MASUDA Daisaku 増田大作

Researcher Number	20568753
Other IDs
Affiliation (based on the past Project Information) *help	2016 – 2017: 大阪大学, 医学系研究科, 特任助教 2015: 大阪大学, 医学(系)研究科(研究院), 特任助教 2014: 大阪大学, 大学院医学系研究科, 特任助教 2012 – 2014: 大阪大学, 医学(系)研究科(研究院), 研究員 2012: 大阪大学, 医学系研究科, 特任研究員 2011: 大阪大学, 医学(系)研究科(研究院), 特任研究員
Review Section/Research Field	Principal Investigator Applied health science / Circulatory organs internal medicine Except Principal Investigator Metabolomics
Keywords	Principal Investigator 耐糖能異常 / DPP4阻害薬 / リポ蛋白 / 糖尿病 / 動脈硬化 / 脳塞栓 / apoB-48 / レムナント / GLUT / FDG-PET … More / CD36 / 糖代謝 / 脂肪酸代謝 / 心筋 … More Except Principal Investigator 急性冠症候群 / 認知症 / 動脈硬化 / HDL / 炎症 / マクロファージ / プログラニュリン Less

Clinical significance of accumulation of chylomicron remnants and its functional analysis by selective isolationPrincipal Investigator
- Principal Investigator
  
  Masuda Daisaku
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Osaka University
Progranulin, a Novel HDL-Binding Protein, Suppresses Systemic Inflammation, Glucose Abnormality and Atherosclerosis
- Principal Investigator
  
  YAMASHITA Shizuya
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Osaka University
Investigation of the pathogenic mechanism of the cardiomyopathy using the knockout mouse of fatty acid transporter CD36Principal Investigator
- Principal Investigator
  
  MASUDA Daisaku
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University

All 2018 2017 2016 2015 2014 2013 2012 2011

All Journal Article Presentation Book

[Book] 血清アポリポ蛋白B-48濃度測定による動脈硬化性疾患残余リスク評価の意義2017
- Author(s)
  増田大作
- Total Pages
  9
- Publisher
  臨牀病理
- Data Source
  KAKENHI-PROJECT-15K01713
[Book] 糖尿病患者に特徴的な脂質異常とその管理2017
- Author(s)
  増田大作
- Total Pages
  4
- Publisher
  糖尿病
- Data Source
  KAKENHI-PROJECT-15K01713
[Book] 動脈硬化を起こしやすい原発性高脂血症2017
- Author(s)
  増田大作
- Total Pages
  12
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-15K01713
[Book] 食後高脂血症の意義と日常診療への応用2017
- Author(s)
  増田大作
- Total Pages
  9
- Publisher
  日本内科学会雑誌
- Data Source
  KAKENHI-PROJECT-15K01713
[Journal Article] Effects of a Dipeptidyl Peptidase 4 Inhibitor Sitagliptin on Glycemic Control and Lipoprotein Metabolism in Patients with Type 2 Diabetes Mellitus (GLORIA Trial)2018
- Author(s)
  Masuda Daisaku、Kobayashi Takuya、Sairyou Masami、Hanada Hiroyuki、Ohama Tohru、Koseki Masahiro、Nishida Makoto、Maeda Norikazu、Kihara Shinji、Minami Tatsuya、Yanagi Koji、Sakata Yasushi、Yamashita Shizuya
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 25 Issue: 6 Pages: 512-520
- DOI
  10.5551/jat.41343
- NAID
  130007382552
- ISSN
  1340-3478, 1880-3873
- Year and Date
  2018-06-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K01713, KAKENHI-PROJECT-17H02100, KAKENHI-PROJECT-18H02731
[Journal Article] A Novel Selective PPARα Modulator (SPPARMα), K-877 (Pemafibrate), Attenuates Postprandial Hypertriglyceridemia in Mice2018
- Author(s)
  Masami Sairyo, Takuya Kobayashi, Daisaku Masuda, Koutaro Kanno, Yinghong Zhu, Takeshi Okada, Masahiro Koseki, Tohru Ohama, Makoto Nishida, Yasushi Sakata, Shizuya Yamashita
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 25 Issue: 2 Pages: 142-152
- DOI
  10.5551/jat.39693
- NAID
  130006328538
- ISSN
  1340-3478, 1880-3873
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H02100, KAKENHI-PROJECT-15K01713, KAKENHI-PROJECT-18H03532
[Journal Article] Enhanced Intestinal Absorption of Cholesterol along with Increased Chylomicron Remnants for De novo Progression of Coronary Stenosis2017
- Author(s)
  Shinichi Oikawa, Shizuya Yamashita, Noriaki Nakaya, Jun Sasaki, Suminori Kono, for the Effect of Fenofibrate and Ezetimibe Combination Treatment on Lipid (EFECTL) Study Investigators
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 24 Issue: 2 Pages: 120-122
- DOI
  10.5551/jat.ED065
- NAID
  130005306537
- ISSN
  1340-3478, 1880-3873
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H02100, KAKENHI-PROJECT-15K01713
[Journal Article] Postprandial Hyperlipidemia and Remnant Lipoproteins2017
- Author(s)
  Daisaku Masuda, Shizuya Yamashita
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 24 Issue: 2 Pages: 95-109
- DOI
  10.5551/jat.RV16003
- NAID
  130005306535
- ISSN
  1340-3478, 1880-3873
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K01713, KAKENHI-PROJECT-17H02100
[Journal Article] Detrimental effects of high-fat diet loading on vascular endothelial function and therapeutic efficacy of ezetimibe and statins in patients with type 2 diabetes2016
- Author(s)
  Akira Kurozumi, Yosuke Okada, Hiroko Mori, Takuya Kobayashi, Daisaku Masuda, Shizuya Yamashita, Yoshiya Tanaka
- Journal Title
  
  Endocr J
  
  Volume: 63 Issue: 5 Pages: 431-440
- DOI
  10.1507/endocrj.EJ15-0623
- NAID
  130005154198
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K01713
[Journal Article] Deletion of progranulin exacerbates atherosclerosis in ApoE knockout mice.2013
- Author(s)
  Kawase R, Ohama T, Matsuyama A, Matsuwaki T, Okada T, Yamashita T, Yuasa-Kawase M, Nakaoka H, Nakatani K, Inagaki M, Tsubakio-Yamamoto K, Masuda D, Nakagawa-Toyama Y, Nishida M, Ohmoto Y, Nishihara M, Komuro I, Yamashita S.
- Journal Title
  
  Cardiovascular Research
  
  Volume: 100 Issue: 1 Pages: 125-133
- DOI
  10.1093/cvr/cvt178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390233
[Presentation] 家族性3型高脂血症2017
- Author(s)
  増田大作
- Organizer
  第49回日本動脈硬化学会総会・学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01713
[Presentation] 動脈硬化と関連する高中性脂肪血症の評価と治療2017
- Author(s)
  増田大作
- Organizer
  第49回日本動脈硬化学会総会・学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01713
[Presentation] Analysis of Selectively Isolated Chylomicron Remnants in Various conditions2017
- Author(s)
  Masuda D, Kobayashi T, Sairyo M, Okada T, Koseki M, Ohama T, Nishida M, Sakata Y, Yamashita S
- Organizer
  85th European Atherosclerosis Society CONGRESS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01713
[Presentation] 動脈硬化惹起的なカイロミクロンレムナント蓄積を評価する血清アポリポ蛋白B-48濃度の測定2017
- Author(s)
  増田大作
- Organizer
  第49回日本動脈硬化学会総会・学術集会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01713
[Presentation] 血清アポリポ蛋白B-48濃度測定による動脈硬化性疾患残余リスク評価の意義2017
- Author(s)
  増田大作
- Organizer
  第64回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-15K01713
[Presentation] Guidelines for Preventing Cardiovascular Diseases in Japan2017
- Author(s)
  Masuda Daisaku
- Organizer
  ICoLA2017, Seoul Korea
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01713
[Presentation] Evaluation, Analysis and Treatment of the Residual Risk of Atherosclerotic Cardiovascular Diseases, the Accumulation of Chylomicron Remnants2017
- Author(s)
  Daisaku Masuda, Takuya Kobayashi, Kohtaro Kanno, Masami Sairyou, Takeshi Okada, Tohru Ohama, Masahiro Koseki, Makoto Nishida, Yasushi Sakata and Shizuya Yamashita
- Organizer
  第81回日本循環器学会学術集会
- Place of Presentation
  金沢市
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-15K01713
[Presentation] Evaluation, Analysis and Treatment of the Residual Risk of Atherosclerotic Cardiovascular Diseases, the Accumulation of Chylomicron Remnants2017
- Author(s)
  増田大作
- Organizer
  第81回日本循環器学会、金沢
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01713
[Presentation] Increased Serum Apolipoprotein B48 Concentrations after Oral Glucose Ingestion in Patients with Diabetes Mellitus2016
- Author(s)
  MASUDA D, OKUBO M, HANADA H, MATSUI M, HIDAKA Y, SAKATA Y and YAMASHITA S
- Organizer
  76th Scientific Sessions of American Diabetes Association
- Place of Presentation
  New Orelans, USA
- Year and Date
  2016-06-10
- Data Source
  KAKENHI-PROJECT-15K01713
[Presentation] Selective Isolation and Proteomic Analysis of Intestine-derived Chylomicrons and Their Remnants in Human Serum2016
- Author(s)
  Masuda D, Matsuda H, Sairyou M, Okada T, Kawase R, Nakatani K, Koseki M, Ohama T, Nishida M, Sakata Y and Yamashita S
- Organizer
  第80回日本循環器学会総会
- Place of Presentation
  仙台、日本
- Year and Date
  2016-03-18
- Data Source
  KAKENHI-PROJECT-15K01713
[Presentation] 食後脂質異常におけるカイロミクロンレムナント蓄積の意義2016
- Author(s)
  増田大作
- Organizer
  第48回日本動脈硬化学会総会・学術集会
- Place of Presentation
  京王プラザホテル
- Year and Date
  2016-07-14
- Data Source
  KAKENHI-PROJECT-15K01713
[Presentation] 糖尿病患者に合併する動脈硬化惹起的なレムナント代謝異常2016
- Author(s)
  増田大作
- Organizer
  第31回日本糖尿病合併症学会・第22回糖尿病眼科学会総会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-15K01713
[Presentation] Increased Serum Apolipoprotein B48 Concentration In Patients With Impaired Glucose Tolerance2016
- Author(s)
  MASUDA D, OKUBO M, HANADA H, MATSUI M, HIDAKA Y, SAKATA Y and YAMASHITA S
- Organizer
  76th Scientific Sessions of American Diabetes Association
- Place of Presentation
  New Orelans, USA
- Year and Date
  2016-06-10
- Data Source
  KAKENHI-PROJECT-15K01713
[Presentation] Serum apolipoprotein B48 concentration is high in patients with impaired glucose tolerance and increases after oral glucose ingestion in patients with diabetes mellitus2016
- Author(s)
  Daisaku Masuda, Takuya Kobayashi, Masami Sairyou, Takeshi Okada, Masahiro Koseki, Tohru Ohama, Makoto Nishida, Yasushi Sakata, Shizuya Yamashita
- Organizer
  84th European Atherosclerosis Society (EAS) Congress
- Place of Presentation
  Innsbruck, Austria
- Year and Date
  2016-05-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01713
[Presentation] Proteomic analysis of atherogenic chylomicron remnants isolated selectively from human serum2016
- Author(s)
  Daisaku Masuda, Takuya Kobayashi, Masami Sairyou, Takeshi Okada, Masahiro Koseki, Tohru Ohama, Makoto Nishida, Yasushi Sakata, Shizuya Yamashita
- Organizer
  The American Heart Association (AHA) Scientific Sessions 2016 （AHA2016）
- Place of Presentation
  The American Heart Association (AHA) Scientific Sessions 2016 （AHA2016）, America
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01713
[Presentation] Proteomic analysis and comparison of selectively-isolated apolipoprotein B48- and B100-containing lipoproteins in human serum2016
- Author(s)
  Takuya Kobayashi, Daisaku Masuda, Masami Sairyo, Takeshi Okada, Ryota Kawase, Kazuhiro Nakatani, Masahiro Koseki, Tohru Ohama, Makoto Nishida, Yasushi Sakata, Shizuya Yamashita
- Organizer
  76th American Diabetes Association
- Place of Presentation
  New Orleans,　LA, America
- Year and Date
  2016-06-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01713
[Presentation] Increased serum apolipoprotein B48 concentration in patients with impaired glucose tolerance2016
- Author(s)
  Daisaku Masuda, Manabu Okubo, Hiroyuki Hanada, Masahiko Matsui, Yoh Hidaka, Yasushi Sakata, Shizuya Yamashita
- Organizer
  76th American Diabetes Association
- Place of Presentation
  New Orleans,　LA, America
- Year and Date
  2016-06-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01713
[Presentation] 食後高脂血症条件下におけるレムナントリポ蛋白のProteimics解析2016
- Author(s)
  小林卓哉, 西良雅己, 増田大作, 小関正博, 大濱　透, 坂田泰史, 山下静也
- Organizer
  第38回日本臨床栄養学会総会・第37回日本臨床栄養協会総会
- Place of Presentation
  大阪国際会議場（大阪市）
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-15K01713
[Presentation] Quantitative and Qualitative Evaluations of the Residual Risk of Atherosclerotic Cardiovascular Diseases that Focus on the Accumulation of Chylomicron Remnants2015
- Author(s)
  Masuda D, Kobayashi T, Okubo M, Kawase R, Koseki M, Ohama T, Hanada H, Nishida M, Sakata Y and Yamashita S
- Organizer
  17th International Symposium on Atherosclerosis (ISA) 2015
- Place of Presentation
  Amsterdam, the Netherlands
- Year and Date
  2015-05-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01713
[Presentation] High Levels of Serum Concentrations of Apolipoprotein B-48 in Patients with Impaired Glucose Tolerance2015
- Author(s)
  大久保学、増田大作、花田浩之、松井正博、日高洋、坂田泰史、山下静也
- Organizer
  日本動脈硬化学会総会・学術集会
- Place of Presentation
  東京、日本
- Year and Date
  2015-07-10
- Data Source
  KAKENHI-PROJECT-15K01713
[Presentation] 抗炎症性蛋白progranulin（PGRN）の急性冠症候群発症における役割2014
- Author(s)
  川瀬　良太、大濱　透、森田　雅也、黒住　祐磨、夏川　知輝、伊藤　賀敏、増田　大作、小関　正博、西田　誠、澤野　宏隆、土井　泰治、坂田　泰史、山下　静也
- Organizer
  第46回日本動脈硬化学会総会・学術集会
- Place of Presentation
  京王プラザホテル
- Year and Date
  2014-07-11
- Data Source
  KAKENHI-PROJECT-24390233
[Presentation] Progranulin Plays a Crucial Role in the development of Atherosclerosis2014
- Author(s)
  Ryota Kawase, Tohru Ohama, Akifumi Matsuyama, Yinghong Zhu,Takeshi Okada, Hajime Nakaoka, Miyako Yuasa-Kawase, Kazuhiro Nakatani, Daisaku Masuda, Masahiro Koseki, Makoto Nishida, Yasushi Sakata and Shizuya Yamashita
- Organizer
  第７８回日本循環器学会学術集会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-24390233
[Presentation] A Role of Progranulin in Acute Coronary Syndrome2014
- Author(s)
  R Kawase, T Ohama, M Morita, Y Kurozumi, N Ito, T Okada, D Masuda, M Koseki, M Nishida, H Sawano, Y Doi, Y Sakata, S Yamashita
- Organizer
  AHA2014
- Place of Presentation
  San Francisco,America
- Year and Date
  2014-11-18
- Data Source
  KAKENHI-PROJECT-24390233
[Presentation] Progranulin plays a crucial role in the development of atherosclerosis2014
- Author(s)
  R Kawase, T Ohama, A Matsuyama, Y Zhu, T Okada, K Nakatani, D Masuda, M Koseki, M Nishida, Y Sakata, S Yamashita
- Organizer
  MSDA2014
- Place of Presentation
  京都国際会議場
- Year and Date
  2014-09-13
- Data Source
  KAKENHI-PROJECT-24390233
[Presentation] Deficiency of Progranulin Aggravates Atherosclerosis Partly Due to Enhanced Inｆｌammation and Impairment of Endothelial Function2013
- Author(s)
  Ryota Kawase, Tohru Ohama, Akifumi Matsuyama, Takeshi Okada, Hajime Nakaoka, Miyako Kawase, Kazuhiro Nakatani, Kazumi Yamamoto, Daisaku Masuda, Yumiko Toyama, Makoto Nishida, Issei Komuro and Shizuya Yamashita
- Organizer
  第４５回日本動脈硬化学会総会・学術総会
- Place of Presentation
  京王プラザホテル（新宿）
- Data Source
  KAKENHI-PROJECT-24390233
[Presentation] Deletion of Progranulin Exacerbates Atherosclerosis by ChangiHDL-associated Proteins and Altering Cholesterol Homeostasis2013
- Author(s)
  Tohru Ohama, Ryota Kawase, Akifumi Matsuyama, Takeshi Okada, Hajime Nakaoka, Miyako Yuasa-Kawase, Kazuhiro Nakatani, Daisaku Masuda, Yumiko Nakagawa-Toyama, Makoto Nishida, Issei Komuro and Shizuya Yamashita
- Organizer
  第４５回日本動脈硬化学会総会・学術総会
- Place of Presentation
  京王プラザホテル（新宿）
- Data Source
  KAKENHI-PROJECT-24390233
[Presentation] hypertrophy and impaired cardiac function of CD36 knockout mice in a pressure overload condition2012
- Author(s)
  中谷和弘、増田大作、他
- Organizer
  ESC congress 2012(ヨーロッパ心臓病学会)
- Place of Presentation
  Internationales Congress Center Munchen (ドイツ、ミュンヘン)
- Year and Date
  2012-08-29
- Data Source
  KAKENHI-PROJECT-23790851
[Presentation] 圧負荷時の CD36欠損マウスにおける心肥大および心機能不全の解析2012
- Author(s)
  中谷和弘、増田大作、他
- Organizer
  日本心臓病学会年次学術集会
- Place of Presentation
  ホテル日航金沢(石川県)
- Year and Date
  2012-09-14
- Data Source
  KAKENHI-PROJECT-23790851
[Presentation] 圧負荷時のCD36欠損マウスにおける心肥大および心機能不全の解析2012
- Author(s)
  中谷和弘、増田大作、他
- Organizer
  日本心臓病学会
- Place of Presentation
  石川県金沢市
- Data Source
  KAKENHI-PROJECT-23790851
[Presentation] hypertrophy and impaired cardiac function of CD36 knockout mice in a pressure overload condition2012
- Author(s)
  中谷和弘、増田大作、他
- Organizer
  European Society of Cardiology Congress 2012
- Place of Presentation
  Munich, Germany
- Data Source
  KAKENHI-PROJECT-23790851
[Presentation] hypertrophy and impaired cardiac function of CD36 knockout mice in a pressure overload condition2012
- Author(s)
  中谷和弘、増田大作、他
- Organizer
  日本動脈硬化学会
- Place of Presentation
  福岡県博多市
- Data Source
  KAKENHI-PROJECT-23790851
[Presentation] hypertrophy and impaired cardiac function of CD36 knockout mice in a pressure overload condition2012
- Author(s)
  中谷和弘、増田大作、他
- Organizer
  日本動脈硬化学会総会
- Place of Presentation
  ヒルトン福岡シーホーク(福岡県)
- Year and Date
  2012-07-19
- Data Source
  KAKENHI-PROJECT-23790851
[Presentation] Visualization and Quantification of FDG Uptake in Myocardium of CD36-knockout Mice In Vivo Using a High Spatial Resolution Semiconductor PET2011
- Author(s)
  中谷和弘、増田大作、他
- Organizer
  第75回日本循環器学会総会・学術集会
- Place of Presentation
  みなとみらい（横浜）
- Data Source
  KAKENHI-PROJECT-23790851

1. YAMASHITA Shizuya (60243242)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results

MASUDA Daisaku 増田 大作

Research Projects

Research Products

Co-Researchers

Clinical significance of accumulation of chylomicron remnants and its functional analysis by selective isolationPrincipal Investigator

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Progranulin, a Novel HDL-Binding Protein, Suppresses Systemic Inflammation, Glucose Abnormality and Atherosclerosis

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Investigation of the pathogenic mechanism of the cardiomyopathy using the knockout mouse of fatty acid transporter CD36Principal Investigator

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[Book] 血清アポリポ蛋白B-48濃度測定による動脈硬化性疾患残余リスク評価の意義2017

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[Book] 糖尿病患者に特徴的な脂質異常とその管理2017

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[Book] 動脈硬化を起こしやすい原発性高脂血症2017

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[Book] 食後高脂血症の意義と日常診療への応用2017

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[Journal Article] Effects of a Dipeptidyl Peptidase 4 Inhibitor Sitagliptin on Glycemic Control and Lipoprotein Metabolism in Patients with Type 2 Diabetes Mellitus (GLORIA Trial)2018

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[Journal Article] A Novel Selective PPARα Modulator (SPPARMα), K-877 (Pemafibrate), Attenuates Postprandial Hypertriglyceridemia in Mice2018

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[Journal Article] Enhanced Intestinal Absorption of Cholesterol along with Increased Chylomicron Remnants for De novo Progression of Coronary Stenosis2017

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[Journal Article] Postprandial Hyperlipidemia and Remnant Lipoproteins2017

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[Journal Article] Detrimental effects of high-fat diet loading on vascular endothelial function and therapeutic efficacy of ezetimibe and statins in patients with type 2 diabetes2016

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MASUDA Daisaku 増田大作

[Presentation] 動脈硬化と関連する高中性脂肪血症の評価と治療2017