Kudo Toshihiro 工藤敏啓

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KUDO Toshihiro 工藤敏啓

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Researcher Number	20593859
Affiliation (Current)	2025: 地方独立行政法人大阪府立病院機構大阪国際がんセンター(研究所), その他部局等, 腫瘍内科部長
Affiliation (based on the past Project Information) *help	2018 – 2020: 地方独立行政法人大阪府立病院機構大阪国際がんセンター(研究所), その他部局等, 腫瘍内科副部長 2016 – 2017: 大阪大学, 医学系研究科, 寄附講座助教 2013 – 2015: 大阪大学, 医学(系)研究科(研究院), 寄附講座助教
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related / General surgery / Digestive surgery Except Principal Investigator General surgery
Keywords	Principal Investigator 癌 / バイオマーカー / 創薬 / ピルビン酸キナーゼ / 代謝 / 転移 / がん / シングル細胞 / 化学療法 / 臨床 / 核酸 / 薬学 / 発現制御 … More Except Principal Investigator … More 酵素 / 癌 Less

Elucidation and application of early brain metastasis mechanism by Warburg regulator MPCPrincipal Investigator
- Principal Investigator
  
  KUDO Toshihiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka International Cancer Institute
New development of epigenome drug discovery to realize oncogene selectivity
- Principal Investigator
  
  SATOH Taroh
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Osaka University
Elucidation of epigenetic modification mechanisms of long non-coding RNAsPrincipal Investigator
- Principal Investigator
  
  Kudo Toshihiro
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Osaka University
Find out of Nrf2 function and development of the inhibitor of Nrf2 for cancer stem cellsPrincipal Investigator
- Principal Investigator
  
  KUDO Toshihiro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University

All 2020 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Practical guidance for the evaluation of disease progression and the decision to change treatment in patients with advanced gastric cancer receiving chemotherapy2020
- Author(s)
  Iwasa Satoru、Kudo Toshihiro、Takahari Daisuke、Hara Hiroki、Kato Ken、Satoh Taroh
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 25 Issue: 7 Pages: 1223-1232
- DOI
  10.1007/s10147-020-01684-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08704
[Journal Article] Evaluation of FOLFOX or CAPOX reintroduction with or without bevacizumab in relapsed colorectal cancer patients treated with oxaliplatin as adjuvant chemotherapy (REACT study)2020
- Author(s)
  Kotaka Masahito、Iwamoto Shigeyoshi、Satake Hironaga、Sakai Daisuke、Kudo Toshihiro、Fukunaga Mutsumi、Konishi Ken、Ide Yoshihito、Ikumoto Taro、Tsuji Akihito、Sano Yasushi、Kato Takeshi、Sugimoto Naotoshi、Satoh Taroh、Kanazawa Akiyoshi、Kurata Takayasu、Yamanaka Takeharu、Tomita Naohiro
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 25 Issue: 8 Pages: 1515-1522
- DOI
  10.1007/s10147-020-01701-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08617, KAKENHI-PROJECT-18K08704
[Journal Article] Association of iron metabolic enzyme hepcidin expression levels with the prognosis of patients with pancreatic cancer2018
- Author(s)
  Toshiyama Reishi、Konno Masamitsu、Eguchi Hidetoshi、Asai Ayumu、Noda Takehiro、Koseki Jun、Asukai Kei、Ohashi Tomofumi、Matsushita Katsunori、Iwagami Yoshifumi、Yamada Daisaku、Asaoka Tadafumi、Wada Hiroshi、Kawamoto Koichi、Gotoh Kunihito、Kudo Toshihiro、Satoh Taroh、Doki Yuichiro、Mori Masaki、Ishii Hideshi
- Journal Title
  
  Oncology Letters
  
  Volume: 15 Pages: 8125-8133
- DOI
  10.3892/ol.2018.8357
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08704, KAKENHI-PROJECT-18K16355, KAKENHI-PROJECT-18K16356, KAKENHI-PROJECT-18KK0251, KAKENHI-PROJECT-17H04282, KAKENHI-PROJECT-17K19698
[Journal Article] Enzymes of the one-carbon folate metabolism as anticancer targets predicted by survival rate analysis2018
- Author(s)
  Koseki Jun、Konno Masamitsu、Asai Ayumu、Colvin Hugh、Kawamoto Koichi、Nishida Naohiro、Sakai Daisuke、Kudo Toshihiro、Satoh Taroh、Doki Yuichiro、Mori Masaki、Ishii Hideshi
- Journal Title
  
  Sci. Rep.
  
  Volume: 8 Issue: 1 Pages: 303-303
- DOI
  10.1038/s41598-017-18456-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19698, KAKENHI-PROJECT-17H04282, KAKENHI-PROJECT-15H05664, KAKENHI-PROJECT-16K15591, KAKENHI-PROJECT-16K15592, KAKENHI-PROJECT-16K15615, KAKENHI-PROJECT-16K15616
[Journal Article] Cell?free culture conditioned medium elicits pancreatic β cell lineage?specific epigenetic reprogramming in mice2018
- Author(s)
  Kawamoto Koichi、Ohashi Tomofumi、Konno Masamitsu、Nishida Naohiro、Koseki Jun、Matsui Hidetoshi、Sakai Daisuke、Kudo Toshihiro、Eguchi Hidetoshi、Satoh Taroh、Doki Yuichiro、Mori Masaki、Ishii Hideshi
- Journal Title
  
  Oncology Letters
  
  Volume: 16 Pages: 3255-3259
- DOI
  10.3892/ol.2018.9008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08617, KAKENHI-PROJECT-18K08704, KAKENHI-PROJECT-18K16356, KAKENHI-PROJECT-18KK0251, KAKENHI-PROJECT-16H02790, KAKENHI-PROJECT-17H04282, KAKENHI-PROJECT-17K19698
[Journal Article] Computational trans-omics approach characterised methylomic and transcriptomic involvements and identified novel therapeutic targets for chemoresistance in gastrointestinal cancer stem cells2018
- Author(s)
  Konno Masamitsu、Matsui Hidetoshi、Koseki Jun、Asai Ayumu、Kano Yoshihiro、Kawamoto Koichi、Nishida Naohiro、Sakai Daisuke、Kudo Toshihiro、Satoh Taroh、Doki Yuichiro、Mori Masaki、Ishii Hideshi
- Journal Title
  
  Sci. Rep.
  
  Volume: 8 Issue: 1 Pages: 899-899
- DOI
  10.1038/s41598-018-19284-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19698, KAKENHI-PROJECT-15H01678, KAKENHI-PROJECT-17H04282, KAKENHI-PROJECT-15H05664, KAKENHI-PROJECT-16K15591, KAKENHI-PROJECT-16K15592, KAKENHI-PROJECT-16K15615, KAKENHI-PROJECT-16K15616
[Journal Article] Hypoxia stimulates the cytoplasmic localization of oncogenic long noncoding RNA LINC00152 in colorectal cancer2017
- Author(s)
  Nishizawa Yujiro、Konno Masamitsu、Asai Ayumu、Koseki Jun、Kawamoto Koichi、Miyoshi Norikatsu、Takahashi Hidekazu、Nishida Naohiro、Haraguchi Naotsugu、Sakai Daisuke、Kudo Toshihiro、Hata Taishi、Matsuda Chu、Mizushima Tsunekazu、Satoh Taroh、Doki Yuichiro、Mori Masaki、Ishii Hideshi
- Journal Title
  
  Int. J. Oncol.
  
  Volume: 52 Pages: 453-460
- DOI
  10.3892/ijo.2017.4218
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19698, KAKENHI-PROJECT-17H04282, KAKENHI-PROJECT-15H05664, KAKENHI-PROJECT-16K15591, KAKENHI-PROJECT-16K15592, KAKENHI-PROJECT-16K15615, KAKENHI-PROJECT-16K15616
[Journal Article] Oncogene c-Myc promotes epitranscriptome m6A reader YTHDF1 expression in colorectal cancer2017
- Author(s)
  Nishizawa Yujiro、Konno Masamitsu、Asai Ayumu、Koseki Jun、Kawamoto Koichi、Miyoshi Norikatsu、Takahashi Hidekazu、Nishida Naohiro、Haraguchi Naotsugu、Sakai Daisuke、Kudo Toshihiro、Hata Taishi、Matsuda Chu、Mizushima Tsunekazu、Satoh Taroh、Doki Yuichiro、Mori Masaki、Ishii Hideshi
- Journal Title
  
  Oncotarget.
  
  Volume: 9 Issue: 7 Pages: 7476-7486
- DOI
  10.18632/oncotarget.23554
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19698, KAKENHI-PROJECT-17H04282, KAKENHI-PROJECT-15H05664, KAKENHI-PROJECT-16K15591, KAKENHI-PROJECT-16K15592, KAKENHI-PROJECT-16K15615, KAKENHI-PROJECT-16K15616
[Journal Article] Impact of capecitabine and S-1 on anticoagulant activity of warfarin in patients with gastrointestinal cancer.2016
- Author(s)
  Hata, T., Kudo, T., Sakai, D., Takahashi, H., Haraguchi, N., Nishimura, J., Hata, T., Mizushima, T., Yamamoto, H., Doki, Y., Mori, M., Satoh, T.
- Journal Title
  
  Cancer Chemother Pharmacol.
  
  Volume: 78 Issue: 2 Pages: 389-396
- DOI
  10.1007/s00280-016-3080-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15475, KAKENHI-PROJECT-16K15592
[Journal Article] Efficacy and Safety of Regorafenib or TAS-102 in Patients with Metastatic Colorectal Cancer Refractory to Standard Therapies.2016
- Author(s)
  Sueda, T., Sakai, D., Kudo, T., Sugiura, T., Takahashi, H., Haraguchi, N., Nishimura, J., Hata, T., Hayashi, T., Mizushima, T., Doki, Y., Mori, M., Satoh, T.
- Journal Title
  
  Anticancer Res.
  
  Volume: 36 Pages: 4299-4306
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15475
[Journal Article] Multi-center Clinical Study Group of Osaka, Colorectal Cancer Treatment Group (MCSGO). Combination antiemetic therapy with aprepitant/fosaprepitant in patients with colorectal cancer receiving oxaliplatin-based chemotherapy (SENRI trial): a multicentre, randomised, controlled phase 3 trial.2015
- Author(s)
  Nishimura J, Satoh T, Fukunaga M, Takemoto H, Nakata K, Ide Y, Fukuzaki T, Kudo T, Miyake Y, Yasui M, Morita S, Sakai D, Uemura M, et al.
- Journal Title
  
  Eur J Cancer
  
  Volume: 51(10) Issue: 10 Pages: 1274-82
- DOI
  10.1016/j.ejca.2015.03.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10140, KAKENHI-PROJECT-15K15475
[Journal Article] Safety and pharmacokinetics of S-1 in a recurrent colon cancer patient with chronic myeloid leukemia treated with dasatinib: A case report.2014
- Author(s)
  Sueda T., Kudo T., Sakai D., Uemura M., Nishimura J., Hata T., Takemasa I., Mizushima T., Yamamoto H., Ezoe S., Matsumoto K., Doki Y., Mori M., Satoh T.
- Journal Title
  
  Cancer Chemother Pharmacol.
  
  Volume: 74 Issue: 6 Pages: 1321-1324
- DOI
  10.1007/s00280-014-2620-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670576, KAKENHI-PROJECT-25670577, KAKENHI-PROJECT-26670603
[Journal Article] Aldehyde dehydrogenase high gastric cancer stem cells are resistant to chemotherapy.2013
- Author(s)
  Nishikawa, S., Konno, M., Hamabe, A., Hasegawa, S., Kano, Y., Ohta, K., Fukusumi, T., Sakai, D., Kudo, T., Haraguchi, N., Satoh, T., Takiguchi, S., Mori, M., Doki,Y., Ishii, H.
- Journal Title
  
  Int. J. Oncol.
  
  Volume: 42 Issue: 4 Pages: 1437-1442
- DOI
  10.3892/ijo.2013.1837
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390199, KAKENHI-PROJECT-24790730, KAKENHI-PUBLICLY-25112708, KAKENHI-PROJECT-25670556, KAKENHI-PROJECT-25670576
[Journal Article] Eradication of therapy-resistant cancer cells in gastrointestinal organs.2013
- Author(s)
  Nishikawa, S., Konno, M., Hamabe, A., Hasegawa, S., Ogawa, H., Kano, Y., Fukusumi, T., Ohta, K., Noguchi, Y., Ozaki, M., Kudo, T., Sakai, D., Haraguchi, N., Satoh, T., Doki, Y., Mori, M., Ishii, H.
- Journal Title
  
  Mol. Clin. Oncol.
  
  Volume: 1 Pages: 15-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670576
[Journal Article] Jumonji/Arid1b (Jarid1b) protein modulates human esophageal cancer cell growth.2013
- Author(s)
  Kano, Y., Konno, M., Ohta, K., Haraguchi, N., Nishikawa, S., Kagawa, Y., Hamabe, A., Hasegawa, S., Ogawa, H., Fukusumi, T., Noguchi, Y., Ozaki, M., Kudo, T., Sakai, D., Satoh, T., Ishii, M., Mizohata, E., Inoue, T., Mori, M., Doki, Y., Ishii, H.
- Journal Title
  
  Mol. Clin. Oncol.
  
  Volume: 1 Pages: 753-757
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670576
[Journal Article] Depletion of Jarid1b induces cellular senescence in human colorectal cancer.2013
- Author(s)
  Ohta, K., Haraguchi, N., Kano, Y., Kagawa, Y., Konno, M., Nishikawa, S., Hamabe, A., Hasegawa, S., Ogawa, H., Fukusumi, T., Uemura, M., Nishimura, J., Hata, T., Takemasa, I., Nishimura, T., Noguchi, Y., Ozaki, M., Kudo, T., Sakai, D., Satoh, T., Fukami, M., Ishii, M., Yamamoto, H., Doki, Y., Mori, M., Ishii, H.
- Journal Title
  
  Intern. J. Oncol.
  
  Volume: 42 Issue: 4 Pages: 1212-1218
- DOI
  10.3892/ijo.2013.1799
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390199, KAKENHI-PROJECT-23659617, KAKENHI-PROJECT-24790730, KAKENHI-PUBLICLY-25112708, KAKENHI-PROJECT-25670556, KAKENHI-PROJECT-25670576, KAKENHI-PROJECT-25670577, KAKENHI-PUBLICLY-23112514
[Journal Article] Adipose-derived mesenchymal stem cells and regenerative medicine.2013
- Author(s)
  Konno, M., Hamabe, A., Hasegawa, S., Ogawa, H., Fukusumi, T., Nishikawa, S., Ohta, K., Kano, Y., Ozaki, M., Noguchi, Y., Sakai, D., Kudoh, T., Kawamoto, K., Eguchi, H., Satoh, T., Tanemura, M., Nagano, H., Doki, Y., Mori, M., Ishii, H.
- Journal Title
  
  Dev. Growth Differ.
  
  Volume: 55 Issue: 3 Pages: 309-318
- DOI
  10.1111/dgd.12049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390199, KAKENHI-PROJECT-24790730, KAKENHI-PUBLICLY-25134711, KAKENHI-PROJECT-25461946, KAKENHI-PROJECT-25670556, KAKENHI-PROJECT-25670576, KAKENHI-PROJECT-25670577
[Presentation] これからの胃がん薬物療法を考える2020
- Author(s)
  工藤敏啓
- Organizer
  第 99 回日本消化器内視鏡学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08704
[Presentation] mFOLFOX6 + ベバシズマブ療法により高アンモニア血症を来すも分岐鎖アミノ酸製剤により継続可能となった進行結腸がんの一例2013
- Author(s)
  工藤敏啓、佐藤太郎、坂井大介、杉浦孝司、竹政伊知朗、山本浩文、石井秀始、森正樹
- Organizer
  第１１回日本臨床腫瘍学会学術集会
- Place of Presentation
  仙台国際センター(宮城県）
- Data Source
  KAKENHI-PROJECT-25670576
[Presentation] Clinical validation of a novel multiplex kit for all RAS mutations in colorectal cancer: Results of RASKET(RAS Key Testing)prospective multicenter…
- Author(s)
  Kudo T., Hironaka S, Okamoto W, Yoshino T, Muro K, Taniguchi H, Akagi K, Nishina T, Kajiwara T, DendaT.
- Organizer
  ESMO 2014
- Place of Presentation
  IFEMA ‐ Feria de Madrid（スペイン）
- Year and Date
  2014-09-26 – 2014-09-30
- Data Source
  KAKENHI-PROJECT-25670576

1. ISHII Hideshi (10280736)

# of Collaborated Projects: 4 results

# of Collaborated Products: 12 results
2. KONNO Masamitsu (80618207)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
3. 小関準 (20616669)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
4. Mori Masaki (70190999)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
5. SATOH Taroh (40368303)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. 西田尚弘 (50588118)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 川本弘一 (30432470)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
8. 坂井大介 (10621071)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
9. DOKI yuichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
10. 植村守

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kudo Toshihiro 工藤 敏啓

KUDO Toshihiro 工藤 敏啓

Research Projects

Research Products

Co-Researchers

Elucidation and application of early brain metastasis mechanism by Warburg regulator MPCPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

New development of epigenome drug discovery to realize oncogene selectivity

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of epigenetic modification mechanisms of long non-coding RNAsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Find out of Nrf2 function and development of the inhibitor of Nrf2 for cancer stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Practical guidance for the evaluation of disease progression and the decision to change treatment in patients with advanced gastric cancer receiving chemotherapy2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of FOLFOX or CAPOX reintroduction with or without bevacizumab in relapsed colorectal cancer patients treated with oxaliplatin as adjuvant chemotherapy (REACT study)2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association of iron metabolic enzyme hepcidin expression levels with the prognosis of patients with pancreatic cancer2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Enzymes of the one-carbon folate metabolism as anticancer targets predicted by survival rate analysis2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cell?free culture conditioned medium elicits pancreatic β cell lineage?specific epigenetic reprogramming in mice2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Computational trans-omics approach characterised methylomic and transcriptomic involvements and identified novel therapeutic targets for chemoresistance in gastrointestinal cancer stem cells2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hypoxia stimulates the cytoplasmic localization of oncogenic long noncoding RNA LINC00152 in colorectal cancer2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oncogene c-Myc promotes epitranscriptome m6A reader YTHDF1 expression in colorectal cancer2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of capecitabine and S-1 on anticoagulant activity of warfarin in patients with gastrointestinal cancer.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Efficacy and Safety of Regorafenib or TAS-102 in Patients with Metastatic Colorectal Cancer Refractory to Standard Therapies.2016

Author(s)

Journal Title

Data Source

Author(s)

Journal Title

Kudo Toshihiro 工藤敏啓

KUDO Toshihiro 工藤敏啓