Izawa Takeshi 井澤武史

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IZAWA Takeshi 井澤武史

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Researcher Number	20580369
Other IDs
Affiliation (Current)	2025: 大阪公立大学, 大学院獣医学研究科 , 准教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 大阪公立大学, 大学院獣医学研究科, 准教授 2016 – 2021: 大阪府立大学, 生命環境科学研究科, 准教授 2015 – 2016: 大阪府立大学, 生命環境科学研究科(系), 准教授 2011 – 2014: 大阪府立大学, 生命環境科学研究科(系), 助教 2013: 大阪府立大学, 生命環境科学研究科, 助教 2010 – 2011: 大阪府立大学, 生命環境科学研究科, 助教
Review Section/Research Field	Principal Investigator Veterinary medical science / Basic veterinary science/Basic zootechnical science / Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Basic Section 42020:Veterinary medical science-related Except Principal Investigator Basic Section 42020:Veterinary medical science-related / Veterinary medical science / Clinical veterinary science / Basic Section 63030:Chemical substance influence on environment-related / Basic Section 38050:Food sciences-related
Keywords	Principal Investigator 炎症 / 薬剤性肝障害 / マクロファージ / 鉄過剰 / 慢性肝疾患 / 肝硬変 / 鉄代謝 / 肝毒性 / 脂肪肝 / 薬剤性肝傷害 … More / 代謝性肝疾患 / 鉄代謝障害 / 鉄調節因子 / 細胞接着 / ヒト化マウス / 細胞保護作用 / 細胞保護機構 / 薬物性肝障害 / 細胞死 / 脂肪性肝疾患 / 肝鉄過剰 / 毒性病理学 / 薬物代謝 / アセトアミノフェン / マウス / メタボリック症候群 / 肝疾患 / メタボリックシンドローム / 酸化ストレス / 肝障害 / 線維化 / 代謝性疾患 / miRNA / 動物モデル / hepcidin / ミエリン疾患 / 肝線維化 / 難治疾患 … More Except Principal Investigator 筋線維芽細胞 / 線維化 / 肝線維化 / マクロファージ / 酸化ストレス / 脱髄 / 多発性硬化症 / モデル動物 / ミエリン / オリゴデンドロサイト / 上皮‐間葉転換 / 臓器横断的解析 / 臓器横断的 / ラット / 体性幹細胞 / EMT / 腎線維化 / オートファジー / ミトコンドリア / 動物モデル / ミエリン変性 / 付加体 / M2FA / ADH5 / ALDH2 / ホルムアルデヒド / 上皮間葉転換 / 線維化の軽減実験 / 難治性線維化 / 幹細胞認識抗体 / ストレス応答 / インスリン分泌 / 食品成分 / Redd2/Ddit4l / 高脂肪食 / 2型糖尿病 / アポトーシス / インスリン / アンドロゲン / 咀嚼 / ストレプトゾトシン / p53 / Nrf2 / 膵β細胞 / Redd2 / 難治性疾患 / 皮膚線維化 / 病理学 / Thy-1 / 膵線維化 / 遡及現象 / 線維化腎 / α-平滑筋アクチン / betaーカテニン / 萎縮腎 / 獣医病理学 / PGE2 / 平滑筋アクチン / 幹細胞 / 毛根鞘細胞 / 毛嚢上皮 / 胆管上皮 / 尿細管上皮 / 上皮－間葉転換 / Galactin-3 / HSP25 / 創傷治癒線維化 / 抗原提示能 / カルポニン / Hsp25 / 皮膚創傷治癒 / 胆管周囲線維化 / 細胞骨格 / 抗原提示マクロファージ / 皮膚創傷治癒線維化 / 慢性腎臓病 / プロスタグランデン / 尿細管再生 / MHCクラスII / 誘導因子 Less

Elucidation of mechanism underlying toxicity resistance by human hepatocytes based on cell adhesion abnormalityPrincipal Investigator
- Principal Investigator
  
  井澤武史
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  Osaka Metropolitan University
Diseases caused by the accumulation of endogenous formaldehyde
- Principal Investigator
  
  中村純
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 63030:Chemical substance influence on environment-related
- Research Institution
  Osaka Metropolitan University
  Osaka Prefecture University
Elucidating the mechanisms of intractable myelin disease using comparative pathological models
- Principal Investigator
  
  桑村充
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Osaka Metropolitan University
  Osaka Prefecture University
Elucidation of novel mechanism for hepatoprotection by iron overloadPrincipal Investigator
- Principal Investigator
  
  Izawa Takeshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Osaka Metropolitan University
  Osaka Prefecture University
Mechanistic study on defects in pancreatic beta-cell function, and its prevention by food factors
- Principal Investigator
  
  Harada Naoki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Osaka Prefecture University
Basic study on epithelial-mesenchymal transition leading to intractable fibrosis based on the somatic stem cells
- Principal Investigator
  
  Yamate Jyoji
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Osaka Metropolitan University
  Osaka Prefecture University
Elucidation of the mechanism for disease modulation by iron overload in chronic liver diseasesPrincipal Investigator
- Principal Investigator
  
  Izawa Takeshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Veterinary medical science
- Research Institution
  Osaka Prefecture University
Molecular mechanisms of drug-induced liver injury based on metabolic liver diseasePrincipal Investigator
- Principal Investigator
  
  Izawa Takeshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Research Field
  
  Veterinary medical science
- Research Institution
  Osaka Prefecture University
Analyses of new relationship between myelin and neurons for elucidaion of myelin degenerative disease
- Principal Investigator
  
  Kuwamura Mitsuru
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Veterinary medical science
- Research Institution
  Osaka Prefecture University
Based on the axis between macrophages and myofibroblasts, the organ-cross pathogenesis of incurable fibrosis
- Principal Investigator
  
  Yamate Jyoji
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Veterinary medical science
- Research Institution
  Osaka Prefecture University
Elucidation of inflammatory mechanism and pathologic role in iron dysregulation in chronic liver diseases.Principal Investigator
- Principal Investigator
  
  Izawa Takeshi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Veterinary medical science
- Research Institution
  Osaka Prefecture University
Molecular pathology of iron dysregulation during progression of liver cirrhosisPrincipal Investigator
- Principal Investigator
  
  IZAWA Takeshi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Osaka Prefecture University
Pathogenesis of epithelial-mesenchymal transition relating to progressing fibrosis and its clinical significance
- Principal Investigator
  
  YAMATE Jyoji
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Clinical veterinary science
- Research Institution
  Osaka Prefecture University
The pathogenesis of progressive chronic renal disease and therapeutic strategies, based on the axis of macrophages and myofibroblasts
- Principal Investigator
  
  YAMATE Jyoji
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Clinical veterinary science
- Research Institution
  Osaka Prefecture University
Pathological roles of iron metabolism in rat models of myelin disease and hepatic fibrosisPrincipal Investigator
- Principal Investigator
  
  IZAWA Takeshi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Osaka Prefecture University

[Journal Article] Myelin lesion in the aspartoacylase (Aspa) knockout rat, an animal model for Canavan disease.2024
- Author(s)
  Takeda S, Hoshiai R, Tanaka M, Izawa T, Yamate J, Kuramoto T, Kuwamura M
- Journal Title
  
  Exp Anim (in press)
  
  Volume: －
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K21277
[Journal Article] Absence of increased susceptibility to acetaminophen-induced liver injury in a diet induced NAFLD mouse model2023
- Author(s)
  Izawa T, Travlos GS, Cortes RA, Clayton NP, Sills RC, Pandiri AR
- Journal Title
  
  Toxicologic Pathology
  
  Volume: in press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06415
[Journal Article] Possible cytoprotection of low dose lipopolysaccharide in rat thioacetamide-induced liver lesions, focusing on the analyses of hepatic macrophages and autophagy.2022
- Author(s)
  Pervin M, Karim MR, Kuramochi M, Izawa T, Kuwamura M, Yamate J
- Journal Title
  
  Toxicol Pathol.
  
  Volume: 50 Issue: 3 Pages: 353-365
- DOI
  10.1177/01926233221076758
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03130
[Journal Article] Dietary iron overload enhances Western diet induced hepatic inflammation and alters lipid metabolism in rats sharing similarity with human DIOS2022
- Author(s)
  Fujiwara Sakura、Izawa Takeshi、Mori Mutsuki、Atarashi Machi、Yamate Jyoji、Kuwamura Mitsuru
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 21414-21414
- DOI
  10.1038/s41598-022-25838-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06415
[Journal Article] Analyses of hemorrhagic diathesis in high-iron diet-fed rats2021
- Author(s)
  Inai Yohei、Izawa Takeshi、Mori Mutsuki、Atarashi Machi、Tsuchiya Seiichirou、Kuwamura Mitsuru、Yamate Jyoji
- Journal Title
  
  Journal of Toxicologic Pathology
  
  Volume: 34 Issue: 1 Pages: 33-41
- DOI
  10.1293/tox.2020-0004
- NAID
  130007982457
- ISSN
  0914-9198, 1881-915X
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06415
[Journal Article] Involvement of neutrophils in rat livers by low-dose thioacetamide administration2021
- Author(s)
  Kuramochi M, Izawa T, Kuwamura M, Yamate J.
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 83 Issue: 3 Pages: 390-396
- DOI
  10.1292/jvms.20-0581
- NAID
  130007996809
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03130
[Journal Article] Appearance of heterogeneous macrophages during development of isoproterenol-induced rat myocardial fibrosis.2021
- Author(s)
  Koga M, Karim MR, Kuramochi M, Izawa T, Kuwamura M, Yamate J.
- Journal Title
  
  Toxicol Pathol
  
  Volume: 49 Issue: 5 Pages: 1048-1061
- DOI
  10.1177/0192623320982526
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03130
[Journal Article] Immunophenotypical characterization of M1/M2 macrophages and lymphocytes in cisplatin-induced rat progressive renal fibrosis.2021
- Author(s)
  Nakagawa M, Karim MR, Izawa T, Kuwamura M, Yamate J.
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 2 Pages: 257-257
- DOI
  10.3390/cells10020257
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03130
[Journal Article] Properties of macrophages and lymphocytes appearing in rat renal fibrosis followed by repeated injection of cisplatin2021
- Author(s)
  Matsuyama S, Pervin M, Nakagawa M, Izawa T, Kuwamura M, Yamate J.
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 83 Issue: 9 Pages: 1435-1442
- DOI
  10.1292/jvms.21-0341
- NAID
  130008088057
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03130
[Journal Article] Acetaminophen-Induced Rat Hepatotoxicity Based on M1/M2-Macrophage Polarization, in Possible Relation to Damage-Associated Molecular Patterns and Autophagy2020
- Author(s)
  Tsuji Y, Kuramochi M, Golbar HM, Izawa T, Kuwamura M, Yamate J.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 21 Issue: 23 Pages: 8998-8998
- DOI
  10.3390/ijms21238998
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03130
[Journal Article] Participation of Somatic Stem Cells, Recognized by a Unique A3 Antibody, in Mucosal Epithelial Regeneration in Dextran Sulfate Sodium (DSS)-Induced Rat Colonic Lesions2020
- Author(s)
  Nishina H, Katou-Ichikawa C, Kuramochi M, Izawa T, Kuwamura M, Yamate J
- Journal Title
  
  Toxicol Pathol.
  
  Volume: 48 Issue: 4 Pages: 560-569
- DOI
  10.1177/0192623320906817
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03130
[Journal Article] Participation of Somatic Stem Cells, Labeled by a Unique Antibody (A3) Recognizing both N-glycan and Peptide, to Hair Follicle Cycle and Cutaneous Wound Healing in Rats.2020
- Author(s)
  Katou-Ichikawa C, Nishina H, Tanaka M, Takenaka S, Izawa T, Kuwamura M, Yamate J.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 21 Issue: 11 Pages: 3806-3806
- DOI
  10.3390/ijms21113806
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03130
[Journal Article] Characterization of Macrophages and Myofibroblasts Appearing in Dibutyltin Dichloride-Induced Rat Pancreatic Fibrosis.2020
- Author(s)
  Hashimoto A, Karim MR, Kuramochi M, Izawa T, Kuwamura M, Yamate J
- Journal Title
  
  Toxicol Pathol.
  
  Volume: 48 Issue: 3 Pages: 509-523
- DOI
  10.1177/0192623319893310
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03130
[Journal Article] Relationship between gut environment, feces-to-food ratio, and androgen deficiency-induced metabolic disorders2020
- Author(s)
  Harada Naoki、Minami Yukari、Hanada Kazuki、Hanaoka Ryo、Kobayashi Yasuyuki、Izawa Takeshi、Sato Takashi、Kato Shigeaki、Inui Hiroshi、Yamaji Ryoichi
- Journal Title
  
  Gut Microbes
  
  Volume: 12 Issue: 1 Pages: 1817719-1817719
- DOI
  10.1080/19490976.2020.1817719
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06435, KAKENHI-PROJECT-19H02913
[Journal Article] Effects of dexamethasone on hepatic macrophages in normal livers and thioacetamide-induced acute liver lesions in rats2020
- Author(s)
  Hada N, Kuramochi M, Izawa T, Kuwamura M, Yamate J.
- Journal Title
  
  Journal of Toxicologic Pathology
  
  Volume: 33 Issue: 4 Pages: 237-246
- DOI
  10.1293/tox.2020-0016
- NAID
  130007931392
- ISSN
  0914-9198, 1881-915X
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03130
[Journal Article] Dietary Iron Overload Differentially Modulates Chemically-Induced Liver Injury in Rats2020
- Author(s)
  Mori Mutsuki、Izawa Takeshi、Inai Yohei、Fujiwara Sho、Aikawa Ryo、Kuwamura Mitsuru、Yamate Jyoji
- Journal Title
  
  Nutrients
  
  Volume: 12 Issue: 9 Pages: 2784-2784
- DOI
  10.3390/nu12092784
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06415
[Journal Article] Immunohistochemical characterization of myofibroblasts appearing in isoproterenol-induced rat myocardial fibrosis2019
- Author(s)
  Koga M, Kuramochi M, Karim MR, Izawa T, Kuwamura M, Yamate J.
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 81 Issue: 1 Pages: 127-133
- DOI
  10.1292/jvms.18-0599
- NAID
  130007556803
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03130
[Journal Article] The role of iron overload in the progression of nonalcoholic steatohepatitis (NASH)2019
- Author(s)
  新真智, 井澤武史, 桑村充, 山手丈至
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 154 Issue: 2 Pages: 61-65
- DOI
  10.1254/fpj.154.61
- NAID
  130007689318
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08084
[Journal Article] Downregulation of aspartoacylase during the progression of myelin breakdown in the dmy mutant rat with mitochondrial magnesium channel MRS2 defect2019
- Author(s)
  Mitsuru Kuwamura, Satomi Tanimura, Yuko Hasegawa, Rika Hoshiai, Yushi Moriyama, Miyuu Tanaka, Shigeo Takenaka, Haruna Nagayoshi, Takeshi Izawa, Jyoji Yamate, Takashi Kuramoto, Tadao Serikawa
- Journal Title
  
  Brain Research
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04595
[Journal Article] The localization and distribution of cells labeled by a somatic stem cell-recognizing antibody (A3) in rat colon development; possible presence of a new cell type forming the intestinal stem cell niche2019
- Author(s)
  Nishina H, Katou-Ichikawa C, Kuramochi M, Izawa T, Kuwamura M, Yamate J.
- Journal Title
  
  Journal of Toxicologic Pathology
  
  Volume: 32 Issue: 1 Pages: 37-48
- DOI
  10.1293/tox.2018-0037
- NAID
  130007575091
- ISSN
  0914-9198, 1881-915X
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03130
[Journal Article] Dietary iron overload abrogates chemically-induced liver cirrhosis in rats.2018
- Author(s)
  Atarashi M, Izawa T, Mori M, Inai Y, Kuwamura M, Yamate J
- Journal Title
  
  Nutrients
  
  Volume: 10 Issue: 10 Pages: 1400-1400
- DOI
  10.3390/nu10101400
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08084
[Journal Article] Dietary Iron Supplementation Alters Hepatic Inflammation in a Rat Model of Nonalcoholic Steatohepatitis2018
- Author(s)
  Machi Atarashi、Takeshi Izawa、Rena Miyagi、Shoko Ohji、Ai Hashimoto、Mitsuru Kuwamura、Jyoji Yamate
- Journal Title
  
  Nutrients
  
  Volume: 10 Issue: 2 Pages: 175-175
- DOI
  10.3390/nu10020175
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08084
[Journal Article] Immunolocalization of β-catenin, E-cadherin and N-cadherin in neonate and adult rat kidney2017
- Author(s)
  Terada N, Karim MR, Izawa T, Kuwamura M, Yamate J.
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 79 Issue: 11 Pages: 1785-1790
- DOI
  10.1292/jvms.17-0439
- NAID
  130006199252
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26292152
[Journal Article] Immunophenotypical analysis of pancreatic interstitial cells in the developing rat pancreas and myofibroblasts in the fibrotic pancreas in dogs and cats2017
- Author(s)
  Hashimoto A, Karim MR, Izawa T, Kuwamura M, Yamate J.
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 79 Issue: 12 Pages: 1920-1926
- DOI
  10.1292/jvms.17-0423
- NAID
  130006246746
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26292152
[Journal Article] Attenuation of alpha-naphthylisothiocyanate (ANIT)-induced biliary fibrosis by depletion of hepatic macrophages in rats.2017
- Author(s)
  Golbar HM, Izawa T, Bondoc A, Wijesundera KK, Tennakoon AH, Kuwamura M, Yamate J.
- Journal Title
  
  Exp Toxicol Pathol.
  
  Volume: 69 Issue: 4 Pages: 221-230
- DOI
  10.1016/j.etp.2017.01.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26292152
[Journal Article] Attenuation of thioacetamide-induced hepatocellular injury by short-term repeated injections associated with down-regulation of metabolic enzymes and relationship with MHC class II-presenting cells.2017
- Author(s)
  Kuramochi M, Izawa T, Pervin M, Bondoc A, Kuwamura M, LaMarre J, Yamate J.
- Journal Title
  
  Exp Toxicol Pathol.
  
  Volume: 69 Issue: 8 Pages: 589-597
- DOI
  10.1016/j.etp.2017.05.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26292152
[Journal Article] Participation of tumor-associated myeloid cells in progression of amelanotic melanoma (RMM Tumor Line) in F344 Rats, with particular reference to MHC Class II- and CD163-expressing cells.2017
- Author(s)
  Bondoc A, Golbar HM, Pervin M, Katou-Ichikawa C, Tanaka M, Izawa T, Kuwamura M, Yamate J.
- Journal Title
  
  Cancer Microenviron.
  
  Volume: 10 Issue: 1-3 Pages: 9-24
- DOI
  10.1007/s12307-017-0193-x
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26292152
[Journal Article] Characterization of pancreatic islet cell tumors and renal tumors induced by a combined treatment of streptozotocin and nicotinamide in male SD rats.2017
- Author(s)
  Kato Y, Masuno K, Fujisawa K, Tsuchiya N, Torii M, Hishikawa A, Izawa T, Kuwamura M, Yamate J.
- Journal Title
  
  Exp Toxicol Pathol.
  
  Volume: 69 Issue: 7 Pages: 413-423
- DOI
  10.1016/j.etp.2017.03.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26292152
[Journal Article] Immunophenotypical characterization and influence on liver homeostasis of depleting and repopulating hepatic macrophages in rats injected with clodronate.2016
- Author(s)
  Pervin M, Golbar HM, Bondoc A, Izawa T, Kuwamura M, Yamate J.
- Journal Title
  
  Exp Toxicol Pathol.
  
  Volume: 68 Issue: 2-3 Pages: 113-124
- DOI
  10.1016/j.etp.2015.11.003
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26292152
[Journal Article] Enhanced Expression of Trib3 during the Development of Myelin Breakdown in dmy Myelin Mutant Rats.2016
- Author(s)
  Shimotsuma Y, Tanaka M, Izawa T, Yamate J, Kuwamura M
- Journal Title
  
  PLoS One
  
  Volume: 11(12) Issue: 12 Pages: e0168250-e0168250
- DOI
  10.1371/journal.pone.0168250
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04595
[Journal Article] M1-/M2-macrophage polarization in pseudolobules consisting of adipohilin-rich hepatocytes in thioacetamide (TAA)-induced rat hepatic cirrhosis.2016
- Author(s)
  Wijesundera KK, Izawa T, Tennakoon AH, Golbar HM, Tanaka M, Kuwamura M, Yamate J.
- Journal Title
  
  Exp Mole Pathol
  
  Volume: 101 Issue: 1 Pages: 133-142
- DOI
  10.1016/j.yexmp.2016.07.005
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26292152
[Journal Article] Histopathological Analysis of Rat Hepatotoxicity Based on Macrophage Functions: in Particular, an Analysis for Thioacetamide-induced Hepatic Lesions2016
- Author(s)
  Yamate J, Izawa T, Kuwamura M.
- Journal Title
  
  Food Safety
  
  Volume: 4 Issue: 3 Pages: 61-73
- DOI
  10.14252/foodsafetyfscj.2016012
- NAID
  130005267072
- ISSN
  2187-8404
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26292152
[Journal Article] Transient effects of empty liposomes on hepatic macrophage populations in rats2016
- Author(s)
  Pervin M, Golbar HM, Bondoc A, Izawa T, Kuwamura M, Yamate J.
- Journal Title
  
  Journal of Toxicologic Pathology
  
  Volume: 29 Issue: 2 Pages: 139-144
- DOI
  10.1293/tox.2015-0082
- NAID
  130005151011
- ISSN
  0914-9198, 1881-915X
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26292152
[Journal Article] The kinetics of damage-associated molecular patterns (DAMPs) and Toll-like receptors during thioacetamide-induced acute liver injury in rats.2016
- Author(s)
  Kuramochi M, Izawa T, Pervin M, Bondoc A, Kuwamura M, Yamate J.
- Journal Title
  
  Exp Toxicol Pathol .
  
  Volume: 68 Issue: 8 Pages: 471-477
- DOI
  10.1016/j.etp.2016.06.005
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26292152
[Journal Article] Depletion of hepatic macrophages aggravates liver lesions induced in rats by thioacetamide (TAA).2016
- Author(s)
  Golbar HM, Izawa T, Wijesundera KK, Bondoc A, Tennakoon AH, Kuwamura M, Yamate J.
- Journal Title
  
  Toxicol Pathol.
  
  Volume: 44 Issue: 2 Pages: 246-258
- DOI
  10.1177/0192623315621191
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26292152
[Journal Article] Pathogenesis of type 2 epithelial to mesenchymal transition (EMT) in renal and hepatic fibrosis.2015
- Author(s)
  Tennakoon AH, Izawa T, Kuwamura M, Yamate J.
- Journal Title
  
  Journal of Clinical Medicine (Review)
  
  Volume: 5 Issue: 1 Pages: 1-16
- DOI
  10.3390/jcm5010004
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26292152
[Journal Article] M1-/M2-macrophages contribute to the development of glutathione S-transferase placental form (GST-P)-positive pseudolobules in thioacetamide-induced rat cirrhosis.2015
- Author(s)
  Wijesundera KK, IzawaT, TennakoonAH, Murakami H, Golbar HM, Katou-Ichikawa C, Tanakawa M, Kuwamura M, Yamate J.
- Journal Title
  
  Experimental and Toxicologic Pathology
  
  Volume: 67 Issue: 9 Pages: 467-475
- DOI
  10.1016/j.etp.2015.05.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26292152
[Journal Article] Analysis of glial fibrillary acidic protein (GFAP)-expressing ductular cells in a rat liver cirrhosis model induced by repeated injections of thioacetamide (TAA)2015
- Author(s)
  Tennakoon, A. H. Izawa, T. Wijesundera, K. K. Katou-Ichikawa, C. Tanaka, M. Golbar, H. M. Kuwamura, M. Yamate, J.
- Journal Title
  
  Experimental and Molecular Pathology
  
  Volume: 98 Issue: 3 Pages: 476-485
- DOI
  10.1016/j.yexmp.2015.03.010
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26850184, KAKENHI-PROJECT-26292152
[Journal Article] Immunohistochemical characterization of glial fibrillary acidic protein (GFAP)-expressing cells in a rat liver cirrhosis model induced by repeated injections of thioacetamide (TAA)2015
- Author(s)
  Tennakoon, A. H. Izawa, T. Wijesundera, K. K. Murakami, H. Katou-Ichikawa, C. Tanaka, M. Golbar, H. M. Kuwamura, M. Yamate, J.
- Journal Title
  
  Experimental and Toxicologic Pathology
  
  Volume: 67 Issue: 1 Pages: 53-63
- DOI
  10.1016/j.etp.2014.09.008
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26850184
[Journal Article] Anti-fibrotic role of miR-214 in thioacetamide-induced liver cirrhosis in rats2015
- Author(s)
  Izawa, T. Horiuchi, T. Atarashi, M. Kuwamura, M. Yamate, J.
- Journal Title
  
  Toxicologic Pathology
  
  Volume: in press Issue: 6 Pages: 844-851
- DOI
  10.1177/0192623315573587
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26850184
[Journal Article] M1- and M2-macrophage polarization in rat liver cirrhosis induced by thioacetamide (TAA), focusing on Iba1 and galectin-32014
- Author(s)
  Wijesundera KK, Izawa T(共同筆頭著者), Tennakoon AH, Murakami H, Golbar HM, Katou-Ichikawa C, Tanaka M, Kuwamura M, Yamate J
- Journal Title
  
  Exp Mol Pathol
  
  Volume: 96(3) Pages: 382-392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24780288
[Journal Article] M1- and M2-macrophage polarization in rat liver cirrhosis induced by thioacetamide (TAA), focusing on Iba1 and galectin-32014
- Author(s)
  Wijesundera KK, Izawa T, Tennakoon AH, Murakami H, Golbar HM, Kato-Ichikawa C, Tanaka M, Kuwamura M, Yamate J
- Journal Title
  
  Exp Mol Pathol
  
  Volume: in press Issue: 3 Pages: 382-392
- DOI
  10.1016/j.yexmp.2014.04.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24780288, KAKENHI-PROJECT-26292152, KAKENHI-PROJECT-26850184
[Journal Article] M1- and M2-macrophage polarization in thioacetamide (TAA)-induced rat liver lesions; a possible analysis for hepato-pathology2014
- Author(s)
  Wijesundera KK, Izawa T, Murakami H, Tennakoon AH, Golbar HM, Kato-Ichikawa C, Tanaka M, Kuwamura M, Yamate J
- Journal Title
  
  Histol Histopathol
  
  Volume: 29(4) Pages: 497-511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24780288
[Journal Article] M1- and M2-macrophage polarization in thioacetamide (TAA)-induced rat liver lesions; a possible analysis for hepato-pathology2014
- Author(s)
  Wijesundera, K.K., Izawa, T., Murakami, H., Tennakoon, A.H., Golbar, H.M., Kato-Ichikawa, C., Tanaka, M., Kuwamura, M., Yamate, J
- Journal Title
  
  Histol Histopathol
  
  Volume: 29 Pages: 497-511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380173
[Journal Article] Calponin Expression in Renal Tubulointerstitial Fibrosis Induced in Rats by Cisplatin2014
- Author(s)
  Yuasa, T., Yano, R., Izawa, T., Kuwamura, M., Yamate, J
- Journal Title
  
  Journal of Toxicologic Pathology
  
  Volume: 27 Issue: 1 Pages: 97-103
- DOI
  10.1293/tox.2013-0048
- NAID
  130003391344
- ISSN
  0914-9198, 1881-915X
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23658265, KAKENHI-PROJECT-26292152
[Journal Article] Inflammatory regulation of iron metabolism during thioacetamide-induced acute liver injury in rats2014
- Author(s)
  Izawa T, Murakami H, Wijesundera KK, Golbar HM, Kuwamura M, Yamate J
- Journal Title
  
  Exp Toxicol Pathol
  
  Volume: 66 Issue: 2-3 Pages: 155-62
- DOI
  10.1016/j.etp.2013.12.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24780288
[Journal Article] Involvement of neutrophil gelatinase-associated lipocalin and osteopontin in renal tubular regeneration and interstitial fibrosis after cisplatin-induced renal failure2014
- Author(s)
  Kashiwagi E, Tonomura Y, Kondo C, Masuno K, Fujisawa K, Tsuchiya N, Matsushima S, Torii M, Takasu N, Izawa T, Kuwamura M, Yamate J
- Journal Title
  
  Experimental and Toxicologic Pathology
  
  Volume: 66 Issue: 7 Pages: 301-311
- DOI
  10.1016/j.etp.2014.04.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26292152
[Journal Article] M1- and M2-macrophage polarization in thioacetamide (TAA)-induced rat liver lesions; a possible analysis for hepato-pathology2014
- Author(s)
  Wijesundera KK, Izawa T, Murakami H, Tennakoon AH, Golbar HM, Katou-Ichikawa C, Tanaka M, Kuwamura M, Yamate J
- Journal Title
  
  Histology and Histopathology
  
  Volume: 29 Pages: 497-511
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26292152
[Journal Article] Nestin expression in remodeling of α-naphthylisothiocyanate (ANIT)-induced acute bile duct injury in rats2014
- Author(s)
  Golbar HM, Izawa T, Wijesundera KK, Tennakoon AH, Katou-Ichikawa C, Tanaka M, Kuwamura M, Yamate J
- Journal Title
  
  Journal of Comparative Pathology
  
  Volume: 151 Issue: 2-3 Pages: 255-263
- DOI
  10.1016/j.jcpa.2014.05.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26292152
[Journal Article] Rat hair follicle-constituting cells labeled by a newly-developed somatic stem cell-recognizing antibody: a possible marker of hair follicle development.2013
- Author(s)
  Ichikawa C, Izawa T, Juniantito V, Tanaka M, Hori M, Tanaka K, Takenaka S, Kuwamura M, Yamate J.
- Journal Title
  
  Histol Histopathol.
  
  Volume: 28 Pages: 257-268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23658265
[Journal Article] Immunohistochemical characterization of macrophages and myofibroblasts in fibrotic liver lesions due to fasciola infection in cattle2013
- Author(s)
  Golbar, H.M., Izawa, T., Juniantito, V., Ichikawa, C., Tanaka, M., Kuwamura, M., Yamate, J.
- Journal Title
  
  J Vet Med Sci
  
  Volume: 75 Pages: 857-865
- NAID
  130003362151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380173
[Journal Article] Immunophenotypical analysis of myofibroblasts and mesenchymal cells in the bleomycin-induced rat scleroderma, with particular reference to their origin.2013
- Author(s)
  Juniantito V, Izawa T, Yuasa T, Ichikawa C, Tanaka M, Kuwamura M, Yamate J
- Journal Title
  
  Exp Toxicol Pathol
  
  Volume: 65 Pages: 567-577
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380173
[Journal Article] Characterization of glial fibrillary acidic protein (GFAP)-expressing hepatic stellate cells and myofibroblasts in thioacetamide (TAA)-induced rat liver injury2013
- Author(s)
  Tennakoon AH, Izawa T, Wijesundera KK, Golbar HM, Tanaka M, Ichikawa C, Kuwamura M, Yamate J
- Journal Title
  
  Exp Toxicol Pathol
  
  Volume: 65(7-8) Pages: 1159-1171
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24780288
[Journal Article] Thy-1 expression, a possible marker of early myofibroblast development, in renal tubulointerstitial fibrosis induced in rats by cisplatin2013
- Author(s)
  Yuasa, T., Juniantito, V., Ichikawa, C., Yano, R., Izawa, T., Kuwamura, M., Yamate, J
- Journal Title
  
  Exp Toxicol Pathol
  
  Volume: 65 Issue: 5 Pages: 651-659
- DOI
  10.1016/j.etp.2012.07.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380173, KAKENHI-PROJECT-23658265
[Journal Article] Rat hair follicle-constituting cells labeled by a newly-developed somatic stem cell-recognizing antibody : a possible marker of hair follicle development2013
- Author(s)
  Ichikawa, C., Izawa, T., Juniantito, V., Tanaka, M., Hori, M., Tanaka, K., Takenaka, S., Kuwamura, M., Yamate, J
- Journal Title
  
  Histol Histopathol
  
  Volume: 28 Pages: 257-268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23658265
[Journal Article] Immunophenotypical characterization of macrophages in rat bleomycin-induced scleroderma2013
- Author(s)
  Juniantito, V., Izawa, T., Yuasa, T., Ichikawa, C., Yano, R., Kuwamura, M., Yamate, J
- Journal Title
  
  Vet Pathol
  
  Volume: 50 Issue: 1 Pages: 76-85
- DOI
  10.1177/0300985812450718
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380173
[Journal Article] Characterization of glial fibrillary acidic protein (GFAP)-expressing hepatic stellate cells and myofibroblasts in thioacetamide (TAA)-induced rat liver injury2013
- Author(s)
  Tennakoon, A.H., Izawa, T., Wijesundera, K.K., Golbar, H.M., Tanaka, M., Ichikawa, C., Kuwamura, M., Yamate, J.
- Journal Title
  
  Exp Toxicol Pathol
  
  Volume: 65 Issue: 7-8 Pages: 1159-1171
- DOI
  10.1016/j.etp.2013.05.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380173, KAKENHI-PROJECT-23658265
[Journal Article] Expressions of Iba1 and galectin-3 (Gal-3) in thioacetamide (TAA)-induced acute rat liver lesions2013
- Author(s)
  Wijesundera KK, Juniantito V, Golbar HM, Fujisawa K, Tanaka M, Ichikawa C, Izawa T, Kuwamura M, Yamate J
- Journal Title
  
  Exp Toxicol Pathol
  
  Volume: 65(6) Pages: 799-808
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24780288
[Journal Article] Immunophenotypical characterization of macrophages in rat bleomycin-induced scleroderma.2013
- Author(s)
  Juniantito V, Izawa T, Yuasa T, Ichikawa C, Yano R, Kuwamura M, Yamate J.
- Journal Title
  
  Vet Pathol
  
  Volume: 50 Pages: 76-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380173
[Journal Article] Slowly progressive cholangiofibrosis induced in rats by α-naphthylisothiocyanate (ANIT), with particular references to characteristics of macrophages and myofibroblasts.2013
- Author(s)
  Golbar HM, Izawa T, Ichikawa C, Tanaka M, Juniantito V, Sawamoto O, Kuwamura M, Yamate J.
- Journal Title
  
  Exp Toxicol Pathol.
  
  Volume: 65 Issue: 6 Pages: 825-835
- DOI
  10.1016/j.etp.2012.12.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23658265
[Journal Article] Expressions of Ibal and galectin-3 (Gal-3) in thioacetamide (TAA)-inducedacute rat liver lesions2013
- Author(s)
  Wijesundera KK, et al.
- Journal Title
  
  Exp Toxicol Pathol
  
  Volume: 65 Issue: 6 Pages: 799-808
- DOI
  10.1016/j.etp.2012.11.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12F02095, KAKENHI-PROJECT-22380173
[Journal Article] Distribution of cells labelled by a novel somatic stem cell-recognizing antibody (A3) in pulmonary genesis and bleomycin induced pulmonary fibrosis in rats2013
- Author(s)
  Hori, M., Juniantito, V., Izawa, T., Ichikawa, C., Tanaka, M., Tanaka, K., Takenaka, S., Kuwamura, M., Yamate, J
- Journal Title
  
  J Comp Pathol
  
  Volume: 148 Issue: 4 Pages: 385-395
- DOI
  10.1016/j.jcpa.2012.09.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380173, KAKENHI-PROJECT-23658265
[Journal Article] Immunophenotypical analysis of myofibroblasts and mesenchymal cells in the bleomycin-induced rat scleroderma, with particular reference to their origin2013
- Author(s)
  Juniantito, V., Izawa, T., Yuasa, T., Ichikawa, C., Tanaka, M., Kuwamura, M., Yamate, J
- Journal Title
  
  Exp Toxicol Pathol
  
  Volume: 65 Issue: 5 Pages: 567-577
- DOI
  10.1016/j.etp.2012.05.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380173, KAKENHI-PROJECT-23658265
[Journal Article] Thy-1 expression, a possible marker of early myofibroblast development, in renal tubulointerstitial fibrosis induced in rats by cisplatin.2013
- Author(s)
  Yuasa T, Juniantito V, Ichikawa C, Yano R, Izawa T, Kuwamura M, Yamate J.
- Journal Title
  
  Exp Toxicol Pathol
  
  Volume: 65 Pages: 651-659
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380173
[Journal Article] Molecular mechanisms of fibrosis-associated promotion of liver carcinogenesis2013
- Author(s)
  Uehara T, Ainslie GR, Kutanzi K, Pogribny IP, Muskhelishvili L, Izawa T, Yamate J, Kosyk O, Shymonyak S, Bradford BU, Boorman GA, Bataller R, Rusyn I
- Journal Title
  
  Toxicol Sci
  
  Volume: 132(1) Pages: 53-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24780288
[Journal Article] Inflammatory regulation of iron metabolism during thioacetamide-induced acute liver injury in rats2013
- Author(s)
  Izawa T, Murakami H, Wijesundera KK, Golbar HM, Kuwamura M, Yamate J
- Journal Title
  
  Exp Toxicol Pathol
  
  Volume: 66(2-3) Pages: 155-162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24780288
[Journal Article] Thy-1 expression, a possible marker of early myofibroblast development, in renal tubulointerstitial fibrosis induced in rats by cisplatin.2012
- Author(s)
  Yuasa T, Juniantito V, Ichikawa C, Yano R, Izawa T, Kuwamura M, Yamate J.
- Journal Title
  
  Exp Toxicol Pathol.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23658265
[Journal Article] Distribution of Cells Labelled by a Novel Somatic Stem Cell-recognizing Antibody (A3) in Pulmonary Genesis and Bleomycin induced Pulmonary Fibrosis in Rats.2012
- Author(s)
  Hori M, Juniantito V, Izawa T, Ichikawa C, Tanaka M, Tanaka K, Takenaka S, Kuwamura M, Yamate J.
- Journal Title
  
  J Comp Pathol.
  
  Volume: 147 Pages: 1-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23658265
[Journal Article] Immunophenotypical analyses of myofibroblasts in rat excisional wound healing : possible transdifferentiation of blood vessel pericytes and perifollicular dermal sheath cells into myofibroblasts2012
- Author(s)
  Juniantito, V., Izawa, T., Yuasa, T., Ichikawa, C., Yamamoto, E., Kuwamura, M., Yamate, J
- Journal Title
  
  Histol Histopathol
  
  Volume: 27 Pages: 515-527
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380173
[Journal Article] Amelioration of cisplatin-induced rat renal lesions by a cyclooxygenase (COX)-2 selective inhibitor2012
- Author(s)
  Yamamato, E., Izawa, T., Sawamoto, O., Juniantito, V., Kuwamura, M., Yamate, J
- Journal Title
  
  Exp Toxicol Pathol
  
  Volume: 64 Issue: 6 Pages: 625-631
- DOI
  10.1016/j.etp.2010.12.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23658265
[Journal Article] Immunohistochemical analyses of the kinetics and distribution of macrophages, hepatic stellate cells and bile duct epithelia in the developing rat liver2012
- Author(s)
  Golbar, H.M., Izawa, T., Murai, F., Kuwamura, M., Yamate, J
- Journal Title
  
  Exp Toxicol Pathol
  
  Volume: 64 Issue: 1-2 Pages: 1-8
- DOI
  10.1016/j.etp.2010.05.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380173, KAKENHI-PROJECT-23658265
[Journal Article] Immunophenotypical analyses of myofibroblasts in rat excisional wound healing : possible transdifferentiation of blood vessel pericytes and perifollicular dermal sheath cells into myofibroblasts2012
- Author(s)
  Juniantito, V., Izawa, T., Yuasa, T., Ichikawa, C., Yamamoto, E., Kuwamura, M., Yamate, J
- Journal Title
  
  Histol Histopathol
  
  Volume: 27 Pages: 515-527
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23658265
[Journal Article] Relationship of heat shock protein 25 with reactive macrophages in thioacetamide-induced rat liver injury2011
- Author(s)
  Fujisawa, K., Miyoshi, T., Tonomura, Y., Izawa, T., Kuwamura, M., Torii, M., Yamate, J
- Journal Title
  
  Exp Toxicol Pathol
  
  Volume: 63 Issue: 6 Pages: 599-605
- DOI
  10.1016/j.etp.2010.04.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380173
[Journal Article] Encapsulating peritoneal sclerosis associated with abnormal liver development in a young dog2011
- Author(s)
  Izawa T, Murai F, Akiyoshi H, Ohashi F, Yamate J, Kuwamura M.
- Journal Title
  
  The Journal of Veterinary Medical Science
  
  Volume: 73(5) Pages: 697-700
- NAID
  130000444792
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22880029
[Journal Article] Heterogeneity of macrophage populations and expression of galectin-3 in cutaneous wound healing in rats2011
- Author(s)
  Juniantito, V., Izawa, T., Yamamoto, E., Murai, F., Kuwamura, M., Yamate, J
- Journal Title
  
  J Comp Pathol
  
  Volume: 145 Issue: 4 Pages: 378-389
- DOI
  10.1016/j.jcpa.2011.01.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380173
[Journal Article] Encapsulating peritoneal sclerosis associated with abnormal liver development in a young dog2011
- Author(s)
  Izawa T, et al
- Journal Title
  
  The Journal of veterinary medical science
  
  Volume: 73 Pages: 697-700
- NAID
  130000444792
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22880029
[Journal Article] Immunohistochemical characterization of macrophages and myofibroblasts in alpha-Naphthylisothiocyanate (ANIT)-induced bile duct injury and subsequent fibrogenesis in rats2011
- Author(s)
  Golbar, H.M., Izawa, T., Yano, R., Ichikawa, C., Sawamoto, O., Kuwamura, M., LaMarre, J., Yamate, J
- Journal Title
  
  Toxicol Pathol
  
  Volume: 39 Issue: 5 Pages: 795-808
- DOI
  10.1177/0192623311413790
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380173
[Journal Article] Immunohistochemical Expressions of Main PGE<sub>2</sub> Biosynthesis-related Enzymes and PGE<sub>2</sub> Receptor in Rat Nephrogenesis2011
- Author(s)
  Yamamoto, E., Izawa, T., Kuwamura, M., Yamate, J
- Journal Title
  
  Journal of Toxicologic Pathology
  
  Volume: 24 Issue: 4 Pages: 257-261
- DOI
  10.1293/tox.24.257
- NAID
  130001884731
- ISSN
  0914-9198, 1881-915X
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380173
[Journal Article] Relationship of Cell Proliferating Marker Expressions with PGE2 Receptors in Regenerating Rat Renal Tubules after Cisplatin Injection2010
- Author(s)
  Yamamoto, E., Izawa, T., Juniantito, V., Kuwamura, M., Yamate, J
- Journal Title
  
  Journal of Toxicologic Pathology
  
  Volume: 23 Issue: 4 Pages: 271-275
- DOI
  10.1293/tox.23.271
- NAID
  130000450753
- ISSN
  0914-9198, 1881-915X
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380173
[Journal Article] Thy-1 Expressing Mesenchymal Cells in Rat Nephrogenesis in Correlation with Cells Immunoreactive for .ALPHA.-Smooth Muscle Actin and Vimentin2010
- Author(s)
  Yuasa, T., Izawa, T., Kuwamura, M., Yamate, J
- Journal Title
  
  Journal of Toxicologic Pathology
  
  Volume: 23 Issue: 1 Pages: 1-10
- DOI
  10.1293/tox.23.1
- NAID
  130000262636
- ISSN
  0914-9198, 1881-915X
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380173
[Journal Article] Involvement of endogenous prostaglandin E2 in tubular epithelial regeneration through inhibition of apoptosis and epithelial-mesenchymal transition in cisplatin-induced rat renal lesions2010
- Author(s)
  Yamamoto, E., Izawa, T., Juniantito, V., Kuwamura, M., Sugiura, K., Takeuchi, T., Yamate, J
- Journal Title
  
  Histol Histopathol
  
  Volume: 25 Pages: 995-1007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380173
[Journal Article] Abnormal iron accumulation is involved in the pathogenesis of the demyelinating dmy rat but not in the hypomyelinating mv rat2010
- Author(s)
  Izawa T, et al
- Journal Title
  
  Brain Research
  
  Volume: 1349 Pages: 105-114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22880029
[Journal Article] The kinetics and distribution of different macrophage populations in the developing rat skin2010
- Author(s)
  Juniantito, V., Izawa, T., Yamamoto, E., Kuwamura, M., Yamate, J
- Journal Title
  
  Histol Histopathol
  
  Volume: 25 Pages: 985-994
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380173
[Journal Article] Abnormal iron accumulation is involved in the pathogenesis of the demyelinating dmy rat but not in the hypomyelinating mv rat2010
- Author(s)
  Izawa T, Yamate J, Franklin RJ, Kuwamura M.
- Journal Title
  
  Brain Research
  
  Volume: 1349 Pages: 105-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22880029
[Presentation] AI画像解析による肝毒性所見の定量化と血清ALT、ASTとの相関解析2023
- Author(s)
  稲井洋平、井澤武史、瓶井知美、田中美有、山手丈至、桑村充
- Organizer
  第39回日本毒性病理学会総会及び学術集会
- Data Source
  KAKENHI-PROJECT-19H03130
[Presentation] Application of chimeric mouse with humanized liver in pathological research2023
- Author(s)
  Izawa T
- Organizer
  The 10th ASVP and 10th JCVP Joint Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06415
[Presentation] Influence of vitamin K on bleeding tendency in rats fed high-iron diets2022
- Author(s)
  Inai Y, Izawa T, Fujiwara S, Tanaka M, Kuwamura M
- Organizer
  The 38th Annual Meeting of the Japanese Society of Toxicologic Pathology and the 1st Meeting of the Asian Union of Toxicologic Pathology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06415
[Presentation] AI画像解析による肝毒性所見の定量化と血清ALT, ASTとの相関解析2022
- Author(s)
  稲井洋平，井澤武史，瓶井知美，田中美有，山手丈至，桑村充
- Organizer
  第39回日本毒性病理学会学術集会
- Data Source
  KAKENHI-PROJECT-20K06415
[Presentation] 鉄過剰による化合物誘発肝硬変の抑制に関わる転写因子 Nrf2の役割2022
- Author(s)
  濱田菜々子，井澤武史，新真智，瓶井知美，藤原奨，田中美有，田口恵子，山本雅之，桑村充
- Organizer
  第165回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-20K06415
[Presentation] Influence of diabetes induction on rat NAFLD model2022
- Author(s)
  Izawa T, Mizuguchi E, Yamate J, Kuwamura M
- Organizer
  The 38th Annual Meeting of the Japanese Society of Toxicologic Pathology and the 1st Meeting of the Asian Union of Toxicologic Pathology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06415
[Presentation] ヒト成長ホルモン処置による脂肪肝抑制がヒト肝細胞キメラマウスの肝毒性感受性へ及ぼす影響の検討2022
- Author(s)
  瓶井知美，井澤武史，高見優生，田中美有，桑村充
- Organizer
  第39回日本毒性病理学会学術集会
- Data Source
  KAKENHI-PROJECT-20K06415
[Presentation] 鉄過剰による薬物性肝障害の修飾に関わるオートファジーの解析2021
- Author(s)
  藤原奨，井澤武史，相川諒，桑村充，山手丈至
- Organizer
  第164回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03130
[Presentation] ラット脂肪肝-肝腫瘍モデルにおける食餌性鉄過剰の病態修飾2021
- Author(s)
  新真智，井澤武史，水口恵理，桑村充，山手丈至
- Organizer
  第37回日本毒性病理学会学術集会
- Data Source
  KAKENHI-PROJECT-20K06415
[Presentation] 鉄過剰による薬物性肝障害の修飾に関わるオートファジーの解析2021
- Author(s)
  藤原奨，井澤武史，相川諒，桑村充，山手丈至
- Organizer
  第164回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-20K06415
[Presentation] 鉄過剰による化合物誘発肝障害の軽減メカニズムの解明2020
- Author(s)
  相川諒，井澤武史，森睦貴，稲井洋平，桑村充，山手丈至
- Organizer
  第163回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-20K06415
[Presentation] リポポリサッカライド投与を併用した代謝性肝疾患モデルの病態解析2020
- Author(s)
  水口恵理，井澤武史，新真智，桑村充，山手丈至
- Organizer
  第163回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-20K06415
[Presentation] 実験的鉄過剰による肝疾患の修飾多様性2019
- Author(s)
  井澤武史，新真智，稲井洋平，森睦貴，桑村充，山手丈至
- Organizer
  第43回日本鉄バイオサイエンス学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08084
[Presentation] チオアセトアミド誘発ラット急性肝障害モデルの好中球・マクロファーシ誘導における炎症誘導因子の役割の解明2019
- Author(s)
  倉持瑞樹，井澤武史，Rahman N，桑村充，山手丈至
- Organizer
  第35回日本毒性病理学会学術集会（東京都江戸川区）
- Data Source
  KAKENHI-PROJECT-19H03130
[Presentation] 「DAMPs-オートファジー-肝マクロファージ」の相互作用に基づいたLPSの肝機能への影響2019
- Author(s)
  高見優生，倉持瑞樹，井澤武史，桑村充，山手丈至
- Organizer
  第162回日本獣医学会学術集会（茨城県つくば市）
- Data Source
  KAKENHI-PROJECT-19H03130
[Presentation] カナバン病モデルAspaKOラットの視神経の病態解析2019
- Author(s)
  森山裕至，井澤武史，庫本高志，山手丈至，桑村　充
- Organizer
  第6回日本獣医病理学専門家協会学術集会
- Data Source
  KAKENHI-PROJECT-15H04595
[Presentation] Participation of heterogeneous macrophages related to M1/M2 types in D-galactosamine-induced acute rat liver injury2019
- Author(s)
  Rahman N，Pervin M，倉持瑞樹，Karim M，井澤武史，桑村充，山手丈至
- Organizer
  第35回日本毒性病理学会学術集会（東京都江戸川区）．
- Data Source
  KAKENHI-PROJECT-19H03130
[Presentation] Altered susceptibility to acetaminophen-induced liver injury in mouse model of nonalcoholic fatty liver disease.2019
- Author(s)
  Izawa, T., Cortes, R., Gadupudi, G., Ramesh, K., Clayton, N., Herbert, R., Wilson, R., Brar, S., Cora, M., Travlos, G., Flagler, N., Sills, R., Pandiri, A.
- Organizer
  2019 STP (Society of Toxicologic Pathology) 38th Annual Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KK0158
[Presentation] 非アルコール性脂肪性肝疾患（NAFLD）モデルラットにおける鉄過剰の病態修飾機序の解明2019
- Author(s)
  藤原咲春，井澤武史，森睦貴，新真智，桑村充，山手丈至
- Organizer
  第162回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08084
[Presentation] 鉄過剰による化合物誘発性肝障害の部位特異的修飾メカニズムの解析2018
- Author(s)
  森　睦貴，井澤武史，稲井洋平，新　真智，桑村　充，山手丈至
- Organizer
  第161回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08084
[Presentation] 炎症誘導因子(DAMPs)と関連シグ;ナルを介したチオアセトアミト（TAA)誘発ラット急性肝障害における進展機序の解析．2018
- Author(s)
  倉持瑞樹，井澤武史，Pervin M，Karim MR，桑村　充，山手丈至．
- Organizer
  第34回日本毒性病理学会学術集会（沖縄県那覇市）．2018年1月25日・26日．
- Data Source
  KAKENHI-PROJECT-26292152
[Presentation] 非アルコール性脂肪性肝炎モデルラットの肝炎進展に関わる全身免疫の役割2018
- Author(s)
  井澤武史，大地祥子，新　真智，宮城伶奈，橋本　愛，桑村　充，山手丈至
- Organizer
  第34回日本毒性病理学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08084
[Presentation] Time dependent cytoprotective phenomenon of lipopolysaccharide in TAA-induced acute liver injury in rats2018
- Author(s)
  Karim MR，Pervin M，倉持瑞樹，井澤武史，桑村　充，山手丈至．
- Organizer
  第34回日本毒性病理学会学術集会（沖縄県那覇市）．2018年1月25日・;26日．
- Data Source
  KAKENHI-PROJECT-26292152
[Presentation] Analysis of hemorrhagic diathesis in rats fed a high-iron diet2018
- Author(s)
  Izawa T, Mori M, Atarashi M, Tsuchiya S, Kuwamura M, Yamate J
- Organizer
  STP (Society of Toxicologic Pathology) 37th Annual Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08084
[Presentation] 1.Damage-Associated Molecular Patterns (DAMPs) and MHC class II-expressing Cells in Thioacetamide (TAA)-Induced Rat Liver Injury.2017
- Author(s)
  Kuramochi M, Izawa T, Pervin M, Bondoc A, Karim MR, Kuwamura M, Yamate J.
- Organizer
  STP (Society of Toxicologic Pathology) 36th Annual Symposium (Montreal, Canada). 24th-29th, June, 2017.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26292152
[Presentation] カナバン病モデルAspaノックアウトラットの病態解析2017
- Author(s)
  星合里香，井澤武史，山手丈至，西谷あい，田中美有，庫本高志，桑村　充
- Organizer
  第136回関西実験動物研究会
- Data Source
  KAKENHI-PROJECT-15H04595
[Presentation] M1/M2分極化に基づいたイソプロテレノール誘発ラット心筋傷害におけるマクロファージの特性解析．2017
- Author(s)
  古賀真昭，Karim MR，倉持瑞樹，井澤武史，桑村　充，山手丈至．
- Organizer
  第33回日本毒性病理学会学術集会
- Place of Presentation
  堺市
- Year and Date
  2017-01-26
- Data Source
  KAKENHI-PROJECT-26292152
[Presentation] チオアセトアミド反復投与ラット肝障害モデルにおける肝細胞傷害の軽減効果の解析．2017
- Author(s)
  倉持瑞樹，井澤武史，Pervin M，Karim MR，Bondoc A，桑村　充，山手丈至．
- Organizer
  第33回日本毒性病理学会学術集会
- Place of Presentation
  堺市
- Year and Date
  2017-01-26
- Data Source
  KAKENHI-PROJECT-26292152
[Presentation] 高脂肪食誘発性肝疾患に対するラットの週齢感受性の解析2017
- Author(s)
  大地祥子，稲井洋平，井澤武史，桑村　充，山手丈至
- Organizer
  第160回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08084
[Presentation] Lipopolysaccharide-mediated autophagy protects against thioacetamide-induced acute liver injury in rats.2017
- Author(s)
  2.Karim MR, Pervin M, Kuramochi M, Izawa T, Kuwamura M, Yamate J.
- Organizer
  STP (Society of Toxicologic Pathology) 36th Annual Symposium (Montreal, Canada). 24th-29th, June, 2017.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26292152
[Presentation] デキストラン硫酸ナトリウム(DSS)誘発ラット結腸病変における体性幹細胞認識抗体A3 陽性細胞の動態．2017
- Author(s)
  仁科嘉修，市川(加藤)智彩，倉持瑞樹，井澤武史，桑村　充，山手丈至．
- Organizer
  第33回日本毒性病理学会学術集会
- Place of Presentation
  堺市
- Year and Date
  2017-01-26
- Data Source
  KAKENHI-PROJECT-26292152
[Presentation] ブチル二塩化スズ誘発ラット膵線維化におけるマクロファージ;と間葉系細胞の動態．2017
- Author(s)
  橋本　愛，Bondoc A，Karim MR，井澤武史，桑村　充，山手丈至．
- Organizer
  第33回日本毒性病理学会学術集会
- Place of Presentation
  堺市
- Year and Date
  2017-01-26
- Data Source
  KAKENHI-PROJECT-26292152
[Presentation] Effect of lipopolysaccaride on autophagy and autophagic response in liver homeostasis in rats．2017
- Author(s)
  Karim MR，Pervin M，井澤武史，桑村　充，山手丈至．
- Organizer
  第33回日本毒性病理学会学術集会
- Place of Presentation
  堺市
- Year and Date
  2017-01-26
- Data Source
  KAKENHI-PROJECT-26292152
[Presentation] 遺伝性ミエリン変性モデルVFラットの病態および原因遺伝子Dopey1の機能解析2017
- Author(s)
  安井　彩，田中美有，竹中重雄，井澤武史，山手丈至，桑村　充
- Organizer
  第136回関西実験動物研究会
- Data Source
  KAKENHI-PROJECT-15H04595
[Presentation] トリメチルスス誘発神経毒性ラットモデル;ルにおける血清 miRNA バイオマーカー探索．2017
- Author(s)
  緒方敬子，武田周二，串田昌彦，桑村　充，井澤武史，山手丈至．
- Organizer
  第33回日本毒性病理学会学術集会
- Place of Presentation
  堺市
- Year and Date
  2017-01-26
- Invited
- Data Source
  KAKENHI-PROJECT-26292152
[Presentation] 腸管の発生と線維化における幹細胞認識抗体（A3）標識細胞の動態．2016
- Author(s)
  仁科嘉修，市川（加藤）智彩，倉持瑞樹，井澤武史，桑村　充，山手丈至．
- Organizer
  第159回日本獣医学会学術集会
- Place of Presentation
  藤沢市
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-26292152
[Presentation] チオアセトアミド誘発ラット肝障害における障害誘導因子とMHCクラスII発現細胞の特性．2016
- Author(s)
  倉持瑞樹，井澤武史，Pervin M，Bondoc A，桑村　充，山手丈至．
- Organizer
  第32回日本毒性病理学会学術集会
- Place of Presentation
  サンアポート高松・かがわ国際会議場（香川県高松）
- Year and Date
  2016-01-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26292152
[Presentation] 2.Pathogenic Role and Regulation of Galectin-3 Expression in Renal Fibrosis and TGF-beta 1 Induced Fibrogenesis.2015
- Author(s)
  Juniantito V, Izawa T, Kuwamura M, Priosoeryanto BP, Harlina E, Yamate J
- Organizer
  ACVP/ASVCP/STP Combined Annual Meeting.
- Place of Presentation
  Minneapolis Convention Center (Minneapolis, USA)
- Year and Date
  2015-10-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26292152
[Presentation] Histological and ultrastructural studies on the Canavan disease model rat2015
- Author(s)
  Kuwamura M, Tanimura S, Tanaka M, Izawa T, Kuramoto T, Yamate J
- Organizer
  Combined Annual Meeting of ACVP, ASVCP and STP
- Place of Presentation
  ミネアポリスコンベンションセンター，ミネアポリス，米国
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04595
[Presentation] ミエリン異常ミュータントラットの病態比較2015
- Author(s)
  谷村聡美，田中美有，竹中重雄，井澤武史，庫本高志，山手丈至，桑村　充
- Organizer
  第128回関西実験動物研究会
- Place of Presentation
  京都大学楽友会，京都市左京区
- Year and Date
  2015-12-04
- Data Source
  KAKENHI-PROJECT-15H04595
[Presentation] 複合型高脂肪食投与によるラット肝病変の比較検討2015
- Author(s)
  井澤武史，宮城伶奈，橋本　愛，新　真智，桑村　充，山手丈至
- Organizer
  第42回日本毒性学会学術年会
- Place of Presentation
  石川県立音楽堂（石川県金沢市）
- Year and Date
  2015-06-29
- Data Source
  KAKENHI-PROJECT-26850184
[Presentation] Dietary iron overload alters hepatic inflammation in a rat model of nonalcoholic steatohepatitis2015
- Author(s)
  Izawa T, Atarashi M, Miyagi R, Kuwamura M, Yamate J
- Organizer
  2015 ACVP/ASVCP/STP Combined Annual Meeting
- Place of Presentation
  Minneapolis Convention Center, Minneapolis, USA
- Year and Date
  2015-10-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26850184
[Presentation] 肝硬変における鉄過剰の病理学的役割の解析2015
- Author(s)
  新　真智，井澤武史，桑村　充，山手丈至
- Organizer
  第158回日本獣医学会学術集会
- Place of Presentation
  北里大学（青森県十和田市）
- Year and Date
  2015-09-07
- Data Source
  KAKENHI-PROJECT-26850184
[Presentation] ラット発生過程の膵とイヌの線維化膵における膵星細胞と筋線維芽細胞の免疫組織学的特性解析2014
- Author(s)
  橋本　愛，井澤武史，田中美有，Golbar Hossain M，Kavindra Wijesundera，桑村充，山手丈至
- Organizer
  第30回日本毒性病理学会学術集会
- Place of Presentation
  徳島
- Invited
- Data Source
  KAKENHI-PROJECT-22380173
[Presentation] 食餌性鉄過剰・鉄欠乏によるラット肝臓の病理学的変化2014
- Author(s)
  井澤武史,宮城伶奈,堀内貴至,桑村充,山手丈至
- Organizer
  第30回日本毒性病理学会学術集会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-24780288
[Presentation] ラット発生過程の膵とイヌの線維化膵における膵星細胞と筋線維芽細胞の免疫組織学的特性解析2014
- Author(s)
  橋本愛, 井澤武史, 田中美有, Golbar HM, Wijesundera K, 桑村充, 山手丈至
- Organizer
  第30回日本毒性病理学会学術集会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-23658265
[Presentation] Characterization of hepatic stellate cells (HSCs) in terms of epithelial-mesenchymal transition in normal and cirrhotic rat livers2014
- Author(s)
  AnushaTENNAKOON, Takeshi IZAWA, Kavindra WIJESUNDERA, Hossain M. Golbar, MiyuuTANAKA, Mitsuru KUWAMURA and Jyoji YAMATE
- Organizer
  第30回日本毒性病理学会学術集会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-23658265
[Presentation] 正常肝と肝硬変ラットにおける上皮-間葉転換の観点からの肝星細胞の特徴解析2014
- Author(s)
  Tennakoon A, 井澤武史, Wijesundera K, Golbar HM,田中美有, 桑村充, 山手丈至
- Organizer
  第30回日本毒性病理学会学術集会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-22380173
[Presentation] 正常肝と肝硬変ラットにおける上皮-間葉転換の観点からの肝星細胞の特徴解析2014
- Author(s)
  Tennakoon A, 井澤武史, Wijesundera K, Golbar HM, 田中美有, 桑村充, 山手丈至
- Organizer
  第30回日本毒性病理学会学術集会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-23658265
[Presentation] Participation of macrophage populations in GST-P-positive liver lesions induced in rats by repeated injections of thioacetamide (TAA)2013
- Author(s)
  Wijesundera K, Izawa T, Katou-Ichikawa C, Tennakoon A, Murakami H, Golbar H, Kuwamura M, and Yamate J
- Organizer
  ACVP & ASVCP 2013 Concurrent Annual Meeting
- Place of Presentation
  Montreal, Canada
- Data Source
  KAKENHI-PROJECT-22380173
[Presentation] 肝硬変の進展に関わる新規miRNAの病理学的役割の検討2013
- Author(s)
  堀内貴至，井澤武史，Wijesundera K，桑村　充，山手丈至
- Organizer
  第156回日本獣医学会学術集会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-24780288
[Presentation] Different macrophage populations in GST-P-positive/negative rat liver lesions2013
- Author(s)
  Kavindra WIJESUNDERA, Takeshi IZAWA, Chisa ICHIKAWA, Anusha TENNAKOON, Hiroshi MURAKAMI, Hossain M. GOLBAR, Mitsuru KUWAMURA, Jyoji YAMATE
- Organizer
  The 64th Annual Meeting　of American College of Veterinary Pathologists
- Place of Presentation
  カナダ　モントリオール
- Invited
- Data Source
  KAKENHI-PROJECT-22380173
[Presentation] α-naphthylisothiocyanate(ANIT)により誘発したラットの急性と慢性胆管病変におけるマクロファージと筋線維芽細胞の特性比較2013
- Author(s)
  Golbar HM, 井澤武史, 市川智彩, 田中美有, 桑村充, 山手丈至
- Organizer
  第29回日本毒性病理学会学術集会
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-22380173
[Presentation] 肝硬変の進展に関わる新規miRNAの病理学的役割の検討2013
- Author(s)
  堀内貴至,井澤武史,Wijesundera K,桑村充,山手丈至
- Organizer
  第30回日本毒性病理学会学術集会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-24780288
[Presentation] Different macrophage populations in pseudolobules (PLs) with or without adipophilin expression in thioacetamide (TAA)-induced rat cirrhosis2013
- Author(s)
  Wijesundera K, 井澤武史, Tennakoon A, 藤智彩, Golbar HM, 桑村充, 山手丈至
- Organizer
  第156回日本獣医学会学術集会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-22380173
[Presentation] イヌの肝・胆道系疾患の傾向とその病理学的特徴2013
- Author(s)
  堀内貴至,井澤武史,井澤敬子,桑村充,山手丈至
- Organizer
  第155回日本獣医学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24780288
[Presentation] Characterization of GFAP-expressing hepatic stellate cells (HSCs) and myofibroblasts (MFs) in thioacetamide (TAA)-induced rat liver injury2013
- Author(s)
  Tennakoon A, 井澤武史, Wijesundera K, 村上宙, Golbar HM, 田中美有, 市川智彩, 桑村充, 山手丈至
- Organizer
  第155回日本獣医学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23658265
[Presentation] シスプラチン誘発ラット腎線維化におけるマクロファージの機能特性の解析2013
- Author(s)
  松山聡, 井澤武史, 桑村充, 山手丈至
- Organizer
  第156回日本獣医学会学術集会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-22380173
[Presentation] ラット悪性線維性組織球腫（MFH）由来の異なるクローン細胞株（MT-8とMT-9）の免疫組織化学的及び網羅的遺伝子解析2013
- Author(s)
  小寺喬、市川智彩、Tennakoon Anusha、井澤武史、桑村充、越智誠支、山手丈至
- Organizer
  第29回日本毒性病理学会
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-23658265
[Presentation] シスプラチン誘発ラット急性腎障害モデルにおけるバイオマーカーの発現動態2012
- Author(s)
  山本絵美, 増野功一, 藤澤可恵, 土屋紀子, 松嶋周一, 高須伸夫, 鳥井幹則, 井澤武史, 桑村充, 山手丈至
- Organizer
  第28回日本毒性病理学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22380173
[Presentation] ラット体性幹細胞標識抗体A3 が認識する毛発生過程における上皮細胞の特性解明2012
- Author(s)
  市川智彩, 井澤武史, 田中勝啓, 竹中重雄, 桑村充, 山手丈至
- Organizer
  第154回日本獣医学会学術集会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-23658265
[Presentation] シスプラチン誘発ラット腎間質線維化におけるカルポニンの発現と筋線維芽細胞との関連2012
- Author(s)
  湯浅隆弘, 井澤武史, 桑村充, 山手丈至
- Organizer
  第28回日本毒性病理学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23658265
[Presentation] ラット体性幹細胞標識抗体A3が認識する毛発生過程における上皮細胞の特性解明 .2012
- Author(s)
  市川智彩、井澤武史、田中勝啓、竹中重雄、桑村充、山手丈至
- Organizer
  第154回日本獣医学会学術集会
- Place of Presentation
  岩手
- Data Source
  KAKENHI-PROJECT-23658265
[Presentation] シスプラチン（CDDP）誘発ラット腎障害モデルでの再生尿細管におけるβ-カテニンの発現2012
- Author(s)
  寺田直美、市川智彩、井澤武史、桑村充、山手丈至
- Organizer
  第154回日本獣医学会学術集会
- Place of Presentation
  岩手
- Data Source
  KAKENHI-PROJECT-23658265
[Presentation] ラット肝硬変モデルにおける鉄代謝障害の分子メカニズムの解明．2012
- Author(s)
  村上　宙，井澤武史，Wijesundera K，Golbar HM，Tennakoon A，桑村　充，山手丈至．
- Organizer
  第154回日本獣医学会学術集会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-24780288
[Presentation] Thioacetamide誘発ラット急性肝障害における鉄調節因子群の発現プロファイリング2012
- Author(s)
  井澤武史
- Organizer
  第28回日本毒性病理学会学術集会
- Place of Presentation
  東京
- Year and Date
  2012-02-03
- Data Source
  KAKENHI-PROJECT-22880029
[Presentation] ラット肝硬変モデルにおける鉄代謝障害の分子メカニズムの解明2012
- Author(s)
  村上宙,井澤武史,Wijesundera K,Golbar HM,Tennakoon A,桑村充,山手丈至
- Organizer
  第154回日本獣医学会学術集会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-24780288
[Presentation] シスプラチン誘発ラット腎間質線維化におけるカルポニンの発現と筋線維芽細胞との関連2012
- Author(s)
  湯浅隆弘, 井澤武史, 桑村充, 山手丈至
- Organizer
  第28回日本毒性病理学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22380173
[Presentation] M1/M2 macrophage polarization in thioacetamide (TAA)-induced acute rat liver lesions2012
- Author(s)
  Wijesundera K,Golbar HM,市川智彩, 田中美有, 井澤武史, 桑村充, 山手丈至
- Organizer
  第28回日本毒性病理学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22380173
[Presentation] シスプラチン誘発ラット腎障害モデルでの再生尿細管におけるβ-カテニンの発現2012
- Author(s)
  寺田直美, 市川智彩, 井澤武史, 桑村充, 山手丈至
- Organizer
  第154回日本獣医学会学術集会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-22380173
[Presentation] 四塩化炭素誘発肝病変におけるHeat shock protein 25 とAdipophilin の発現動態2011
- Author(s)
  藤澤可恵, 山本絵美, 増野功一, 土屋紀子,松嶋周一, 高須伸夫, 井澤武史, 桑村充, 鳥井幹則, 山手丈至
- Organizer
  第27回日本毒性病理学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22380173
[Presentation] Comparisons of properties of macrophages and myofibroblasts between two different cutaneous fibrosis rat models.Juniantito V2011
- Author(s)
  井澤武史, 矢野遼, 桑村充, 山手丈至
- Organizer
  第27回日本毒性病理学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22380173
[Presentation] Immunophenotypical properties of macrophages and myofibroblasts in fasciola-infested cirrhotic cattle liver2011
- Author(s)
  Golbar HM,井澤武史, 桑村充, 山手丈至
- Organizer
  第151回日本獣医学会学術集会
- Place of Presentation
  府中
- Data Source
  KAKENHI-PROJECT-22380173
[Presentation] Involvement of macrophages and myofibroblasts in chronic alpha-naphthyl isothiocyanate (ANIT)-induced peribiliary fibrosis in rat model2011
- Author(s)
  Golbar HM, 井澤武史, 矢野遼, 澤本修, 桑村充, 山手丈至
- Organizer
  第27回日本毒性病理学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23658265
[Presentation] Immunohistochemical characterization of macrophages and myofibroblasts in biliary cirrhosis due to liver fluke (Fasciola spp) infestation in cattle2011
- Author(s)
  Golbar HM, Juniantito V, Ichikawa C, Tanaka M, Izawa T, Kuwamura M, Yamate J
- Organizer
  The Joint Meeting of the 5th Conference and Congress of Asian Society of Veterinary Pathology (ASVP) 2011 and the 10th Scientific Symposium of Indonesia Society of Veterinary Pathology (ISVP) 2011
- Place of Presentation
  Bogor, Indonesia
- Data Source
  KAKENHI-PROJECT-22380173
[Presentation] Immunohistochemical detection of macrophages and myofibroblasts in rat model of bleomycin-induced scleroderma2011
- Author(s)
  Juniantito V, Ichikawa C, Izawa T, Kuwamura M, Yamate J
- Organizer
  The Joint Meeting of the 5th Conference and Congress of Asian Society of Veterinary Pathology (ASVP) 2011 and the 10th Scientific Symposium of Indonesia Society of Veterinary Pathology (ISVP) 2011
- Place of Presentation
  Bogor, Indonesia
- Data Source
  KAKENHI-PROJECT-22380173
[Presentation] Nestin expression in α-naphthylisocyanate (ANIT)-induced acute bile duct injury lesions in rats2011
- Author(s)
  Golbar HM, 井澤武史, 市川智彩, 田中美有, 桑村充, 山手丈至
- Organizer
  第152回日本獣医学会学術集会
- Place of Presentation
  堺
- Data Source
  KAKENHI-PROJECT-23658265
[Presentation] Involvement of macrophages and myofibroblasts in chronic ANIT-induced peribiliary fibrosis in rat model2011
- Author(s)
  Golbar HM, 井澤武史, 矢野遼, 澤本修, 桑村充, 山手丈至
- Organizer
  第27回日本毒性病理学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22380173
[Presentation] Immunohistochemical detection of macrophages and myofibroblasts in rat model of bleomycin-induced scleroderma2011
- Author(s)
  Juniantito V, Ichikawa C, Izawa T, Kuwamura M, Yamate J
- Organizer
  The Joint Meeting of the 5th Conference and Congress of Asian Society of Veterinary Pathology (ASVP) 2011 and the 10th Scientific Symposium of Indonesia Society of Veterinary Pathology (ISVP) 2011
- Place of Presentation
  Bogor, Indonesia
- Data Source
  KAKENHI-PROJECT-23658265
[Presentation] シスプラチン誘発ラット腎傷害における内因性PGE2 の影響2011
- Author(s)
  山本絵美, 増野功一, 藤澤可恵, 土屋紀子, 松嶋周一, 高須伸夫, 鳥井幹則, 井澤武史, Juniantito V, 桑村充, 杉浦喜久弥, 竹内正吉, 山手丈至
- Organizer
  第27回日本毒性病理学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23658265
[Presentation] Expression of Iba1 and galectin-3 (Gal-3) in thioacetamide (TAA)-induced acute rat liver lesions2011
- Author(s)
  Wijesundera K, Juniantito V,Golbar HM,藤澤可恵 ,田中美有, 市川智彩, 井澤武史 ,桑村充, 山手丈至
- Organizer
  第152回日本獣医学会学術集会
- Place of Presentation
  堺
- Data Source
  KAKENHI-PROJECT-22380173
[Presentation] Nestin expression in α-naphthylisocyanate (ANIT)-induced acute bile duct injury lesions in rats2011
- Author(s)
  Golbar HM,井澤武史, 市川智彩, 田中美有, 桑村充, 山手丈至
- Organizer
  第152回日本獣医学会学術集会
- Place of Presentation
  堺
- Data Source
  KAKENHI-PROJECT-22380173
[Presentation] ラット腎間質線維化におけるThy-1 免疫陽性細胞の動態, 特に筋線維芽細胞との関連について2011
- Author(s)
  湯浅隆弘, 井澤武史, 桑村充, 山手丈至
- Organizer
  第27回日本毒性病理学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23658265
[Presentation] Comparisons of properties of macrophages and myofibroblasts between two different cutaneous fibrosis rat models2011
- Author(s)
  Juniantito V, 井澤武史, 矢野遼, 桑村充, 山手丈至
- Organizer
  第27回日本毒性病理学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23658265
[Presentation] ラット腎間質線維化におけるThy-1 免疫陽性細胞の動態2011
- Author(s)
  湯浅隆弘, 井澤武史, 桑村充, 山手丈至
- Organizer
  第27回日本毒性病理学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22380173
[Presentation] シスプラチン誘発ラット腎傷害における内因性PGE2 の影響2011
- Author(s)
  山本絵美, 増野功一, 藤澤可恵, 土屋紀子, 松嶋周一, 高須伸夫, 鳥井幹則, 井澤武史, Juniantito V,桑村充, 杉浦喜久弥, 竹内正吉, 山手丈至
- Organizer
  第27回日本毒性病理学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22380173
[Presentation] Dysregulation of iron homeostasis during progression of thioacetamide-induced liver cirrhosis in rats
- Author(s)
  Izawa T, Murakami H, Miyagi R, Wijesundera K, Tennakoon A, Golbar HM, Kuwamura M, Yamate J
- Organizer
  STP 33rd Annual Symposium
- Place of Presentation
  Washington DC, USA
- Year and Date
  2014-06-22 – 2014-06-26
- Data Source
  KAKENHI-PROJECT-26850184
[Presentation] 非アルコール性脂肪性肝炎モデルラットの病理学的解析
- Author(s)
  宮城伶奈，井澤武史，橋本　愛，堀内貴至，田中美有，桑村　充，山手丈至
- Organizer
  第157回日本獣医学会学術集会
- Place of Presentation
  北海道大学（北海道札幌市）
- Year and Date
  2014-09-09 – 2014-09-10
- Data Source
  KAKENHI-PROJECT-26850184
[Presentation] Characterization of repopulating macrophages in liver after depletion with liposomal clodronate in rats.
- Author(s)
  M. Pervin, H. M. Golbar, B. Alexandra, M. Uemura, T. Izawa, M. Kuwamura and J. Yamate
- Organizer
  第157回日本獣医学会学術集会
- Place of Presentation
  北海道大学、札幌
- Year and Date
  2014-09-09 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-26292152
[Presentation] Characterization of repopulating macrophages in liver after depletion with liposomal clodronate in rats
- Author(s)
  Pervin M，Golbar HM，Bondoc A，植村明都，井澤武史，桑村　充，山手丈至
- Organizer
  第31回日本毒性病理学会学術集会
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Year and Date
  2015-01-29 – 2015-01-30
- Data Source
  KAKENHI-PROJECT-26850184
[Presentation] Analyses of hepatic macrophages depleted by clodoronate in rat liver.
- Author(s)
  M. Pervin, H. M. Golbar, B. Alexandra, K. K. Wijesundera, T. Izawa, M. Kuwamura, and J. Yamate
- Organizer
  The American College of Veterinary Pathologists (ACVP)
- Place of Presentation
  Atlanta, GA, USA.
- Year and Date
  2014-11-09 – 2014-11-11
- Data Source
  KAKENHI-PROJECT-26292152
[Presentation] Macrophage-derived galectin-3 is the key regulator of acute hepatic fibrogenesis in rats.
- Author(s)
  H. M. Golbar, T. Izawa, B. Alexandra, K. K. Wijesundera, A. H. Tennakoon, C. Katou-Ichikawa, M. Tanaka, M. Kuwamura and J. Yamate
- Organizer
  The 33rd Annual Symposium of the Society of Toxicologic Pathology (STP)
- Place of Presentation
  Washingon DC, USA.
- Year and Date
  2014-06-22 – 2014-06-26
- Data Source
  KAKENHI-PROJECT-26292152
[Presentation] Analyses of hepatic macrophages deplated by clodronate in rat liver
- Author(s)
  Pervin M, Golbar HM, Alexandra B, Wijesundera KK, Izawa T, Kuwamura M, Yamate J
- Organizer
  ACVP 2014 Annual Meeting
- Place of Presentation
  Atlanta, USA
- Year and Date
  2014-11-08 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-26850184
[Presentation] 非アルコール性脂肪性肝炎モデルラットにおける鉄過剰の病理学的役割の検討
- Author(s)
  井澤武史，新　真智，宮城伶奈，桑村　充，山手丈至
- Organizer
  第31回日本毒性病理学会学術集会
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Year and Date
  2015-01-29 – 2015-01-30
- Data Source
  KAKENHI-PROJECT-26850184

1. KUWAMURA Mitsuru (20244668)

# of Collaborated Projects: 9 results

# of Collaborated Products: 128 results
2. YAMATE Jyoji (50150115)

# of Collaborated Projects: 5 results

# of Collaborated Products: 108 results
3. TAKANAKA Shigeo (10280067)

# of Collaborated Projects: 5 results

# of Collaborated Products: 6 results
4. AKIYOSHI Shigeyasu (50420740)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. Harada Naoki (00529141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 白木伸明 (70448520)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 中村純 (90804518)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 岡田利也 (00169111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 片平じゅん (30263312)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 川西優喜 (70332963)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 中島崇行 (30333644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 佐々木光穂 (20432536)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 田中美有 (00756893)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. Kuramoto Takashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
15. 佐藤隆史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Izawa Takeshi 井澤 武史

IZAWA Takeshi 井澤 武史

Research Projects

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Co-Researchers

Elucidation of mechanism underlying toxicity resistance by human hepatocytes based on cell adhesion abnormalityPrincipal Investigator

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Elucidation of novel mechanism for hepatoprotection by iron overloadPrincipal Investigator

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Elucidation of the mechanism for disease modulation by iron overload in chronic liver diseasesPrincipal Investigator

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Molecular mechanisms of drug-induced liver injury based on metabolic liver diseasePrincipal Investigator

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Elucidation of inflammatory mechanism and pathologic role in iron dysregulation in chronic liver diseases.Principal Investigator

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Molecular pathology of iron dysregulation during progression of liver cirrhosisPrincipal Investigator

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Izawa Takeshi 井澤武史

IZAWA Takeshi 井澤武史