Fujikane Ryosuke 藤兼亮輔

… Alternative Names

藤兼亮輔フジカネリョウスケ

FUJIKANE Ryosuke 藤兼亮輔

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Researcher Number	20581713
Other IDs
Affiliation (Current)	2025: 福岡歯科大学, 口腔歯学部, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 福岡歯科大学, 口腔歯学部, 講師 2016: 福岡歯科大学, 口腔歯学部, 講師 2014 – 2015: 福岡歯科大学, 歯学部, 講師 2011 – 2013: 福岡歯科大学, 歯学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 57020:Oral pathobiological science-related / Tumor biology / Tumor biology Except Principal Investigator Basic Section 57020:Oral pathobiological science-related
Keywords	Principal Investigator ミスマッチ修復 / アルキル化剤 / アポトーシス / 合成致死 / DNA修復 / DNA損傷応答 / DNA複製ストレス / 細胞死 / 遺伝子トラップ法 Except Principal Investigator ゲノム安定化 … More / ストレス超感受性 / 細胞死 / 多能性幹細胞 / 細胞周期チェックポイント / 化学療法剤 / ATR/CHK1 / アポトーシス / 胞周期チェックポイント / DNA損傷応答 Less

合成致死性を用いた新しいがん治療法の検討~変異に応じた個別療法の確立を目指して~Principal Investigator
- Principal Investigator
  
  藤兼亮輔
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Fukuoka Dental College
化学療法剤超感受性を付与する高度なゲノム恒常性維持機構の解明
- Principal Investigator
  
  日高真純
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Fukuoka Dental College
Elucidation of tumor suppression mechanism through identification of novel proteins involved in mismatch repair-dependent apoptosisPrincipal Investigator
- Principal Investigator
  
  Fujikane Ryosuke
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Fukuoka Dental College
Elucidation of the molecular mechanism of the apoptosis pathway triggered by alkylated base lesionsPrincipal Investigator
- Principal Investigator
  
  FUJIKANE Ryosuke
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Fukuoka Dental College

All 2023 2022 2021 2020 2016 2015 2012 2011

All Journal Article Presentation

[Journal Article] Novel plasmids for the fluorescence-based evaluation of DNA mismatch repair in human cells2022
- Author(s)
  Takedachi Arato、Matsuishi Erina、Mizusaki Shouji、Nagasawa Tomoki、Fujikane Ryosuke、Hidaka Masumi、Iwai Shigenori、Kuraoka Isao
- Journal Title
  
  Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
  
  Volume: 824 Pages: 111779-111779
- DOI
  10.1016/j.mrfmmm.2022.111779
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09915, KAKENHI-PROJECT-19H04273, KAKENHI-PROJECT-20H03184
[Journal Article] Suppression of TopBP1 function increases the efficacy of chemotherapeutic treatments by enhancing the induction of apoptosis2021
- Author(s)
  Obayashi Yuko、Fujikane Ryosuke、Morita Shou、Uechi Yuka、Hiraki Akimitsu、Hidaka Masumi
- Journal Title
  
  Oral Science International
  
  Volume: 00 Issue: 3 Pages: 1-8
- DOI
  10.1002/osi2.1102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09915
[Journal Article] DNA polymerase delta Exo domain stabilizes mononucleotide microsatellites in human cells.2021
- Author(s)
  Shioi S, Shimamoto A, Song Y, Hidaka K, Nakamura M, Take A, Hayashi N, Takiguchi S, Fujikane R, Hidaka M, Oda S*, Nakatsu Y*
- Journal Title
  
  DNA Repair
  
  Volume: 108 Pages: 103216-103216
- DOI
  10.1016/j.dnarep.2021.103216
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07711, KAKENHI-PROJECT-20K09915
[Journal Article] Function of high-mobility groupA proteins in the DNA damage signaling for the induction of apoptosis2016
- Author(s)
  Fujikane, R., Komori, K., Sekiguchi, M., Hidaka, M.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 31714-31714
- DOI
  10.1038/srep31714
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25241012, KAKENHI-PROJECT-26340040, KAKENHI-PROJECT-26830085
[Journal Article] The identification of a novel gene, MAPO2, that is involved in the induction of apoptosis triggered by O6-methylguanine2012
- Author(s)
  Fujikane R., Sanada M., Sekiguchi M., Hidaka M.
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 9 Pages: e44817-e44817
- DOI
  10.1371/journal.pone.0044817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701065
[Presentation] 蛍光プラスミドを用いたミスマッチ修復効率の定量的解析2023
- Author(s)
  藤兼亮輔
- Organizer
  日本環境変異原ゲノム学会第52回大会
- Data Source
  KAKENHI-PROJECT-22K09956
[Presentation] Mechanism of mismatch repair-dependent apoptosis and its regulation by DNA damage response and DNA repair systems2023
- Author(s)
  Ryosuke FUJIKANE
- Organizer
  第96回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K09956
[Presentation] セントロメアタンパク質CENP-Aのアポトーシス誘導における新規機能2023
- Author(s)
  井口晃太郎、藤兼亮輔、日髙真純
- Organizer
  第50回福岡歯科大学学会総会
- Data Source
  KAKENHI-PROJECT-20K09915
[Presentation] 生細胞のDNAミスマッチ修復能を評価する新規レポータープラスミドの構築と評価2023
- Author(s)
  白川知樹、竹立新人、松石英莉那、水崎彰治、長澤知樹、藤兼亮輔、日高真純、石井成憲、倉岡功
- Organizer
  第52回日本環境変異原ゲノム学会
- Data Source
  KAKENHI-PROJECT-20K09915
[Presentation] アルキル化DNA損傷応答におけるセントロメアタンパク質CENP-Aの役割2023
- Author(s)
  井口晃太郎、藤兼亮輔、日髙真純
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-20K09915
[Presentation] 蛍光プラスミドを用いたミスマッチ修復効率の定量的解析2023
- Author(s)
  藤兼亮輔、倉岡功、日高真純
- Organizer
  第52回日本環境変異原ゲノム学会
- Data Source
  KAKENHI-PROJECT-20K09915
[Presentation] Mechanism of mismatch repair-dependent apoptosis and its regulation by DNA damage response and DNA repair systems2023
- Author(s)
  Fujikane R., Morita S., Rikitake M., Uechi Y., Hidaka M.
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K09915
[Presentation] アルキル化損傷応答におけるFANCD2の役割2023
- Author(s)
  森田祥、藤兼亮輔、上地有香、松浦尚志、日髙真純
- Organizer
  第27回DNA複製・組換え・修復ワークショップ
- Data Source
  KAKENHI-PROJECT-20K09915
[Presentation] アルキル化損傷応答におけるミスマッチ修復因子PMS1の機能.2022
- Author(s)
  藤兼亮輔, 上地有香, 森田祥, 得居果乃, 日高真純
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K09956
[Presentation] 生細胞のミスマッチ修復能をリアルタイムで評価できるプラスミドの構築と評価2022
- Author(s)
  竹立新人、白川知樹、松石英莉那、水崎彰治、長澤知樹、藤兼亮輔、日髙真純、岩井成憲、倉岡功
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K09915
[Presentation] ミスマッチ修復MutL複合体遺伝子欠損細胞におけるHPRT遺伝子変異の解析2022
- Author(s)
  得居果乃、藤兼亮輔、日髙真純
- Organizer
  第49回福岡歯科大学学会総会
- Data Source
  KAKENHI-PROJECT-20K09915
[Presentation] アルキル化損傷応答におけるミスマッチ修復因子PMS1の機能2022
- Author(s)
  藤兼亮輔、上地有香、森田祥、得居果乃、日髙真純
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K09915
[Presentation] アポトーシス誘導におけるミBLM-スマッチ修復タンパク質複合体の機能解析2022
- Author(s)
  上地有香、藤兼亮輔、森田祥、玉置幸雄、日髙真純
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K09915
[Presentation] アルキル化損傷応答におけるFANCD2の役割2022
- Author(s)
  森田祥, 藤兼亮輔, 上地有香, 松浦尚志, 日高真純
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K09956
[Presentation] アルキル化損傷応答におけるミスマッチ修復因子FANCD2の役割2022
- Author(s)
  森田祥、藤兼亮輔、上地有香、松浦尚志、日髙真純
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K09915
[Presentation] アルキル化DNA損傷応答におけるミスマッチ修復因子PMS1の機能の解析2021
- Author(s)
  藤兼亮輔、森田祥、上地有香、日髙真純
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K09915
[Presentation] アポトーシス誘導におけるBLMとミスマッチ修復タンパク質との相互作用の機能解析2021
- Author(s)
  上地有香、藤兼亮輔、森田祥、玉置幸雄、日髙真純
- Organizer
  第48回福岡歯科大学学会総会
- Data Source
  KAKENHI-PROJECT-20K09915
[Presentation] DNAポリメラーゼδExoドメイン変異によって不安定化される一塩基繰り返しマイクロサテライ2021
- Author(s)
  織田信弥、塩井誠次郎、瀧口聡一、日高京子、藤兼亮輔、日高真純、中津可道
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K09915
[Presentation] WRNノックアウト、ノックダウンがHeLa MR細胞の薬剤感受性へ及ぼす影響2021
- Author(s)
  森田祥、藤兼亮輔、上地有香、松浦尚志、日髙真純
- Organizer
  第48回福岡歯科大学学会総会
- Data Source
  KAKENHI-PROJECT-20K09915
[Presentation] Suppression of TopBP1 expression impairs the DNA damage response and promotes the induction of apoptosis by chemotherapeutic agents2020
- Author(s)
  Obayashi Y., Fujikane R., Uechi Y., Morita S., Ikebe T., Hiraki A., Hidaka M.
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20K09915
[Presentation] アルキル化剤によって引き起こされるアポトーシスに関わる新規因子の同定と解析2016
- Author(s)
  藤兼亮輔, 関口睦夫, 日高真純
- Organizer
  第23回日本歯科医学会総会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2016-10-21
- Data Source
  KAKENHI-PROJECT-26830085
[Presentation] ミスマッチ修復タンパク質依存のアポトーシス誘導におけるHMGAファミリータンパク質の機能2016
- Author(s)
  藤兼亮輔、武石幸容、関口睦夫、日髙真純
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26830085
[Presentation] O6メチルグアニンによりひき起こされるミスマッチ修復依存のアポトーシス誘導に関わる新規因子の同定2015
- Author(s)
  藤兼亮輔、関口睦夫、日高真純
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26830085
[Presentation] The identification of a novel gene, MAPO2, that is involved in the induction of apoptosis triggered by O6-methylguanine2012
- Author(s)
  Fujikane R, Sanada, M, Sekiguchi M, and Hidaka M
- Organizer
  The 8th International Symposium on DNA Replication, Recombination, and Repair
- Place of Presentation
  淡路夢舞台国際会議場
- Data Source
  KAKENHI-PROJECT-23701065
[Presentation] The identification of a novel gene, MAPO2, that is involved in the induction of apoptosis triggered by O6-methylguanine2012
- Author(s)
  Fujikane R., Sanada M., Sekiguchi M., Hidaka M.
- Organizer
  The 8th International Symposium on DNA Replication, Recombination, and Repair
- Place of Presentation
  兵庫県淡路市
- Data Source
  KAKENHI-PROJECT-23701065
[Presentation] A novel gene, C10, is related to the induction of apoptosis triggered by O6-methylguanine2011
- Author(s)
  Fujikane R, Sanada, M, Sekiguchi M, and Hidaka M
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-23701065
[Presentation] 新規遺伝子C10の同定と解析2011
- Author(s)
  R Fujikane, M Sanada, M Sekiguchi and M Hidaka
- Organizer
  第３４回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23701065

1. 日高真純 (80238310)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
2. 瀧口総一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 織田信弥

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fujikane Ryosuke 藤兼 亮輔

藤兼 亮輔 フジカネ リョウスケ

FUJIKANE Ryosuke 藤兼 亮輔

Research Projects

Research Products

Co-Researchers

合成致死性を用いた新しいがん治療法の検討~変異に応じた個別療法の確立を目指して~Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

化学療法剤超感受性を付与する高度なゲノム恒常性維持機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of tumor suppression mechanism through identification of novel proteins involved in mismatch repair-dependent apoptosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the molecular mechanism of the apoptosis pathway triggered by alkylated base lesionsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Novel plasmids for the fluorescence-based evaluation of DNA mismatch repair in human cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Suppression of TopBP1 function increases the efficacy of chemotherapeutic treatments by enhancing the induction of apoptosis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DNA polymerase delta Exo domain stabilizes mononucleotide microsatellites in human cells.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Function of high-mobility groupA proteins in the DNA damage signaling for the induction of apoptosis2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The identification of a novel gene, MAPO2, that is involved in the induction of apoptosis triggered by O6-methylguanine2012

Author(s)

Journal Title

DOI

Data Source

[Presentation] 蛍光プラスミドを用いたミスマッチ修復効率の定量的解析2023

Author(s)

Organizer

Data Source

[Presentation] Mechanism of mismatch repair-dependent apoptosis and its regulation by DNA damage response and DNA repair systems2023

Author(s)

Organizer

Data Source

[Presentation] セントロメアタンパク質CENP-Aのアポトーシス誘導における新規機能2023

Author(s)

Organizer

Data Source

[Presentation] 生細胞のDNAミスマッチ修復能を評価する新規レポータープラスミドの構築と評価2023

Author(s)

Organizer

Data Source

[Presentation] アルキル化DNA損傷応答におけるセントロメアタンパク質CENP-Aの役割2023

Author(s)

Organizer

Data Source

[Presentation] 蛍光プラスミドを用いたミスマッチ修復効率の定量的解析2023

Author(s)

Organizer

Data Source

[Presentation] Mechanism of mismatch repair-dependent apoptosis and its regulation by DNA damage response and DNA repair systems2023

Fujikane Ryosuke 藤兼亮輔

藤兼亮輔フジカネリョウスケ

FUJIKANE Ryosuke 藤兼亮輔