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Misawa Aya  三沢 彩

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… Alternative Names

三沢 彩  ミサフ アヤ

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Researcher Number 20598453
Other IDs
Affiliation (based on the past Project Information) *help 2024: 国際医療福祉大学, 医学部, 講師
2021 – 2023: 国際医療福祉大学, 基礎医学研究センター, 講師
2022: 国際医療福祉大学, 医学部, 講師
2020: 慶應義塾大学, 医学部(信濃町), 特任講師
2018 – 2019: 日本医科大学, 医学部, 講師 … More
2017: 日本医科大学, 医学部, 助教
2016: 日本医科大学, 大学院医学研究科, 助教
2011: 東京大学, 医学部附属病院, 特任研究員 Less
Review Section/Research Field
Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 56030:Urology-related / Tumor biology / Tumor biology
Except Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords
Principal Investigator
前立腺癌 / 前立腺がん / 骨転移 / ncRNA / lncRNA / Osteomimicry / 癌微小環境 / 細胞外小胞体 / エネルギー代謝 / 免疫チェックポイント阻害薬 … More / T 細胞 / 代謝 / インテグリン / サイトカイン / TNAP / AR / miRNA / TNSAP / HOTAIR / ALPL / 石灰化 / エピジェネティクス / 転移 / 次世代シーケンサー / アンドロゲン / AR受容体 / microRNA … More
Except Principal Investigator
Checkpoint inhibitors / tumor microenvironment / Immunotherapy / Statins / Immuno-metabolism / anti-tumor responses / inhibitory molecules / T cell immune function / statins / lipid lowering agents / 免疫チェックポイント阻害薬 / 腫瘍免疫 / NELL2 / Tステムセル / Tステムメモリー細胞 / CD8陽性T細胞 / CAR-T / 腫瘍浸潤T細胞 / Tステムセルメモリー細胞 / シングルセル解析 / 免疫チェックポイント阻害剤 Less
  • Research Projects

    (6 results)
  • Research Products

    (25 results)
  • Co-Researchers

    (6 People)
  •  長鎖非コード RNA CASC によるヒト CD4+T 細胞の代謝制御を介した抗腫瘍活性の増強Principal Investigator

    • Principal Investigator
      三沢 彩
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      International University of Health and Welfare
  •  Identification of novel targets for cancer immunotherapy through investigation of statins` lipid modulating activities on anti-tumor T cells

    • Principal Investigator
      CHAW KYI.THA.THU
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      International University of Health and Welfare
  •  免疫チェックポイント阻害剤応答性細胞集団に発現する新規機能分子の解析

    • Principal Investigator
      大多 茂樹
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      International University of Health and Welfare
  •  Functional analysis of prostate cancer bone metastasis-related lncRNA and establishment of the basis for the development of new therapiesPrincipal Investigator

    • Principal Investigator
      Misawa Aya
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      International University of Health and Welfare
      Keio University
      Nippon Medical School
  •  Analysis of epigenetic regulation of androgen responsive miRNAs in prostate cancerPrincipal Investigator

    • Principal Investigator
      Misawa Aya
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Tumor biology
    • Research Institution
      Nippon Medical School
  •  Oncomir miR-21による癌幹細胞の制御機構の解明Principal Investigator

    • Principal Investigator
      三沢 彩
    • Project Period (FY)
      2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Tumor biology
    • Research Institution
      The University of Tokyo

All 2024 2023 2022 2021 2019 2018 2017 2016 2012

All Journal Article Presentation

  • [Journal Article] Melanoma antigens recognized by T cells and their use for immunotherapy2022

    • Author(s)
      Shigeki Ohta, Aya Misawa, Chaw Kyi-Tha-Thu, Naomi Matsumoto, Yoshie Hirose, Yutaka Kawakami
    • Journal Title

      Exp Dermatol

      Volume: 32(3) Issue: 3 Pages: 297-305

    • DOI

      10.1111/exd.14741

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07199, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20H03534, KAKENHI-PROJECT-18K09181
  • [Journal Article] Long Noncoding RNA HOXA11-AS and Transcription Factor HOXB13 Modulate the Expression of Bone Metastasis-Related Genes in Prostate Cancer2021

    • Author(s)
      Aya Misawa, Yukihiro Kondo, Hiroyuki Takei and Toshihiro Takizawa
    • Journal Title

      Genes

      Volume: 12(182) Issue: 2 Pages: 1-19

    • DOI

      10.3390/genes12020182

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09181, KAKENHI-PROJECT-18K08583, KAKENHI-PROJECT-20K09588
  • [Journal Article] Androgen-induced lncRNA POTEF-AS1 regulates apoptosis-related pathway to facilitate cell survival in prostate cancer cells.2017

    • Author(s)
      Misawa A, Takayama KI, Fujimura T, Homma Y, Suzuki Y, Inoue S
    • Journal Title

      Cancer Sci

      Volume: 108(3) Issue: 3 Pages: 373-379

    • DOI

      10.1111/cas.13151

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15353, KAKENHI-PROJECT-15K10576, KAKENHI-PROJECT-15K15581, KAKENHI-PROJECT-16K18411
  • [Journal Article] Androgen-induced lncRNA SOCS2-AS1 promotes cell growth and inhibits apoptosis in prostate cancer cells.2016

    • Author(s)
      Misawa A, Takayama K, Urano T, Inoue S
    • Journal Title

      J Biol Chem

      Volume: 291(34) Issue: 34 Pages: 17861-17880

    • DOI

      10.1074/jbc.m116.718536

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15353, KAKENHI-PROJECT-16K09796, KAKENHI-PROJECT-15K15581, KAKENHI-PROJECT-16K15496, KAKENHI-PROJECT-16K18411
  • [Presentation] Statin improve anti-tumor effects of anti-PD-1 antibody through preventing CD8+T cell exhaustion via modulating lipid metabolism2024

    • Author(s)
      Chaw KT, Tsubota K, Yaguchi T, Misawa A, Ohta S, Kawakami Y
    • Organizer
      第52回日本免疫学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07199
  • [Presentation] Cancer derived blood EVs potential predictive biomarkers for NSCLC patients treated with anti-PD-1 antibody2024

    • Author(s)
      Ohta S, Kinoshita T, Wakui S, Maeda C, Hayahsi Y, Misawa A, Satomi R, Ikemura S, Soezima K, Yaguchi T, Kagamu K, Kawakami Y
    • Organizer
      The 1st international Symposium on Cancer Immunology and Immunotherapy
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07199
  • [Presentation] Cancer derived plasma exosomes are potential predictive biomarkers for NSCLC patients treated with anti-PD-1 antibod2023

    • Author(s)
      Ohta S, Kinoshita T, Wakui S, Maeda C, Hayahsi Y, Misawa A, Satomi R, Ikemura S, Soezima K, Yaguchi T, Kagamu K, Kawakami Y
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07199
  • [Presentation] 抗PD-1抗体の治療奏効と相関するCASCはT細胞代謝を制御する2023

    • Author(s)
      三沢彩、大多茂樹、池本篤史、滝本哲也、河上裕
    • Organizer
      第27回 日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-21K07199
  • [Presentation] 非小細胞肺癌患者における血漿中の腫瘍由来 細胞外小胞の測定~術後予後と抗PD-1抗体治療効果の予測法2023

    • Author(s)
      木下智成、大多茂樹、和久井世紀、谷口智憲、三沢彩、前田智早、副島研造、河上裕
    • Organizer
      第64回日本肺癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K07199
  • [Presentation] CASCはT細胞代謝を制御し、抗PD-1抗体の治療奏効と相関する2023

    • Author(s)
      三沢彩、大多茂樹、池本篤史、滝本哲也、河上裕
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07199
  • [Presentation] Cancer derived blood exosomes are potential predictive biomarkers for NSCLC patients treated with anti-PD-1 antibody2023

    • Author(s)
      Ohta S, Kinoshita T, Wakui S, Maeda C, Hayahsi Y, Misawa A, Satomi R, Ikemura S, Soezima K, Yaguchi T, Kagamu K, Kawakami Y
    • Organizer
      2nd JCA-AACR Precision Cancer Medicine International Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07199
  • [Presentation] Serine threonine kinase 24 (STK24) mediates immune evasion signals in tumors by inducing multiple immunosuppressive molecules2022

    • Author(s)
      Misawa A, Ohta S, Imagawa R, Katoh Y, Sumimoto H, Goto- Matsumoto N, Nakamura K, Okuyama R, Kawakami Y
    • Organizer
      第51回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K07199
  • [Presentation] CASC may be involved in anti-tumor immune response through the modulation of NAD+ dependent energy metabolism2022

    • Author(s)
      三沢 彩, 大多 茂樹, 池田 篤史, 滝本 哲也, チョー チータートゥー, 河上 裕
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07199
  • [Presentation] CASC may be involved in anti-tumor immune response through the modulation of NAD+ dependent energy metabolism2022

    • Author(s)
      Aya Misawa
    • Organizer
      第81回日本癌学会
    • Data Source
      KAKENHI-PROJECT-18K09181
  • [Presentation] 胃がんにおける複合がん免疫療法効果予測のためのバイオマーカー候補の同定2021

    • Author(s)
      大多 茂樹、伊澤 直樹 、三沢 彩、加藤 侑希、久保 亜紀子 、門脇 重憲、三梨 桂子、仁科 智裕、中島 貴子、河上 裕
    • Organizer
      日本癌学会、第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07199
  • [Presentation] 癌の骨転移に関与する lncRNA の分子解剖学的解析2019

    • Author(s)
      三沢彩、近藤幸尋、武井寛幸、瀧澤俊広
    • Organizer
      第124回日本解剖学会総会全国学術集会
    • Data Source
      KAKENHI-PROJECT-18K09181
  • [Presentation] 癌の骨転移に関与する lncRNA の分子解剖学的解析2019

    • Author(s)
      三沢彩、近藤幸尋、武井寛幸、瀧澤俊広
    • Organizer
      124回日本解剖学会
    • Data Source
      KAKENHI-PROJECT-16K18411
  • [Presentation] 分子解剖学的アプローチによる癌の骨転移における HOXA11-AS の機能解明2019

    • Author(s)
      三沢彩、近藤幸尋、武井寛幸、瀧澤俊広
    • Organizer
      第125回日本解剖学会総会全国学術集会
    • Data Source
      KAKENHI-PROJECT-18K09181
  • [Presentation] 癌の骨転移に関与する lncRNA の機能解析2019

    • Author(s)
      三沢彩、近藤幸尋、武井寛幸、瀧澤俊広
    • Organizer
      第78回日本癌学会
    • Data Source
      KAKENHI-PROJECT-18K09181
  • [Presentation] ヒト骨肉腫細胞における HOTAIR による ALPL のエピジェネティックな制御機構の解析2018

    • Author(s)
      三沢 彩
    • Organizer
      2017年度生命科学系学会合同年次大会
    • Data Source
      KAKENHI-PROJECT-16K18411
  • [Presentation] 前立腺癌の骨転移に関与する lncRNA の同定及び機能解析2018

    • Author(s)
      三沢彩、瀧澤俊広
    • Organizer
      第77回日本癌学会
    • Data Source
      KAKENHI-PROJECT-16K18411
  • [Presentation] ヒト骨肉腫細胞における lncRNA による ALPL のエピジェネティック制御機構の解析2018

    • Author(s)
      三沢 彩
    • Organizer
      第12回 ALPS 研究会
    • Data Source
      KAKENHI-PROJECT-16K18411
  • [Presentation] ヒト骨芽細胞様骨肉腫細胞における HOTAIR による ALPL のエピジェネティックな制御機構の解析2018

    • Author(s)
      三沢 彩
    • Organizer
      第123回日本解剖学会総会全国学術集会
    • Data Source
      KAKENHI-PROJECT-16K18411
  • [Presentation] 前立腺癌の骨転移に関与する lncRNA の同定及び機能解析2018

    • Author(s)
      三沢彩、瀧澤俊広
    • Organizer
      第77回日本癌学会
    • Data Source
      KAKENHI-PROJECT-18K09181
  • [Presentation] 次世代シーケンサーを用いた前立腺がん細胞株におけるmiRNAの発現解析2012

    • Author(s)
      三沢彩
    • Organizer
      第12回関東ホルモンと癌研究会
    • Place of Presentation
      東京大学山上会館
    • Year and Date
      2012-01-21
    • Data Source
      KAKENHI-PROJECT-23701064
  • 1.  大多 茂樹 (20365406)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 11 results
  • 2.  河上 裕 (50161287)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 11 results
  • 3.  CHAW KYI.THA.THU (00792417)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  瀧澤 俊広 (90271220)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 5.  岩田 卓 (30296652)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  井上 聰
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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