabu Kusakabe, Motochika Hattori, Tokio Katsumata, Satoko Arai, Katsuhiko Nakashima, Takashi Kudo, Etsushi Kuroda, Chien-Hui Wu, Pei-Han Kao, Masaharu Sakai, Hitoshi Shimano, Toru Miyazaki et al
- Journal Title
  
  Nature communications
  
  Volume: 5:3147 Pages: 1-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860205
[Journal Article] <i>In Vivo</i> image Analysis Using iRFP Transgenic Mice2014
- Author(s)
  Mai Thi Nhu Tran, Junko Tanaka, Michito Hamada, Yuka Sugiyama, Shota Sakaguchi, Megumi Nakamura, Satoru Takahashi, Yoshihiro Miwa
- Journal Title
  
  Exp. Anim.
  
  Volume: 63 Issue: 3 Pages: 311-319
- DOI
  10.1538/expanim.63.311
- NAID
  130004677824
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860205
[Journal Article] Sexually dimorphic expression of Mafb regulates masculinization of the embryonic urethral formation2014
- Author(s)
  Suzuki K, Numata T, Suzuki H, Raga DD, Ipulana L, Yokoyama C, Matsushita S, Hamada M, Nakagata N, Nishinakamura R, Kume S, Takahashi S, and Yamada G.
- Journal Title
  
  PNAS
  
  Volume: 18;111(46) Issue: 46 Pages: 16407-12
- DOI
  10.1073/pnas.1413273111
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22132006, KAKENHI-PROJECT-25860205, KAKENHI-PROJECT-26670384
[Journal Article] Functions of the Large Maf Transcription Factors and Macrophages2014
- Author(s)
  Michito Hamada, Satoru Takahashi
- Journal Title
  
  Macrophages: Biology and Role in the Pathology of Diseases
  
  Volume: 1 Pages: 509-517
- DOI
  10.1007/978-1-4939-1311-4_25
- ISBN
  9781493913107, 9781493913114
- Data Source
  KAKENHI-PROJECT-25860205
[Presentation] マクロファージ特異的、Mafb欠損マウスにおける皮膚創傷治癒の遅延2024
- Author(s)
  濱田理人
- Organizer
  第１２９回日本解剖学会
- Data Source
  KAKENHI-PROJECT-23K05586
[Presentation] 創傷治癒における転写因子MafBの機能解析2019
- Author(s)
  井上由理; 濱田, 理人; 綱川祐貴; 高橋智
- Organizer
  第42回日本分子生物学会年
- Data Source
  KAKENHI-PROJECT-19K07499
[Presentation] Identifying the function of MafB expressed in macrophages during wound healing2019
- Author(s)
  井上由理; 濱田, 理人; 綱川祐貴; 高橋智
- Organizer
  Tsukuba conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07499
[Presentation] Homeostatic function of MafB in macrophages2018
- Author(s)
  濱田理人
- Organizer
  47th annual scientific meeting International society for experimental hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18398
[Presentation] 創傷治癒における転写因子MafBの機能解析2018
- Author(s)
  井上由理、綱川祐貴、濱田理人、高橋智
- Organizer
  第41回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-16K18398
[Presentation] 創傷治癒における転写因子MafBの機能解析2018
- Author(s)
  井上由理、綱川祐貴、濱田理人、高橋智
- Organizer
  第７回筑波大-理科大合同リトリート
- Data Source
  KAKENHI-PROJECT-16K18398
[Presentation] 転写因子MafBのマクロファージにおける機能解析2018
- Author(s)
  濱田理人
- Organizer
  第65回日本実験動物学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K18398
[Presentation] The transcription factor MafB is critical regulator of complement component C1q2018
- Author(s)
  濱田理人
- Organizer
  The 17th International Joint Mini-Symposium on Molecular and Cell Biology among KU-NTU-UT
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18398
[Presentation] Transcription factor MafB is indispensable for homeostatic function of macrophages2016
- Author(s)
  濱田理人
- Organizer
  第24回マクロファージ分子細胞生物学国際シンポジウム（MMCB2016）
- Place of Presentation
  sola city Conference Center, （東京都千代田区）
- Year and Date
  2016-06-04
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18398
[Presentation] Transcription factor MafB is indispensable for homeostatic function of macrophages2016
- Author(s)
  Michito Hamada
- Organizer
  第24回マクロファージ分子細胞生物学国際シンポジウム
- Place of Presentation
  東京　ソラシティカンファレンスセンター
- Year and Date
  2016-06-04
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860205
[Presentation] MafBはマクロファージにおける恒常性維持機能に重要である2015
- Author(s)
  濱田理人1、Mai Thi Nhu Tran1、浅野圭吾1、中村恵弥1、全静孝1、工藤崇、高橋智
- Organizer
  BMB2015（第38回日本分子生物学会年会、第88回日本生化学会大会合同大会）
- Place of Presentation
  兵庫　神戸ポートアイランド
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-25860205

1. ASANO Kenichi (10513400)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. Takahashi Satoru (50271896)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 水野聖哉 (10633141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 三輪佳宏 (70263845)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. MORIGUCHI Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. MORITO Naoki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. SUZUKI Kentaro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 小林麻己人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 山田源

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 佐藤英世

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hamada Michito 濱田 理人

濱田 理人 ハマダ ミチト

Research Projects

Research Products

Co-Researchers

転写因子MAFBは脂肪組織マクロファージにおいて交感神経伸長を制御するPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of liver fibrosis by monocyte-derived macrophages

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the regulatory mechanism of macrophages involved in homeostasis by the transcription factor MafBPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of real time in vivo imaging method that can monitor tissue inflammation and fibrosis.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Immune regulation by dead intestinal epithelial cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of Tumor associated macrophage number by transcription factor MafBPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

MafB regulate C1q genes in macrophagePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] MAFB in macrophages regulates cold-induced neuronal density in brown adipose tissue2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Albino mice with the point mutation at the tyrosinase locus show high cholesterol diet-induced NASH susceptibility2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Generation of reconstituted hemato-lymphoid murine embryos by placental transplantation into embryos lacking HSCs2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of MafB in macrophages2020

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Mice Lacking Core 1-derived O-glycan in Podocytes Develop Transient Proteinuria, Resulting in Focal Segmental Glomerulosclerosis2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Transcription factor MafB is a marker of tumor-associated macrophages in both mouse and humans2020

Author(s)

Journal Title

DOI

Data Source

Hamada Michito 濱田理人

濱田理人ハマダミチト