KAWASHIMA Ichiro 川島一郎

… Alternative Names

川島一郎カワシマイチロウ

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Researcher Number	20622369
Other IDs
Affiliation (Current)	2025: 山梨大学, 大学院総合研究部, 准教授
Affiliation (based on the past Project Information) *help	2024: 山梨大学, 大学院総合研究部, 助教 2017 – 2020: 山梨大学, 大学院総合研究部, 助教 2015 – 2016: 山梨大学, 総合研究部, 助教
Review Section/Research Field	Except Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Hematology
Keywords	Except Principal Investigator JAK2V617F / GRP78 / 骨髄増殖性腫瘍 / Lysyl oxidase / ERストレス / lysyl oxidase / metformin / 組織因子 / 血栓 / メトホルミン … More / 分子シャペロン / UPR / TIMP / MMP / SAPK/JNK / type1 コラーゲン / 骨髄間質細胞 / MMP9 / ATF4 / 骨髄線維症 / 小胞体ストレス / MCT / 乳酸 / 骨髄線維化 / 低酸素 / 活性酸素 / 糖代謝 / 線維化 / PP2A / myelofibrosis Less

GRP78の発現異常は骨髄増殖性腫瘍の血栓性病態を誘導するか？
- Principal Investigator
  
  桐戸敬太
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  University of Yamanashi
Enhanced ER stress response in MPN cells involved in development of myelofibrosis through secretion of GRP78
- Principal Investigator
  
  KIRITO Keita
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  University of Yamanashi
Role of glucose metabolism in development of myelofibrosis
- Principal Investigator
  
  KIRITO Keita
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  University of Yamanashi

All 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Bone Marrow Invasion of Small Cell Neuroendocrine Carcinoma of the Endometrium: A Diagnostic Pitfall Mimicking a Haematological Malignancy2019
- Author(s)
  Kawashima Ichiro、Fukasawa Hiroko、Kasai Kazunari、Kumagai Takuma、Koshiishi Megumi、Nakajima Kei、Kondo Tetsuo、Hashi Akihiko、Hirata Shuji、Kirito Keita
- Journal Title
  
  Intern. Med.
  
  Volume: 58 Issue: 17 Pages: 2561-2568
- DOI
  10.2169/internalmedicine.2533-18
- NAID
  130007700192
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2019-09-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08319
[Journal Article] Glycolytic enzyme hexokinase II is a putative therapeutic target in B-cell malignant lymphoma2019
- Author(s)
  Nakajima Kei、Kawashima Ichiro、Koshiisi Megumi、Kumagai Takuma、Suzuki Megumi、Suzuki Jun、Mitsumori Toru、Kirito Keita
- Journal Title
  
  Experimental Hematology
  
  Volume: 78 Pages: 46-55.e3
- DOI
  10.1016/j.exphem.2019.09.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08319, KAKENHI-PROJECT-19K17826
[Journal Article] Molecular response of CSF3R T618I harboring chronic neutrophilic leukemia after induction chemotherapy linked to cord blood transplantation2019
- Author(s)
  Kawashima Ichiro、Kumagai Takuma、Suzuki Megumi、Suzuki Jun、Koshiishi Megumi、Nakajima Kei、Kirito Keita
- Journal Title
  
  Annals of Hematology
  
  Volume: 98 Issue: 9 Pages: 2249-2250
- DOI
  10.1007/s00277-019-03733-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08319
[Journal Article] Metformin inhibits JAK2V617F activity in MPN cells by activating AMPK and PP2A complexes containing the B56alpha subunit2016
- Author(s)
  Kawashima I, Kirito K
- Journal Title
  
  Experimental Hematology
  
  Volume: 44 Issue: 12 Pages: 1156-1165
- DOI
  10.1016/j.exphem.2016.08.005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09470
[Journal Article] Negative regulation of the LKB1/AMPK pathway by ERK in human acute myeloid leukemia cells2015
- Author(s)
  Kawashima, I. Mitsumori, T. Nozaki, Y. Yamamoto, T. Shobu-Sueki, Y. Nakajima, K. Kirito, K.
- Journal Title
  
  Exp Hematol
  
  Volume: in press Issue: 7 Pages: 524-533.e1
- DOI
  10.1016/j.exphem.2015.03.005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591386, KAKENHI-PROJECT-15K09470
[Presentation] 骨髄増殖腫瘍における18F-FDG-PET/CT所見2019
- Author(s)
  鈴木潤、佐藤葉子、輿石めぐみ、鈴木愛、川島一郎、中嶌圭、桐戸敬太
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08319
[Presentation] APL細胞の細胞表面マーカーの特徴と限界2019
- Author(s)
  細川恵理子, 輿石めぐみ, 鈴木潤, 熊谷拓磨, 鈴木愛, 川島一郎, 中島圭, 桐戸敬太
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08319
[Presentation] 日本における二次性骨髄線維症の予後予測モデルの比較検討2019
- Author(s)
  鈴木愛、鈴木潤、輿石めぐみ、川島一郎、中嶌圭、三森徹、桐戸敬太
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08319
[Presentation] CSF3RT618I変異検出により診断することができた慢性好中球性白血病2019
- Author(s)
  川島一郎、鈴木潤、熊谷琢磨、鈴木愛、輿石めぐみ、中嶌圭、桐戸敬太
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08319
[Presentation] Metformin suppresses expression of pre-fibrotic Enzyme Lysyl-oxidase levels through Inhibition of UPR in MPN cells2018
- Author(s)
  Megumi Suzuki, Jun Shuzuki, Megumi Koshiishi, Ichiro kawashima, Kei Nakajima, Keita Kirito
- Organizer
  第60回米国血液学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08319
[Presentation] Metformin suppresses expression of pre-fibrotic Enzyme Lysyl-oxidase levels through Inhibition of UPR in MPN cells2018
- Author(s)
  Megumi Suzuki, Jun Shuzuki, Megumi Koshiishi, Ichiro kawashima, Kei Nakajima, Keita Kirito
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08319
[Presentation] Aberrant Activation of NF-κB and Hypoxia Enhances Glycolytic Enzyme Hexokinase II Expression in B-Cell Lymphoma through Activation of HIF-12017
- Author(s)
  Nakajima, Kei Kirito, Keita Kawashima, Ichiro Koshiishi, Megumi Kumagai, Takuma Mitsumori, Toru
- Organizer
  第５９回米国血液学会
- Data Source
  KAKENHI-PROJECT-15K09470
[Presentation] Metformin inhibits the growth of JAK2V617F-harboring cells through direct inhibition of JAK2V617F2015
- Author(s)
  Ichiro kawashima, Keita Kirito
- Organizer
  第77回日本血液学会
- Place of Presentation
  石川県金沢市
- Year and Date
  2015-10-06
- Data Source
  KAKENHI-PROJECT-15K09470
[Presentation] Metformin Inhibits JAK2V617F Activity By Activating AMPK and PP2A Containing B56 Alpha Subunits in MPN Cells2015
- Author(s)
  Ichiro kawashima, Keita Kirito
- Organizer
  57th ASH Annual Meeting and Exposition
- Place of Presentation
  Orlando, FL, USA
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09470

1. KIRITO Keita (90306150)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
2. 三森徹 (80377514)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. 野崎由美 (80530104)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 中嶌圭 (20447709)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

KAWASHIMA Ichiro 川島 一郎

川島 一郎 カワシマ イチロウ

Research Projects

Research Products

Co-Researchers

GRP78の発現異常は骨髄増殖性腫瘍の血栓性病態を誘導するか？

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Enhanced ER stress response in MPN cells involved in development of myelofibrosis through secretion of GRP78

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of glucose metabolism in development of myelofibrosis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Bone Marrow Invasion of Small Cell Neuroendocrine Carcinoma of the Endometrium: A Diagnostic Pitfall Mimicking a Haematological Malignancy2019

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Glycolytic enzyme hexokinase II is a putative therapeutic target in B-cell malignant lymphoma2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Molecular response of CSF3R T618I harboring chronic neutrophilic leukemia after induction chemotherapy linked to cord blood transplantation2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metformin inhibits JAK2V617F activity in MPN cells by activating AMPK and PP2A complexes containing the B56alpha subunit2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Negative regulation of the LKB1/AMPK pathway by ERK in human acute myeloid leukemia cells2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] 骨髄増殖腫瘍における18F-FDG-PET/CT所見2019

Author(s)

Organizer

Data Source

[Presentation] APL細胞の細胞表面マーカーの特徴と限界2019

Author(s)

Organizer

Data Source

[Presentation] 日本における二次性骨髄線維症の予後予測モデルの比較検討2019

Author(s)

Organizer

Data Source

[Presentation] CSF3RT618I変異検出により診断することができた慢性好中球性白血病2019

Author(s)

Organizer

Data Source

[Presentation] Metformin suppresses expression of pre-fibrotic Enzyme Lysyl-oxidase levels through Inhibition of UPR in MPN cells2018

Author(s)

Organizer

Data Source

[Presentation] Metformin suppresses expression of pre-fibrotic Enzyme Lysyl-oxidase levels through Inhibition of UPR in MPN cells2018

Author(s)

Organizer

Data Source

[Presentation] Aberrant Activation of NF-κB and Hypoxia Enhances Glycolytic Enzyme Hexokinase II Expression in B-Cell Lymphoma through Activation of HIF-12017

Author(s)

Organizer

Data Source

KAWASHIMA Ichiro 川島一郎

川島一郎カワシマイチロウ