Hayase Tomo 早瀬知

… Alternative Names

HAYASE Tomo 早瀬知

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Researcher Number	20579007
Affiliation (Current)	2025: 札幌医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2013 – 2018: 札幌医科大学, 医学部, 助教 2012 – 2013: 札幌医科大学, 医学部, 研究員
Review Section/Research Field	Principal Investigator Anesthesiology / Anesthesiology/Resuscitation studies Except Principal Investigator Anesthesiology/Resuscitation studies / Anesthesiology
Keywords	Principal Investigator 麻酔科学 / 国際情報交換 / 術後悪心嘔吐 / TACR1遺伝子 / エピジェネティクス / 性差 Except Principal Investigator 麻酔科学 / 国際情報交換 / 遺伝子 / 痴呆 … More / 術後認知機能 / 術後せん妄 / 脳内発現遺伝子 / 加齢 / 手術ストレス / エイジング / 認知機能低下 / せん妄 / トランスクリプトーム解析 / 術後認知機能障害 / トランクスリプトーム / 入眠 / 遺伝子多型 / GABA受容体 / 静脈麻酔薬 / エピジェネティックス / 麻酔 / 悪心嘔吐 / エピジェネティクス Less

Analysis of a relationship between postoperative delirium or/and cognitive dysfunction and aging by transcriptome analysis
- Principal Investigator
  
  Yamakage Michiaki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Sapporo Medical University
トランスクリプトーム解析による術後悪心嘔吐の予測マーカーの確立Principal Investigator
- Principal Investigator
  
  早瀬知
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Anesthesiology
- Research Institution
  Sapporo Medical University
Analysis of cytoskeleton related genes in elderly patients
- Principal Investigator
  
  Yamakage Michiaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Anesthesiology
- Research Institution
  Sapporo Medical University
Determination of the molecular mechanism of volatile anesthetics using transcriptome analysis in thymo-cortico neurons of mice.
- Principal Investigator
  
  Yamakage Michiaki
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Sapporo Medical University
Investigation about the sex differences and postoperative nausea and vomiting using epigenome-wide association study.Principal Investigator
- Principal Investigator
  
  Hayase Tomo
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Sapporo Medical University
Association of epigenetic modulation in the TACR1 gene with opioid-induced nausea and vomiting
- Principal Investigator
  
  SUGINO Shigekazu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Sapporo Medical University
Association of genetic polymorphisms of the GABRB3 gene with the concentration of propofol at loss of consciousness
- Principal Investigator
  
  NAWA Yuko
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Sapporo Medical University

All 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Determination of the Effects of Sevoflurane Anesthesia in Different Maturing Stages of the Mouse Hippocampus by Transcriptome Analysis2017
- Author(s)
  Hayase Tomo、Tachibana Shunsuke、Yamakage Michiaki
- Journal Title
  
  Journal of Anesthesia & Clinical Research
  
  Volume: 08 Issue: 05 Pages: 1-3
- DOI
  10.4172/2155-6148.1000723
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10967
[Journal Article] The influence of depth of anesthesia on motor evoked potential response during awake craniotomy.2016
- Author(s)
  Ohtaki S, Akiyama Y, Kanno A, Noshiro S, Hayase T, Yamakage M, Mikuni N.
- Journal Title
  
  J Neurosurg
  
  Volume: 4 Pages: 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390366
[Journal Article] Effect of sevoflurane anesthesia on the comprehensive mRNA expression profile on the mouse hippocampus2016
- Author(s)
  Hayase T, Tachibana S, Yamakage M.
- Journal Title
  
  Med Gas Res
  
  Volume: 6 Pages: 1-7
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390366
[Journal Article] Effect of sevoflurane anesthesia on the comprehensive mRNA expression profile of the mouse hippocampus2016
- Author(s)
  Hayase T, Tachibana S, Yamakage M.
- Journal Title
  
  Med Gas Res
  
  Volume: 6 Pages: 1-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670673
[Journal Article] Effect of sevoflurane anesthesia on the comprehensive mRNA expression profile of the mouse hippocampus.2016
- Author(s)
  Hayase T, Tachibana S, Yamakage M.
- Journal Title
  
  Med Gas Res
  
  Volume: 6 Issue: 2 Pages: 70-76
- DOI
  10.4103/2045-9912.184715
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K20050, KAKENHI-PROJECT-16K10967
[Journal Article] TACR1 gene polymorphism and gender differences in postoperative nausea and vomiting2015
- Author(s)
  Hayase T, Sugino S, Moriya H, Yamakage M.
- Journal Title
  
  Anaesthesia
  
  Volume: Epub
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791606
[Journal Article] Recovery of postoperative cognitive function in elderly patients after a long duration of desflurane anesthesia: a pilot study.2015
- Author(s)
  Tachibana S, Hayase T, Osuda M, Kazuma S, Yamakage M.
- Journal Title
  
  J Anesth
  
  Volume: epub Issue: 4 Pages: 627-630
- DOI
  10.1007/s00540-015-1979-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390366, KAKENHI-PROJECT-25670673, KAKENHI-PROJECT-24791606
[Journal Article] TACR1 gene polymorphism is associated with gender differences in postoperative nausea and vomiting.2015
- Author(s)
  Hayase T, Sugino S, Moriya H, Yamakage M.
- Journal Title
  
  Anaesthesia
  
  Volume: 70 Issue: 10 Pages: 1148-1159
- DOI
  10.1111/anae.13082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670673, KAKENHI-PROJECT-24791606, KAKENHI-PROJECT-24390366
[Journal Article] Efficacy and Safety of a Lidocaine and Ropivacaine Mixture for Scalp Nerve Block and Local Infiltration Anesthesia in Patients Undergoing Awake Craniotomy.2014
- Author(s)
  Chaki T, Sugino S, Janicki PK, Ishioka Y, Hatakeyama Y, Hayase T, Kaneuchi-Yamashita M, Kohri N, Yamakage M.
- Journal Title
  
  J Neurosurg Anesthesiol
  
  Volume: epub Issue: 1 Pages: 1-5
- DOI
  10.1097/ana.0000000000000149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390366, KAKENHI-PROJECT-25670673, KAKENHI-PROJECT-24791606
[Journal Article] Improvement of Generic Sevoflurane by a New Production Process2014
- Author(s)
  Tomo Hayase, Shigekazu Sugino, Shun-suke Tachibana, Naoyuki Hirata and Michiaki Yamakage
- Journal Title
  
  Letters in Drug Design & Discovery
  
  Volume: 4 Issue: 4 Pages: 495-501
- DOI
  10.2174/1570180810666131113211447
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791606
[Journal Article] 麻酔科学へのオミクス研究の導入と臨床麻酔での可能性2013
- Author(s)
  杉野繁一, 早瀬知, 山蔭道明
- Journal Title
  
  麻酔
  
  Volume: 62 Pages: 296-303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390366
[Presentation] セボフルランによる異なる週齢のマウス脳の遺伝子発現変動の網羅的解析2016
- Author(s)
  早瀬　知、立花俊祐、山蔭道明
- Organizer
  第63回日本麻酔科学会
- Place of Presentation
  マリンメッセ福岡(福岡市博多区)
- Year and Date
  2016-05-26
- Data Source
  KAKENHI-PROJECT-15K20050
[Presentation] Prediction of the Molecular Mechanism of Postoperative Nausea and Vomiting Using Transcriptome Analysis2015
- Author(s)
  Hayase T, Tachibana S, Yamakage M.
- Organizer
  Anesthesiology annual meeting 2015
- Place of Presentation
  San Diego, USA
- Year and Date
  2015-10-24
- Data Source
  KAKENHI-PROJECT-24390366
[Presentation] Prediction of Molecular Mechanism of Postoperative Nausea and Vomiting Using Transcriptome Analysis.2015
- Author(s)
  Hayase T, Tachibana S, Yamakage M.
- Organizer
  The Annual Meeting of American Society of Anesthesiologists
- Place of Presentation
  San Diego, USA
- Year and Date
  2015-10-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25670673
[Presentation] Prediction of the molecular mechanism of postoperative nausea and vomiting using transcriptome analysis2015
- Author(s)
  Hayase T, Tachibana S, Yamakage M
- Organizer
  American society of anesthesiologists annual meeting 2015
- Place of Presentation
  San Diego, USA
- Year and Date
  2015-10-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24791606
[Presentation] Prediction of Molecular Mechanism of Postoperative Nausea and Vomiting Using Transcriptome Analysis2015
- Author(s)
  Hayase T, Tachibana S, Yamakage M.
- Organizer
  The Annual Meeting of American Society of Anesthesiologists
- Place of Presentation
  San Diego, USA
- Year and Date
  2015-10-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20050
[Presentation] Possible mechanism of neuroinflammation induced by surgical procedure in the mouse hippocampus determined by using transcriptome analysis2015
- Author(s)
  Tachibana S, Hayase T, Yamakage M
- Organizer
  American society of anesthesiologists annual meeting 2015
- Place of Presentation
  San Diego, USA
- Year and Date
  2015-10-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24791606
[Presentation] Possible Mechanism of Neuroinflammation Induced by Surgical Procedure in the Mouse Hippocampus Determined by Using Transcriptome Analysis2015
- Author(s)
  Tachibana S, Hayase T, Yamakage M.
- Organizer
  Anesthesiology annual meeting 2015
- Place of Presentation
  San Diego, USA
- Year and Date
  2015-10-24
- Data Source
  KAKENHI-PROJECT-24390366
[Presentation] Possible Mechanism of Neuroinflammation Induced by Surgical Procedure in the Mouse Hippocampus Determined by Using Transcriptome Analysis.2015
- Author(s)
  Tachibana S, Hayase T, Yamakage M.
- Organizer
  The Annual Meeting of American Society of Anesthesiologists
- Place of Presentation
  San Diego, USA
- Year and Date
  2015-10-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25670673
[Presentation] Possible Mechanism of Neuroinflammation Induced by Surgical Procedure in the Mouse Hippocampus Determining by Using Transcriptome Analysis.2015
- Author(s)
  Tachibana S, Hayase T, Yamakage M.
- Organizer
  The Annual Meeting of American Society of Anesthesiologists
- Place of Presentation
  San Diego, USA
- Year and Date
  2015-10-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20050
[Presentation] Recovery of Postoperative Cognitive Function in Elderly Patients After a Long Duration of Desflurane Anesthesia.2013
- Author(s)
  Satoshi Kazuma, M.D., Tomo Hayase, M.D., Michiko Osuda, M.D., Shigekazu Sugino, M.D.,Ph.D., Michiaki Yamakage, M.D.,Ph.D.
- Organizer
  American Society of Anesthesiologists Annual Meeting 2013
- Place of Presentation
  San Francisco, U.S.A
- Data Source
  KAKENHI-PROJECT-24390366
[Presentation] Oprm1 Gene Polymorphism Reduces DNA Methylation at the Upstream CpG Island in Male Patients.2013
- Author(s)
  Shigekazu Sugino, M.D.,Ph.D., Tomo Hayase, M.D., Misako Higuchi, M.D., Yuko Nawa, M.D.,Ph.D., Yukihiro Kumeta, M.D.,Ph.D., Michiaki Yamakage, M.D., Ph.D.
- Organizer
  American Society of Anesthesiologists Annual Meeting 2013
- Place of Presentation
  San Francisco, U.S.A
- Data Source
  KAKENHI-PROJECT-25670673
[Presentation] Oprm1 Gene Polymorphism Reduces DNA Methylation at the Upstream CpG Island in Male Patients.2013
- Author(s)
  Shigekazu Sugino, M.D.,Ph.D., Tomo Hayase, M.D., Misako Higuchi, M.D., Yuko Nawa, M.D.,Ph.D., Yukihiro Kumeta, M.D.,Ph.D., Michiaki Yamakage, M.D., Ph.D.
- Organizer
  American Society of Anesthesiologists 2013
- Place of Presentation
  San Francisco, U.S.A
- Data Source
  KAKENHI-PROJECT-23592301
[Presentation] Oprm1 Gene Polymorphism Reduces DNA Methylation at the Upstream CpG Island in Male Patients2013
- Author(s)
  Sugino S, Hayase T, Higuchi M, Nawa Y, Yamakage Y
- Organizer
  The Annual Meeting of American Society of Anesthesiologists
- Place of Presentation
  米国San Francisco市
- Data Source
  KAKENHI-PROJECT-23791719
[Presentation] Recovery of Postoperative Cognitive Function in Elderly Patients After a Long Duration of Desflurane Anesthesia.2013
- Author(s)
  Satoshi Kazuma, M.D., Tomo Hayase, M.D., Michiko Osuda, M.D., Shigekazu Sugino, M.D.,Ph.D., Michiaki Yamakage, M.D.,Ph.D.
- Organizer
  American Society of Anesthesiologists 2013
- Place of Presentation
  San Francisco, U.S.A
- Data Source
  KAKENHI-PROJECT-23592301
[Presentation] Recovery of Postoperative Cognitive Function in Elderly Patients After a Long Duration of Desflurane Anesthesia.2013
- Author(s)
  Satoshi Kazuma, M.D., Tomo Hayase, M.D., Michiko Osuda, M.D., Shigekazu Sugino, M.D.,Ph.D., Michiaki Yamakage, M.D.,Ph.D.
- Organizer
  American Society of Anesthesiologists Annual Meeting 2013
- Place of Presentation
  San Francisco, U.S.A
- Data Source
  KAKENHI-PROJECT-25670673
[Presentation] Oprm1 Gene Polymorphism Reduces DNA Methylation at the Upstream CpG Island in Male Patients.2013
- Author(s)
  Shigekazu Sugino, M.D.,Ph.D., Tomo Hayase, M.D., Misako Higuchi, M.D., Yuko Nawa, M.D.,Ph.D., Yukihiro Kumeta, M.D.,Ph.D., Michiaki Yamakage, M.D., Ph.D.
- Organizer
  American Society of Anesthesiologists Annual Meeting 2013
- Place of Presentation
  San Francisco, U.S.A
- Data Source
  KAKENHI-PROJECT-24390366
[Presentation] Haplotypes in human TACR1 gene are associated with postoperative nausea and vomiting2012
- Author(s)
  Hayase T, Sugino S, Tachibana S-S, Kumeta Y, Yamakage M
- Organizer
  The Annual Meeting of American Society of Anesthesiologists
- Place of Presentation
  米国Washington D.C
- Data Source
  KAKENHI-PROJECT-23592301
[Presentation] Involvement of HTR3C Gene Polymorphisms in Postoperative Pain in Lower Abdominal Surgery2012
- Author(s)
  Hayashi H, Sugino S, Hayase T, Nawa Y, Yamakage M
- Organizer
  The Annual Meeting of American Society of Anesthesiologists
- Place of Presentation
  米国Washington D.C.
- Data Source
  KAKENHI-PROJECT-23791719
[Presentation] Haptotypes in human TACR1 gene are associated with postoperative nausea and vomiting2012
- Author(s)
  Hayase T
- Organizer
  The annual meeting of the American Society of Anesthesiologists.
- Place of Presentation
  Washington, D.C.
- Data Source
  KAKENHI-PROJECT-24390366
[Presentation] Genetic variation and epigenetic modification of TAcR1 gene are associated with postoperative nausea and vomiting in surgical patients2012
- Author(s)
  Hayase T, Sugino S, Yamakage M
- Organizer
  The Annual Meeting of American Society of Human Genetics
- Place of Presentation
  米国San Francisco
- Data Source
  KAKENHI-PROJECT-23592301
[Presentation] Genetic variation in human TACR1 gene is associated with postoperative nausea and vomiting2011
- Author(s)
  Hayase T, Sugino S, Tachibana S-S, Satoh M, Yamakage M
- Organizer
  The Annual Meeting of American Society of Anesthesiologists
- Place of Presentation
  米国Chicago
- Data Source
  KAKENHI-PROJECT-23592301
[Presentation] Estradiol Enhances Female Pica Behavior Through TACR1 Expression in the Caudate Putamen
- Author(s)
  Tomo Hayase, M.D., Shigekazu Sugino, M.D., Ph.D., Shun-suke Tachibana, M.D., Michiaki Yamakage, M.D., Ph.D.
- Organizer
  American Society of Anesthesiologists Annual Meeting 2014
- Place of Presentation
  New Orleans, USA
- Year and Date
  2014-10-11 – 2014-10-15
- Data Source
  KAKENHI-PROJECT-24390366
[Presentation] TACR1 Gene Polymorphism Is Associated With Gender Difference in Postoperative Nausea and Vomiting
- Author(s)
  Hayase T, Sugino S, Tachibana S, Yamakage M.
- Organizer
  The annual meeting of the American Society of Anesthesiologists
- Place of Presentation
  New Orleans, USA
- Year and Date
  2014-10-11 – 2014-10-15
- Data Source
  KAKENHI-PROJECT-24791606
[Presentation] Estradiol Enhances Female Pica Behavior Through TACR1 Expression in the Caudate Putamen
- Author(s)
  Hayase T, Sugino S, Tachibana S, Yamakage M.
- Organizer
  The annual meeting of the American Society of Anesthesiologists
- Place of Presentation
  New Orleans, USA
- Year and Date
  2014-10-11 – 2014-10-15
- Data Source
  KAKENHI-PROJECT-24791606
[Presentation] TACR1 Gene Polymorphism Is Associated With Gender Difference in Postoperative Nausea and Vomiting
- Author(s)
  Tomo Hayase, M.D., Shigekazu Sugino, M.D., Ph.D., Shun-suke Tachibana, M.D., Michiaki Yamakage, M.D., Ph.D.
- Organizer
  American Society of Anesthesiologists Annual Meeting 2014
- Place of Presentation
  New Orleans, USA
- Year and Date
  2014-10-11 – 2014-10-15
- Data Source
  KAKENHI-PROJECT-24390366

1. YAMAKAGE Michiaki (70285005)

# of Collaborated Projects: 6 results

# of Collaborated Products: 31 results
2. SUGINO Shigekazu (00423765)

# of Collaborated Projects: 4 results

# of Collaborated Products: 16 results
3. NAWA Yuko (90586794)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. MORIYA Hiroyuki (00337049)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TACHIBANA Shun-suke

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. SATO Michiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TACHIBANA SHUNSUKE

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Hayase Tomo 早瀬 知

HAYASE Tomo 早瀬 知

Research Projects

Research Products

Co-Researchers

Analysis of a relationship between postoperative delirium or/and cognitive dysfunction and aging by transcriptome analysis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

トランスクリプトーム解析による術後悪心嘔吐の予測マーカーの確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of cytoskeleton related genes in elderly patients

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Determination of the molecular mechanism of volatile anesthetics using transcriptome analysis in thymo-cortico neurons of mice.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation about the sex differences and postoperative nausea and vomiting using epigenome-wide association study.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Association of epigenetic modulation in the TACR1 gene with opioid-induced nausea and vomiting

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Association of genetic polymorphisms of the GABRB3 gene with the concentration of propofol at loss of consciousness

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Determination of the Effects of Sevoflurane Anesthesia in Different Maturing Stages of the Mouse Hippocampus by Transcriptome Analysis2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The influence of depth of anesthesia on motor evoked potential response during awake craniotomy.2016

Author(s)

Journal Title

Data Source

[Journal Article] Effect of sevoflurane anesthesia on the comprehensive mRNA expression profile on the mouse hippocampus2016

Author(s)

Journal Title

Data Source

[Journal Article] Effect of sevoflurane anesthesia on the comprehensive mRNA expression profile of the mouse hippocampus2016

Author(s)

Journal Title

Data Source

[Journal Article] Effect of sevoflurane anesthesia on the comprehensive mRNA expression profile of the mouse hippocampus.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] TACR1 gene polymorphism and gender differences in postoperative nausea and vomiting2015

Author(s)

Journal Title

Data Source

[Journal Article] Recovery of postoperative cognitive function in elderly patients after a long duration of desflurane anesthesia: a pilot study.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] TACR1 gene polymorphism is associated with gender differences in postoperative nausea and vomiting.2015

Author(s)

Hayase Tomo 早瀬知

HAYASE Tomo 早瀬知