Ito Takashi 伊藤孝

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ITO Takashi 伊藤孝

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Researcher Number	20597124
Other IDs	https://orcid.org/0000-0002-2521-0237
Affiliation (Current)	2025: 東洋大学, 食環境科学部, 助教
Affiliation (based on the past Project Information) *help	2025: 国立研究開発法人理化学研究所, 環境資源科学研究センター, 上級研究員 2021 – 2023: 国立研究開発法人理化学研究所, 環境資源科学研究センター, 上級研究員 2020: 国立研究開発法人理化学研究所, 環境資源科学研究センター, 研究員 2013: 千葉大学, 医学部附属病院, 特任助教 2012: 千葉大学, 医学(系)研究科(研究院), 研究員
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / General medical chemistry
Keywords	Principal Investigator 寿命 / 腸内細菌 / mTOR / エネルギー代謝 / ミトコンドリア呼吸 / 寿命延長 / 神経障害 / 呼吸 / ミトコンドリア病 / 解糖系 … More / 乳酸 / 乳酸菌 / ミトコンドリア / 個体老化 / PAK2 / 老化 / 動脈硬化 / CDC42 / 血管内皮細胞 / 細胞老化 / 慢性炎症 Less

解糖系阻害によるミトコンドリア機能向上Principal Investigator
- Principal Investigator
  
  伊藤孝
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Institute of Physical and Chemical Research
Mechanisms of mitochondrial disease suppression and lifespan extension by lactic acid bacteriaPrincipal Investigator
- Principal Investigator
  
  Ito Takashi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Institute of Physical and Chemical Research
Role of CDC42 in pro-inflammatory phenotype of senescent vascular endothelial cellsPrincipal Investigator
- Principal Investigator
  
  ITO Takashi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Chiba University

All 2023 2022 2021 2020 2013 2012 Other

All Journal Article Presentation Patent

[Journal Article] Acarbose suppresses symptoms of mitochondrial disease in a mouse model of Leigh syndrome2023
- Author(s)
  Bitto A, Grillo AS, Ito TK, Stanaway IB, Nguyen BMG, Ying K, Tung H, Smith K, Tran N, Velikanje G, Urfer SR, Snyder JM, Barton J, Sharma A, Kayser EB, Wang L, Smith DL Jr, Thompson JW, DuBois L, DePaolo W, Kaeberlein M.
- Journal Title
  
  Nature Metabolism
  
  Volume: 5 Issue: 6 Pages: 955-967
- DOI
  10.1038/s42255-023-00815-w
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11553
[Journal Article] PKC downregulation upon rapamycin treatment attenuates mitochondrial disease2020
- Author(s)
  Martin-Perez Miguel、Grillo Anthony S.、Ito Takashi K.、Valente Anthony S.、Han Jeehae、Entwisle Samuel W.、Huang Heather Z.、Kim Dayae、Yajima Masanao、Kaeberlein Matt、Vill?n Judit
- Journal Title
  
  Nature Metabolism
  
  Volume: 2 Issue: 12 Pages: 1472-1481
- DOI
  10.1038/s42255-020-00319-x
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11553
[Patent] ミトコンドリア機能改善剤2020
- Inventor(s)
  伊藤孝、他
- Industrial Property Rights Holder
  伊藤孝、他
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Overseas
- Data Source
  KAKENHI-PROJECT-20K11553
[Patent] ミトコンドリア機能改善剤2020
- Inventor(s)
  Takashi Ito
- Industrial Property Rights Holder
  浜松医科大学、明治
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Acquisition Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-20K11553
[Patent] ミトコンドリア機能改善剤2020
- Inventor(s)
  伊藤孝　他4名
- Industrial Property Rights Holder
  伊藤孝　他4名
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Overseas
- Data Source
  KAKENHI-PROJECT-20K11553
[Presentation] 乳酸がミトコンドリア病様症状を改善する作用機序の解析2023
- Author(s)
  伊藤　孝
- Organizer
  第22回日本ミトコンドリア学会年会
- Data Source
  KAKENHI-PROJECT-20K11553
[Presentation] 解糖系酵素PFK1新規阻害剤TLAMのSAMP8マウスにおける効果2023
- Author(s)
  伊藤　孝
- Organizer
  第38回老化促進モデルマウス（SAM）学会学術大会
- Data Source
  KAKENHI-PROJECT-20K11553
[Presentation] Lactate inhibits glycolysis and attenuates mitochondrial disease2023
- Author(s)
  伊藤　孝
- Organizer
  Cell Symposia: Multifaceted Mitochondria (Spain)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11553
[Presentation] 長寿の生物学と社会実装への挑戦2023
- Author(s)
  伊藤　孝
- Organizer
  第52回繊維学会夏季セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-20K11553
[Presentation] Lactate inhibits glycolysis and attenuates mitochondrial disease2022
- Author(s)
  Takashi Ito, Haruna Nishimura, Sari Nurmila, Hiroki Kobayashi, Minoru Yoshida
- Organizer
  Cell Symposia: Multifaceted Mitochondri
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11553
[Presentation] 乳酸投与はミトコンドリア病モデルNdufs4 KOマウスの寿命を延長する2021
- Author(s)
  Takashi Ito
- Organizer
  日本ミトコンドリア学会
- Data Source
  KAKENHI-PROJECT-20K11553
[Presentation] mTOR経路阻害でリー脳症モデルNdufs4 KOマウス寿命を延長する分子機構2021
- Author(s)
  伊藤　孝、小林　大貴、吉田　稔
- Organizer
  J-mit 特別オンラインシンポジウム
- Data Source
  KAKENHI-PROJECT-20K11553
[Presentation] mTOR経路阻害でリー脳症モデルNdufs4 KOマウス寿命を延長する分子機構2021
- Author(s)
  Takashi Ito
- Organizer
  日本基礎老化学会
- Data Source
  KAKENHI-PROJECT-20K11553
[Presentation] How does inhibition of mTOR promote longevity in mammals?2020
- Author(s)
  Takashi Ito
- Organizer
  8th Symposium of the Smart-Aging Research Center
- Invited
- Data Source
  KAKENHI-PROJECT-20K11553
[Presentation] mTOR経路と腸内細菌がマウス寿命に及ぼす影響2020
- Author(s)
  伊藤　孝
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K11553
[Presentation] CDC42経路が老化血管内皮細胞の炎症誘導を制御する2013
- Author(s)
  伊藤孝, 南野徹
- Organizer
  第13回日本抗加齢医学総会
- Invited
- Data Source
  KAKENHI-PROJECT-24790272
[Presentation] CDC42 and NFκB signaling contribute to pro-inflammatory phenotype of senescent endothelial cells2012
- Author(s)
  Ito T, Minamino T
- Organizer
  41st Annual Meeting of The American Aging Association
- Place of Presentation
  (口頭発表)
- Data Source
  KAKENHI-PROJECT-24790272
[Presentation] CDC42 and NFκB signaling contribute to pro-inflammatory phenotype of senescent endothelial cells.2012
- Author(s)
  伊藤　孝
- Organizer
  Keystone Symposium on Aging and Diseases of Aging (S2)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790272
[Presentation] 老化血管内皮細胞による炎症誘導にCDC42経路とNFκB経路が寄与する2012
- Author(s)
  伊藤孝, 南野徹
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  (ポスター発表かつ口頭発表)
- Data Source
  KAKENHI-PROJECT-24790272
[Presentation] CDC42 and NFκB signaling contribute to pro-inflammatory phenotype of senescent endothelial cells2012
- Author(s)
  Ito T, Minamino T
- Organizer
  Keystone Symposium Aging and Diseases of Aging(S2)
- Place of Presentation
  (ポスター発表かつ口頭発表, Travel award受賞)
- Data Source
  KAKENHI-PROJECT-24790272
[Presentation] CDC42経路が老化血管内皮細胞の炎症誘導を制御する
- Author(s)
  伊藤　孝
- Organizer
  第13回日本抗加齢医学総会
- Place of Presentation
  横浜パシフィコ
- Invited
- Data Source
  KAKENHI-PROJECT-24790272

1. MINAMINO Tohru (90328063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results

Ito Takashi 伊藤 孝

ITO Takashi 伊藤 孝

Research Projects

Research Products

Co-Researchers

解糖系阻害によるミトコンドリア機能向上Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms of mitochondrial disease suppression and lifespan extension by lactic acid bacteriaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of CDC42 in pro-inflammatory phenotype of senescent vascular endothelial cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Acarbose suppresses symptoms of mitochondrial disease in a mouse model of Leigh syndrome2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PKC downregulation upon rapamycin treatment attenuates mitochondrial disease2020

Author(s)

Journal Title

DOI

Data Source

[Patent] ミトコンドリア機能改善剤2020

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Patent] ミトコンドリア機能改善剤2020

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Acquisition Date

Data Source

[Patent] ミトコンドリア機能改善剤2020

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] 乳酸がミトコンドリア病様症状を改善する作用機序の解析2023

Author(s)

Organizer

Data Source

[Presentation] 解糖系酵素PFK1新規阻害剤TLAMのSAMP8マウスにおける効果2023

Author(s)

Organizer

Data Source

[Presentation] Lactate inhibits glycolysis and attenuates mitochondrial disease2023

Author(s)

Organizer

Data Source

[Presentation] 長寿の生物学と社会実装への挑戦2023

Author(s)

Organizer

Data Source

[Presentation] Lactate inhibits glycolysis and attenuates mitochondrial disease2022

Author(s)

Organizer

Data Source

[Presentation] 乳酸投与はミトコンドリア病モデルNdufs4 KOマウスの寿命を延長する2021

Author(s)

Organizer

Data Source

[Presentation] mTOR経路阻害でリー脳症モデルNdufs4 KOマウス寿命を延長する分子機構2021

Author(s)

Organizer

Data Source

Ito Takashi 伊藤孝

ITO Takashi 伊藤孝