Kuboyama Kazuya 久保山和哉

… Alternative Names

久保山和哉クボヤマカズヤ

KUBOYAMA Kazuya 久保山和哉

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Researcher Number	20619671
Other IDs
Affiliation (Current)	2025: 名古屋市立大学, 医薬学総合研究院(医学), 助教
Affiliation (based on the past Project Information) *help	2023: 名古屋市立大学, 医薬学総合研究院(医学), 助教 2017 – 2019: 徳島文理大学, 薬学部, 助教 2014 – 2015: 基礎生物学研究所, 統合神経生物学研究部門, 特別協力研究員 2012 – 2013: 基礎生物学研究所, 統合神経生物学研究部門, NIBBリサーチフェロー
Review Section/Research Field	Principal Investigator Basic Section 44010:Cell biology-related / Functional biochemistry / Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology
Keywords	Principal Investigator プロテインチロシンホスファターゼ / チロシンリン酸化 / 脱髄疾患 / グリア細胞 / オリゴデンドロサイト / 脳・神経 / 神経科学 / チロシンホスファターゼ / タンパク質チロシンリン酸化シグナル / 裏打ちタンパク質 … More / 生後脳におけるニューロン新生 / コンディショナル・ノックアウトマウス / 細胞接着分子 / 細胞間相互作用 / ニューロン移動 / 糖鎖生物学 / 神経化学・神経薬理学 / プロタミン / コンドロイチン硫酸プロテオグリカン / AKT / AFAP1L2 / OL1細胞 / 糖鎖 / タンパク質チロシン脱リン酸化酵素 / 動物行動学 / OPCs / PTPRZ / コンドロイチン硫酸糖鎖 / コンドロイチン硫酸プロテオグリカン（CSPG） / 細胞分化 / Rho / 蛋白質チロシン脱リン酸化酵素 / 蛋白質チロシンリン酸化酵素 Less

Molecular mechanism for the regulation of neuroblast chain migration by the cell adhesion molecule.Principal Investigator
- Principal Investigator
  
  久保山和哉
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Nagoya City University
Determination of the proteoglycans to the oligodendrocyte differentiationPrincipal Investigator
- Principal Investigator
  
  Kuboyama Kazuya
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokushima Bunri University
Determination of the receptor type protein tyrosine phosphatase of to the oligodendrocyte differentiationPrincipal Investigator
- Principal Investigator
  
  KUBOYAMA Kazuya
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  National Institute for Basic Biology
Determination of the tyrosine phosphorylation signaling to regulate the oligodendrocyte differentiation.Principal Investigator
- Principal Investigator
  
  KUBOYAMA Kazuya
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  National Institute for Basic Biology

All 2024 2020 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Identification of the growth cone as a probe and driver of neuronal migration in the injured brain2024
- Author(s)
  Nakajima C、Sawada M、Umeda E、Takagi Y、Nakashima N、Kuboyama K、Kaneko N、Yamamoto S、Nakamura H、Shimada N、Nakamura K、Matsuno K、Uesugi S、Veprek NA、Kuellmer F、Nasufovic V、Uchiyama H、Nakada M、Otsuka Y、Ito Y、Herranz-Perez V、Garcia-Verdugo JM、Ohno N、Arndt H-D、Trauner D、Tabata Y、Igarashi M、Sawamoto K
- Journal Title
  
  Nature Communications
  
  Volume: 15 Issue: 1 Pages: 1877-1877
- DOI
  10.1038/s41467-024-45825-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K19406, KAKENHI-PROJECT-23K05770, KAKENHI-PROJECT-21K06395, KAKENHI-PLANNED-21H05106, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-20H05700, KAKENHI-PROJECT-23K27270
[Journal Article] Behavioral and neurological analyses of adult mice carrying null and distinct loss-of-receptor function mutations in protein tyrosine phosphatase receptor type Z (PTPRZ)2019
- Author(s)
  Tanga Naomi、Kuboyama Kazuya、Kishimoto Ayako、Kihara Miho、Kiyonari Hiroshi、Watanabe Toshio、Fujikawa Akihiro、Noda Masaharu
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 6 Pages: e0217880-e0217880
- DOI
  10.1371/journal.pone.0217880
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07069, KAKENHI-PROJECT-17K07355
[Journal Article] A head-to-toe dimerization has physiological relevance for ligand-induced inactivation of protein tyrosine receptor type Z2019
- Author(s)
  Fujikawa Akihiro、Sugawara Hajime、Tanga Naomi、Ishii Kentaro、Kuboyama Kazuya、Uchiyama Susumu、Suzuki Ryoko、Noda Masaharu
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 294 Issue: 41 Pages: 14953-14965
- DOI
  10.1074/jbc.ra119.007878
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H04555, KAKENHI-PROJECT-17K07069, KAKENHI-PROJECT-17K07355, KAKENHI-PROJECT-19H05659
[Journal Article] PI3K‐AKT pathway for oligodendrocyte differentiation: Targeted inactivation of PTPRZ activity in mice2018
- Author(s)
  Naomi Tanga, Kazuya Kuboyama, Ayako Kishimoto, Hiroshi Kiyonari, Aki Shiraishi, Ryoko Suzuki, Toshio Watanabe, Akihiro Fujikawa, and Masaharu Noda
- Journal Title
  
  Glia
  
  Volume: 67 Issue: 5 Pages: 967-984
- DOI
  10.1002/glia.23583
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07069, KAKENHI-PROJECT-17K07355, KAKENHI-PROJECT-16K07296
[Journal Article] Enhanced extinction of aversive memories in mice lacking SPARC-related protein-containing immunoglobulin domains 1 (SPIG1/FSTL4).2018
- Author(s)
  Ryoko Suzuki, Akihiro Fujikawa, Yukio Komatsu, Kazuya Kuboyama, Naomi Tanga, Masaharu Noda
- Journal Title
  
  Neurobiology of learning and memory
  
  Volume: 152 Pages: 61-61
- DOI
  10.1016/j.nlm.2018.05.010
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07355, KAKENHI-PROJECT-18K06475
[Journal Article] Identification of novel splicing variants of protein tyrosine phosphatase receptor type Z2017
- Author(s)
  Fujikawa Akihiro、Chow Jeremy Pak Hong、Matsumoto Masahito、Suzuki Ryoko、Kuboyama Kazuya、Yamamoto Naoki、Noda Masaharu
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 162 Issue: 5 Pages: 381-390
- DOI
  10.1093/jb/mvx042
- NAID
  40021394892
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07069, KAKENHI-PROJECT-17K07355, KAKENHI-PROJECT-17K11495
[Journal Article] Protamine neutralizes chondroitin sulfate proteoglycan-mediated inhibition of oligodendrocyte differentiation2017
- Author(s)
  Kuboyama Kazuya、Tanga Naomi、Suzuki Ryoko、Fujikawa Akihiro、Noda Masaharu
- Journal Title
  
  Plos One
  
  Volume: 12 Issue: 12 Pages: e0189164-e0189164
- DOI
  10.1371/journal.pone.0189164
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07355
[Journal Article] Targeting PTPRZ inhibits stem cell-like properties and tumorigenicity in glioblastoma cells2017
- Author(s)
  Fujikawa Akihiro、Sugawara Hajime、Tanaka Taisaku、Matsumoto Masahito、Kuboyama Kazuya、Suzuki Ryoko、Tanga Naomi、Ogata Atsuto、Masumura Makoto、Noda Masaharu
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 5609-5609
- DOI
  10.1038/s41598-017-05931-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07355
[Journal Article] Small-molecule inhibition of PTPRZ reduces tumor growth in a rat model of glioblastoma.2016
- Author(s)
  Fujikawa A, Nagahira A, Sugawara H, Ishii K, Imajo S, Matsumoto M, Kuboyama K, Suzuki R, Tanga N, Noda M, Uchiyama S, Tomoo T, Ogata A, Masumura M, Noda M.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 20473-20473
- DOI
  10.1038/srep20473
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-26102530, KAKENHI-PROJECT-26830050
[Journal Article] Specific dephosphorylation at tyr-554 of git1 by ptprz promotes its association with paxillin and hic-5.2015
- Author(s)
  Fujikawa A, Matsumoto M, Kuboyama K, Suzuki R, Noda M.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 3 Pages: 1-20
- DOI
  10.1371/journal.pone.0119361
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26830050, KAKENHI-PUBLICLY-26110722
[Journal Article] Channel properties of Nax expressed in neurons.2015
- Author(s)
  Matsumoto M, Hiyama TY, Kuboyama K, Suzuki R, Fujikawa A, Noda M.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 5 Pages: e0126109-e0126109
- DOI
  10.1371/journal.pone.0126109
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-26111726, KAKENHI-PROJECT-26830050, KAKENHI-PROJECT-26293043, KAKENHI-PROJECT-24220010
[Journal Article] Loss of Function Mutation in APC2 Causes Sotos Syndrome Features.2015
- Author(s)
  Almuriekhi, M., Shintani, T., Fahiminiya, S., Fujikawa, A., Kuboyama, K., Takeuchi, Y., Nawaz, Z., Nadaf, J., Kamel, H., Kitam, A.K., Samiha, Z., Mahmoud, L., Ben-Omran, T., Majewski, J. & Noda, M.
- Journal Title
  
  Cell Reports
  
  Volume: 10 Issue: 9 Pages: 1585-1598
- DOI
  10.1016/j.celrep.2015.02.011
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24650174, KAKENHI-PUBLICLY-25123720, KAKENHI-PROJECT-26830050
[Journal Article] Inactivation of protein tyrosine phosphatase receptor type Z by pleiotrophin promotes remyelination through activation of differentiation of oligodendrocyte precursor cells2015
- Author(s)
  Kuboyama, K., Fujikawa, A., Suzuki, R., and Noda, M
- Journal Title
  
  J. Neurosci.
  
  Volume: 35 Issue: 35 Pages: 12162-12171
- DOI
  10.1523/jneurosci.2127-15.2015
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-26110722, KAKENHI-PROJECT-26830050
[Journal Article] SPIG1 negatively regulates BDNF maturation2014
- Author(s)
  Suzuki R, Matsumoto M, Fujikawa A, Kato A, Kuboyama K, Yonehara K, Shintani T, Sakuta H, Noda M
- Journal Title
  
  J. Neurosci
  
  Volume: 34 Issue: 9 Pages: 3429-3442
- DOI
  10.1523/jneurosci.1597-13.2014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300126, KAKENHI-PROJECT-24500390, KAKENHI-PROJECT-24650174, KAKENHI-PROJECT-24700387, KAKENHI-PUBLICLY-25123720
[Journal Article] Protein tyrosine phosphatase receptor type Z negatively regulates oligodendrocyte differentiation and myelination.2012
- Author(s)
  Kuboyama, et al.
- Journal Title
  
  PLoS ONE
  
  Volume: 7(11) Issue: 11 Pages: 1-11
- DOI
  10.1371/journal.pone.0048797
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0317, KAKENHI-PROJECT-24500390, KAKENHI-PROJECT-24700387
[Journal Article] SAP97 promotes the stability of Nax channels at the plasma membrane2012
- Author(s)
  Matsumoto M 他
- Journal Title
  
  FEBS Lett
  
  Volume: 586 Issue: 21 Pages: 3805-3812
- DOI
  10.1016/j.febslet.2012.09.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0317, KAKENHI-PROJECT-24220010, KAKENHI-PROJECT-24500390, KAKENHI-PROJECT-24689013, KAKENHI-PROJECT-24700387, KAKENHI-PUBLICLY-24111549
[Presentation] 傷害脳内のニューロン移動を制御する成長円錐の同定2024
- Author(s)
  中嶋智佳子, 澤田雅人, 梅田恵里花, 高木佑真, 中島徳彦, 久保山和哉他22名
- Organizer
  第17回神経発生討論会・第20回成体脳のニューロン新生懇談会合同大会
- Data Source
  KAKENHI-PROJECT-23K05770
[Presentation] 体性感覚刺激入力によるNMDA型受容体依存的な大脳皮質樹状突起スパイン分子の可塑的変化2020
- Author(s)
  久保山和哉, 井上貴文, 橋本谷祐輝, 伊藤拓矢, 鈴木東介, 鉄澤愛彩, 木下諒, 大塚庸介, 高良廉, 宮澤徹, Pooja Gusain, 多和田真聖, 狩野方伸, 山田麻紀
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17K07355
[Presentation] 大脳皮質シナプス・スパインの可塑的変化を蛍光標識するためのAiCEマウスの作製とその基礎的解析2019
- Author(s)
  鈴木東介, 久保山和哉, 橋本谷祐輝, 大塚庸介, Gusain Pooja, 狩野方伸, 山田麻紀
- Organizer
  第58回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-17K07355
[Presentation] AiCEマウス：入力依存的なスパインの変化を検出する新規ツール2019
- Author(s)
  久保山和哉, 井上貴文, 橋本谷祐輝, 伊藤拓矢, 鈴木東介, 大塚庸介, 木下諒, Pooja Gusain, 狩野方伸, 岡部繁男, 山田麻紀
- Organizer
  NEURO2019
- Data Source
  KAKENHI-PROJECT-17K07355
[Presentation] AiCEマウスで可視化した感覚刺激入力後大脳皮質におけるスパイン可塑的変化2019
- Author(s)
  伊藤拓矢, 久保山和哉, 井上貴文, 高良廉, 宮澤徹, 鉄澤愛彩, 木下諒, 山田麻紀
- Organizer
  第58回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-17K07355
[Presentation] AiCEマウスを用いた片側感覚刺激後における左右半球比較による樹状突起スパインの可塑的変化の観察2019
- Author(s)
  宮澤徹, 久保山和哉, 井上貴文, 橋本谷祐輝, 伊藤拓矢, 鈴木東介, 鉄澤愛彩, 木下諒, 大塚庸介, 高良廉, Gusain Pooja, 多和田真聖, 狩野方伸, 山田麻紀
- Organizer
  第136回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-17K07355
[Presentation] ラット非観血式血圧測定法によるアクティブ・ラーニングを促す謎解き型薬理学実習2018
- Author(s)
  久保山和哉, 鈴木東介, 大塚庸介, 伊藤拓哉, 木下諒, 田中智大, 鉄澤愛彩, 山田麻紀
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K07355
[Presentation] コンドロイチン硫酸糖鎖によるオリゴデンドロサイト分化の抑制をプロタミンは中和する2018
- Author(s)
  久保山和哉, 藤川顕寛, 丹賀直美, 鈴木亮子, 野田昌晴
- Organizer
  第133回薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-17K07355
[Presentation] Protamine neutralizes chondroitin sulfate proteoglycan-mediated inhibition of oligodendrocyte differentiation2018
- Author(s)
  Kazuya Kuboyama, Naomi Tanga, Ryoko Suzuki, Akihiro Fujikawa, Masaharu Noda
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17K07355
[Presentation] Role of Chondroitin Sulfate (CS) Modification in the Regulation of Protein-tyrosine Phosphatase Receptor Type Z (PTPRZ) Activity: pleiotrophin-PTPRZ-A signaling is involved in oligodendrocyte differentiation2017
- Author(s)
  Kuboyama Kazuya、Tanga Naomi、Suzuki Ryoko、Fujikawa Akihiro、Noda Masaharu
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17K07355
[Presentation] pleiotrophin-PTPRZシグナルによるオリゴデンドロサイトの分化と再ミエリン化の制御機構2016
- Author(s)
  久保山和哉, 藤川顕寛, 鈴木亮子, 野田昌晴
- Organizer
  第7回日本プロテインホスファターゼ研究会学術集会
- Place of Presentation
  自然科学研究機構（愛知県岡崎市）
- Year and Date
  2016-01-29
- Data Source
  KAKENHI-PROJECT-26830050
[Presentation] Loss-of-Function Mutation in APC2 Causes Sotos Syndrome Features.2015
- Author(s)
  新谷隆史, Fahiminiya S, Almuriekhi M, 藤川顕寛, 久保山和哉, 竹内靖, Nawaz Z, Nadaf J, Kamel H, Kitam KA, Samiha Z, Mahmoud L, Ben-Omran T, Majewski J, 野田昌晴
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-26830050
[Presentation] Role of Pleiotrophin-PTPRZ Signaling in Oligodendrocyte Differentiation and Remyelination.2015
- Author(s)
  久保山和哉, 藤川顕寛, 鈴木亮子, 野田昌晴
- Organizer
  第88回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26830050
[Presentation] Phosphorylation of Git1 at Tyrosine 554 Negatively Regulates Association with Hic-5 and Paxillin2014
- Author(s)
  藤川顕寛,松本匡史,久保山和哉,鈴木亮子,野田昌晴
- Organizer
  第6回日本プロテインホスファターゼ研究会学術集会
- Place of Presentation
  津
- Data Source
  KAKENHI-PROJECT-24700387
[Presentation] Phosphorylation of Git1 at Tyrosine 554 Negatively Regulates Association with Hic-5 and Paxillin2014
- Author(s)
  藤川顕寛, 松本匡史, 久保山和哉, 鈴木亮子, 野田昌晴
- Organizer
  第６回日本プロテインホスファターゼ研究会学術集会
- Place of Presentation
  三重大学 (三重県津市)
- Data Source
  KAKENHI-PROJECT-24700387
[Presentation] Protein Tyrosine Phosphatase Receptor Type Z Negatively Regulates Oligodendrocyte Differentiation and Myelination2013
- Author(s)
  Kazuya Kuboyama, Akihiro Fujikawa, Makoto Masumura, Ryoko Suzuki, Masahito Matsumoto, Masaharu Noda
- Organizer
  10th International Conference on Protein Phosphatase Protein Phosphatases and Diseases
- Place of Presentation
  がん研究振興財団国際研究交流会館 (東京都中央区)
- Data Source
  KAKENHI-PROJECT-24700387
[Presentation] Protein Tyrosine Phosphatase Receptor Type Z Negatively Regulates Oligodendrocyte Differentiation and Myelination2013
- Author(s)
  Kuboyama K, Fujikawa A, Masumura M, Suzuki R, Matsumoto M, and Noda M.
- Organizer
  10th International Conference on Protein Phosphatase Protein Phosphatases and Diseases
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-24700387
[Presentation] Protein Tyrosine Phosphatase Receptor Type Z Negatively Regulates Oligodendrocyte Differentiation and Myelination2013
- Author(s)
  Kuboyama K.
- Organizer
  The 2nd Taiwan-Japan Bilateral Conference on Protein Phosphatases
- Place of Presentation
  National Health Research Institutes (Taiwan)
- Invited
- Data Source
  KAKENHI-PROJECT-24700387
[Presentation] Protein tyrosine phosphatase receptor type Z negatively regulates oligodendrocyte differentiation and myelination2013
- Author(s)
  Kuboyama K.
- Organizer
  The 2nd Taiwan-Japan Bilateral Conference on Protein Phosphatases
- Place of Presentation
  Taipei, Taiwan
- Invited
- Data Source
  KAKENHI-PROJECT-24700387
[Presentation] SAP97は細胞表面におけるNaxチャンネルの安定性を促進する2012
- Author(s)
  松本匡史, 藤川顕寛, 鈴木亮子, 清水秀忠, 久保山和哉, 檜山武史, Randy Hall, 野田昌晴
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場、マリンメッセ福岡 (福岡県福岡市)
- Data Source
  KAKENHI-PROJECT-24700387
[Presentation] SAP97は細胞表面におけるNaxチャンネルの安定性を促進する2012
- Author(s)
  松本匡史,藤川顕寛,鈴木亮子,清水秀忠,久保山和哉,檜山武史, Randy Hall,野田昌晴
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24700387
[Presentation] Mice deficient in Protein Tyrosine Phosphatase Receptor Type Z Show Resistance to Experimental Autoimmune Encephalomyelitis2012
- Author(s)
  久保山和哉,藤川顕寛,升村誠,鈴木亮子,松本匡史,野田昌晴
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24700387
[Presentation] Ptprz欠損マウスは実験的自己免疫性脳脊髄炎に抵抗性である2012
- Author(s)
  久保山和哉, 藤川顕寛, 升村誠, 鈴木亮子, 松本匡史, 野田昌晴
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場、マリンメッセ福岡 (福岡県福岡市)
- Data Source
  KAKENHI-PROJECT-24700387
[Presentation] Mice deficient in protein tyrosine phosphatase receptor type Z show resistance to experimental autoimmune encephalomyelitis2012
- Author(s)
  久保山和哉,藤川顕寛,升村誠,鈴木亮子,松本匡史,野田昌晴
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24700387
[Presentation] Ptprz欠損マウスは実験的自己免疫性脳脊髄炎に抵抗性である2012
- Author(s)
  久保山和哉, 藤川顕寛, 升村誠, 鈴木亮子, 松本匡史, 野田昌晴
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋国際会議場 (愛知県名古屋市)
- Data Source
  KAKENHI-PROJECT-24700387
[Presentation] Specific dephosphorylation at Tyr-554 of Git1 by Ptprz promotes its association with paxillin and Hic-5.
- Author(s)
  Fujikawa A, Matsumoto M, Kuboyama K, Suzuki R, Noda M.
- Organizer
  第11回プロテインホスファターゼ国際カンファレンス
- Place of Presentation
  東北大学医学部艮陵会館 (宮城県仙台市)
- Year and Date
  2014-11-12 – 2014-11-14
- Data Source
  KAKENHI-PROJECT-26830050

1. FUJIKAWA Akihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
2. 新谷隆史

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. 檜山武史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 内山進

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 中嶋智佳子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kuboyama Kazuya 久保山 和哉

久保山 和哉 クボヤマ カズヤ

KUBOYAMA Kazuya 久保山 和哉

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Molecular mechanism for the regulation of neuroblast chain migration by the cell adhesion molecule.Principal Investigator

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Determination of the proteoglycans to the oligodendrocyte differentiationPrincipal Investigator

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Determination of the receptor type protein tyrosine phosphatase of to the oligodendrocyte differentiationPrincipal Investigator

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Determination of the tyrosine phosphorylation signaling to regulate the oligodendrocyte differentiation.Principal Investigator

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[Journal Article] Identification of the growth cone as a probe and driver of neuronal migration in the injured brain2024

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[Journal Article] Behavioral and neurological analyses of adult mice carrying null and distinct loss-of-receptor function mutations in protein tyrosine phosphatase receptor type Z (PTPRZ)2019

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[Journal Article] A head-to-toe dimerization has physiological relevance for ligand-induced inactivation of protein tyrosine receptor type Z2019

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[Journal Article] PI3K‐AKT pathway for oligodendrocyte differentiation: Targeted inactivation of PTPRZ activity in mice2018

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[Journal Article] Enhanced extinction of aversive memories in mice lacking SPARC-related protein-containing immunoglobulin domains 1 (SPIG1/FSTL4).2018

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[Journal Article] Identification of novel splicing variants of protein tyrosine phosphatase receptor type Z2017

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NAID

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[Journal Article] Protamine neutralizes chondroitin sulfate proteoglycan-mediated inhibition of oligodendrocyte differentiation2017

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[Journal Article] Targeting PTPRZ inhibits stem cell-like properties and tumorigenicity in glioblastoma cells2017

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[Journal Article] Small-molecule inhibition of PTPRZ reduces tumor growth in a rat model of glioblastoma.2016

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[Journal Article] Specific dephosphorylation at tyr-554 of git1 by ptprz promotes its association with paxillin and hic-5.2015

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Kuboyama Kazuya 久保山和哉

久保山和哉クボヤマカズヤ

KUBOYAMA Kazuya 久保山和哉